Search

Your search keyword '"Solimano, F."' showing total 24 results
Start Over Author "Solimano, F."
24 results on '"Solimano, F."'

14. A discrete model in population genetics: the fragile-X syndrome

Author

Pellerey, Franco, Rocchi, M. B. L., and Solimano, F.

Subjects
Computer Science::Information Theory
Abstract

A nonlinear discrete system, that describes how the fragile-X syndrome is transmitted through generations, is constructed. The problem of the existence of system's equilibria, depending on parameters, is considered, and some computer simulations are presented to study stability of these equilibria. Also, the results are compared with those already proposed in literature to describe the behaviour of the fragile-X syndrome., Statistica; Vol 61, No 1 (2001)

Published
2001

22. A mathematical model for drug administration by using the phagocytosis of red blood cells.

Author

Beretta E, Solimano F, and Takeuchi Y

Subjects
Erythrocyte Aging, Humans, Pharmacokinetics, Drug Therapy methods, Erythrocytes physiology, Macrophages, Models, Theoretical, Phagocytosis, Pharmaceutical Preparations administration & dosage
Abstract

A mathematical model for the delivery of drug directly to the macrophages by using the phagocytosis of senescent red blood cells is proposed. The model is based on the following assumption: At time t = 0 a preassigned red blood cell population n(0,a) = phi (a), a > 0, loaded by the drug, is injected in the blood circulation. Among the cells of that population only those with an age a > or = a (a = 120 days) will be phagocytosed by macrophages. Of course, the lifetime of the drug must be higher than a. Within the red blood cells it cannot be metabolized, neither can it diffuse through their membranes. The emphasis of the paper is on the mathematical properties and on the formulation of the control problem.

Published
1996
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results