18 results on '"Sneed RS"'
Search Results
2. Peer navigation intervention for individuals with serious mental illness reentering the community after jail incarceration: a qualitative case study.
- Author
-
Hailemariam M, Weinstock LM, Sneed RS, Taylor B, Corrigan PW, and Johnson JE
- Abstract
Background: Criminal legal system-involved individuals with serious mental illness (SMI) experience more challenges accessing mental health and other community services than those without a history of criminal legal system involvement. A formative qualitative study was conducted to explore feasibility and acceptability and inform the adaptation of a mental health peer navigation intervention for individuals with SMI reentering the community after jail incarceration., Methods: In-depth qualitative interviews and focus-group discussions were conducted with mental health peer navigators (i.e., certified mental health peer support specialists, peer recovery coaches) and individuals with lived experience of SMI and criminal legal system involvement (N = 20 total). Data were analyzed using applied thematic analysis., Results: Four major themes emerged: (1) Feasibility and acceptability of peer-provided services: all participants reported that peer navigation services would be feasible and acceptable for individuals with SMI reentering the community after jail incarceration; (2) roles of peer navigators in addressing barriers to care: peers can address barriers to care experienced during community reentry and contribute towards service linkage/engagement; (3) shared identity and combating stigma: having a shared identity with peer navigators may minimize the impact of stigma and make it easier for clients with multiple marginalized identities to seek support; and (4) peer navigator skills and recommendations for the planned program: essential peer navigation skills include authenticity, reliability, active listening, advocacy, trauma-informed care, motivational interviewing, and empathy. Recommendations for the planned program include initiating services while clients are in custody, emphasizing the voluntary nature of peer support, knowing the limits of a peer navigation intervention, and offering support for peer navigators while on the job., Conclusion: Participants saw peer navigation services for individuals with SMI with criminal legal system involvement as potentially feasible and acceptable. Such programs may enhance their impact by offering supportive supervision, emphasizing the voluntary nature of the service, and acknowledging recovery as a self-directed endeavor., (© 2024. The Author(s).)
- Published
- 2024
- Full Text
- View/download PDF
3. Coordinated Care Experiences Among Middle-Aged and Older Adults With Multiple Chronic Conditions: Characteristics, Correlates, and Consequences for Health and Healthcare Utilization.
- Author
-
Qin W, Kalesnikava V, Dang L, Sneed RS, Messina R, Rucci P, and Mezuk B
- Subjects
- Humans, Male, Female, Aged, Middle Aged, Patient Satisfaction, Cohort Studies, Health Status, Aged, 80 and over, Longitudinal Studies, Patient Acceptance of Health Care statistics & numerical data, Multiple Chronic Conditions therapy
- Abstract
Background and Objectives: Although coordinated care (CC) seeks to improve patient experiences and ultimately health outcomes, evidence from empirical research on the impacts of CC is mixed. This study examined the relationship between CC and healthcare outcomes over a 4-year period among older adults with multiple chronic conditions., Research Design and Methods: This observational cohort study is based on data from the 2016-2020 Health and Retirement Study. Analysis is limited to respondents with 2+ chronic conditions who completed an experimental module on CC in 2016 (n = 906). Three domains of CC were assessed: perceptions, informal (family/friends) and formal (healthcare staff) tangible support, and technical support (using a "patient portal"). The longitudinal relationship between CC and health (e.g., pain, functioning, and self-rated health [SRH]) and healthcare (e.g., doctor visits, hospitalization, and care satisfaction) outcomes was investigated using mixed-effects models., Results: Better perceptions of CC were associated with lower odds of ADL limitations (Odds ratio [OR] = 0.91; 95% CI = 0.84-0.99) and greater satisfaction with care (B = 0.04, 95% CI = 0.02-0.06). Receipt of more informal tangible support was associated with 1.34 higher odds of ADL limitations (95% CI = 1.19-1.51) and 1.74 higher odds of hospitalization (95% CI = 1.07-1.21). Use of technical support was associated with better SRH and greater satisfaction with care., Discussion and Implications: The longitudinal relationship between CC and health is multifaceted. Although positive perceptions and more technical support have beneficial effects on health outcomes, higher utilization of tangible support may reflect a higher demand among older adults with more complex healthcare needs., (© The Author(s) 2024. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)
- Published
- 2024
- Full Text
- View/download PDF
4. Chronic Disease, Functional Limitations, and Workforce Participation Among Medicaid Enrollees Over 50: The Potential Impact of Medicaid Work Requirements Post-COVID-19.
- Author
-
Sneed RS, Stubblefield A, Gardner G, Jordan T, and Mezuk B
- Subjects
- United States, Humans, Pandemics, Cost of Illness, Chronic Disease, Medicaid, COVID-19
- Abstract
From 2018-2020, 19 states enacted Medicaid work requirements as a strategy for reducing program enrollment and overall cost. While these requirements were later rescinded, strategies to reduce Medicaid costs are likely to reemerge as states attempt to recover economically from the COVID-19 pandemic. Here, we evaluated the impact of Medicaid work requirements on adults aged > 50, a group that likely faces significant age-related chronic disease burden. Using 2016 Health and Retirement Study data, we evaluated the chronic disease burden of adult Medicaid beneficiaries aged 51-64 years ( n = 1460) who would be at risk of losing their Medicaid coverage due to work requirements. We compared Medicaid beneficiaries working <20 hours per week (i.e. those at risk of coverage loss) to those working at least 20 hours per week on eight chronic health conditions, adjusting for demographic characteristics. Among those with chronic health conditions, we also evaluated differences in disease severity based on hours worked per week. Among those working fewer than 20 hours per week, odds of disease were greater for seven of eight chronic conditions, including history of stroke (OR: 5.66; 95% CI: 2.22-14.43) and lung disease (OR: 3.79; 95% CI: 2.10-6.85). Further, those with greater disease severity were likely to work fewer hours. Thus, the introduction of Medicaid work requirements would likely result in coverage loss and lower access to care among older Medicaid beneficiaries with multiple chronic health conditions.
- Published
- 2024
- Full Text
- View/download PDF
5. Harnessing education and lifestyle change to support transitional health for returning citizens: a feasibility study protocol.
- Author
-
Sneed RS, El-Alamin L, Thrower M, Nadrowski J, and Habermehl K
- Abstract
Background: Exercise and healthy eating are known to reduce chronic disease risk; however, formerly incarcerated individuals (i.e., returning citizens) face significant social barriers when attempting to engage with existing community-based physical activity and nutrition programs. Given the high disease burden and unique educational needs of returning citizens, this proposed work fills an important gap in the support services currently offered to this population., Methods: This article describes a process for evaluating the feasibility and acceptability of a physical activity and nutrition intervention tailored to the needs of returning citizens via a partnership between an academic research organization and a community-based reentry program for returning citizens. Staff from the community-based reentry program will train four returning citizens as group fitness instructors and work with a nutritionist to design a 16-week nutrition education curriculum. Reentry program staff will enroll up to 15 formerly incarcerated adults (aged 18 +) in the exercise and nutrition program. Participants will take part in weekly nutrition classes led by the nutritionist and weekly group exercise classes led by a peer instructor. Research staff will evaluate program success in four domains: reach, preliminary effectiveness, implementation, and maintenance., Results: This feasibility study will allow us to design and test a program that can eventually be evaluated in a large, randomized trial. It also addresses the multitude of social determinants that impact the health of returning citizens and builds a framework for program sustainability. Individuals recruited as fitness trainers will acquire skills and certifications that may be used to sustain physical fitness activities within the reentry program., Conclusions: This feasibility study will test our ability to address social determinants that impact the health of returning citizens through a peer-led physical activity and nutrition programming. In the long term, study results may inform development and implementation of reentry programming and policy on a wider scale., (© 2023. BioMed Central Ltd., part of Springer Nature.)
- Published
- 2023
- Full Text
- View/download PDF
6. Factors Associated With Health Care Delays Among Adults Over 50 During the COVID-19 Pandemic.
- Author
-
Chan ACY and Sneed RS
- Subjects
- Aged, Humans, Delivery of Health Care, Ethnicity, Pandemics, United States, White, Black or African American, Hispanic or Latino, COVID-19 epidemiology, Time-to-Treatment
- Abstract
Background: Adults over 50 have high health care needs but also face high coronavirus disease 2019 (COVID-19)-related vulnerability. This may result in a reluctance to enter public spaces, including health care settings. Here, we examined factors associated with health care delays among adults over 50 early in the COVID-19 pandemic., Methods: Using data from the 2020 wave of the Health and Retirement Study (N = 7 615), we evaluated how race/ethnicity, age, geographic region, and pandemic-related factors were associated with health care delays., Results: In our sample, 3 in 10 participants who were interviewed from March 2020 to June 2021 reported delays in medical or dental care in the early stages of the COVID-19 pandemic. Non-Hispanic Whites (odds ratio [OR]: 1.37; 95% confidence interval [CI]: 1.19-1.58) and those of other racial/ethnic backgrounds (OR: 1.31; 95% CI: 1.02-1.67) delayed care more than Non-Hispanic Blacks. Other factors associated with delayed care included younger age, living in the Midwest or West, knowing someone diagnosed with or who died from COVID-19, and having high COVID-19-related concerns. There were no differences in care delays among adults aged > 70; however, among those ≤ 70, those who knew someone diagnosed with COVID-19 were more likely to delay care than those who did not. Additionally, among those ≤ 70, Non-Hispanic Whites and those of other racial/ethnic backgrounds delayed care more than Non-Hispanic Blacks and Hispanics., Conclusions: There is considerable heterogeneity in care delays among older adults based on age, race/ethnicity, and pandemic-related factors. As the pandemic continues, future studies should examine whether these patterns persist., (© The Author(s) 2022. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.)
- Published
- 2023
- Full Text
- View/download PDF
7. Psychology Meets Biology in COVID-19: What We Know and Why It Matters for Public Health.
- Author
-
Jones EJ, Ayling K, Wiley CR, Geraghty AWA, Greer AL, Holt-Lunstad J, Prather AA, Schreier HMC, Silver RC, Sneed RS, Marsland AL, Pressman SD, and Vedhara K
- Abstract
Psychosocial factors are related to immune, viral, and vaccination outcomes. Yet, this knowledge has been poorly represented in public health initiatives during the COVID-19 pandemic. This review provides an overview of biopsychosocial links relevant to COVID-19 outcomes by describing seminal evidence about these associations known prepandemic as well as contemporary research conducted during the pandemic. This focuses on the negative impact of the pandemic on psychosocial health and how this in turn has likely consequences for critically relevant viral and vaccination outcomes. We end by looking forward, highlighting the potential of psychosocial interventions that could be leveraged to support all people in navigating a postpandemic world and how a biopsychosocial approach to health could be incorporated into public health responses to future pandemics., Competing Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article., (© The Author(s) 2022.)
- Published
- 2023
- Full Text
- View/download PDF
8. Examining Community Engagement Research Strategies Used in Flint, Michigan: The Church Challenge.
- Author
-
Key K, Calvin K, Jordan T, Sneed RS, Bailey S, Jefferson B, Brewer A, Vincent-Doe A, Scott JB, Saunders P, and Johnson-Lawrence V
- Subjects
- Humans, Black or African American, Michigan, Drinking Water, Water Pollution, Community-Based Participatory Research, Research Design
- Abstract
Background: The ways in which researchers may need to adapt traditional community-based participatory research engagement strategies during ongoing community trauma are understudied. We describe our efforts to engage the Flint, Michigan community in community-based participatory research in the aftermath of the Flint Water Crisis., Objectives: This manuscript describes 1) recruitment strategies selected before the Flint Water Crisis, 2) engagement lessons learned in the context of the Flint Water Crisis, and 3) barriers and facilitators encountered while engaging African American churches., Methods: Researchers collaborated with community partners to engage and recruit a traumatized Flint community into the Church Challenge, a multilevel intervention to reduce chronic disease burden., Lessons Learned: Recruitment and engagement strategies must be flexible, innovative, and may require nontraditional methods., Conclusions: Flexibility and adaptability are crucial for engaging with a traumatized community. Community-based participatory research work in traumatized communities must acknowledge and respond to community trauma to be successful.
- Published
- 2023
- Full Text
- View/download PDF
9. The Implications of Intergenerational Relationships for Minority Aging: a Review of Recent Literature.
- Author
-
Sneed RS and Chan ACY
- Abstract
Purpose of Review: This study aims to understand how intergenerational relationships impact minority aging in the USA. We reviewed studies published in the last 5 years that examine both familial and non-familial intergenerational relationships., Recent Findings: Intergenerational relationships can have positive and negative implications for minority aging. Minority older adults benefit most from these relationships when they increase social interaction and/or offer social support by reducing acculturative stress, providing emotional closeness, or increasing access to tangible resources. At the same time, these relationships can be sources of strain as they lead to burden among already disadvantaged groups., Summary: Future studies should explore the impact of intergenerational relations among more diverse subgroups of older adults and identify mechanisms linking intergenerational relationships to health-related outcomes among minority older adults. Further, longitudinal cohort studies and randomized trials are needed to test mechanisms and evaluate the effectiveness of promising intergenerational interventions., Competing Interests: Conflict of InterestThe authors declare no competing interests., (© The Author(s), under exclusive licence to Springer Nature Switzerland AG 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.)
- Published
- 2023
- Full Text
- View/download PDF
10. Developing and maintaining intergenerational relationships in an economically vulnerable community: findings from the Flint women's study.
- Author
-
Sneed RS, Hailemariam M, Key KD, Jordan T, Miller R, Richie F, Robinson D, Saddler S, Spencer B, Summers M, McCoy White J, and Johnson JE
- Subjects
- Female, Humans, Middle Aged, Caregivers, Employment
- Abstract
Few studies describe how community disadvantage impacts intergenerational relationships. Using interviews with women and service providers (n = 100), we explored benefits and challenges of intergenerational relationships in Flint, Michigan, an economically vulnerable community. Women valued relationships that increased social connections and generativity; however, few community resources promoted such relationships. Intergenerational relationships were important for leaving a social legacy in lieu of a meaningful economic legacy. Some middle-aged women are overwhelmed by caregiving, balancing employment while caring for multiple generations. Women desired intergenerational activities that include children and younger adult women. Further, caregiving programs should attend to the needs of middle-aged caregivers.
- Published
- 2022
- Full Text
- View/download PDF
11. What Factors Are Associated With Psychological Vulnerability and Resiliency Among Older Adults During the COVID-19 Pandemic?
- Author
-
Sneed RS and Krendl AC
- Subjects
- Aged, Humans, Mental Health, Pandemics, SARS-CoV-2, COVID-19 epidemiology
- Published
- 2022
- Full Text
- View/download PDF
12. Using Critical Race Theory to Understand Trial Participation Among Black Individuals With Systemic Lupus Erythematosus: A Qualitative Study of Patients and Caregivers.
- Author
-
Sneed RS, Mason M, Williams JN, Sinnette C, Taber K, Mancera-Cuevas K, Curry G, Canessa P, Ramsey-Goldman R, and Feldman CH
- Subjects
- Adult, Aged, Boston, Chicago, Female, Focus Groups, Humans, Lupus Erythematosus, Systemic diagnosis, Lupus Erythematosus, Systemic ethnology, Male, Middle Aged, Motivation, Qualitative Research, Race Factors, Trust, Black or African American psychology, Clinical Trials as Topic, Health Knowledge, Attitudes, Practice ethnology, Lupus Erythematosus, Systemic therapy, Patient Selection, Racism
- Abstract
Objective: Black patients with systemic lupus erythematous (SLE) experience greater disease incidence and severity than White patients, and yet they are underrepresented in SLE clinical trials. We applied Critical Race Theory to qualitatively explore the influence of racism on the underrepresentation of Black patients in SLE clinical trials and to develop a framework for future intervention., Methods: We conducted focus group sessions in Chicago and Boston with Black adults (ages ≥18 years) with SLE and their caregivers. We queried the participants about their knowledge regarding clinical trials, factors that might motivate or hinder trial participation, and how race and experiences of racism might impact clinical trial participation. Focus group responses were transcribed verbatim and analyzed thematically., Results: We held 4 focus groups (n = 31 participants); 20 participants had SLE, and 11 were caregivers. All participants were Black, 90% were women, and the mean age was 54 years. Qualitative analyses revealed several themes that negatively impact trial participation, including mistrust related to racism, concerns about assignment to placebo groups, strict study exclusion criteria, and SLE-related concerns. Factors that motivated trial participation included recommendations from physicians and reputable institutions, a desire to help the greater good, and culturally sensitive marketing of trials., Conclusion: Actions to improve clinical trial participation among Black individuals should focus on reframing how trial information is presented and disseminated and on reevaluating barriers that may restrict trial participation. Additionally, researchers must acknowledge and respond to the presence of racial bias in health care. Community-academic partnerships may help build trust and reduce fears of mistreatment among Black individuals with SLE., (© 2021, American College of Rheumatology.)
- Published
- 2021
- Full Text
- View/download PDF
13. Social and psychological consequences of the COVID-19 pandemic in African-American communities: Lessons from Michigan.
- Author
-
Sneed RS, Key K, Bailey S, and Johnson-Lawrence V
- Subjects
- Adult, COVID-19, Humans, Michigan ethnology, Pandemics, Psychological Trauma therapy, Black or African American ethnology, Community Mental Health Services, Coronavirus Infections ethnology, Grief, Healthcare Disparities ethnology, Mental Health Services, Pneumonia, Viral ethnology, Psychological Trauma ethnology, Religion and Psychology
- Abstract
The mental health consequences of the COVID-19 pandemic are particularly relevant in African-American communities because African-Americans have been disproportionately impacted by the disease, yet they are traditionally less engaged in mental health treatment compared with other racial groups. Using the state of Michigan as an example, we describe the social and psychological consequences of the pandemic on African-American communities in the United States, highlighting community members' concerns about contracting the disease, fears of racial bias in testing and treatment, experiences of sustained grief and loss, and retraumatization of already-traumatized communities. Furthermore, we describe the multilevel, community-wide approaches that have been used thus far to mitigate adverse mental health outcomes within our local African-American communities. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
- Published
- 2020
- Full Text
- View/download PDF
14. Behavioral Health Concerns During the Flint Water Crisis, 2016-2018.
- Author
-
Sneed RS, Dotson K, Brewer A, Pugh P, and Johnson-Lawrence V
- Subjects
- Humans, Michigan epidemiology, Water, Water Supply
- Abstract
In April 2014, a switch in the municipal water source for Flint, Michigan resulted in contamination of the water supply with lead, a toxic health hazard. Since the onset of this Flint Water Crisis, there has been considerable interest in behavioral health outcomes for Flint residents. In 2016, local, state, and federal partners began to collect household-level, emergency-related behavioral and physical health information in Flint. Follow-up data were conducted in 2017 and 2018 to evaluate changes in behavioral health outcomes and the effectiveness of behavioral health programming. From 2016 to 2018, Flint residents demonstrated improvements across several behavioral health outcomes; however, residents continued to experience crisis-related stress, including fear that the crisis would never be fixed. Future behavioral health efforts in the city should focus on continuing to provide behavioral health services to residents and restoring trust within the community.
- Published
- 2020
- Full Text
- View/download PDF
15. Grandparent Caregiving, Race, and Cognitive Functioning in a Population-Based Sample of Older Adults.
- Author
-
Sneed RS and Schulz R
- Subjects
- Black or African American statistics & numerical data, Aged, Caregivers statistics & numerical data, Female, Humans, Longitudinal Studies, Male, White People statistics & numerical data, Black or African American psychology, Caregivers psychology, Cognition physiology, Grandparents psychology, White People psychology
- Abstract
Objective: The aim of this study was to evaluate the association between noncustodial grandparent caregiving and cognition using the Health and Retirement Study (HRS), a population-based study of older adults. Method: Participants were White and African American grandparents aged ≥65 years. Only noncustodial grandparents who reported not living with their grandchildren over the three waves were included in our analyses. Grandparent caregiving status and cognition were assessed in 2006, 2008, and 2010. Analyses controlled for demographics, baseline health, depressive symptoms, and baseline cognition. Results: Both the number of waves of grandparent caregiving and the total number of grandparent caregiving hours across the three waves were associated with better cognitive functioning at 4-year follow-up in 2010. Associations were observed among Whites, but not among African Americans. Discussion: This study uses longitudinal data to evaluate the association between grandparent caregiving and cognitive functioning. Findings suggest that providing care may be beneficial for some grandparents.
- Published
- 2019
- Full Text
- View/download PDF
16. Negative social interactions and incident hypertension among older adults.
- Author
-
Sneed RS and Cohen S
- Subjects
- Age Distribution, Aged, Aged, 80 and over, Female, Humans, Incidence, Male, Middle Aged, Prospective Studies, Risk Factors, Sex Distribution, Emotions, Hypertension epidemiology, Interpersonal Relations
- Abstract
Objective: To determine if negative social interactions are prospectively associated with hypertension among older adults., Method: This is a secondary analysis of data from the 2006 and 2010 waves of the Health and Retirement Study, a survey of community-dwelling older adults (age > 50 years). Total average negative social interactions were assessed at baseline by averaging the frequency of negative interactions across 4 domains (partner, children, other family, friends). Blood pressure was measured at both waves. Individuals were considered to have hypertension if they reported use of antihypertensive medications, had measured average resting systolic blood pressure of 140 mmHg or higher, or measured average resting diastolic blood pressure of 90 mmHg or higher. Analyses excluded those who were hypertensive at baseline and controlled for demographics, personality, positive social interactions, and baseline health., Results: Twenty-nine percent of participants developed hypertension over the 4-year follow-up. Each 1-unit increase in the total average negative social interaction score was associated with a 38% increased odds of developing hypertension. Sex moderated the association between total average negative social interactions and hypertension, with effects observed among women but not men. The association of total average negative interactions and hypertension in women was attributable primarily to interactions with friends, but also to negative interactions with family and partners. Age also moderated the association between total average negative social interactions and hypertension, with effects observed among those ages 51-64 years, but not those ages 65 or older., Conclusion: In this sample of older adults, negative social interactions were associated with increased hypertension risk in women and the youngest older adults., (PsycINFO Database Record (c) 2014 APA, all rights reserved.)
- Published
- 2014
- Full Text
- View/download PDF
17. A prospective study of volunteerism and hypertension risk in older adults.
- Author
-
Sneed RS and Cohen S
- Subjects
- Aged, Aged, 80 and over, Female, Health Surveys, Humans, Male, Middle Aged, Prospective Studies, Risk Assessment, Time Factors, Hypertension epidemiology, Volunteers statistics & numerical data
- Abstract
The purpose of the current study was to determine whether volunteerism is prospectively associated with hypertension risk among older adults. Participants provided data during the 2006 and 2010 waves of the Health and Retirement Study, a longitudinal panel survey using a nationally representative sample of community-dwelling older adults (age > 50 years). Volunteerism and blood pressure were measured at baseline and again 4 years later. Analyses excluded individuals hypertensive at baseline and controlled for age, race, sex, education, baseline systolic/diastolic blood pressure, and major chronic illnesses. Those who had volunteered at least 200 hr in the 12 months prior to baseline were less likely to develop hypertension (OR = 0.60; 95% CI [0.40, 0.90]) than nonvolunteers. There was no association between volunteerism and hypertension risk at lower levels of volunteer participation. Volunteering at least 200 hr was also associated with greater increases in psychological well-being (B = 0.99, β = .05, p = .006) and physical activity (B = 0.21, β = .05, p = .04) compared with nonvolunteers; however, these factors did not explain the association of volunteerism with hypertension risk., (PsycINFO Database Record (c) 2013 APA, all rights reserved.)
- Published
- 2013
- Full Text
- View/download PDF
18. Multistate outbreak of Fusarium keratitis associated with use of a contact lens solution.
- Author
-
Chang DC, Grant GB, O'Donnell K, Wannemuehler KA, Noble-Wang J, Rao CY, Jacobson LM, Crowell CS, Sneed RS, Lewis FM, Schaffzin JK, Kainer MA, Genese CA, Alfonso EC, Jones DB, Srinivasan A, Fridkin SK, and Park BJ
- Subjects
- Adult, Case-Control Studies, DNA, Fungal, Disease Outbreaks, Drug Packaging, Equipment Contamination, Female, Humans, Male, Middle Aged, United States epidemiology, Contact Lens Solutions, Fusarium genetics, Fusarium isolation & purification, Keratitis epidemiology, Keratitis microbiology, Mycoses epidemiology, Mycoses etiology
- Abstract
Context: Fusarium keratitis is a serious corneal infection, most commonly associated with corneal injury. Beginning in March 2006, the Centers for Disease Control and Prevention received multiple reports of Fusarium keratitis among contact lens wearers., Objective: To define the specific activities, contact lens hygiene practices, or products associated with this outbreak., Design, Setting, and Participants: Epidemiological investigation of Fusarium keratitis occurring in the United States. A confirmed case was defined as keratitis with illness onset after June 1, 2005, with no history of recent ocular trauma and a corneal culture growing Fusarium species. Data were obtained by patient and ophthalmologist interviews for case patients and neighborhood-matched controls by trained personnel. Available Fusarium isolates from patients' clinical and environmental specimens were genotyped by multilocus sequence typing. Environmental sampling for Fusarium was conducted at a contact lens solution manufacturing plant., Main Outcome Measures: Keratitis infection with Fusarium species., Results: As of June 30, 2006, we identified 164 confirmed case patients in 33 states and 1 US territory. Median age was 41 years (range, 12-83 years). Corneal transplantation was required or planned in 55 (34%). One hundred fifty-four (94%) of the confirmed case patients wore soft contact lenses. Forty-five case patients and 78 controls were included in the case-control study. Case patients were significantly more likely than controls to report using a specific contact lens solution, ReNu with MoistureLoc (69% vs 15%; odds ratio, 13.3; 95% confidence interval, 3.1-119.5). The prevalence of reported use of ReNu MultiPlus solution was similar between case patients and controls (18% vs 20%; odds ratio, 0.7; 95% confidence interval, 0.2-2.8). Fusarium was not recovered from the factory, warehouse, solution filtrate, or unopened solution bottles; production of implicated lots was not clustered in time. Among 39 isolates tested, at least 10 different Fusarium species were identified, comprising 19 unique multilocus genotypes., Conclusions: The findings from this investigation indicate that this outbreak of Fusarium keratitis was associated with use of ReNu with MoistureLoc contact lens solution. Contact lens users should not use ReNu with MoistureLoc.
- Published
- 2006
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.