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The ultraviolet-to-radio continuum spectral energy distributions are presented for all 75 galaxies in the Spitzer Infrared Nearby Galaxies Survey (SINGS). A principal component analysis of the sample shows that most of the sample's spectral variations stem from two underlying components, one representative of a galaxy with a low infrared-to-ultraviolet ratio and one representative of a galaxy with a high infrared-to-ultraviolet ratio. The influence of several parameters on the infrared-to-ultraviolet ratio is studied (e.g., optical morphology, disk inclination, far-infrared color, ultraviolet spectral slope, and star formation history). Consistent with our understanding of normal star-forming galaxies, the SINGS sample of galaxies in comparison to more actively star-forming galaxies exhibits a larger dispersion in the infrared-to-ultraviolet versus ultraviolet spectral slope correlation. Early type galaxies, exhibiting low star formation rates and high optical surface brightnesses, have the most discrepant infrared-to-ultraviolet correlation. These results suggest that the star formation history may be the dominant regulator of the broadband spectral variations between galaxies. Finally, a new discovery shows that the 24 micron morphology can be a useful tool for parametrizing the global dust temperature and ultraviolet extinction in nearby galaxies. The dust emission in dwarf/irregular galaxies is clumpy and warm accompanied by low ultraviolet extinction, while in spiral galaxies there is typically a much larger diffuse component of cooler dust and average ultraviolet extinction. For galaxies with nuclear 24 micron emission, the dust temperature and ultraviolet extinction are relatively high compared to disk galaxies., Comment: Accepted for publication in the Astrophysical Journal; Fixed radio flux density units (mJy)

(Abridged) Far ultraviolet to far infrared images of the nearby galaxy NGC5194, from Spitzer, GALEX, Hubble Space Telescope and ground--based data, are used to investigate local and global star formation, and the impact of dust extinction in HII-emitting knots. In the IR/UV-UV color plane, the NGC5194 HII knots show the same trend observed for normal star-forming galaxies, having a much larger dispersion than starburst galaxies. We identify the dispersion as due to the UV emission predominantly tracing the evolved, non-ionizing stellar population, up to ages 50-100 Myr. While in starbursts the UV light traces the current SFR, in NGC5194 it traces a combination of current and recent-past SFR. Unlike the UV emission, the monochromatic 24 micron luminosity is an accurate local SFR tracer for the HII knots in NGC5194; this suggests that the 24 micron emission carriers are mainly heated by the young, ionizing stars. However, preliminary results show that the ratio of the 24 micron emission to the SFR varies by a factor of a few from galaxy to galaxy. While also correlated with star formation, the 8 micron emission is not directly proportional to the number of ionizing photons. This confirms earlier suggestions that the carriers of the 8 micron emission are heated by more than one mechanism., Comment: 66 pages, 20 figures (Figures 1-4 are in JPEG format, figures 5-20 are embedded postscript files). Accepted for publication on the Astrophysical Journal