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3. International virtual confidential reviews of infection-related maternal deaths and near-miss in 11 low- and middle-income countries – case report series and suggested actions

Author

Okafor, Obiageli, Roos, Nathalie, Abdosh, Abdulfetah Abdulkadir, Adesina, Olubukola, Alaoui, Zaynab, Romero, William Arriaga, Assarag, Bouchra, Aworinde, Olufemi, de Bernis, Luc, Castro, Rigoberto, Chrifi, Hassan, Day, Louise Tina, Demissew, Rahel, Aceituno, María Guadalupe Flores, Gadama, Luis, Gashawbeza, Biruck, Keke, Sourou Goufodji, Govule, Philip, Gwako, George, Jayaratne, Kapila, Komboigo, Evelyne Béwendin, Lara, Bredy, Madziyire, Mugove Gerald, Mathai, Matthews, Moulki, Rachid, Moutaouadia, Iatimad, Munjanja, Stephen, Fletes, Carlos Alberto Ochoa, Ortiz, Edgar Ivan, Ouedraogo, Henri Gautier, Qureshi, Zahida, Recidoro, Zenaida Dy, Senanayake, Hemantha, Soma-Pillay, Priya, Tin, Khaing Nwe, Sedami, Pascal, Worku, Dawit, and Bonet, Mercedes

Published
2022
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4. FIGO good practice recommendations on optimizing models of care for the prevention and mitigation of preterm birth.

Author

Anumba, Dilly, Soma‐Pillay, Priya, Bianchi, Ana, Valencia González, Catalina M., Jacobbson, Bo, Valencia González, Catalina M., Gudu, Wondimu, Jacobsson, Bo, Lozada, Nancy Sierra, Ojeda, Leticia, Patel, Madhuri, Shennan, Andrew, Rigoni, Rodrigo, Suplido, Sherri Ann, Daneva, Ana, Wanyonyi, Sikolia, and Abenhaim, Haim

Subjects
*PREMATURE labor, *MEDICAL personnel, *MATERNAL health services, *CONTINUUM of care, *SECONDARY care (Medicine), *PRECONCEPTION care
Abstract

The global challenge of preterm birth persists with little or no progress being made to reduce its prevalence or mitigate its consequences, especially in low‐resource settings where health systems are less well developed. Improved delivery of respectful person‐centered care employing effective care models delivered by skilled healthcare professionals is essential for addressing these needs. These FIGO good practice recommendations provide an overview of the evidence regarding the effectiveness of the various care models for preventing and managing preterm birth across global contexts. We also highlight that continuity of care within existing, context‐appropriate care models (such as midwifery‐led care and group care), in primary as well as secondary care, is pivotal to delivering high quality care across the pregnancy continuum—prior to conception, through pregnancy and birth, and preparation for a subsequent pregnancy—to improve care to prevent and manage preterm birth. Synopsis: To mitigate preterm birth and its consequences, maternity models of care in all contexts should prioritize consistency and continuity of care and carer(s). [ABSTRACT FROM AUTHOR]

Published
2024
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5. Gestation-dependent increase in cervicovaginal pro-inflammatory cytokines and cervical extracellular matrix proteins is associated with spontaneous preterm delivery within 2 weeks of index assessment in South African women.

Author

Amabebe, Emmanuel, Ikumi, Nadia, Oosthuizen, Ally, Soma-Pillay, Priya, Matjila, Mushi, and Anumba, Dilly O. C.

Subjects
EXTRACELLULAR matrix proteins, SOUTH Africans, PREMATURE labor, TISSUE remodeling, MATRIX metalloproteinases
Abstract

Introduction: Inflammation-induced remodelling of gestational tissues that underpins spontaneous preterm birth (sPTB, delivery < 37 weeks' gestation) may vary by race and context. To explore relationships between markers of these pathological processes, we (a) characterised the cervicovaginal fluid (CVF) cytokine profiles of pregnant South African women at risk of PTB; (b) determined CVF matrix-metalloproteinase-9 (MMP-9) and its regulator tissue inhibitor of metalloproteinase-1 (TIMP-1); and (c) explored the predictive potential of these markers for sPTB. Method of study: The concentrations of 10 inflammatory cytokines and MMP-9 and TIMP-1 were determined by ELISA in CVF samples from 47 non-labouring women at high risk of PTB. We studied CVF sampled at three gestational time points (GTPs): GTP1 (20-22 weeks, n = 37), GTP2 (26-28 weeks, n = 40), and GTP3 (34-36 weeks, n = 29) and analysed for changes in protein concentrations and predictive capacities (area under the ROC curve (AUC) and 95% confidence interval (CI)) for sPTB. Results: There were 11 (GTP1), 13 (GTP2), and 6 (GTP3) women who delivered preterm within 85.3 ± 25.9, 51.3 ± 15.3, and 11.8 ± 7.5 (mean ± SD) days after assessment, respectively. At GTP1, IL-8 was higher (4-fold, p = 0.02), whereas GM-CSF was lower (~1.4-fold, p = 0.03) in the preterm compared with term women with an average AUC = 0.73. At GTP2, IL-1β (18-fold, p < 0.0001), IL-8 (4-fold, p = 0.03), MMP-9 (17-fold, p = 0.0007), MMP-9/TIMP-1 ratio (9-fold, p = 0.004), and MMP-9/GM-CSF ratio (87-fold, p = 0.005) were higher in preterm compared with term women with an average AUC = 0.80. By contrast, IL-10 was associated with term delivery with an AUC (95% CI) = 0.75 (0.55-0.90). At GTP3, IL-1β (58-fold, p = 0.0003), IL-8 (12-fold, p = 0.002), MMP-9 (296-fold, p = 0.03), and TIMP-1 (35-fold, p = 0.01) were higher in preterm compared with term women with an average AUC = 0.85. Elevated IL-1β was associated with delivery within 14 days of assessment with AUC = 0.85 (0.67-0.96). Overall, elevated MMP-9 at GTP3 had the highest (13.3) positive likelihood ratio for distinguishing women at risk of sPTB. Lastly, a positive correlation between MMP-9 and TIMP-1 at all GTPs (r = 0.61, p < 0.01) for women delivering at term was only observed at GTP1 for those who delivered preterm (r = 0.70, p < 0.03). Conclusions: In this cohort, sPTB is associated with gestation-dependent increase in pro-inflammatory cytokines, decreased IL-10 and GM-CSF, and dysregulated MMP-9-TIMP-1 interaction. Levels of cytokine (especially IL-1β) and ECM remodelling proteins rise significantly in the final 2 weeks before the onset of labour when sPTB is imminent. The signalling mechanisms for these ECM remodelling observations remain to be elucidated. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Availability of facility resources and services and infection-related maternal outcomes in the WHO Global Maternal Sepsis Study: a cross-sectional study

Author

Brizuela, Vanessa, Cuesta, Cristina, Bartolelli, Gino, Abdosh, Abdulfetah Abdulkadir, Abou Malham, Sabina, Assarag, Bouchra, Castro, Rigoberto, Díaz, Virginia, El Kak, Faysal, Elsheikh, Mohamed, Pérez, Aquilino M., Souza, João Paulo, Bonet, Mercedes, Abalos, Edgardo, Aman, Mohammad Iqbal, Noormal, Bashir, Espinoza, Marisa, Pasquale, Julia, Leroy, Charlotte, Roelens, Kristien, Vandenberghe, Griet, Agossou, M. Christian Urlyss, Goufodji Keke, Sourou, Tshabu Aguemon, Christiane, Apaza Peralta, Patricia Soledad, Conde Altamirano, Víctor, Hernández Muñoz, Rosalinda, Cecatti, José Guilherme, Ribeiro do Valle, Carolina, Batiene, Vincent, Cisse, Kadari, Ouedraogo, Henri Gautier, Cheang, Kannitha, Lam, Phirun, Rathavy, Tung, Simo, Elie, Tebeu, Pierre-Marie, Yakana, Emah Irene, Carvajal, Javier, Escobar, María Fernanda, Fernández, Paula, Colmorn, Lotte Berdiin, Langhoff-Roos, Jens, Mereci, Wilson, Vélez, Paola, Salah Eldin, Yasser, Sultan, Alaa, Teklu, Alula M., Worku, Dawit, Adanu, Richard, Govule, Philip, Noora Lwanga, Charles, Arriaga Romero, William Enrique, Flores Aceituno, María Guadalupe, Bustillo, Carolina, Lara, Bredy, Kumar, Vijay, Suri, Vanita, Trikha, Sonia, Cetin, Irene, Donati, Serena, Personeni, Carlo, Baimussanova, Guldana, Kabylova, Saule, Sagyndykova, Balgyn, Gwako, George, Osoti, Alfred, Qureshi, Zahida, Asylbasheva, Raisa, Boobekova, Aigul, Seksenbaeva, Damira, Itani, Saad Eddine, Minkauskienė, Meilė, Ramašauskaitė, Diana, Chikhwaza, Owen, Gadama, Luis, Malunga, Eddie, Dembele, Haoua, Sangho, Hamadoun, Zerbo, Fanta Eliane, Dávila Serapio, Filiberto, Herrera Maldonado, Nazarea, Islas Castañeda, Juan I., Cauaus, Tatiana, Curteanu, Ala, Petrov, Victor, Buyanjargal, Yadamsuren, Khishgee, Seded, Lkhagvasuren, Bat-Erdene, Essolbi, Amina, Moulki, Rachid, Jaze, Zara, Mariano, Arlete, Bique Osman, Nafissa, Einda, Hla Mya Thway, Maung, Thae Maung, Tin, Khaing Nwe, Gurung, Tara, Shrestha, Amir Babu, Shrestha, Sangeeta, Bloemenkamp, Kitty, Rijken, Marcus J., Van Den Akker, Thomas, Estrada, María Esther, Pavón Gómez, Néstor J., Adesina, Olubukola, Aimakhu, Chris, Fawole, Bukola, Chaudhri, Rizwana, Hamid, Saima, Khan, M. Adnan, Huatuco Hernández, María del Pilar, Zavaleta Pimentel, Nelly M., Andal, Maria Lu, Recidoro, Zenaida Dy, Martin, Carolina Paula, Budianu, Mihaela, Puşcaşiu, Lucian, Diouf, Léopold, Guirassy, Dembo, Moreira, Philippe Marc, Borovsky, Miroslav, Kovac, Ladislav, Kristufkova, Alexandra, Cebekhulu, Sylvia, Cornelissen, Laura, Soma-Pillay, Priya, Cararach, Vicenç, López, Marta, Vidal Benedé, María José, Jayakody, Hemali, Jayaratne, Kapila, Rowel, Dhammica, Nabag, Wisal, Omer, Sara, Tsoy, Victoria, Uzakova, Urunbish, Yunusova, Dilrabo, Siriwachirachai, Thitiporn, Tangsiriwatthana, Thumwadee, Dunlop, Catherine, Knight, Marian, Lissauer, David, Roman, Jhon, Vitureira, Gerardo, Tuan, Dinh Anh, Truong, Luong Ngoc, Hanh, Nghiem Thi Xuan, Madziyire, Mugove, Magwali, Thulani, Munjanja, Stephen, Baguiya, Adama, Chamillard, Mónica, Kouanda, Seni, Lumbiganon, Pisake, Nabhan, Ashraf, Nadisauskiene, Ruta, Bartlett, Linda, Bellissimo-Rodrigues, Fernando, Jacob, Shevin T., Shakoor, Sadia, Yunis, Khalid, Campodónico, Liana, Gamerro, Hugo, Giordano, Daniel, Althabe, Fernando, Gülmezoglu, A. Metin, Castro Banegas, Rigoberto, El-Kak, Faysal, El Sheikh, Mohamed, and Pérez, Aquilino M

Published
2021
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9. Frequency and management of maternal infection in health facilities in 52 countries (GLOSS): a 1-week inception cohort study

Author

Bonet, Mercedes, Brizuela, Vanessa, Abalos, Edgardo, Cuesta, Cristina, Baguiya, Adama, Chamillard, Mónica, Fawole, Bukola, Knight, Marian, Kouanda, Seni, Lumbiganon, Pisake, Nabhan, Ashraf, Nadisauskiene, Ruta J, Abdulkadir, Abdulfetah, Adanu, Richard MK, Aman, Mohammad Iqbal, Arriaga Romero, William E., Assarag, Bouchra, Bloemenkamp, Kitty W.M., Boobekova, Aigul, Budianu, Mihaela A., Cararach, Vicenç, Castro, Rigoberto, Cebekhulu, Sylvia, Cecatti, José Guilherme, Colmorn, Lotte Berdiin, Curteanu, Ala, Donati, Serena, Einda, Hla Mya Thway, El Deen, Yasser Salah, El Kak, Faysal, Elsheikh, Mohamed, Escobar-Vidarte, Maria F, Espinoza, Marisa Mabel, Estrada, María Ester, Gadama, Luis Aaron, Goufodji, Sourou B, Hamid, Saima, Hernandez Munoz, Rosalinda, Herrera Maldonado, Nazarea, Jayaratne, Kapila, Kabylova, Saule, Kristufkova, Alexandra, Kumar, Vijay, Lissauer, David, Mereci, Wilson, Minkauskiene, Meile, Moreira, Philippe, Munjanja, Stephen, B. Osman, Nafissa, Ouedraogo, Henri Gautier, Perez, Aquilino M., Pasquale, Julia, Puscasiu, Lucian, Qureshi, Zahida, Recidoro, Zenaida, C. Ribeiro-do-Valle, Carolina, Rowel, Dhammica, Sangho, Hamadoun, Shrestha, Amir Babu, Siriwachirachai, Thitiporn, Tebeu, Pierre Marie, Tin, Khaing Nwe, Tuan, Dinh Anh, Tung, Rathavy, Vandenberghe, Griet, Yadamsuren, Buyanjargal, Yunusova, Dilrabo, Zavaleta Pimentel, Nelly, Noormal, Bashir, Díaz, Virginia, Leroy, Charlotte, Roelens, Kristien, Agossou, M. Christian Urlyss, Tshabu Aguemon, Christiane, Apaza Peralta, Patricia Soledad, Conde Altamirano, Víctor, Batiene, Vincent, Cisse, Kadari, Cheang, Kannitha, Lam, Phirun, Simo, Elie, Yakana, Emah Irene, Carvajal, Javier, Fernández, Paula, Langhoff-Roos, Jens, Vélez, Paola, Sultan, Alaa, Teklu, Alula M., Worku, Dawit, Govule, Philip, Noora Lwanga, Charles, Flores Aceituno, María Guadalupe, Bustillo, Carolina, Lara, Bredy, Suri, Vanita, Trikha, Sonia, Cetin, Irene, Personeni, Carlo, Baimussanova, Guldana, Sagyndykova, Balgyn, Gwako, George, Osoti, Alfred, Asylbasheva, Raisa, Seksenbaeva, Damira, Itani, Saad Eddine, Abou Malham, Sabina, Ramašauskaitė, Diana, Chikhwaza, Owen, Malunga, Eddie, Dembele, Haoua, Zerbo, Fanta Eliane, Dávila Serapio, Filiberto, Islas Castañeda, Juan I., Cauaus, Tatiana, Petrov, Victor, Khishgee, Seded, Lkhagvasuren, Bat-Erdene, Essolbi, Amina, Moulki, Rachid, Jaze, Zara, Mariano, Arlete, Maung, Thae Maung, Gurung, Tara, Shrestha, Sangeeta, Rijken, Marcus J., Van Den Akker, Thomas, Estrada, María Esther, Pavón Gómez, Néstor J., Adesina, Olubukola, Aimakhu, Chris, Chaudhri, Rizwana, Khan, M. Adnan, Huatuco Hernández, María del Pilar, Andal, Maria Lu, Martin, Carolina Paula, Diouf, Léopold, Guirassy, Dembo, Borovsky, Miroslav, Kovac, Ladislav, Cornelissen, Laura, Soma-Pillay, Priya, López, Marta, Vidal Benedé, María José, Jayakody, Hemali, Nabag, Wisal, Omer, Sara, Tsoy, Victoria, Uzakova, Urunbish, Tangsiriwatthana, Thumwadee, Dunlop, Catherine, Roman, Jhon, Vitureira, Gerardo, Truong, Luong Ngoc, Hanh, Nghiem Thi Xuan, Madziyire, Mugove, Magwali, Thulani, Bartlett, Linda, Bellissimo-Rodrigues, Fernando, Jacob, Shevin T., Shakoor, Sadia, Yunis, Khalid, Campodónico, Liana, Gamerro, Hugo, Giordano, Daniel, Althabe, Fernando, Gülmezoglu, A. Metin, and Souza, João Paulo

Published
2020
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11. List of Contributors

Author

Ali, Sulafa K.M., primary, Antunes, Manuel J., additional, Baker, Michael G., additional, Bansal, Raghav, additional, Beaton, Andrea, additional, Carapetis, Jonathan, additional, Cilliers, Antoinette, additional, Coutinho, Gonçalo F., additional, Cunningham, Madeleine, additional, de Dassel, Jessica L., additional, Dougherty, Scott, additional, Engel, Mark E., additional, Engelman, Daniel, additional, Essop, Mohammed R., additional, Finucane, Kirsten, additional, Gentles, Tom, additional, Guilherme, Luiza, additional, Jack, Susan J., additional, Kado, Joseph, additional, Karthikeyan, Ganesan, additional, Kim, Jerome H., additional, Kumar, A. Sampath, additional, Kumar, Raman Krishna, additional, Lang, Chim C., additional, Lennon, Diana, additional, Mirabel, Mariana, additional, Mocumbi, Ana, additional, Horton, Ari, additional, Mordi, Ify R., additional, Mwangi, Jeremiah, additional, Nascimento, Bruno, additional, Ntsekhe, Mpiko, additional, Okello, Emmy, additional, Osowicki, Joshua, additional, Parks, Tom, additional, Price, Susanna, additional, Ralph, Anna P., additional, Remenyi, Bo, additional, Sable, Craig, additional, Sadiq, Masood, additional, Senguttuvan, Nagendra Boopathy, additional, Sliwa, Karen, additional, Soma-Pillay, Priya, additional, Steer, Andrew C., additional, Vekemans, Johan, additional, Watkins, David, additional, Webb, Rachel, additional, Wilson, Nigel, additional, Wyber, Rosemary, additional, and Zühlke, Liesl, additional

Published
2021
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16. FIGO consensus guidelines on placenta accreta spectrum disorders: Conservative management†,‡

Author

Sentilhes, Loïc, Kayem, Gilles, Chandraharan, Edwin, Palacios‐Jaraquemada, José, Jauniaux, Eric, Duncombe, Greg, Klaritsch, Philipp, Chantraine, Frédéric, Kingdom, John, Grønbeck, Lene, Rull, Kristiina, Nigatu, Balkachew, Tikkanen, Minna, Sentilhes, Loïc, Asatiani, Tengiz, Leung, Wing‐Cheong, AIhaidari, Taghreed, Brennan, Donal, Kondoh, Eiji, Yang, Jeong‐In, Seoud, Muhieddine, Jegasothy, Ravindran, Espino y Sosa, Salvador, Jacod, Benoit, D’Antonio, Francesco, Shah, Nusrat, Bomba‐Opon, Dorota, Ayres‐de‐Campos, Diogo, Jeremic, Katarina, Kok, Tan Lay, Soma‐Pillay, Priya, Tul Mandić, Nataša, Lindqvist, Pelle, Arnadottir, Thora Berglind, Hoesli, Irene, Jaisamrarn, Unnop, Al Mulla, Amal, Robson, Stephen, and Cortez, Rafael

Published
2018
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17. FIGO consensus guidelines on placenta accreta spectrum disorders: Introduction†,‡

Author

Jauniaux, Eric, Ayres‐de‐Campos, Diogo, Duncombe, Greg, Klaritsch, Philipp, Chantraine, Frédéric, Kingdom, John, Grønbeck, Lene, Rull, Kristiina, Nigatu, Balkachew, Tikkanen, Minna, Sentilhes, Loïc, Asatiani, Tengiz, Leung, Wing‐Cheong, AIhaidari, Taghreed, Brennan, Donal, Kondoh, Eiji, Yang, Jeong‐In, Seoud, Muhieddine, Jegasothy, Ravindran, Espino y Sosa, Salvador, Jacod, Benoit, D’Antonio, Francesco, Shah, Nusrat, Bomba‐Opon, Dorota, Ayres‐de‐Campos, Diogo, Jeremic, Katarina, Kok, Tan Lay, Soma‐Pillay, Priya, Tul Mandić, Nataša, Lindqvist, Pelle, Arnadottir, Thora Berglind, Hoesli, Irene, Jaisamrarn, Unnop, Al Mulla, Amal, Robson, Stephen, and Cortez, Rafael

Published
2018
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18. FIGO consensus guidelines on placenta accreta spectrum disorders: Epidemiology†,‡

Author

Jauniaux, Eric, Chantraine, Frederic, Silver, Robert M., Langhoff‐Roos, Jens, Duncombe, Greg, Klaritsch, Philipp, Chantraine, Frédéric, Kingdom, John, Grønbeck, Lene, Rull, Kristiina, Nigatu, Balkachew, Tikkanen, Minna, Sentilhes, Loïc, Asatiani, Tengiz, Leung, Wing‐Cheong, AIhaidari, Taghreed, Brennan, Donal, Kondoh, Eiji, Yang, Jeong‐In, Seoud, Muhieddine, Jegasothy, Ravindran, Espino y Sosa, Salvador, Jacod, Benoit, D’Antonio, Francesco, Shah, Nusrat, Bomba‐Opon, Dorota, Ayres‐de‐Campos, Diogo, Jeremic, Katarina, Kok, Tan Lay, Soma‐Pillay, Priya, Tul Mandić, Nataša, Lindqvist, Pelle, Arnadottir, Thora Berglind, Hoesli, Irene, Jaisamrarn, Unnop, Al Mulla, Amal, Robson, Stephen, and Cortez, Rafael

Published
2018
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19. FIGO consensus guidelines on placenta accreta spectrum disorders: Nonconservative surgical management†,‡

Author

Allen, Lisa, Jauniaux, Eric, Hobson, Sebastian, Papillon‐Smith, Jessica, Belfort, Michael A., Duncombe, Greg, Klaritsch, Philipp, Chantraine, Frédéric, Kingdom, John, Grønbeck, Lene, Rull, Kristiina, Nigatu, Balkachew, Tikkanen, Minna, Sentilhes, Loïc, Asatiani, Tengiz, Leung, Wing‐Cheong, AIhaidari, Taghreed, Brennan, Donal, Kondoh, Eiji, Yang, Jeong‐In, Seoud, Muhieddine, Jegasothy, Ravindran, Espino y Sosa, Salvador, Jacod, Benoit, D’Antonio, Francesco, Shah, Nusrat, Bomba‐Opon, Dorota, Ayres‐de‐Campos, Diogo, Jeremic, Katarina, Kok, Tan Lay, Soma‐Pillay, Priya, Tul Mandić, Nataša, Lindqvist, Pelle, Arnadottir, Thora Berglind, Hoesli, Irene, Jaisamrarn, Unnop, Al Mulla, Amal, Robson, Stephen, and Cortez, Rafael

Published
2018
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20. FIGO consensus guidelines on placenta accreta spectrum disorders: Prenatal diagnosis and screening†,‡

Author

Jauniaux, Eric, Bhide, Amar, Kennedy, Anne, Woodward, Paula, Hubinont, Corrine, Collins, Sally, Duncombe, Greg, Klaritsch, Philipp, Chantraine, Frédéric, Kingdom, John, Grønbeck, Lene, Rull, Kristiina, Nigatu, Balkachew, Tikkanen, Minna, Sentilhes, Loïc, Asatiani, Tengiz, Leung, Wing‐Cheong, AIhaidari, Taghreed, Brennan, Donal, Kondoh, Eiji, Yang, Jeong‐In, Seoud, Muhieddine, Jegasothy, Ravindran, Espino y Sosa, Salvador, Jacod, Benoit, D’Antonio, Francesco, Shah, Nusrat, Bomba‐Opon, Dorota, Ayres‐de‐Campos, Diogo, Jeremic, Katarina, Kok, Tan Lay, Soma‐Pillay, Priya, Tul Mandić, Nataša, Lindqvist, Pelle, Arnadottir, Thora Berglind, Hoesli, Irene, Jaisamrarn, Unnop, Al Mulla, Amal, Robson, Stephen, and Cortez, Rafael

Published
2018
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22. Interventions for the prevention of spontaneous preterm birth: a scoping review of systematic reviews

Author

Campbell, Fiona, primary, Salam, Shumona, additional, Sutton, Anthea, additional, Jayasooriya, Shamanthi Maya, additional, Mitchell, Caroline, additional, Amabebe, Emmanuel, additional, Balen, Julie, additional, Gillespie, Bronwen M, additional, Parris, Kerry, additional, Soma-Pillay, Priya, additional, Chauke, Lawrence, additional, Narice, Brenda, additional, and Anumba, Dilichukwu O, additional

Published
2022
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24. Additional file 1 of International virtual confidential reviews of infection-related maternal deaths and near-miss in 11 low- and middle-income countries – case report series and suggested actions

Author

Okafor, Obiageli, Roos, Nathalie, Abdosh, Abdulfetah Abdulkadir, Adesina, Olubukola, Alaoui, Zaynab, Romero, William Arriaga, Assarag, Bouchra, Aworinde, Olufemi, de Bernis, Luc, Castro, Rigoberto, Chrifi, Hassan, Day, Louise Tina, Demissew, Rahel, Aceituno, María Guadalupe Flores, Gadama, Luis, Gashawbeza, Biruck, Keke, Sourou Goufodji, Govule, Philip, Gwako, George, Jayaratne, Kapila, Komboigo, Evelyne Béwendin, Lara, Bredy, Madziyire, Mugove Gerald, Mathai, Matthews, Moulki, Rachid, Moutaouadia, Iatimad, Munjanja, Stephen, Fletes, Carlos Alberto Ochoa, Ortiz, Edgar Ivan, Ouedraogo, Henri Gautier, Qureshi, Zahida, Recidoro, Zenaida Dy, Senanayake, Hemantha, Soma-Pillay, Priya, Tin, Khaing Nwe, Sedami, Pascal, Worku, Dawit, and Bonet, Mercedes

Abstract

Additional file 1. Supplementary appendix to “International virtual confidential reviews of infection-related maternal deaths and near-miss in 11 low- and middle-income countries – Case report series and suggested actions. Study forms used for data collection and during the external review meetings. Results of a baseline assessment of maternal death review (MDR) committees and practices in participating GLOSS facilities. Additional information on the causes of deaths and distribution of modifiable factors described in this study.

Published
2022
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25. Geographic variation in management of patients with placenta accreta spectrum: An international survey of experts (GPASS)

Author

Brown, Alec D., primary, Hart, Jessica M., additional, Modest, Anna M., additional, Hess, Philip E., additional, Abbas, Ahmed M., additional, Nieto‐Calvache, Albaro J., additional, Bhide, Amarnath, additional, Lim, Boon, additional, Dunjin, Chen, additional, Palacios‐Jaraquemada, José, additional, Sentilhes, Loïc, additional, Soma‐Pillay, Priya, additional, Aryananda, Rozi A., additional, Hantoushzadeh, Sedigheh, additional, Wang, Shan, additional, Shamshirsaz, Alireza A., additional, and Shainker, Scott A., additional

Published
2021
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26. “Suction Tube Uterine Tamponade” for treatment of refractory postpartum hemorrhage: Internal feasibility and acceptability pilot of a randomized clinical trial

Author

Cebekhulu, Sylvia N., primary, Abdul, Hazmath, additional, Batting, Joanne, additional, Chauke, Lawrence, additional, Dlakavu, Fuziwe, additional, Fawcus, Sue, additional, Govender, Logie, additional, Majeke, Busiwe, additional, Mbongozi, Xolani, additional, Singata‐Madliki, Mandisa, additional, Middleton, Katrin, additional, Mlandu, Philiswa, additional, Naidoo, Poovangela, additional, Ndaba, Sanele, additional, Soma‐Pillay, Priya, additional, Spence, Trevi, additional, Ntambua, Symphorien C., additional, and Hofmeyr, Justus, additional

Published
2021
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28. Maternal characteristics and pregnancy outcomes of hospitalized pregnant women with SARS‐CoV‐2 infection in South Africa: An International Network of Obstetric Survey Systems‐based cohort study

Author

Budhram, Samantha, primary, Vannevel, Valerie, additional, Botha, Tanita, additional, Chauke, Lawrence, additional, Bhoora, Shastra, additional, Balie, Gaynor M., additional, Odell, Natalie, additional, Lombaard, Hennie, additional, Wise, Amy, additional, Georgiou, Chrysanthi, additional, Ngxola, Nondumiso, additional, Wynne, Emma, additional, Mbewu, Unati, additional, Mabenge, Mfundo, additional, Phinzi, Sibusiso, additional, Gubu‐Ntaba, Nontsikelelo, additional, Goldman, Gareth, additional, Tunkyi, Kay, additional, Prithipal, Sudhir, additional, Naidoo, Keshree, additional, Venkatachalam, Santhi, additional, Moodley, Terence, additional, Mould, Sean, additional, Hlabisa, Mzuvele, additional, Govender, Logie, additional, Maistry, Charlene, additional, Habineza, John P., additional, Israel, Priya, additional, Foolchand, Serantha, additional, Tsibiyane, Nomandla V., additional, Panday, Mala, additional, Soma‐Pillay, Priya, additional, Adam, Sumaiya, additional, Molokoane, Felicia, additional, Mojela, Matthew S., additional, Rensburg, Elizabeth J., additional, Mashamba, Tshililo, additional, Matjila, Mushi, additional, Fawcus, Sue, additional, Osman, Ayesha, additional, Venter, Mareli, additional, Petro, Gregory, additional, Fakier, Ahminah, additional, Langenegger, Eduard, additional, Cluver, Catherine A., additional, Bekker, Adrie, additional, Waard, Liesl, additional, Stewart, Chantal, additional, Ngene, Nnabuike C., additional, Lunda, Ongombe, additional, N.Cebekhulu, Sylvia, additional, Moodley, Siva, additional, Koranteng‐Peprah, Mama‐Asu, additional, Ati, Emmanuel M. C., additional, Maswime, Salome, additional, and Yates, Laura M., additional

Published
2021
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31. Agency under constraint: Adolescent accounts of pregnancy and motherhood in informal settlements in South Africa.

Author

Gillespie, Bronwen, Allen, Haddijatou, Pritchard, Matthew, Soma-Pillay, Priya, Balen, Julie, and Anumba, Dilly

Subjects
MOTHERHOOD & psychology, HEALTH services accessibility, SOCIAL support, TEENAGE mothers, QUALITATIVE research, TEENAGE pregnancy, PSYCHOSOCIAL factors, RESEARCH funding, POVERTY, PSYCHOLOGICAL adaptation, HEALTH self-care, UNPLANNED pregnancy, SEXUAL health, ADOLESCENCE
Abstract

Progress in adolescent sexual and reproductive health (SRH) remains unequal: adolescent pregnancies are more likely to occur in marginalised communities, or in very poor households. This study aimed to comprehend from adolescents' own perspectives, the circumstances of falling pregnant and coping with motherhood in informal settlements in South Africa, to better understand the SRH challenges adolescents in these settings may face. A qualitative study was carried out over a two-month period in 2019 to analyse the perceptions held by adolescents in informal settlements served by four community-level clinics in the adjacent township. We found that adolescents face overlapping barriers in seeking to avoid unintended pregnancy in informal settlements. Once they become mothers, their trajectory is limited by the resources and support available from their own parents, particularly their mothers, and to a lesser extent, their partners. We draw on the concept of agency to examine their accounts and to highlight the importance of addressing broader contextual constraints. [ABSTRACT FROM AUTHOR]

Published
2022
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32. Coronavirus and Pregnancy: The Challenges of the 21st Century: A Review.

Author

Adam, Sumaiya, Pheiffer, Carmen, Dias, Stephanie, Hlongwane, Tsakane, Vannevel, Valerie, Soma-Pillay, Priya, and Abdullah, Fareed

Subjects
COVID-19, SARS-CoV-2, VACCINE hesitancy, VACCINATION, COVID-19 pandemic, CORONAVIRUSES, PREGNANT women
Abstract

Despite many advances in medicine we are still faced with emerging pathogens. Pregnant women have been disproportionately affected by previous coronavirus outbreaks. The COVID-19 pandemic has not affected pregnant women as greatly as SARS-CoV and MERS, but has posed other challenges such as the need for quarantine and isolation, limited access to antenatal care, use of personal protective equipment (PPE), vaccine hesitancy and inequities in vaccine access and therapeutics between rich countries and the global south. This review will describe the impact of the significant coronaviruses on pregnancy, with special focus on the challenges being encountered by the SARS-CoV-2 global pandemic. [ABSTRACT FROM AUTHOR]

Published
2022
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33. "Suction Tube Uterine Tamponade" for treatment of refractory postpartum hemorrhage: Internal feasibility and acceptability pilot of a randomized clinical trial.

Author

Cebekhulu, Sylvia N., Abdul, Hazmath, Batting, Joanne, Chauke, Lawrence, Dlakavu, Fuziwe, Fawcus, Sue, Govender, Logie, Majeke, Busiwe, Mbongozi, Xolani, Singata-Madliki, Mandisa, Middleton, Katrin, Mlandu, Philiswa, Naidoo, Poovangela, Ndaba, Sanele, Soma-Pillay, Priya, Spence, Trevi, Ntambua, Symphorien C., and Hofmeyr, Justus

Published
2022
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34. Geographic variation in management of patients with placenta accreta spectrum: An international survey of experts (GPASS).

Author

Brown, Alec D., Hart, Jessica M., Modest, Anna M., Hess, Philip E., Abbas, Ahmed M., Nieto-Calvache, Albaro J., Bhide, Amarnath, Boon Lim, Chen Dunjin, Palacios-Jaraquemada, José, Sentilhes, Loïc, Soma-Pillay, Priya, Aryananda, Rozi A., Hantoushzadeh, Sedigheh, Shan Wang, Shamshirsaz, Alireza A., and Shainker, Scott A.

Published
2022
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35. Vaginal progesterone vs cervical cerclage for the prevention of preterm birth in women with a sonographic short cervix, previous preterm birth, and singleton gestation: a systematic review and indirect comparison metaanalysis

Author

Conde-Agudelo, Agustin, Romero, Roberto, Nicolaides, Kypros, Chaiworapongsa, Tinnakorn, OʼBrien, John M., Cetingoz, Elcin, da Fonseca, Eduardo, Creasy, George, Soma-Pillay, Priya, Fusey, Shalini, Cam, Cetin, Alfirevic, Zarko, and Hassan, Sonia S.

Published
2013
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36. Vaginal progesterone in women with an asymptomatic sonographic short cervix in the midtrimester decreases preterm delivery and neonatal morbidity: a systematic review and metaanalysis of individual patient data

Author

Romero, Roberto, Nicolaides, Kypros, Conde-Agudelo, Agustin, Tabor, Ann, OʼBrien, John M., Cetingoz, Elcin, Da Fonseca, Eduardo, Creasy, George W., Klein, Katharina, Rode, Line, Soma-Pillay, Priya, Fusey, Shalini, Cam, Cetin, Alfirevic, Zarko, and Hassan, Sonia S.

Published
2012
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41. FIGO classification for the clinical diagnosis of placenta accreta spectrum disorders

Author

Jauniaux, Eric, Ayres-de-Campos, Diogo, Langhoff‐Roos, Jens, Fox, Karin A., Collins, Sally, Duncombe, Greg, Klaritsch, Philipp, Chantraine, Frédéric, Kingdom, John, Grønbeck, Lene, Rull, Kristiina, Tikkanen, Minna, Sentilhes, Loïc, Asatiani, Tengiz, Leung, Wing‐Cheong, AIhaidari, Taghreed, Brennan, Donal, Seoud, Muhieddine, Hussein, Ahmed Mahmoud, Jegasothy, Ravindran, Shah, Kamal Nusrat, Bomba‐Opon, Dorota, Hubinont, Corinne, Soma‐Pillay, Priya, Mandić, Nataša Tul, Lindqvist, Pelle, Arnadottir, Berglind, Hoesli, Irene, Cortez, Rafael, and Repositório da Universidade de Lisboa

Subjects
Increta, Placenta, Accreta, Percreta, Classification
Abstract

© 2019 International Federation of Gynecology and Obstetrics, Placenta accreta spectrum is impacting maternal health outcomes globally and its prevalence is likely to increase. Maternal outcomes depend on identification of the condition before or during delivery and, in particular, on the differential diagnosis between its adherent and invasive forms. However, accurate estimation of its prevalence and outcome is currently problematic because of the varying use of clinical criteria to define it at birth and the lack of detailed pathologic examination in most series. Adherence to this new International Federation of Gynecology and Obstetrics (FIGO) classification should improve future systematic reviews and meta-analyses and provide more accurate epidemiologic data which are essential to develop new management strategies.

Published
2019

42. The importance of cardiovascular pathology contributing to maternal death: Confidential Enquiry into Maternal Deaths in South Africa, 2011–2013

Author

Soma-Pillay, Priya, Seabe, Joseph, and Sliwa, Karen

Subjects
Adult, Pediatrics, medicine.medical_specialty, Adolescent, Referral, Heart disease, Peripartum cardiomyopathy, Pregnancy Complications, Cardiovascular, peripartum cardiomyopathy, Disease, 030204 cardiovascular system & hematology, Cardiovascular System, valve disease, South Africa, 03 medical and health sciences, 0302 clinical medicine, Pregnancy, Cause of Death, Humans, Medicine, 030212 general & internal medicine, Child, Developing Countries, Cause of death, business.industry, Cardiovascular Topics, General Medicine, rheumatic heart disease, medicine.disease, Low birth weight, Maternal Mortality, valve thrombosis, Emergency medicine, Maternal Death, Female, Maternal death, cardiac disease in pregnancy, medicine.symptom, Cardiology and Cardiovascular Medicine, business, cardiomyopathy
Abstract

Summary Aims Cardiac disease is emerging as an important contributor to maternal deaths in both lower-to-middle and higher-income countries. There has been a steady increase in the overall institutional maternal mortality rate in South Africa over the last decade. The objectives of this study were to determine the cardiovascular causes and contributing factors of maternal death in South Africa, and identify avoidable factors, and thus improve the quality of care provided. Methods Data collected via the South African National Confidential Enquiry into Maternal Deaths (NCCEMD) for the period 2011–2013 for cardiovascular disease (CVD) reported as the primary pathology was analysed. Only data for maternal deaths within 42 days post-delivery were recorded, as per statutory requirement. One hundred and sixty-nine cases were reported for this period, with 118 complete hospital case files available for assessment and data analysis. Results Peripartum cardiomyopathy (PPCM) (34%) and complications of rheumatic heart disease (RHD) (25.3%) were the most important causes of maternal death. Hypertensive disorders of pregnancy, HIV disease infection and anaemia were important contributing factors identified in women who died of peripartum cardiomyopathy. Mitral stenosis was the most important contributor to death in RHD cases. Of children born alive, 71.8% were born preterm and 64.5% had low birth weight. Seventy-eight per cent of patients received antenatal care, however only 33.7% had a specialist as an antenatal care provider. Avoidable factors contributing to death included delay in patients seeking help (41.5%), lack of expertise of medical staff managing the case (29.7%), delay in referral to the appropriate level of care (26.3%), and delay in appropriate action (36.4%). Conclusion The pattern of CVD contributing to maternal death in South Africa was dominated by PPCM and complications of RHD, which could, to a large extent, have been avoided. It is likely that there were many CVD deaths that were not reported, such as late maternal mortality (up to one year postpartum). Infrastructural changes, use of appropriate referral algorithm and training of primary, secondary and tertiary staff in CVD complicating pregnancy is likely to improve the outcome. The use of simple screening equipment and point-of-care testing for early-onset heart failure should be explored via research projects.

Published
2016

43. Quality of life 1 year after a maternal near-miss event.

Author

Soma‐Pillay, Priya, Makin, Jennifer D., Pattinson, Robert C., and Soma-Pillay, Priya

Subjects
*PERINATAL death, *QUALITY of life, *PREGNANCY complications, *TERTIARY care, *MEDICAL care, *LONGITUDINAL method, *MATERNAL mortality, *SPECIALTY hospitals
Abstract

Objectives: To evaluate quality of life (QoL) parameters among women categorized with a maternal near-miss during pregnancy.Methods: The present prospective cohort study was conducted at a tertiary referral hospital in South Africa between April 1, 2013, and March 31, 2016. Patients who experienced maternal near-miss events were included and patients with uncomplicated low-risk pregnancies were enrolled as a control group. Various parameters were assessed using a WHO QoL questionnaire.Results: The maternal near-miss and uncomplicated low-risk pregnancy (control) groups comprised 95 and 51 women. The maternal near-miss group scored lower than the control group in all four domains of the questionnaire (P<0.001). Overall, 42 (82%) women in the control group and 41 (43%) women in the maternal near-miss group desired future fertility (P<0.001). Women in the maternal near-miss group who had experienced perinatal loss scored lower in the physical health and well-being (P=0.009), psychological health and well-being (P=0.007), and environment (P=0.031) domains compared with women in the maternal near-miss group who experienced a live delivery. Nonetheless, QoL scores among women in the maternal near-miss group who had experienced perinatal loss remained lower than those reported by women in the control group (P<0.001).Conclusion: A maternal near-miss event during pregnancy was associated with reduced QoL, especially among women who had experienced perinatal loss. [ABSTRACT FROM AUTHOR]

Published
2018
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45. VAGINAL PROGESTERONE VERSUS CERVICAL CERCLAGE FOR THE PREVENTION OF PRETERM BIRTH IN WOMEN WITH A SONOGRAPHIC SHORT CERVIX, SINGLETON GESTATION, AND PREVIOUS PRETERM BIRTH: A SYSTEMATIC REVIEW AND INDIRECT COMPARISON META-ANALYSIS

Author

CONDE-AGUDELO, Agustin, ROMERO, Roberto, NICOLAIDES, Kypros, CHAIWORAPONGSA, Tinnakorn, O'BRIEN, John M., CETINGOZ, Elcin, DA FONSECA, Eduardo, CREASY, George, SOMA-PILLAY, Priya, FUSEY, Shalini, CAM, Cetin, ALFIREVIC, Zarko, and HASSAN, Sonia S.

Subjects
Administration, Intravaginal, Pregnancy, Humans, Premature Birth, Female, Cervix Uteri, Progestins, Article, Progesterone, Cerclage, Cervical, Ultrasonography
Abstract

No randomized controlled trial has compared vaginal progesterone and cervical cerclage directly for the prevention of preterm birth in women with a sonographic short cervix in the mid trimester, singleton gestation, and previous spontaneous preterm birth. We performed an indirect comparison of vaginal progesterone vs cerclage using placebo/no cerclage as the common comparator.Adjusted indirect metaanalysis of randomized controlled trials.Four studies that evaluated vaginal progesterone vs placebo (158 patients) and 5 studies that evaluated cerclage vs no cerclage (504 patients) were included. Both interventions were associated with a statistically significant reduction in the risk of preterm birth at32 weeks of gestation and composite perinatal morbidity and mortality compared with placebo/no cerclage. Adjusted indirect metaanalyses did not show statistically significant differences between vaginal progesterone and cerclage in the reduction of preterm birth or adverse perinatal outcomes.Based on state-of-the-art methods for indirect comparisons, either vaginal progesterone or cerclage are equally efficacious in the prevention of preterm birth in women with a sonographic short cervix in the mid trimester, singleton gestation, and previous preterm birth. Selection of the optimal treatment needs to consider adverse events, cost and patient/clinician preferences.

Published
2012

50. List of Contributors

Author

Arulkumaran KB, Sir Sabaratnam, Addei, Anthony, Allen, Victoria M., Baskett, Thomas F., Barrett, Jon F.R., Bergholt, T., Brennan, D.J., Brophy, D.P., Calder, Andrew A., Cameron, Alan, Chandraharan, E., Crofts, Joanna F., Cunningham, Simon, Draycott, Timothy J., Farine, Dan, Greene, Richard A., Hayes, Niamh E., Hedditch, A., Higgins, Shane P., Hinshaw, Kim, Hotton, E.J., Impey, L., Johnston, Tracey A., Ledingham, Marie Anne, Colgáin, Siaghal Mac, Maxwell, Cynthia, Norman, Jane E., Nugent, Fiona, O’Brien, Stephen, Olah, Karl S.J., Palacios Jaraquemada, J.M., Paterson-Brown, S., Pattinson, Robert C., Pilarski, Nicole, Renwick, S., Richardson, Heather, Robson, Michael S., Shinar, Shiri, Siassakos, Dimitrios, Soma-Pillay, Priya, Cert (Maternal and Fetal Medicine), Sultan, Abdul H., Thakar, Ranee, Thomson, Andrew J., Turner, Michael J., Tuffnell, Derek J., Ugwumadu, A., van den Akker, Thomas, Walsh, Jennifer M., and Weeks, Andrew D.

Published
2020
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