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In this study, we report on the green synthesis, characterization, and anticancer activity of zinc oxide nanoparticles (ZnO NPs) prepared using extracts of guava leaves. The ZnO NPs were successfully synthesized using a simple and eco‐friendly method. Then, the synthesized NPs were characterized using various techniques including Fourier‐transform infrared spectroscopy, X‐ray diffraction, scanning electron microscopy, and transmission electron microscopy. The results confirmed the formation of ZnO NPs with an average size of approximately 20 nm, along with a spherical morphology and well‐defined boundaries. The anticancer activity of the synthesized NPs was evaluated against different cancer cell lines, including A549 (lung cancer), HeLa (cervical cancer), and MCF7 (breast cancer), as well as normal human dermal fibroblast (HDF) cells. The analysis showed that the ZnO NPs exhibited significant anticancer activity, especially against the MCF7 and HeLa cancer cell lines, along with relatively low toxicity toward HDF cells. These findings highlight the potential of ZnO NPs synthesized using guava leaf extract as promising candidates for biomedical applications, particularly in cancer therapy. [ABSTRACT FROM AUTHOR]

Sustainable development is a subject of study and consideration by scientists and policymakers, especially the sustainable development of the night-time economy. The night-time economy refers to the various economic activities and businesses that primarily operate during the evening and night hours, typically from 6 p.m. until early morning. It includes a diverse range of sectors such as entertainment, dining, hospitality, and nightlife, with establishments such as bars, clubs, restaurants, theaters, and live music venues playing a significant role. The development of the night-time economy refers to the process of managing and promoting the growth of economic activities during the evening and night hours in a manner that balances economic, social, and environmental considerations. Therefore, the paper aimed to identify the factors affecting the night-time economy in Hanoi to achieve the sustainable development of this economy. The paper processed and analyzed the data using SPSS Statistics 26.0 software. The quantitative study included (1) testing the suitability of the scale for the variables using Cronbach's alpha, (2) analyzing the EFA factors to check the convergence of the observed variables and the separation between the independent variables, (3) checking the correlation to evaluate the problem of multicollinearity of the model, and (4) performing regression analysis to evaluate the impact of the factors on night-time economic development in Hanoi City. The empirical results showed that the variables positively impacted night-time economic development in Hanoi. However, the study found differences in the levels of their impact. Among the four factors, factor 3 (promotion and sharing) had the strongest impact on night-time economic development, followed by factor 2 (city infrastructure and safety), factor 1 (institutions and environment), and factor 4 (nature and resources). The empirical results will help policymakers promote the sustained development of the night-time economy in Hanoi, Vietnam. [ABSTRACT FROM AUTHOR]