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3. Emergence of a ST248Pasteur-ST1068Oxford Carbapenem Resistance Acinetobacter pittii Clinical Isolate in China, Co-Harboring OXA-58 and OXA-500 Carbapenemases

Author

Tian,Chongmei, Song,Jianqin, Huang,Delian, Wang,Siwei, Zhao,Yaping, Fu,Liping, Fan,Xueyu, Ma,Tianhong, Bai,Yongfeng, Tian,Chongmei, Song,Jianqin, Huang,Delian, Wang,Siwei, Zhao,Yaping, Fu,Liping, Fan,Xueyu, Ma,Tianhong, and Bai,Yongfeng

Abstract

Chongmei Tian,1,* Jianqin Song,2,* Delian Huang,3 Siwei Wang,4 Yaping Zhao,1 Liping Fu,1 Xueyu Fan,5 Tianhong Ma,6 Yongfeng Bai5 1Department of Pharmacy, Shaoxing Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University, Shaoxing, Zhejiang, 312000, People’s Republic of China; 2Department of Traditional Chinese Medicine, Hangzhou Linping District Hospital of Integrated Chinese and Western Medicine, Hangzhou, People’s Republic of China; 3School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, 310053, People’s Republic of China; 4Core Facility, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People’s Hospital, Quzhou, 324000, People’s Republic of China; 5Department of Clinical Laboratory, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People’s Hospital, Quzhou, 324000, People’s Republic of China; 6Department of Pharmacy, Jiaxing Hospital of Traditional Chinese Medicine, Jiaxing, 314001, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yongfeng Bai; Tianhong Ma, Email bai.yongfeng@163.com; 15990312207@163.com

Published
2023

4. Emergence of a ST248Pasteur-ST1068Oxford Carbapenem Resistance Acinetobacter pittii Clinical Isolate in China, Co-Harboring OXA-58 and OXA-500 Carbapenemases.

Author

Tian, Chongmei, Song, Jianqin, Huang, Delian, Wang, Siwei, Zhao, Yaping, Fu, Liping, Fan, Xueyu, Ma, Tianhong, and Bai, Yongfeng

Subjects
ACINETOBACTER, MEDICAL sciences, CARBAPENEM-resistant bacteria, NUCLEIC acids, BACTERIAL genomes
Abstract

We further mapped our genome to the p17-84 OXA plasmid (accession number: CP059478) (Figure 1B), which is located in an ST63 pandrug-resistant I A. pittii i .[15] High nucleotide sequence identity was observed for some of the contigs in the TCM2 genome with p17-84 OXA (Figure 1C). Identified resistance genes were correlated with the actual antimicrobial resistance phenotype of the strain and a I bla i SB OXA-58 sb -bearing plasmid should be harbored by the TCM2 strain. Consequently, we concluded that there was a I bla i SB OXA-58 sb -bearing plasmid in the TCM2 strain, which was probably obtained from other I A. pittii i and I A. nosocomialis i strains collected in China in 2012 and 2014, respectively (Supplementary Table 2). [Extracted from the article]

Published
2023
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