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2. Safety and efficacy of intraperitoneal drain placement after emergency colorectal surgery: An international, prospective cohort study
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Sgro, A, Blanco-Colino, R, Ahmed, W, Brindl, N, Gujjuri, R, Lapolla, P, Mills, E, Perez-Ajates, S, Soares, A, Varghese, C, Xu, W, Mclean, K, Chapman, S, Espin-Basany, E, Glasbey, J, Mihaljevic, A, Nepogodiev, D, Pata, F, Pellino, G, Pockney, P, Dudi-Venkata, N, Egoroff, N, Ludbrook, I, Raubenheimer, K, Richards, T, Delibegovic, S, Salibasic, M, Amjad, T, Dorr-Harim, C, Gedeon, N, Gsenger, J, Tachezy, M, Bini, S, Gallo, G, Gori, A, Picciariello, A, Podda, M, Riboni, C, Machatschek, M, Nguyen, A, Jakubauskas, M, Kryzauskas, M, Poskus, T, Kuiper, S, Wang, J, Wells, C, Bissett, I, Augestad, K, Steinholt, I, Vieira, B, Juloski, J, Anabitarte Bautista, O, Kasmy El Kasmy, Y, Martin-Borregon, P, Ossola Revilla, M, Van Straten, S, Aktas, M, Baki, B, Akhbari, M, Baker, D, Bhatia, S, Brown, S, Cambridge, W, Kamarajah, S, Khaw, R, Kouli, O, Murray, V, Trout, I, Yasin, I, Wong, J, Reyhani, H, Wong, K, Pancharatnam, R, Chia, W, Walmsley, A, Hassane, A, Saeed, D, Wang, B, Walters, B, Nowinka, Z, Alsaif, A, Mirza, M, Foster, K, Luu, J, Kakodkar, P, Hughes, J, Yogarajah, T, Antypas, A, Rahman, A, Bradbury, M, Mclarnon, M, Nagi, S, Riad, A, Erotocritou, M, Kyriacou, H, Kaminskaite, V, Alfadhel, S, Fatimah Hussain, Q, Handa, A, Massy-Westropp, C, Custovic, S, Dimov, R, Mughal, H, Slavchev, M, Ivanov, T, Gouvas, N, Hegazi, A, Kocian, P, Kjaer, M, Mark-Christensen, A, Papakonstantinou, D, Machairas, N, Triantafyllou, T, Garoufalia, Z, Korkolis, D, Castaldi, A, Giaccari, S, Spolverato, G, Pagano, G, Milone, M, Turri, G, Colombo, F, Cucinotta, E, Poillucci, G, Perra, T, Tutino, R, Belia, F, Coletta, D, Belli, A, Rega, D, Cianci, P, Pirozzolo, G, Di Lena, M, Perrone, F, Giani, A, Lovisetto, F, Grassia, M, Pipitone Federico, N, Ferrara, F, Biancafarina, A, Tamini, N, Sinibaldi, G, Tuminello, F, Galleano, R, Sasia, D, Bragaglia, L, de Manzoni Garberini, A, Pesce, A, Cassaro, F, Venturelli, P, Canu, G, Esposito, G, Campanelli, M, Cardia, R, Ricciardiello, M, Sagnotta, A, Canonico, G, De Marco, G, Cappiello, A, Pinotti, E, Carlei, F, Lisi, G, Bagaglini, G, Farrugia, M, Meima - van Praag, E, Monteiro, C, Pereira, M, Botelho, P, Quigley, A, O'Neill, A, Gaule, L, Crone, L, Arnold, A, Grama, F, Beuca, A, Tulina, I, Litvin, A, Panyko, A, Ossola, M, Trujillo Diaz, J, Marin Santos, J, Alonso Batanero, E, Gortazar de las Casas, S, Soldevila Verdeguer, C, Colas-Ruiz, E, Talal El-Abur, I, Garcia Dominguez, M, Delorme, M, Sauvain, M, Ozmen, B, Ozkan, B, Calikoglu, F, Kural, S, Zafer, F, Kaya, Y, Yalcinkaya, A, Kargici, K, Tepe, M, Tatar, O, Kabadayi, E, Yildirim, A, Hurmuzlu, D, Korkmaz, K, Sharma, P, Troller, R, Hagan, N, Mooney, J, Light, A, Tansey, M, Bhojwani, D, Mcging, R, Mallon, A, Fadel, M, Spilsbury, C, James, R, O'Brien, S, Isaac, A, Balasubramanya, S, Sadik, H, Gala, T, Chen, J, Turner, B, Goh, E, Hassan, K, Karam, M, Mason, P, Tzoumas, N, Noton, T, Seehra, J, Ahmed, N, Motiwale, R, Tanna, V, Argyriou, A, Bylapudi, S, Grace, N, Latif, S, Hounat, A, Kiam, J, Zaidi, M, Elsamani, K, Hughes, C, Suresh, A, Sinan, L, El-Dalil, D, Khoo, E, Salim, E, Stark, D, Minhas, N, Fowler, G, Rees, E, Giudiceandrea, I, Bardon, A, Jayawardena, P, Dieseru, N, Murphy, A, Yates, C, Ziolkowska, K, Rafie, A, Khoda, F, Okocha, M, Ashdown, T, Vitish-Sharma, P, Gilliland, J, Toh, S, Jones, K, Devine, A, Berry, A, Mcdonnell, S, Olivier, J, Richardson, G, Lim, H, Slim, N, Elsayeh, K, Sammour, T, Sarpanov, A, Belev, N, Dimitrov, D, Dusek, T, Ntomi, V, Sotiropoulos, G, Theodorou, D, Nikiteas, N, Balalis, D, Antropoli, C, Altomare, D, Luglio, G, De Palma, G, Pedrazzani, C, Simonelli, L, Brozzetti, S, Porcu, A, Massani, M, Grazi, G, Izzo, F, Delrio, P, Restini, E, Chetta, G, Lantone, G, Ferrari, G, Lucchi, A, De Prizio, M, Caristo, G, Borghi, F, Petrucciani, N, Huscher, C, Cocorullo, G, Tonini, V, Medas, F, Sica, G, Cillara, N, Anastasi, A, Bianco, F, Giuliani, A, Carlini, M, Selvaggi, F, Sammarco, G, Ozolins, A, Malasonoks, A, Andrejevic, P, Tanis, P, van de Ven, A, Gerhards, M, Ribeiro da Silva, B, Silva, A, Lima, M, Kavanagh, D, Mccawley, N, Bintintan, V, Karamarkovic, A, Sanz Ortega, G, De Andres-Asenjo, B, Nevado Garcia, C, Garcia Florez, L, Segura-Sampedro, J, Blas Laina, J, Ponchietti, L, Buchwald, P, Gialamas, E, Ozben, V, Rencuzogullari, A, Gecim, I, Altinel, Y, Isik, O, Yoldas, T, Isik, A, Leventoglu, S, Erturk, M, Guner, A, Guler, S, Attaallah, W, Ugur, M, Ozbalci, G, Marzook, H, Eardley, N, Smolarek, S, Morgan, R, Roxburgh, C, Lala, A, Salama, Y, Singh, B, Khanna, A, Evans, M, Shaikh, I, Maradi Thippeswamy, K, Appleton, B, Moug, S, Smith, I, Smart, N, Shah, P, Williams, G, Khera, G, Goede, A, Varcada, M, Parmar, C, Duff, S, Hargest, R, Marriott, P, Speake, D, Ben Sassi, A, Furfaro, B, Daudu, D, Golijanin, N, Yek, W, Capasso, G, Mansour, L, Niu, N, Seow, W, Hamidovic, A, Kulovic, E, Letic, E, Aljic, A, Helez, M, Banji-Kelan, A, Dimitrova, N, Kavradjieva, P, Ivanov, V, Jukaku, A, Hadzhiev, D, Gabarski, A, Karamanliev, M, Vladova, P, Iliev, S, Yotsov, T, Epsilonupsilonsigmataualphathetaiotaomicronupsilon, E, Vetsa, K, Stavrinidou, O, Papatheodorou, P, Liassides, T, Georgiou, T, Al Nassrallah, M, Altaf, R, Negametzyanov, M, Zagibova, D, Foltys, F, Stefanova, H, Paspala, A, Bompetsi, G, Sidiropoulos, T, Stamopoulos, P, Triantafyllou, A, Theodoropoulos, C, Kimpizi, A, Palyvou, T, Charalabopoulos, A, Syllaios, A, Schizas, D, Liatsou, E, Baili, E, Vagios, I, Tomara, N, Davakis, S, Palumbo, A, Foroni, F, Dibra, R, Papagni, V, Urbani, A, Rossin, E, Nezi, G, Romano, P, Amendola, A, Esposito, E, Manigrasso, M, Anoldo, P, Vertaldi, S, Gecchele, G, Sabrina, Z, Guerci, C, Cammarata, F, Lamperti, G, Zaffaroni, G, Benuzzi, L, Ferrario, L, Cigognini, M, Mazzeo, C, Badessi, G, Pintabona, G, Fassari, A, Mingoli, A, Cirillo, B, D'Alterio, C, Brachini, G, Tancredi, M, Zambon, M, Aulicino, M, Sapienza, P, Liberatore, P, Scanu, A, Feo, C, Iacomino, A, Pelizzo, P, Rossi, S, Vigna, S, Grossi, U, Grillo, V, Agnes, A, Schena, C, Marincola, G, Oddi, A, Perotti, B, Mario, V, Perri, P, Zazza, S, Aversano, A, Scala, D, Di Lauro, K, Leongito, M, Piccirillo, M, Patrone, R, Capuzzolo, S, Vignotto, C, Bao, Q, Giuseppe, C, Angarano, E, Marino, F, Pezzolla, F, Gigante, G, Magistro, C, Crippa, J, Maspero, M, Carnevali, P, Trapani, R, Zonta, S, Agostinelli, L, Vittori, L, Romeo, L, Doria, E, Farnesi, F, Danna, R, Andolfi, E, Pellicano', G, Angelini, M, Scricciolo, M, Zanframundo, C, Ciulli, C, Ripamonti, L, Cigagna, L, Oldani, M, Larcinese, A, Rossi, D, Picone, E, Crescentini, G, Marano, A, Migliore, M, Giuffrida, M, Palagi, S, Testa, V, Borrello, A, Lucarini, A, Garofalo, E, Canali, G, Orlandi, P, Nervegna, F, Marchegiani, F, Damoli, I, Licata, A, Trovato, C, Alicata, F, Sardo, F, Milazzo, M, Randisi, B, Dominici, D, Sartarelli, L, Zanni, M, Pisanu, A, Soddu, C, Delogu, D, Erdas, E, Campus, F, Cappellacci, F, Casti, F, Marcialis, J, Atzeni, J, Sensi, B, Franceschilli, M, Bellato, V, Cannavera, A, Putzu, G, di Mola, F, Picardi, B, Solinas, L, Loponte, M, Rossi del Monte, S, Di Martino, C, Linari, C, Spagni, G, Capezzuoli, L, Tirloni, L, Nelli, T, Caridi, A, Elter, C, Camassa, M, D'Amico, S, Bargellini, T, Incollingo, P, Montuori, M, Maffione, F, Romano, L, Valiyeva, S, Spoletini, D, Menegon Tasselli, F, Sciaudone, G, Selvaggi, L, Menna, M, De Paola, G, Fulginiti, S, Truskovs, A, Weiss, C, Saknitis, G, Rauscher, J, Larnovskis, J, Jeyarajan-Davidsson, M, Nitisa, D, Gille, N, Reiser, S, Roshan, M, Leseman, C, van Dalen, A, Top, C, Detering, R, Matos, C, Silva, C, Pinto, D, Mendes, J, Couto, J, Leite, M, Velez, C, Damasio Cotovio, M, Cinza, A, Pedroso de Lima, R, Boyle, E, Yang, H, Banerjee, I, Rahmat, S, Afzal, Z, Reid, C, Dumitrascu, F, Croyle, J, Gressmann, K, Cullen, N, Graham, A, Nasehi, A, Montano King, C, Martin, B, Stokell, C, Sanderson, N, Farnan, R, Jassim, S, Chan, B, Chua Vi Long, K, Kaka, N, Pandey, S, Neo, W, Chitul, A, Bezede, C, Cincilei, D, David, A, Blaga, M, Blaga, S, Fagarasan, V, Khetagurova, M, Rodimov, S, Kapustina, A, Mekhralyzade, A, Zabiyaka, M, Jankovic, U, Cuk, V, Hajska, M, Dubovsky, M, Hrosova, M, Ferancikova, N, Camarero Rodriguez, E, Laguna Alcantara, F, Adarraga, J, Jezieniecki, C, Ruiz Soriano, M, Gomez Sanz, T, Suarez, A, Sanchez Garcia, C, Cifrian Canales, I, Llosa Perez, J, Merayo, M, Urbieta, A, Gegundez Simon, A, Tone, J, Gazo Martinez, J, Vicario Bravo, M, Chavarrias, N, Gil Catalan, A, Oseira, A, Villalonga, B, Jeri, S, Perez Calvo, J, Nogues, A, Cros, B, Yanez, C, Utrilla Fornals, A, Roldon Golet, M, Colsa, P, Gimenez Maurel, T, Axmarker, T, Chevallay, M, Pham, T, Sel, E, Atar, C, Aba, M, Sarkin, M, Akkaya, Y, Durmaz, A, Gullu, H, Boga, A, Aktas, A, Bakar, B, Demirel, M, Hysejni, X, Taser, M, Guzel, O, Bozbiyik, O, Ozen, D, Olmez, M, Uyar, B, Gulcek, E, Kayacan, G, Atici, N, Gul, O, Altiner, S, Ibis, B, Altunsu, S, Banaz, T, Diler, C, Demirbas, I, Usta, M, Erkul, O, Orman, R, Salih, S, Utkan, N, Acil, C, Ozgur, E, Maddahali, M, Turhan, A, Eskici, A, Ular, B, Dogru, M, Ozturk, O, Arslan, E, Panahi Sharif, A, Dikmen, E, Ates, J, Bircan, R, Cavus, T, Sever, A, Balak, B, Duman, E, Altay, L, Emanet, O, Cullen, F, Tan, J, Nathan, A, Rottenberg, A, Williams, C, Mitrofan, C, Xu, D, Bawa, J, Morris, P, Gordon, D, Richmond, G, Hui, J, Ighomereho, O, Rocks, R, Mccabe, S, Fitzpatrick, A, Nicoletti, J, Auterson, L, Darrah, N, Soh, V, Ong, C, Utukuri, M, Gallagher, C, Stuart, L, Hipolito, M, Douglas, N, Ghazal, R, Parris, G, Catchpole, J, Bryden, M, Jamal, S, Karim, Z, Lyon-Dean, C, Rowley, G, Lee, K, Whitehurst, O, Mirza, A, Sheikh, F, Yousaf, H, Bilbao, J, Sinclair, R, Takar, S, Kressel, H, Chan, V, Schack, K, Osborne, R, Baldemor, S, Smyth, S, Gilmour, S, Ting, A, Bozonelou, I, Saunders, P, Qhaireel Anwar, Q, Tirimanna, R, Jauhari, S, Gardener, A, Walker, B, Wenban, C, Reddy, H, Conway-Jones, R, Loganathan, S, Clynch, A, James, C, Matey, E, Cameron, F, Roberts, W, Gicquel, A, Milliken, C, Forbes, J, Rubinchik, P, Azmi, A, Hawkes, C, Cornett, L, Adarkwah, P, Mcconville, R, O'Hara, S, Tijare, C, Parkes, J, Yao, L, Ahmad, R, Shafiq, U, Mhaisalkar, A, Gurung, A, de Stadler, K, Elias, S, Thomas, T, Madras, A, Jani, A, Daler, H, Tong, K, Sundaralingam, S, Szal, A, Khan, A, O'Sullivan, C, Baker, E, Joseph-Gubral, J, Hadley, E, Trivedi, R, Igwelaezoh, E, Barton, H, Allison, W, Hurst, W, Alam, F, Parkes, I, Jamshaid, M, Azizan, N, Burgher, T, Afzal, A, Eltilib, I, Zahid, M, Sadiq, O, Lloyd, A, Ho, R, Brazukas, A, Li, C, Kamdar, M, Mohamed Nazeer, M, Mighiu, A, Kim, D, Wilkins, L, Kuo, L, Rafe, T, Maduka, D, Cheema, H, Farag, K, Abdellatif, M, Nzewi, R, Kruczynska, A, Grasselli, H, Yousuff, M, Bassi, R, Mann, A, Chopra, J, Shaikh, M, D Sa, S, Tsimplis, V, Ghanchi, A, Skene, E, Asim, K, Zaheer, M, Chan, S, Dalton, H, Gibbons, K, Adderley, O, Chukwujindu, I, Jayasuriya, I, Sivanu, K, Borumand, M, Chick, G, Bridges, I, Tomlin, J, Mckenna, J, Nandra, N, Grieco, C, Quek, F, Mercer, R, Brankin-Frisby, T, Sattar, A, Aslam, A, Edelsten, E, Shafi, S, Kouli, T, Ford, V, Gurung, F, Fernandes, M, Deader, N, Ponniah, R, Jamieson, S, Davies, A, Taubwurcel, J, Aung, M, Desai, R, Begum, S, Jamadar, T, Kangatharan, A, Rzeszowski, B, Ho, C, Yap, S, Prendergast, M, Sethi, R, Duku, A, Lowe, C, Bray, J, Ghobrial, M, Nichita, V, Wagstaff, A, Rengasamy, E, Abu Hassan, F, Mahmood, H, Savill, N, Shah, S, Almeida, T, Edwards, A, Catchpole, B, Halford, Z, Carmichael, A, Alsusa, H, Boyd, M, Williams, J, Feyi-Waboso, J, Patel, M, Zeidan, Z, Bailey, E, Bapty, J, Brazkiewicz, M, Tremlett, A, Pringle, H, Mankal, S, Chung, W, Parry-Jones, E, Anderson, K, Mcforrester, A, Stanley, A, Hoather, A, Wise, H, Laid, I, Scriven, J, Braniste, A, Wilson, A, Le Blevec, L, Pakunwanich, N, Evans, N, Chong, H, White, C, Hunter, J, Haque, M, Vanalia, P, Murdoch, S, Choudhary, T, Mccann, A, Harun, A, Shah, H, Hunt, S, Shafiq, Y, Bickley-Morris, E, Emms, L, Dare, M, Akula, Y, Deliyannis, E, Mayes, F, Ellacott, M, Zagorac, Z, Farren, A, Manning, C, Hughed, C, Stewart, E, Lim, K, Chohan, N, Thaker, A, Thompson, B, Ahari, D, Burdekin, E, Okwu, U, Akintunde, A, Lhaf, F, Douthwaite, J, Govindan, R, Leelamanthep, S, Gull, E, Wright, F, Dundas, L, Mackdermott, N, Burchi-Khairy, T, Campbell, I, Walsh, J, Yeo, J, Meehan, S, Banerjee, D, Fu, M, Kawka, M, Ali, T, Hussain, Z, Thomas, C, Ahmad, H, Moroney, J, Yick, C, Risquet, R, Ntuiabane, D, Shimato, M, Khan, M, Ilangovan, S, Vaselli, N, Smithers, R, Uhanowita Marage, R, Valnarov-Boulter, A, Kayran, J, Banerjee, M, Parekh-Hill, N, Hooper, A, Bowen, J, Jagdish, R, Mcquoid, C, Khan, N, O Hare, R, Jeffery, S, Zahid, A, Elsworth, C, Walter, L, Dhillon, S, Rao, S, Anthony, A, Ashaye, A, Phillips, N, Faderani, R, Pengelly, S, Choi, S, Kwak, S, Lau, Y, Bagheri, K, Ong, D, Kerr, E, Falconer, K, Clancy, N, Douglas, S, Zhang, Y, Greenfield, F, Mutanga, I, Mcalinden, J, Willis, L, Adefolaju, A, Agarwal, H, Barter, R, Harris, G, Spencer, G, Lee, M, V Vadiveloo, T, Herbert, G, Patel, R, Shah, M, El Falaha, S, Wong, C, Soare, C, Akram, J, Bozhkova, L, Ma, Y, Vo, U, Tan, H, Leto, L, Kamal, M, Hadzhieva, E, Krastev, P, Tonchev, P, Kokkinos, G, Pozotou, I, Sabbagh, D, Votava, J, St, F, Koliakos, N, Tsaparas, P, Zografos, G, Mantas, D, Tsourouflis, G, Fradelos, E, Trigiante, G, Labellarte, G, Resta, G, Capelli, G, D'Amore, A, Verlingieri, V, Campagnaro, T, Maffioli, A, Viscosi, F, De Lucia, C, Meneghini, S, Fancellu, A, Colella, M, Biondi, A, De Peppo, V, Pace, U, Albino, V, Gattulli, D, Piangerelli, A, Kalivaci, D, Sisto, G, Mazzola, M, Caneparo, A, Lunghi, E, Nespoli, L, Angrisani, M, Langone, A, Gelarda, E, Virgilio, E, Angelini, E, Fornasier, C, Asero, S, Filippone, E, Frongia, F, Calo, P, Panaccio, P, Ipponi, P, Gili, S, Braccio, B, Tiesi, V, Stolcers, K, Kokaine, L, Novikovs, V, Capel, L, Bastiaenen, V, Heijmans, H, Henriques, S, Gan, S, Ramanayake, H, Nolan, M, Temperley, H, Ciofic, E, Pop, B, Kurtenkov, M, Jovanovic, M, Vician, M, Egea Arias, P, Beltran de Heredia, J, Labalde Martinez, M, De Santiago Alvarez, I, Alvarez-Gallego, M, Rodriguez Artigas, J, Dwidar, O, Korkmaz, H, Eray, I, Meric, S, Aydin, R, Cetin, B, Karaca, B, Kuyumcu, O, Yuksel, E, Uprak, T, Karabulut, K, Kavukcu, E, Mansor, A, Hackett, R, Zammit-Maempel, M, Sabaratnam, R, Maan, A, Ferarrio, I, Dixon, L, Halai, H, Sethi, S, Nelson, L, Grassam-rowe, A, Krishnan, E, Deeny, D, Mckeever, M, George Pandeth, A, Dhavala, P, Sreenivasan, S, Sundaram Venkatesan, G, Zhu, L, Atiyah, Z, Gregory, J, Morey, T, Seymour, Z, Holdsworth, L, Abdelmahmoud, S, Bourhill, J, Bisheet, G, Shaw, J, Kulkarni, K, Kumarakulasingam, P, Pillay, S, Al-Habsi, R, Kungwengwe, G, Richards, J, Davoudi, K, Ibrahim, B, Tailor, B, Zayed, M, Chen, F, Bailey, S, Sheefat, S, Nawaz, G, Pawar, R, Marsh, S, Sam, Z, Roy Bentley, S, Simpson, C, Lim, Y, Ooi, R, Toh, W, Mannion, P, Lovett, A, Kincius, A, Hussein, S, Kirby, E, Beckett, R, Salmon, J, Glynn, T, Choo, S, Lyons, S, Browne, D, Ravindran, W, Ahmad, S, Zhu, X, Mcnulty, J, Mccarthy, L, Ng, J, Karmally, Z, Mcteir, K, Hanna, M, Tan, E, Namdeo, S, Schembri, R, Pusey, E, Sgro A., Blanco-Colino R., Ahmed W. U. R., Brindl N., Gujjuri R. R., Lapolla P., Mills E. C., Perez-Ajates S., Soares A. S., Varghese C., Xu W., McLean K. A., Chapman S. J., Espin-Basany E., Glasbey J. C., Mihaljevic A., Nepogodiev D., Pata F., Pellino G., Pockney P., Dudi-Venkata N. N., Egoroff N., Ludbrook I., Raubenheimer K., Richards T., Delibegovic S., Salibasic M., Amjad T., Dorr-Harim C., Gedeon N., Gsenger J., Tachezy M., Bini S., Gallo G., Gori A., Picciariello A., Podda M., Riboni C., Machatschek M. J., Nguyen A., Jakubauskas M., Kryzauskas M., Poskus T., Kuiper S. Z., Wang J., Wells C. I., Bissett I. P., Augestad K. M., Steinholt I., Vieira B. N., Juloski J., Anabitarte Bautista O., Kasmy El Kasmy Y., Martin-Borregon P., Ossola Revilla M., Van Straten S., Aktas M. K., Baki B. E., Akhbari M., Baker D., Bhatia S., Brown S., Cambridge W., Kamarajah S. K., Khaw R. A., Kouli O., Murray V., Trout I., Yasin I., Wong J. Y., Reyhani H., Wong K. H. F., Pancharatnam R., Chia W. L., Walmsley A., Hassane A., Saeed D., Wang B., Walters B., Nowinka Z., Alsaif A., Mirza M., Foster K., Luu J., Kakodkar P., Hughes J. T., Yogarajah T., Antypas A., Rahman A., Bradbury M., McLarnon M., Nagi S., Riad A. M., Erotocritou M., Kyriacou H., Kaminskaite V., Alfadhel S., Fatimah Hussain Q., Handa A., Massy-Westropp C., Custovic S., Dimov R., Mughal H., Slavchev M., Ivanov T., Gouvas N., Hegazi A., Kocian P., Kjaer M. D., Mark-Christensen A., Papakonstantinou D., Machairas N., Triantafyllou T., Garoufalia Z., Korkolis D., Castaldi A., Giaccari S., Spolverato G., Pagano G., Milone M., Turri G., Colombo F., Cucinotta E., Poillucci G., Perra T., Tutino R., Belia F., Coletta D., Belli A., Rega D., Cianci P., Pirozzolo G., Di Lena M., Perrone F., Giani A., Lovisetto F., Grassia M., Pipitone Federico N. S., Ferrara F., Biancafarina A., Tamini N., Sinibaldi G., Tuminello F., Galleano R., Sasia D., Bragaglia L., de Manzoni Garberini A., Pesce A., Cassaro F., Venturelli P., Canu G. 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T., Desai R., Begum S., Jamadar T., Kangatharan A., Rzeszowski B., Ho C., Yap S. H. K., Prendergast M., Sethi R., Duku A., Lowe C., Bray J., Ghobrial M., Nichita V., Wagstaff A., Rengasamy E., Abu Hassan F., Mahmood H., Savill N., Shah S., Almeida T., Edwards A., Catchpole B., Halford Z., Carmichael A., Alsusa H., Boyd M., Williams J., Feyi-Waboso J., Patel M., Zeidan Z., Bailey E., Bapty J., Brazkiewicz M., Tremlett A., Pringle H., Mankal S., Chung W., Parry-Jones E., Anderson K., Mcforrester A., Stanley A., Hoather A., Wise H., Laid I., Scriven J., Braniste A., Wilson A., Le Blevec L., Pakunwanich N., Evans N., Chong H. L., White C., Hunter J., Haque M., Vanalia P., Murdoch S., Choudhary T., McCann A., Harun A., Shah H., Hunt S., Shafiq Y., Bickley-Morris E., Emms L., Dare M., Akula Y., Deliyannis E., Mayes F., Ellacott M., Zagorac Z., Farren A., Manning C., Hughed C., Stewart E. G., Lim K. 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F., Gazo Martinez J., Vicario Bravo M., Chavarrias N., Gil Catalan A., Oseira A., Villalonga B., Jeri S., Perez Calvo J., Nogues A., Cros B., Yanez C., Utrilla Fornals A., Roldon Golet M., Colsa P., Gimenez Maurel T., Axmarker T., Chevallay M., Pham T. V., Sel E. K., Atar C., Aba M., Sarkin M., Akkaya Y. M., Durmaz A. G., Gullu H. F., Boga A., Aktas A., Bakar B., Demirel M. T., Hysejni X., Taser M., Guzel O. R., Bozbiyik O., Ozen D., Olmez M., Uyar B., Gulcek E., Kayacan G. S., Atici N., Gul O. F., Altiner S., Ibis B., Altunsu S., Banaz T., Diler C., Demirbas I., Usta M. A., Erkul O., Orman R., Salih S., Utkan N. Z., Acil C., Ozgur E., Maddahali M., Turhan A. B., Eskici A. B., Ular B., Dogru M., Ozturk O. U., Arslan E. R., Panahi Sharif A., Dikmen E., Ates J., Bircan R., Cavus T., Sever A. E., Balak B., Duman E., Altay L., Emanet O., Cullen F., Tan J. Y., Nathan A., Rottenberg A., Williams C. Y., Mitrofan C. G., Xu D., Bawa J. H., Morris P., Gordon D., Richmond G., Hui J. 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S., Szal A., Khan A., O'Sullivan C., Baker E., Joseph-Gubral J., Hadley E., Trivedi R., Igwelaezoh E., Barton H., Allison W., Hurst W., Alam F., Parkes I., Jamshaid M., Azizan N., Burgher T., Afzal A., Eltilib I., Zahid M., Sadiq O., Lloyd A., Ho R., Brazukas A., Li C. H., Kamdar M., Mohamed Nazeer M. N., Mighiu A., Kim D., Wilkins L., Kuo L., Rafe T., Maduka D., Cheema H., Farag K., Abdellatif M., Nzewi R., Kruczynska A., Grasselli H., Yousuff M., Bassi R., Mann A. K., Chopra J., Shaikh M., D Sa S., Tsimplis V., Ghanchi A., Skene E., Asim K., Zaheer M., Chan S., Dalton H., Gibbons K., Adderley O., Chukwujindu I., Jayasuriya I., Sivanu K., Borumand M., Chick G., Bridges I., Tomlin J., McKenna J., Nandra N., Grieco C., Quek F. F., Mercer R., Brankin-Frisby T., Sattar A., Aslam A., Edelsten E., Shafi S., Kouli T., Ford V., Gurung F., Fernandes M., Deader N., Ponniah R., Jamieson S., Davies A., Taubwurcel J., Aung M. T., Desai R., Begum S., Jamadar T., Kangatharan A., Rzeszowski B., Ho C., Yap S. H. K., Prendergast M., Sethi R., Duku A., Lowe C., Bray J., Ghobrial M., Nichita V., Wagstaff A., Rengasamy E., Abu Hassan F., Mahmood H., Savill N., Shah S., Almeida T., Edwards A., Catchpole B., Halford Z., Carmichael A., Alsusa H., Boyd M., Williams J., Feyi-Waboso J., Patel M., Zeidan Z., Bailey E., Bapty J., Brazkiewicz M., Tremlett A., Pringle H., Mankal S., Chung W., Parry-Jones E., Anderson K., Mcforrester A., Stanley A., Hoather A., Wise H., Laid I., Scriven J., Braniste A., Wilson A., Le Blevec L., Pakunwanich N., Evans N., Chong H. L., White C., Hunter J., Haque M., Vanalia P., Murdoch S., Choudhary T., McCann A., Harun A., Shah H., Hunt S., Shafiq Y., Bickley-Morris E., Emms L., Dare M., Akula Y., Deliyannis E., Mayes F., Ellacott M., Zagorac Z., Farren A., Manning C., Hughed C., Stewart E. G., Lim K. H., Chohan N., Thaker A., Thompson B., Ahari D., Burdekin E., Okwu U., Akintunde A., Lhaf F., Douthwaite J., Govindan R., Leelamanthep S., Gull E., Wright F., Dundas L., Mackdermott N., Burchi-Khairy T., Campbell I., Walsh J., Yeo J. Y., Meehan S., Banerjee D., Fu M., Kawka M., Ali T., Hussain Z., Thomas C., Ahmad H., Moroney J., Yick C., Risquet R., Ntuiabane D., Shimato M., Khan M., Ilangovan S., Vaselli N. M., Smithers R., Uhanowita Marage R., Valnarov-Boulter A., Kayran J., Banerjee M., Parekh-Hill N., Hooper A., Bowen J., Jagdish R., Mcquoid C., Khan N., O Hare R., Jeffery S., Zahid A., Elsworth C., Walter L., Dhillon S., Rao S., Anthony A., Ashaye A., Phillips N., Faderani R., Pengelly S., Choi S., Kwak S. Y., Lau Y. H. L., Bagheri K., Ong D. Y. C., Kerr E., Falconer K., Clancy N., Douglas S., Zhang Y., Greenfield F., Mutanga I., McAlinden J., Willis L., Adefolaju A., Agarwal H., Barter R., Harris G., Spencer G., Lee M. 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A., Kurtenkov M., Jovanovic M., Vician M., Egea Arias P., Beltran de Heredia J., Labalde Martinez M., De Santiago Alvarez I., Alvarez-Gallego M., Rodriguez Artigas J. M., Dwidar O., Korkmaz H. K., Eray I. C., Meric S., Aydin R., Cetin B., Karaca B. E., Kuyumcu O. F., Yuksel E., Uprak T. K., Karabulut K., Kavukcu E., Mansor A., Hackett R., Zammit-Maempel M., Sabaratnam R., Maan A., Ferarrio I., Dixon L., Halai H., Sethi S., Nelson L., Grassam-rowe A., Krishnan E., Deeny D., McKeever M., George Pandeth A., Dhavala P., Sreenivasan S., Sundaram Venkatesan G., Zhu L., Atiyah Z., Gregory J., Morey T., Seymour Z., Holdsworth L., Abdelmahmoud S., Bourhill J., Bisheet G., Shaw J., Kulkarni K., Kumarakulasingam P., Pillay S., Al-Habsi R., Kungwengwe G., Richards J., Davoudi K., Ibrahim B., Tailor B., Zayed M., Chen F., Bailey S., Sheefat S., Nawaz G., Pawar R., Marsh S., Sam Z. H., Roy Bentley S., Simpson C., Hughes J., Lim Y., Ooi R., Toh W. H., Mannion P., Lovett A., Kincius A., Hussein S., Kirby E., Beckett R. G., Salmon J., Glynn T., Choo S. Y., Lyons S., Browne D., Ravindran W., Ahmad S., Zhu X., McNulty J., McCarthy L., Ng J., Karmally Z., McTeir K., Hanna M., Tan E., Namdeo S., Schembri R., and Pusey E.
- Abstract
Aim: Intraperitoneal drains are often placed during emergency colorectal surgery. However, there is a lack of evidence supporting their use. This study aimed to describe the efficacy and safety of intraperitoneal drain placement after emergency colorectal surgery. Method: COMPlicAted intra-abdominal collectionS after colorectal Surgery (COMPASS) is a prospective, international, cohort study into which consecutive adult patients undergoing emergency colorectal surgery were enrolled (from 3 February 2020 to 8 March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included rate and time-to-diagnosis of postoperative intraperitoneal collections, rate of surgical site infections (SSIs), time to discharge and 30-day major postoperative complications (Clavien–Dindo III–V). Multivariable logistic and Cox proportional hazards regressions were used to estimate the independent association of the outcomes with drain placement. Results: Some 725 patients (median age 68.0 years; 349 [48.1%] women) from 22 countries were included. The drain insertion rate was 53.7% (389 patients). Following multivariable adjustment, drains were not significantly associated with reduced rates (odds ratio [OR] = 1.56, 95% CI: 0.48–5.02, p = 0.457) or earlier detection (hazard ratio [HR] = 1.07, 95% CI: 0.61–1.90, p = 0.805) of collections. Drains were not significantly associated with worse major postoperative complications (OR = 1.26, 95% CI: 0.67–2.36, p = 0.478), delayed hospital discharge (HR = 1.11, 95% CI: 0.91–1.36, p = 0.303) or increased risk of SSIs (OR = 1.61, 95% CI: 0.87–2.99, p = 0.128). Conclusion: This is the first study investigating placement of intraperitoneal drains following emergency colorectal surgery. The safety and clinical benefit of drains remain uncertain. Equipoise exists for randomized trials to define the safety and efficacy of drains in emergency colorectal surgery.
- Published
- 2023
3. Intraperitoneal drain placement and outcomes after elective colorectal surgery: International matched, prospective, cohort study
- Author
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S., Top C., Detering R., Matos C., Silva C., Pinto D., Mendes J., Couto J., Leite M., Velez C., Damasio Cotovio M., Cinza A. M., Pedroso de Lima R., Boyle E., Yang H. W., Banerjee I., Rahmat S., Afzal Z., Reid C., Dumitrascu F., Croyle J. A., Gressmann K., Cullen N., Graham A., Nasehi A., Montano King C., Martin B., Stokell C., Sanderson N., Farnan R., Jassim S., Chan B., Chua Vi Long K., Kaka N., Pandey S., Neo W. X., Chitul A., Bezede C., Cincilei D., David A., Blaga M., Blaga S. N., Fagarasan V., Khetagurova M., Rodimov S., Kapustina A., Mekhralyzade A., Zabiyaka M., Jankovic U., Cuk V., Hajska M., Dubovsky M., Hrosova M., Ferancikova N., Camarero Rodriguez E., Laguna Alcantara F., Adarraga J., Jezieniecki C., Ruiz Soriano M., Gomez Sanz T., Suarez A., Sanchez Garcia C., Cifrian Canales I., Llosa Perez J., Merayo M., Urbieta A., Gegundez Simon A., Tone J. F., Gazo Martinez J., Vicario Bravo M., Chavarrias N., Gil Catalan A., Oseira A., Villalonga B., Jeri S., Perez Calvo J., Nogues A., Cros B., Yanez C., Utrilla Fornals A., Roldon Golet M., Colsa P., Gimenez Maurel T., Axmarker T., Chevallay M., Pham T. V., Sel E. K., Atar C., Aba M., Sarkin M., Akkaya Y. M., Durmaz A. G., Gullu H. F., Boga A., Aktas A., Bakar B., Demirel M. T., Hysejni X., Taser M., Guzel O. R., Bozbiyik O., Ozen D., Olmez M., Uyar B., Gulcek E., Kayacan G. S., Atici N., Gul O. F., Altiner S., Ibis B., Altunsu S., Banaz T., Diler C., Demirbas I., Usta M. A., Erkul O., Orman R., Salih S., Utkan N. Z., Acil C., Ozgur E., Maddahali M., Turhan A. B., Eskici A. B., Ular B., Dogru M., Ozturk O. U., Arslan E. R., Panahi Sharif A., Dikmen E., Ates J., Bircan R., Cavus T., Sever A. E., Balak B., Duman E., Altay L., Emanet O., Cullen F., Tan J. Y., Nathan A., Rottenberg A., Williams C. Y., Mitrofan C. G., Xu D., Bawa J. H., Morris P., Gordon D., Richmond G., Hui J. C., Ighomereho O., Rocks R., McCabe S., Fitzpatrick A., Nicoletti J., Auterson L., Darrah N., Soh V. W. Y., Ong C. S., Utukuri M., Gallagher C., Stuart L. M., Hipolito M., Douglas N., Ghazal R., Parris G., Catchpole J., Bryden M., Jamal S., Karim Z., Lyon-Dean C., Rowley G., Lee K. S., Whitehurst O., Mirza A., Sheikh F., Yousaf H., Bilbao J., Sinclair R., Takar S., Kressel H., Chan V., Schack K., Osborne R., Baldemor S., Smyth S., Gilmour S., Ting A., Bozonelou I., Saunders P., Qhaireel Anwar Q. A., Tirimanna R., Jauhari S., Gardener A., Walker B., Wenban C., Reddy H., Conway-Jones R., Loganathan S., Clynch A., James C., Matey E., Cameron F., Roberts W., Gicquel A., Milliken C., Forbes J., Rubinchik P., Azmi A., Hawkes C., Cornett L., Adarkwah P., McConville R., O'Hara S., Tijare C., Parkes J., Yao L., Ahmad R., Shafiq U., Mhaisalkar A., Gurung A., de Stadler K., Elias S., Thomas T., Madras A., Jani A., Daler H. K., Tong K. S., Sundaralingam S. S., Szal A., Khan A., O'Sullivan C., Baker E., Joseph-Gubral J., Hadley E., Trivedi R., Igwelaezoh E., Barton H., Allison W., Hurst W., Alam F., Parkes I., Jamshaid M., Azizan N., Burgher T., Afzal A., Eltilib I., Zahid M., Sadiq O., Lloyd A., Ho R., Brazukas A., Li C. H., Kamdar M., Mohamed Nazeer M. N., Mighiu A., Kim D., Wilkins L., Kuo L., Rafe T., Maduka D., Cheema H., Farag K., Abdellatif M., Nzewi R., Kruczynska A., Grasselli H., Yousuff M., Bassi R., Mann A. K., Chopra J., Shaikh M., Sa D. S., Tsimplis V., Ghanchi A., Skene E., Asim K., Zaheer M., Chan S., Dalton H., Gibbons K., Adderley O., Chukwujindu I., Jayasuriya I., Sivanu K., Borumand M., Chick G., Bridges I., Tomlin J., McKenna J., Nandra N., Grieco C., Quek F. F., Mercer R., Brankin-Frisby T., Sattar A., Aslam A., Edelsten E., Shafi S., Kouli T., Ford V., Gurung F., Fernandes M., Deader N., Ponniah R., Jamieson S., Davies A., Taubwurcel J., Aung M. T., Desai R., Begum S., Jamadar T., Kangatharan A., Rzeszowski B., Ho C., Yap S. H. K., Prendergast M., Sethi R., Duku A., Lowe C., Bray J., Ghobrial M., Nichita V., Wagstaff A., Rengasamy E., Abu Hassan F., Mahmood H., Savill N., Shah S., Almeida T., Edwards A., Catchpole B., Halford Z., Carmichael A., Alsusa H., Boyd M., Williams J., Feyi-Waboso J., Patel M., Zeidan Z., Bailey E., Bapty J., Brazkiewicz M., Tremlett A., Pringle H., Mankal S., Chung W., Parry-Jones E., Anderson K., McForrester A., Stanley A., Hoather A., Wise H., Laid I., Scriven J., Braniste A., Wilson A., Le Blevec L., Pakunwanich N., Evans N., Chong H. L., White C., Hunter J., Haque M., Vanalia P., Murdoch S., Choudhary T., McCann A., Harun A., Shah H., Hunt S., Shafiq Y., Bickley-Morris E., Emms L., Dare M., Akula Y., Deliyannis E., Mayes F., Ellacott M., Zagorac Z., Farren A., Manning C., Hughed C., Stewart E. G., Lim K. H., Chohan N., Thaker A., Thompson B., Ahari D., Burdekin E., Okwu U., Akintunde A., Lhaf F., Douthwaite J., Govindan R., Leelamanthep S., Gull E., Wright F., Dundas L., Mackdermott N., Burchi-Khairy T., Campbell I., Walsh J., Yeo J. Y., Meehan S., Banerjee D., Fu M., Kawka M., Ali T., Hussain Z., Thomas C., Ahmad H., Moroney J., Yick C., Risquet R., Ntuiabane D., Shimato M., Khan M., Ilangovan S., Vaselli N. M., Smithers R., Uhanowita Marage R., Valnarov-Boulter A., Kayran J., Banerjee M., Parekh-Hill N., Hooper A., Bowen J., Jagdish R., McQuoid C., Khan N., O'Hare R., Jeffery S., Zahid A., Elsworth C., Walter L., Dhillon S., Rao S., Anthony A., Ashaye A., Phillips N., Faderani R., Pengelly S., Choi S., Kwak S. Y., Lau Y. H. L., Bagheri K., Ong D. Y. C., Kerr E., Falconer K., Clancy N., Douglas S., Zhang Y., Greenfield F., Mutanga I., McAlinden J., Willis L., Adefolaju A., Agarwal H., Barter R., Harris G., Spencer G., Lee M. W., Vadiveloo V. T., Herbert G., Patel R., Shah M., El Falaha S., Wong C., Soare C., Akram J., Bozhkova L., Ma Y., Vo U. G., Tan H. W. N., Leto L., Kamal M. A., Hadzhieva E., Krastev P., Tonchev P., Kokkinos G., Pozotou I., Sabbagh D., Votava J., St F., Koliakos N., Tsaparas P., Zografos G., Mantas D., Tsourouflis G., Fradelos E., Trigiante G., Labellarte G., Resta G., Capelli G., D'Amore A., Verlingieri V., Campagnaro T., Maffioli A., Viscosi F., De Lucia C., Meneghini S., Fancellu A., Colella M., Biondi A., De Peppo V., Pace U., Albino V., Gattulli D., Piangerelli A., Kalivaci D., Sisto G., Mazzola M., Caneparo A., Lunghi E. G., Nespoli L. C., Angrisani M., Langone A., Gelarda E., Virgilio E., Angelini E., Fornasier C., Asero S., Filippone E., Frongia F., Calo P. G., Panaccio P., Ipponi P., Gili S., Braccio B., Tiesi V., Stolcers K., Kokaine L., Novikovs V., Capel L., Bastiaenen V., Heijmans H., Henriques S., Gan S. Z., Ramanayake H., Nolan M., Temperley H., Ciofic E., Pop B. A., Kurtenkov M., Jovanovic M., Vician M., Egea Arias P., Beltran de Heredia J., Labalde Martinez M., De Santiago Alvarez I., Alvarez-Gallego M., Rodriguez Artigas J. M., Dwidar O., Korkmaz H. K., Eray I. C., Meric S., Aydin R., Cetin B., Karaca B. E., Kuyumcu O. F., Yuksel E., Uprak T. K., Karabulut K., Kavukcu E., Mansor A., Hackett R., Zammit-Maempel M., Sabaratnam R., Maan A., Ferarrio I., Dixon L., Halai H., Sethi S., Nelson L., Grassam-Rowe A., Krishnan E., Deeny D., McKeever M., George Pandeth A., Dhavala P., Sreenivasan S., Sundaram Venkatesan G., Zhu L., Atiyah Z., Gregory J., Morey T., Seymour Z., Holdsworth L., Abdelmahmoud S., Bourhill J., Bisheet G., Shaw J., Kulkarni K., Kumarakulasingam P., Pillay S., Al-Habsi R., Kungwengwe G., Richards J., Davoudi K., Ibrahim B., Tailor B., Zayed M., Chen F., Bailey S., Sheefat S., Nawaz G., Pawar R., Marsh S., Sam Z. H., Roy Bentley S., Simpson C., Hughes J., Lim Y., Ooi R., Toh W. H., Mannion P., Lovett A., Kincius A., Hussein S., Kirby E., Beckett R. G., Salmon J., Glynn T., Choo S. Y., Lyons S., Browne D., Ravindran W., Ahmad S., Zhu X., McNulty J., McCarthy L., Ng J., Karmally Z., McTeir K., Hanna M., Tan E., Namdeo S., Schembri R., and Pusey E.
- Abstract
Despite current guidelines, intraperitoneal drain placement after elective colorectal surgery remains widespread. Drains were not associated with earlier detection of intraperitoneal collections, but were associated with prolonged hospital stay and increased risk of surgical-site infections.Background Many surgeons routinely place intraperitoneal drains after elective colorectal surgery. However, enhanced recovery after surgery guidelines recommend against their routine use owing to a lack of clear clinical benefit. This study aimed to describe international variation in intraperitoneal drain placement and the safety of this practice. Methods COMPASS (COMPlicAted intra-abdominal collectionS after colorectal Surgery) was a prospective, international, cohort study which enrolled consecutive adults undergoing elective colorectal surgery (February to March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included: rate and time to diagnosis of postoperative intraperitoneal collections; rate of surgical site infections (SSIs); time to discharge; and 30-day major postoperative complications (Clavien-Dindo grade at least III). After propensity score matching, multivariable logistic regression and Cox proportional hazards regression were used to estimate the independent association of the secondary outcomes with drain placement. Results Overall, 1805 patients from 22 countries were included (798 women, 44.2 per cent; median age 67.0 years). The drain insertion rate was 51.9 per cent (937 patients). After matching, drains were not associated with reduced rates (odds ratio (OR) 1.33, 95 per cent c.i. 0.79 to 2.23; P = 0.287) or earlier detection (hazard ratio (HR) 0.87, 0.33 to 2.31; P = 0.780) of collections. Although not associated with worse major postoperative complications (OR 1.09, 0.68 to 1.75; P = 0.709), drains were associated with delayed hospital discharge (HR 0.58, 0.52 to 0.66; P < 0.001) and an increased risk of S
- Published
- 2022
4. Intraperitoneal drain placement and outcomes after elective colorectal surgery: International matched, prospective, cohort study
- Author
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Sgro A., Blanco-Colino R., Ahmed W. U. R., Brindl N., Gujjuri R. R., Lapolla P., Mills E. C., Perez-Ajates S., Soares A. S., Varghese C., Xu W., McLean K. A., Chapman S. J., Espin-Basany E., Glasbey J. C., Mihaljevic A., Nepogodiev D., Pata F., Pellino G., Pockney P., Dudi-Venkata N. N., Egoroff N., Ludbrook I., Raubenheimer K., Richards T., Delibegovic S., Salibasic M., Amjad T., Dorr-Harim C., Gedeon N., Gsenger J., Tachezy M., Bini S., Gallo G., Gori A., Picciariello A., Podda M., Riboni C., Machatschek M. J., Nguyen A., Jakubauskas M., Kryzauskas M., Poskus T., Kuiper S. Z., Wang J., Wells C. I., Bissett I. P., Augestad K. M., Steinholt I., Vieira B. N., Juloski J., Anabitarte Bautista O., El Kasmy El Kasmy Y., Martin-Borregon P., Ossola Revilla M., Van Straten S., Aktas M. K., Baki B. E., Akhbari M., Baker D., Bhatia S., Brown S., Cambridge W., Kamarajah S. K., Khaw R. A., Kouli O., Murray V., Trout I., Yasin I., Wong J. Y., Reyhani H., Wong K. H. F., Pancharatnam R., Chia W. L., Walmsley A., Hassane A., Saeed D., Wang B., Walters B., Nowinka Z., Alsaif A., Mirza M., Foster K., Luu J., Kakodkar P., Hughes J. T., Yogarajah T., Antypas A., Rahman A., Bradbury M., McLarnon M., Nagi S., Riad A. M., Erotocritou M., Kyriacou H., Kaminskaite V., Alfadhel S., Fatimah Hussain Q., Handa A., Massy-Westropp C., Custovic S., Dimov R., Mughal H., Slavchev M., Ivanov T., Gouvas N., Hegazi A., Kocian P., Kjaer M. D., Mark-Christensen A., Papakonstantinou D., Machairas N., Triantafyllou T., Garoufalia Z., Korkolis D., Castaldi A., Giaccari S., Spolverato G., Pagano G., Milone M., Turri G., Colombo F., Cucinotta E., Poillucci G., Perra T., Tutino R., Belia F., Coletta D., Belli A., Rega D., Cianci P., Pirozzolo G., Di Lena M., Perrone F., Giani A., Lovisetto F., Grassia M., Pipitone Federico N. S., Ferrara F., Biancafarina A., Tamini N., Sinibaldi G., Tuminello F., Galleano R., Sasia D., Bragaglia L., de Manzoni Garberini A., Pesce A., Cassaro F., Venturelli P., Canu G. L., Esposito G., Campanelli M., Cardia R., Ricciardiello M., Sagnotta A., Canonico G., De Marco G., Cappiello A., Pinotti E., Carlei F., Lisi G., Bagaglini G., Farrugia M., Meima-Van Praag E. M., Monteiro C., Pereira M., Botelho P., Quigley A., O'Neill A., Gaule L., Crone L., Arnold A., Grama F., Beuca A., Tulina I., Litvin A., Panyko A., Ossola M. E., Trujillo Diaz J., Marin Santos J. M., Alonso Batanero E., Gortazar de las Casas S., Soldevila Verdeguer C., Colas-Ruiz E., Talal El-Abur I., Garcia Dominguez M., Delorme M., Sauvain M., Ozmen B. B., Ozkan B. B., Calikoglu F., Kural S., Zafer F., Kaya Y., Yalcinkaya A., Kargici K., Tepe M. D., Tatar O. C., Kabadayi E., Yildirim A., Hurmuzlu D., Korkmaz K., Sharma P., Troller R., Hagan N., Mooney J., Light A., Tansey M., Bhojwani D., McGing R. M., Mallon A., Fadel M., Spilsbury C., James R., O'Brien S., Isaac A., Balasubramanya S., Sadik H., Gala T., Chen J. Y., Turner B., Goh E., Hassan K., Karam M., Mason P., Tzoumas N., Noton T., Seehra J. K., Ahmed N., Motiwale R., Tanna V., Argyriou A., Bylapudi S. K., Grace N., Latif S., Hounat A., Kiam J. S., Zaidi M., Elsamani K., Hughes C., Suresh A., Sinan L. O. H., El-Dalil D., Khoo E. J. M., Salim E. E., Stark D., Minhas N., Fowler G., Rees E., Giudiceandrea I., Bardon A., Jayawardena P., Dieseru N., Murphy A., Yates C., Ziolkowska K., Rafie A., Khoda F., Okocha M., Ashdown T., Vitish-Sharma P., Gilliland J., Toh S., Jones K., Devine A., Berry A., McDonnell S., Olivier J., Richardson G., Lim H. J., Slim N., Elsayeh K., Sammour T., Sarpanov A., Belev N., Dimitrov D., Dusek T., Ntomi V., Sotiropoulos G. C., Theodorou D., Nikiteas N., Balalis D., Antropoli C., Altomare D. F., Luglio G., De Palma G. D., Pedrazzani C., Simonelli L., Brozzetti S., Porcu A., Massani M., Grazi G. L., Izzo F., Delrio P., Restini E., Chetta G., Lantone G., Ferrari G., Lucchi A., De Prizio M., Caristo G., Borghi F., Petrucciani N., Huscher C., Cocorullo G., Tonini V., Medas F., Sica G., Cillara N., Anastasi A., Bianco F., Giuliani A., Carlini M., Selvaggi F., Sammarco G., Ozolins A., Malasonoks A., Andrejevic P., Tanis P., van de Ven A., Gerhards M., Ribeiro da Silva B., Silva A., Lima M. J., Kavanagh D., McCawley N., Bintintan V., Karamarkovic A., Sanz Ortega G., De Andres-Asenjo B., Nevado Garcia C., Garcia Florez L. J., Segura-Sampedro J. J., Blas Laina J. L., Ponchietti L., Buchwald P., Gialamas E., Ozben V., Rencuzogullari A., Gecim I. E., Altinel Y., Isik O., Yoldas T., Isik A., Leventoglu S., Erturk M. S., Guner A., Guler S. A., Attaallah W., Ugur M., Ozbalci G. S., Marzook H., Eardley N., Smolarek S., Morgan R., Roxburgh C., Lala A. K., Salama Y., Singh B., Khanna A., Evans M., Shaikh I., Maradi Thippeswamy K., Appleton B., Moug S., Smith I., Smart N., Shah P., Williams G., Khera G., Goede A., Varcada M., Parmar C., Duff S., Hargest R., Marriott P., Speake D., Ben Sassi A., Furfaro B., Daudu D., Golijanin N., Yek W. Y., Capasso G., Mansour L. T., Niu N., Seow W., Hamidovic A., Kulovic E., Letic E., Aljic A., Helez M., Banji-Kelan A., Dimitrova N., Kavradjieva P., Ivanov V., Jukaku A., Hadzhiev D., Gabarski A., Karamanliev M., Vladova P., Iliev S., Yotsov T., Vetsa K., Stavrinidou O., Papatheodorou P., Liassides T., Georgiou T., Al Nassrallah M., Altaf R., Negametzyanov M., Zagibova D., Foltys F., Stefanova H., Paspala A., Bompetsi G., Sidiropoulos T., Stamopoulos P., Triantafyllou A., Theodoropoulos C., Kimpizi A., Palyvou T., Charalabopoulos A., Syllaios A., Schizas D., Liatsou E., Baili E., Vagios I., Tomara N., Davakis S., Palumbo A., Foroni F., Dibra R., Papagni V., Urbani A., Rossin E., Nezi G., Romano P., Amendola A., Esposito E., Manigrasso M., Anoldo P., Vertaldi S., Gecchele G., Sabrina Z. S., Guerci C., Cammarata F., Lamperti G. M. B., Zaffaroni G., Benuzzi L., Ferrario L., Cigognini M., Mazzeo C., Badessi G., Pintabona G., Fassari A., Mingoli A., Cirillo B., D'Alterio C., Brachini G., Tancredi M., Zambon M., Aulicino M., Sapienza P., Liberatore P., Scanu A. M., Feo C. F., Iacomino A., Pelizzo P., Rossi S., Vigna S. A., Grossi U., Grillo V., Agnes A., Schena C. A., Marincola G., Oddi A., Perotti B., Mario V., Perri P., Zazza S., Aversano A., Scala D., Di Lauro K., Leongito M., Piccirillo M., Patrone R., Capuzzolo S., Vignotto C., Bao Q. R., Giuseppe C., Angarano E., Marino F., Pezzolla F., Gigante G., Magistro C., Crippa J., Maspero M., Carnevali P., Trapani R., Zonta S., Agostinelli L., Vittori L., Romeo L., Doria E., Farnesi F., Danna R., Andolfi E., Pellicano' G. A., Angelini M., Scricciolo M., Zanframundo C., Ciulli C., Ripamonti L., Cigagna L., Oldani M., Larcinese A., Rossi D., Picone E., Crescentini G., Marano A., Migliore M., Giuffrida M. C., Palagi S., Testa V., Borrello A., Lucarini A., Garofalo E., Canali G., Orlandi P., Nervegna F., Marchegiani F., Damoli I., Licata A., Trovato C., Alicata F., Sardo F., Milazzo M., Randisi B., Dominici D. M., Sartarelli L., Zanni M., Pisanu A., Soddu C., Delogu D., Erdas E., Campus F., Cappellacci F., Casti F., Marcialis J., Atzeni J., Podda M. G., Sensi B., Franceschilli M., Bellato V., Cannavera A., Putzu G., di Mola F. F., Picardi B., Solinas L., Loponte M., Rossi del Monte S., Di Martino C., Linari C., Spagni G., Capezzuoli L., Tirloni L., Nelli T., Caridi A., Elter C., Camassa M., D'Amico S., Bargellini T., Incollingo P., Montuori M., Maffione F., Romano L., Valiyeva S., Spoletini D., Menegon Tasselli F., Sciaudone G., Selvaggi L., Menna M. P., De Paola G., Fulginiti S., Truskovs A., Weiss C., Saknitis G., Rauscher J. T. R., Larnovskis J., Jeyarajan-Davidsson M., Nitisa D., Gille N., Reiser S. C., Roshan M. H. K., Leseman C., Chen J., van Dalen A. S., Top C., Detering R., Matos C., Silva C., Pinto D., Mendes J., Couto J., Leite M., Velez C., Damasio Cotovio M., Cinza A. M., Pedroso de Lima R., Boyle E., Yang H. W., Banerjee I., Rahmat S., Afzal Z., Reid C., Dumitrascu F., Croyle J. A., Gressmann K., Cullen N., Graham A., Nasehi A., Montano King C., Martin B., Stokell C., Sanderson N., Farnan R., Jassim S., Chan B., Chua Vi Long K., Kaka N., Pandey S., Neo W. X., Chitul A., Bezede C., Cincilei D., David A., Blaga M., Blaga S. N., Fagarasan V., Khetagurova M., Rodimov S., Kapustina A., Mekhralyzade A., Zabiyaka M., Jankovic U., Cuk V., Hajska M., Dubovsky M., Hrosova M., Ferancikova N., Camarero Rodriguez E., Laguna Alcantara F., Adarraga J., Jezieniecki C., Ruiz Soriano M., Gomez Sanz T., Suarez A., Sanchez Garcia C., Cifrian Canales I., Llosa Perez J., Merayo M., Urbieta A., Gegundez Simon A., Tone J. F., Gazo Martinez J., Vicario Bravo M., Chavarrias N., Gil Catalan A., Oseira A., Villalonga B., Jeri S., Perez Calvo J., Nogues A., Cros B., Yanez C., Utrilla Fornals A., Roldon Golet M., Colsa P., Gimenez Maurel T., Axmarker T., Chevallay M., Pham T. V., Sel E. K., Atar C., Aba M., Sarkin M., Akkaya Y. M., Durmaz A. G., Gullu H. F., Boga A., Aktas A., Bakar B., Demirel M. T., Hysejni X., Taser M., Guzel O. R., Bozbiyik O., Ozen D., Olmez M., Uyar B., Gulcek E., Kayacan G. S., Atici N., Gul O. F., Altiner S., Ibis B., Altunsu S., Banaz T., Diler C., Demirbas I., Usta M. A., Erkul O., Orman R., Salih S., Utkan N. Z., Acil C., Ozgur E., Maddahali M., Turhan A. B., Eskici A. B., Ular B., Dogru M., Ozturk O. U., Arslan E. R., Panahi Sharif A., Dikmen E., Ates J., Bircan R., Cavus T., Sever A. E., Balak B., Duman E., Altay L., Emanet O., Cullen F., Tan J. Y., Nathan A., Rottenberg A., Williams C. Y., Mitrofan C. G., Xu D., Bawa J. H., Morris P., Gordon D., Richmond G., Hui J. C., Ighomereho O., Rocks R., McCabe S., Fitzpatrick A., Nicoletti J., Auterson L., Darrah N., Soh V. W. Y., Ong C. S., Utukuri M., Gallagher C., Stuart L. M., Hipolito M., Douglas N., Ghazal R., Parris G., Catchpole J., Bryden M., Jamal S., Karim Z., Lyon-Dean C., Rowley G., Lee K. S., Whitehurst O., Mirza A., Sheikh F., Yousaf H., Bilbao J., Sinclair R., Takar S., Kressel H., Chan V., Schack K., Osborne R., Baldemor S., Smyth S., Gilmour S., Ting A., Bozonelou I., Saunders P., Qhaireel Anwar Q. A., Tirimanna R., Jauhari S., Gardener A., Walker B., Wenban C., Reddy H., Conway-Jones R., Loganathan S., Clynch A., James C., Matey E., Cameron F., Roberts W., Gicquel A., Milliken C., Forbes J., Rubinchik P., Azmi A., Hawkes C., Cornett L., Adarkwah P., McConville R., O'Hara S., Tijare C., Parkes J., Yao L., Ahmad R., Shafiq U., Mhaisalkar A., Gurung A., de Stadler K., Elias S., Thomas T., Madras A., Jani A., Daler H. K., Tong K. S., Sundaralingam S. S., Szal A., Khan A., O'Sullivan C., Baker E., Joseph-Gubral J., Hadley E., Trivedi R., Igwelaezoh E., Barton H., Allison W., Hurst W., Alam F., Parkes I., Jamshaid M., Azizan N., Burgher T., Afzal A., Eltilib I., Zahid M., Sadiq O., Lloyd A., Ho R., Brazukas A., Li C. H., Kamdar M., Mohamed Nazeer M. N., Mighiu A., Kim D., Wilkins L., Kuo L., Rafe T., Maduka D., Cheema H., Farag K., Abdellatif M., Nzewi R., Kruczynska A., Grasselli H., Yousuff M., Bassi R., Mann A. K., Chopra J., Shaikh M., Sa D. S., Tsimplis V., Ghanchi A., Skene E., Asim K., Zaheer M., Chan S., Dalton H., Gibbons K., Adderley O., Chukwujindu I., Jayasuriya I., Sivanu K., Borumand M., Chick G., Bridges I., Tomlin J., McKenna J., Nandra N., Grieco C., Quek F. F., Mercer R., Brankin-Frisby T., Sattar A., Aslam A., Edelsten E., Shafi S., Kouli T., Ford V., Gurung F., Fernandes M., Deader N., Ponniah R., Jamieson S., Davies A., Taubwurcel J., Aung M. 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Hoather A., Wise H., Laid I., Scriven J., Braniste A., Wilson A., Le Blevec L., Pakunwanich N., Evans N., Chong H.L., White C., Hunter J., Haque M., Vanalia P., Murdoch S., Choudhary T., McCann A., Harun A., Shah H., Hunt S., Shafiq Y., Bickley-Morris E., Emms L., Dare M., Akula Y., Deliyannis E., Mayes F., Ellacott M., Zagorac Z., Farren A., Manning C., Hughed C., Stewart E.G., Lim K.H., Chohan N., Thaker A., Thompson B., Ahari D., Burdekin E., Okwu U., Akintunde A., Lhaf F., Douthwaite J., Govindan R., Leelamanthep S., Gull E., Wright F., Dundas L., Mackdermott N., Burchi-Khairy T., Campbell I., Walsh J., Yeo J.Y., Meehan S., Banerjee D., Fu M., Kawka M., Ali T., Hussain Z., Thomas C., Ahmad H., Moroney J., Yick C., Risquet R., Ntuiabane D., Shimato M., Khan M., Ilangovan S., Vaselli N.M., Smithers R., Uhanowita Marage R., Valnarov-Boulter A., Kayran J., Banerjee M., Parekh-Hill N., Hooper A., Bowen J., Jagdish R., McQuoid C., Khan N., O'Hare R., Jeffery S., Zahid A., Elsworth C., Walter L., Dhillon S., Rao S., Anthony A., Ashaye A., Phillips N., Faderani R., Pengelly S., Choi S., Kwak S.Y., Lau Y.H.L., Bagheri K., Ong D.Y.C., Kerr E., Falconer K., Clancy N., Douglas S., Zhang Y., Greenfield F., Mutanga I., McAlinden J., Willis L., Adefolaju A., Agarwal H., Barter R., Harris G., Spencer G., Lee M.W., Vadiveloo V.T., Herbert G., Patel R., Shah M., El Falaha S., Wong C., Soare C., Akram J., Bozhkova L., Ma Y., Vo U.G., Tan H.W.N., Leto L., Kamal M.A., Hadzhieva E., Krastev P., Tonchev P., Kokkinos G., Pozotou I., Sabbagh D., Votava J., St F., Koliakos N., Tsaparas P., Zografos G., Mantas D., Tsourouflis G., Fradelos E., Trigiante G., Labellarte G., Resta G., Capelli G., D'Amore A., Verlingieri V., Campagnaro T., Maffioli A., Viscosi F., De Lucia C., Meneghini S., Fancellu A., Colella M., Biondi A., De Peppo V., Pace U., Albino V., Gattulli D., Piangerelli A., Kalivaci D., Sisto G., Mazzola M., Caneparo A., Lunghi E.G., Nespoli L.C., Angrisani M., Langone A., 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M., Hipolito, M., Douglas, N., Ghazal, R., Parris, G., Catchpole, J., Bryden, M., Jamal, S., Karim, Z., Lyon-Dean, C., Rowley, G., Lee, K. S., Whitehurst, O., Mirza, A., Sheikh, F., Yousaf, H., Bilbao, J., Sinclair, R., Takar, S., Kressel, H., Chan, V., Schack, K., Osborne, R., Baldemor, S., Smyth, S., Gilmour, S., Ting, A., Bozonelou, I., Saunders, P., Qhaireel Anwar, Q. A., Tirimanna, R., Jauhari, S., Gardener, A., Walker, B., Wenban, C., Reddy, H., Conway-Jones, R., Loganathan, S., Clynch, A., James, C., Matey, E., Cameron, F., Roberts, W., Gicquel, A., Milliken, C., Forbes, J., Rubinchik, P., Azmi, A., Hawkes, C., Cornett, L., Adarkwah, P., Mcconville, R., O'Hara, S., Tijare, C., Parkes, J., Yao, L., Ahmad, R., Shafiq, U., Mhaisalkar, A., Gurung, A., de Stadler, K., Elias, S., Thomas, T., Madras, A., Jani, A., Daler, H. K., Tong, K. S., Sundaralingam, S. S., Szal, A., Khan, A., O'Sullivan, C., Baker, E., Joseph-Gubral, J., Hadley, E., Trivedi, R., Igwelaezoh, E., Barton, H., Allison, W., Hurst, W., Alam, F., Parkes, I., Jamshaid, M., Azizan, N., Burgher, T., Afzal, A., Eltilib, I., Zahid, M., Sadiq, O., Lloyd, A., Ho, R., Brazukas, A., Li, C. H., Kamdar, M., Mohamed Nazeer, M. N., Mighiu, A., Kim, D., Wilkins, L., Kuo, L., Rafe, T., Maduka, D., Cheema, H., Farag, K., Abdellatif, M., Nzewi, R., Kruczynska, A., Grasselli, H., Yousuff, M., Bassi, R., Mann, A. K., Chopra, J., Shaikh, M., Sa, D. S., Tsimplis, V., Ghanchi, A., Skene, E., Asim, K., Zaheer, M., Chan, S., Dalton, H., Gibbons, K., Adderley, O., Chukwujindu, I., Jayasuriya, I., Sivanu, K., Borumand, M., Chick, G., Bridges, I., Tomlin, J., Mckenna, J., Nandra, N., Grieco, C., Quek, F. F., Mercer, R., Brankin-Frisby, T., Sattar, A., Aslam, A., Edelsten, E., Shafi, S., Kouli, T., Ford, V., Gurung, F., Fernandes, M., Deader, N., Ponniah, R., Jamieson, S., Davies, A., Taubwurcel, J., Aung, M. T., Desai, R., Begum, S., Jamadar, T., Kangatharan, A., Rzeszowski, B., Ho, C., Yap, S. H. K., Prendergast, M., Sethi, R., Duku, A., Lowe, C., Bray, J., Ghobrial, M., Nichita, V., Wagstaff, A., Rengasamy, E., Abu Hassan, F., Mahmood, H., Savill, N., Shah, S., Almeida, T., Edwards, A., Catchpole, B., Halford, Z., Carmichael, A., Alsusa, H., Boyd, M., Williams, J., Feyi-Waboso, J., Patel, M., Zeidan, Z., Bailey, E., Bapty, J., Brazkiewicz, M., Tremlett, A., Pringle, H., Mankal, S., Chung, W., Parry-Jones, E., Anderson, K., Mcforrester, A., Stanley, A., Hoather, A., Wise, H., Laid, I., Scriven, J., Braniste, A., Wilson, A., Le Blevec, L., Pakunwanich, N., Evans, N., Chong, H. L., White, C., Hunter, J., Haque, M., Vanalia, P., Murdoch, S., Choudhary, T., Mccann, A., Harun, A., Shah, H., Hunt, S., Shafiq, Y., Bickley-Morris, E., Emms, L., Dare, M., Akula, Y., Deliyannis, E., Mayes, F., Ellacott, M., Zagorac, Z., Farren, A., Manning, C., Hughed, C., Stewart, E. G., Lim, K. H., Chohan, N., Thaker, A., Thompson, B., Ahari, D., Burdekin, E., Okwu, U., Akintunde, A., Lhaf, F., Douthwaite, J., Govindan, R., Leelamanthep, S., Gull, E., Wright, F., Dundas, L., Mackdermott, N., Burchi-Khairy, T., Campbell, I., Walsh, J., Yeo, J. Y., Meehan, S., Banerjee, D., Fu, M., Kawka, M., Ali, T., Hussain, Z., Thomas, C., Ahmad, H., Moroney, J., Yick, C., Risquet, R., Ntuiabane, D., Shimato, M., Khan, M., Ilangovan, S., Vaselli, N. M., Smithers, R., Uhanowita Marage, R., Valnarov-Boulter, A., Kayran, J., Banerjee, M., Parekh-Hill, N., Hooper, A., Bowen, J., Jagdish, R., Mcquoid, C., Khan, N., O'Hare, R., Jeffery, S., Zahid, A., Elsworth, C., Walter, L., Dhillon, S., Rao, S., Anthony, A., Ashaye, A., Phillips, N., Faderani, R., Pengelly, S., Choi, S., Kwak, S. Y., Lau, Y. H. L., Bagheri, K., Ong, D. Y. C., Kerr, E., Falconer, K., Clancy, N., Douglas, S., Zhang, Y., Greenfield, F., Mutanga, I., Mcalinden, J., Willis, L., Adefolaju, A., Agarwal, H., Barter, R., Harris, G., Spencer, G., Lee, M. W., Vadiveloo, V. T., Herbert, G., Patel, R., Shah, M., El Falaha, S., Wong, C., Soare, C., Akram, J., Bozhkova, L., Ma, Y., Vo, U. G., Tan, H. W. N., Leto, L., Kamal, M. A., Hadzhieva, E., Krastev, P., Tonchev, P., Kokkinos, G., Pozotou, I., Sabbagh, D., Votava, J., St, F., Koliakos, N., Tsaparas, P., Zografos, G., Mantas, D., Tsourouflis, G., Fradelos, E., Trigiante, G., Labellarte, G., Resta, G., Capelli, G., D'Amore, A., Verlingieri, V., Campagnaro, T., Maffioli, A., Viscosi, F., De Lucia, C., Meneghini, S., Fancellu, A., Colella, M., Biondi, A., De Peppo, V., Pace, U., Albino, V., Gattulli, D., Piangerelli, A., Kalivaci, D., Sisto, G., Mazzola, M., Caneparo, A., Lunghi, E. G., Nespoli, L. C., Angrisani, M., Langone, A., Gelarda, E., Virgilio, E., Angelini, E., Fornasier, C., Asero, S., Filippone, E., Frongia, F., Calo, P. G., Panaccio, P., Ipponi, P., Gili, S., Braccio, B., Tiesi, V., Stolcers, K., Kokaine, L., Novikovs, V., Capel, L., Bastiaenen, V., Heijmans, H., Henriques, S., Gan, S. Z., Ramanayake, H., Nolan, M., Temperley, H., Ciofic, E., Pop, B. A., Kurtenkov, M., Jovanovic, M., Vician, M., Egea Arias, P., Beltran de Heredia, J., Labalde Martinez, M., De Santiago Alvarez, I., Alvarez-Gallego, M., Rodriguez Artigas, J. M., Dwidar, O., Korkmaz, H. K., Eray, I. C., Meric, S., Aydin, R., Cetin, B., Karaca, B. E., Kuyumcu, O. F., Yuksel, E., Uprak, T. K., Karabulut, K., Kavukcu, E., Mansor, A., Hackett, R., Zammit-Maempel, M., Sabaratnam, R., Maan, A., Ferarrio, I., Dixon, L., Halai, H., Sethi, S., Nelson, L., Grassam-Rowe, A., Krishnan, E., Deeny, D., Mckeever, M., George Pandeth, A., Dhavala, P., Sreenivasan, S., Sundaram Venkatesan, G., Zhu, L., Atiyah, Z., Gregory, J., Morey, T., Seymour, Z., Holdsworth, L., Abdelmahmoud, S., Bourhill, J., Bisheet, G., Shaw, J., Kulkarni, K., Kumarakulasingam, P., Pillay, S., Al-Habsi, R., Kungwengwe, G., Richards, J., Davoudi, K., Ibrahim, B., Tailor, B., Zayed, M., Chen, F., Bailey, S., Sheefat, S., Nawaz, G., Pawar, R., Marsh, S., Sam, Z. H., Roy Bentley, S., Simpson, C., Hughes, J., Lim, Y., Ooi, R., Toh, W. H., Mannion, P., Lovett, A., Kincius, A., Hussein, S., Kirby, E., Beckett, R. G., Salmon, J., Glynn, T., Choo, S. Y., Lyons, S., Browne, D., Ravindran, W., Ahmad, S., Zhu, X., Mcnulty, J., Mccarthy, L., Ng, J., Karmally, Z., Mcteir, K., Hanna, M., Tan, E., Namdeo, S., Schembri, R., and Pusey, E.
- Subjects
Adult ,Elective Surgical Procedure ,Aged ,Cohort Studies ,Drainage ,Elective Surgical Procedures ,Female ,Humans ,Postoperative Complications ,Prospective Studies ,Surgical Wound Infection ,Colorectal Surgery ,drain ,intrabdominal ,Adult, Aged, Cohort Studies, Colorectal Surgery, Drainage, Elective Surgical Procedures, Female, Humans, Postoperative Complications, Prospective Studies, Surgical Wound Infection ,Settore MED/18 ,Settore MED/18 - Chirurgia Generale ,Prospective Studie ,Surgery ,Postoperative Complication ,Cohort Studie ,drain, intrabdominal ,Human - Abstract
Background Many surgeons routinely place intraperitoneal drains after elective colorectal surgery. However, enhanced recovery after surgery guidelines recommend against their routine use owing to a lack of clear clinical benefit. This study aimed to describe international variation in intraperitoneal drain placement and the safety of this practice. Methods COMPASS (COMPlicAted intra-abdominal collectionS after colorectal Surgery) was a prospective, international, cohort study which enrolled consecutive adults undergoing elective colorectal surgery (February to March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included: rate and time to diagnosis of postoperative intraperitoneal collections; rate of surgical site infections (SSIs); time to discharge; and 30-day major postoperative complications (Clavien–Dindo grade at least III). After propensity score matching, multivariable logistic regression and Cox proportional hazards regression were used to estimate the independent association of the secondary outcomes with drain placement. Results Overall, 1805 patients from 22 countries were included (798 women, 44.2 per cent; median age 67.0 years). The drain insertion rate was 51.9 per cent (937 patients). After matching, drains were not associated with reduced rates (odds ratio (OR) 1.33, 95 per cent c.i. 0.79 to 2.23; P = 0.287) or earlier detection (hazard ratio (HR) 0.87, 0.33 to 2.31; P = 0.780) of collections. Although not associated with worse major postoperative complications (OR 1.09, 0.68 to 1.75; P = 0.709), drains were associated with delayed hospital discharge (HR 0.58, 0.52 to 0.66; P < 0.001) and an increased risk of SSIs (OR 2.47, 1.50 to 4.05; P < 0.001). Conclusion Intraperitoneal drain placement after elective colorectal surgery is not associated with earlier detection of postoperative collections, but prolongs hospital stay and increases SSI risk.
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- 2022
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5. SPLiCE Phase 1 Sustainable pathways to low carbon energy – Final report
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Tweed, J, Agnolucci, P, Austen, M, Fawcett, T, Hooper, T, Howard, D, Sims, L, Smithers, R, Stirling, A, and Whitaker, J
- Published
- 2022
6. Falco exilis Temminck 1830: proposed invalidation under the plenary powers in order to conserve Accipiter rufiventris Smith, 1830 (Aves). Z.N. (S.) 1956
- Author
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Clancey, P. A., Brooke, R K, Liversidge, R, Maclean, G, Smithers, R H B, Winterbottom, J M, and BioStor
- Published
- 1971
7. Study to support the evaluation of the EU Adaptation Strategy : Final report
- Author
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Smithers, R., Tweed, James, Phillips-Itty, Ruth, Nesbit, Martin, Illes, Andrea, Smith, Matthew, Eichler, L., Baroni, Laura, Klostermann, J.E.M., de Bruin, K., and Coninx, I.
- Subjects
Climate Resilience ,Klimaatbestendigheid ,Life Science ,Regional Development and Spatial Use ,Regionale Ontwikkeling en Ruimtegebruik - Published
- 2018
8. Corrigendum: a decision framework for considering climate change adaptation in biodiversity conservation planning
- Author
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Oliver, T. H., Smithers, R. J., Bailey, S., Walmsley, C. A., and Watts, K.
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ComputingMilieux_GENERAL ,ComputingMilieux_LEGALASPECTSOFCOMPUTING - Published
- 2015
9. Support to the development of EuAdaptStrat to Climate Change: Background report to the IA, Part I - Problem definition, policy context and assessment of policy options. Environment Agency Austria, Vienna
- Author
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MCCallum, S., Dworak, T., Prutsch, A., Kent, N., Mysiak, J., Bosello, F., Klostermann, J.E.M., Diugolecki, A., Williams, E., Konig, M., Leitner, M., Miller, K., Harley, M., Smithers, R., Berglund, M., Glas, N., Romanovska, L., van de Sandt, K., Bachschmidt, R., Völler, S., and Horrocks, L.
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Climate Resilience ,climatic change ,Klimaatbestendigheid ,klimaatverandering - Published
- 2013
10. Trophic level asynchrony in rates of phenological change for marine, freshwater and terrestrial environments
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Thackeray, S. J., Sparks, T. H., Frederiksen, M., Burthes, S., Bacon, P. J., Bell, J. R., Botham, M. C., Brereton, T. M., Bright, P. W., Carvalho, L., Clutton-Brock, T., Dawson, A., Edwards, M., Elliott, J. M., Harrington, R., Johns, D., Jones, I. D., Jones, J. T., Leech, D. I., Roy, D. B., Scott, W. A., Smith, M., Smithers, R. J., Winfield, I. J., and Wanless, S.
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Ecology ,sense organs ,biodiversity conservation ,skin and connective tissue diseases ,Environmental Sciences - Abstract
Recent changes in the seasonal timing (phenology) of familiar biological events have been one of the most conspicuous signs of climate change. However, the lack of a standardized approach to analysing change has hampered assessment of consistency in such changes among different taxa and trophic levels and across freshwater, terrestrial and marine environments. We present a standardized assessment of 25 532 rates of phenological change for 726 UK terrestrial, freshwater and marine taxa. The majority of spring and summer events have advanced, and more rapidly than previously documented. Such consistency is indicative of shared large scale drivers. Furthermore, average rates of change have accelerated in a way that is consistent with observed warming trends. Less coherent patterns in some groups of organisms point to the agency of more local scale processes and multiple drivers. For the first time we show a broad scale signal of differential phenological change among trophic levels; across environments advances in timing were slowest for secondary consumers, thus heightening the potential risk of temporal mismatch in key trophic interactions. If current patterns and rates of phenological change are indicative of future trends, future climate warming may exacerbate trophic mismatching, further disrupting the functioning, persistence and resilience of many ecosystems and having a major impact on ecosystem services.
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- 2010
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11. The identification of one hundred ecological questions of high policy relevance in the UK
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Sutherland, W. J., Armstrong Brown, S., Armsworth, P. R., Brereton, T., Brickland, J., Campbell, C. D., Chamberlain, Daniel Edward, Cooke, A. I., Dulvy, N. K., Dusic, N. R., Fitton, M., Freckleton, R. P., Godfray, H. C., Grout, N., Harvey, H. J., Hedley, C., Hopkins, J. J., Kift, N. B., Kirby, J., Kunin, W. E., Macdonald, D. W., Markee, B., Naura, M., Neale, A. R., Oliver, T., Osborn, D., Pullin, A. S., Shardlow, M. E. A., Showler, D. A., Smith, P. L., Smithers, R. J., Solandt, J. L., Spencer, J., Spray, C. J., Thomas, C. D., Thompson, J., Webb, S. E., Yalden, D. W., and Watkinson, A. R.
- Published
- 2006
12. England Biodiversity Strategy - towards adapation to climate change. Final report to Defra for contract CRO327
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Mitchell, R. J., Morecroft, M. D., Acreman, M., Crick, H. Q. P., Frost, M., Harley, M., Maclean, I. D. M., Mountford, O., Piper, J., Pontier, H., Rehfisch, M. M., Ross, L. C., Smithers, R. J., Stott, A., Walmsley, C. A., Watts, O., Wilson, E., Mitchell, R. J., Morecroft, M. D., Acreman, M., Crick, H. Q. P., Frost, M., Harley, M., Maclean, I. D. M., Mountford, O., Piper, J., Pontier, H., Rehfisch, M. M., Ross, L. C., Smithers, R. J., Stott, A., Walmsley, C. A., Watts, O., and Wilson, E.
- Abstract
1. The evidence that the Earth’s climate is changing as a consequence of human activity is strong and accepted by the overwhelming majority of scientific opinion. The changing climate is beginning to have an impact on English ecosystems and this impact is expected to increase and accelerate in future, threatening the conservation of biodiversity. 2. The England Biodiversity Strategy (EBS) “Working with the Grain of Nature” aims to ensure that biodiversity considerations become embedded in all the main sectors of economic activity that have an impact on or relationship with delivery of biodiversity objectives, both public and private. 3. This report reviews the scientific evidence and summarises the potential impacts of climate change on the biodiversity of England within each of the sectors of the EBS: Agriculture, Water and Wetlands, Woodland and Forestry, Coastal and Marine, Towns and Cities. It includes direct impacts and indirect ones resulting from human responses to climate change. It gives a brief overview of the main non-climatic pressures on biodiversity and their possible interactions with climate change. Principles and measures for adapting biodiversity policy and management to climate change are presented.
- Published
- 2007
13. The identification of 100 ecological questions of high policy relevance in the UK
- Author
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Sutherland, W. J., Armstrong-Brown, S., Armsworth, P. R., Brereton, T., Brickland, J., Campbell, C. D., Chamberlain, D. E., Cooke, A. I., Dulvy, N. K., Dusic, N. R., Fitton, M., Freckleton, R. P., Godfray, C. J., Grout, N., Harvey, H. J., Hedley, C., Hopkins, J. J., Kift, N. B., Kirby, J., Kunin, W. E., MacDonald, D. W., Marker, B., Naura, M., Neale, R., Oliver, T., Osborn, D., Pullin, A. S., Shardlow, M. E. A., Showler, D. A., Smith, P. L., Smithers, R. J., Solandt, J. C., Spencer, J., Spray, C. J., Thomas, C. D., Thompson, J., Webb, S. E., Yalden, D. W., Watkinson, A. R., Sutherland, W. J., Armstrong-Brown, S., Armsworth, P. R., Brereton, T., Brickland, J., Campbell, C. D., Chamberlain, D. E., Cooke, A. I., Dulvy, N. K., Dusic, N. R., Fitton, M., Freckleton, R. P., Godfray, C. J., Grout, N., Harvey, H. J., Hedley, C., Hopkins, J. J., Kift, N. B., Kirby, J., Kunin, W. E., MacDonald, D. W., Marker, B., Naura, M., Neale, R., Oliver, T., Osborn, D., Pullin, A. S., Shardlow, M. E. A., Showler, D. A., Smith, P. L., Smithers, R. J., Solandt, J. C., Spencer, J., Spray, C. J., Thomas, C. D., Thompson, J., Webb, S. E., Yalden, D. W., and Watkinson, A. R.
- Abstract
1. Evidence-based policy requires researchers to provide the answers to ecological questions that are of interest to policy makers. To find out what those questions are in the UK, representatives from 28 organizations involved in policy, together with scientists from 10 academic institutions, were asked to generate a list of questions from their organizations. 2. During a 2-day workshop the initial list of 1003 questions generated from consulting at least 654 policy makers and academics was used as a basis for generating a short list of 100 questions of significant policy relevance. Short-listing was decided on the basis of the preferences of the representatives from the policy-led organizations. 3. The areas covered included most major issues of environmental concern in the UK, including agriculture, marine fisheries, climate change, ecosystem function and land management. 4. The most striking outcome was the preference for general questions rather than narrow ones. The reason is that policy is driven by broad issues rather than specific ones. In contrast, scientists are frequently best equipped to answer specific questions. This means that it may be necessary to extract the underpinning specific question before researchers can proceed. 5. Synthesis and applications. Greater communication between policy makers and scientists is required in order to ensure that applied ecologists are dealing with issues in a way that can feed into policy. It is particularly important that applied ecologists emphasize the generic value of their work wherever possible.
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- 2006
14. A participatory process for identifying and prioritizing policy-relevant research questions in natural resource management: a case study from the UK forestry sector
- Author
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Petrokofsky, G., primary, Brown, N. D., additional, Hemery, G. E., additional, Woodward, S., additional, Wilson, E., additional, Weatherall, A., additional, Stokes, V., additional, Smithers, R. J., additional, Sangster, M., additional, Russell, K., additional, Pullin, A. S., additional, Price, C., additional, Morecroft, M., additional, Malins, M., additional, Lawrence, A., additional, Kirby, K. J., additional, Godbold, D., additional, Charman, E., additional, Boshier, D., additional, Bosbeer, S., additional, and Arnold, J. E. M., additional
- Published
- 2010
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15. Climate Change and Woodland Biodiversity
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Collinson, N. H., primary and Smithers, R. J., additional
- Published
- 2002
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16. Is spring getting earlier?
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Sparks, T. H., primary and Smithers, R. J., additional
- Published
- 2002
- Full Text
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17. In Memoriam
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Smithers, R B, primary
- Published
- 1994
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18. ChemInform Abstract: The Electrophilic Substitution of Allylsilanes and Vinylsilanes
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FLEMING, I., primary, DUNOGUES, J., additional, and SMITHERS, R., additional
- Published
- 1990
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19. NOTES ON THE AVIFAUNA OF THE EASTERN SECTOR OF THE GREAT MAKARIKARI LAKE, BECHUANALAND PROTECTORATE.
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Smithers, R. and Paterson, M.
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- 1959
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20. SHORT NOTES.
- Author
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Winterbottom, J. M., Oatley, T., Haydock, E. L., Brooke, R. K., Smithers, R., Badenhorst, M., and Quinton, W. F.
- Published
- 1956
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21. SOME INTERESTING RHODESIAN AND BECHUANALAND RECORDS, III.
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Smithers, R. H. N.
- Published
- 1956
- Full Text
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22. Tellurium isotope fractionation study.
- Author
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Smithers, R. M. and Krouse, H. R.
- Published
- 1968
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23. Letter from Smithers to Keller (1969)
- Author
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Smithers, R. Brinkley
- Abstract
Invitation from Brinkley Smithers to join Honorary Committee and banquet to pay tribute to industry leaders for their programs to control alcoholism and problem drinking. From the Mark Keller Papers.
- Published
- 1969
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24. Letter from Brinkley Smithers to E. M. Jellinek (1957)
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Smithers, R. Brinkley
- Abstract
A letter on supporting alcohol research and E.M. Jellinek from the Christopher D. Smithers Foundation, the only organization operating in the United States "in the field of alcoholism."
- Published
- 1957
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25. The blurring of the seasons: A focus on autumn phenology
- Author
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Tim Sparks and Smithers, R.
26. ChemInform Abstract: A ONE POT E-SELECTIVE ROUTE TO UNSATURATED ESTERS USING LITHIUM METHOXYACETYLIDE FROM A NON-ACETYLENIC PRECURSOR
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SMITHERS, R. H., primary
- Published
- 1985
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27. ChemInform Abstract: DESICCANT EFFICIENCY IN SOLVENT AND REAGENT DRYING. 5. AMINES
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BURFIELD, D. R., primary, SMITHERS, R. H., additional, and TAN, A. S. C., additional
- Published
- 1981
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28. ChemInform Abstract: DESICCANT EFFICIENCY IN SOLVENT AND REAGENT DRYING. 7. ALCOHOLS
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BURFIELD, D. R., primary and SMITHERS, R. H., additional
- Published
- 1983
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29. ChemInform Abstract: DESICCANT EFFICIENCY IN SOLVENT DRYING. A REAPPRAISAL BY APPLICATION OF A NOVEL METHOD FOR SOLVENT WATER ASSAY
- Author
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BURFIELD, D. R., primary, LEE, K. H., additional, and SMITHERS, R. H., additional
- Published
- 1978
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30. ChemInform Abstract: LITHIUM ALKOXYACETYLENIDES: DIRECT ACCESS BY A NEW AND CONVENIENT GENERAL ROUTE
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SMITHERS, R. H., primary
- Published
- 1985
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31. ChemInform Abstract: EXTERNAL ACTIVATION OF EPOXIDES BY POLARIZING GROUPS BORNE BY THE NUCLEOPHILE
- Author
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BURFIELD, D. R., primary, KHOO, T.-K., additional, and SMITHERS, R. H., additional
- Published
- 1981
- Full Text
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32. ChemInform Abstract: A NEW STEREOSELECTIVE ROUTE TO TRISUBSTITUTED BROMO OLEFINS UTILIZING α-BROMOALKYLIDES PRODUCED BY HALOGEN-METAL EXCHANGE
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SMITHERS, R. H., primary
- Published
- 1979
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33. ChemInform Abstract: DESICCANT EFFICIENCY IN SOLVENT DRYING. 3. DIPOLAR APROTIC SOLVENTS
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BURFIELD, D. R., primary and SMITHERS, R. H., additional
- Published
- 1979
- Full Text
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34. ChemInform Abstract: REACTIONS OF A MONO- AND A TRI-SUBSTITUTED EPOXIDE WITH SOME SIMPLE AND β-SUBSTITUTED PRIMARY AMINES, NOVEL EXAMPLES OF ELECTROPHILIC ANCHIMERIC ASSISTANCE
- Author
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BURFIELD, D. R., primary, GAN, S., additional, and SMITHERS, R. H., additional
- Published
- 1977
- Full Text
- View/download PDF
35. ChemInform Abstract: Bis((trimethylsilyl)ethynyl) Ether: A Moderately Stable C4H2O Derivative.
- Author
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OOI, I.-H., primary and SMITHERS, R. H., additional
- Published
- 1989
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36. ChemInform Abstract: 1‐BROMO‐2‐METHOXYVINYLLITHIUM: A USEFUL BROMOACETALDEHYDE ANION EQUIVALENT FROM 1,1‐DIBROMO‐2‐METHOXYETHENE
- Author
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SMITHERS, R. H., primary
- Published
- 1983
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37. ChemInform Abstract: Effect of a β-Silyl Group on the Regiochemistry of Enolization of Ketones.
- Author
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ENGEL, W., primary, FLEMING, I., additional, and SMITHERS, R. H., additional
- Published
- 1987
- Full Text
- View/download PDF
38. ChemInform Abstract: α-BROMOALKYLIDES IN TRISUBSTITUTED OLEFIN SYNTHESIS. REGIOSPECIFIC ENTRY TO 4-BROMO-1,4-DIENES
- Author
-
SMITHERS, R. H., primary
- Published
- 1980
- Full Text
- View/download PDF
39. ChemInform Abstract: DEBROMIERUNG VON ALPHA,ALPHA′-DIBROM-KETONEN MIT EINEM ZINK-KUPFER-PAAR IN METHANOL, BLDG. VON ALPHA-METHOXY-KETONEN ALS KRITERIUM FUER KATIONISCHE 2-OXYALLYL-ZWISCHENSTUFEN
- Author
-
HOFFMANN, H. M. R., primary, NOUR, T. A., additional, and SMITHERS, R. H., additional
- Published
- 1972
- Full Text
- View/download PDF
40. ChemInform Abstract: ISOBULLATENON UND EIN DEMETHYLIERTES ANALOGON, EIN NEUER WEG ZU 3(2H)‐FURANONEN
- Author
-
BARROW, M.‐A., primary, RICHARDS, A. C., additional, SMITHERS, R. H., additional, and HOFFMANN, H. M. R., additional
- Published
- 1972
- Full Text
- View/download PDF
41. Falco exilis Temminck 1830: proposed invalidation under the plenary powers in order to conserve Accipiter rufiventris Smith, 1830 (Aves). Z.N. (S.) 1956
- Author
-
Clancey, P. A., primary, Brooke, R K, additional, Liversidge, R, additional, Maclean, G, additional, Smithers, R H B, additional, and Winterbottom, J M, additional
- Published
- 1971
- Full Text
- View/download PDF
42. Debromination of α,α′-dibromo-ketones with a zinc–copper couple in methanol. Formation of α-methoxy-ketones as a criterion for the intervention of 2-oxyallyl cations
- Author
-
Hoffmann, H. M. R., primary, Nour, T. A., additional, and Smithers, R. H., additional
- Published
- 1972
- Full Text
- View/download PDF
43. THE TEITA FALCON FALCO FASCIINUCHA REICHENOW & NEUMANN AT THE VICTORIA FALLS
- Author
-
Benson, C. W., primary and Smithers, R. H. N., additional
- Published
- 1958
- Full Text
- View/download PDF
44. ARTICLE UNSPOILED
- Author
-
Smithers, R Brinkley, primary
- Published
- 1971
- Full Text
- View/download PDF
45. Stereospecific generation of 2-oxyallylic cations from two new sources. Steric course of cycloaddition to conjugated dienes
- Author
-
Hoffmann, H. M. R., primary, Clemens, K. E., additional, and Smithers, R. H., additional
- Published
- 1972
- Full Text
- View/download PDF
46. ChemInform Abstract: ALLENOXIDE 1. MITT. 3-ISOPROPYLIDEN-(2,2)-DIMETHYL-OXIRAN (TETRAMETHYLALLENOXID)
- Author
-
HOFFMANN, H. M. R., primary and SMITHERS, R. H., additional
- Published
- 1970
- Full Text
- View/download PDF
47. THE DOCTOR IN THE WITNESS BOX
- Author
-
Smithers, R. A., primary
- Published
- 1954
- Full Text
- View/download PDF
48. 3‐Isopropyliden‐2,2‐dimethyloxiran (Tetramethylallenoxid)
- Author
-
Hoffmann, H. M. R., primary and Smithers, R. H., additional
- Published
- 1970
- Full Text
- View/download PDF
49. ChemInform Abstract: STEREOSPEZIFISCHE ERZEUGUNG VON 2-OXY-ALLYLKATIONEN AUS ZWEI NEUEN QUELLEN, STERISCHER VERLAUF DER CYCLOADDITION AN KONJUGIERTE DIENE
- Author
-
HOFFMANN, H. M. R., primary, CLEMENS, K. E., additional, and SMITHERS, R. H., additional
- Published
- 1972
- Full Text
- View/download PDF
50. The poison spline system
- Author
-
Smithers, R
- Published
- 1960
- Full Text
- View/download PDF
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