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4. Advances in diagnosis and treatment of hepatorenal syndrome type of acute kidney injury in patients with liver cirrhosis

Author

SONG Tingxue, QI Xingshun, and GAO Fan

Subjects
therapy, urogenital system, diagnosis, review, lcsh:Diseases of the digestive system. Gastroenterology, lcsh:RC799-869, urologic and male genital diseases, hepatorenal syndrome, female genital diseases and pregnancy complications, live cirrhosis
Abstract

Acute kidney injury (AKI) is a common complication of liver cirrhosis and mainly manifests as a rapidly elevated serum creatinine level, a reduced glomerular filtration rate, and oliguria or anuria. Type 1 hepatorenal syndrome (HRS-1) is a special type of AKI, and patients with untreated HRS-1 have an extremely high risk of death. Early diagnosis and treatment are of great importance. This paper summarizes the latest diagnostic criteria for hepatorenal syndrome (HRS) type of AKI and research advances in the treatment of HRS-1.

Published
2017

5. Xuebijing Injection Combined with Antibiotics for the Treatment of Spontaneous Bacterial Peritonitis in Liver Cirrhosis: A Meta-Analysis

Author

Han, Dan, Wang, Ran, Yu, Yang, Sun, Mingyu, Teschke, Rolf, Romeiro, Fernando Gomes, Mancuso, Andrea, Song, Tingxue, Peng, Zhong, Han, Bing, Zhou, Xinmiao, Bao, Wenchun, Li, Qianqian, Zheng, Kexin, Li, Yingying, Bai, Zhaohui, Guo, Xiaozhong, and Qi, Xingshun

Subjects
Article Subject
Abstract

Background and Aim. Spontaneous bacterial peritonitis (SBP) is one of the most common complications of liver cirrhosis. Antibiotics are the main treatment regimen of SBP. Traditional Chinese medicine Xuebijing injection has been used in such patients. Our study aimed to overview the efficacy of Xuebijing injection combined with antibiotics for the treatment of SBP. Method. We searched the PubMed, Embase, China National Knowledge Infrastructure, VIP, and Wanfang databases. The search items included “Xuebijing”, “peritonitis”, “liver cirrhosis”, and “random” to identify all relevant randomized controlled trials (RCTs). The Cochrane risk of bias tool was used to assess the study quality. The odd ratios (ORs) with 95% confidence intervals (CIs) were calculated by using a random-effect model. Heterogeneity was also calculated. Results. A total of 9 RCTs were included. The study quality was unsatisfied. The overall (OR = 2.95, 95% CI = 1.97–4.42, p

Published
2018
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11. Xuebijing injection combined with antibiotics for the treatment of spontaneous bacterial peritonitis in liver cirrhosis : a meta-analysis

Author

Xu, Yuan, Han, Dan, Wang, Ran, Yu, Yang, Sun, Mingyu, Teschke, Rolf, Romeiro, Fernando Gomes, Mancuso, Andrea, Song, Tingxue, Peng, Zhong, Han, Bing, Zhou, Xinmiao, Bao, Wenchun, Li, Qianqian, Zheng, Kexin, Li, Yingying, Bai, Zhaohui, Guo, Xiaozhong, Qi, Xingshun, Xu, Yuan, Han, Dan, Wang, Ran, Yu, Yang, Sun, Mingyu, Teschke, Rolf, Romeiro, Fernando Gomes, Mancuso, Andrea, Song, Tingxue, Peng, Zhong, Han, Bing, Zhou, Xinmiao, Bao, Wenchun, Li, Qianqian, Zheng, Kexin, Li, Yingying, Bai, Zhaohui, Guo, Xiaozhong, and Qi, Xingshun

Abstract

Background and Aim. Spontaneous bacterial peritonitis (SBP) is one of the most common complications of liver cirrhosis. Antibiotics are the main treatment regimen of SBP. Traditional Chinese medicine Xuebijing injection has been used in such patients. Our study aimed to overview the efficacy of Xuebijing injection combined with antibiotics for the treatment of SBP. Method. We searched the PubMed, Embase, China National Knowledge Infrastructure, VIP, and Wanfang databases. The search items included "Xuebijing", "peritonitis", "liver cirrhosis", and "random" to identify all relevant randomized controlled trials (RCTs). The Cochrane risk of bias tool was used to assess the study quality. The odd ratios (ORs) with 95% confidence intervals (CIs) were calculated by using a random-effect model. Heterogeneity was also calculated. Results. A total of 9 RCTs were included. The study quality was unsatisfied. The overall (OR = 2.95, 95% CI = 1.97–4.42, p<0.00001) and complete (OR = 2.18, 95% CI = 1.57–3.04, p<0.00001) responses were significantly higher in the Xuebijing injection combined with antibiotics group than the antibiotics alone group. The incidence of cirrhosis related complications, including hepatic encephalopathy and hepatorenal syndrome, was lower in the Xuebijing injection combined with antibiotics group than the antibiotics alone group. No significant heterogeneity was observed among studies. Conclusion. Additional use of Xuebijing injection may improve the efficacy of antibiotics for the treatment of SBP in liver cirrhosis. However, due to a low level of current evidence, we did not establish any recommendation regarding the use of Xuebijing injection for the treatment of SBP.

Published
2018

12. Neutrophil to lymphocyte ratio and albumin-bilirubin score for predicting the in-hospital mortality of hepatocellular carcinoma with acute upper gastrointestinal bleeding

Author

Peng, Zhong, primary, He, Zhangxiu, additional, Guo, Xiaozhong, additional, Tacke, Frank, additional, Yang, Sien-Sing, additional, Sugawara, Yasuhiko, additional, Han, Tao, additional, Deng, Han, additional, Wang, Ran, additional, Han, Dan, additional, Song, Tingxue, additional, Mancuso, Andrea, additional, Romeiro, Fernando Gomes, additional, and Qi, Xingshun, additional

Published
2017
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13. Impact of elevated urine leukocyte and bacteria count per high-power field on the in-hospital outcome of patients with liver cirrhosis

Author

Han, Dan, primary, Wang, Ran, additional, Yu, Yang, additional, Yang, Sien-Sing, additional, Mueller, Sebastian, additional, Romeiro, Fernando Gomes, additional, Song, Tingxue, additional, Deng, Han, additional, Li, Jing, additional, Peng, Zhong, additional, Li, Yibing, additional, Guo, Xiaozhong, additional, and Qi, Xingshun, additional

Published
2017
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