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9. Lifestyle risk behavior and atherosclerotic cardiovascular risk: An analysis using the Korea National Health and Nutrition Examination Survey.

Author

Lee, Minwoo, Ahn, Hyo-Jeong, Lee, Su Jung, Kim, Pum-Jun, Kim, Chulho, Lee, Sang-Hwa, Sohn, Jong-Hee, and Lee, Jae-Jun

Subjects
AT-risk behavior, SEDENTARY behavior, HEALTH behavior, BAYESIAN analysis, CAUSAL inference
Abstract

Background: Clustering lifestyle risk behaviors is important for predicting cardiovascular disease risk. However, it is unclear which behavior mediates other ones to influence cardiovascular disease risk. We aimed to assess the causal inference of each lifestyle risk behavior for the atherosclerotic cardiovascular disease (ASCVD) risk of the general population. Methods: We performed a Bayesian network mediation analysis using data from the Korea National Health and Nutrition Examination Survey from 2014 to 2019. The main exposure was a combination of lifestyle risk behaviors including unhealthy weight, heavy alcohol consumption, inadequate sleep, physical inactivity, excessive sodium intake, and current smoking among subjects 40 to 79 years of age. The high risk of ASCVD (≥7.5% for the 10-year risk) was assessed using logistic regression, Bayesian networks, and structural equational models to examine the causal relationships between these six lifestyle risk behaviors. Results: Among all participants, the most prevalent lifestyle risk behavior for those at high risk for ASCVD was excessive sodium intake (95.6%), followed by inadequate sleep (49.9%) and physical inactivity (43.8%). Older age (65–79 years) and male sex were directly associated with a high risk for ASCVD. Physical inactivity, current smoking, excessive sodium intake, and unhealthy weight indirectly mediated the effects of older age (8.2% of the older age) and male sex (39.9% of males) to high ASCVD risk. Physical inactivity, current smoking, excessive sodium intake, and unhealthy weight particularly mediated the high ASCVD risk sequentially. Heavy alcohol consumption and inadequate sleep were not directly associated with high ASCVD risk and did not indirectly mediate the effects of older age and males on the high ASCVD risk. Conclusion: Lifestyle risk behaviors mediated the atherosclerotic cardiovascular disease risk in a different manner. Especially, physical inactivity preceded current smoking, excessive sodium intake, and unhealthy weight in relation to high ASCVD risk, and this causal relationship was different according to age and sex. Therefore, tailored strategies according to specific target populations may be needed to effectively reduce the high ASCVD risk. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Influence of Age and Sex on Post-Craniotomy Headache.

Author

Kim, Jong-Ho, Han, Sung-Woo, Kwon, Young-Suk, Lee, Jae-June, and Sohn, Jong-Hee

Subjects
AGE differences, DATA warehousing, SURGICAL complications, WOMEN patients, MULTIVARIATE analysis
Abstract

Post-craniotomy headache (PCH) is a common postoperative complication, and some of these patients progress to chronic PCH (CPCH). We aimed to identify clinical variables associated with PCH and its progression to CPCH, especially possible associations between age and sex differences. Therefore, we examined clinical information on PCH using the Clinical Data Warehouse over 10 years. Of the 1326 patients included, 927 patients (69.9%) experienced PCH. In multivariate analysis for PCH, age was inversely related to risk (p = 0.003), and being female showed a significant association with an increased risk of PCH (p = 0.002). There was also a significant inverse relationship between age and severity of the worst headache, with younger female patients reporting greater severity of the worst headache (p < 0.001). Of the 927 patients who experienced PCH, 319 (34.4%) progressed to CPCH. Sex was a significant factor, with females having a higher risk of developing CPCH compared to males (p < 0.001). In addition, the presence of preoperative headaches significantly increased the risk of CPCH (p = 0.001). The occurrence of PCH is associated with younger age and female sex. In particular, female sex and preoperative headaches increased the risk of developing CPCH. These clinical factors should be considered in patients undergoing neurosurgery. [ABSTRACT FROM AUTHOR]

Published
2024
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15. An Analysis of the Determinants of the Health-Related Quality of Life in Asian Patients With Cluster Headaches During Cluster Periods Using the Time Trade-Off Method

Author

Kim, Soo-Kyoung, primary, Chu, Min Kyung, additional, Kim, Byung-Kun, additional, Chung, Pil-Wook, additional, Moon, Heui-Soo, additional, Lee, Mi Ji, additional, Choi, Yun-Ju, additional, Park, Jeong Wook, additional, Kim, Byung-Su, additional, Song, Tae-Jin, additional, Oh, Kyungmi, additional, Ahn, Jin-Young, additional, Sohn, Jong-Hee, additional, Lee, Kwang-Soo, additional, Park, Kwang-Yeol, additional, Chung, Jae Myun, additional, Chung, Chin-Sang, additional, and Cho, Soo-Jin, additional

Published
2024
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27. Impact of prior use of antiplatelet agents and non-vitamin K antagonist oral anticoagulants on stroke outcomes among endovascular-treated patients with high pre-stroke CHA2DS2-VASc score

Author

Kim, Chulho, Sohn, Jong-Hee, Lee, Minwoo, Kim, Yerim, Mo, Hee Jung, Oh, Mi Sun, Yu, Kyung-Ho, and Lee, Sang-Hwa

Abstract

BackgroundWe assessed the influence of prior non-vitamin K antagonist (NOAC) use on stroke outcomes after endovascular treatment (EVT) in patients at a high risk of stroke based on their pre-stroke CHA2DS2-VASc score, and compared them with those who did not use any antithrombotic (NAU) or antiplatelet (APT) agents.MethodsData were collected from a multicenter database comprising consecutive acute ischemic stroke patients who underwent EVT during a span of 103 months. We evaluated pre-stroke CHA2DS2-VASc scores in enrolled patients and measured instances of successful reperfusion and symptomatic hemorrhagic transformation (SHT) following EVT as the main outcome measures.ResultsAmong 12 807 patients with acute ischemic stroke, 3765 (29.4%) had a history of atrial fibrillation. Of these, 418 patients with CHA2DS2-VASc scores ≥2 received EVT alone. The prior NOAC group showed higher successful reperfusion rates compared with the prior NAU and APT groups (p=0.04). Multivariate analysis revealed that prior NOAC use increased the likelihood of successful reperfusion after EVT (OR [95% CI] 2.54 [1.34 to 4.83], p=0.004) and improved stroke outcomes, while the prior APT group did not. Furthermore, the prior NOAC use group was not associated with SHT after EVT. Propensity score matching confirmed these findings.ConclusionPrior use of NOAC is associated with improved outcomes in high-risk stroke patients (pre-stroke CHA2DS2-VASc score ≥2) undergoing EVT.

Published
2024
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29. Treatment pattern and response for cluster headache in Korea: A prospective multicenter observation study

Author

Lee, Mi Ji, primary, Park, Jeong Wook, additional, Chu, Min Kyung, additional, Moon, Heui-Soo, additional, Chung, Pil-Wook, additional, Chung, Jae Myun, additional, Sohn, Jong-Hee, additional, Kim, Byung-Kun, additional, Kim, Byung-Su, additional, Kim, Soo-Kyoung, additional, Song, Tae-Jin, additional, Choi, Yun-Ju, additional, Park, Kwang-Yeol, additional, Oh, Kyungmi, additional, Ahn, Jin-Young, additional, Lee, Kwang-Soo, additional, Bae, Dae Woong, additional, and Cho, Soo-Jin, additional

Published
2023
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34. Age-Related Variations in Postoperative Pain Intensity across 10 Surgical Procedures: A Retrospective Study of Five Hospitals in South Korea.

Author

Kim, Jong-Ho, Sohn, Jong-Hee, Lee, Jae-Jun, and Kwon, Young-Suk

Subjects
*SPINAL surgery, *POSTOPERATIVE pain, *OPERATIVE surgery, *PAIN perception, *LUMBAR vertebrae, *PATIENT-controlled analgesia
Abstract

Age-related differences in pain perception have been reported in various contexts; however, their impact on postoperative pain intensity remains poorly understood, especially across different surgical procedures. Data from five hospitals were retrospectively analyzed, encompassing patients who underwent 10 distinct surgical procedures. Numeric rating scale scores were used to assess the worst postoperative pain intensity during the 24 h after surgery. The multivariate linear regression model analyzed the relationship between age and pain intensity. Subgroup analyses were performed according to sex and patient-controlled analgesia (PCA). This study included 41,187 patients. Among the surgeries studied, lumbar spine fusion (β = −0.155, p < 0.001) consistently and significantly exhibited a decrease in worst postoperative pain with increasing age. Similar trends were observed in cholecystectomy (β = −0.029, p < 0.001) and several other surgeries; however, the results were inconsistent across all analyses. Surgeries with higher percentages of PCA administration had lower median worst-pain scores. In conclusion, age may affect postoperative pain intensity after specific surgeries; however, a comprehensive understanding of the complex interplay between age, surgical intervention, and pain intensity is required. Pain management strategies should consider various factors, including age-related variations. [ABSTRACT FROM AUTHOR]

Published
2023
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41. Suicidality and Its Risk Factor in Migraine Patients

Author

Seo, Jong-Geun, primary, Kim, Byun-Kun, additional, Chu, Min Kyung, additional, Cho, Soo-Jin, additional, Chung, Pil-Wook, additional, Moon, Heui-Soo, additional, Kim, Byung-Su, additional, Ahn, Jin-Young, additional, Sohn, Jong-Hee, additional, Chung, Jae-Myun, additional, Choi, Yun-Ju, additional, Moon, Hye-Jin, additional, and Park, Sung-Pa, additional

Published
2022
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48. sj-docx-1-eso-10.1177_23969873221144814 – Supplemental material for Effects of prior antiplatelet use on futile reperfusion in patients with acute ischemic stroke receiving endovascular treatment

Author

Sohn, Jong-Hee, Kim, Chulho, Lee, Minwoo, Kim, Yerim, Jung Mo, Hee, Yu, Kyung-Ho, and Lee, Sang-Hwa

Subjects
FOS: Clinical medicine, Cardiology, Medicine, 110904 Neurology and Neuromuscular Diseases
Abstract

Supplemental material, sj-docx-1-eso-10.1177_23969873221144814 for Effects of prior antiplatelet use on futile reperfusion in patients with acute ischemic stroke receiving endovascular treatment by Jong-Hee Sohn, Chulho Kim, Minwoo Lee, Yerim Kim, Hee Jung Mo, Kyung-Ho Yu and Sang-Hwa Lee in European Stroke Journal

Published
2022
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50. Diagnostic Delay and Its Predictors in Cluster Headache

Author

Kim, Byung-Su, primary, Chung, Pil-Wook, additional, Kim, Byung-Kun, additional, Lee, Mi Ji, additional, Chu, Min Kyung, additional, Ahn, Jin-Young, additional, Bae, Dae Woong, additional, Song, Tae-Jin, additional, Sohn, Jong-Hee, additional, Oh, Kyungmi, additional, Kim, Daeyoung, additional, Kim, Jae-Moon, additional, Park, Jeong Wook, additional, Chung, Jae Myun, additional, Moon, Heui-Soo, additional, Cho, Soohyun, additional, Seo, Jong-Geun, additional, Kim, Soo-Kyoung, additional, Choi, Yun-Ju, additional, Park, Kwang-Yeol, additional, Chung, Chin-Sang, additional, and Cho, Soo-Jin, additional

Published
2022
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