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146 results on '"Solis, Patricia"'

1. Blood levels of cytokines highlight the role of inflammation in Alzheimer's disease

Author

Campanelli, Lorenzo, Galeano, Pablo, Prestia, Federico A., Cuesta, Carolina, Dalmasso, Maria C., Flores-López, María, Gona, Cristian, Irureta, Nicolás, Kairiyama, Claudia, Lisso, Julieta, López-Gambero, Antonio Jesús, Mintz, Ines, Medel, Nancy, Campuzano, Karen S., Muchnik, Carolina, Novack, Gisela V., Olivar, Natividad, Quiroga, Ivana, Requena-Ocaña, Nerea, Reyes-Bueno, Jose Antonio, Serrano-Castro, Pedro, Sevillano, Zulma, Solis, Patricia, Suárez, Juan, Villella, Ivana, Wukitsevits, Nancy, Castaño, Eduardo M., Taragano, Fernando, Kochen, Silvia, Politis, Daniel G., Brusco, Luis I., Rodríguez de Fonseca, Fernando, and Morelli, Laura

Published
2025
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2. Reflecting on the YouthMappers Movement

Author

Anderson, Jennings, Blevins, Chad, Cowan, Nuala, Carney-Nedelman, Dara, Clark, Courtney, Crino, Michael, Engstrom, Ryan, Hinton, Richard, Mann, Michael, McCusker, Brent, Nealon, Rory, Solís, Patricia, Zeballos, Marcela, Solís, Patricia, editor, and Zeballos, Marcela, editor

Published
2023
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5. Introduction

Author

Solís, Patricia, Zeballos, Marcela, Solís, Patricia, editor, and Zeballos, Marcela, editor

Published
2023
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7. Dementia in Latin America: Paving the way toward a regional action plan.

Author

Parra, Mario Alfredo, Baez, Sandra, Sedeño, Lucas, Gonzalez Campo, Cecilia, Santamaría-García, Hernando, Aprahamian, Ivan, Bertolucci, Paulo Hf, Bustin, Julian, Camargos Bicalho, Maria Aparecida, Cano-Gutierrez, Carlos, Caramelli, Paulo, Chaves, Marcia LF, Cogram, Patricia, Beber, Bárbara Costa, Court, Felipe A, de Souza, Leonardo Cruz, Custodio, Nilton, Damian, Andres, de la Cruz, Myriam, Diehl Rodriguez, Roberta, Brucki, Sonia Maria Dozzi, Fajersztajn, Lais, Farías, Gonzalo A, De Felice, Fernanda G, Ferrari, Raffaele, de Oliveira, Fabricio Ferreira, Ferreira, Sergio T, Ferretti, Ceres, Figueredo Balthazar, Marcio Luiz, Ferreira Frota, Norberto Anizio, Fuentes, Patricio, García, Adolfo M, Garcia, Patricia J, de Gobbi Porto, Fábio Henrique, Duque Peñailillo, Lissette, Engler, Henry Willy, Maier, Irene, Mata, Ignacio F, Gonzalez-Billault, Christian, Lopez, Oscar L, Morelli, Laura, Nitrini, Ricardo, Quiroz, Yakeel T, Guerrero Barragan, Alejandra, Huepe, David, Pio, Fabricio Joao, Suemoto, Claudia Kimie, Kochhann, Renata, Kochen, Silvia, Kumfor, Fiona, Lanata, Serggio, Miller, Bruce, Mansur, Leticia Lessa, Hosogi, Mirna Lie, Lillo, Patricia, Llibre Guerra, Jorge, Lira, David, Lopera, Francisco, Comas, Adelina, Avila-Funes, José Alberto, Sosa, Ana Luisa, Ramos, Claudia, Resende, Elisa de Paula França, Snyder, Heather M, Tarnanas, Ioannis, Yokoyama, Jenifer, Llibre, Juan, Cardona, Juan Felipe, Possin, Kate, Kosik, Kenneth S, Montesinos, Rosa, Moguilner, Sebastian, Solis, Patricia Cristina Lourdes, Ferretti-Rebustini, Renata Eloah de Lucena, Ramirez, Jeronimo Martin, Matallana, Diana, Mbakile-Mahlanza, Lingani, Marques Ton, Alyne Mendonça, Tavares, Ronnielly Melo, Miotto, Eliane C, Muniz-Terrera, Graciela, Muñoz-Nevárez, Luis Arnoldo, Orozco, David, Okada de Oliveira, Maira, Piguet, Olivier, Pintado Caipa, Maritza, Piña Escudero, Stefanie Danielle, Schilling, Lucas Porcello, Rodrigues Palmeira, André Luiz, Yassuda, Mônica Sanches, Santacruz-Escudero, Jose Manuel, Serafim, Rodrigo Bernardo, Smid, Jerusa, Slachevsky, Andrea, Serrano, Cecilia, Soto-Añari, Marcio, Takada, Leonel Tadao, Grinberg, Lea Tenenholz, Teixeira, Antonio Lucio, and Barbosa, Maira Tonidandel

Subjects
Latin America, biomarkers, clinical trials, dementia, epidemiology, evidence-based recommendations, genetics, knowledge to action framework, networking and translational research, nonpharmacological interventions, Dementia, Clinical Research, Brain Disorders, Aging, Acquired Cognitive Impairment, Prevention, Neurological, Clinical Sciences, Neurosciences, Geriatrics
Abstract

Across Latin American and Caribbean countries (LACs), the fight against dementia faces pressing challenges, such as heterogeneity, diversity, political instability, and socioeconomic disparities. These can be addressed more effectively in a collaborative setting that fosters open exchange of knowledge. In this work, the Latin American and Caribbean Consortium on Dementia (LAC-CD) proposes an agenda for integration to deliver a Knowledge to Action Framework (KtAF). First, we summarize evidence-based strategies (epidemiology, genetics, biomarkers, clinical trials, nonpharmacological interventions, networking, and translational research) and align them to current global strategies to translate regional knowledge into transformative actions. Then we characterize key sources of complexity (genetic isolates, admixture in populations, environmental factors, and barriers to effective interventions), map them to the above challenges, and provide the basic mosaics of knowledge toward a KtAF. Finally, we describe strategies supporting the knowledge creation stage that underpins the translational impact of KtAF.

Published
2021

17. Segment Anything Model Can Not Segment Anything: Assessing AI Foundation Model's Generalizability in Permafrost Mapping

Author

Li, Wenwen, Hsu, Chia-Yu, Wang, Sizhe, Yang, Yezhou, Lee, Hyunho, Liljedahl, Anna, Witharana, Chandi, Yang, Yili, Rogers, Brendan M., Arundel, Samantha T., Jones, Matthew B., McHenry, Kenton, Solis, Patricia, Li, Wenwen, Hsu, Chia-Yu, Wang, Sizhe, Yang, Yezhou, Lee, Hyunho, Liljedahl, Anna, Witharana, Chandi, Yang, Yili, Rogers, Brendan M., Arundel, Samantha T., Jones, Matthew B., McHenry, Kenton, and Solis, Patricia

Abstract

This paper assesses trending AI foundation models, especially emerging computer vision foundation models and their performance in natural landscape feature segmentation. While the term foundation model has quickly garnered interest from the geospatial domain, its definition remains vague. Hence, this paper will first introduce AI foundation models and their defining characteristics. Built upon the tremendous success achieved by Large Language Models (LLMs) as the foundation models for language tasks, this paper discusses the challenges of building foundation models for geospatial artificial intelligence (GeoAI) vision tasks. To evaluate the performance of large AI vision models, especially Meta's Segment Anything Model (SAM), we implemented different instance segmentation pipelines that minimize the changes to SAM to leverage its power as a foundation model. A series of prompt strategies was developed to test SAM's performance regarding its theoretical upper bound of predictive accuracy, zero-shot performance, and domain adaptability through fine-tuning. The analysis used two permafrost feature datasets, ice-wedge polygons and retrogressive thaw slumps because (1) these landform features are more challenging to segment than manmade features due to their complicated formation mechanisms, diverse forms, and vague boundaries; (2) their presence and changes are important indicators for Arctic warming and climate change. The results show that although promising, SAM still has room for improvement to support AI-augmented terrain mapping. The spatial and domain generalizability of this finding is further validated using a more general dataset EuroCrop for agricultural field mapping. Finally, we discuss future research directions that strengthen SAM's applicability in challenging geospatial domains.

Published
2024

20. First genome‐wide association study on Alzheimer’s disease in the Argentinian and the Chilean populations

Author

Dalmasso, Maria Carolina, primary, de Rojas, Itziar, additional, Olivar, Natividad, additional, Muchnik, Carolina, additional, Angel, Bárbara, additional, Gogler, Sergio, additional, Sanchez‐Avalos, Mariana S, additional, Chacon, Maria Victoria, additional, Aránguiz, Rafael, additional, Orellana, Paulina, additional, Cuesta, Carolina, additional, Galeano, Pablo, additional, Campanelli, Lorenzo, additional, Novack, Gisella V, additional, Medel, Nancy, additional, Lisso, Julieta, additional, Sevillano, Zulma, additional, Irureta, Nicolas, additional, Castaño, Eduardo M, additional, Montrreal, Laura, additional, Heilmann‐Heimbach, Stefanie, additional, Mintz, Ines, additional, Villella, Ivana, additional, Lambert, Jean‐Charles, additional, Solis, Patricia, additional, Politis, Daniel, additional, Mangone, Carlos A, additional, Gonzalez‐Billault, Christian, additional, Boada, Mercè, additional, Tárraga, Lluís, additional, Slachevsky, Andrea, additional, Albala, Cecilia, additional, Fuentes, Patricio, additional, Kochen, Silvia, additional, Brusco, Luis Ignacio, additional, Ruiz, Agustin, additional, Morelli, Laura, additional, and Ramirez, Alfredo, additional

Published
2023
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21. The first genome‐wide association study in the Argentinian and Chilean populations identifies shared genetics with Europeans in Alzheimer's disease

Author

Dalmasso, Maria Carolina, primary, de Rojas, Itziar, additional, Olivar, Natividad, additional, Muchnik, Carolina, additional, Angel, Bárbara, additional, Gloger, Sergio, additional, Sanchez Abalos, Mariana Soledad, additional, Chacón, María Victoria, additional, Aránguiz, Rafael, additional, Orellana, Paulina, additional, Cuesta, Carolina, additional, Galeano, Pablo, additional, Campanelli, Lorenzo, additional, Novack, Gisela Vanina, additional, Martinez, Luis Eduardo, additional, Medel, Nancy, additional, Lisso, Julieta, additional, Sevillano, Zulma, additional, Irureta, Nicolás, additional, Castaño, Eduardo Miguel, additional, Montrreal, Laura, additional, Thoenes, Michaela, additional, Hanses, Claudia, additional, Heilmann‐Heimbach, Stefanie, additional, Kairiyama, Claudia, additional, Mintz, Inés, additional, Villella, Ivana, additional, Rueda, Fabiana, additional, Romero, Amanda, additional, Wukitsevits, Nancy, additional, Quiroga, Ivana, additional, Gona, Cristian, additional, Lambert, Jean‐Charles, additional, Solis, Patricia, additional, Politis, Daniel Gustavo, additional, Mangone, Carlos Alberto, additional, Gonzalez‐Billault, Christian, additional, Boada, Mercè, additional, Tàrraga, Lluís, additional, Slachevsky, Andrea, additional, Albala, Cecilia, additional, Fuentes, Patricio, additional, Kochen, Silvia, additional, Brusco, Luis Ignacio, additional, Ruiz, Agustín, additional, Morelli, Laura, additional, and Ramírez, Alfredo, additional

Published
2023
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22. Transferability of a European-derived Alzheimer’s Disease Genetic Risk Score across Multi-Ancestry Populations

Author

Nicolas, Aude, primary, Grenier-Boley, Benjamin, additional, Sherva, Richard, additional, Kim, Yoontae, additional, Kikuchi, Masataka, additional, de Rojas, Itziar, additional, Dalmasso, Carolina, additional, Zhou, Xiaopu, additional, Guen, Yann Le, additional, Arboleda-Bustos, Carlos E, additional, Camargos Bicalho, Maria Aparecida, additional, Guerchet, Maëlenn, additional, van der Lee, Sven, additional, Goss, Monica, additional, Castillo, Atahualpa, additional, Bellenguez, Céline, additional, Küçükali, Fahri, additional, Satizabal Barrera, Claudia, additional, Fongang, Bernard, additional, yang, Qiong, additional, Peters, Oliver, additional, Schneider, Anja, additional, Dichgans, Martin, additional, Rujescu, Dan, additional, Scherbaum, Norbert, additional, Deckert, Jürgen, additional, Riedel-Heller, Steffi, additional, Hausner, Lucrezia, additional, Molina Porcel, Laura, additional, Düzel, Emrah, additional, Grimmer, Timo, additional, Wiltfang, Jens, additional, Heilmann-Heimbach, Stefanie, additional, Moebus, Susanne, additional, Tegos, Thomas, additional, Scarmeas, Nikolaos, additional, Dols-Icardo, Oriol, additional, Moreno, Fermin, additional, Pérez-Tur, Jordi, additional, Bullido, María J., additional, Pastor, Pau, additional, Sánchez-Valle, Raquel, additional, Álvarez, Victoria, additional, Cao, Han, additional, Ip, Nancy Y., additional, Fu, Amy K. Y., additional, Ip, Fanny C. F., additional, Olivar, Natividad, additional, Muchnik, Carolina, additional, Cuesta, Carolina, additional, Campanelli, Lorenzo, additional, Solis, Patricia, additional, Politis, Daniel Gustavo, additional, Kochen, Silvia, additional, Brusco, Luis Ignacio, additional, Boada, Mercè, additional, García-González, Pablo, additional, Puerta, Raquel, additional, Mir, Pablo, additional, Real, Luis M, additional, Piñol-Ripoll, Gerard, additional, María García-Alberca, Jose, additional, Luís Royo, Jose, additional, Rodriguez-Rodriguez, Eloy, additional, Soininen, Hilkka, additional, Heikkinen, Sami, additional, de Mendonça, Alexandre, additional, Mehrabian, Shima, additional, Traykov, Latchezar, additional, Hort, Jakub, additional, Vyhnalek, Martin, additional, Rasmussen, Katrine Laura, additional, Qvist Thomassen, Jesper, additional, Pijnenburg, Yolande A.L., additional, Holstege, Henne, additional, van Swieten, John, additional, Ramakers, Inez, additional, Verhey, Frans, additional, van der Lugt, Aad, additional, Scheltens, Philip, additional, Ortega-Rojas, Jenny, additional, Concha Mera, Ana Gabriela, additional, Mahecha, Maria F., additional, Pardo, Rodrogo, additional, Arboleda, Gonzalo, additional, Graff, Caroline, additional, Papenberg, Goran, additional, Giedraitis, Vilmantas, additional, Boland, Anne, additional, Deleuze, Jean-François, additional, Armando de Marco, Luiz, additional, Nunes de Moraes, Edgar, additional, de Viana, Bernardo, additional, Túlio Gualberto Cintra, Marco, additional, Grsiwold, Anthony, additional, Forund, Tatiana, additional, Cruchaga, Carlos, additional, Haines, Jonathan, additional, Farrer, Lindsay, additional, DeStefano, Anita, additional, Wijsman, Ellen, additional, Mayeux, Richard, additional, Pericak-Vance, Margaret, additional, Kunkle, Brian, additional, Goate, Alison, additional, Schellenberg, Gerard D., additional, Vardarajan, Badri, additional, Wang, Li-San, additional, Leung, Yuk Yee, additional, Dalgard, Clifton, additional, Nicolas, Gael, additional, Wallon, David, additional, Dufouil, Carole, additional, Pasquier, Florence, additional, Hanon, Olivier, additional, Debette, Stéphanie, additional, Grünblatt, Edna, additional, Popp, Julius, additional, Angel, Bárbara, additional, Golger, Sergio, additional, Victoria Chacon, Maria, additional, Aranguiz, Rafael, additional, Orellana, Paulina, additional, Slachevsky, Andrea, additional, Gonzalez-Billault, Christian, additional, Albala, Cecilia, additional, Fuentes, Patricio, additional, Porter, Tenielle, additional, Laws, Simon M, additional, Sachdev, Perminder, additional, Mather, Karen, additional, Hauger, Richard L., additional, Merritt, Victoria, additional, Panizzon, Matthew, additional, Zhang, Rui, additional, Gaziano, Michael, additional, Ghidoni, Roberta, additional, Galimberti, Daniela, additional, Arosio, Beatrice, additional, Mecocci, Patrizia, additional, Solfrizzi, Vincenzo, additional, Parnetti, Lucilla, additional, Squassina, Alessio, additional, Tremolizzo, Lucio, additional, Borroni, Barbara, additional, Nacmias, Benedetta, additional, Caffarra, Paolo, additional, Seripa, Davide, additional, Rainero, Innocenzo, additional, Daniele, Antonio, additional, Piras, Fabrizio, additional, Miyashita, Akinori, additional, Hara, Norikazu, additional, Ozaki, Kouichi, additional, Niida, Shumpei, additional, Williams, Julie, additional, Masullo, Carlo, additional, Amouyel, Philippe, additional, Preux, Pierre-Marie, additional, Mbelesso, Pascal, additional, Bandzouzi, Bébène, additional, Saykin, Andy, additional, Jessen, Frank, additional, Kehoe, Patrick, additional, Van Duijn, Cornelia, additional, Gim, Jungsoo, additional, Ben Salem, Nesrine, additional, Frikke-Schmidt, Ruth, additional, Cherni, Lofti, additional, Greicius, Michael D., additional, Tsolaki, Magda, additional, Sánchez-Juan, Pascual, additional, Romano Silva, Marco Aurélio, additional, Sleegers, Kristel, additional, Ingelsson, Martin, additional, Dartigues, Jean-François, additional, Seshadri, Sudha, additional, Rossi, Giacomina, additional, Morelli, Laura, additional, Hiltunen, Mikko, additional, Sims, Rebecca, additional, van der Flier, Wiesje, additional, Andreassen, Ole, additional, Arboleda, Humberto, additional, Escott-Price, Valentina, additional, Ruiz, Agustín, additional, Lee, Kun Ho, additional, Ikeuchi, Takeshi, additional, Ramirez, Alfredo, additional, Logue, Mark, additional, and Lambert, Jean-Charles, additional

Published
2023
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25. Author Correction: Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores

Author

de Rojas, Itziar, Moreno-Grau, Sonia, Tesi, Niccolo, Grenier-Boley, Benjamin, Andrade, Victor, Jansen, Iris E., Pedersen, Nancy L., Stringa, Najada, Zettergren, Anna, Hernández, Isabel, Antúnez, Carmen, Antonell, Anna, Tankard, Rick M., Bis, Joshua C., Sims, Rebecca, Bellenguez, Céline, Quintela, Inés, González-Perez, Antonio, Calero, Miguel, Macías, Juan, Blesa, Rafael, Cervera-Carles, Laura, Menéndez-González, Manuel, Royo, Jose Luís, Moreno, Fermin, Huerto Vilas, Raquel, Baquero, Miquel, Diez-Fairen, Mónica, Lage, Carmen, García-González, Pablo, Valero, Sergi, Ullgren, Abbe, Naj, Adam C., Lemstra, Afina W., Benussi, Alberto, Rábano, Alberto, Padovani, Alessandro, Squassina, Alessio, de Mendonça, Alexandre, Arias Pastor, Alfonso, Kok, Almar A. L., Meggy, Alun, Pastor, Ana Belén, Espinosa, Ana, Corma-Gómez, Anaïs, Sanabria, Ángela, DeStefano, Anita L., Schneider, Anja, Haapasalo, Annakaisa, Kinhult Ståhlbom, Anne, Tybjærg-Hansen, Anne, Hartmann, Annette M., Spottke, Annika, Corbatón-Anchuelo, Arturo, Rongve, Arvid, Borroni, Barbara, Arosio, Beatrice, Nacmias, Benedetta, Nordestgaard, Børge G., Kunkle, Brian W., Charbonnier, Camille, Masullo, Carlo, Martínez Rodríguez, Carmen, Muñoz-Fernandez, Carmen, Dufouil, Carole, Graff, Caroline, Ferreira, Catarina B., Chillotti, Caterina, Reynolds, Chandra A., Fenoglio, Chiara, Van Broeckhoven, Christine, Clark, Christopher, Pisanu, Claudia, Satizabal, Claudia L., Holmes, Clive, Buiza-Rueda, Dolores, Aarsland, Dag, Rujescu, Dan, Alcolea, Daniel, Galimberti, Daniela, Wallon, David, Seripa, Davide, Grünblatt, Edna, Dardiotis, Efthimios, Düzel, Emrah, Scarpini, Elio, Conti, Elisa, Rubino, Elisa, Gelpi, Ellen, Rodriguez-Rodriguez, Eloy, Duron, Emmanuelle, Boerwinkle, Eric, Ferri, Evelyn, Tagliavini, Fabrizio, Küçükali, Fahri, Pasquier, Florence, Sanchez-Garcia, Florentino, Mangialasche, Francesca, Jessen, Frank, Nicolas, Gaël, Selbæk, Geir, Ortega, Gemma, Chêne, Geneviève, Hadjigeorgiou, Georgios, Rossi, Giacomina, Spalletta, Gianfranco, Giaccone, Giorgio, Grande, Giulia, Binetti, Giuliano, Papenberg, Goran, Hampel, Harald, Bailly, Henri, Zetterberg, Henrik, Soininen, Hilkka, Karlsson, Ida K., Alvarez, Ignacio, Appollonio, Ildebrando, Giegling, Ina, Skoog, Ingmar, Saltvedt, Ingvild, Rainero, Innocenzo, Rosas Allende, Irene, Hort, Jakub, Diehl-Schmid, Janine, Van Dongen, Jasper, Vidal, Jean-Sebastien, Lehtisalo, Jenni, Wiltfang, Jens, Thomassen, Jesper Qvist, Kornhuber, Johannes, Haines, Jonathan L., Vogelgsang, Jonathan, Pineda, Juan A., Fortea, Juan, Popp, Julius, Deckert, Jürgen, Buerger, Katharina, Morgan, Kevin, Fließbach, Klaus, Sleegers, Kristel, Molina-Porcel, Laura, Kilander, Lena, Weinhold, Leonie, Farrer, Lindsay A., Wang, Li-San, Kleineidam, Luca, Farotti, Lucia, Parnetti, Lucilla, Tremolizzo, Lucio, Hausner, Lucrezia, Benussi, Luisa, Froelich, Lutz, Ikram, M. Arfan, Deniz-Naranjo, M. Candida, Tsolaki, Magda, Rosende-Roca, Maitée, Löwenmark, Malin, Hulsman, Marc, Spallazzi, Marco, Pericak-Vance, Margaret A., Esiri, Margaret, Bernal Sánchez-Arjona, María, Dalmasso, Maria Carolina, Martínez-Larrad, María Teresa, Arcaro, Marina, Nöthen, Markus M., Fernández-Fuertes, Marta, Dichgans, Martin, Ingelsson, Martin, Herrmann, Martin J., Scherer, Martin, Vyhnalek, Martin, Kosmidis, Mary H., Yannakoulia, Mary, Schmid, Matthias, Ewers, Michael, Heneka, Michael T., Wagner, Michael, Scamosci, Michela, Kivipelto, Miia, Hiltunen, Mikko, Zulaica, Miren, Alegret, Montserrat, Fornage, Myriam, Roberto, Natalia, van Schoor, Natasja M., Seidu, Nazib M., Banaj, Nerisa, Armstrong, Nicola J., Scarmeas, Nikolaos, Scherbaum, Norbert, Goldhardt, Oliver, Hanon, Oliver, Peters, Oliver, Skrobot, Olivia Anna, Quenez, Olivier, Lerch, Ondrej, Bossù, Paola, Caffarra, Paolo, Dionigi Rossi, Paolo, Sakka, Paraskevi, Mecocci, Patrizia, Hoffmann, Per, Holmans, Peter A., Fischer, Peter, Riederer, Peter, Yang, Qiong, Marshall, Rachel, Kalaria, Rajesh N., Mayeux, Richard, Vandenberghe, Rik, Cecchetti, Roberta, Ghidoni, Roberta, Frikke-Schmidt, Ruth, Sorbi, Sandro, Hägg, Sara, Engelborghs, Sebastiaan, Helisalmi, Seppo, Botne Sando, Sigrid, Kern, Silke, Archetti, Silvana, Boschi, Silvia, Fostinelli, Silvia, Gil, Silvia, Mendoza, Silvia, Mead, Simon, Ciccone, Simona, Djurovic, Srdjan, Heilmann-Heimbach, Stefanie, Riedel-Heller, Steffi, Kuulasmaa, Teemu, del Ser, Teodoro, Lebouvier, Thibaud, Polak, Thomas, Ngandu, Tiia, Grimmer, Timo, Bessi, Valentina, Escott-Price, Valentina, Giedraitis, Vilmantas, Deramecourt, Vincent, Maier, Wolfgang, Jian, Xueqiu, Pijnenburg, Yolande A. L., Smith, A. David, Saenz, Aldo, Bizzarro, Alessandra, Lauria, Alessandra, Vacca, Alessandro, Solomon, Alina, Anastasiou, Anna, Richardson, Anna, Boland, Anne, Koivisto, Anne, Daniele, Antonio, Greco, Antonio, Marianthi, Arnaoutoglou, McGuinness, Bernadette, Fin, Bertrand, Ferrari, Camilla, Custodero, Carlo, Ferrarese, Carlo, Ingino, Carlos, Mangone, Carlos, Reyes Toso, Carlos, Martínez, Carmen, Cuesta, Carolina, Muchnik, Carolina, Joachim, Catharine, Ortiz, Cecilia, Besse, Céline, Johansson, Charlotte, Zoia, Chiara Paola, Laske, Christoph, Anastasiou, Costas, Palacio, Dana Lis, Politis, Daniel G., Janowitz, Daniel, Craig, David, Mann, David M., Neary, David, Jürgen, Deckert, Daian, Delphine, Belezhanska, Diyana, Kohler, Eduardo, Castaño, Eduardo M., Koutsouraki, Effrosyni, Chipi, Elena, De Roeck, Ellen, Costantini, Emanuele, Vardy, Emma R. L. C., Piras, Fabrizio, Roveta, Fausto, Piras, Federica, Prestia, Federico Ariel, Assogna, Francesca, Salani, Francesca, Sala, Gessica, Lacidogna, Giordano, Novack, Gisela, Wilcock, Gordon, Thonberg, Håkan, Kölsch, Heike, Weber, Heike, Boecker, Henning, Etchepareborda, Ignacio, Piaceri, Irene, Tuomilehto, Jaakko, Lindström, Jaana, Laczo, Jan, Johnston, Janet, Deleuze, Jean-François, Harris, Jenny, Schott, Jonathan M., Priller, Josef, Bacha, Juan Ignacio, Snowden, Julie, Lisso, Julieta, Mihova, Kalina Yonkova, Traykov, Latchezar, Morelli, Laura, Brusco, Luis Ignacio, Rainer, Malik, Takalo, Mari, Bjerke, Maria, Del Zompo, Maria, Serpente, Maria, Sanchez Abalos, Mariana, Rios, Mario, Peltonen, Markku, Herrman, Martin J., Kohler, Matias, Rojo, Matias, Jones, Matthew, Orsini, Michela, Medel, Nancy, Olivar, Natividad, Fox, Nick C., Salvadori, Nicola, Hooper, Nigel M., Galeano, Pablo, Solis, Patricia, Bastiani, Patrizia, Passmore, Peter, Heun, Reinhard, Antikainen, Riitta, Olaso, Robert, Perneczky, Robert, Germani, Sandra, López-García, Sara, Love, Seth, Mehrabian, Shima, Bagnoli, Silvia, Kochen, Silvia, Andreoni, Simona, Teipel, Stefan, Todd, Stephen, Pickering-Brown, Stuart, Natunen, Teemu, Tegos, Thomas, Laatikainen, Tiina, Strandberg, Timo, Polvikoski, Tuomo M., Matoska, Vaclav, Ciullo, Valentina, Cores, Valeria, Solfrizzi, Vincenzo, Lisetti, Viviana, Sevillano, Zulma, Abdelnour, C., Aguilera, N., Alarcon, E., Alegret, M., Benaque, A., Boada, M., Buendia, M., Cañabate, P., Carracedo, A., de Rojas, I., Diego, S., Espinosa, A., Gailhajenet, A., García-González, P., Gil, S., Guitart, M., González-Pérez, A., Hernández, I., Ibarria, M., Lafuente, A., Macias, J., Maroñas, O., Martín, E., Martínez, M.T., Marquié, M., Mauleón, A., Montrreal, L., Moreno-Grau, S., Moreno, M., Orellana, A., Ortega, G., Pancho, A., Pelejá, E., Pérez-Cordon, A., Pineda, J.A., Preckler, S., Quintela, I., Real, L.M., Rosende-Roca, M., Ruiz, A., Sáez, M.E., Sanabria, A., Serrano-Rios, M., Sotolongo-Grau, O., Tárraga, L., Valero, S., Vargas, L., Adarmes-Gómez, A.D., Alarcón-Martín, E., Alonso, M.D., Álvarez, I., Álvarez, V., Amer-Ferrer, G., Antequera, M., Antúnez, C., Baquero, M., Bernal, M., Blesa, R., Bullido, M.J., Burguera, J.A., Calero, M., Carrillo, F., Carrión-Claro, M., Casajeros, M.J., Clarimón, J., Cruz-Gamero, J.M., de Pancorbo, M.M., del Ser, T., Diez-Fairen, M., Escuela, R., Garrote-Espina, L., Fortea, J., Franco-Macías, E., Frank-García, A., Garcia Madrona, S., Gómez-Garre, P., Hevilla, S., Jesús, S., Labrador Espinosa, M.A., Lage, C., Legaz, A., Lleó, A., Lopez de Munain, A., López-García, S., Macias-García, D., Manzanares, S., Marín, M., Marín-Muñoz, J., Marín, T., Martín Montes, A., Martínez, B., Martínez, C., Martínez, V., Martínez-Lage Álvarez, P., Medina, M., Mendioroz Iriarte, M., Menéndez-González, M., Mir, P., Molinuevo, J.L., Pastor, P., Pérez Tur, J., Periñán-Tocino, T., Pineda-Sanchez, R., Piñol-Ripoll, G., Rábano, A., Real de Asúa, D., Rodrigo, S., Rodríguez-Rodríguez, E., Royo, J.L., Sanchez del Valle Díaz, R., Sánchez-Juan, P., Sastre, I., Vicente, M.P., Vigo-Ortega, R., Vivancos, L., Macleod, C., McCracken, C., Brayne, Carol, Bresner, Catherine, Grozeva, Detelina, Bellou, Eftychia, Sommerville, Ewen W., Matthews, F., Leonenko, Ganna, Menzies, Georgina, Windle, Gill, Harwood, Janet, Phillips, Judith, Bennett, K., Luckuck, Lauren, Clare, Linda, Woods, Robert, Saad, Salha, Burholt, Vanessa, Kehoe, Patrick Gavin, Garcia-Ribas, Guillermo, Sánchez-Juan, Pascual, Pastor, Pau, Pérez-Tur, Jordi, Piñol-Ripoll, Gerard, Lopez de Munain, Adolfo, García-Alberca, Jose María, Bullido, María J., Álvarez, Victoria, Lleó, Alberto, Real, Luis M., Mir, Pablo, Medina, Miguel, Scheltens, Philip, Holstege, Henne, Marquié, Marta, Sáez, María Eugenia, Carracedo, Ángel, Amouyel, Philippe, Schellenberg, Gerard D., Williams, Julie, Seshadri, Sudha, van Duijn, Cornelia M., Mather, Karen A., Sánchez-Valle, Raquel, Serrano-Ríos, Manuel, Orellana, Adelina, Tárraga, Lluís, Blennow, Kaj, Huisman, Martijn, Andreassen, Ole A., Posthuma, Danielle, Clarimón, Jordi, Boada, Mercè, van der Flier, Wiesje M., Ramirez, Alfredo, Lambert, Jean-Charles, van der Lee, Sven J., Ruiz, Agustín, Smith, A David, Saenz, Aldo, Bizzarro, Alessandra, Lauria, Alessandra, Vacca, Alessandro, Solomon, Alina, Anastasiou, Anna, Richardson, Anna, Boland, Anne, Koivisto, Anne, Daniele, Antonio, Greco, Antonio, Marianthi, Arnaoutoglou, McGuinness, Bernadette, Fin, Bertrand, Ferrari, Camilla, Custodero, Carlo, Ferrarese, Carlo, Ingino, Carlos, Mangone, Carlos, Reyes Toso, Carlos, Martínez, Carmen, Cuesta, Carolina, Muchnik, Carolina, Joachim, Catharine, Ortiz, Cecilia, Besse, Céline, Johansson, Charlotte, Zoia, Chiara Paola, Laske, Christoph, Anastasiou, Costas, Palacio, Dana Lis, Politis, Daniel G, Janowitz, Daniel, Craig, David, Mann, David M, Neary, David, Jürgen, Deckert, Daian, Delphine, Belezhanska, Diyana, Kohler, Eduardo, Castaño, Eduardo M, Koutsouraki, Effrosyni, Chipi, Elena, De Roeck, Ellen, Costantini, Emanuele, Vardy, Emma R L C, Piras, Fabrizio, Roveta, Fausto, Piras, Federica, Prestia, Federico Ariel, Assogna, Francesca, Salani, Francesca, Sala, Gessica, Lacidogna, Giordano, Novack, Gisela, Wilcock, Gordon, Thonberg, Håkan, Kölsch, Heike, Weber, Heike, Boecker, Henning, Etchepareborda, Ignacio, Piaceri, Irene, Tuomilehto, Jaakko, Lindström, Jaana, Laczo, Jan, Johnston, Janet, Deleuze, Jean-François, Harris, Jenny, Schott, Jonathan M, Priller, Josef, Bacha, Juan Ignacio, Snowden, Julie, Lisso, Julieta, Mihova, Kalina Yonkova, Traykov, Latchezar, Morelli, Laura, Brusco, Luis Ignacio, Rainer, Malik, Takalo, Mari, Bjerke, Maria, Del Zompo, Maria, Serpente, Maria, Sanchez Abalos, Mariana, Rios, Mario, Peltonen, Markku, Herrman, Martin J, Kohler, Matias, Rojo, Matias, Jones, Matthew, Orsini, Michela, Medel, Nancy, Olivar, Natividad, Fox, Nick C, Salvadori, Nicola, Hooper, Nigel M, Galeano, Pablo, Solis, Patricia, Bastiani, Patrizia, Passmore, Peter, Heun, Reinhard, Antikainen, Riitta, Olaso, Robert, Perneczky, Robert, Germani, Sandra, López-García, Sara, Love, Seth, Mehrabian, Shima, Bagnoli, Silvia, Kochen, Silvia, Andreoni, Simona, Teipel, Stefan, Todd, Stephen, Pickering-Brown, Stuart, Natunen, Teemu, Tegos, Thomas, Laatikainen, Tiina, Strandberg, Timo, Polvikoski, Tuomo M, Matoska, Vaclav, Ciullo, Valentina, Cores, Valeria, Solfrizzi, Vincenzo, Lisetti, Viviana, Sevillano, Zulma, Abdelnour, C., Aguilera, N., Alarcon, E., Alegret, M., Benaque, A., Boada, M., Buendia, M., Cañabate, P., Carracedo, A., Corbatón-Anchuelo, A., de Rojas, I., Diego, S., Espinosa, A., Gailhajenet, A., García-González, P., Gil, S., Guitart, M., González-Pérez, A., Hernández, I., Ibarria, M., Lafuente, A., Macias, J., Maroñas, O., Martín, E., Martínez, M. T., Marquié, M., Mauleón, A., Montrreal, L., Moreno-Grau, S., Moreno, M., Orellana, A., Ortega, G., Pancho, A., Pelejá, E., Pérez-Cordon, A., Pineda, J. A., Preckler, S., Quintela, I., Real, L. M., Rosende-Roca, M., Ruiz, A., Sáez, M. E., Sanabria, A., Serrano-Rios, M., Sotolongo-Grau, O., Tárraga, L., Valero, S., Vargas, L., Adarmes-Gómez, A. D., Alarcón-Martín, E., Alonso, M. D., Álvarez, I., Álvarez, V., Amer-Ferrer, G., Antequera, M., Antúnez, C., Baquero, M., Bernal, M., Blesa, R., Buiza-Rueda, D., Bullido, M. J., Burguera, J. A., Calero, M., Carrillo, F., Carrión-Claro, M., Casajeros, M. J., Clarimón, J., Cruz-Gamero, J. M., de Pancorbo, M. M., Del Ser, T., Diez-Fairen, M., Escuela, R., Garrote-Espina, L., Fortea, J., Franco-Macías, E., Frank-García, A., García-Alberca, J. M., Garcia Madrona, S., Garcia-Ribas, G., Gómez-Garre, P., Hevilla, S., Jesús, S., Labrador Espinosa, M. A., Lage, C., Legaz, A., Lleó, A., Lopez de Munain, A., López-García, S., Macias-García, D., Manzanares, S., Marín, M., Marín-Muñoz, J., Marín, T., Martín Montes, A., Martínez, B., Martínez, C., Martínez, V., Martínez-Lage Álvarez, P., Medina, M., Mendioroz Iriarte, M., Menéndez-González, M., Mir, P., Molinuevo, J. L., Pastor, P., Pérez Tur, J., Periñán-Tocino, T., Pineda-Sanchez, R., Piñol-Ripoll, G., Rábano, A., Real de Asúa, D., Rodrigo, S., Rodríguez-Rodríguez, E., Royo, J. L., Sanchez Del Valle Díaz, R., Sánchez-Juan, P., Sastre, I., Vicente, M. P., Vigo-Ortega, R., Vivancos, L., Macleod, C., McCracken, C., Brayne, Carol, Bresner, Catherine, Grozeva, Detelina, Bellou, Eftychia, Sommerville, Ewen W, Matthews, F., Leonenko, Ganna, Menzies, Georgina, Windle, Gill, Harwood, Janet, Phillips, Judith, Bennett, K., Luckuck, Lauren, Clare, Linda, Woods, Robert, Saad, Salha, Burholt, Vanessa, Rongve, Arvid, Brussels Heritage Lab, Clinical sciences, Neuroprotection & Neuromodulation, and Neurology

Subjects
polygenic risk scores, Multidisciplinary, Common variants, Neuroscience(all), neurology, Medizin, General Physics and Astronomy, ddc:500, General Chemistry, Alzheimer's disease, General Biochemistry, Genetics and Molecular Biology, RISK STRATIFICATION
Abstract

The original version of this Article omitted from the author list the 212th author Patrizia Mecocci, who is from the Institute of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy. Consequently, the “Sample Contribution” section of Author Contributions was updated to add “P.M” between “P.D.” and “R.C.”. Additionally, the original version of this Article contained the incorrect affiliation for author Patrick Gavin Kehoe, which incorrectly read “German Center for Neurodegenerative Diseases (DZNE), Berlin, Germany”. The correct version replaces this affiliation with “Bristol Medical School (THS), University of Bristol, Southmead Hospital, Bristol, UK”. This has been corrected in both the PDF and HTML versions of the Article. CA extern

Published
2023
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31. Transethnic meta-analysis of rare coding variants in PLCG2, ABI3, and TREM2 supports their general contribution to Alzheimer’s disease

Author

Dalmasso, Maria Carolina, Brusco, Luis Ignacio, Olivar, Natividad, Muchnik, Carolina, Hanses, Claudia, Milz, Esther, Becker, Julian, Heilmann-Heimbach, Stefanie, Hoffmann, Per, Prestia, Federico A., Galeano, Pablo, Avalos, Mariana Soledad Sanchez, Martinez, Luis Eduardo, Carulla, Mariana Estela, Azurmendi, Pablo Javier, Liberczuk, Cynthia, Fezza, Cristina, Sampaño, Marcelo, Fierens, Maria, Jemar, Guillermo, Solis, Patricia, Medel, Nancy, Lisso, Julieta, Sevillano, Zulma, Bosco, Paolo, Bossù, Paola, Spalletta, Gianfranco, Galimberti, Daniela, Mancuso, Michelangelo, Nacmias, Benedetta, Sorbi, Sandro, Mecocci, Patrizia, Pilotto, Alberto, Caffarra, Paolo, Panza, Francesco, Bullido, Maria, Clarimon, Jordi, Sánchez-Juan, Pascual, Coto, Eliecer, Sanchez-Garcia, Florentino, Graff, Caroline, Ingelsson, Martin, Bellenguez, Céline, Castaño, Eduardo Miguel, Kairiyama, Claudia, Politis, Daniel Gustavo, Kochen, Silvia, Scaro, Horacio, Maier, Wolfgang, Jessen, Frank, Mangone, Carlos Alberto, Lambert, Jean-Charles, Morelli, Laura, and Ramirez, Alfredo

Published
2019
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32. The Impact of a Geographic Technologies Professional Development Institute on Middle Eastern and North African Teachers

Author

Benimmas, Aicha, Kerski, Joseph, and Solis, Patricia

Abstract

Basic education in the Middle East and North Africa (MENA) seems to be characterized by lecture methods of instruction, a lack of interdisciplinary approaches and a disconnection with local community problems. During 2008, a "My Community, Our Earth" (MyCOE) workshop was organized in the MENA region and involved teachers of geography, math and science. It aimed to promote and support the use of geographic methods and technologies, including Geographic Information Systems (GIS) and Global Positioning Systems (GPS), regarding sustainable development topics as a way to improve primary and secondary teaching and learning through an interdisciplinary approach and connection to local issues. These subjects were integrated to a perspective based on spatial thinking, spatial analysis, active learning and problem solving on a variety of regional and local issues. This article explores the impact that the MyCOE workshop may have on participants' learning. Preworkshop and postworkshop questionnaires were administered, and the analysis of qualitative and quantitative data shows that the respondents' expertise was reinforced and that they learned to use geographic technologies. In addition, the MyCOE workshop resulted in the development of a more concrete vision among participants of what basic math and science education could be in Arab nations, by using geographic learning as a framework for integrated education. (Contains 2 tables and 9 figures.)

Published
2011
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34. Water as Rural Heritage: Reworking Modernity through Resource Conflict in Edwards County, Kansas

Author

Solis, Patricia

Abstract

Conflicts over changing uses of natural resources are familiar within communities of the Western US and are usually resolved through legal processes. This paper analyzes resource conflict through juxtaposing impact analyses often used in their juridical resolution with discourse analyses of affected rural communities. The purchase of property by a mid-size city in central Kansas to transfer water from a ranch along the Arkansas River in rural Edwards County evoked expressions of water as "heritage", functioning as a placed-based, defensive ideology. Plans for the first rural-to-urban interbasin water transfer in Kansas failed to materialize into a legal proposal because of the controversy that ensued, despite the fact that impact analyses suggested little material effect. In light of decades of decline due to economic frustration, political marginalization, and demographic outmigration, rural communities maintain the symbols of nature in order to legitimate their struggle against what are seen as intrusive, destructive elements of changing uses of natural resources.

Published
2005
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35. Supplemental Material - Deploying geospatial visualization dashboards to combat the socioeconomic impacts of COVID-19

Author

Praharaj, Sarbeswar, Solis, Patricia, and Wentz, Elizabeth A

Subjects
FOS: Social and economic geography, Geography, 120599 Urban and Regional Planning not elsewhere classified
Abstract

Supplementary Material for Deploying geospatial visualization dashboards to combat the socioeconomic impacts of COVID-19 by Sarbeswar Praharaj, Patricia Solis, and Elizabeth A Wentz in Environment and Planning B: Urban Analytics and City Science.

Published
2022
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40. Dementia in Latin America: Paving the way toward a regional action plan

Author

Parra, Mario Alfredo, primary, Baez, Sandra, additional, Sedeño, Lucas, additional, Gonzalez Campo, Cecilia, additional, Santamaría‐García, Hernando, additional, Aprahamian, Ivan, additional, Bertolucci, Paulo HF, additional, Bustin, Julian, additional, Camargos Bicalho, Maria Aparecida, additional, Cano‐Gutierrez, Carlos, additional, Caramelli, Paulo, additional, Chaves, Marcia L. F., additional, Cogram, Patricia, additional, Beber, Bárbara Costa, additional, Court, Felipe A., additional, de Souza, Leonardo Cruz, additional, Custodio, Nilton, additional, Damian, Andres, additional, de la Cruz, Myriam, additional, Diehl Rodriguez, Roberta, additional, Brucki, Sonia Maria Dozzi, additional, Fajersztajn, Lais, additional, Farías, Gonzalo A., additional, De Felice, Fernanda G., additional, Ferrari, Raffaele, additional, de Oliveira, Fabricio Ferreira, additional, Ferreira, Sergio T., additional, Ferretti, Ceres, additional, Figueredo Balthazar, Marcio Luiz, additional, Ferreira Frota, Norberto Anizio, additional, Fuentes, Patricio, additional, García, Adolfo M., additional, Garcia, Patricia J., additional, de Gobbi Porto, Fábio Henrique, additional, Duque Peñailillo, Lissette, additional, Engler, Henry Willy, additional, Maier, Irene, additional, Mata, Ignacio F., additional, Gonzalez‐Billault, Christian, additional, Lopez, Oscar L., additional, Morelli, Laura, additional, Nitrini, Ricardo, additional, Quiroz, Yakeel T., additional, Guerrero Barragan, Alejandra, additional, Huepe, David, additional, Pio, Fabricio Joao, additional, Suemoto, Claudia Kimie, additional, Kochhann, Renata, additional, Kochen, Silvia, additional, Kumfor, Fiona, additional, Lanata, Serggio, additional, Miller, Bruce, additional, Mansur, Leticia Lessa, additional, Hosogi, Mirna Lie, additional, Lillo, Patricia, additional, Llibre Guerra, Jorge, additional, Lira, David, additional, Lopera, Francisco, additional, Comas, Adelina, additional, Avila‐Funes, José Alberto, additional, Sosa, Ana Luisa, additional, Ramos, Claudia, additional, Resende, Elisa de Paula França, additional, Snyder, Heather M., additional, Tarnanas, Ioannis, additional, Yokoyama, Jenifer, additional, Llibre, Juan, additional, Cardona, Juan Felipe, additional, Possin, Kate, additional, Kosik, Kenneth S., additional, Montesinos, Rosa, additional, Moguilner, Sebastian, additional, Solis, Patricia Cristina Lourdes, additional, Ferretti‐Rebustini, Renata Eloah de Lucena, additional, Ramirez, Jeronimo Martin, additional, Matallana, Diana, additional, Mbakile‐Mahlanza, Lingani, additional, Marques Ton, Alyne Mendonça, additional, Tavares, Ronnielly Melo, additional, Miotto, Eliane C, additional, Muniz‐Terrera, Graciela, additional, Muñoz‐Nevárez, Luis Arnoldo, additional, Orozco, David, additional, Okada de Oliveira, Maira, additional, Piguet, Olivier, additional, Pintado Caipa, Maritza, additional, Piña Escudero, Stefanie Danielle, additional, Schilling, Lucas Porcello, additional, Rodrigues Palmeira, André Luiz, additional, Yassuda, Mônica Sanches, additional, Santacruz‐Escudero, Jose Manuel, additional, Serafim, Rodrigo Bernardo, additional, Smid, Jerusa, additional, Slachevsky, Andrea, additional, Serrano, Cecilia, additional, Soto‐Añari, Marcio, additional, Takada, Leonel Tadao, additional, Grinberg, Lea Tenenholz, additional, Teixeira, Antonio Lucio, additional, Barbosa, Maira Tonidandel, additional, Trépel, Dominic, additional, and Ibanez, Agustin, additional

Published
2020
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41. Memory reconsolidation as a tool to endure encoding deficits in elderly

Author

Tassone, Leonela M., primary, Urreta Benítez, Facundo A., additional, Rochon, Delfina, additional, Martínez, Paula B., additional, Bonilla, Matias, additional, Leon, Candela S., additional, Muchnik, Carolina, additional, Solis, Patricia, additional, Medel, Nancy, additional, Kochen, Silvia, additional, Brusco, Luis I., additional, Moyano, Malen D., additional, and Forcato, Cecilia, additional

Published
2020
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45. Transethnic meta-analysis of rare coding variants in PLCG2, ABI3, and TREM2 supports their general contribution to Alzheimer's disease

Author

Carolina Dalmasso, Maria, Ignacio Brusco, Luis, Olivar, Natividad, Muchnik, Carolina, Hanses, Claudia, Milz, Esther, Becker, Julian, Heilmann-Heimbach, Stefanie, Hoffmann, Per, Prestia, Federico A., Galeano, Pablo, Sanchez Avalos, Mariana Soledad, Eduardo Martinez, Luis, Estela Carulla, Mariana, Javier Azurmendi, Pablo, Liberczuk, Cynthia, Fezza, Cristina, Sampano, Marcelo, Fierens, Maria, Jemar, Guillermo, Solis, Patricia, Medel, Nancy, Lisso, Julieta, Sevillano, Zulma, Bosco, Paolo, Bossu, Paola, Spalletta, Gianfranco, Galimberti, Daniela, Mancuso, Michelangelo, Nacmias, Benedetta, Sorbi, Sandro, Mecocci, Patrizia, Pilotto, Alberto, Caffarra, Paolo, Panza, Francesco, Bullido, Maria, Clarimon, Jordi, Sanchez-Juan, Pascual, Coto, Eliecer, Sanchez-Garcia, Florentino, Graff, Caroline, Ingelsson, Martin, Bellenguez, Celine, Miguel Castano, Eduardo, Kairiyama, Claudia, Gustavo Politis, Daniel, Kochen, Silvia, Scaro, Horacio, Maier, Wolfgang, Jessen, Frank, Alberto Mangone, Carlos, Lambert, Jean-Charles, Morelli, Laura, Ramirez, Alfredo, Carolina Dalmasso, Maria, Ignacio Brusco, Luis, Olivar, Natividad, Muchnik, Carolina, Hanses, Claudia, Milz, Esther, Becker, Julian, Heilmann-Heimbach, Stefanie, Hoffmann, Per, Prestia, Federico A., Galeano, Pablo, Sanchez Avalos, Mariana Soledad, Eduardo Martinez, Luis, Estela Carulla, Mariana, Javier Azurmendi, Pablo, Liberczuk, Cynthia, Fezza, Cristina, Sampano, Marcelo, Fierens, Maria, Jemar, Guillermo, Solis, Patricia, Medel, Nancy, Lisso, Julieta, Sevillano, Zulma, Bosco, Paolo, Bossu, Paola, Spalletta, Gianfranco, Galimberti, Daniela, Mancuso, Michelangelo, Nacmias, Benedetta, Sorbi, Sandro, Mecocci, Patrizia, Pilotto, Alberto, Caffarra, Paolo, Panza, Francesco, Bullido, Maria, Clarimon, Jordi, Sanchez-Juan, Pascual, Coto, Eliecer, Sanchez-Garcia, Florentino, Graff, Caroline, Ingelsson, Martin, Bellenguez, Celine, Miguel Castano, Eduardo, Kairiyama, Claudia, Gustavo Politis, Daniel, Kochen, Silvia, Scaro, Horacio, Maier, Wolfgang, Jessen, Frank, Alberto Mangone, Carlos, Lambert, Jean-Charles, Morelli, Laura, and Ramirez, Alfredo

Abstract

Rare coding variants in TREM2, PLCG2, and ABI3 were recently associated with the susceptibility to Alzheimer's disease (AD) in Caucasians. Frequencies and AD-associated effects of variants differ across ethnicities. To start filling the gap on AD genetics in South America and assess the impact of these variants across ethnicity, we studied these variants in Argentinian population in association with ancestry. TREM2 (rs143332484 and rs75932628), PLCG2 (rs72824905), and ABI3 (rs616338) were genotyped in 419 AD cases and 486 controls. Meta-analysis with European population was performed. Ancestry was estimated from genome-wide genotyping results. All variants show similar frequencies and odds ratios to those previously reported. Their association with AD reach statistical significance by meta-analysis. Although the Argentinian population is an admixture, variant carriers presented mainly Caucasian ancestry. Rare coding variants in TREM2, PLCG2, and ABI3 also modulate susceptibility to AD in populations from Argentina, and they may have a European heritage.

Published
2019
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46. Transethnic meta-analysis of rare coding variants in PLCG2, ABI3, and TREM2 supports their general contribution to Alzheimer’s disease

Author

International Society for Neurochemistry, Alexander von Humboldt Foundation, Agencia Nacional de Promoción Científica y Tecnológica (Argentina), Dalmaso, M. Carolina, Brusco, Luís I., Olivar, Natvidad, Muchnick, Carolina, Hanses, Claudia, Milz, Esther, Becker, Julian, Heilmann-Heimbach, Stefanie, Hoffmann, Per, Prestia, Federico A., Galeano, Pablo, Sánchez-Avalos, M. Soledad, Martínez, Luis E., Carulla, Mariana E., Azurmendi Pablo J., Liberczuk, Cynthia, Fezza, Cristina, Sampaño, Marcelo, Fierens, María, Jemar, Guillermo, Solis, Patricia, Medel, Nancy, Lisso, Julieta, Sevillano, Zulma, Bosco, Paolo, Bossu, Paola, Spalletta, Gianfranco, Galimberti, Daniela, Mancuso, Michelangelo, Nacmias, Benedetta, Sorbi, Sandro, Mecocci, Patrizia, Pilotto, Alberto, Caffarra, Paolo, Panza, Francesco, Bullido, María Jesús, Clarimón, Jordi, Sánchez-Juan, Pascual, Coto, Eliecer, Sánchez-García, Florentino, Graff, Caroline, Ingelsson, Martin, Bellenguez, Céline, Castaño, Eduardo M., Kairiyama, Claudia, Politis, Daniel G., Kochen, Silvia, Scaro, Horacio, Maier, Wolfgang, Jessen, Frank, Mangone, Carlos E., Lambert, Jean-Charles, Morelli, Laura, Ramírez, Alfredo, International Society for Neurochemistry, Alexander von Humboldt Foundation, Agencia Nacional de Promoción Científica y Tecnológica (Argentina), Dalmaso, M. Carolina, Brusco, Luís I., Olivar, Natvidad, Muchnick, Carolina, Hanses, Claudia, Milz, Esther, Becker, Julian, Heilmann-Heimbach, Stefanie, Hoffmann, Per, Prestia, Federico A., Galeano, Pablo, Sánchez-Avalos, M. Soledad, Martínez, Luis E., Carulla, Mariana E., Azurmendi Pablo J., Liberczuk, Cynthia, Fezza, Cristina, Sampaño, Marcelo, Fierens, María, Jemar, Guillermo, Solis, Patricia, Medel, Nancy, Lisso, Julieta, Sevillano, Zulma, Bosco, Paolo, Bossu, Paola, Spalletta, Gianfranco, Galimberti, Daniela, Mancuso, Michelangelo, Nacmias, Benedetta, Sorbi, Sandro, Mecocci, Patrizia, Pilotto, Alberto, Caffarra, Paolo, Panza, Francesco, Bullido, María Jesús, Clarimón, Jordi, Sánchez-Juan, Pascual, Coto, Eliecer, Sánchez-García, Florentino, Graff, Caroline, Ingelsson, Martin, Bellenguez, Céline, Castaño, Eduardo M., Kairiyama, Claudia, Politis, Daniel G., Kochen, Silvia, Scaro, Horacio, Maier, Wolfgang, Jessen, Frank, Mangone, Carlos E., Lambert, Jean-Charles, Morelli, Laura, and Ramírez, Alfredo

Abstract

Rare coding variants in TREM2, PLCG2, and ABI3 were recently associated with the susceptibility to Alzheimer’s disease (AD) in Caucasians. Frequencies and AD-associated effects of variants differ across ethnicities. To start filling the gap on AD genetics in South America and assess the impact of these variants across ethnicity, we studied these variants in Argentinian population in association with ancestry. TREM2 (rs143332484 and rs75932628), PLCG2 (rs72824905), and ABI3 (rs616338) were genotyped in 419 AD cases and 486 controls. Meta-analysis with European population was performed. Ancestry was estimated from genome-wide genotyping results. All variants show similar frequencies and odds ratios to those previously reported. Their association with AD reach statistical significance by meta-analysis. Although the Argentinian population is an admixture, variant carriers presented mainly Caucasian ancestry. Rare coding variants in TREM2, PLCG2, and ABI3 also modulate susceptibility to AD in populations from Argentina, and they may have a European heritage.

Published
2019

47. Desarrollo de los documentos para la implementación del sistema de gestión de seguridad y salud en el trabajo para la Empresa Alfa medica SM S.A.C. basada en la Ley N° 29783: Ley de Seguridad y Salud en el Trabajo

Author

Angulo Solis, Patricia Alexandra and Tanco Fernandez, Paúl

Subjects
Alfa Médica SM S.A.C, Sistema, Salud, purl.org/pe-repo/ocde/ford#2.11.02 [https], Seguridad
Abstract

El trabajo de investigación explora las consideraciones pertinentes para mejorar las condiciones de trabajo y brindar un ambiente seguro y saludable proponiendo el desarrollo de los para la implementación Sistema de Gestión de Seguridad y Salud en el Trabajo basado en las normas nacionales, Ley N° 29783, desarrollándose en Alfa Médica SM S.A.C, empresa dedicada a brindar servicios de salud ocupacional en el departamento de Arequipa. El concepto de Seguridad y Salud, día tras día toma más fuerza, y son cada vez más las empresas que se concientizan de la importancia que tiene el talento humano como pilar fundamental hacia el logro de objetivos y metas en el desarrollo institucional. La empresa “Alfa Médica SM S.A.C.” no es la excepción, por lo cual busca desarrollar un Sistema de Gestión de Seguridad y Salud, que de manera integral que genere las políticas necesarias para brindarle a todos sus colaboradores las garantías y herramientas que permitan un desarrollo personal y colectivo de manera idónea en función de un objetivo común, así como adecuarse a los requerimientos de la Ley mencionada. Este trabajo de investigación consta de tres partes, cada una de los cuales aborda diferentes aspectos. En la Primera Parte, se presenta la metodología de la investigación de la presente tesis. En la Segunda Parte, se detalla el marco conceptual vigente en materia de Seguridad y Salud en el Trabajo. En la Tercera Parte, se efectúa la descripción de la empresa, realizándose un diagnóstico inicial de la empresa en materia de Seguridad y Salud, se propone la implentación del Sistema de Gestión de Seguridad y Salud en el Trabajo a partir del diagnóstico inicial, considerando los requisitos de la Ley N° 29783 y su Reglamento el Decreto Supremo N° 005-2012-TR y modificatorias. Finalmente, los resultados se muestran en las conclusiones y recomendaciones. Se espera que la presente sirva de referencia para otras empresas que deseen adecuarse a los requisitos vigentes de la Ley N° 29783 y sus modificatorias. Tesis

Published
2018

48. Reconocimiento emocional auditivo y visual en pacientes con epilepsia: protocolo de estudio y resultados preliminares en una población normal autóctona

Author

Fernandez Lima, Monica Lorena, Scévola, Maria Laura, Oddo, Silvia Andrea, Giagante, Brenda, Solis, Patricia Cristina Lourdes, Kochen, Sara Silvia, D`alessio, Luciana, Kochen, Sara Silvia, D`alessio, Luciana, and Gonzalez, Paula Natalia

Subjects
VISUO AUDITIVOS, RECONOCIMIENTO, ESTIMULOS, purl.org/becyt/ford/3.2 [https], purl.org/becyt/ford/3 [https], EMOCIONES
Abstract

El reconocimiento emocional (RE) cumple un rol esencial en la conducta y en la cognición social, y el complejo hipocampo-amigdalino ha sido involucrado en esta función. La epilepsia de lóbulo temporal, forma más frecuente de epilepsia, compromete estas estructuras, lo cual pude afectar el RE. El objetivo de este estudio es determinar el rendimiento en el RE en una población autóctona como primera etapa, para luego comparar, a modo de grupo control, con una población de pacientes con epilepsia del lóbulo temporal resistente al tratamiento farmacológico (ELTR). Se determinó el RE mediante estímulos visuales tomados del set “Fotografías de emociones faciales” (Ekman&Friesen, 1976) y estímulos auditivos tomados del set “Montreal Affective Voices” (Belin, Fillion-Bilodeau, & Gosselin, 2008). En ambos casos, las categorías emocionales de los estímulos presentados fueron: felicidad, enojo, tristeza, miedo, asco, sorpresa, neutro. Los análisis estadísticos efectuados fueron a prueba de normalidad y el análisis de frecuencias. Se incluyeron 24 controles sanos (13 mujeres, 11 hombres; edad media: 37,21 +/- 13 años). El porcentaje de aciertos fue similar tanto con estímulos auditivos como visuales, excepto para la sorpresa, que fue reconocida mejor con los estímulos visuales, y para la tristeza y el neutro, que fueron reconocidos mejor con los auditivos. En este trabajo se presentan resultados del reconocimiento emocional en población autóctona de la República Argentina. El estudio de estas alteraciones en los pacientes con ELTR nos permitirá determinar la existencia de una correlación con las alteraciones en la conducta y en la cognición social observadas en estos pacientes. Fil: Fernandez Lima, Monica Lorena. Universidad Nacional Arturo Jauretche. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos. Provincia de Buenos Aires. Ministerio de Salud. Hospital Alta Complejidad en Red El Cruce Dr. Néstor Carlos Kirchner Samic. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos; Argentina Fil: Scévola, Maria Laura. Universidad Nacional Arturo Jauretche. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos. Provincia de Buenos Aires. Ministerio de Salud. Hospital Alta Complejidad en Red El Cruce Dr. Néstor Carlos Kirchner Samic. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos; Argentina Fil: Oddo, Silvia Andrea. Universidad Nacional Arturo Jauretche. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos. Provincia de Buenos Aires. Ministerio de Salud. Hospital Alta Complejidad en Red El Cruce Dr. Néstor Carlos Kirchner Samic. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos; Argentina Fil: Giagante, Brenda. Universidad Nacional Arturo Jauretche. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos. Provincia de Buenos Aires. Ministerio de Salud. Hospital Alta Complejidad en Red El Cruce Dr. Néstor Carlos Kirchner Samic. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos; Argentina Fil: Solis, Patricia Cristina Lourdes. Universidad Nacional Arturo Jauretche. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos. Provincia de Buenos Aires. Ministerio de Salud. Hospital Alta Complejidad en Red El Cruce Dr. Néstor Carlos Kirchner Samic. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos; Argentina Fil: Kochen, Sara Silvia. Universidad Nacional Arturo Jauretche. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos. Provincia de Buenos Aires. Ministerio de Salud. Hospital Alta Complejidad en Red El Cruce Dr. Néstor Carlos Kirchner Samic. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos; Argentina Fil: D`alessio, Luciana. Universidad Nacional Arturo Jauretche. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos. Provincia de Buenos Aires. Ministerio de Salud. Hospital Alta Complejidad en Red El Cruce Dr. Néstor Carlos Kirchner Samic. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Unidad Ejecutora de Estudios en Neurociencias y Sistemas Complejos; Argentina

Published
2018

49. YouthMappers: a global network to empower students in mapping the world

Author

Rautenbach, Victoria, Minghini, Marco, Coetzee, Serena, and Solis, Patricia

Subjects
collaborative mapping, YouthMappers, OpenStreetMap, mapathons
Abstract

OpenStreetMap (OSM) is an openly-licensed geospatial database created and edited by millions of volunteers worldwide. This database is used in various humanitarian projects, such as mapping during disaster relief operations or malaria elimination campaigns. In some parts of the world, for example certain areas in Mozambique, no official cartographic data is available and hence OSM can play a crucial role. A mapathon (literally “map marathon”) is a collaborative effect that is an effective method of collecting map data in unmapped areas. Through the YouthMappers global initiative (http://www.youthmappers.org), students are actively engaging in OSM-based collaborative mapping efforts internationally. We will briefly discuss the process followed by three YouthMappers chapters; Politecnico di Milano (Italy), Texas Tech University (United States of America), and University of Pretoria (South Africa), and lessons learned. In Milano, students’ mapathons are organized monthly and they are focused either on field-mapping (e.g. to improve the OSM map of the university) or remote mapping on humanitarian tasks; learning sessions on OSM editing tools are also held periodically. In Texas, students organize mapathons several times per year, and they can take a dedicated service-learning course for credit where they work on teams with other students around the world to map the same areas and research the humanitarian or development issue affecting the region. In Pretoria, monthly mapathons are held and each mapathon focusses on a different area. Extra credits are offered to encourage participation. From our experiences, it became evident that even though OSM tools are user-friendly, students do need some training, and a short training video as part of the introduction presentation was developed. Additionally, understanding the purpose for a mapathon in an area, motivates and encourage active participation and ensures that quality data is captured. Internationally students participate and learn from other YouthMappers chapters through regular organized web conferences. In conclusion, incorporating mapathons into the curriculum encourages students to contribute needed data required for humanitarian projects. Simultaneously, students get practical experience in data capturing and awareness is raised of humanitarian challenges in other parts of the world.

Published
2017
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50. P1‐159: RARE VARIANTS IN PLCG2 , ABI3 , AND TREM2 GENES ARE ASSOCIATED WITH ALZHEIMER'S DISEASE IN AN ARGENTINIAN SAMPLE: IS IT A EUROPEAN HERITAGE?

Author

Dalmasso, Maria Carolina, primary, Brusco, Ignacio, additional, Olivar, Natividad, additional, Muchnik, Carolina, additional, Hanses, Claudia, additional, Milz, Esther, additional, Becker, Julian, additional, Prestia, Federico A., additional, Galeano, Pablo, additional, Carulla, Mariana E., additional, Azurmendi, Pablo J., additional, Liberczuk, Cynthia, additional, Fezza, Cristina, additional, Sampaño, Marcelo, additional, Fierens, Maria, additional, Jemar, Guillermo, additional, Sanchez-Avalos, Mariana S., additional, Martinez, Luis E., additional, Solis, Patricia, additional, Medel, Nancy, additional, Lisso, Julieta, additional, Sevillano, Zulma, additional, Behrens, Maria I., additional, Diaz-Grez, Fernando, additional, Castaño, Eduardo M., additional, Kairiyama, Claudia, additional, Politis, Gustavo D., additional, Kochen, Silvia, additional, Segura-Aguilar, Juan, additional, Scaro, Horacio, additional, Maier, Wolfgang, additional, Jessen, Frank, additional, Mangone, Carlos A., additional, Morelli, Laura, additional, and Ramirez, Alfredo, additional

Published
2018
Full Text
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