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1. Does the neighborhood food environment contribute to ethnic inequalities in fast-food intake? findings from the ORiEL study

Author

Shareck, Martine, Benmarhnia, Tarik, Berger, Nicolas, Smith, Neil R, Lewis, Daniel, and Cummins, Steven

Subjects
Public Health, Health Sciences, Prevention, Nutrition, Aetiology, 2.3 Psychological, social and economic factors, Reduced Inequalities, Adolescent, Ethnicity, Fast-food, Food environment, Foodscape, Inequality, Pathway, Youth, Public Health and Health Services, Epidemiology, Health services and systems, Public health
Abstract

The neighborhood food environment may contribute to ethnic inequalities in diet. Using data from 1389 participants in the Olympic Regeneration in East London (UK) study we assessed whether ethnic inequalities in neighborhood availability of fast-food restaurants mediated and/or modified ethnic inequalities in fast-food intake in 13-15 year-old adolescents. We compared the proportion of high fast-food consumers across "White UK", "Black", and "South Asian" ethnic categories. We used Poisson regression with robust standard errors to assess direct and indirect effects (mediation analysis) and risk ratios of high fast-food intake by ethnic category and fast-food restaurant availability level (effect measure modification analysis). There were ethnic inequalities in high fast-food intake, with risk ratios in adolescents of Black and South Asian background of 1.53 (95% CI: 1.25, 1.87) and 1.71 (95% CI: 1.41, 2.07) respectively compared to White UK participants. We found no evidence of a mediating effect by fast-food restaurant availability, but found some evidence of effect measure modification: ethnic inequalities in fast-food intake were largest in neighborhoods lacking fast-food restaurants, and narrowed as availability increased. Future research should explore why ethnic minorities are more likely to be high fast-food consumers than the majority ethnic group, especially when fast-food restaurant availability is lowest.

Published
2019

3. Data from High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial

Author

Pearson, Alex, primary, Smyth, Elizabeth, primary, Babina, Irina S., primary, Herrera-Abreu, Maria Teresa, primary, Tarazona, Noelia, primary, Peckitt, Clare, primary, Kilgour, Elaine, primary, Smith, Neil R., primary, Geh, Catherine, primary, Rooney, Claire, primary, Cutts, Ros, primary, Campbell, James, primary, Ning, Jian, primary, Fenwick, Kerry, primary, Swain, Amanda, primary, Brown, Gina, primary, Chua, Sue, primary, Thomas, Anne, primary, Johnston, Stephen R.D., primary, Ajaz, Mazhar, primary, Sumpter, Katherine, primary, Gillbanks, Angela, primary, Watkins, David, primary, Chau, Ian, primary, Popat, Sanjay, primary, Cunningham, David, primary, and Turner, Nicholas C., primary

Published
2023
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4. Supplementary Methods, Figure Legend from MEDI0639: A Novel Therapeutic Antibody Targeting Dll4 Modulates Endothelial Cell Function and Angiogenesis In Vivo

Author

Jenkins, David W., primary, Ross, Sarah, primary, Veldman-Jones, Margaret, primary, Foltz, Ian N., primary, Clavette, Brandon C., primary, Manchulenko, Kathy, primary, Eberlein, Cath, primary, Kendrew, Jane, primary, Petteruti, Philip, primary, Cho, Song, primary, Damschroder, Melissa, primary, Peng, Li, primary, Baker, Dawn, primary, Smith, Neil R., primary, Weir, Hazel M., primary, Blakey, David C., primary, Bedian, Vahe, primary, and Barry, Simon T., primary

Published
2023
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5. Supplementary Figure 1 from High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial

Author

Pearson, Alex, primary, Smyth, Elizabeth, primary, Babina, Irina S., primary, Herrera-Abreu, Maria Teresa, primary, Tarazona, Noelia, primary, Peckitt, Clare, primary, Kilgour, Elaine, primary, Smith, Neil R., primary, Geh, Catherine, primary, Rooney, Claire, primary, Cutts, Ros, primary, Campbell, James, primary, Ning, Jian, primary, Fenwick, Kerry, primary, Swain, Amanda, primary, Brown, Gina, primary, Chua, Sue, primary, Thomas, Anne, primary, Johnston, Stephen R.D., primary, Ajaz, Mazhar, primary, Sumpter, Katherine, primary, Gillbanks, Angela, primary, Watkins, David, primary, Chau, Ian, primary, Popat, Sanjay, primary, Cunningham, David, primary, and Turner, Nicholas C., primary

Published
2023
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6. Supplementary Figure 6 from High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial

Author

Pearson, Alex, primary, Smyth, Elizabeth, primary, Babina, Irina S., primary, Herrera-Abreu, Maria Teresa, primary, Tarazona, Noelia, primary, Peckitt, Clare, primary, Kilgour, Elaine, primary, Smith, Neil R., primary, Geh, Catherine, primary, Rooney, Claire, primary, Cutts, Ros, primary, Campbell, James, primary, Ning, Jian, primary, Fenwick, Kerry, primary, Swain, Amanda, primary, Brown, Gina, primary, Chua, Sue, primary, Thomas, Anne, primary, Johnston, Stephen R.D., primary, Ajaz, Mazhar, primary, Sumpter, Katherine, primary, Gillbanks, Angela, primary, Watkins, David, primary, Chau, Ian, primary, Popat, Sanjay, primary, Cunningham, David, primary, and Turner, Nicholas C., primary

Published
2023
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7. Supplementary Figure Legends, Tables 1 - 3 from High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial

Author

Pearson, Alex, primary, Smyth, Elizabeth, primary, Babina, Irina S., primary, Herrera-Abreu, Maria Teresa, primary, Tarazona, Noelia, primary, Peckitt, Clare, primary, Kilgour, Elaine, primary, Smith, Neil R., primary, Geh, Catherine, primary, Rooney, Claire, primary, Cutts, Ros, primary, Campbell, James, primary, Ning, Jian, primary, Fenwick, Kerry, primary, Swain, Amanda, primary, Brown, Gina, primary, Chua, Sue, primary, Thomas, Anne, primary, Johnston, Stephen R.D., primary, Ajaz, Mazhar, primary, Sumpter, Katherine, primary, Gillbanks, Angela, primary, Watkins, David, primary, Chau, Ian, primary, Popat, Sanjay, primary, Cunningham, David, primary, and Turner, Nicholas C., primary

Published
2023
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8. Supplementary Figure 2 from High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial

Author

Pearson, Alex, primary, Smyth, Elizabeth, primary, Babina, Irina S., primary, Herrera-Abreu, Maria Teresa, primary, Tarazona, Noelia, primary, Peckitt, Clare, primary, Kilgour, Elaine, primary, Smith, Neil R., primary, Geh, Catherine, primary, Rooney, Claire, primary, Cutts, Ros, primary, Campbell, James, primary, Ning, Jian, primary, Fenwick, Kerry, primary, Swain, Amanda, primary, Brown, Gina, primary, Chua, Sue, primary, Thomas, Anne, primary, Johnston, Stephen R.D., primary, Ajaz, Mazhar, primary, Sumpter, Katherine, primary, Gillbanks, Angela, primary, Watkins, David, primary, Chau, Ian, primary, Popat, Sanjay, primary, Cunningham, David, primary, and Turner, Nicholas C., primary

Published
2023
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9. Supplementary Figure 3 from High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial

Author

Pearson, Alex, primary, Smyth, Elizabeth, primary, Babina, Irina S., primary, Herrera-Abreu, Maria Teresa, primary, Tarazona, Noelia, primary, Peckitt, Clare, primary, Kilgour, Elaine, primary, Smith, Neil R., primary, Geh, Catherine, primary, Rooney, Claire, primary, Cutts, Ros, primary, Campbell, James, primary, Ning, Jian, primary, Fenwick, Kerry, primary, Swain, Amanda, primary, Brown, Gina, primary, Chua, Sue, primary, Thomas, Anne, primary, Johnston, Stephen R.D., primary, Ajaz, Mazhar, primary, Sumpter, Katherine, primary, Gillbanks, Angela, primary, Watkins, David, primary, Chau, Ian, primary, Popat, Sanjay, primary, Cunningham, David, primary, and Turner, Nicholas C., primary

Published
2023
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10. Supplementary Figure 5 from High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial

Author

Pearson, Alex, primary, Smyth, Elizabeth, primary, Babina, Irina S., primary, Herrera-Abreu, Maria Teresa, primary, Tarazona, Noelia, primary, Peckitt, Clare, primary, Kilgour, Elaine, primary, Smith, Neil R., primary, Geh, Catherine, primary, Rooney, Claire, primary, Cutts, Ros, primary, Campbell, James, primary, Ning, Jian, primary, Fenwick, Kerry, primary, Swain, Amanda, primary, Brown, Gina, primary, Chua, Sue, primary, Thomas, Anne, primary, Johnston, Stephen R.D., primary, Ajaz, Mazhar, primary, Sumpter, Katherine, primary, Gillbanks, Angela, primary, Watkins, David, primary, Chau, Ian, primary, Popat, Sanjay, primary, Cunningham, David, primary, and Turner, Nicholas C., primary

Published
2023
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11. Supplementary Figure 4 from High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial

Author

Pearson, Alex, primary, Smyth, Elizabeth, primary, Babina, Irina S., primary, Herrera-Abreu, Maria Teresa, primary, Tarazona, Noelia, primary, Peckitt, Clare, primary, Kilgour, Elaine, primary, Smith, Neil R., primary, Geh, Catherine, primary, Rooney, Claire, primary, Cutts, Ros, primary, Campbell, James, primary, Ning, Jian, primary, Fenwick, Kerry, primary, Swain, Amanda, primary, Brown, Gina, primary, Chua, Sue, primary, Thomas, Anne, primary, Johnston, Stephen R.D., primary, Ajaz, Mazhar, primary, Sumpter, Katherine, primary, Gillbanks, Angela, primary, Watkins, David, primary, Chau, Ian, primary, Popat, Sanjay, primary, Cunningham, David, primary, and Turner, Nicholas C., primary

Published
2023
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12. Data from Vascular Endothelial Growth Factor Receptors VEGFR-2 and VEGFR-3 Are Localized Primarily to the Vasculature in Human Primary Solid Cancers

Author

Smith, Neil R., primary, Baker, Dawn, primary, James, Neil H., primary, Ratcliffe, Kirsty, primary, Jenkins, Martin, primary, Ashton, Susan E., primary, Sproat, Graham, primary, Swann, Ruth, primary, Gray, Neil, primary, Ryan, Anderson, primary, Jürgensmeier, Juliane M., primary, and Womack, Chris, primary

Published
2023
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15. Supplementary File 2 from A Phase Ib Open-Label Multicenter Study of AZD4547 in Patients with Advanced Squamous Cell Lung Cancers

Author

Paik, Paul K., primary, Shen, Ronglai, primary, Berger, Michael F., primary, Ferry, David, primary, Soria, Jean-Charles, primary, Mathewson, Alastair, primary, Rooney, Claire, primary, Smith, Neil R., primary, Cullberg, Marie, primary, Kilgour, Elaine, primary, Landers, Donal, primary, Frewer, Paul, primary, Brooks, Nigel, primary, and André, Fabrice, primary

Published
2023
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16. Supplementary File 1 from A Phase Ib Open-Label Multicenter Study of AZD4547 in Patients with Advanced Squamous Cell Lung Cancers

Author

Paik, Paul K., primary, Shen, Ronglai, primary, Berger, Michael F., primary, Ferry, David, primary, Soria, Jean-Charles, primary, Mathewson, Alastair, primary, Rooney, Claire, primary, Smith, Neil R., primary, Cullberg, Marie, primary, Kilgour, Elaine, primary, Landers, Donal, primary, Frewer, Paul, primary, Brooks, Nigel, primary, and André, Fabrice, primary

Published
2023
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17. Supplementary File 5 from A Phase Ib Open-Label Multicenter Study of AZD4547 in Patients with Advanced Squamous Cell Lung Cancers

Author

Paik, Paul K., primary, Shen, Ronglai, primary, Berger, Michael F., primary, Ferry, David, primary, Soria, Jean-Charles, primary, Mathewson, Alastair, primary, Rooney, Claire, primary, Smith, Neil R., primary, Cullberg, Marie, primary, Kilgour, Elaine, primary, Landers, Donal, primary, Frewer, Paul, primary, Brooks, Nigel, primary, and André, Fabrice, primary

Published
2023
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19. Supplementary File 3 from A Phase Ib Open-Label Multicenter Study of AZD4547 in Patients with Advanced Squamous Cell Lung Cancers

Author

Paik, Paul K., primary, Shen, Ronglai, primary, Berger, Michael F., primary, Ferry, David, primary, Soria, Jean-Charles, primary, Mathewson, Alastair, primary, Rooney, Claire, primary, Smith, Neil R., primary, Cullberg, Marie, primary, Kilgour, Elaine, primary, Landers, Donal, primary, Frewer, Paul, primary, Brooks, Nigel, primary, and André, Fabrice, primary

Published
2023
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20. Supplementary File 6 from A Phase Ib Open-Label Multicenter Study of AZD4547 in Patients with Advanced Squamous Cell Lung Cancers

Author

Paik, Paul K., primary, Shen, Ronglai, primary, Berger, Michael F., primary, Ferry, David, primary, Soria, Jean-Charles, primary, Mathewson, Alastair, primary, Rooney, Claire, primary, Smith, Neil R., primary, Cullberg, Marie, primary, Kilgour, Elaine, primary, Landers, Donal, primary, Frewer, Paul, primary, Brooks, Nigel, primary, and André, Fabrice, primary

Published
2023
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23. Supplementary Data from Vascular Endothelial Growth Factor Receptors VEGFR-2 and VEGFR-3 Are Localized Primarily to the Vasculature in Human Primary Solid Cancers

Author

Smith, Neil R., primary, Baker, Dawn, primary, James, Neil H., primary, Ratcliffe, Kirsty, primary, Jenkins, Martin, primary, Ashton, Susan E., primary, Sproat, Graham, primary, Swann, Ruth, primary, Gray, Neil, primary, Ryan, Anderson, primary, Jürgensmeier, Juliane M., primary, and Womack, Chris, primary

Published
2023
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25. Supplementary File 4 from A Phase Ib Open-Label Multicenter Study of AZD4547 in Patients with Advanced Squamous Cell Lung Cancers

Author

Paik, Paul K., primary, Shen, Ronglai, primary, Berger, Michael F., primary, Ferry, David, primary, Soria, Jean-Charles, primary, Mathewson, Alastair, primary, Rooney, Claire, primary, Smith, Neil R., primary, Cullberg, Marie, primary, Kilgour, Elaine, primary, Landers, Donal, primary, Frewer, Paul, primary, Brooks, Nigel, primary, and André, Fabrice, primary

Published
2023
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33. Abstract 5737: Precision oncology driven real world clinical genomics data mining of MET alterations, TMB, and PDL-1 to empower indication agnostic patient enrollment and combination strategies

Author

Feng, Zheng, primary, Pignon, Jean-Christophe, additional, Sharaf, Radwa, additional, Romanov, Natalie, additional, Doudement, Julien, additional, Albacker, Lee A., additional, Kurata, Noriaki, additional, Smith, Neil R., additional, Matsushita, Nobutoshi, additional, and Scheuenpflug, Juergen, additional

Published
2022
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39. Stay home : affecting lives

Author

Kolbas, Valerija, Taylor, Isabel, Smith, Neil R., Kolbas, Valerija, Taylor, Isabel, and Smith, Neil R.

Published
2021

47. The Olympic Regeneration in East London (ORiEL) study: protocol for a prospective controlled quasi-experiment to evaluate the impact of urban regeneration on young people and their families

Author

Smith, Neil R, Clark, Charlotte, Fahy, Amanda E, Tharmaratnam, Vanathi, Lewis, Daniel J, Thompson, Claire, Renton, Adrian, Moore, Derek G, Bhui, Kamaldeep S, Taylor, Stephanie JC, Eldridge, Sandra, Petticrew, Mark, Greenhalgh, Tricia, Stansfeld, Stephen A, and Cummins, Steven

Subjects
education
Abstract

INTRODUCTION: Recent systematic reviews suggest that there is a dearth of evidence on the effectiveness of large-scale urban regeneration programmes in improving health and well-being and alleviating health inequalities. The development of the Olympic Park in Stratford for the London 2012 Olympic and Paralympic Games provides the opportunity to take advantage of a natural experiment to examine the impact of large-scale urban regeneration on the health and well-being of young people and their families. DESIGN AND METHODS: A prospective school-based survey of adolescents (11-12 years) with parent data collected through face-to-face interviews at home. Adolescents will be recruited from six randomly selected schools in an area receiving large-scale urban regeneration (London Borough of Newham) and compared with adolescents in 18 schools in three comparison areas with no equivalent regeneration (London Boroughs of Tower Hamlets, Hackney and Barking and Dagenham). Baseline data will be completed prior to the start of the London Olympics (July 2012) with follow-up at 6 and 18 months postintervention. Primary outcomes are: pre-post change in adolescent and parent mental health and well-being, physical activity and parental employment status. Secondary outcomes include: pre-post change in social cohesion, smoking, alcohol use, diet and body mass index. The study will account for individual and environmental contextual effects in evaluating changes to identified outcomes. A nested longitudinal qualitative study will explore families' experiences of regeneration in order to unpack the process by which regeneration impacts on health and well-being. ETHICS AND DISSEMINATION: The study has approval from Queen Mary University of London Ethics Committee (QMREC2011/40), the Association of Directors of Children's Services (RGE110927) and the London Boroughs Research Governance Framework (CERGF113). Fieldworkers have had advanced Criminal Records Bureau clearance. Findings will be disseminated through peer-reviewed publications, national and international conferences, through participating schools and the study website (http://www.orielproject.co.uk).

Published
2016

48. A Phase Ib Open-Label Multicenter Study of AZD4547 in Patients with Advanced Squamous Cell Lung Cancers

Author

Paik, Paul K., primary, Shen, Ronglai, additional, Berger, Michael F., additional, Ferry, David, additional, Soria, Jean-Charles, additional, Mathewson, Alastair, additional, Rooney, Claire, additional, Smith, Neil R., additional, Cullberg, Marie, additional, Kilgour, Elaine, additional, Landers, Donal, additional, Frewer, Paul, additional, Brooks, Nigel, additional, and André, Fabrice, additional

Published
2017
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50. High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial

Author

Pearson, Alex, primary, Smyth, Elizabeth, additional, Babina, Irina S., additional, Herrera-Abreu, Maria Teresa, additional, Tarazona, Noelia, additional, Peckitt, Clare, additional, Kilgour, Elaine, additional, Smith, Neil R., additional, Geh, Catherine, additional, Rooney, Claire, additional, Cutts, Ros, additional, Campbell, James, additional, Ning, Jian, additional, Fenwick, Kerry, additional, Swain, Amanda, additional, Brown, Gina, additional, Chua, Sue, additional, Thomas, Anne, additional, Johnston, Stephen R.D., additional, Ajaz, Mazhar, additional, Sumpter, Katherine, additional, Gillbanks, Angela, additional, Watkins, David, additional, Chau, Ian, additional, Popat, Sanjay, additional, Cunningham, David, additional, and Turner, Nicholas C., additional

Published
2016
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