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The rarity of Huntington's disease (HD) parturients implies that anesthesiologists have little exposure to the management of these patients. We explore techniques for the management of a 21-year-old parturient with symptomatic HD who underwent successful neuraxial anesthesia for labor and subsequent cesarean delivery. We provide guidance on perioperative medications for comorbidities associated with HD. Dexmedetomidine, which we administered neuraxially, appears to have significant potential for the perioperative diminution of choreiform movements. Current anesthetic management of HD cannot be informed by traditional research methodology and therefore much information must be gleaned from the limited available case reports., Competing Interests: The authors declare no conflicts of interest., (Copyright © 2025 International Anesthesia Research Society.)

Recent advancements in therapeutics and risk reduction in the management of cystic fibrosis have increased the life expectancy of cystic fibrosis patients to the fifth decade of life. As the life expectancy of cystic fibrosis patients has increased, more cystic fibrosis patients have opted to pursue pregnancy. Normal pregnancy is accompanied by physiological changes that affect anesthetic management. These normal physiological changes, combined with the pathological manifestations of cystic fibrosis, create a unique set of anesthetic challenges. Here, we report on the management and clinical course of a 37-year-old parturient with cystic fibrosis, focusing on the anesthetic approach., Competing Interests: The authors declare no conflicts of interest., (Copyright © 2025 Richard Pham et al. Case Reports in Anesthesiology published by John Wiley & Sons Ltd.)

Post-dural puncture headache (PDPH) is a debilitating complication of neuraxial anesthesia, particularly prevalent in obstetric patients, usually characterized by a postural headache. PDPH is hypothesized to result from cerebrospinal fluid leakage through a dural puncture, triggering symptoms like neck stiffness and subjective hearing changes. While conservative measures are common for treatment, more refractory cases may require invasive interventions such as an epidural blood patch (EBP). Recent studies have shown promise in using nebulized dexmedetomidine (nDEX) for PDPH, offering a non-invasive alternative to EBP. Two case presentations illustrate the efficacy of nDEX in resolving PDPH symptoms rapidly and completely. These cases underscore the need for exploring novel therapeutic options, especially in obstetric patients where safe and prompt relief is essential for maternal and newborn well-being. While the EBP remains the gold standard, its limitations of accessibility and invasiveness highlight the significance of investigating alternatives like nDEX., Competing Interests: Declarations. Ethics approval and consent to participate: Consent was granted by the patients to write the case report. Ethics approval not applicable. Consent for publication: Informed written consent was granted by the patients to write the case report along with the publishing of the clinical details. Competing interests: The authors declare no competing interests. Author contributions: All of the authors (JT, LS, CM, PC, AS) made substantial contributions to the conception and design, or acquisition of data, or analysis and interpretation of data; they have been involved in drafting the manuscript or revising it critically for important intellectual content; have given final approval of the version to be published., (© 2025. The Author(s).)

The perioperative surgical home (PSH) is a care delivery model designed to improve the perioperative and long-term outcomes of patients undergoing surgery by promoting holistic care and seamless cooperation between different services and subspecialties. An aging population and increased surgical complexity have led to renewed interest in PSH models. An 86-year-old female with diabetes and critical limb ischemia presented with sepsis due to right calcaneal gangrene. A structured, comprehensive evaluation by the inpatient PSH service identified perioperative concerns including malnutrition and elevated cardiac risk and led to the discovery of an airway-compromising mass. A coordinated care plan, devised by the PSH team resulted in a joint operation by otolaryngology and orthopedic surgery departments, thus avoiding what would have been an otherwise unexpected difficult airway, and likely complications. Our case highlights the explicit and implicit benefits of interdisciplinary care coordinated by an inpatient PSH service, which includes risk stratification, comprehensive evaluation, and prevention of complications., Competing Interests: Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Lee et al.)

Pubic symphysis diastasis (PSD) is the widening of the pubic symphysis which can occur during the peripartum period. PSD commonly presents as pelvic pain with associated neuropathies rarely reported. In this report we describe the unique presentation of PSD with associated motor and sensory deficits in a 19-year-old postpartum patient. Two days following vaginal delivery, the patient complained of diffuse body pain, generalized weakness, and lower extremity paresthesia without any other neurological deficits. PSD was diagnosed by radiograph of the pelvis and her symptoms swiftly improved following conservative management of the diastasis. Further, we discuss the potential etiology of this patient's presentation as well as differential diagnosis with similar presentations., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Soloniuk et al.)