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3. Surgical Treatment of Lumbar Spondylolisthesis

Author

Detwiler, P. W., Porter, R. W., Han, P. P., Karahalios, D. G., Masferrer, R., Sonntag, V. K. H., Cohadon, F., editor, Dolenc, V. V., editor, Antunes, J. Lobo, editor, Pickard, J. D., editor, Reulen, H.-J., editor, Sindou, M., editor, Strong, A. J., editor, de Tribolet, N., editor, Tulleken, C. A. F., editor, and Vapalahti, M., editor

Published
2000
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19. Comparison of dural grafts in Chiari decompression surgery: Review of the literature.

Author

Abla, A. A., Link, T., Fusco, D., Wilson, D. A., and Sonntag, V. K. H.

Subjects
ARNOLD-Chiari deformity, SURGICAL decompression, NEUROSURGERY, OPERATIVE surgery, CEREBELLUM abnormalities, HUMAN abnormalities
Abstract

Background: Decompression of Chiari malformation is a common procedure in both pediatric and adult neurosurgery. Although the necessity for some bony removal is universally accepted, other aspects of Chiari surgery are the subject of debate. The most controversial points include the optimal amount of bony removal, the use of duraplasty (and the type of material), the need for subarachnoid dissection, and the need for tonsillar shrinkage. Material and Methods: We critically reviewed the literature to elucidate the risks and benefits of different graft types and to clarify optimal treatment options therein. Based on our search results, 108 relevant articles were identified. With specific inclusion and exclusion criteria, we noted three studies that directly compared two types of dural substitutes in Chiari malformation surgery. Results: Our review did not support the superiority of either autologous or nonautologous grafts when duraplasty is employed. Our institutional experience, however, dictates that when the pericranium is available and of good quality, it should be utilized for duraplasty. It is non-immunogenic, inexpensive, and capable of creating a watertight closure with the dura. Conclusions: Discrepancies between the three comparative studies analyzed are likely attributable to increases in pericranial quality and thickness with maturity. Future randomized studies with large numbers and the power to resolve differences in the relatively low rates of complications in Chiari surgery are warranted. [ABSTRACT FROM AUTHOR]

Published
2010
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26. A Randomized, Controlled Trial of Methylprednisolone or Naloxone in the Treatment of Acute Spinal-Cord Injury

Author

BRACKEN, M. B., primary, SHEPARD, M. J., additional, COLLINS, W. F., additional, HOLFORD, T. R., additional, YOUNG, W., additional, BASKIN, D. S., additional, EISENBERG, H. M., additional, FLAMM, E., additional, LEOSUMMERS, L., additional, MAROON, J., additional, MARSHALL, L. F., additional, PEROT, P. L., additional, PIEPMEIER, J., additional, SONNTAG, V. K. H., additional, WAGNER, F. C., additional, WILBERGER, J. E., additional, and WINN, H. R., additional

Published
1991
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38. Near-infrared oxymeter biosensor prototype for non-invasive in vivoanalysis of rat brain oxygenation: effects of drugs of abuse

Author

Crespi, F, Donini, M, Bandera, A, Congestri, F, Formenti, F, Sonntag, V, Heidbreder, C, and Rovati, L

Abstract

The feasibility of non-invasive analysis of brain activities was studied in the attempt to overcome the major limitation of actual in vivomethodologies, i.e. invasiveness. Optic fibre probes were used as the optical head of a novel, highly sensitive near-infrared continuous wave spectroscopy (CW-NIR) instrument. This prototype was designed for non-invasive analysis of the two main forms of haemoglobin: oxy-haemoglobin (HbO2) and deoxy-haemoglobin (Hb), chromophores present in biological tissues. It was tested in peripheral tissue (human gastrocnemius muscle) and then reset to perform the measurement on rat brain. In animal studies, the optical head was firmly placed using stereotaxic apparatus upon the sagittal line of the head of anaesthetized adult rats, without any surgery. Then pharmacological treatments with saline (300 µl s.c.) amphetamine (2 mg kg?1) or nicotine (0.4 mg kg?1) were performed. Within 10-20 min amphetamine substantially increased HbO2and reduced Hb control levels. Nicotine produced a rapid initial increase followed by a decrease in HbO2. In contrast to amphetamine, nicotine treatment also reduced Hb and blood volume. These results support the capacity of our CW-NIR prototype to measure non-invasively HbO2and Hb levels in the rat brain, that are markers of the degree of tissue oxygenation, thus providing an index of blood levels and therefore of brain metabolism.

Published
2006
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41. Subspecialty Certification

Author

Wilberger, J. E., Hoffman, H. J., Fabi, R. A., Reilly, G. D., Tahmouresie, A., Alexander, E., Shuey, H. M., Sonntag, V. K. H., Pelofsky, S., and Goodman, J. M.

Published
1997
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47. Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury: Results of the Third National Acute Spinal Cord Injury randomized controlled trial

Author

Bracken, M. B., Shepard, M. J., Holford, T. R., Leo-Summers, L., Aldrich, E. F., Fazl, M., Fehlings, M., Daniel Herr, Hitchon, P. W., Marshall, L. F., Nockels, R. P., Pascale, V., Perot Jr, P. L., Piepmeier, J., Sonntag, V. K. H., Wagner, F., Wilberger, J. E., Winn, H. R., and Young, W.

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