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The article presents the results of studies of 79 patients with postcovid syndrome. It was shown that 59 patients of the main group who underwent the rehabilitation program had significantly more pronounced improvement in clinical indicators compared to the control group. The results obtained were confirmed by the tests of Stange and Genche., 1. 36. Benkalfate N, et al. Evaluation of the Post- COVID- 19 Functional Status (PCFS) Scale in a cohort of patients recovering from hypoxemic SARS- CoV- 2 pneumonia BMJ Open Resp Res 2022;9:e001136. doi:10.1136/bmjresp-2021-001136 2. COVID-19 Dashboard by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University (JHU). URL: https://gisanddata.maps.arcgis.com/ apps/dashboards/bda7594740fd40299423467b48e9ecf6 (дата обращения — 10.03.2021) 3. Carfì A, Bernabei R, et al. Persistent Symptoms in Patients After Acute COVID-19. JAMA. 2020; 324 (6): 603–605. DOI: 10.1001/jama.2020.12603 4. Huang C, Huang L, Wang Y, et al. 6-month consequences of COVID-19 in patients discharged from hospital: a cohort study. Lancet. 2021; 397 (10270): 220-232. DOI: 10.1016/ S0140-6736(20)32656-8 5. Jasim SA, Mahdi RS, Bokov DO, Najm MAA, Sobirova GN, Bafoyeva ZO, Taifi A, Alkadir OKA, Mustafa YF, Mirzaei R, Karampoor S./ The deciphering of the immune cells and marker signature in COVID-19 pathogenesis: An update //J Med Virol . 2022 Jul 14;10.1002/jmv.28000. doi: 10.1002/jmv.28000. 6. Karimov M.M., Sobirova G.N., Zargarova N.R. /Method of determining the intestinal microbiota in patents after COVID-19 //Art of medicine, USA. Vol.2 Iss 3. 2022 P 172-180 https://doi.org/10.5281/zenodo.7219791 7. Sobirova G.N., Bafoeva Z.A., Usmokhodjaeva A.A. /Clinical and biochemical parameters of patients with COVID-19 with impaired liver function before and after treatment //Medical Journal of young scientists №1 (06). P. 105-112 8. Sobirova G.N., Bafoeva Z. O., Karimov M. M. /Influence of metabolic syndrome components in the course of covid-19 in patients with nonalcoholic fatty liver disease// MetabolismVolume 128, Supplement, March 2022, 155036 https://doi.org/10.1016/j.metabol.2021.155036

The article provides an overview of telemedicine research. The concepts of teletherapy, telerehabilitation, telediagnosis and teleconsultations are given. The advantages of information and communication methods in modern medicine are introduced. The necessity of further introduction of telemedicine in Uzbekistan is shown., References: 1. Hoenig H., Sanford Jha, Butterfield T., Griffiths P.S., Richardson P., Hargraves K. / Development of a teletechnology protocol for home rehabilitation. // Journal of Research and developments in the field of rehabilitation. 2006; 43(2):287–298. 2. https://medicalchain.com/en 3. Hill AJ, Theodoros D.G., Russell T.G., Cahill L.M., Ward E.K., Clarke K.M. / System Internet based telerehabilitation for evaluation of motor speech disorders: pilot study. // American Journal of Speech and Language Pathology. 2006; 15(1):45–56. 4. Peretti A., Amenta F., Tayebati S.K., Nittari G., Mahdi S.S. /Telerehabilitation: Review of the State-of-the-Art and Areas of Application //JMIR Rehabil Assist Technol 2017; 4(2):e7 5. Maria Grazia Maggio, Rosaria De Luca, Alfredo Manuli & Rocco Salvatore Calabrò (2020) / The five 'W' of cognitive telerehabilitation in the Covid-19 era, // Expert Review of Medical Devices, 17:6, 473–475. 6. https://trueconf.ru/telemedicina.html#telemedicina-03 7. Alan C Lee /COVID-19 and the Advancement of Digital Physical Therapist Practice and Telehealth // Physical Therapy, Volume 100, Issue 7, July 2020, Pages 1054–1057. 8. https://trueconf.ru/telemedicina.html 9. Kim, S.W., Jeon, H.R., Youk, T. et al. /The nature of rehabilitation services provided to children with cerebral palsy: a population-based nationwide study. BMC Health Serv Res 19, 277 (2019). https://doi.org/10.1186/s12913-019-4111-4. 10. Feng X, Winters J. // Interactive framework for personalized computer-assisted neurorehabilitation. // IEEE Transactions on Information Technology in Biomedicine. 2007; 11(5):518–526. 11. Russell T.G., Buttrum P., Wootton R., Jull G.A. // Low-throughput telerehabilitation for total knee arthroplasty patients: preliminary results. /Journal of telemedicine and telemedicine. 2003; 9(2):S44–S47. 12. Martijn Scherrenberg, Matthias Wilhelm, Dominique Hansen, Heinz Völler, Véronique Cornelissen, Ines Frederix, Hareld Kemps, Paul Dendale /The future is now: a call for action for cardiac telerehabilitation in the COVID-19 pandemic from the secondary prevention and rehabilitation section of the European Association of Preventive Cardiology // European Journal of Preventive Cardiology, Volume 28, Issue 5, May 2021, Pages 524–540. 13. Jasim SA, Mahdi RS, Bokov DO, Najm MAA, Sobirova GN, Bafoyeva ZO, Taifi A, Alkadir OKA, Mustafa YF, Mirzaei R, Karampoor S./The deciphering of the immune cells and marker signature in COVID-19 pathogenesis: An update // J.Med Virol . 2022 Jul 14;10.1002/jmv.28000. doi: 10.1002/jmv.28000. Epub ahead of print. PMID: 35835586; PMCID: PMC9350195. С.1-21 14. Собирова Г.Н., Манзитова В. Ф., Махкамова З.М./Возможности применения телетерапии и телереабилитации в Узбекистане //Терапевтический вестник Узбекистана, №2, 2022. С. 220-222.

Studies have shown that the vast majority of respondents with symptoms of acid-related diseases of the gastrointestinal tract were residents of the city of Tashkent. At the primary care level, in most cases, the diagnosis of chronic gastritis is made without appropriate confirmation. Appointment of the drug "Gastritol" to patients contributed to the pronounced relief of pain and postprandial functional dyspepsia syndromes, which indicates its high therapeutic efficacy., References: 1. Drossman D.A., Hasler W.L. Rome IV –Functional disorders: disorders of gut-brain interaction. Gastroenterology2016; 150(6):1257-61. 2. Pimanov S.I., Silivonchik N.N. Rome IV recommendations for diagnosis and treatment functional gastroenterological disorders. A guide for doctors.-М., 2016.-160 с. 3. Functional dyspepsia impacts absenteeism and direct and indirect costs // Brook R.A., Kleinman N.L., Choung R.S. et al. //Clin Gastroenterol Hepatol. 2010. Vol. 8. Р. 498–503. 4. Functional dyspepsia delayed gastric emptying and impaired quality of life // Talley N.J., Locke G.R., Lahr B.D. et al. // Gut. 2006. Vol. 23. P. 923–936. 5. Koroy P.V. Functional dyspepsia. Young Scientist Bulletin Volume: 12. Number: 1 Year: 2016 С. 40-45. 6. Pike B.L., Porter C.K., Sorrell T.J., Riddle M. S. Acute gastroenteritis and the risk of functional dyspepsia: a systematic review and meta-analysis // Am J Gastroenterol. 2013 Oct. Vol. 108 (10). Р. 1558–1563. 7. Makhov V.M., Romasenko L.V., Kashevarova S.S., Sheptak N.N. Multifactoriality of the clinical picture of functional dyspepsia // BC. 2012. No. 15, pp. 778–781. 8. Review article: current treatment and management of functional dyspepsia // Lacy BE, Talley NJ, Locke GR et all. //Aliment Pharmacol. Ther. 2012. Vol. 36. Р. 3–15.

The article presents the results of the anti-inflammatory efficacy of the new generation protease inhibitor ulinastatin in the treatment of exacerbation of chronic pancreatitis of moderate severity. It is shown that exacerbation of chronic pancreatitis of alimentary, alcoholic and biliary etiology was expressed by abdominal pain and dyspeptic symptoms. An increase in the level of serum aminotransferases, bilirubin and alpha amylase was noted, which was accompanied by a significant increase in the activity of pro-inflammatory cytokines. The use of ulinastatin in the complex of pharmacotherapy of chronic pancreatitis contributed to the effective relief of exacerbation of pancreatitis, which was due to the anticytokine effect of the drug., {"references":["1.\tБелякова С.В. Социально-демографическая и клиническая характеристика больных хроническим панкреатитом в Московской области. Дис. Канд. Наук., Москва. 2019. С.1-149.","2.\tSingh VK, Yadav D, Garg PK. Diagnosis and Management of Chronic Pancreatitis: A Review. JAMA. 2019 Dec 24;322(24):2422-2434. doi: 10.1001/jama.2019.19411. PMID: 31860051.","3.\tKarimov M.M., Zufarov P.S., Sobirova G.N., Pulatova N.I., Aripdjanova Sh.S. // Ulinastatin in the conservative therapy of chronic pancreatitis/ Central Asian Journal of Medicine 2, 2022 P. 54-61\t.","4.\tGlobal incidence and mortality of pancreatic diseases: a systematic review, meta-analysis, and meta-regression of population-based cohort studies / Xiao AY, Tan ML, Wu LM [et al.] // Lancet Gastroenterol Hepatol . –2016. - Vol. 1(1). – P. 45-55.","5.\tThe incidence and aetiology of acute pancreatitis across Europe / S E Roberts, S. Morrison-Rees, A. John [et al.]// Pancreatology. –2017. - Vol. 17, No. 2. – P. 155-165.","6.\tUpdate on pathogenesis and clinical management of acute pancreatitis / DM Cruz- Santamaría, C. Taxonera, M. Giner // World J Gastrointest Pathophysiol. - 2012. - Vol . 3(3). – P. 60-70.","7.\tRole of Ulinastatin, a trypsin inhibitor, in severe acute pancreatitis in critical care setting: A ¬¬retrospective analysis. / Lagoo JY, D'Souza MC, Kartha A., Kutappa AM // J Crit Care. - 2018. - No. 45. - P. 27-32.","8.\tUlinastatin ameliorates tissue damage of severe acute pancreatitis through modulating regulatory T cells / Pan Y., Fang H., Lu F. [et al.] // J Inflamm (Lond). - 2017. -Vol.14.–P.7. doi: 10.1186/s12950-017-0154-7.","9.\tEffect of ulinastatin on serum levels of tumor necrosis factor-α, P-selectin, and thrombin-antithrombin complex in young rats with sepsis / Liu Y., Wu XH // Zhongguo Dang Dai ErKe Za Zhi. - 2017. - Vol. 19(2). – P. 237-241."]}