Search

Your search keyword '"Smyrlis, Athanasios"' showing total 11 results
Start Over Author "Smyrlis, Athanasios"
11 results on '"Smyrlis, Athanasios"'

4. A Complicated Case of Triple Valve Infective Endocarditis in an IV Drug User with a Bicuspid Aortic Valve Requiring Three Separate Salvage Operations: A Case Report and Literature Review

Author

Khan, Shahzad, Smyrlis, Athanasios, Yaranov, Dmitry, Oelberg, David, and Jimenez, Eric

Subjects
Article Subject, cardiovascular system, cardiovascular diseases
Abstract

Infective endocarditis (IE) is an infection of the endocardium that involves valves and adjacent mural endocardium or a septal defect. Local complications include severe valvular insufficiency, which may lead to intractable congestive heart failure and myocardial abscesses. If left untreated, IE is generally fatal. Diagnosing IE can be straightforward in patients with the typical oslerian manifestations such as bacteremia, evidence of active valvulitis, peripheral emboli, and immunologic vascular phenomena. In the acute course, however, the classic peripheral stigmata may be few or absent, particularly among intravenous drug abuse (IVDA) patients in whom IE is often due to a S. aureus infection of right-sided heart valves. We present a complicated case of a very aggressive native aortic valve MSSA (methicillin sensitive Staphylococcus aureus) IE in a young adult male with a past medical history of bicuspid aortic valve and IV drug abuse. His clinical course was complicated by aortic valve destruction and development of third-degree AV block, as well as an aorto-left atrial fistula requiring emergent operation for AV replacement and patch repair. The patient required two reoperations for recurrent endocarditis and its complications.

Published
2015
Full Text
View/download PDF

7. Inhibition of Renin Angiotensin Axis May Be Associated with Reduced Risk of Developing Venous Thromboembolism in Patients with Atherosclerotic Disease

Author

Chae, Young Kwang, primary, Khemasuwan, Danai, additional, Dimou, Anastasios, additional, Neagu, Stefan, additional, Chebrolu, Lakshmi, additional, Gupta, Shikha, additional, Carpio, Alejandra, additional, Kim, Jongoh, additional, Yun, Jeong Hyun, additional, Smyrlis, Athanasios, additional, Friedman, Alan, additional, and Tester, William, additional

Published
2014
Full Text
View/download PDF

10. Association between Common Allergic Symptoms and Cancer in the NHANES III Female Cohort.

Author

Young Kwang Chae, Neagu, Stefan, Jongoh Kim, Smyrlis, Athanasios, Gooptu, Mahasweta, Tester, William, and Yang, Isaac

Subjects
CANCER research, CANCER in women, BREAST cancer research, RHINITIS, CONJUNCTIVITIS
Abstract

Background: Previous epidemiological studies have investigated the association between allergic symptoms and cancer occurrence. However, the role of allergy in cancer has been elusive, especially for the female population. Methods: We examined the relationship between cancer prevalence and common allergic symptoms of rhinoconjunctivitis (RC) and wheezing (WZ) among NHANES III female participants. Results: Among 4600 people, 36.3% (n = 1669) did not have any allergic symptoms (NO), while 47.6% (n = 2188) reported RC, and 16.2% (n = 743), WZ. The proportion of cancer among NO groups was 5.43% (91/1669), among RC group, 7.63% (167/2188), and among WZ group, 11.23% (83/743) (RC group- OR 1.44 with 95% Cl 1.00-2.08; p = 0.05 while for WZ group- OR 2.20 with 95%Cl 1.27-3.80; p = 0.01). After adjusting for all the possible confounding variables including age, smoking, or COPD, having symptoms of RC (AOR 1.49 with 95%Cl 1.12-2.36; p = 0.01) or WC (AOR 2.08 with 95%Cl 1.11-3.89; p = 0.02) demonstrated consistent strong association with cancer. Among nonsmokers (n = 2505, 54.5%) only symptoms of RC showed association with cancer (AOR 1.51 with 95%Cl 1.00-2.28; p = 0.05). Among former or current smokers (n = 2094, 45.5%), only symptoms of WZ demonstrated association with cancer (AOR 2.38 with 95%Cl 1.16-4.87; p = 0.02). Among different types of cancers, odds of having breast cancer among participants with symptoms of RC or WZ were approximately twice the odds of having breast cancer among participants without any of these symptoms. AOR for RC group was 1.89 with 95%Cl 1.04-3.42 and p = 0.04 while AOR for WC group was 2.08 with 95%Cl 0.90-4.78 and p = 0.08. Conclusions: In summary, we found associations between common allergic symptoms like rhinitis/conjunctivitis and wheezing and prevalence of cancer, specifically between rhinitis/conjunctivitis and breast cancer that were not found in previous studies. Larger prospective studies are required to validate our findings. [ABSTRACT FROM AUTHOR]

Published
2012
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results