1. The extended transmission of cold atmospheric plasma-induced anticancer effects between cells.
- Author
-
Zhang, Jishen, Wu, Tong, Jing, Xixi, Xu, Shengduo, Wang, Zifeng, Lin, Jiao, Guo, Li, Liu, Dingxin, Zhang, Hao, Xu, Yujing, Wang, Xiaohua, and Rong, Mingzhe
- Subjects
- *
COLD atmospheric plasmas , *ANTINEOPLASTIC agents , *REACTIVE oxygen species , *CANCER cells , *PHYSIOLOGICAL effects of cold temperatures - Abstract
The application of cold atmospheric plasma (CAP) in cancer therapy has recently received extensive attention. However, researchers have mainly studied the effects of CAP on plasma-irradiated cancer cells and have not determined whether CAP affects surrounding or distant non-irradiated cancer cells. Here, the viability and intracellular reactive oxygen species levels of plasma-irradiated and non-irradiated cancer cells were monitored in vitro. Our results showed that CAP may induce plasma-irradiated cancer cells (A549 cells, A375 cells, J82 cells and HT29 cells) to secrete soluble factors into the cell culture medium, which can transmit plasma-induced anticancer effects from plasma-irradiated cancer cells to non-irradiated cancer cells. Our research confirmed that plasma-induced anticancer effects can be transmitted between cancer cells. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF