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Popular tree Neem (Azadirachta indica) is a member of the Meliaceae family. Many foods are prepared using bark, leaves, flowers, seeds, oil, and other materials in the Traditional System of Medicine. For pharmaceutical uses, neem has been the subject of several patent applications. The pharmacognosy, phytochemistry, and pharmacological activities that have been documented thus far are all thoroughly examined in this review. As a source of several therapeutic substances in Indian culture and a plant that thrives in tropical and semi-tropical regions, neem is the most beneficial traditional medicine. All parts of the neem tree--bark, leaves, fruits, seeds, and extracts--are utilized in traditional medicine. Its extracts are anti-inflammatory, anti-viral, antibacterial, anti-fungal, anthelmintic, and anti-allergic. The names "free tree of India," "wonder tree," "Nature's drug store," "Village dispensary," "Divine tree," "heal all," and "Panacea of all Diseases" are also used to neem. In current times, non-toxic herbal items should be used with specific concentration to control animal and human ailments. There is much room for this amazing plant to be used more effectively. [ABSTRACT FROM AUTHOR]

A accessible ultramodern life brings along with it a host of problems including acidity and Gastrointestinal issues. Poor eating habits, racy food and guzzling too numerous carbonated drinks Disrupts the pH balance and natural foliage of the stomach causing both bloating and acidity making Antacids the most common tone- specified specifics available over the counter. Common Dental Procedures and oral conditions requires dentists to define NSAIDs and antibiotics which alleviates Acidity. The antacids act by negativing the acid in the stomach and by inhibiting pepsin, which is a proteolytic enzyme. Each of These cationic mariners has a characteristic pharmacological property that determines its clinical use. In recent times, demands of identification and evaluation of new medicines conceivably of factory origin are gaining fashionability for the treatment of colorful gastrointestinal conditions. Hence, herbal drugs were considered a better cover for the treatment of acid influx/acidity with lower adverse side goods. The main ideal of the study was to elect sauces which were used as a home -- remedy having parcels for negativing the Acid of the stomach viz Cumin( Cuminum cyminum), Sprague (Trachyspermum ammi), and Peppermint (Mentha piperita) and incorporate in their excerpt forms in dividually into the new expression( Bouncy grains) developed by using wet granulation Method. Antacids are generally recommended for grown-ups and children at least 12 times old, and the FDA recommends antacids as the first-line treatment for heartburn in gestation. Herbal antacids are also one of the major classes of over the Counter drugs used by patient considering its safety. Hence, in present Study we attempted to prepare two formulations, one is aluminium Hydroxide suspension and second is combination of calcium carbonate and magnesium oxide suspension aswell as compares this by marketed Formulation through antacid activity using in vitro methods viz-acid-Neutralizing capacity and buffering capacity. [ABSTRACT FROM AUTHOR]

The utilization of medications to treat illness is entering a new phase in which an increasing variety of cutting-edge drug delivery techniques are being used. The oral mucosa has a number of characteristics that make it an appealing location for drug administration but also present a number of challenges for researchers in terms of effective and efficient therapeutic active agent delivery. Nevertheless, a number of obstacles were solved with the invention of novel distribution strategies. High blood flow, quick recovery, avoiding the hepatic first-pass impact, and pre-systemic elimination in the gastrointestinal tract are just a few benefits of oral mucosa delivery. However, the main drawbacks of buccal delivery include its relatively small surface area and considerable drug loss from swallowing and salivary flow. For distribution into and/or across the oral mucosa, a variety of formulations, including sprays, pills, mouthwashes, gels, pastes, and patches, are now employed. Numerous formulations for buccal drug delivery systems have been created over the past 20 years, but only a few number have proven successful enough to be approved as medicines. The absence of standardized methodologies to assess the in vitro effectiveness of buccal dosage forms may be one of the primary causes of this poor outcome. The purpose of this study is to explain the advantages of buccal dosage forms and buccal drug delivery, as well as to examine current research and in vitro analysis techniques for buccal dosage forms. [ABSTRACT FROM AUTHOR]