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14 results on '"Snezhkova, Elisaveta A."'

7. Orally Administered Activated Charcoal as a Medical Countermeasure for Acute Radiation Syndrome in Rats

Author

Universidad de Alicante. Departamento de Química Inorgánica, Universidad de Alicante. Instituto Universitario de Materiales, Snezhkova, Elisaveta, Rodionova, Natalia, Bilko, Dennis, Silvestre-Albero, Joaquín, Sydorenko, Alexey, Yurchenko, Olga, Pakharenko, Marharyta, Alavijeh, Mo, Bardakhivska, Kvitoslava, Riabchenko, Natalia, Nikolaev, Vladimir, Universidad de Alicante. Departamento de Química Inorgánica, Universidad de Alicante. Instituto Universitario de Materiales, Snezhkova, Elisaveta, Rodionova, Natalia, Bilko, Dennis, Silvestre-Albero, Joaquín, Sydorenko, Alexey, Yurchenko, Olga, Pakharenko, Marharyta, Alavijeh, Mo, Bardakhivska, Kvitoslava, Riabchenko, Natalia, and Nikolaev, Vladimir

Abstract

Activated charcoal (AC) can be taken orally as enterosorbent for treatment of pathological states related to exogenous and endogenous intoxications. Synthesized granulated AC with a highly developed active surface (SBET ~2700 m2/g) was used as a medical countermeasure (MCM) to acute radiation sickness (ARS) in rats after total body X-ray irradiation. AC demonstrates positive results in ARS treatment, as expressed in, (i) a decrease in body weight loss, (ii) a protection of bone marrow (BM) cells colony formation capacity, (iii) a reduction of BM chromosomal aberrations and small intestine and spleen tissue damage, (iv) an amelioration of white blood cell count, and (v) a mitigation of superoxide ion generation rate in the liver. AC oral prescription seems to be perspective modality of ARS treatment.

Published
2021

8. Orally administered activated charcoal as a medical countermeasure for acute radiation syndrome in rats

Author

Snezhkova, Elisaveta, Rodionova, Natalia, Bilko, Denys, Silvestre-Albero, Joaquín, Sydorenko, Alexey, Yurchenko, Olga, Pakharenko, Marharyta, Alavijeh, Mohammad, Bardakhivska, Kvitoslava, Riabchenko, Natalia, Nikolaev, Volodymyr, Snezhkova, Elisaveta, Rodionova, Natalia, Bilko, Denys, Silvestre-Albero, Joaquín, Sydorenko, Alexey, Yurchenko, Olga, Pakharenko, Marharyta, Alavijeh, Mohammad, Bardakhivska, Kvitoslava, Riabchenko, Natalia, and Nikolaev, Volodymyr

Abstract

Activated charcoal (AC) can be taken orally as enterosorbent for treatment of pathological states related to exogenous and endogenous intoxications. Synthesized granulated AC with a highly developed active surface (SBET ~2700 m2/g) was used as a medical countermeasure (MCM) to acute radiation sickness (ARS) in rats after total body X-ray irradiation. AC demonstrates positive results in ARS treatment, as expressed in, (i) a decrease in body weight loss, (ii) a protection of bone marrow (BM) cells colony formation capacity, (iii) a reduction of BM chromosomal aberrations and small intestine and spleen tissue damage, (iv) an amelioration of white blood cell count, and (v) a mitigation of superoxide ion generation rate in the liver. AC oral prescription seems to be perspective modality of ARS treatment.

Published
2021

9. Orally Administered Activated Charcoal as a Medical Countermeasure for Acute Radiation Syndrome in Rats

Author

Snezhkova, Elisaveta, primary, Rodionova, Natalia, additional, Bilko, Dennis, additional, Silvestre-Albero, Joaquin, additional, Sydorenko, Alexey, additional, Yurchenko, Olga, additional, Pakharenko, Marharyta, additional, Alavijeh, Mo, additional, Bardakhivska, Kvitoslava, additional, Riabchenko, Natalia, additional, and Nikolaev, Vladimir, additional

Published
2021
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11. Effect of Primary and Secondary Beads of Carbon Enterosorbent on Haematological Parameters and Oxidative Stress Development Caused by Melphalan in Rats

Author

Shevchuk, Oksana, primary, Snezhkova, Elisaveta, additional, Sarnatskaya, Veronika, additional, Mikhailenko, Victor, additional, Glavin, Alexei, additional, Makovetska, Lyudmyla, additional, Bardakhivska, Kvitoslava, additional, Birchenko, Inna, additional, Kozynchenko, Oleksandr, additional, and Nikolaev, Volodymyr, additional

Published
2019
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