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23 results on '"Soden, Muriel"'

1. EVOLVE: The Australian Rheumatology Association’s ‘top five’ list of investigations and interventions doctors and patients should question

Author

Morrisroe, Kathleen, Nakayama, Ayano, Soon, Jason, Arnold, Mark, Barnsley, Les, Barrett, Claire, Brooks, Peter M., Hall, Stephen, Hanrahan, Patrick, Hissaria, Pravin, Jones, Graeme, Katikireddi, Veera S., Keen, Helen, Laurent, Rodger, Nikpour, Mandana, Poulsen, Katherine, Robinson, Philip, Soden, Muriel, Wood, Nigel, Cook, Nicola, Hill, Catherine, and Buchbinder, Rachelle

Published
2018
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7. Irish association for rheumatology & rehabilitation: Proceedings of annual general meeting, Friday 3rd November 1989, university college, Cork

Author

Murray, A., Lackson, J., Soden, M., Feighery, C., Quinn, Catherine, Mulpeter, K., Casey, E., Hassan, J., Bresnihan, B., Whelan, A., Jackson, J., McDonald, M., Jackson, F., Stinson, J., Tomlin, G., Soden, Muriel, Rooney, Madeleine, Yanni, G., Duff, G., O’Neill, T. W., King, G., Molony, J., Graham, I. M., Doherty, Eva, Yanna, G., Conroy, R. M., O’Sullivan, Margaret M., Amos, N., Williams, B. D., Adams, L. E., Carter, Janet M., Roberts, S. M., Wheeler, J., Hess, E. V., Mongey, A -B., Carter, J. M., Veale, D. J., Kavanagh, G., Fielding, J. F., FitzGerald, O., Veale, D., Leahy, A., Barton, J., McMahon, M., Bouchier-Hayes, D., Courtney, G., O’Dwyer, A., Casey, E. B., Ward, A., Kelleher, P., O’Connor, G., Regan, M., Foley Nolan, D., Barry, C., Coughlan, R. J., Foley-Nolan, D., Daly, C., Nelligan, M., Woods, F., Bolger, C., Byrne, P. J., Gorey, T., and Hennessy, T. P. J.

Published
1990
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11. Complementing a clinical trial with human-computer interaction: Patients' user experience with telehealth

Author

Jalil, Sakib, Myers, Trina, Atkinson, Ian, Soden, Muriel, Jalil, Sakib, Myers, Trina, Atkinson, Ian, and Soden, Muriel

Abstract

Background: The use of telehealth to monitor patients from home is on the rise. Telehealth technology is evaluated in a clinical trial with measures of health outcomes and cost-effectiveness. However, what happens between a technology and the patients is not investigated during a clinical trial—the telehealth technology remains as a “black box.” Meanwhile, three decades of research in the discipline of human-computer interaction (HCI) presents design, implementation, and evaluation of technologies with a primary emphasis on users. HCI research has exposed the importance of user experience (UX) as an essential part of technology development and evaluation. Objective: This research investigates the UX of patients with type 2 diabetes mellitus (T2D) with a telehealth in-home monitoring device to manage T2D from home. We investigate how the UX during a clinical trial can be researched and what a clinical trial can learn from HCI research. Methods: We adopted an ethnographic philosophy and conducted a contextual inquiry due to time limitations followed by semistructured interviews of 9 T2D patients. We defined the method as Clinical User-experience Evaluation (CUE). The patients were enrolled in a telehealth clinical trial of T2D; however, this research was an independent study conducted by information technologists and health researchers for a user-centered evaluation of telehealth. Results: Key analytical findings were that patients valued the benefits of in-home monitoring, but the current device did not possess all functionalities that patients wanted. The results include patients’ experiences and emotions while using the device, patients’ perceived benefits of the device, and how patients domesticated the device. Further analysis showed the influence of the device on patients’ awareness, family involvement, and design implications for telehealth for T2D. Conclusions: HCI could comp

Published
2019

12. Morphometric analysis of blood vessels in synovial membranes obtained from clinically affected and unaffected knee joints of patients with rheumatoid arthritis

Author

FitzGerald, O., Soden, Muriel, Yanni, Ghada, Robinson, R., and Bresnihan, B.

Subjects
Synovial membranes -- Medical examination, Rheumatoid arthritis -- Physiological aspects, Knee -- Abnormalities, Health
Abstract

A variety of cellular changes are associated with the synovitis (joint inflammation) of rheumatoid arthritis. These include thickening of the synovial lining, infiltration by immune cells, and proliferation of venules and capillaries (small blood vessels). This vascular proliferation may determine the rate of disease progression, probably by allowing migration of lymphocytes (immune cells usually associated with inflammation) into synovial tissue. The vessels are lined with tall endothelial cells similar to those normally found in healthy lymphoid tissues. Indices of vessel proliferation and endothelial cell tallness were evaluated in samples from 9 inflamed knees and 4 uninflamed knees of patients with untreated rheumatoid arthritis, and similar samples from 13 normal control autopsied subjects. Thickening of the synovial lining was observed in about two-thirds of the samples. Cell infiltration was found in about one-third of the samples. The level of blood vessels was significantly higher in inflamed knee joints than in normal knees, but not significantly different between inflamed and uninflamed arthritic knees. Levels of high endothelial-containing venules was highest in the inflamed knee joints, somewhat less in uninflamed arthritic knees (but not significantly so), and significantly less in the control knee samples. The report suggests that synovial lining thickening and cell infiltration can occur without medically apparent synovitis and is apparently not dependent on changes in synovial blood vessels. (Consumer Summary produced by Reliance Medical Information, Inc.)

Published
1991

13. Immunohistological analysis of the synovial membrane: search for predictors of the clinical course in rheumatoid arthritis

Author

Soden, Muriel, Rooney, Madeleine, Whelan, Alex, Feighery, Conleth, and Bresnihan, Barry

Subjects
Rheumatoid arthritis -- Development and progression, T cells -- Physiological aspects, Rheumatoid arthritis -- Prognosis, Health
Abstract

The course and outcome of rheumatoid arthritis is variable and often unpredictable. Many symptoms and characteristics of rheumatoid arthritis have been studied in an effort to better predict patients' outcomes. Histopathologic changes (disease-related cellular changes) may help to indicate worsening of disease, but have previously been thought to be difficult to study. However, good joint tissue samples were obtained from patients previously untreated for rheumatoid arthritis (RA), and results indicated that the course of the disease was reflected in levels of lymphocytes (immune system cells important in fighting infection). The presence of immune cells in synovial (joint) tissue from 57 patients with RA was studied and correlated with the disease course over three years. At the start of the study, the index of disease activity (IDA) correlated significantly with thickening of the synovial lining, infiltration by mononuclear (having one nucleus) immune cells, and the presence of T lymphocytes (T cells) containing a particular cell surface protein known as CD5. Patients were divided into two groups, one having milder disease during initial examinations, the other having more severe disease at that time. After one year, the IDA in patients with severe disease improved by 64 percent, while the other group improved by 13 percent. Synovial lining thickening correlated with medical status in the severe-disease group. After three years, synovial lining thickening correlated very significantly with medical status in patients with milder disease. Additionally in these patients, medical status correlated with levels of T cells that were positive for the CD5 protein. The report suggests that early lymphocyte infiltration may influence the course of RA, but the effects of disease-modifying drugs, usually used to treat more severe disease, on lymphocyte levels are unknown. (Consumer Summary produced by Reliance Medical Information, Inc.)

Published
1991

16. Irish Association For Rheumatology And Rehabilitation Annual General Meeting, Friday, Nov. 4Th At Beaumont Hospital: Proceedings of Meeting held on Friday, November 4th, 1988 at Beaumont Hospital, Dublin

Author

FitzGerald, O., Soden, Muriel, Robinson, R., Bresnihan, B., Yanni, G., Donoghue, J., Carmody, M., Fitzgerald, O., Taylor, A., McNamara, A., Golding, D. N., Naughton, M., Kavanagh, B., Ward, K., McKenna, T. J., Coffey, M., Hassan, J., Feighery, C., FitzGerald, M., Bell, A. L., Wilson, G., McCaigue, M. D., Markey, G. M., Ward, J., Simms, C., Morris, T. C. M., Middleton, D., Taggart, A. J., Kondowe, G., Middleton, D., Foley-Nolan, D., Ryan, M., Stack, J., Redmond, U., Coughlan, R. J., Barry, C., Ennis, J., Crerand, S., Mulpeter, K., Quinn, C., Casey, E., Cuffe, J., McDonald, M., Wright, P., Mulpepper, K., O’Connor, Patricia, Cervi, P., Murphy, Annette, Kelleher, P., Jackson, J. F., Mulcahy, F., Davies, M. G., Gaine, S. P., Thakore, J., Dowling, F., McInerney, D., O’Marcaigh, A. S., Tony, T., Hennessy, T. P., Rooney, Madeleine, Symons, J. A., Duff, G. W., Cogley, D., Wong, J., Quinlan, W., Whelan, A., and McGuinness, E.

Published
1989
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17. Irish Association of Rheumatology and Rehabilitation Proceeding of Meeting held at St Vincent’s Hospital on Friday 30th October, 1987

Author

Foley-Nolan, D., Deegan, R., Foley-Nolan, A., Hone, R., Barry, C., Coughlan, R. J., Quinlan, W., Wong-Chung, J., Doyle, J., Mulpeter, K., Quinn, Kate, Casey, E., Feighery, C., Quinn, Catherine, Hassan, J., Whelan, A., Bresnihan, B., Soden, Muriel, FitzGerald, M., Gaine, S., O’Laoide, R. M., Feeley, J., McInerney, D. P., O’Brien, Maura, Donohoe, N., Comerford, F. R., Rooney, Madeleine, O’Connor, D. P., Noones, D., Weir, D., Marron, P., Keane, C., McNicholl, Janet, Glynes, Deirdre, Hutchinson, Michael, Murray, Avril, and Jackson, John

Published
1988
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19. Royal Academy of Medicine in Ireland — Section of Medicine Proceedings of Registrar’s Prize Meeting, Wednesday 4th May, 1988

Author

McCormack, P. M. E., Cotter, T., O’Malley, K., Foley, D. P., Dunne, P., O’Brien, M., Crowe, J. P., O’Callaghan, T., Lennon, J., O’Brien, T., Soden, Muriel, Bresnihan, B., Duggan, J., Patchett, S., Enright, H., Afdhal, N., O’Connell, L., O’Donoghue, D. P., Tobin, A., Clarke, R., Graham, I., O’Morain, C., Keating, J., Burke, P., McDonald, G., Monson, J., Stephens, R., Corrigan, O., and Keeling, P. W. N.

Published
1988
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