1. Thoracic Manifestations of Breast Cancer and Its Therapy
- Author
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Seog Hee Park, Hyeon Sook Kim, Myeong Im Ahn, Jung Im Jung, Seong Tai Hahn, Ki Jun Kim, Hak Hee Kim, Soon Beom Seo, Sun Wha Song, and Myeong Hee Chung
- Subjects
Adult ,medicine.medical_specialty ,Lung Neoplasms ,Pleural effusion ,Mammaplasty ,medicine.medical_treatment ,Breast Neoplasms ,Modified Radical Mastectomy ,Metastasis ,Heart Neoplasms ,Postoperative Complications ,Breast cancer ,Thoracic Diseases ,Antineoplastic Combined Chemotherapy Protocols ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Radiation Injuries ,Mastectomy ,Radical mastectomy ,Aged ,Pneumonitis ,Spinal Neoplasms ,Radiotherapy ,business.industry ,Bone metastasis ,Pneumonia ,Middle Aged ,Thoracic Neoplasms ,medicine.disease ,Pleural Effusion, Malignant ,Surgery ,Radiation therapy ,Seroma ,Lymphatic Metastasis ,Female ,Neoplasm Recurrence, Local ,Artifacts ,Tomography, X-Ray Computed ,business ,Spinal Cord Compression - Abstract
Breast cancer is the second most common cause of cancer-related death in women. In most patients, imaging demonstrates thoracic changes resulting from either treatment, complications of treatment, or tumor recurrence or metastasis. The postsurgical imaging appearance of the chest wall depends on the surgical method used (radical mastectomy, modified radical mastectomy, breast-conserving surgery, breast reconstruction). The most common surgery-related complication is seroma. Radiation therapy frequently causes radiation pneumonitis, which occurs approximately 4-12 weeks after the completion of therapy and is characteristically limited to the field of irradiation. Chemotherapy-related complications include cardiotoxicity, pneumonitis, and infection. Ultrasonography and computed tomography are more sensitive than physical examination for detecting local and regional recurrence. The thorax is a common site of metastasis, which may affect the lymph nodes, bone, lung, pleura, or heart and pericardium. Bone metastasis is usually evaluated with bone scintigraphy and may cause spinal cord compression, a serious complication that requires early diagnosis. Intrapulmonary metastasis may manifest as single or multiple pulmonary nodules, airspace pattern metastasis, lymphangitic metastasis, or endobronchial metastasis. Pleural metastasis usually manifests as pleural effusion, with or without a pleural mass. Familiarity with the spectrum of radiologic findings in breast cancer patients allows accurate image interpretation and correct diagnosis.
- Published
- 2004
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