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Objectives: To determine if the association between posttraumatic stress disorder (PTSD) and substance use (alcohol misuse or smoking tobacco) is mediated/moderated by exercise or volunteering among aging (≥40 years) men who have sex with men (MSM), and if this mediation/moderation differs by HIV serostatus. Methods: Multicenter AIDS Cohort Study data were used. Three datasets with PTSD measured during different time periods (10/1/2017-3/31/2018, 898 men; 4/1/2018-9/30/2018, 890 men; 10/1/2018-3/31/2019, 895 men) were analyzed. Longitudinal mediation analyses estimated the mediation effect of exercise and volunteering on the outcomes. Results: Nine percent of MSM had evidence of PTSD. There was no statistically significant mediation effect of exercise or volunteering regardless of substance use outcome. The odds of smoking at a future visit among MSM with PTSD were approximately double those of MSM without PTSD. Results did not differ by HIV serostatus. Discussion: There is a particular need for effective smoking cessation interventions for aging MSM with PTSD. [ABSTRACT FROM AUTHOR]

INTRODUCTION: Tobacco claims over 8 million lives, with over 80% of the 1.3 billion users residing in low- and middle-income nations. India ranks highest in the proportion of users globally, notably in the Northeastern states. This paper aims to analyze the overall trends of smoking and smokeless tobacco (SLT) in the Northeast Region (NER) of India between the two rounds of the Global Adult Tobacco Survey (GATS) while analyzing the factors influencing tobacco used in the context of the region. MATERIALS AND METHODS: Descriptive analysis, estimation, and comparison of the prevalence of smoking and SLT were conducted for both rounds of GATS. The Chi-square test was employed to examine the association between variables such as gender, age, residence, education level, occupation, marital status, and caste while adjusting for GATS weight. RESULTS: The prevalence of smoking tobacco in GATS-II in NER is 19.3%, a decrease of 12% from GATS-I. While the use of manufactured cigarettes decreased by 33.7%, the use of bidi smoking and rolled tobacco in paper/leaf increased by 15.9% and 9.2%, respectively. The prevalence of SLT in GATS-II was 40.5%, a significant increase of 17% from GATS-I. While both genders exhibited increased tobacco usage, females experienced a particularly significant rise (18%) between the two survey rounds. No formal schooling, gender, rural residence, older age group, and occupation were significant factors in influencing the increased use of SLT. CONCLUSION: The prevalence of SLT consumption in the NER is on the rise, even as overall trends indicate a decrease in smoking tobacco. To effectively address this issue, tobacco should be integrated as a crosscutting concern across all levels of health programs. Multisectoral collaborations involving communities and schools can achieve regulatory and meaningful reductions in tobacco use.

Introduction: All service personnel are expected to be psychologically and physically healthy. However, certain behaviours may impede the above, and tobacco smoking is one out of many. Studies reiterate the high prevalence of smoking in the military, and the military culture, low education, younger age, psychiatric conditions childhood adversities, and alcohol and substance use are implicated. Methodology: This was a retrospective cross-sectional study, done in the Army Security Force Headquarters East, in a sample of 147 Officers and 3519 Other Ranks (ORs), serving > 2 years. A self-administered questionnaire inquired into demographic data, probable depression, high-risk drinking, symptoms of PTSD, symptoms of fatigue, cannabis use, childhood adversities, aggression, and cohesion. Smoking experience was assessed in terms of never, past and current use. The adjusted Odds Ratio determined the significance of the correlates of smoking. Results: Fifty point nine percent (95% CI 49.4% - 52.6%) were current smokers and 62.4% (95% CI 60.8%-64.0%) smoked in the past. Younger age, lower education, marriage, longer service, cannabis use and high-risk drinking were significantly associated with current and past smoking behaviours. Discussion: Compared to community surveys, smoking is high within the Army. Younger age, lower education, and lower rank were demographic covariates, which could be due to the inability to cope with stress and the military environment (i.e. due to the availability and the social influence). Alcohol and cannabis complement the effects of smoking. Depression and fatigue could be outcomes or causes of smoking. Health education and stress management programmes and imposing smoking restrictions within military installations are recommended to dissuade smoking in the Army.

Tobacco quitline services offer telephone-based counseling to assist tobacco users in quitting through behavioral modification. It is a sponsored scheme by the Ministry of Health and Family Welfare, Government of India. The present study has two objectives: primarily, to study the correlation between socio-demographic variables and tobacco abuse, and secondly, to study the impact of National Tobacco Quit-Line Services (NTQLS) in India. The data for the study was collected from the registered callers who have completed at least one year of follow-ups at NTQLS, Vallabhbhai Patel Chest Institute, University of Delhi, between May 2016 and May 2021. The questionnaire was directly administered to the people who had called NTQLS for the first time to quit tobacco use. Callers were provided one year of continuous follow-up to ensure they remain long-term abstinent from tobacco and permanently quit. All the data were managed through an electronic database. A total of 85,807 individuals’ data was taken for the study. The maximum number of callers were from Uttar Pradesh (28.03%), followed by Rajasthan (24.67%) and Madhya Pradesh (7.59%). The female population represented only 1.43%; the male population was significantly higher (98.57%). Youth (44.83%) and adults (53.78%) were more than seniors (0.9%) and adolescents (0.4%). Smokeless tobacco users (67.32%) were more common than smoking tobacco users (20.11%). Duration of tobacco use among the 71.74% of callers was found to be between 1 and 10 years; the remaining 24.03% had been using tobacco for over 10 years, while 4.23% were novice users. The abstinence rate achieved by NTQLS was 33.42% after one month of quitting and 21.91% after one year of quitting. We found a significant association between tobacco users’ socioeconomic and demographic status. The number of male tobacco users was significantly higher than the number of female tobacco users. Among all the tobacco users, youth was persistently using tobacco the most. Individuals from low socio-economic status were more likely to use tobacco as compared to those from high socioeconomic status. These associations indicate the need for strengthening the enforcement of tobacco control policies and developing and monitoring comprehensive smoke-free legislation.

Introduction: In today’s world, we know how important it is to keep healthy habits because many diseases begin with daily lifestyle choices. Dry eye disease is a disease of the ocular surface and there are many risk factors, that lead to developing this disorder. As the possible factors we can underline deficiency of vitamin D or Omega-3 fatty acids, lack of physical exercise, long screen time, or smoking tobacco. Aim of the study: This review seeks to highlight the issue of dry eye disease linked to everyday routines by examining clinical trial outcomes. Furthermore, it offers an analysis of potential strategies to prevent ocular alterations by critically evaluating the existing data. State of knowledge: The listed lifestyle choices cause a higher risk of developing dry eye disease and affect ocular health on many levels, leading to unpleasant feelings and affecting people’s lives. However, with some lifestyle changes, the risk of developing this disease can be decreased, and negative symptoms can be minimized. It is important to remember vitamin D, and Omega-3 supplementation, daily physical activity, minimalization of the time spent in front of the visual display terminals, and quitting smoking. Conclusions: Many daily habits are connected to developing dry eye disease, and it is very important to remember about the small daily changes, which can decrease the risk of the disease.

BackgroundTobacco usage is a major global public health concern, contributing to millions of deaths annually. This study focuses on security guards, an occupational group facing unique challenges, to investigate tobacco prevalence, usage patterns, and associated oral health risks.MethodsA cross-sectional study was conducted among security guards at a Tertiary Health Care Centre, from October 2022 to February 2023. Data on demographics, tobacco habits, and comorbidities were collected via a structured questionnaire. Clinical oral examinations provisionally diagnosed Oral Potentially Malignant Disorders (OPMDs) based on clinical findings. Appropriate Statistical analyses were employed.ResultsAmong 696 security guards, 40.1% used tobacco, including 15.0% smokers and 74.5% engaging in smokeless tobacco. Additionally, 10.3% reported using both smoking and smokeless forms. Non-tobacco users accounted for 59.9%. Tobacco users showed a higher prevalence of OPMDs (11.4%) compared to non-tobacco users (1.4%).DiscussionSecurity guards demonstrated a higher tobacco prevalence, with smokeless tobacco being predominant. Gender disparities in tobacco use emphasize the need for gender-specific interventions. The study highlights the significant impact of tobacco on oral health, especially the risk of OPMDs.ConclusionA high prevalence of tobacco usage (40.1%), particularly smokeless tobacco, among security guards, emphasizes the importance of targeted interventions within this occupational group. Oral Potentially Malignant Disorders (OPMDs) were significantly more prevalent (11.4%) in tobacco users. The association between tobacco usage and OPMDs reaffirms the well-established association between tobacco and adverse oral health outcomes.

Abstract Background Electronic cigarettes, or e-cigarettes, are devices that deliver nicotine-containing aerosol and were used by 2.8% of American adults in 2017. Many people who smoke cigarettes have used e-cigarettes for smoking cessation, and the general consensus among health providers is that while vaping is not harmless, it is less harmful than smoking. To try to reduce youth e-cigarette use, the Commonwealth of Massachusetts imposed a 75% excise tax on nicotine-containing vaping products and banned the sale of all flavored tobacco products, including combustible tobacco, effective June 1, 2020. This tax, like similar taxes in other states, aimed to reduce e-cigarette consumption. However, past research has found that e-cigarettes and cigarettes are economic substitutes, meaning that an increase in e-cigarettes prices may push more people who smoke e-cigarettes to smoke combustible cigarettes. Methods To determine the impacts of several events, such as the e-cigarette and vaping-associated lung injury (EVALI) outbreak and implementation of the Massachusetts e-cigarette tax, on e-cigarette and cigarette purchasing, we conducted an interrupted time-series analysis of year-on-year consumer purchasing data to impute changes in e-cigarette and cigarette purchasing in the Greater Boston area and the entire USA after several intervention points. We then surveyed a subset of people who used e-cigarettes to evaluate the plausibility that some e-cigarette consumers would travel out-of-state to purchase e-cigarettes. Results The purchasing data indicated that there was no significant decrease in e-cigarette purchases in the Greater Boston convenience market after tax implementation. However, we found that e-cigarette purchases decreased significantly while cigarette purchases increased after several bans on e-cigarettes and numerous policy statements related to the EVALI outbreak. The survey results suggested that people who smoke e-cigarettes did not decrease their consumption after the implementation of the tax, but instead obtained e-cigarettes outside of Massachusetts. Conclusion These results suggest that the Massachusetts flavor ban and tax did not reduce e-cigarette consumption in the Greater Boston area, and that messaging questioning the safety of e-cigarettes led to an increase in combustible cigarette use. This suggests the need for health authorities to reconsider how they communicate the relative risks of smoking and vaping.

Laser-induced breakdown spectroscopy (LIBS), a laser-based atomic spectroscopic technique, has been used to investigate the presence of toxic/heavy elements/compounds in various smoking tobacco samples. Based on the analysis of the LIBS spectra, the presence of toxic elements like Cr, Sb, Sr, Ni, and Ba, including organic elements C, H, N, O and other common elements like Fe, Mg, Na, and K, has been confirmed in the tobacco samples. Electronic bands of diatomic molecules such as CN and C2 are also observed in the LIBS spectra of the samples, which may be due to the presence of nicotine, chlorophyll, anthocyanin, etc., organic compounds. Calibration-free LIBS (CF-LIBS), a mathematical method, is used to determine the concentration of constituents using the intensity of the spectral lines of the species in the tobacco samples. Atomic absorption spectroscopy (AAS) technique is also used to determine the concentration of elements. The result obtained by AAS validates the result obtained using the CF-LIBS method. The presence of the organic compounds/molecules in the tobacco samples has been investigated using photoacoustic spectroscopy (PAS). Based on the analysis of the PAS spectrum, various organic compounds/molecules like nicotine, chlorophyll, pheophytin, β-carotenoid, anthocyanin, pheophytin, chlorophyllide, and bacteriochlorophy II are identified in the tobacco samples. UV-Visible absorption spectroscopy of these samples is used to compare the results obtained by PAS. Principal component analysis, a multivariate method, is applied to LIBS data to classify the various smoking tobacco samples based on their constituents. Our results show that ten smoking tobacco samples of different brands are forming three different clusters based on the similarity of their constituents. [ABSTRACT FROM AUTHOR]

Objectives: The present study was conducted to examine the prevalence of tobacco smoking among students' of different departments of private medical science college at Dammam, as well as to assess students' attitude, practice, knowledge, and awareness towards smoking and its harmful effects. Materials and Methods: A cross-sectional study was performed at Mohammed Al-Mana College for Medical Sciences (MACHS) in February 2020. Data were obtained through adopted pretested validated questionnaire based on the Global Adult Tobacco Survey. The questionnaire contains demographic details, smoking behavior, knowledge, and behavior attitude toward smoking. Results: A total of 388 students completed the questionnaire out of them 108 males (27.8%) and 280 females (76.2%), the prevalence ratio of tobacco use 19.84%. The prevalence ratio of female current smokers was 7.9%, whereas male 11.8%, even though the number of female participants were high. Female students had better knowledge in comparison with male students regarding the harmful effects of tobacco smoking on health (78.7% vs. 82.8%; P ≤ 0.001), and as a risk factor of brain thrombosis (59.2% vs. 60%; P ≤ 0.001), gastric ulcer (55.5% vs. 62.1%; P ≤ 0.001), asthma (62.9% vs. 72.1%; P ≤ 0.001), and lung cancer (81.4% vs. 86.7%; P ≤ 0.001). Conclusion: The prevalence of smoking tobacco was relatively low among MACHS students who had good general knowledge regarding the harmful effects of smoking tobacco. This study results showed the harmful effects of smoking and can be used as a basis for the development of tobacco education programs at MACHS and any other institution for providing professional support for students to quit smoking.

Background: Tobacco is one of the most important preventable causes of death and a leading public health problem all over the world. The present study was conducted to determine the effect of community-based intervention for tobacco cessation in urban slums of Ahmedabad city. Materials and Methods: A total of 20 slums (10 slums each) in the intervention and control group were randomly selected through the process of randomization. A total of 200 participants each in the intervention and control group were studied through a cluster-randomized trial. Results: The outcome of the community-based tobacco intervention measured after 6 months depicted that the odds ratio (OR) of the prevalence of tobacco abstinence, quit rate, and reduction of more than 50% of tobacco use was significantly higher (30.37 times, 2.84 times, and 2.19 times respectively more) in the intervention as compared to the control group. However, after 1 year of the first and immediately after the second intervention, the OR of tobacco point prevalence abstinence, quit rate, and reduction of more than 50% was more pronounced (5.11 times, 3.52 times, and 4.31 times, respectively, more) in the intervention group than the control group. Post intervention, it was also observed that there was a significant increase in the average quit attempt. Conclusion: The community-based intervention was very effective in reducing the consumption of tobacco in urban slums in any form. As per the study findings, there is a wide possibility for the integration of tobacco cessation activity into the health program.

Introduction: Tobacco consumption is one of the most leading causes of preventable deaths around the world. According to the World Health Organisation (WHO), eight million deaths occur annually due to tobacco usage. Aim: To identify the prevalence of oral lesions among people who use tobacco, their knowledge on health hazards of tobacco uses and the dependence on nicotine among adults in the age group between 18 and 60 years. Materials and Methods: A community-based, cross-sectional study was conducted in Department of Community Medicine, Christian Medical College, Vellore, Tamil Nadu, India, among an urban community of Vellore, January 2019 and June 2019. This study included 930 participants. An interviewer administrated questionnaire was used to assess the prevalence of tobacco and dependence on nicotine among adults. The participants who use tobacco were examined for oral lesions. Univariate analysis was performed to highlight the variables of this study and logistic regression model was used to find the adjusted odds ratios and p-values. Results: The total number of adults who participated in this study was 930. The median age group among the study population was 38 years and the mean age was 38.26±12 years. About two-third (62.2%) of the participants were females. The proportion of adults currently using tobacco in any form was 24.19% (n=225) with those Smoking Tobacco (ST) was 59.1% (n=133), Smokeless Tobacco (SLT) was 38.6% (n=87) and using both ST and SLT were 2.2% (n=5). The prevalence of oral mucosal lesions was found to be 60.1% with smoker's palate (N=96) being the most frequently occurring oral mucosal lesion. The nicotine dependence was found to be significant in the subjects with age more than 45 years and had used tobacco for more than 20 years. On the analysis of the knowledge on health hazards, it was identified that 76.3% of the participants were aware that use of tobacco in any form can cause oral lesions. Conclusion: This study highlights that oral lesions and nicotine dependence are highly prevalent among the tobacco users. This emphasises the need for community-based oral health awareness programs highlighting the consequences of tobacco usage in order to prevent the incidence of oral cancers. [ABSTRACT FROM AUTHOR]

Introduction The burden of tobacco use is high in India. Tobacco use behaviour is influenced by sociodemographic factors. The Indian state of Kerala is considered unique compared to the rest of India in having high social development indices. The objective of this study was to explore the sociodemographic factors affecting tobacco use and its predictors in Kerala. Methods A cross-sectional study was conducted using data obtained from the Global Adult Tobacco Survey 2 (2016-2017) for the state of Kerala in India. Questions from the survey pertaining to sociodemographic characteristics (age, gender, area of residence, marital status, religion, education level, and employment status) were selected and served as independent variables. Outcomes are reported as odds ratios. Results A total of 2186 individuals (783 men and 1403 women) participated in GATS-2 of Kerala state. People aged

Background: Tobacco cessation interventions provided in a dental office or hospital settings are beneficial in helping patients to quit tobacco. Regular monitoring of these interventions is required to assess their success rate and factors hindering its improvement. This study evaluated cessation services provided through a Tobacco Cessation Clinic (TCC) established in a government teaching dental hospital in Delhi, India. Materials and Methods: Patients visiting the TCC from April 2016 to March 2018 were contacted to participate in this study. All the willing participants were administered a structured questionnaire telephonically or in person. The questionnaire focused on gathering information on patients' current tobacco use status, feedback on intervention provided at TCC and reasons for missing TCC appointments. Bivariate and multivariate analysis was performed to assess the effect of socio-demographic factors, nicotine dependence and interventions at TCC on current tobacco use status of participants. Results: Of the 309 participants, 60 (19.4%) reported complete tobacco abstinence and 78 (22.3%) reduced consumption by more than half from their first visit to TCC. Most of the participants (81.5%) were satisfied with the tobacco cessation interventions provided at the TCC. Multivariate analysis shows that odds of quitting were higher in participants with low tobacco dependence (OR 3.03, CI 0.98,9.35) and those who were satisfied with counselling method at TCC (OR 8.8, CI 2.05, 38.35). Conclusion: Interventions provided at our TCC were found beneficial by the study participants to reduce tobacco consumption or achieve total tobacco abstinence. A timely reminder can be provided to increase patients' compliance.

Introduction: The relationship of tobacco use to dental caries is still unclear. The aim of this study is to assess the relationship between smoking and smokeless tobacco usage and prevalence of dental caries and its pattern in the Varanasi population. Materials and Methods: In this study, 472 elderly dentate and consenting individuals were included. Individuals were examined with the aid of mouth mirror, No. 23 explorer, and cotton rolls. The age of the study group ranged from 16 years to 75 years. Individuals were categorized as smoking tobacco users, smokeless tobacco users, and the combination of these two. Frequency and dosage of tobacco usage was recorded. Dental caries was measured using decayed, missing, and filled teeth (DMFT) index. Oral hygiene practices such as mode, material, and frequency of brushing were also recorded. Data were assessed using SPSS 17.0 using Chi-square, t-test, ANOVA test, and binary regression. Results: Caries rate was similar in both males and females (2.57 and 2.70), and the difference was not statistically significant. Caries was higher in individuals with habits when compared to those who were not having habits. There was no statistically significant association between individuals who were smokers, using smokeless tobacco, frequency, mode, and material of brushing with caries pattern. Among smokers, DMFT increased with frequency and duration of smoking, and it was statistically significant; however, in smokeless tobacco users, this was not the case. There was a positive correlation with DMFT and frequency of smoking. Conclusion: The study has shown that tobacco habit is a risk factor for increased caries activity, and it is higher in smokers as compared to smokeless tobacco chewers.

Introduction: Tobacco consumption is one of the most leading causes of preventable deaths around the world. According to the World Health Organisation (WHO), eight million deaths occur annually due to tobacco usage. Aim: To identify the prevalence of oral lesions among people who use tobacco, their knowledge on health hazards of tobacco use and the dependence on nicotine among adults in the age group between 18 to 60 years. Materials and Methods: A community-based, cross-sectional study was conducted in Department of Community Medicine, Christian Medical College, Vellore, Tamil Nadu, India, among an urban community of Vellore, between January 2019 to June 2019. This study included 930 participants. An interviewer administrated questionnaire was used to assess the prevalence of tobacco and dependence on nicotine among adults. The participants who use tobacco were examined for oral lesions. Univariate analysis was performed to highlight the variables and logistic regression model was used to find the adjusted odds ratios and p-values . A p-value

Introduction: E-cigarettes, also known as electronic cigarettes or vape pens, are battery-powered devices that deliver nicotine, flavorings, and other chemicals to users in the form of an aerosol. It revolutionized the landscape of nicotine consumption, marketed as a safer alternative to traditional cigarettes. Since then, e-cigarettes have become popular among young adults and adolescents. There has always been a conflict in the risks versus benefits of e-cigarettes over the decade, which has created a gap in knowledge in the population. This study aimed to attain the knowledge, attitude, and practice of students from a semi-urban background to understand the level of education needed among the young population of our country., Methods: This online survey was conducted among 411 students of Shri BM Patil Medical College Hospital and Research Centre (BLDE) (DU), College, Vijayapura, Karnataka. The survey consisted of 21 MCQ questionnaires to assess students' knowledge, attitude, and practice toward e-cigarettes. Later, the data was analyzed using SPSS version 28., Results: The study included a diverse group of 411 participants, with a majority being males (63%) and the rest females (37%). The age distribution highlighted a young demographic, with 93% of participants aged between 18 and 34. The study revealed a high level of awareness about e-cigarettes, with 90% of participants being familiar with them. Friends and social media emerged as the primary sources of information, accounting for 52% and 40%, respectively. While 48% of the participants believed e-cigarettes to be non-addictive, only 19% recognized their addictive potential, with the rest being unsure. A majority, 45%, did not see e-cigarette users as superior to traditional smokers, while 15.5% held the opposite view. While 58% of e-cigarette users found them to be stress-relieving, 33% did not, highlighting a subjective aspect of e-cigarette use., Conclusion: The study offers critical insights into the knowledge, attitudes, and practices regarding e-cigarettes among medical students in northern Karnataka. While awareness is high, there is a notable gap in accurate understanding of e-cigarettes' safety and addictive nature. The findings emphasize the need for enhanced education and awareness campaigns to correct misconceptions about e-cigarettes., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Ethics Committee of Shri BM Patil Medical College Hospital and Research Centre issued approval 025/2023-24. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Ashok et al.)

Clear renal cell carcinoma (RCC) is the most common primary renal tumor originating within the renal cortex. It is responsible for 75% to 85% of all primary renal neoplasms. Multiple risk factors are associated with the development of RCC, the most common being smoking. On some occasions, RCC has been linked to some autoimmune conditions, but data is limited. Especially, its association with glomerulonephritis (GN) is rare in literature and not fully understood. In this case report, we discuss a presentation of RCC associated with crescentic GN., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Sharieh et al.)

Background Developing communities like Iraq are critical to building a good community environment. Many complex patterns of behaviors like smoking among adolescents have been exacerbated rapidly in the current era which led to changes in the Iraqi community's perspectives and life expectancy. This study aims to find out the prevalence of smoking among secondary school students in Iraq and their perceived contributing factors. Methods A cross-sectional study design was used with a representative sample of Iraqi school students recruited through a multistage cluster randomization from the Nineveh Governorate's intermediate and secondary schools to ensure the representation of the general public strata. A total of 330 students were randomly selected from eight schools distributed all over Mosul city (the center of Nineveh Governorate) and its boundaries semi-rural areas. Data collection utilized a standardized, anonymous questionnaire based on the Global Youth Tobacco Survey (GYTS) administered within classrooms with the researcher's presence. The questionnaire included questions related to sociodemographic characteristics of the students, smoking state, smoking types, frequency of smoking, relative smoking state, opinion on predisposing factors for initiation of smoking, and knowledge about hazards of smoking. Data analysis was done using SPSS version 26 to calculate frequency distribution with further logistic regression analysis was performed to identify statistically significant factors contributing to initiation of smoking among the student participants with p-value estimation of any compares considered significant below 0.05. Results Prevenance of all types of smoking was 24.5% from 330 students with 30% from 246 males and 7% from 84 females has been encountered. Hookah (Shisha) was the most prevalent type of smoking. About a third of the smoker sample reported smoking at least once daily. Peer pressure (OR=3.49, P< 0.001) or family smoking (OR=1.769, P=0.019) emerged as the strongest influence for initiation of smoking, besides stress (OR=2.23, P= 0.04) and personality traits like stammering and jealousy (OR=2.58, P= 0.013), (OR=2.22, P= 0.017, respectively) have also significant odds. Interestingly, media (movie star) influence played a significant role also. (OR=1.492, P= 0.045). Conclusion The prevalence of smoking among the study sample was 24.5 % out of 330 participating students. Significant influencing factors were found that raised the concern and necessitated the development of targeted interventions. Implementing evidence-based strategies, such as comprehensive school-based educational programs and smoke-free indoor air policies, can significantly improve public health outcomes., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Medical Research Ethics Committee (MREC) issued approval UOM/COM/MREC/22-23(43). Protocol title: Prevalence of Smoking among School Students in Iraq. We are pleased to inform you that the Medical Research Ethics Committee, College of Medicine, University of Mosul has reviewed your research documents and has approved in principle your protocol. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Zubair et al.)

Background: Tobacco usage is a major global public health concern, contributing to millions of deaths annually. This study focuses on security guards, an occupational group facing unique challenges, to investigate tobacco prevalence, usage patterns, and associated oral health risks., Methods: A cross-sectional study was conducted among security guards at a Tertiary Health Care Centre, from October 2022 to February 2023. Data on demographics, tobacco habits, and comorbidities were collected via a structured questionnaire. Clinical oral examinations provisionally diagnosed Oral Potentially Malignant Disorders (OPMDs) based on clinical findings. Appropriate Statistical analyses were employed., Results: Among 696 security guards, 40.1% used tobacco, including 15.0% smokers and 74.5% engaging in smokeless tobacco. Additionally, 10.3% reported using both smoking and smokeless forms. Non-tobacco users accounted for 59.9%. Tobacco users showed a higher prevalence of OPMDs (11.4%) compared to non-tobacco users (1.4%)., Discussion: Security guards demonstrated a higher tobacco prevalence, with smokeless tobacco being predominant. Gender disparities in tobacco use emphasize the need for gender-specific interventions. The study highlights the significant impact of tobacco on oral health, especially the risk of OPMDs., Conclusion: A high prevalence of tobacco usage (40.1%), particularly smokeless tobacco, among security guards, emphasizes the importance of targeted interventions within this occupational group. Oral Potentially Malignant Disorders (OPMDs) were significantly more prevalent (11.4%) in tobacco users. The association between tobacco usage and OPMDs reaffirms the well-established association between tobacco and adverse oral health outcomes., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (© 2024 Chauhan, Paul, Bhadauria, Purohit, Duggal, Barma, Agarwal, Bhukal, Sasidharan, Shukla, Khan, Shenoy, Malhotra and Priya.)

Background: Tobacco is one of the most important preventable causes of death and a leading public health problem all over the world. The present study was conducted to determine the effect of community-based intervention for tobacco cessation in urban slums of Ahmedabad city. Materials and Methods: A total of 20 slums (10 slums each) in the intervention and control group were randomly selected through the process of randomization. A total of 200 participants each in the intervention and control group were studied through a cluster-randomized trial. Results: The outcome of the community-based tobacco intervention measured after 6 months depicted that the odds ratio (OR) of the prevalence of tobacco abstinence, quit rate, and reduction of more than 50% of tobacco use was significantly higher (30.37 times, 2.84 times, and 2.19 times respectively more) in the intervention as compared to the control group. However, after 1 year of the first and immediately after the second intervention, the OR of tobacco point prevalence abstinence, quit rate, and reduction of more than 50% was more pronounced (5.11 times, 3.52 times, and 4.31 times, respectively, more) in the intervention group than the control group. Post intervention, it was also observed that there was a significant increase in the average quit attempt. Conclusion: The community-based intervention was very effective in reducing the consumption of tobacco in urban slums in any form. As per the study findings, there is a wide possibility for the integration of tobacco cessation activity into the health program [ABSTRACT FROM AUTHOR]

Background: It is ascertained that the survival rate of patients infected with type 16 human papillomavirus (HPV16) positive is better as compared to those infected with HPV16 negative. The present study was conducted to determine rgw role of HPV16 and risk factors in assessing oropharyngeal cancer (OPC) death. Methodology: A total of 102 clinically and histologically proven cases of oral pharyngeal cancer were included. Seropositivity for HPV16 E6 as a marker of HPV16-positive cancer was estimated. Results: Out of 102 patients, there were 70 males and 32 females. Significant risk factors associated with OPC survival overall in the univariate analysis was female sex (hazard ratio [HR] 0.54, 95% confidence level [CL]: 0.36–80), alcohol use >2 drinks/day (HR 1.54, 95% CL: 1.12–2.08), smoking >10 pack-years (HR 2.20, 95% CL: 1.42–3.58), moderate dental (HR 1.54, 95% CL: 1.02–2.32), underweight (HR 2.24, 95% CL: 1.34–3.60), and Stage IV cancer (HR 2.82, 95% CL: 1.76–4.40). There was significant low risk for death among HPV16 positive (HR 0.48, 95% CL: 0.32–0.70). Conclusion: HPV16 status is an independent prognostic factor for OPC deaths. The common risk factors were female gender, moderate oral care, underweight body mass index, excessive alcohol, and smoking tobacco.

Objectives: The present study was conducted to examine the prevalence of tobacco smoking among students' of different departments of private medical science college at Dammam, as well as to assess students' attitude, practice, knowledge, and awareness towards smoking and its harmful effects. Materials and Methods: A cross-sectional study was performed at Mohammed Al-Mana College for Medical Sciences (MACHS) in February 2020. Data were obtained through adopted pretested validated questionnaire based on the Global Adult Tobacco Survey. The questionnaire contains demographic details, smoking behavior, knowledge, and behavior attitude toward smoking. Results: A total of 388 students completed the questionnaire out of them 108 males (27.8%) and 280 females (76.2%), the prevalence ratio of tobacco use 19.84%. The prevalence ratio of female current smokers was 7.9%, whereas male 11.8%, even though the number of female participants were high. Female students had better knowledge in comparison with male students regarding the harmful effects of tobacco smoking on health (78.7% vs. 82.8%; P = 0.001), and as a risk factor of brain thrombosis (59.2% vs. 60%; P = 0.001), gastric ulcer (55.5% vs. 62.1%; P = 0.001), asthma (62.9% vs. 72.1%; P = 0.001), and lung cancer (81.4% vs. 86.7%; P = 0.001). Conclusion: The prevalence of smoking tobacco was relatively low among MACHS students who had good general knowledge regarding the harmful effects of smoking tobacco. This study results showed the harmful effects of smoking and can be used as a basis for the development of tobacco education programs at MACHS and any other institution for providing professional support for students to quit smoking. [ABSTRACT FROM AUTHOR]

The outcome of the osseointegrated implant is influenced by various conditions, one of which is smoking. Literature shows conflicting results for the association between smoking and implant success. Hence, the study was conducted to assess the effects of smoking on survival and marginal bone loss of osseointegrated implants. Literature search of published articles in Medline, Scopus, Ovid, and Journal of Web till June 2020 were analyzed for the determined outcomes. Revman 5.4 software was used for the analysis of the study. Of the 437 articles screened, nine were chosen for review and analysis. Meta-analytic results showed that implant success rate was better in nonsmokers than smokers (odds ratio = 0.43, 95% confidence interval = 0.26–0.72, P < 0.0001). Smoking habit does seem to affect the implant outcome of survival and marginal bone loss negatively. [ABSTRACT FROM AUTHOR]

Background: Gastric cancer is one of the main causes of cancer related deaths particularly in northern parts of Iran. It has been recently attributed to the increased application of agricultural pesticides in these areas. CYP1A1 is the prototype member of the cytochrome P450 detoxifying enzymes that its gene expression alterations as a result of genetic or epigenetic changes, has been verified to have significant role on gastric cancer incidence. Materials and Methods: In this cross-sectional study, genomic DNA of tumoral and normal stomach tissues was extracted by phenol chloroform protocol and was subjected to bisulfite conversion by the EpiTech DNA Bisulfite kit. CpG-rich regions of the CYP1A1 gene promoter was amplified using specific primers and subsequently was sequenced in both directions using direct bisulfite Sanger sequencing method. Methylation rate of the individual CpGs was calculated and its correlation with demographic features was estimated by Spearman's test. Results: Results showed a significant positive correlation between promoter methylation of the CYP1A1 gene, particularly those CpGs existing in Xenobiotic response elements (XRE) consensus sequence, and smoking habit as well as familial history of gastric cancer. However, increasing age showed no significant effect on the methylation rate of the CYP1A1 gene promoter. Conclusion: Smoking and familial history of gastric cancer showed positive correlation with CYP1A1 gene promoter methylation. Screening of the CYP1A1 gene promoter methylation in smokers and individuals having positive familial history of disease may be used as a marker for gastric cancer diagnosis.

Introduction. As for operational purposes concerning risk factors and activities in health promotion of the National Health Program, one should find the point of talking about reducing the prevalence of smoking. The main characteristics of tobacco dependence are: inability to stop smoking or significantly reducing it, the emergence of withdrawal syndrome caused by smoking cessation, persistent intake of tobacco, even when serious illness should prompt discontinuation. Aim. The aim of the research conducted among the students of Lublin universities was to identify the level of nicotine use by young people, to find out socio-demographic components of these behaviours and to determine the need for preventive activities in the field of cigarette smoking Meterial and methods. Studies were carried out among full-time students of all the public universities in Lublin: the Medical University (MU), the Maria Curie-Skłodowska University (MCSU), University of Life Sciences (ULS), the John Paul II Catholic University of Lublin (CUL), Technical University of Lublin (TUL). Results.The study shows that 75% of students do not smoke cigarettes at all, while among smokers – 12% smoke regularly and 13% occasionally. We noticed a very interesting relationship - it turned out that women smoke more than men and are more likely to declare regular smoking. Also interesting is the fact that people living while studying in the family home and having parents with higher education smoke more. Conclusions.Nicotine smoking is a serious problem among students of Lublin universities.

Background: Electronic cigarettes, or e-cigarettes, are devices that deliver nicotine-containing aerosol and were used by 2.8% of American adults in 2017. Many people who smoke cigarettes have used e-cigarettes for smoking cessation, and the general consensus among health providers is that while vaping is not harmless, it is less harmful than smoking. To try to reduce youth e-cigarette use, the Commonwealth of Massachusetts imposed a 75% excise tax on nicotine-containing vaping products and banned the sale of all flavored tobacco products, including combustible tobacco, effective June 1, 2020. This tax, like similar taxes in other states, aimed to reduce e-cigarette consumption. However, past research has found that e-cigarettes and cigarettes are economic substitutes, meaning that an increase in e-cigarettes prices may push more people who smoke e-cigarettes to smoke combustible cigarettes. Methods: To determine the impacts of several events, such as the e-cigarette and vaping-associated lung injury (EVALI) outbreak and implementation of the Massachusetts e-cigarette tax, on e-cigarette and cigarette purchasing, we conducted an interrupted time-series analysis of year-on-year consumer purchasing data to impute changes in e-cigarette and cigarette purchasing in the Greater Boston area and the entire USA after several intervention points. We then surveyed a subset of people who used e-cigarettes to evaluate the plausibility that some e-cigarette consumers would travel out-of-state to purchase e-cigarettes. Results: The purchasing data indicated that there was no significant decrease in e-cigarette purchases in the Greater Boston convenience market after tax implementation. However, we found that e-cigarette purchases decreased significantly while cigarette purchases increased after several bans on e-cigarettes and numerous policy statements related to the EVALI outbreak. The survey results suggested that people who smoke e-cigarettes did not decrease their consumption after the implementation of the tax, but instead obtained e-cigarettes outside of Massachusetts. Conclusion: These results suggest that the Massachusetts flavor ban and tax did not reduce e-cigarette consumption in the Greater Boston area, and that messaging questioning the safety of e-cigarettes led to an increase in combustible cigarette use. This suggests the need for health authorities to reconsider how they communicate the relative risks of smoking and vaping. [ABSTRACT FROM AUTHOR]

Background/aims Most countries have gone through lockdowns to varying degrees during the COVID-19 pandemic to reduce the spread of the disease. The successive pandemic waves have impacted the health system, imposing restrictions set by the government. This changed people's daily life routines and they felt more socially isolated, which in turn had an impact on their mental health. Some factors were linked to the severity and outcome of COVID-19 on patients. One of these factors was smoking. This study was carried out to investigate the prevalence and impact of lockdown on smoking habits, as well as the changes in attitudes, behavior, and the rate of consumption before and after the government restrictions in the general population of Saudi Arabia. Materials and methods The present cross-sectional study was conducted on a sample of 921 participants from the general population of Saudi Arabia. Data were collected via an online questionnaire. A structured self-response questionnaire was given to the participants after institutional research ethical approval was obtained for the study. Results A total of 921 participants from the smoker population of Saudi Arabia were included in the study. The majority of participants were male (72.9%), and more than half were aged between 18 and 34 years (53.7%). Single individuals had a higher prevalence of increased smoking and a lower rate of quitting compared to married individuals. Participants with higher education levels were more likely to continue smoking at the same rate. While 40.5% of participants reported no change in their smoking rate during the pandemic, 15.4% reported a decrease, 39.0% reported an increase, and 5.1% reported quitting smoking. Participants who reported feeling more stressed during the pandemic had a higher prevalence of increased smoking. The majority of participants believed that smoking increased the risk of COVID-19 infection. Conclusion The study highlights the need for targeted smoking cessation interventions and support services during the pandemic, considering demographic factors, living arrangements, and psychological impact. Efforts should be made to raise awareness about the negative health consequences of smoking during the pandemic and provide resources for stress management and alternative coping strategies. These findings have important implications for public health interventions and policies in Saudi Arabia., Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Research Ethics Committee, Imam Mohammad Ibn Saud Islamic University (IMSIU) issued approval 339/2022. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work., (Copyright © 2024, Alhazani et al.)

Introduction Tobacco products contain heavy metals and polycyclic aromatic hydrocarbons (PAHs) that can be released during burning. The aim of this study was to measure the concentrations in tobacco of the heavy metals: Lead (Pb), Cadmium (Cd), Chrome (Cr), and Zinc (Zn); and the amount polycyclic aromatic hydrocarbons (PAHs) in tobacco and tobacco product emissions using Cambridge filter pads under U.S. Federal Trade Commission (FTC) standard conditions. Methods In the present analytical study, samples of 25 tobacco brands of different origin were analyzed to determine both heavy metal concentrations utilizing flame atomic absorption spectroscopy (FAAS) and polycyclic aromatic hydrocarbons amounts using gas chromatography (GC). Results The average concentrations of Pb, Cd, Cr and Zn s were 4.56, 0.39, 3.31 and 1.36 μg/g, respectively. The amount of PAHs in cigarette emissions ranged from 474.17 ng/ cigarette to 1060.87 ng/cigarette for tobacco brands labelled C13 and C2, respectively. The order in amount of the PAHs in the smoke of the study tobacco brands was: nap > flu > acpy > phn > fln > pyr > acp > ant > chr > bap > bbf (full names listed in main text). Conclusions Tobacco and tobacco product emissions contain significant concentrations of heavy metals and PAHs amounts, respectively.

As a result of the conducted studies the dependence of the quality indicators of consumer tobacco on duration and storage conditions was determined.

Orofacial clefts (OFCs) are among the most common birth defects and impart a significant burden on afflicted individuals and their families. It is increasingly understood that many nonsyndromic OFCs are a consequence of extrinsic factors, genetic susceptibilities, and interactions of the two. Therefore, understanding the environmental mechanisms of OFCs is important in the prevention of future cases. This review examines the molecular mechanisms associated with environmental factors that either protect against or increase the risk of OFCs. We focus on essential metabolic pathways, environmental signaling mechanisms, detoxification pathways, behavioral risk factors, and biological hazards that may disrupt orofacial development. [ABSTRACT FROM AUTHOR]

Background: Tobacco cessation interventions provided in a dental office or hospital settings are beneficial in helping patients to quit tobacco. Regular monitoring of these interventions is required to assess their success rate and factors hindering its improvement. This study evaluated cessation services provided through a Tobacco Cessation Clinic (TCC) established in a government teaching dental hospital in Delhi, India.. Materials and Methods: Patients visiting the TCC from April 2016 to March 2018 were contacted to participate in this study. All the willing participants were administered a structured questionnaire telephonically or in person. The questionnaire focused on gathering information on patients' current tobacco use status, feedback on intervention provided at TCC and reasons for missing TCC appointments. Bivariate and multivariate analysis was performed to assess the effect of socio-demographic factors, nicotine dependence and interventions at TCC on current tobacco use status of participants.Results: Of the 309 participants, 60 (19.4%) reported complete tobacco abstinence and 78 (22.3%) reduced consumption by more than half from their first visit to TCC. Most of the participants (81.5%) were satisfied with the tobacco cessation interventions provided at the TCC. Multivariate analysis shows that odds of quitting were higher in participants with low tobacco dependence (OR 3.03, CI 0.98,9.35) and those who were satisfied with counselling method at TCC (OR 8.8, CI 2.05, 38.35).Conclusion: Interventions provided at our TCC were found beneficial by the study participants to reduce tobacco consumption or achieve total tobacco abstinence. A timely reminder can be provided to increase patients' compliance. [ABSTRACT FROM AUTHOR]

INTRODUCTION Tobacco products contain heavy metals and polycyclic aromatic hydrocarbons (PAHs) that can be released during burning. The aim of this study was to measure the concentrations in tobacco of the heavy metals: Lead (Pb), Cadmium (Cd), Chrome (Cr), and Zinc (Zn); and the amount polycyclic aromatic hydrocarbons (PAHs) in tobacco and tobacco product emissions using Cambridge filter pads under U.S. Federal Trade Commission (FTC) standard conditions. METHODS In the present analytical study, samples of 25 tobacco brands of different origin were analyzed to determine both heavy metal concentrations utilizing flame atomic absorption spectroscopy (FAAS) and polycyclic aromatic hydrocarbons amounts using gas chromatography (GC). RESULTS The average concentrations of Pb, Cd, Cr and Zn s were 4.56, 0.39, 3.31 and 1.36 µg/g, respectively. The amount of PAHs in cigarette emissions ranged from 474.17 ng/cigarette to 1060.87 ng/cigarette for tobacco brands labelled C13 and C2, respectively. The order in amount of the PAHs in the smoke of the study tobacco brands was: nap > flu > acpy > phn > fln > pyr > acp > ant > chr > bap > bbf (full names listed in main text). CONCLUSIONS Tobacco and tobacco product emissions contain significant concentrations of heavy metals and PAHs amounts, respectively. [ABSTRACT FROM AUTHOR]

Introduction: The relationship of tobacco use to dental caries is still unclear. The aim of this study is to assess the relationship between smoking and smokeless tobacco usage and prevalence of dental caries and its pattern in the Varanasi population. Materials and Methods: In this study, 472 elderly dentate and consenting individuals were included. Individuals were examined with the aid of mouth mirror, No. 23 explorer, and cotton rolls. The age of the study group ranged from 16 years to 75 years. Individuals were categorized as smoking tobacco users, smokeless tobacco users, and the combination of these two. Frequency and dosage of tobacco usage was recorded. Dental caries was measured using decayed, missing, and filled teeth (DMFT) index. Oral hygiene practices such as mode, material, and frequency of brushing were also recorded. Data were assessed using SPSS 17.0 using Chi-square, t-test, ANOVA test, and binary regression. Results: Caries rate was similar in both males and females (2.57 and 2.70), and the difference was not statistically significant. Caries was higher in individuals with habits when compared to those who were not having habits. There was no statistically significant association between individuals who were smokers, using smokeless tobacco, frequency, mode, and material of brushing with caries pattern. Among smokers, DMFT increased with frequency and duration of smoking, and it was statistically significant; however, in smokeless tobacco users, this was not the case. There was a positive correlation with DMFT and frequency of smoking. Conclusion: The study has shown that tobacco habit is a risk factor for increased caries activity, and it is higher in smokers as compared to smokeless tobacco chewers. [ABSTRACT FROM AUTHOR]

Background: It is ascertained that the survival rate of patients infected with type 16 human papillomavirus (HPV16) positive is better as compared to those infected with HPV16 negative. The present study was conducted to determine rgw role of HPV16 and risk factors in assessing oropharyngeal cancer (OPC) death. Methodology: A total of 102 clinically and histologically proven cases of oral pharyngeal cancer were included. Seropositivity for HPV16 E6 as a marker of HPV16-positive cancer was estimated. Results: Out of 102 patients, there were 70 males and 32 females. Significant risk factors associated with OPC survival overall in the univariate analysis was female sex (hazard ratio [HR] 0.54, 95% confidence level [CL]: 0.36–80), alcohol use >2 drinks/day (HR 1.54, 95% CL: 1.12–2.08), smoking >10 pack-years (HR 2.20, 95% CL: 1.42–3.58), moderate dental (HR 1.54, 95% CL: 1.02–2.32), underweight (HR 2.24, 95% CL: 1.34–3.60), and Stage IV cancer (HR 2.82, 95% CL: 1.76–4.40). There was significant low risk for death among HPV16 positive (HR 0.48, 95% CL: 0.32–0.70). Conclusion: HPV16 status is an independent prognostic factor for OPC deaths. The common risk factors were female gender, moderate oral care, underweight body mass index, excessive alcohol, and smoking tobacco. [ABSTRACT FROM AUTHOR]

The emergence of the epidemic of nicotine addiction in India and other nations is a global public health tragedy of untoward proportions. Smoking or chewing tobacco can seriously affect general, as well as oral health. Smoking-caused disease is a consequence of exposure to toxins in tobacco smoke and addiction to nicotine is the proximate cause of these diseases. This article focuses on nicotine as a determinant of addiction to tobacco and the pharmacologic effects of nicotine that sustain cigarette smoking. The pharmacologic reasons for nicotine use are an enhancement of mood, either directly or through relief of withdrawal symptoms and augmentation of mental or physical functions. Tobacco cessation is necessary to reduce morbidity and mortality related to tobacco use. Strategies for tobacco cessation involves 5A's and 5R's approach and pharmacotherapy. Dental professionals play an important role in helping patients to quit tobacco at the community and national levels, to promote tobacco prevention and control nicotine addiction. Dentists are in a unique position to educate and motivate patients concerning the hazards of tobacco to their oral and systemic health, and to provide intervention programs as a part of routine patient care.

Aim: To assess the prevalence of tobacco-related oral habits (TROH) in Mahabubnagar district of Telangana, India. Materials and Methods: A cross-sectional study was conducted among 3200 participants in Mahabubnagar district of Telangana, India. People aged 16–75 years and both men and women in same proportions were included in the study. Data was obtained by interviewing individual participants regarding various TROH. Results: Out of 3200 participants, 750 (23.44%) had TROH, whereas 2450 (76.56%) did not have any tobacco habits. In 750 participants who had TROH, the habit of tobacco chewing was more common (44.5%) followed by the habit of smoking (42.7%) and both smoking and chewing (12.8%). Conclusion: From the present study, we can conclude that prevalence of TROH is alarmingly high in this district. Oral physicians have an important role in tobacco control as they can directly see the harmful effects of tobacco in the mouth.

Introduction:  Tobacco smoking remains a health concern, especially in developing countries. Nicotine is significantly linked to many cancers and even second-hand exposure. Hence, smoking can increase the risk of lung and heart disease. This makes quitting smoking important and challenging. Success tends to rise by achieving abstinence with assisted pharmacology. These treatments aim to reduce symptoms of nicotine withdrawal. This is a preclinical trial on glutamate modulator in N-acetylcysteine (NAC) as a new potential treatment for smoking cessation. It is based on the administration of NAC related to elevated levels of dopamine in the central nervous system to accomplish successful smoking cessation., Aim: This study evaluated the efficacy and tolerability of NAC for smoking cessation. The primary outcome was abstinence rate and the secondary outcomes of the study were to assess carbon monoxide exhalation value (CO exh ), the withdrawal symptoms, craving score, safety, and tolerability associated with the administration of NAC., Methods: This is a randomized clinical trial. Eligible smokers were treated with NAC 2400 mg twice daily (BID) or placebo to obtain a potential effective abstinence rate. Subjects recruited from the smoking cessation clinic were screened for eligibility and were randomized to either the NAC or placebo group. The trial consisted of a four-week treatment phase and participants were evaluated each week with a brief counseling. Intention to treat data analysis was performed from 2018 to 2019. Smoking cessation status was verified by measuring the amount of carbon monoxide exhaled and by documenting their smoking habits. Adverse events (AEs) have also been observed on each visit., Results: A total of 90 male smokers with a mean (SD) age of 38.7 (11) years were randomized into two groups to receive NAC (n=45) and placebo (n=45). The primary outcome revealed that the abstinence rate was significantly higher for the NAC group than the placebo group (37.7% vs 6.6%; p=0.02). These findings were supported by data comparison between the NAC group and placebo group of CO exh (ppm) (9.59 ±7.4 vs 13,4 ±6.1; p=0.04) and cigarette consumption/week (10 vs 46; p <0.001), which were statistically significant. Comparison of withdrawal with the Minnesota Nicotine Withdrawal Score between the NAC group and the placebo group showed lower values (8 (1-31) vs 11 (0-43); p=0.178), respectively, even though not statistically significant. Compared to the placebo group, the craving score (6 (2-29) vs 12 (6-31); p=0.04) in the NAC group was significantly lower. The most common adverse event was mild gastrointestinal effects (28.9%) and arthralgia (2.2%). No serious adverse events were detected., Conclusions:  Despite a small sample size, the data demonstrate the potential benefits of NAC that may help elevate abstinence rates and promote successful smoking cessation pharmacotherapy. Comprehensive treatment combining pharmacologic therapy and counseling increases smoking cessation success rates. It is essential to conduct a randomized multicenter study with a large population to support a sustained abstinence rate using NAC., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2024, Harlivasari et al.)

This retrospective cohort study examines the association between male smoking status and embryo development in vitro. The study included non-smoking women aged under 40 years who underwent in vitro fertilization (IVF) at Yanaihara Women's Clinic from May 2019 to May 2022, and they were divided into two groups according to the husband's smoking status. The effect of male smoking status on IVF outcomes was compared retrospectively based on embryonic development using a time-lapse incubator. A total of 184 patients were included; 272 oocytes of 45 female non-smokers were cultured with the sperm of male smokers, and 816 oocytes of 139 female non-smokers were cultured with the sperm of male non-smokers. No significant differences were observed between male smokers and non-smokers groups with regard to fertilization and the top-quality embryo on day 3 and day 5 (p > 0.05). The male smoker group's embryos reached the early cleavage-stage parameters (time of pronuclei appearance to the five-cell stage) significantly earlier than the male non-smoker group's embryos (p < 0.05). However, no significant differences were observed between the two groups in other parameters of top-quality blastocysts (p > 0.05). It was concluded that male smoking has some differences on the timing of early embryonic events on time-lapse examination., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2024, Taniguchi et al.)

Waterpipe tobacco smoking, commonly known as hookah or shisha, has witnessed a surge in popularity globally, particularly among young adults. However, this activity is associated with several issues related to health. This comprehensive narrative review aims to provide a valuable resource for researchers, policymakers, and public health professionals seeking to deepen their understanding of waterpipe tobacco smoking and implement evidence-based strategies to address its challenges. The present article focuses on an in-depth analysis of the health risks associated with waterpipe tobacco smoking. Based on evidence from the current scientific literature, the review explores the impact of waterpipe smoking on respiratory health, cardiovascular outcomes, and the potential links to infectious diseases. Additionally, the review discusses the emerging evidence on the long-term health consequences, highlighting the need for continued research in this area. Also, it touches on the regulatory challenges surrounding waterpipe tobacco smoking, which were critically examined, emphasizing the gaps and inconsistencies in existing policies. Finally, the review underscores the public health imperatives necessitated by the rise of waterpipe tobacco smoking. The narrative concludes by proposing a holistic approach that integrates scientific evidence, regulatory frameworks, and public health initiatives to mitigate the growing impact of waterpipe tobacco smoking on population health., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2024, Yadav et al.)

Background: Smoking tobacco during pregnancy can lead to adverse pregnancy and child health outcomes. Aim: To gain insight of smoking during pregnancy from young pregnant women's lived experience. Method: A descriptive phenomenological approach was used. Semi-structured interviews were conducted with five women aged 18-20 years who had smoked tobacco during pregnancy. Findings: Themes that emerged from the data were related to culture and routine, psychological wellbeing, self-efficacy, public opinion, recognition of harm, whom they spoke to about smoking, and the approaches that helped behaviour change. Conclusions: Midwives were seen as the trusted health professional by the young women and a non-judgemental approach was valued to promote self-efficacy. Smoking cessation services were not recognised as beneficial, and cutting down, rather than using nicotine replacement therapy or e-cigarettes, was preferred. [ABSTRACT FROM AUTHOR]

Objectives: More and more countries introduce a total ban on smoking tobacco in public places. The aim of this work was to evaluate the effectiveness of “The Act of 8 April 2010 on amendment of the act on protection of health against the consequences of consumption of tobacco and tobacco products and act on National Sanitary Inspectorate” and assess the frequency of complying with the smoking bans by the students of the Medical University of Lodz, Poland. Material and Methods: Between 2007–2011, at the Social Medicine Institute of the Medical University of Lodz, a study using random survey was carried out involving students who were starting their studies at the Health Department of the Medical University of Lodz. The analysis of the collected material showed that 1038 people reported being smokers at the time of the study. Among that group, 530 students were included in the study prior to, and 508 after the introduction of the amendment. In order to verify their compliance with the smoking ban, the respondents were asked whether they smoked only in designated areas or wherever they wanted to. Results: The ratio of people claiming they smoked anywhere they wanted to, disregarding the smoking ban, was 60% (N = 318) and after the amendment had been introduced, this ratio was 62.2% (N = 316), it increased by 2.2 percentage points. The observed difference was statistically irrelevant (Chi2 = 0.530, p > 0.05). Conclusions: The Act ”On amendment of the act on protection of health against the consequences of consumption of tobacco and tobacco products and Act on National Sanitary Inspectorate” in Poland did not result in the expected changes in the frequency of complying with the smoking ban by the 1st year students.