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157 results on '"Somme, Stig"'

2. Management of Gastroschisis: Timing of Delivery, Antibiotic Usage, and Closure Considerations (A Systematic Review From the American Pediatric Surgical Association Outcomes & Evidence Based Practice Committee)

Author

Slidell, Mark B., McAteer, Jarod, Miniati, Doug, Sømme, Stig, Wakeman, Derek, Rialon, Kristy, Lucas, Don, Beres, Alana, Chang, Henry, Englum, Brian, Kawaguchi, Akemi, Gonzalez, Katherine, Speck, Elizabeth, Villalona, Gustavo, Kulaylat, Afif, Rentea, Rebecca, Yousef, Yasmine, Darderian, Sarkis, Acker, Shannon, St Peter, Shawn, Kelley-Quon, Lorraine, Baird, Robert, and Baerg, Joanne

Published
2024
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3. Evaluation and Management of Primary Spontaneous Pneumothorax in Adolescents and Young Adults: A Systematic Review From the APSA Outcomes & Evidence-Based Practice Committee

Author

Speck, K. Elizabeth, Kulaylat, Afif N., Baerg, Joanne E., Acker, Shannon N., Baird, Robert, Beres, Alana L., Chang, Henry, Derderian, S. Christopher, Englum, Brian, Gonzalez, Katherine W., Kawaguchi, Akemi, Kelley-Quon, Lorraine, Levene, Tamar L., Rentea, Rebecca M., Rialon, Kristy L., Ricca, Robert, Somme, Stig, Wakeman, Derek, Yousef, Yasmine, St. Peter, Shawn D., and Lucas, Donald J.

Published
2023
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4. Management of the undescended testis in children: An American Pediatric Surgical Association Outcomes and Evidence Based Practice Committee Systematic Review

Author

Gates, Robert L, Shelton, Julia, Diefenbach, Karen A, Arnold, Meghan, St. Peter, Shawn D., Renaud, Elizabeth J., Slidell, Mark B., Sømme, Stig, Valusek, Patricia, Villalona, Gustavo A., McAteer, Jarod P., Beres, Alana L., Baerg, Joanne, Rentea, Rebecca M., Kelley-Quon, Lorraine, Kawaguchi, Akemi L., Hu, Yue-Yung, Miniati, Doug, Ricca, Robert, and Baird, Robert

Published
2022
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6. Management and outcomes for long-segment Hirschsprung disease: A systematic review from the APSA Outcomes and Evidence Based Practice Committee

Author

Kawaguchi, Akemi L., Guner, Yigit S., Sømme, Stig, Quesenberry, Alexandria C., Arthur, L. Grier, Sola, Juan E., Downard, Cynthia D., Rentea, Rebecca M., Valusek, Patricia A., Smith, Caitlin A., Slidell, Mark B., Ricca, Robert L., Dasgupta, Roshni, Renaud, Elizabeth, Miniati, Doug, McAteer, Jarod, Beres, Alana L., Grabowski, Julia, Peter, Shawn D.St., and Gosain, Ankush

Published
2021
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7. The effects of early anesthesia on neurodevelopment: A systematic review

Author

Grabowski, Julia, Goldin, Adam, Arthur, L. Grier, Beres, Alana L., Guner, Yigit S., Hu, Yue-Yung, Kawaguchi, Akemi L., Kelley-Quon, Lorraine I., McAteer, Jarod P., Miniati, Doug, Renaud, Elizabeth J., Ricca, Robert, Slidell, Mark B., Smith, Caitlin A., Sola, Juan E., Sømme, Stig, Downard, Cynthia D., Gosain, Ankush, Valusek, Patricia, St. Peter, Shawn D., Jagannathan, Narasimhan ‘Sim’, and Dasgupta, Roshni

Published
2021
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8. Management of intussusception in children: A systematic review

Author

Kelley-Quon, Lorraine I., Arthur, L. Grier, Williams, Regan F., Goldin, Adam B., St. Peter, Shawn D., Beres, Alana L., Hu, Yue-Yung, Renaud, Elizabeth J., Ricca, Robert, Slidell, Mark B., Taylor, Amy, Smith, Caitlin A., Miniati, Doug, Sola, Juan E., Valusek, Patricia, Berman, Loren, Raval, Mehul V., Gosain, Ankush, Dellinger, Matthew B., Sømme, Stig, Downard, Cynthia D., McAteer, Jarod P., and Kawaguchi, Akemi

Published
2021
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9. Omphalocele

Author

Sømme, Stig, Langer, Jacob C., Lumley, J.S.P., Series Editor, Howe, James R., Series Editor, Puri, Prem, editor, and Höllwarth, Michael E., editor

Published
2019
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13. Omphalocele

Author

Somme, Stig, Langer, Jacob C., Lumley, J. S. P., editor, Siewert, J. R., editor, Puri, Prem, editor, and Höllwarth, Michael E., editor

Published
2006
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23. Vascular and pulmonary comorbidities in children with congenital EA/TEF

Author

Poore, Thomas S., primary, Weinman, Jason P., additional, Handley, Elyse, additional, Wine, Todd, additional, Helland, Sparrow, additional, Corbett, Benjamin, additional, Antoniolli, Natalie, additional, Somme, Stig, additional, Friedlander, Joel, additional, Prager, Jeremy D, additional, and DeBoer, Emily M., additional

Published
2020
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24. Contributors

Author

Alonso, Maria H., primary, Azizkhan, Richard G., additional, Baregamian, Naira, additional, Beierle, Elizabeth A., additional, Billmire, Deborah F., additional, Brandt, Mary L., additional, Chen, Mike K., additional, Chung, Dai H., additional, Davidoff, Andrew M., additional, Dicken, Bryan J., additional, Dickie, Belinda Hsi, additional, Falcone, Richard A., additional, Fallat, Mary E., additional, Frischer, Jason S., additional, Gatti, John M., additional, Goretsky, Michael J., additional, Hines, Michael H., additional, Hirschl, Ronald B., additional, Inge, Thomas H., additional, Islam, Saleem, additional, Josephs, Michael D., additional, Kane, Timothy D., additional, Kawaguchi, Akemi L., additional, Kim, Anne C., additional, Kim, Eugene S., additional, Kuenzler, Keith A., additional, Langer, Jacob C., additional, Levitt, Marc, additional, Manning, Peter B., additional, Meyer, Tory A., additional, Mortellaro, Vincent, additional, Murphy, J. Patrick, additional, Nathan, Jaimie D., additional, Nuss, Donald, additional, Ostlie, Daniel J., additional, Peña, Alberto, additional, Pranikoff, Thomas, additional, Rescorla, Frederick J., additional, Reynolds, Marleta, additional, Ricketts, Richard, additional, Ryckman, Frederick C., additional, Segura, Bradley J., additional, Shamberger, Robert C., additional, Somme, Stig, additional, St. Peter, Shawn D., additional, Stolar, Charles J.H., additional, Teitelbaum, Daniel H., additional, Tiao, Greg M., additional, von Allmen, Daniel, additional, Warner, Brad W., additional, and Wulkan, Mark L., additional

Published
2010
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31. Non-operative management of solid organ injuries in children: An American Pediatric Surgical Association Outcomes and Evidence Based Practice Committee systematic review

Author

Gates, Robert L., primary, Price, Mitchell, additional, Cameron, Danielle B., additional, Somme, Stig, additional, Ricca, Robert, additional, Oyetunji, Tolulope A., additional, Guner, Yigit S., additional, Gosain, Ankush, additional, Baird, Robert, additional, Lal, Dave R., additional, Jancelewicz, Tim, additional, Shelton, Julia, additional, Diefenbach, Karen A., additional, Grabowski, Julia, additional, Kawaguchi, Akemi, additional, Dasgupta, Roshni, additional, Downard, Cynthia, additional, Goldin, Adam, additional, Petty, John K., additional, Stylianos, Steven, additional, and Williams, Regan, additional

Published
2019
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36. Cover Image

Author

Masaracchia, Melissa M., primary, Polaner, David M., additional, Prager, Jeremy D., additional, DeBoer, Emily M., additional, Dewberry, Lindel C., additional, Somme, Stig, additional, Wine, Todd, additional, and Janosy, Norah R., additional

Published
2018
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38. Ovarian torsion in pediatric and adolescent patients: A systematic review

Author

Dasgupta, Roshni, primary, Renaud, Elizabeth, additional, Goldin, Adam B., additional, Baird, Robert, additional, Cameron, Danielle B., additional, Arnold, Meghan A., additional, Diefenbach, Karen A., additional, Gosain, Ankush, additional, Grabowski, Julia, additional, Guner, Yigit S., additional, Jancelewicz, Tim, additional, Kawaguchi, Akemi, additional, Lal, Dave R., additional, Oyetunji, Tolulope A, additional, Ricca, Robert L., additional, Shelton, Julia, additional, Somme, Stig, additional, Williams, Regan F, additional, and Downard, Cynthia D., additional

Published
2018
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40. Pharmacokinetic and Pharmacodynamic Properties of Metronidazole in Pediatric Patients With Acute Appendicitis: A Prospective Study.

Author

Child, Jason, Chen, Xinhui, Mistry, Rakesh D, Somme, Stig, MacBrayne, Christine, Anderson, Peter L, Jones, Ronald N, and Parker, Sarah K

Subjects
APPENDICITIS, BACTEROIDES, LIQUID chromatography, LONGITUDINAL method, MASS spectrometry, METRONIDAZOLE, PEDIATRICS, PHARMACODYNAMICS
Abstract

Background Metronidazole is traditionally dosed every 6–8 hours even though in adults it has a long half-life, concentration-dependent killing, and 3-hour postantibiotic effect. Based on this logic, some pediatric hospitals adopted once-daily dosing for appendicitis, despite limited pharmacokinetics-pharmacodynamics (PK/PD) in children. We studied pediatric patients with appendicitis given metronidazole once daily to determine whether this dosing would meet target area under the curve (AUC)/minimum inhibitory concentration (MIC) ratio of ≥70 for Bacteroides fragilis. Methods One hundred pediatric patients aged 4–17 years had an average of 3 blood draws per patient during the first 24 hours after a 30 mg/kg per dose of intravenous metronidazole. Concentrations of drug were determined using validated liquid chromatography and tandem mass spectrometry. A NONMEM model was constructed for determining PK, followed by Monte Carlo simulations to generate a population of plasma concentration-time AUC of metronidazole and hydroxy-metronidazole. Results Simulated AUC values met target attainment (AUC/MIC ratio of ≥70 to B fragilis MICs) for 96%–100% of all patients for an MIC of 2 mcg/mL. For MICs of 4 and 8 mcg/mL, target attainment ranged from 61% to 97% and 9% to 71%, respectively. Areas under the curve were similar to that of adults receiving 1000 mg and 1500 mg q24, or 500 mg q8 hours. Conclusions Metronidazole, 30 mg/kg per dose, once daily achieved AUC target attainment for B fragilis with an MIC of 2 mcg/mL or less in pediatric appendicitis patients. Based on this and studies in adults, there does not seem to be any PK/PD advantage of more frequent dosing in this population. [ABSTRACT FROM AUTHOR]

Published
2019
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41. Colaboradores

Author

Acker, Shannon N., Adams, Megan, Albuja-Cruz, Maria B., Alexander, Jason Q., Anderson, Benjamin O., Arron, Sarah Tuttleton, Bak, Thomas, Barnett, Carlton C., Jr., Baxter, Bernard Timothy, Beauchamp, Kathryn, Bhuket, Taft, Biffl, Walter L., Bir, Natasha D., Bischoff, Andrea, Blaschko, Sarah D., Brakenridge, Scott C., Bredbeck, Brooke C., Brew, Elizabeth C., Brinckerhoff, Laurence H., Brooke, Magdalene A., Brown, Elizabeth E., Brown, James M., Bruny, Jennifer L., Bui, Eric, Bullard, M. Kelley, Burlew, Clay Cothren, Calhoun, Kristine E., Campion, Eric M., Capek, Karel D., Chapman, John, Choi, Chun W., Chomsky-Higgins, Kathryn H., Ciesla, David J., Cleveland, Joseph C., Jr., Crandall, Marie, Croft, Chasen A., Crombleholme, Timothy M., Cushman, James, Davis, Stephanie N., Donalisio da Silva, Rodrigo, Eun, John C., Evans, Chadrick R., Finlayson, Christina A., Foley, Lisa S., Fox, Charles J., Freese, Krister, Fullerton, David A., Geelhoed, Glenn W., Graf, Jahanara, Green, Amanda J., Ha, Richard-Tien V., Haenel, James B., Hak, David J., Hamm, Aidan D., Harken, Alden H., Harken, Tabetha R., Herndon, David N., Hurt, Brian, Imhoff, Laurel R., Indresano, A. Thomas, Ipaktchi, Kyros, Ito, Timothy K., Jamaleddine, Ghassan, Johnson, Jeffrey L., Jones, Edward L., Kim, Fernando J., Kulungowski, Ann M., Kumar, Ramesh M., LaFace, Angela R., Lawless, Ryan A., Lepore, Michael L., Liscum, Kathleen R., Liu, Benny, Liu, Jeffrey C., Lo, Karen K., Lu, Ning, Malliaris, Stephanie D., Mathes, David W., McCarter, Martin D., McIntyre, Robert C., Jr., McKenna, Logan R., Meldrum, Daniel R., Miraflor, Emily, Moore, Ernest E., Moore, Hunter B., Moore, Peter K., Moore, Scott M., Morgan, Ashley Eleen, Nguyen, Tony, Nydam, Trevor L., Oottamasathien, Siam, Overbey, Douglas M., Palmer, Barnard J.A., Park, Chan M., Partrick, David A., Pearlman, Nathan W., Peltz, Eric D., Peña, Alberto, Pessoa, Rodrigo, Pshak, Thomas, Raeburn, Christopher D., Reece, T. Brett, Rehring, Thomas F., Ridge, John A., Roach, Jonathan P., Robinson, Thomas N., Rosenthal, Martin D., Selzman, Craig, Shackford, Steven R., Shook, Erica, Skarupa, David J., Sømme, Stig, Stahel, Philip F., Suh, Melissa K., Swanson, John M., Swift, U. Mini B., Tello, Tiffany L., Tessler, Robert A., Torphy, Robert J., VanderHeiden, Todd F., Vanzant, Erin L., Victorino, Gregory P., Werahera, Priya N., Williams, Jessica L., Wong, Robert, Yamaguchi, Yuka, and Zanotti, Giorgio

Published
2019
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45. Contributors

Author

Acker, Shannon N., Adams, Megan, Albuja-Cruz, Maria B., Alexander, Jason Q., Anderson, Benjamin O., Arron, Sarah Tuttleton, Bak, Thomas, Barnett, Carlton C., Jr., Baxter, Bernard Timothy, Beauchamp, Kathryn, Bhuket, Taft, Biffl, Walter L., Bir, Natasha D., Bischoff, Andrea, Blaschko, Sarah D., Brakenridge, Scott C., Bredbeck, Brooke C., Brew, Elizabeth C., Brinckerhoff, Laurence H., Brooke, Magdalene A., Brown, Elizabeth E., Brown, James M., Bruny, Jennifer L., Bui, Eric, Bullard, M. Kelley, Burlew, Clay Cothren, Calhoun, Kristine E., Campion, Eric M., Capek, Karel D., Chapman, John, Choi, Chun W., Chomsky-Higgins, Kathryn H., Ciesla, David J., Cleveland, Joseph C., Jr., Crandall, Marie, Croft, Chasen A., Crombleholme, Timothy M., Cushman, James, Davis, Stephanie N., Donalisio da Silva, Rodrigo, Eun, John C., Evans, Chadrick R., Finlayson, Christina A., Foley, Lisa S., Fox, Charles J., Freese, Krister, Fullerton, David A., Geelhoed, Glenn W., Graf, Jahanara, Green, Amanda J., Ha, Richard-Tien V., Haenel, James B., Hak, David J., Hamm, Aidan D., Harken, Alden H., Harken, Tabetha R., Herndon, David N., Hurt, Brian, Imhoff, Laurel R., Indresano, A. Thomas, Ipaktchi, Kyros, Ito, Timothy K., Jamaleddine, Ghassan, Johnson, Jeffrey L., Jones, Edward L., Kim, Fernando J., Kulungowski, Ann M., Kumar, Ramesh M., LaFace, Angela R., Lawless, Ryan A., Lepore, Michael L., Liscum, Kathleen R., Liu, Benny, Liu, Jeffrey C., Lo, Karen K., Lu, Ning, Malliaris, Stephanie D., Mathes, David W., McCarter, Martin D., McIntyre, Robert C., Jr., McKenna, Logan R., Meldrum, Daniel R., Miraflor, Emily, Moore, Ernest E., Moore, Hunter B., Moore, Peter K., Moore, Scott M., Morgan, Ashley Eleen, Nguyen, Tony, Nydam, Trevor L., Oottamasathien, Siam, Overbey, Douglas M., Palmer, Barnard J.A., Park, Chan M., Partrick, David A., Pearlman, Nathan W., Peltz, Eric D., Peña, Alberto, Pessoa, Rodrigo, Pshak, Thomas, Raeburn, Christopher D., Reece, T. Brett, Rehring, Thomas F., Ridge, John A., Roach, Jonathan P., Robinson, Thomas N., Rosenthal, Martin D., Selzman, Craig, Shackford, Steven R., Shook, Erica, Skarupa, David J., Sømme, Stig, Stahel, Philip F., Suh, Melissa K., Swanson, John M., Swift, U. Mini B., Tello, Tiffany L., Tessler, Robert A., Torphy, Robert J., VanderHeiden, Todd F., Vanzant, Erin L., Victorino, Gregory P., Werahera, Priya N., Williams, Jessica L., Wong, Robert, Yamaguchi, Yuka, and Zanotti, Giorgio

Published
2018
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