20 results on '"Solís-Labastida, Karina"'
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2. Global expression profiling of CD10 + /CD19 + pre-B lymphoblasts from Hispanic B-ALL patients correlates with comparative TARGET database analysis
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Castañeda-Partida, Laura, Ocadiz-Delgado, Rodolfo, Sánchez-López, José Manuel, García-Villa, Enrique, Peñaloza-González, José Gabriel, Velázquez-Aviña, Martha Margarita, Torres-Nava, José Refugio, Martín-Trejo, Jorge Alfonso, Solís-Labastida, Karina, Guerra-Castillo, Francisco Xavier, Bekker-Méndez, Vilma Carolina, Rosales-García, Víctor Hugo, Romero-Rodríguez, Dámaris, Mojica-Espinoza, Raúl, Mendez-Tenorio, Alfonso, Ramírez-Calzada, Crystel A., Álvarez-Ríos, Elízabeth, Mejía-Aranguré, Juan Manuel, and Gariglio, Patricio
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- 2022
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3. Changes in RANKL, OPG, and 25(OH)D Levels in Children with Leukemia from Diagnosis to Remission.
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Atilano-Miguel, Salvador, Barbosa-Cortés, Lourdes, Ortiz-Muñiz, Rocío, Maldonado-Hernández, Jorge, Martin-Trejo, Jorge A., Rodríguez-Cruz, Maricela, Balcázar-Hernández, Lourdes, Solís-Labastida, Karina A., Bautista-Martínez, Benito A., Juárez-Moya, Azalia, Hernández-Piñón, Zayra, Galindo-Rodríguez, Raeline A., Chávez-Anaya, Adriana, Valdez-Avilez, Rosa E., Domínguez-Salgado, Juan M., Villa-Morales, Judith, and Rodríguez-Palacios, María E.
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LYMPHOBLASTIC leukemia diagnosis ,BONE resorption ,VITAMIN D deficiency ,RESEARCH funding ,CANCER relapse ,SCIENTIFIC observation ,BONE growth ,BLOOD collection ,DISEASE remission ,CELLULAR signal transduction ,TUMOR markers ,CHILDREN'S hospitals ,DESCRIPTIVE statistics ,CANCER chemotherapy ,LONGITUDINAL method ,REMISSION induction ,LYMPHOBLASTIC leukemia ,VITAMIN D ,MEMBRANE proteins ,CELL receptors ,BONE remodeling ,BLOOD - Abstract
Simple Summary: Advances in the treatment of acute lymphoblastic leukemia (ALL) have led to a marked improvement in the survival rate of patients. Nevertheless, these patients may develop adverse effects during and after treatment, such as bone abnormalities and vitamin D deficiency. Bone remodeling allows for bone volume and structure to be maintained, which is controlled by the receptor activator of the nuclear factor-kB (RANK)/RANK ligand (RANKL)/osteoprotegerin (OPG) system-determining pathway in the balance between bone formation and resorption. Some reports have explored the role of corticosteroids in modulating the RANKL and OPG levels and RANKL/OPG ratio in pediatric patients. Nevertheless, studies evaluating the role of RANKL and OPG in the bone health of pediatric ALL patients during treatment are limited. During remission, we observed an increase in the RANKL/OPG ratio, increased RANKL levels, and decreased OPG levels in ALL patients. These changes may predispose such patients to the development of bone health disorders in their adult lives. Background: The receptor activator of the nuclear factor-kB (RANK)/RANK ligand (RANKL)/osteoprotegerin (OPG) pathway is a determining pathway in the balance between bone formation and resorption, and disruptions in this complex can affect bone metabolism. Methods: This study analyzes the changes in RANKL, OPG, and 25(OH)D levels; the RANKL/OPG ratio; and other bone turnover markers (BTMs) from diagnosis to complete remission in children with acute lymphoblastic leukemia (ALL). This is a prospective observational cohort study, carried out at the Instituto Mexicano del Seguro Social, Mexico City, including 33 patients (4–17 years) with newly diagnosed B-cell ALL. The patients were treated with the HP09 chemotherapy protocol. Children who had previously been treated with corticosteroids were excluded. A peripheral blood sample at diagnosis and remission was collected to determine the 25(OH)D and BTM concentrations. Results: Increased RANKL (p = 0.001) and osteocalcin (p < 0.001) levels and RANKL/OPG ratio (<0.001) and a decreased OPG level (p = 0.005) were observed at remission, predominantly in the high-risk (HR) relapse and vitamin D deficiency groups. A negative association between RANKL and OPG (r = −0.454, p = 0.008) was observed. Conclusions: we suggest that the RANKL/OPG ratio could serve as a bone remodeling marker in ALL patients. [ABSTRACT FROM AUTHOR]
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- 2024
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4. Rivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial
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Molinari, Angelo C., Nowak Göttl, Ulrike, Chain, Juan, Robertson, Jeremy, Thom, Katharina, Streif, Werner, Schwarz, Rudolf, Schmitt, Klaus, Grangl, Gernot, Van Damme, An, Maes, Philip, Labarque, Veerle, Petrilli, Antonio, Loggeto, Sandra, Azeka, Estela, Brandao, Leonardo, Le, Doan, Sabapathy, Christine, Giordano, Paola, Wu, Runhui, Ding, Jie, Huang, Wenyan, Mao, Jianhua, Lähteenmäki, Päivi, Amedro, Pascal, Decramer, Stephane, Bernig, Toralf, Chada, Martin, Chan, Godfrey, Kally, Krisztian, Nolan, Beatrice, Revel-Vilk, Shoshana, Tamary, Hannah, Levin, Carina, Tormene, Daniela, Abbattista, Maria, Artoni, Andrea, Ikeyama, Takanari, Inuzuka, Ryo, Yasukochi, Satoshi, Morales Soto, Michelle, Solis Labastida, Karina A, Suijker, Monique H, Bartels, Marike, Tamminga, Rienk Y, Van Ommen, C Heleen, Te Loo, D. Maroeska, Anjos, Rui, Zubarovskaya, Lyudmila, Popova, Natalia, Samochatova, Elena, Belogurova, Margarita, Svirin, Pavel, Shutova, Tatiana, Lebedev, Vladimir, Barbarash, Olga, Koh, Pei L, Mei, Joyce C, Podracka, Ludmila, Berrueco, Ruben, Fernandez, Maria F, Frisk, Tony, Grunt, Sebastian, Rischewski, Johannes, Albisetti-Pedroni, Manuela, Antmen, Ali, Tokgoz, Huseyin, Karakas, Zeynep, Chalmers, Elizabeth, Motwani, Jayashree, Williams, Michael, Grainger, John, Payne, Jeanette, Richards, Mike, Baird, Susan, Bhatnagar, Neha, Aramburo, Angela, Crary, Shelley, Wynn, Tung, Carpenter, Shannon, Hege, Kerry, Ahuja, Sanjay, Goldenberg, Neil, Woods, Gary, Godder, Kamar, Scott-Emuakpor, Ajovi, Roach, Gavin, Raffini, Leslie, Shah, Nirmish, Shah, Sanjay, Thornburg, Courtney, Zia, Ayesha, Berkow, Roger, Male, Christoph, Lensing, Anthonie W A, Palumbo, Joseph S, Kumar, Riten, Nurmeev, Ildar, Bonnet, Damien, Connor, Philip, Hooimeijer, Hélène L, Torres, Marcela, Chan, Anthony K C, Kenet, Gili, Holzhauer, Susanne, Santamaría, Amparo, Simioni, Paolo, Bhat, Rukhmi V, Yee, Donald L, Lvova, Olga, Beyer-Westendorf, Jan, Biss, Tina T, Martinelli, Ida, Saracco, Paola, Peters, Marjolein, Kállay, Krisztián, Gauger, Cynthia A, Massicotte, M Patricia, Young, Guy, Pap, Akos F, Majumder, Madhurima, Smith, William T, Heubach, Jürgen F, Berkowitz, Scott D, Thelen, Kirstin, Kubitza, Dagmar, Crowther, Mark, Prins, Martin H, and Monagle, Paul
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- 2020
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5. Evidence of spatial clustering of childhood acute lymphoblastic leukemia cases in Greater Mexico City: report from the Mexican Inter-Institutional Group for the identification of the causes of childhood leukemia
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Duarte-Rodríguez, David Aldebarán, primary, Flores-Lujano, Janet, additional, McNally, Richard J. Q., additional, Pérez-Saldivar, María Luisa, additional, Jiménez-Hernández, Elva, additional, Martín-Trejo, Jorge Alfonso, additional, Espinoza-Hernández, Laura Eugenia, additional, Medina-Sanson, Aurora, additional, Paredes-Aguilera, Rogelio, additional, Merino-Pasaye, Laura Elizabeth, additional, Velázquez-Aviña, Martha Margarita, additional, Torres-Nava, José Refugio, additional, Espinosa-Elizondo, Rosa Martha, additional, Amador-Sánchez, Raquel, additional, Dosta-Herrera, Juan José, additional, Mondragón-García, Javier Anastacio, additional, González-Ulibarri, Juana Esther, additional, Martínez-Silva, Sofía Irene, additional, Espinoza-Anrubio, Gilberto, additional, Paz-Bribiesca, María Minerva, additional, Salcedo-Lozada, Perla, additional, Landa-García, Rodolfo Ángel, additional, Ramírez-Colorado, Rosario, additional, Hernández-Mora, Luis, additional, Santamaría-Ascencio, Marlene, additional, López-Loyola, Anselmo, additional, Godoy-Esquivel, Arturo Hermilo, additional, García-López, Luis Ramiro, additional, Anguiano-Ávalos, Alison Ireri, additional, Mora-Rico, Karina, additional, Castañeda-Echevarría, Alejandro, additional, Rodríguez-Jiménez, Roberto, additional, Cibrian-Cruz, José Alberto, additional, Solís-Labastida, Karina Anastacia, additional, Cárdenas-Cardos, Rocío, additional, López-Santiago, Norma, additional, Flores-Villegas, Luz Victoria, additional, Peñaloza-González, José Gabriel, additional, González-Ávila, Ana Itamar, additional, Sánchez-Ruiz, Martin, additional, Rivera-Luna, Roberto, additional, Rodríguez-Villalobos, Luis Rodolfo, additional, Hernández-Pérez, Francisco, additional, Olvera-Durán, Jaime Ángel, additional, García-Cortés, Luis Rey, additional, Mata-Rocha, Minerva, additional, Sepúlveda-Robles, Omar Alejandro, additional, Bekker-Méndez, Vilma Carolina, additional, Jiménez-Morales, Silvia, additional, Meléndez-Zajgla, Jorge, additional, Rosas-Vargas, Haydée, additional, Vega, Elizabeth, additional, Núñez-Enríquez, Juan Carlos, additional, and Mejía-Aranguré, Juan Manuel, additional
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- 2024
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6. Association between genetic variants of membrane transporters and the risk of high-grade hematologic adverse events in a cohort of Mexican children with B-cell acute lymphoblastic leukemia
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Escalante-Bautista, Deyanira, primary, Cerecedo, Doris, additional, Jiménez-Hernández, Elva, additional, González-Torres, Carolina, additional, Gaytán-Cervantes, Javier, additional, Núñez-Enríquez, Juan Carlos, additional, Sepúlveda-Robles, Omar Alejandro, additional, De Ita, Marlon, additional, Jiménez-Morales, Silvia, additional, Sánchez-López, José Manuel, additional, Mata-Rocha, Minerva, additional, Torres-Nava, José Refugio, additional, Martín-Trejo, Jorge Alfonso, additional, Flores-Villegas, Luz Victoria, additional, Gutiérrez-Rivera, María de Lourdes, additional, Merino-Pasaye, Laura Elizabeth, additional, Solís-Labastida, Karina Anastacia, additional, Miranda-Madrazo, María Raquel, additional, Hernández-Echáurregui, Gabriela Alicia, additional, Orozco-Ruíz, Darío, additional, Flores-Lujano, Janet, additional, Pérez-Saldívar, María Luisa, additional, Mejía-Aranguré, Juan Manuel, additional, and Rosas-Vargas, Haydeé, additional
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- 2024
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7. Maternal dietary patterns and acute leukemia in infants: results from a case control study in Mexico
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Muñoz-Aguirre, Paloma, primary, Denova-Gutiérrez, Edgar, additional, Pérez-Saldivar, María Luisa, additional, Espinoza-Hernández, Laura E., additional, Dorantes-Acosta, Elisa M., additional, Torres-Nava, José R., additional, Solís-Labastida, Karina A., additional, Paredes-Aguilera, Rogelio, additional, Velázquez-Aviña, Martha M., additional, Espinosa-Elizondo, R. Martha, additional, Miranda-Madrazo, M. Raquel, additional, González-Ávila, Ana Itamar, additional, Rodríguez-Villalobos, Luis Rodolfo, additional, Dosta-Herrera, Juan José, additional, Mondragón-García, Javier A., additional, Castañeda-Echevarría, Alejandro, additional, López-Caballero, M. Guadalupe, additional, Martínez-Silva, Sofía I., additional, Rivera-González, Juan, additional, Hernández-Pineda, Norma Angélica, additional, Flores-Botello, Jesús, additional, Pérez-Gómez, Jessica Arleet, additional, Rodríguez-Vázquez, María Adriana, additional, Torres-Valle, Delfino, additional, Olvera-Durán, Jaime Ángel, additional, Martínez-Ríos, Annel, additional, García-Cortés, Luis R., additional, Almeida-Hernández, Carolina, additional, Flores-Lujano, Janet, additional, Núñez-Enriquez, Juan Carlos, additional, Mata-Rocha, Minerva, additional, Rosas-Vargas, Haydeé, additional, Duarte-Rodríguez, David Aldebarán, additional, Jiménez-Morales, Silvia, additional, Mejía-Aranguré, Juan Manuel, additional, and López-Carrillo, Lizbeth, additional
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- 2023
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8. A protective maternal nutrient concomitant intake associated with acute leukemia might be modified by sex, in children under 2 years
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Mérida-Ortega, Ángel, primary, Pérez-Saldivar, María Luisa, additional, Espinoza-Hernández, Laura E., additional, Dorantes-Acosta, Elisa M., additional, Torres-Nava, José Refugio, additional, Solís-Labastida, Karina A., additional, Paredes-Aguilera, Rogelio, additional, Velázquez-Aviña, Martha M., additional, Espinosa-Elizondo, Rosa Martha, additional, Miranda-Madrazo, M. Raquel, additional, González-Ávila, Ana Itamar, additional, Rodríguez-Villalobos, Luis Rodolfo, additional, Dosta-Herrera, Juan José, additional, Mondragón-García, Javier A., additional, Castañeda-Echevarría, Alejandro, additional, López-Caballero, M. Guadalupe, additional, Martínez-Silva, Sofía I., additional, Rivera-González, Juan, additional, Hernández-Pineda, Norma Angélica, additional, Flores-Botello, Jesús, additional, Pérez-Gómez, Jessica Arleet, additional, Rodríguez-Vázquez, María Adriana, additional, Torres-Valle, Delfino, additional, Olvera-Durán, Jaime Ángel, additional, Martínez-Ríos, Annel, additional, García‐Cortés, Luis R., additional, Almeida-Hernández, Carolina, additional, Flores-Lujano, Janet, additional, Núñez-Enríquez, Juan Carlos, additional, Mata-Rocha, Minerva, additional, Rosas-Vargas, Haydeé, additional, Duarte-Rodríguez, David Aldebarán, additional, Jiménez-Morales, Silvia, additional, Mejía-Arangure, Juan Manuel, additional, and López-Carrillo, Lizbeth, additional
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- 2023
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9. Analytical study of RUNX1-RUNXT1, PML-RARA, CBFB-MYH11, BCR-ABL1p210, and KMT2-MLLT3 in Mexican children with acute myeloid leukemia: A multicenter study of the Mexican interinstitutional group for the identification of the causes of childhood leukemia (MIGICCL)
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Sepúlveda-Robles, Omar, primary, Jiménez-Hernández, Elva, additional, Domínguez-Catzín, Victoria, additional, Gómez-Flores, Eber, additional, Martín-Trejo, Jorge Alfonso, additional, Flores-Lujano, Janet, additional, Torres-Nava, José Refugio, additional, Núñez-Enríquez, Juan Carlos, additional, De Ita, Marlon, additional, Medina-Sanson, Aurora, additional, Mata-Rocha, Minerva, additional, Morales-Castillo, Blanca Angelica, additional, Bravata-Alcántara, Juan Carlos, additional, Nájera-Cortés, Alan Steve, additional, Sánchez-Escobar, Norberto, additional, Peñaloza-Gonzalez, José Gabriel, additional, Espinosa-Elizondo, Rosa Martha, additional, Flores-Villegas, Luz Victoria, additional, Amador-Sanchez, Raquel, additional, Orozco-Ruiz, Darío, additional, Pérez-Saldívar, Maria Luisa, additional, Velázquez-Aviña, Martha Margarita, additional, Merino-Pasaye, Laura Elizabeth, additional, Solís-Labastida, Karina Anastacia, additional, González-Ávila, Ana Itamar, additional, Santillán-Juárez, Jessica Denisse, additional, Bekker-Méndez, Vilma Carolina, additional, Jiménez-Morales, Silvia, additional, Rangel-López, Angélica, additional, Rosas-Vargas, Haydeé, additional, and Mejía-Aranguré, Juan Manuel, additional
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- 2022
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10. NK cells with decreased expression of multiple activating receptors is a dominant phenotype in pediatric patients with acute lymphoblastic leukemia
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Valenzuela-Vázquez, Lucero, primary, Nuñez-Enriquez, Juan Carlos, additional, Sánchez-Herrera, Jacqueline, additional, Medina-Sanson, Aurora, additional, Pérez-Saldivar, María Luisa, additional, Jiménez-Hernández, Elva, additional, Martiín-Trejo, Jorge Alfonso, additional, Del Campo-Martínez, María de Los Ángeles, additional, Flores-Lujano, Janet, additional, Amador-Sánchez, Raquel, additional, Mora-Ríos, Félix Gustavo, additional, Peñaloza-González, José Gabriel, additional, Duarte-Rodríguez, David Aldebarán, additional, Torres-Nava, José Refugio, additional, Espinosa-Elizondo, Rosa Martha, additional, Cortés-Herrera, Beatriz, additional, Flores-Villegas, Luz Victoria, additional, Merino-Pasaye, Laura Elizabeth, additional, Almeida-Hernández, Carolina, additional, Ramírez-Colorado, Rosario, additional, Solís-Labastida, Karina Anastacia, additional, Medrano-López, Francisco, additional, Pérez-Gómez, Jessica Arleet, additional, Velázquez-Aviña, Martha Margarita, additional, Martínez-Ríos, Annel, additional, Aguilar-De los Santos, Antonio, additional, Santillán-Juárez, Jessica Denisse, additional, Gurrola-Silva, Alma, additional, García-Velázquez, Alejandra Jimena, additional, Mata-Rocha, Minerva, additional, Hernández-Echáurregui, Gabriela Alicia, additional, Sepúlveda-Robles, Omar Alejandro, additional, Rosas-Vargas, Haydeé, additional, Mancilla-Herrera, Ismael, additional, Jimenez-Morales, Silvia, additional, Hidalgo-Miranda, Alfredo, additional, Martinez-Duncker, Ivan, additional, Waight, Jeremy D., additional, Hance, Kenneth W., additional, Madauss, Kevin P., additional, Mejía-Aranguré, Juan Manuel, additional, and Cruz-Munoz, Mario Ernesto, additional
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- 2022
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11. Persistently high incidence rates of childhood acute leukemias from 2010 to 2017 in Mexico City: A population study from the MIGICCL
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Flores-Lujano, Janet, primary, Duarte-Rodríguez, David Aldebarán, additional, Jiménez-Hernández, Elva, additional, Martín-Trejo, Jorge Alfonso, additional, Allende-López, Aldo, additional, Peñaloza-González, José Gabriel, additional, Pérez-Saldivar, María Luisa, additional, Medina-Sanson, Aurora, additional, Torres-Nava, José Refugio, additional, Solís-Labastida, Karina Anastacia, additional, Flores-Villegas, Luz Victoria, additional, Espinosa-Elizondo, Rosa Martha, additional, Amador-Sánchez, Raquel, additional, Velázquez-Aviña, Martha Margarita, additional, Merino-Pasaye, Laura Elizabeth, additional, Núñez-Villegas, Nora Nancy, additional, González-Ávila, Ana Itamar, additional, del Campo-Martínez, María de los Ángeles, additional, Alvarado-Ibarra, Martha, additional, Bekker-Méndez, Vilma Carolina, additional, Cárdenas-Cardos, Rocío, additional, Jiménez-Morales, Silvia, additional, Rivera-Luna, Roberto, additional, Rosas-Vargas, Haydee, additional, López-Santiago, Norma C., additional, Rangel-López, Angélica, additional, Hidalgo-Miranda, Alfredo, additional, Vega, Elizabeth, additional, Mata-Rocha, Minerva, additional, Sepúlveda-Robles, Omar Alejandro, additional, Arellano-Galindo, José, additional, Núñez-Enríquez, Juan Carlos, additional, and Mejía-Aranguré, Juan Manuel, additional
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- 2022
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12. Development and Validation of a One-Step RT-qPCR Assay for Identifying Common Fusion Gene Transcripts Associated with the Prognosis of Mexican Children with B-Lineage Acute Lymphoblastic Leukemia
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Mejía-Aranguré, Juan Manuel, primary, Mata-Rocha, Minerva, additional, Rangel-López, Angelica, additional, Núñez-Enríquez, Juan Carlos, additional, Jiménez-Hernández, Elva, additional, Morales-Castillo, Blanca Angélica, additional, Sánchez-Escobar, Norberto, additional, Sepúlveda-Robles, Omar Alejandro, additional, Bravata-Alcántara, Juan Carlos, additional, Nájera-Cortés, Alan Steve, additional, Pérez-Saldivar, María Luisa, additional, Flores-Lujano, Janet, additional, Duarte-Rodríguez, David Aldebarán, additional, de Anda, Norma Angélica Oviedo, additional, Verson, Carmen Alaez, additional, Martín-Trejo, Jorge Alfonso, additional, Campo-Martínez, María de Los Ángeles Del, additional, Muñoz-Medina, José Esteban, additional, González-Bonilla, César Raúl, additional, Cueto, Maria de los Angeles Hernandez, additional, Medina-Sansón, Aurora, additional, Amador-Sánchez, Raquel, additional, Peñaloza-González, José Gabriel, additional, Torres-Nava, José Refugio, additional, Espinosa-Elizondo, Rosa Martha, additional, Cortés-Herrera, Beatriz, additional, Flores-Villegas, Luz Victoria, additional, Merino-Pasaye, Laura Elizabeth, additional, Solís-Labastida, Karina Anastacia, additional, Velázquez-Aviña, Martha Margarita, additional, Santillán-Juárez, Jessica Denisse, additional, Gurrola-Silva, Alma, additional, García-Velázquez, Alejandra Jimena, additional, Echáurregui, Gabriela Alicia Hernández, additional, and Rosas-Vargas, Haydeé, additional
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- 2021
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13. Copy Number Alterations are Associated with the Risk of Very Early Relapse in Pediatric B-lineage Acute Lymphoblastic Leukemia: A Nested Case-control MIGICCL Study
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Rosales-Rodríguez, Beatriz, primary, Núñez-Enríquez, Juan Carlos, additional, Velázquez-Wong, Ana Claudia, additional, González-Torres, Carolina, additional, Gaytán-Cervantes, Javier, additional, Jiménez-Hernández, Elva, additional, Martín-Trejo, Jorge Alfonso, additional, Campo-Martínez, María de los Ángeles del, additional, Medina-Sanson, Aurora, additional, Flores-Lujano, Janet, additional, Flores-Villegas, Luz Victoria, additional, Peñaloza-González, José Gabriel, additional, Torres-Nava, José Refugio, additional, Espinosa-Elizondo, Rosa Martha, additional, Amador-Sánchez, Raquel, additional, Miranda-Madrazo, María Raquel, additional, Santillán-Juárez, Jessica Denise, additional, Pérez-Saldívar, María Luisa, additional, Gurrola-Silva, Alma, additional, Orozco-Ruiz, Darío, additional, Solís-Labastida, Karina Anastacia, additional, Velázquez-Aviña, Martha Margarita, additional, Duarte-Rodríguez, David Aldebarán, additional, Mata-Rocha, Minerva, additional, Sepúlveda-Robles, Omar Alejandro, additional, Ortiz-Maganda, Mónica, additional, Bekker-Méndez, Vilma Carolina, additional, Jiménez-Morales, Silvia, additional, Mejía-Aranguré, Juan Manuel, additional, and Rosas-Vargas, Haydeé, additional
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- 2021
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14. Transcriptome Analysis Identifies LINC00152 as a Biomarker of Early Relapse and Mortality in Acute Lymphoblastic Leukemia
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Bárcenas-López, Diego Alberto, primary, Núñez-Enríquez, Juan Carlos, additional, Hidalgo-Miranda, Alfredo, additional, Beltrán-Anaya, Fredy Omar, additional, May-Hau, Didier Ismael, additional, Jiménez-Hernández, Elva, additional, Bekker-Méndez, Vilma Carolina, additional, Flores-Lujano, Janet, additional, Medina-Sansón, Aurora, additional, Tamez-Gómez, Edna Liliana, additional, López-García, Víctor Hugo, additional, Lara-Ramos, José Ramón, additional, Núñez-Villegas, Nora Nancy, additional, Peñaloza-González, José Gabriel, additional, Flores-Villegas, Luz Victoria, additional, Amador-Sánchez, Raquel, additional, Espinosa-Elizondo, Rosa Martha, additional, Martín-Trejo, Jorge Alfonso, additional, Velázquez-Aviña, Martha Margarita, additional, Merino-Pasaye, Laura Elizabeth, additional, Pérez-Saldívar, María Luisa, additional, Duarte-Rodríguez, David Aldebarán, additional, Torres-Nava, José Refugio, additional, Cortés-Herrera, Beatriz, additional, Solís-Labastida, Karina Anastacia, additional, González-Ávila, Ana Itamar, additional, Santillán-Juárez, Jessica Denisse, additional, García-Velázquez, Alejandra Jimena, additional, Rosas-Vargas, Haydee, additional, Mata-Rocha, Minerva, additional, Sepúlveda-Robles, Omar Alejandro, additional, Mejía-Aranguré, Juan Manuel, additional, and Jiménez-Morales, Silvia, additional
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- 2020
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15. Identification and Characterization of Novel Fusion Genes with Potential Clinical Applications in Mexican Children with Acute Lymphoblastic Leukemia
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Mata-Rocha, Minerva, primary, Rangel-López, Angelica, additional, Jiménez-Hernández, Elva, additional, Morales-Castillo, Blanca Angélica, additional, González-Torres, Carolina, additional, Gaytan-Cervantes, Javier, additional, Álvarez-Olmos, Enrique, additional, Núñez-Enríquez, Juan Carlos, additional, Fajardo-Gutiérrez, Arturo, additional, Martín-Trejo, Jorge Alfonso, additional, Solís-Labastida, Karina Anastacia, additional, Medina-Sansón, Aurora, additional, Flores-Lujano, Janet, additional, Sepúlveda-Robles, Omar Alejandro, additional, Peñaloza-González, José Gabriel, additional, Espinoza-Hernández, Laura Eugenia, additional, Núñez-Villegas, Nora Nancy, additional, Espinosa-Elizondo, Rosa Martha, additional, Cortés-Herrera, Beatriz, additional, Torres-Nava, José Refugio, additional, Flores-Villegas, Luz Victoria, additional, Merino-Pasaye, Laura Elizabeth, additional, Bekker-Méndez, Vilma Carolina, additional, Velázquez-Aviña, Martha Margarita, additional, Pérez-Saldívar, María Luisa, additional, Bautista-Martínez, Benito Alejandro, additional, Amador-Sánchez, Raquel, additional, González-Avila, Ana Itamar, additional, Jiménez-Morales, Silvia, additional, Duarte-Rodríguez, David Aldebarán, additional, Santillán-Juárez, Jessica Denisse, additional, García-Velázquez, Alejandra Jimena, additional, Rosas-Vargas, Haydeé, additional, and Mejía-Aranguré, Juan Manuel, additional
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- 2019
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16. A greater birthweight increases the risk of acute leukemias in Mexican children-experience from the Mexican Interinstitutional Group for the Identification of the Causes of Childhood Leukemia (MIGICCL)
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Jiménez-Hernández, Elva, primary, Fajardo-Gutiérrez, Arturo, additional, Núñez-Enriquez, Juan Carlos, additional, Martín-Trejo, Jorge Alfonso, additional, Espinoza-Hernández, Laura Eugenia, additional, Flores-Lujano, Janet, additional, Arellano-Galindo, José, additional, Medina-Sanson, Aurora, additional, Paredes-Aguilera, Rogelio, additional, Merino-Pasaye, Laura Elizabeth, additional, Velázquez-Aviña, Martha Margarita, additional, Torres-Nava, José Refugio, additional, Espinosa-Elizondo, Rosa Martha, additional, Amador-Sánchez, Raquel, additional, Dosta-Herrera, Juan José, additional, Mondragón-García, Javier Anastacio, additional, Valdés-Guzmán, Heriberto, additional, Mejía-Pérez, Laura, additional, Espinoza-Anrubio, Gilberto, additional, Paz-Bribiesca, María Minerva, additional, Salcedo-Lozada, Perla, additional, Landa-García, Rodolfo Ángel, additional, Ramírez-Colorado, Rosario, additional, Hernández-Mora, Luis, additional, Pérez-Saldivar, María Luisa, additional, Santamaría-Ascencio, Marlene, additional, López-Loyola, Anselmo, additional, Godoy-Esquivel, Arturo Hermilo, additional, García-López, Luis Ramiro, additional, Anguiano-Ávalos, Alison Ireri, additional, Mora-Rico, Karina, additional, Castañeda-Echevarría, Alejandro, additional, Rodríguez-Jiménez, Roberto, additional, Cibrian-Cruz, José Alberto, additional, Solís-Labastida, Karina Anastacia, additional, Cárdenas-Cardos, Rocío, additional, Martínez-Avalos, Armando, additional, Flores-Villegas, Luz Victoria, additional, Peñaloza-González, José Gabriel, additional, González-Ávila, Ana Itamar, additional, Altamirano-García, Martha Beatriz, additional, López-Santiago, Norma, additional, Sánchez-Ruiz, Martin, additional, Rivera-Luna, Roberto, additional, Rodríguez-Villalobos, Luis Rodolfo, additional, Hernández-Pérez, Francisco, additional, Olvera-Durán, Jaime Ángel, additional, García-Cortés, Luis Rey, additional, Mata-Rocha, Minerva, additional, Sepúlveda-Robles, Omar Alejandro, additional, González-Bonilla, Cesar Raúl, additional, Bekker-Méndez, Vilma Carolina, additional, Jiménez-Morales, Silvia, additional, Rosas-Vargas, Haydee, additional, and Mejía-Aranguré, Juan Manuel, additional
- Published
- 2018
- Full Text
- View/download PDF
17. Survival of Mexican Children with Acute Myeloid Leukaemia Who Received Early Intensification Chemotherapy and an Autologous Transplant
- Author
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Jiménez-Hernández, Elva, primary, Dueñas-González, María Teresa, additional, Arellano-Galindo, José, additional, Medrano-Ortíz-De-Zárate, María Elena, additional, Bekker-Méndez, Vilma Carolina, additional, Berges-García, Adolfina, additional, Solís-Labastida, Karina, additional, Sánchez-Jara, Berenice, additional, Tiznado-García, Héctor Manuel, additional, Jaimes-Reyes, Ethel Zulie, additional, García-Jiménez, Xochiketzalli, additional, Espinoza-Hernández, Laura, additional, Núñez-Villegas, Nora Nancy, additional, Franco-Ornelas, Sergio, additional, Pérez-Casillas, Ruy Xavier, additional, Martínez Villegas, Octavio, additional, Palomares, Teresa Marin, additional, and Mejía-Aranguré, Juan Manuel, additional
- Published
- 2015
- Full Text
- View/download PDF
18. Enfermedad de Gaucher:.
- Author
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Franco-Ornelas, Sergio, González-Vite, Mario, Núñez-Villegas, Nancy, Solís-Labastida, Karina, and Brito-Trejo, Jorge Mena
- Subjects
GAUCHER'S disease ,GLUCOSIDASES ,GENETIC disorders ,PEDIATRICS ,INDIVIDUALIZED medicine ,LYSOSOMES - Abstract
Copyright of Revista Medica del IMSS is the property of Direccion de Prestaciones Medicas - IMSS and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2012
19. Analytical study of RUNX1-RUNXT1 , PML-RARA , CBFB-MYH11 , BCR-ABL1 p210 , and KMT2-MLLT3 in Mexican children with acute myeloid leukemia: A multicenter study of the Mexican interinstitutional group for the identification of the causes of childhood leukemia (MIGICCL).
- Author
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Sepúlveda-Robles O, Jiménez-Hernández E, Domínguez-Catzín V, Gómez-Flores E, Martín-Trejo JA, Flores-Lujano J, Torres-Nava JR, Núñez-Enríquez JC, De Ita M, Medina-Sanson A, Mata-Rocha M, Morales-Castillo BA, Bravata-Alcántara JC, Nájera-Cortés AS, Sánchez-Escobar N, Peñaloza-Gonzalez JG, Espinosa-Elizondo RM, Flores-Villegas LV, Amador-Sanchez R, Orozco-Ruiz D, Pérez-Saldívar ML, Velázquez-Aviña MM, Merino-Pasaye LE, Solís-Labastida KA, González-Ávila AI, Santillán-Juárez JD, Bekker-Méndez VC, Jiménez-Morales S, Rangel-López A, Rosas-Vargas H, and Mejía-Aranguré JM
- Abstract
Background: The distribution of RUNX1-RUNXT1 , PML-RARA , CBFB-MYH11 , BCR-ABL1
p210 , and KMT2A-MLLT3 in the pediatric population with acute myeloid leukemia (AML) in many countries of Latin America is largely unknown. Therefore, we aimed to investigate the frequency of these fusion genes in children with de novo AML from Mexico City, which has one of the highest incidence rates of acute leukemia in the world. Additionally, we explored their impact in mortality during the first year of treatment., Methods: We retrospectively analyzed the presence of RUNX1-RUNXT1 , PML-RARA , CBFB-MYH11 , BCR-ABL1p210 , and KMT2A-MLLT3 by RT-PCR among 77 patients (<18 years) diagnosed with de novo AML between 2019 and 2021 in nine Mexico City hospitals., Results: The overall frequency of the fusion genes was 50.7%; RUNX1-RUNXT1 (22.1%) and PML-RARA (20.8%) were the most prevalent, followed by CBFB-MYH11 (5.2%) and BCR-ABL1p210 (2.4%). KMT2A-MLLT3 was not detected. Patients with PML-RARA showed the lowest survival with high early mortality events. However, more studies are required to evaluate the impact of analyzed fusion genes on the overall survival of the Mexican child population with AML., Conclusion: The pediatric population of Mexico City with AML had frequencies of AML1-ETO , PML-RARA , CBFB-MYH11 , and BCR-ABL1p210 similar to those of other populations around the world. Patients with BCR-ABL1p210 and CBFB-MYH11 were few or did not die, while those with MLL-AF9 was not detected. Although patients with PML-RARA had a low survival and a high early mortality rate, further studies are needed to determine the long-term impacts of these fusion genes on this Latino population., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (© 2022 Sepúlveda-Robles, Jiménez-Hernández, Domínguez-Catzín, Gómez-Flores, Martín-Trejo, Flores-Lujano, Torres-Nava, Núñez-Enríquez, De Ita, Medina Sanson, Mata-Rocha, Morales-Castillo, Bravata-Alcántara, Nájera-Cortés, Sánchez-Escobar, Peñaloza-Gonzalez, Espinosa-Elizondo, Flores-Villegas, Amador-Sánchez, Orozco-Ruiz, Pérez-Saldívar, Velázquez-Aviña, Merino-Pasaye, Solís-Labastida, González-Ávila, Santillán-Juárez, Bekker-Méndez, Jiménez-Morales, Rangel-López, Rosas-Vargas and Mejía-Aranguré.)- Published
- 2022
- Full Text
- View/download PDF
20. [Gaucher's disease: clinical picture in 11 children].
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Franco-Ornelas S, González-Vite M, Núñez-Villegas N, Solís-Labastida K, and Brito-Trejo JM
- Subjects
- Adolescent, Child, Child, Preschool, Female, Gaucher Disease therapy, Humans, Infant, Male, Retrospective Studies, Gaucher Disease diagnosis
- Abstract
Background: Gaucher's disease, the most prevalent lysosome storage disorder, presents an autosomal recessive mode of inheritance with a deficiency of the acid b-glucosidase enzyme. Our objective was to describe the clinical features, symptoms, evolution and treatment of Gaucher's disease in Mexican pediatric patients., Methods: the medical files of every patient diagnosed with Gaucher's treated during the last 11 years at the Pediatrics Department at General Hospital "Dr. Gaudencio González Garza" were reviewed. Demographic and clinical data were registered., Results: eleven patients were diagnosed with Gaucher's Disease: eight women and three men between the age of 7 and 172 months. Four patients were classified as type I, two as type II and five as type III., Conclusions: a better understanding of the clinical features and diverse phenotypes in Mexican patients with Gaucher's disease will contribute to a timely diagnosis and a continuous, individualized treatment.
- Published
- 2012
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