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3. A skin-integrated multimodal haptic interface for immersive tactile feedback

Author

Huang, Ya, Zhou, Jingkun, Ke, Pingchuan, Guo, Xu, Yiu, Chun Ki, Yao, Kuanming, Cai, Shaoyu, Li, Dengfeng, Zhou, Yu, Li, Jian, Wong, Tsz Hung, Liu, Yiming, Li, Lei, Gao, Yuyu, Huang, Xingcan, Li, Hu, Li, Jiyu, Zhang, Binbin, Chen, Zhenlin, Zheng, Huanxi, Yang, Xingyu, Gao, Haichen, Zhao, Zichen, Guo, Xu, Song, Enming, Wu, Hui, Wang, Zuankai, Xie, Zhaoqian, Zhu, Kening, and Yu, Xinge

Published
2023
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6. Publisher Correction: A skin-integrated multimodal haptic interface for immersive tactile feedback

Author

Huang, Ya, Zhou, Jingkun, Ke, Pingchuan, Guo, Xu, Yiu, Chun Ki, Yao, Kuanming, Cai, Shaoyu, Li, Dengfeng, Zhou, Yu, Li, Jian, Wong, Tsz Hung, Liu, Yiming, Li, Lei, Gao, Yuyu, Huang, Xingcan, Li, Hu, Li, Jiyu, Zhang, Binbin, Chen, Zhenlin, Zheng, Huanxi, Yang, Xingyu, Gao, Haichen, Zhao, Zichen, Guo, Xu, Song, Enming, Wu, Hui, Wang, Zuankai, Xie, Zhaoqian, Zhu, Kening, and Yu, Xinge

Published
2023
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7. Encoding of tactile information in hand via skin-integrated wireless haptic interface

Author

Yao, Kuanming, Zhou, Jingkun, Huang, Qingyun, Wu, Mengge, Yiu, Chun Ki, Li, Jian, Huang, Xingcan, Li, Dengfeng, Su, Jingyou, Hou, Senlin, Liu, Yiming, Huang, Ya, Tian, Ziyan, Li, Jiyu, Li, Hu, Shi, Rui, Zhang, Binbin, Zhu, Jingyi, Wong, Tsz Hung, Jia, Huiling, Gao, Zhan, Gao, Yuyu, Zhou, Yu, Park, Wooyoung, Song, Enming, Han, Mengdi, Zhang, Haixia, Yu, Junsheng, Wang, Lidai, Li, Wen Jung, and Yu, Xinge

Published
2022
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12. Capacitively coupled arrays of multiplexed flexible silicon transistors for long-term cardiac electrophysiology

Author

Fang, Hui, Yu, Ki Jun, Gloschat, Christopher, Yang, Zijian, Song, Enming, Chiang, Chia-Han, Zhao, Jianing, Won, Sang Min, Xu, Siyi, Trumpis, Michael, Zhong, Yiding, Han, Seung Won, Xue, Yeguang, Xu, Dong, Choi, Seo Woo, Cauwenberghs, Gert, Kay, Matthew, Huang, Yonggang, Viventi, Jonathan, Efimov, Igor R, and Rogers, John A

Subjects
Engineering, Electronics, Sensors and Digital Hardware, Cardiovascular, Heart Disease, Prevention, Biomedical engineering
Abstract

Advanced capabilities in electrical recording are essential for the treatment of heart-rhythm diseases. The most advanced technologies use flexible integrated electronics; however, the penetration of biological fluids into the underlying electronics and any ensuing electrochemical reactions pose significant safety risks. Here, we show that an ultrathin, leakage-free, biocompatible dielectric layer can completely seal an underlying layer of flexible electronics while allowing for electrophysiological measurements through capacitive coupling between tissue and the electronics, and thus without the need for direct metal contact. The resulting current-leakage levels and operational lifetimes are, respectively, four orders of magnitude smaller and between two and three orders of magnitude longer than those of any other flexible-electronics technology. Systematic electrophysiological studies with normal, paced and arrhythmic conditions in Langendorff hearts highlight the capabilities of the capacitive-coupling approach. Our technology provides a realistic pathway towards the broad applicability of biocompatible, flexible electronic implants.

Published
2017

14. Miniaturized electromechanical devices for the characterization of the biomechanics of deep tissue

Author

Song, Enming, Xie, Zhaoqian, Bai, Wubin, Luan, Haiwen, Ji, Bowen, Ning, Xin, Xia, Yu, Baek, Janice Mihyun, Lee, Yujin, Avila, Raudel, Chen, Huang-Yu, Kim, Jae-Hwan, Madhvapathy, Surabhi, Yao, Kuanming, Li, Dengfeng, Zhou, Jingkun, Han, Mengdi, Won, Sang Min, Zhang, Xinyuan, Myers, Daniel J., Mei, Yongfeng, Guo, Xu, Xu, Shuai, Chang, Jan-Kai, Yu, Xinge, Huang, Yonggang, and Rogers, John A.

Published
2021
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15. Conformal Fixation Strategies and Bioadhesives for Soft Bioelectronics.

Author

Park, Jaejin, Kim, Hyun Woo, Lim, Selin, Yi, Hoon, Wu, Zhongyuan, Kwon, In Gyu, Yeo, Woon‐Hong, Song, Enming, and Yu, Ki Jun

Subjects
BIOMEDICAL adhesives, BIOELECTRONICS, ARTIFICIAL implants, HUMAN ecology, HUMAN body
Abstract

Flexible wearable and implantable devices are contributing to the healthcare field by enabling intuitive interfaces with the tissues of human body through their thin form factors, which enable more accurate monitoring of signals and effective delivery of therapy. The development of such devices is accompanied with an increasing interest in strategies and technologies for conformally fixing and adhering flexible biomedical devices in place to acquire high‐quality biosignals over a long period, even with the subtle movements of the target. Owing to the various mechanical properties and wet or dynamic environments of human tissues, it is necessary to use different adhesion strategies that consider the biocompatibility and cohesive properties for each case. This paper provides an in‐depth analysis of recent bio‐adhesives technologies and their practical applications in the healthcare field by classifying them into: 1) Conventional Fixation, 2) Mechanical Fixation, and 3) Chemical Adhesion, based on the mechanism, and 4) Functional Adhesion and 5) Biomimetic Adhesion, based on the unique properties. Furthermore, the principles and detailed mechanisms of each adhesion strategy based on the design and characteristics of the bioadhesives are thoroughly reviewed to provide valuable insights and an overall summary of the prospects and challenges of future bioadhesives technology. [ABSTRACT FROM AUTHOR]

Published
2024
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17. Self‐Rolled‐Up Ultrathin Single‐Crystalline Silicon Nanomembranes for On‐Chip Tubular Polarization Photodetectors

Author

Wu, Binmin, primary, Zhang, Ziyu, additional, Zheng, Zhi, additional, Cai, Tianjun, additional, You, Chunyu, additional, Liu, Chang, additional, Li, Xing, additional, Wang, Yang, additional, Wang, Jinlong, additional, Li, Hongbin, additional, Song, Enming, additional, Cui, Jizhai, additional, Huang, Gaoshan, additional, and Mei, Yongfeng, additional

Published
2023
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19. Catheter-integrated soft multilayer electronic arrays for multiplexed sensing and actuation during cardiac surgery

Author

Han, Mengdi, Chen, Lin, Aras, Kedar, Liang, Cunman, Chen, Xuexian, Zhao, Hangbo, Li, Kan, Faye, Ndeye Rokhaya, Sun, Bohan, Kim, Jae-Hwan, Bai, Wubin, Yang, Quansan, Ma, Yuhang, Lu, Wei, Song, Enming, Baek, Janice Mihyun, Lee, Yujin, Liu, Clifford, Model, Jeffrey B., Yang, Guanjun, Ghaffari, Roozbeh, Huang, Yonggang, Efimov, Igor R., and Rogers, John A.

Published
2020
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21. One-step rolling fabrication of VO 2 tubular bolometers with polarization-sensitive and omnidirectional detection

Author

Wu, Binmin, primary, Zhang, Ziyu, additional, Chen, Bingxin, additional, Zheng, Zhi, additional, You, Chunyu, additional, Liu, Chang, additional, Li, Xing, additional, Wang, Jinlong, additional, Wang, Yunqi, additional, Song, Enming, additional, Cui, Jizhai, additional, An, Zhenghua, additional, Huang, Gaoshan, additional, and Mei, Yongfeng, additional

Published
2023
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25. Ultrathin, Soft, Bioresorbable Organic Electrochemical Transistors for Transient Spatiotemporal Mapping of Brain Activity (Adv. Sci. 14/2023)

Author

Wu, Mengge, primary, Yao, Kuanming, additional, Huang, Ningge, additional, Li, Hu, additional, Zhou, Jingkun, additional, Shi, Rui, additional, Li, Jiyu, additional, Huang, Xingcan, additional, Li, Jian, additional, Jia, Huiling, additional, Gao, Zhan, additional, Wong, Tsz Hung, additional, Li, Dengfeng, additional, Hou, Sihui, additional, Liu, Yiming, additional, Zhang, Shiming, additional, Song, Enming, additional, Yu, Junsheng, additional, and Yu, Xinge, additional

Published
2023
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27. Ultrathin, transferred layers of thermally grown silicon dioxide as biofluid barriers for biointegrated flexible electronic systems

Author

Fang, Hui, Zhao, Jianing, Yu, Ki Jun, Song, Enming, Farimani, Amir Barati, Chiang, Chia-Han, Jin, Xin, Xue, Yeguang, Xu, Dong, Du, Wenbo, Seo, Kyung Jin, Zhong, Yiding, Yang, Zijian, Won, Sang Min, Fang, Guanhua, Choi, Seo Woo, Chaudhuri, Santanu, Huang, Yonggang, Alam, Muhammad Ashraful, Viventi, Jonathan, Aluru, N. R., and Rogers, John A.

Published
2016

28. Smart MXene‐based bioelectronic devices as wearable health monitor for sensing human physiological signals.

Author

Han, Sancan, Zou, Mingchen, Pu, Xinxin, Lu, Yifei, Tian, Yuecheng, Li, Huijun, Liu, Yi, Wu, Fangyu, Huang, Ningge, Shen, Meihua, Song, Enming, and Wang, Ding

Subjects
PRESSURE sensors, BIOMEDICAL materials, INTELLIGENT control systems, FACIAL expression, STRUCTURAL health monitoring, WEARABLE technology, ELECTRONIC surveillance
Abstract

Biosafe wearable healthcare monitor has attracted significant attention owing to their applicability to wearable electronics. However, the narrow sensing range and poor response limit the application of flexible devices for comprehensive monitoring of human health‐related physiological signals (i.e., pulse diagnosis). Critical challenges remain in the development of biocompatible materials and the design of flexible bio‐integrated platforms for these purposes, targeting performance approaching those of conventional wafer‐based technologies and long‐term operational stability. In this context, this work presents a robust and flexible MXene/polydopamine (PDA)‐composite‐film‐based pressure sensor in a portable/wearable fashion, which establishes a unique intercalated spherical‐like PDA molecules structure, thereby resulting in excellent sensing performance. The MXene/PDA‐based pressure sensor has sensitivity of up to 138.8 kPa−1 in the pressure range of 0.18–6.20 kPa with fast response and recovery speed (t1 < 100 ms; t2< 50 ms). Associated embodiment involves real‐time precise measurements of a variety of health‐related physiological signals, ranging from wrist pulse, to finger motions, to vocalization and to facial expressions, with high sensitivity and accuracy. Studies on human subjects establish the clinical significance of these devices for future opportunities of health monitoring and intelligent control to predict and diagnose diseases. [ABSTRACT FROM AUTHOR]

Published
2023
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34. Mapping of Spatiotemporal Auricular Electrophysiological Signals Reveals Human Biometric Clusters

Author

Huang, Qingyun, primary, Wu, Cong, additional, Hou, Senlin, additional, Yao, Kuanming, additional, Sun, Hui, additional, Wang, Yufan, additional, Chen, Yikai, additional, Law, Junhui, additional, Yang, Mingxiao, additional, Chan, Ho‐yin, additional, Roy, Vellaisamy A. L., additional, Zhao, Yuliang, additional, Wang, Dong, additional, Song, Enming, additional, Yu, Xinge, additional, Lao, Lixing, additional, Sun, Yu, additional, and Li, Wen Jung, additional

Published
2022
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36. Rolling origami of vanadium dioxide nanomembranes for enhanced multi-level solar modulation

Author

Li, Xing, primary, Cao, Cuicui, additional, Liu, Chang, additional, He, Wenhao, additional, Wu, Kaibo, additional, Wang, Yang, additional, Xu, Borui, additional, Tian, Ziao, additional, Song, Enming, additional, Cui, Jizhai, additional, Huang, Gaoshan, additional, Zheng, Changlin, additional, Di, Zengfeng, additional, Cao, Xun, additional, and Mei, Yongfeng, additional

Published
2022
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37. Implantable Electronic Medicine Enabled by Bioresorbable Microneedles for Wireless Electrotherapy and Drug Delivery

Author

Huang, Ya, primary, Li, Hu, additional, Hu, Tianli, additional, Li, Jian, additional, Yiu, Chun Ki, additional, Zhou, Jingkun, additional, Li, Jiyu, additional, Huang, Xingcan, additional, Yao, Kuanming, additional, Qiu, Xiao, additional, Zhou, Yu, additional, Li, Dengfeng, additional, Zhang, Binbin, additional, Shi, Rui, additional, Liu, Yiming, additional, Wong, Tsz Hung, additional, Wu, Mengge, additional, Jia, Huiling, additional, Gao, Zhan, additional, Zhang, Zhibiao, additional, He, Jiahui, additional, Zheng, Mengjia, additional, Song, Enming, additional, Wang, Lidai, additional, Xu, Chenjie, additional, and Yu, Xinge, additional

Published
2022
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38. Submillimeter-scale multimaterial terrestrial robots

Author

Han, Mengdi, primary, Guo, Xiaogang, additional, Chen, Xuexian, additional, Liang, Cunman, additional, Zhao, Hangbo, additional, Zhang, Qihui, additional, Bai, Wubin, additional, Zhang, Fan, additional, Wei, Heming, additional, Wu, Changsheng, additional, Cui, Qinghong, additional, Yao, Shenglian, additional, Sun, Bohan, additional, Yang, Yiyuan, additional, Yang, Quansan, additional, Ma, Yuhang, additional, Xue, Zhaoguo, additional, Kwak, Jean Won, additional, Jin, Tianqi, additional, Tu, Qing, additional, Song, Enming, additional, Tian, Ziao, additional, Mei, Yongfeng, additional, Fang, Daining, additional, Zhang, Haixia, additional, Huang, Yonggang, additional, Zhang, Yihui, additional, and Rogers, John A., additional

Published
2022
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39. Implantable Electronic Medicine Enabled by Bioresorbable Microneedles for Wireless Electrotherapy and Drug Delivery

Author

Huang, Ya, Li, Hu, Hu, Tianli, Li, Jian, Yiu, Chun Ki, Zhou, Jingkun, Li, Jiyu, Huang, Xingcan, Yao, Kuanming, Qiu, Xiao, Zhou, Yu, Li, Dengfeng, Zhang, Binbin, Shi, Rui, Liu, Yiming, Wong, Tsz Hung, Wu, Mengge, Jia, Huiling, Gao, Zhan, Zhang, Zhibiao, He, Jiahui, Zheng, Mengjia, Song, Enming, Wang, Lidai, Xu, Chenjie, Yu, Xinge, Huang, Ya, Li, Hu, Hu, Tianli, Li, Jian, Yiu, Chun Ki, Zhou, Jingkun, Li, Jiyu, Huang, Xingcan, Yao, Kuanming, Qiu, Xiao, Zhou, Yu, Li, Dengfeng, Zhang, Binbin, Shi, Rui, Liu, Yiming, Wong, Tsz Hung, Wu, Mengge, Jia, Huiling, Gao, Zhan, Zhang, Zhibiao, He, Jiahui, Zheng, Mengjia, Song, Enming, Wang, Lidai, Xu, Chenjie, and Yu, Xinge

Abstract

A combined treatment using medication and electro-stimulation increases its effectiveness in comparison with one treatment alone. However, the organic integration of two strategies in one miniaturized system for practical usage has seldom been reported. This article reports an implantable electronic medicine based on bioresorb-able microneedle devices that is activated wirelessly for electro-stimulation and sustainable delivery of anti-inflammatory drugs. The electronic medicine is composed of a radio frequency wireless power transmission system and a drug-loaded microneedle structure, all fabricated with bioresorbable materials. In a rat skeletal muscle injury model, periodic electrostimulation regulates cell behaviors and tissue regeneration while the anti-inflammatory drugs prevent inflammation, which ultimately enhance the skeletal muscle regeneration. Finally, the electronic medicine is fully bioresorbable, excluding the second surgery for device removal.

Published
2022

40. Transient, Implantable, Ultrathin Biofuel Cells Enabled by Laser-Induced Graphene and Gold Nanoparticles Composite

Author

Huang, Xingcan, primary, Li, Hu, additional, Li, Jiyu, additional, Huang, Libei, additional, Yao, Kuanming, additional, Yiu, Chun Ki, additional, Liu, Yiming, additional, Wong, Tsz Hung, additional, Li, Dengfeng, additional, Wu, Mengge, additional, Huang, Ya, additional, Gao, Zhan, additional, Zhou, Jingkun, additional, Gao, Yuyu, additional, Li, Jian, additional, Jiao, Yanli, additional, Shi, Rui, additional, Zhang, Binbin, additional, Hu, Bofan, additional, Guo, Qinglei, additional, Song, Enming, additional, Ye, Ruquan, additional, and Yu, Xinge, additional

Published
2022
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41. Stretchable Sweat‐Activated Battery in Skin‐Integrated Electronics for Continuous Wireless Sweat Monitoring

Author

Liu, Yiming, primary, Huang, Xingcan, additional, Zhou, Jingkun, additional, Yiu, Chun Ki, additional, Song, Zhen, additional, Huang, Wei, additional, Nejad, Sina Khazaee, additional, Li, Hu, additional, Wong, Tsz Hung, additional, Yao, Kuanming, additional, Zhao, Ling, additional, Yoo, Woojung, additional, Park, Wooyoung, additional, Li, Jiyu, additional, Huang, Ya, additional, Lam, Hiuwai Raymond, additional, Song, Enming, additional, Guo, Xu, additional, Wang, Yanwei, additional, Dai, Zhenxue, additional, Chang, Lingqian, additional, Li, Wen Jung, additional, Xie, Zhaoqian, additional, and Yu, Xinge, additional

Published
2022
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43. Epidermal self-powered sweat sensors for glucose and lactate monitoring

Author

Huang, Xingcan, primary, Li, Jiyu, additional, Liu, Yiming, additional, Wong, Tszhung, additional, Su, Jingyou, additional, Yao, Kuanming, additional, Zhou, Jingkun, additional, Huang, Ya, additional, Li, Hu, additional, Li, Dengfeng, additional, Wu, Mengge, additional, Song, Enming, additional, Han, Shijiao, additional, and Yu, Xinge, additional

Published
2021
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44. Thin, soft, garment‐integrated triboelectric nanogenerators for energy harvesting and human machine interfaces

Author

Liu, Yiming, primary, Yiu, Chunki, additional, Jia, Huiling, additional, Wong, Tszhung, additional, Yao, Kuanming, additional, Huang, Ya, additional, Zhou, Jingkun, additional, Huang, Xingcan, additional, Zhao, Ling, additional, Li, Dengfeng, additional, Wu, Mengge, additional, Gao, Zhan, additional, He, Jiahui, additional, Song, Enming, additional, and Yu, Xinge, additional

Published
2021
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46. Bioresorbable Multilayer Photonic Cavities as Temporary Implants for Tether-Free Measurements of Regional Tissue Temperatures

Author

Bai, Wubin, primary, Irie, Masahiro, additional, Liu, Zhonghe, additional, Luan, Haiwen, additional, Franklin, Daniel, additional, Nandoliya, Khizar, additional, Guo, Hexia, additional, Zang, Hao, additional, Weng, Yang, additional, Lu, Di, additional, Wu, Di, additional, Wu, Yixin, additional, Song, Joseph, additional, Han, Mengdi, additional, Song, Enming, additional, Yang, Yiyuan, additional, Chen, Xuexian, additional, Zhao, Hangbo, additional, Lu, Wei, additional, Monti, Giuditta, additional, Stepien, Iwona, additional, Kandela, Irawati, additional, Haney, Chad R., additional, Wu, Changsheng, additional, Won, Sang Min, additional, Ryu, Hanjun, additional, Rwei, Alina, additional, Shen, Haixu, additional, Kim, Jihye, additional, Yoon, Hong-Joon, additional, Ouyang, Wei, additional, Liu, Yihan, additional, Suen, Emily, additional, Chen, Huang-yu, additional, Okina, Jerry, additional, Liang, Jushen, additional, Huang, Yonggang, additional, Ameer, Guillermo A., additional, Zhou, Weidong, additional, and Rogers, John A., additional

Published
2021
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48. Skin-Integrated Electromechanical Systems for Characterization of Deep Tissue Biomechanics

Author

Rogers, John, primary, Song, Enming, additional, Xie, Zhaoqian, additional, Bai, Wubin, additional, Luan, Haiwen, additional, Ji, Bowen, additional, Ning, Xin, additional, Xia, Yu, additional, Baek, Janice Mihyun, additional, Lee, Yujin, additional, Avila, Raudel, additional, Chen, Huang-Yu, additional, Kim, Jae-Hwan, additional, Madhvapathi, Surabhi, additional, Yao, Kuanming, additional, Won, Sang, additional, Zhang, Xinyuan, additional, Myers, Daniel, additional, Mei, Yongfeng, additional, Guo, Xu, additional, Xu, Shuai, additional, Yu, Xinge, additional, and Huang, Yonggang, additional

Published
2020
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