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3 results on '"Sol S. Nety"'

1. Contributors

Author

R. Fanelwa Ajayi, Rana Al-Jaibachi, Simone Barry, Taurai Bere, Amanda Callaghan, Adroit T. Chakandinakira, Luke Chimuka, Joseph Clokey, Joyce Cristale, Ygor J.A.B. da Silva, Yuri J.A.B. da Silva, Tatenda Dalu, Jéssyca Ferreira de Medeiros, Eder de Vilhena Araújo, Simiso Dube, Juliana A. Galhardi, Sara G. Gorji, Leandro W. Hantao, Sayyed H. Hashemi, Darryl W. Hawker, Tatenda A. Kajau, Sarit L. Kaserzon, Massoud Kaykhaii, Temesgen G. Kebede, Sinegugu Khulu, Isaac Kudu, Ramesh B. Kumar, Karen Luko-Sulato, Lawrence M. Madikizela, Tinotenda Mangadze, Geaneth P. Mashile, Cassiana C. Montagner, Brenda Moodley, Babra Moyo, Anele Mpupa, Takalani Muluadzi, Nívea C.G. Munin, Herbert Musarurwa, Tongayi Mwedzi, Somandla Ncube, Nzumbululo Ndou, Sol S. Nety, Nokwanda Ngema, Mathew M. Nindi, Mulisa Nkuna, Azile Nqombolo, Philiswa N. Nomngongo, Sphamandla Nqunqa, Gershom M. Ntshani, Srinivas Oruganti, Vishalan Pillay, Tessia Rakgotho, Cornelius Rimayi, Edmond Sanganyado, Leandro M. Santos, Shirley K. Selahle, Saikat Sen, Nikita T. Tavengwa, Velaphi Thipe, Rahul K. Varma, Rory Verhagen, B.C. Vizioli, Lauren N.M. Yabuki, and Lewis D. Yardy

Published
2022
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3. Metabolite fingerprinting of ethyl acetate fraction of Kigelia africana fruit extracts: A comparison of chemical composition using GC–MS, GC-TOF-MS and UHPLC-TOF-MS/MS

Author

Gbenga S. Ogunleye, Oladoyin S. Fagbohun, Titus A.M. Msagati, Babatunde Olawoye, Sol S. Nety, and Oladapo F. Fagbohun

Subjects
chemistry.chemical_classification, Chromatography, Dried fruit, 010405 organic chemistry, Metabolite, Ethyl acetate, Glycoside, General Chemistry, 010402 general chemistry, Mass spectrometry, 01 natural sciences, 0104 chemical sciences, chemistry.chemical_compound, chemistry, Polyphenol, Gas chromatography–mass spectrometry, Time-of-flight mass spectrometry
Abstract

The present study profiled various chemical constituents from the ethyl acetate fraction of Kigelia africana fruit extract in a comparative manner using modern chromatographic methods coupled with mass spectrometric techniques. K. africana plant has a wide usage in folklore medicine for numerous ailments with the ethyl acetate fraction having high antifungal and anti-plasmodial activities. Dried fruits were extracted with ethanol and partitioned using ethyl acetate. The fraction was analyzed using GC–MS, GC-TOF-MS and UHPLC-TOF-MS/MS. Fifteen compounds consisting of 2-methoxy-4-vinylphenol, phenol-2,4-bis(1,1-dimethylethyl), - and 9,12,15-octadecatrienoic acid ethyl ester, (Z, Z, Z) – were obtained from GC–MS while 441 metabolites ranging from flavonoids, cardiac glycosides, and polyphenols were profiled from GC-TOF-MS whereas 235 metabolites were fingerprinted from UHPLC-TOF-MS/MS analysis by measuring m/z values and analyzing MS fragmentation pattern. From the identified phytochemicals through ultra-high-pressure liquid chromatography tandem mass spectrometer (UHPLC-TOF-MS/MS), 14 of them were confirmed and these include gemfibrozil, trimetazidine, and leucomalachite green.

Published
2021
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