773 results on '"Southall, Noel"'
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2. Validation of a Natural Language Machine Learning Model for Safety Literature Surveillance
3. Progress toward a universal biomedical data translator
4. Prophylactic treatment with the c-Abl inhibitor, neurotinib, diminishes neuronal damage and the convulsive state in pilocarpine-induced mice
5. Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction
6. Defining clinical outcome pathways
7. Discovery of small molecule agonists of the Relaxin Family Peptide Receptor 2
8. Discovery of small molecule inhibitors that effectively disrupt IQGAP1-Cdc42 interaction in breast cancer cells
9. Validating ADME QSAR Models Using Marketed Drugs
10. Pandemic vaccines: a formidable challenge for pharmacovigilance
11. Clinical development times for innovative drugs
12. An Orally Efficacious Thyrotropin Receptor Ligand Inhibits Growth and Metastatic Activity of Thyroid Cancers.
13. Fluoxazolevir inhibits hepatitis C virus infection in humanized chimeric mice by blocking viral membrane fusion
14. A high-throughput screening to identify small molecules that suppress huntingtin promoter activity or activate huntingtin-antisense promoter activity
15. Identification of Small Molecule Inhibitors of a Mir155 Transcriptional Reporter in Th17 Cells
16. The NCATS Pharmaceutical Collection: a 10-year update
17. A randomized, proof-of-concept clinical trial on repurposing chlorcyclizine for the treatment of chronic hepatitis C
18. A large scale high-throughput screen identifies chemical inhibitors of phosphatidylinositol 4-kinase type II alpha
19. Advancing precision medicine with personalized drug screening
20. Validation of a Natural Language Machine Learning Model for Safety Literature Surveillance
21. Optimization of the first small-molecule relaxin/insulin-like family peptide receptor (RXFP1) agonists: Activation results in an antifibrotic gene expression profile
22. Pyruvate kinase M2 activators promote tetramer formation and suppress tumorigenesis
23. SU9516 Increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy
24. Synaptamide activates the adhesion GPCR GPR110 (ADGRF1) through GAIN domain binding
25. Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models
26. An integrative knowledge graph for rare diseases, derived from the Genetic and Rare Diseases Information Center (GARD)
27. Predicting liver cytosol stability of small molecules
28. Identification of Small Molecule Enhancers of Immunotherapy for Melanoma
29. Anxiolytic Drug FGIN-1-27 Ameliorates Autoimmunity by Metabolic Reprogramming of Pathogenic Th17 Cells
30. Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre;LSL-KrasG12D/+;Tp53R172H/+ (KPC) mice, a genetically engineered model of pancreatic cancer
31. Autocrine activation of JAK2 by IL-11 promotes platinum drug resistance
32. Structure–Activity Relationships of a Brain-Penetrant D3 Dopamine Receptor Negative Allosteric Modulator and Investigation of its Binding Site
33. Supplementary Table 1 from Identification of a Small-Molecule Inhibitor That Disrupts the SIX1/EYA2 Complex, EMT, and Metastasis
34. Supplemental Figures 1-6 from Identification of a Small-Molecule Inhibitor That Disrupts the SIX1/EYA2 Complex, EMT, and Metastasis
35. Supplementary Methods from Identification of a Small-Molecule Inhibitor That Disrupts the SIX1/EYA2 Complex, EMT, and Metastasis
36. Data from Identification of a Small-Molecule Inhibitor That Disrupts the SIX1/EYA2 Complex, EMT, and Metastasis
37. Supplemental Figure 1 from Targeting Estrogen Receptor Signaling with Fulvestrant Enhances Immune and Chemotherapy-Mediated Cytotoxicity of Human Lung Cancer
38. Supplemental Figure Legends from Identification of a Small-Molecule Inhibitor That Disrupts the SIX1/EYA2 Complex, EMT, and Metastasis
39. Supplemental Table 1 from Targeting Estrogen Receptor Signaling with Fulvestrant Enhances Immune and Chemotherapy-Mediated Cytotoxicity of Human Lung Cancer
40. Supplemental Materials and Methods from Targeting Estrogen Receptor Signaling with Fulvestrant Enhances Immune and Chemotherapy-Mediated Cytotoxicity of Human Lung Cancer
41. Data from Cardiac Glycosides Inhibit p53 Synthesis by a Mechanism Relieved by Src or MAPK Inhibition
42. Supplementary Figure Legends 1-4 from Cardiac Glycosides Inhibit p53 Synthesis by a Mechanism Relieved by Src or MAPK Inhibition
43. Supplementary Figures 1-4 from Cardiac Glycosides Inhibit p53 Synthesis by a Mechanism Relieved by Src or MAPK Inhibition
44. Identification of novel anti-hepatitis C virus agents by a quantitative high throughput screen in a cell-based infection assay
45. Small Molecule, NSC95397, Inhibits the CtBP1-Protein Partner Interaction and CtBP1-Mediated Transcriptional Repression
46. High-Throughput Viability Assay Using an Autonomously Bioluminescent Cell Line with a Bacterial Lux Reporter
47. Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation
48. Allosteric Inhibitors of the Eya2 Phosphatase Are Selective and Inhibit Eya2-mediated Cell Migration
49. An Overview of the Challenges in Designing, Integrating, and Delivering BARD: A Public Chemical-Biology Resource and Query Portal for Multiple Organizations, Locations, and Disciplines
50. High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer
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