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This work presents a Model Predictive Control (MPC) for the artificial pancreas, which is able to autonomously manage basal insulin injections in type 1 diabetic patients. Specifically, the MPC goal is to maintain the patients' blood glucose level inside the safe range of 70-180 mg/dL, acting on the insulin amount and respecting all the imposed constraints, taking into consideration also the Insulin On Board (IOB), to avoid excess of insulin infusion. MPC uses a model to make predictions of the system behaviour. In this work, due to the complexity of the diabetes disease that complicates the identification of a general physiological model, a data-driven learning method is employed instead. The Componentwise H\"{o}lder Kinky Inference (CHoKI) method is adopted, to have a customized controller for each patient. For the data collection phase and also to test the proposed controller, the virtual patients of the FDA-accepted UVA/Padova simulator are exploited. The proposed MPC is also tested on a modified version of the simulator, that takes into consideration also the variability of the insulin sensitivity. The final results are satisfying since the proposed controller reduces the time in hypoglycemia (which is more dangerous) if compared to the outcome obtained with the standard constant basal insulin therapy provided by the simulator, satisfying also the time in range requirements and avoiding long-term hyperglycemia events.

Effort has been expended to assess the relative merits of undertaking further decay-data measurements of the main fission-product contributors to the decay heat of neutron-irradiated fissile fuel and related actinides by means of Total Absorption Gamma-ray Spectroscopy (TAGS/TAS) and Discrete Gamma-ray Spectroscopy (DGS). This review has been carried out following similar work performed under the auspices of OECD/WPEC-Subgroup 25 (2005-2007) and the International Atomic Energy Agency (2010, 2014), and various highly relevant TAGS measurements completed as a consequence of such assessments. We present our recommendations for new decay-data evaluations, along with possible requirements for total absorption and discrete high-resolution gamma-ray spectroscopy studies that cover approximately 120 fission products and various isomeric states., Comment: Submitted to European Physical Journal A

Miller Range (MIL) 07687 is a peculiar carbonaceous chondrite officially classified as a CO3. However, it has been found to display unique petrographic properties that are atypical of this group. Moreover, Raman spectra of its polyaromatic carbonaceous matter does not reflect a structural order consistent with the metamorphic history of a type 3 chondrite. As a result, it has been suggested to be an ungrouped C2 chondrite with CO affinities, although it has not been fully excluded as a CO chondrite. The ambiguity of the meteorite classification is the motivation behind the present study. We conclude that MIL 07687 is a unique carbonaceous chondrite with possible affinities to CO, CM and/or some ungrouped carbonaceous chondrites. The difficulty in classifying this meteorite stems from (i) its heavily weathered nature, which interferes with the interpretation of our oxygen (O-)isotopic measurements (ii) the overlap in the petrographic and O-isotopic descriptions of various COs, CMs and ungrouped meteorites in the Meteoritical society database. Optical and infrared spectra are consistent with the meteorite unequilibrated nature and indicate that it is probably mildly aqueously altered. Despite traces of aqueous alteration having previously been described in MIL 07687, this is the first time that the presence of hydrated amorphous silicates is reported. In fact, our results show that its present hydration is beyond that of most CO3s, less than most CM2s, and comparable to primitive CR2s. Consequently, we support the meteorite s C2 ung label, although a CO2 or CM2 classification cannot be fully excluded.

The $\beta$ decays of the ground state (gs) and isomeric state (m) of $^{96}$Y have been studied with the total absorption $\gamma$-ray spectroscopy technique at the Ion Guide Isotope Separator On-Line facility. The separation of the 8$^{+}$ isomeric state from the 0$^{-}$ ground state was achieved thanks to the purification capabilities of the JYFLTRAP double Penning trap system. The $\beta$-intensity distributions of both decays have been independently determined. In the analyses the de-excitation of the 1581.6 keV level in $^{96}$Zr, in which conversion electron emission competes with pair production, has been carefully considered and found to have significant impact on the $\beta$-detector efficiency, influencing the $\beta$-intensity distribution obtained. Our results for $^{96\text{gs}}$Y (0$^+$) confirm the large ground state to ground state $\beta$-intensity probability, although a slightly larger value than reported in previous studies was obtained, amounting to $96.6_{-2.1}^{+0.3}\%$ of the total $\beta$ intensity. Given that the decay of $^{96\text{gs}}$Y is the second most important contributor to the reactor antineutrino spectrum between 5 and 7 MeV, the impact of the present results on reactor antineutrino summation calculations has been evaluated. In the decay of $^{96\text{m}}$Y (8$^{+}$), previously undetected $\beta$ intensity in transitions to states above 6 MeV has been observed. This shows the importance of total absorption $\gamma$-ray spectroscopy measurements of $\beta$ decays with highly fragmented de-excitation patterns. $^{96\text{m}}$Y (8$^{+}$) is a major contributor to reactor decay heat in uranium-plutonium and thorium-uranium fuels around 10 s after fission pulses, and the newly measured average $\beta$ and $\gamma$ energies differ significantly from the previous values in evaluated databases (...)

Measurements of the decay energy released as a function of time following the thermal neutron induced fission on $^{235}$U and $^{239,241}$Pu were performed in the 1970s at Oak Ridge National Laboratory with the purpose of quantifying possible Loss Of Coolant Accident scenarios. This decay energy, known in technical parlance as decay heat, is mainly composed of two terms, that of the electrons produced together with antineutrinos in the beta-minus decay of the neutron-rich fission products, and that of the gammas produced in the subsequent decay of excited nuclear levels. In this work we study if this extensive set of decay heat measurements can be used to assess the Reactor Antineutrino Anomaly, that is, the approximately 5\% deficit of electron antineutrinos produced by nuclear reactors, first deduced by Mention and collaborators in 2011, and observed by the major reactor antineutrino experiments near nuclear power plants since. With the assistance of nuclear databases, we are able to obtain the ratio of electron spectra under equilibrium conditions for $^{235}$U to $^{239}$Pu, in better agreement with the lower trend recently reported by Kopeikin and collaborators, as well as those for $^{235}$U to $^{241}$Pu and $^{241}$Pu to $^{239}$Pu, which do not agree well with those measured at the Insitut Laue-Langevin in the 1980s. We conclude that a new experimental campaign is needed to measure the electron spectra utilizing a high-resolution and signal-to-noise-ratio electron spectrometer and a highly precise fission normalization procedure., Comment: 5 pages, 6 figures

The large quantities of antineutrinos produced through the decay of fission fragments in nuclear reactors provide an opportunity to study the properties of these particles and investigate their use in reactor monitoring. The reactor antineutrino spectra are measured using specialized, large area detectors that detect antineutrinos through inverse beta decay, electron elastic scattering, or coherent elastic neutrino nucleus scattering; although, inverse beta decay is the only demonstrated method so far. Reactor monitoring takes advantage of the differences in the antineutrino yield and spectra resulting from uranium and plutonium fission providing an opportunity to estimate the fissile material composition in the reactor. Recent experiments reveal a deviation between the measured and calculated antineutrino flux and spectra indicating either the existence of yet undiscovered neutrino physics, uncertainties in the reactor source term calculation, incorrect nuclear data, or a combination of all three. To address the nuclear data that impact the antineutrino spectrum calculations and measurements, an international group of over 180 experts in antineutrino physics, reactor analysis, detector development, and nuclear data came together during the Workshop on Nuclear Data for Reactor Antineutrino Measurements (WoNDRAM) to discuss nuclear data needs and achieve concordance on a set of recommended priorities for nuclear data improvements. Three topical sessions provided a forum to gain consensus amongst the participants on the most important data improvements to address two goals: 1) understand the reactor anomaly and 2) improve the ability to monitor reactors using antineutrinos. This report summarizes the outcomes of the workshop discussions and the recommendations for nuclear data efforts that reduce reactor antineutrino measurement uncertainties., Comment: 26 pages

Beta-delayed neutron emission is important for nuclear structure and astrophysics as well as for reactor applications. Significant advances in nuclear experimental techniques in the past two decades have led to a wealth of new measurements that remain to be incorporated in the databases. We report on a coordinated effort to compile and evaluate all the available beta-delayed neutron emission data. The different measurement techniques have been assessed and the data have been compared with semi-microscopic and microscopic-macroscopic models. The new microscopic database has been tested against aggregate total delayed neutron yields, time-dependent group parameters in 6-and 8-group re-presentation, and aggregate delayed neutron spectra. New recommendations of macroscopic delayed-neutron data for fissile materials of interest to applications are also presented. The new Reference Database for Beta-Delayed Neutron Emission Data is available online at: http://www-nds.iaea.org/beta-delayed-neutron/database.html., Comment: 96 pages, IAEA CRP report, preliminary version

The General Antiparticle Spectrometer (GAPS) is an Antarctic balloon experiment designed for low-energy (0.1$-$0.3 GeV/$n$) cosmic antinuclei as signatures of dark matter annihilation or decay. GAPS is optimized to detect low-energy antideuterons, as well as to provide unprecedented sensitivity to low-energy antiprotons and antihelium nuclei. The novel GAPS antiparticle detection technique, based on the formation, decay, and annihilation of exotic atoms, provides greater identification power for these low-energy antinuclei than previous magnetic spectrometer experiments. This work reports the sensitivity of GAPS to detect antihelium-3 nuclei, based on full instrument simulation, event reconstruction, and realistic atmospheric influence simulations. The report of antihelium nuclei candidate events by AMS-02 has generated considerable interest in antihelium nuclei as probes of dark matter and other beyond the Standard Model theories. GAPS is in a unique position to detect or set upper limits on the cosmic antihelium nuclei flux in an energy range that is essentially free of astrophysical background. In three 35-day long-duration balloon flights, GAPS will be sensitive to an antihelium flux on the level of $1.3^{+4.5}_{-1.2}\cdot 10^{-6}\mathrm{m^{-2}sr^{-1}s^{-1}}(\mathrm{GeV}/n)^{-1}$ (95% confidence level) in the energy range of 0.11$-$0.3 GeV/$n$, opening a new window on rare cosmic physics., Comment: Accepted for publication at Astroparticle Physics, 13 pages, 5 figures

In $\beta$-decay studies the determination of the decay probability to the ground state of the daughter nucleus often suffers from large systematic errors. The difficulty of the measurement is related to the absence of associated delayed $\gamma$-ray emission. In this work we revisit the $4\pi\gamma-\beta$ method proposed by Greenwood and collaborators in the 1990s, which has the potential to overcome some of the experimental difficulties. Our interest is driven by the need to determine accurately the $\beta$-intensity distributions of fission products that contribute significantly to the reactor decay heat and to the antineutrinos emitted by reactors. A number of such decays have large ground state branches. The method is relevant for nuclear structure studies as well. Pertinent formulae are revised and extended to the special case of $\beta$-delayed neutron emitters, and the robustness of the method is demonstrated with synthetic data. We apply it to a number of measured decays that serve as test cases and discuss the features of the method. Finally, we obtain ground state feeding intensities with reduced uncertainty for four relevant decays that will allow future improvements in antineutrino spectrum and decay heat calculations using the summation method.

The decays of the $\beta$-delayed neutron emitters $^{137}$I and $^{95}$Rb have been studied with the total absorption $\gamma$-ray spectroscopy technique. The purity of the beams provided by the JYFLTRAP Penning trap at the ion guide isotope separator on-line facility in Jyv\"askyl\"a allowed us to carry out a campaign of isotopically pure measurements with the decay total absorption $\gamma$-ray spectrometer, a segmented detector composed of eighteen NaI(Tl) modules. The contamination coming from the interaction of neutrons with the spectrometer has been carefully studied, and we have tested the use of time differences between prompt $\gamma$-rays and delayed neutron interactions to eliminate this source of contamination. Due to the sensitivity of our spectrometer, we have found a significant amount of $\beta$-intensity to states above the neutron separation energy that de-excite by $\gamma$-rays, comparable to the neutron emission probability. The competition between $\gamma$ de-excitation and neutron emission has been compared with Hauser-Feshbach calculations, and it can be understood as a nuclear structure effect. In addition, we have studied the impact of the $\beta$-intensity distributions determined in this work on reactor decay heat and reactor antineutrino spectrum summation calculations. The robustness of our results is demonstrated by a thorough study of uncertainties, and with the reproduction of the spectra of the individual modules and the module-multiplicity gated spectra. This work represents the state-of-the-art of our analysis methodology for segmented total absorption spectrometers.

The $\beta$ intensity distributions of the decays of $^{100\text{gs},100\text{m}}$Nb and $^{102\text{gs},102\text{m}}$Nb have been determined using the Total Absorption $\gamma$-Ray Spectroscopy technique. The JYFLTRAP double Penning trap system was employed to disentangle the isomeric states involved, lying very close in energy, in a campaign of challenging measurements performed with the Decay Total Absorption $\gamma$-ray Spectrometer at the Ion Guide Isotope Separator On-Line facility in Jyv\"askyl\"a. The low-spin isomeric state of each niobium case was populated through the decay of the zirconium parent, that was treated as a contaminant. We have applied a method to extract this contamination, and additionally we have obtained $\beta$ intensity distributions for these zirconium decays. The $\beta$-strength distributions evaluated with these results were compared with calculations in quasiparticle random-phase approximation, suggesting a prolate configuration for the ground states of $^{100,102}$Zr. The footprint of the Pandemonium effect was found when comparing our results for the analyses of the niobium isotopes with previous decay data. The $\beta$-intensities of the decay of $^{102\text{m}}$Nb were obtained for the first time. A careful evaluation of the uncertainties was carried out, and the consistency of our results was validated taking advantage of the segmentation of our spectrometer. The final results were used as input in reactor summation calculations. A large impact on antineutrino spectrum calculations was already reported and here we detail the significant impact on decay heat calculations.

DTAS is a segmented total absorption {\gamma}-ray spectrometer developed for the DESPEC experiment at FAIR. It is composed of up to eighteen NaI(Tl) crystals. In this work we study the performance of this detector with laboratory sources and also under real experimental conditions. We present a procedure to reconstruct offline the sum of the energy deposited in all the crystals of the spectrometer, which is complicated by the effect of NaI(Tl) light-yield non-proportionality. The use of a system to correct for time variations of the gain in individual detector modules, based on a light pulse generator, is demonstrated. We describe also an event-based method to evaluate the summing-pileup electronic distortion in segmented spectrometers. All of this allows a careful characterization of the detector with Monte Carlo simulations that is needed to calculate the response function for the analysis of total absorption {\gamma}-ray spectroscopy data. Special attention was paid to the interaction of neutrons with the spectrometer, since they are a source of contamination in studies of \b{eta}-delayed neutron emitting nuclei.