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3,127 results on '"Smith, Kathryn"'

6. A global overview of marine heatwaves in a changing climate

Author

Capotondi, Antonietta, Rodrigues, Regina R., Sen Gupta, Alex, Benthuysen, Jessica A., Deser, Clara, Frölicher, Thomas L., Lovenduski, Nicole S., Amaya, Dillon J., Le Grix, Natacha, Xu, Tongtong, Hermes, Juliet, Holbrook, Neil J., Martinez-Villalobos, Cristian, Masina, Simona, Roxy, Mathew Koll, Schaeffer, Amandine, Schlegel, Robert W., Smith, Kathryn E., and Wang, Chunzai

Published
2024
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9. Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation

Author

Rödström, Karin E. J., Cloake, Alexander, Sörmann, Janina, Baronina, Agnese, Smith, Kathryn H. M., Pike, Ashley C. W., Ang, Jackie, Proks, Peter, Schewe, Marcus, Holland-Kaye, Ingelise, Bushell, Simon R., Elliott, Jenna, Pardon, Els, Baukrowitz, Thomas, Owens, Raymond J., Newstead, Simon, Steyaert, Jan, Carpenter, Elisabeth P., and Tucker, Stephen J.

Published
2024
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11. When eating disorder attitudes and cognitions persist after weight restoration: An exploratory examination of non‐cognitive responders to family‐based treatment for adolescent anorexia nervosa

Author

Egbert, Amy H, Gorrell, Sasha, Smith, Kathryn E, Goldschmidt, Andrea B, Hughes, Elizabeth K, Sawyer, Susan M, Yeo, Michelle, Lock, James, and Le Grange, Daniel

Subjects
Paediatrics, Clinical and Health Psychology, Biomedical and Clinical Sciences, Psychology, Mind and Body, Pediatric, Behavioral and Social Science, Anorexia, Nutrition, Eating Disorders, Clinical Research, Clinical Trials and Supportive Activities, Mental Health, Mental health, Female, Humans, Adolescent, Male, Body Weight, Anorexia Nervosa, Family Therapy, Weight Gain, Treatment Outcome, Cognition, adolescence, anorexia nervosa, cognitive recovery, family-based treatment, remission, weight gain, Clinical Sciences, Clinical Psychology, Clinical sciences, Nutrition and dietetics, Clinical and health psychology
Abstract

ObjectiveFamily-based treatment (FBT) is a well-established intervention for adolescent anorexia nervosa (AN). Although FBT is efficacious in promoting weight gain and improvements in psychological symptoms, for some adolescents, cognitive/attitudinal recovery lags behind weight gain. This study conducted an exploratory post hoc analysis of outcomes of adolescents who achieved weight gain by the end of FBT but continued to experience elevated psychological symptoms post-treatment.MethodsData were drawn from two randomised controlled trials (RCTs) testing two forms of FBT (conjoint/whole family and parent-focussed). Descriptive statistics and generalised estimating equations were used to examine differences in treatment outcomes between non-cognitive responders (NCRs) (those who regained weight but continued to experience psychological symptoms) and full responders (FRs) (those who achieved both weight and cognitive restoration by the end of treatment) (n = 80; 83.7% female, Agemean [SD] = 14.66 [1.73]).ResultsBy 12 months post-treatment, there were no differences in weight between NCRs and FRs. However, NCRs had a slower trajectory of weight gain than FRs and continued to have elevated levels of psychological symptoms throughout the follow-up period.ConclusionsA subset of adolescents appear to continue to experience clinically significant levels of eating pathology up to 12 months after FBT even when weight restoration is achieved.

Published
2023

29. Expressed emotion and long‐term outcome among adolescents with anorexia nervosa

Author

Rienecke, Renee D, Gorrell, Sasha, Blalock, Dan V, Smith, Kathryn, Lock, James, and Le Grange, Daniel

Subjects
Paediatrics, Biomedical and Clinical Sciences, Anorexia, Brain Disorders, Mental Health, Serious Mental Illness, Nutrition, Clinical Trials and Supportive Activities, Clinical Research, Eating Disorders, Behavioral and Social Science, Mind and Body, Depression, Pediatric, Mental health, Adolescent, Anorexia Nervosa, Expressed Emotion, Humans, Parents, Psychopathology, Treatment Outcome, adolescents, anorexia nervosa, expressed emotion, long-term follow-up, treatment outcome, Medical and Health Sciences, Psychology and Cognitive Sciences, Clinical Psychology, Nutrition and dietetics, Public health
Abstract

ObjectiveThe purpose of the current study is to examine expressed emotion (EE) and long-term treatment outcome among adolescents participating in a randomized controlled trial (RCT) for treatment of anorexia nervosa (AN). It was hypothesized that patients with high EE parents at baseline would show more severe symptoms at end-of-treatment, 12-month follow-up, and 4-year follow-up than patients from low EE families.MethodSecondary data analysis was conducted of original RCT data from a two-site eating disorder treatment trial conducted in the United States. Participants were 121 adolescents with AN who completed measures of EE, eating disorder psychopathology, depression, and self-esteem.ResultsGeneralized estimating equations showed that participants who were in the Low EE group achieved a more accelerated drop in depression scores in the context of treatment (first 12 months) than participants in the High EE group. No other significant Group × Time interactions were found.DiscussionFindings suggest that high parental EE at baseline does not indicate that adolescent patients with AN will fare poorly 4 years later.

Published
2021

31. A multitiered analysis platform for genome sequencing: Design and initial findings of the Australian Genomics Cardiovascular Disorders Flagship

Author

Ades, Lesley, Enriquez, Annabel, McLean, Alison, Smyth, Renee, Alankarage, Dimithu, Fatkin, Diane, McNamara, James, Soka, Magdalena, Morgan almog, Fear, Vanessa, Medi, Caroline, Stark, Zornitza, Al-Shinnag, Mohammad, Fine, Miriam, Metke, Alejandro, Sy, Raymond, Atherton, John J., Finlay, Keri, Milnes, Di, Tang, Dotti, Austin, Rachel, Garza, Denisse, Milward, Michael, Taylor, Jessica, Bagnall, Richard D., Giannoulatou, Eleni, Morrish, Ansley, Taylor, Shelby, Barnett, Chris, Gongolidis, Laura, Morwood, Jim, Tchan, Michel, Blue, Gillian M., Gray, Belinda, Mountain, Helen, Thompson, Tina, Bodek, Simon, Greer, Cassie, Mowat, David, Thorpe, Jordan, Boggs, Kirsten, Haan, Eric, Ng, Chai-Ann, Trainer, Alison, Bogwitz, Michael, Haas, Mathilda, Nowak, Natalie, Trivedi, Gunjan, Boughtwood, Tiffany, Hanna, Bernadette, Martinez, Noelia Nunez, Valente, Giulia, Bray, Alessandra, Harvey, Richard, Ohanian, Monique, van Spaendonck-Zwarts, Karin, Brion, Marie-Jo, Hayward, Janette, O’Sullivan, Sinead, Vandenberg, Jamie, Brown, Jaye, Herrera, Carmen, Overkov, Angela, Verma, Kunal, Richardson, Rob Bryson, Hill, Adam, Pachter, Nicholas, Vidgen, Miranda, Burnett, Leslie, Hollingsworth, Georgie, Patel, Chirag, Vohra, Jitendra, Burns, Charlotte, Hollway, Georgina, Perrin, Mark, Waddel-Smith, Kathryn, Cao, Michelle, Horton, Ari E., Perry, Matthew, Wallis, Mathew, Carr, Will, Howting, Denise, Pflaumer, Andreas, Weintraub, Robert G., Casauria, Sarah, Ingles, Jodie, Phillips, Peta, Wilson, Meredith, Chalinor, Heather, Isbister, Joanne, Phuong, Thuan, Winlaw, David, Chang, Yuchen, Jackson, Matilda, Pope-Couston, Rachel, Worgan, Lisa, Chapman, Gavin, James, Paul, Poplawski, Nicola K., Wornham, Linda, Charitou, Theosodia, Jane-Pantaleo, Sarah, Punni, Preeti, Wu, Kathy, Chong, Belinda, Johnson, Renee, Quinn, Michael C.J., Yeates, Laura, Collins, Felicity, Kelly, Andrew, Quinn, Michael, Zentner, Dominica, Correnti, Gemma, King-Smith, Sarah, Rajagopalan, Sulekha, Cox, Kathy, Kirk, Edwin, Raju, Hariharan, Cunningham, Fiona, Kummerfeld, Sarah, Rath, Emma M., Das, Debjani, Lassman, Timo, Regan, Matthew, Davis, Jason, Lipton, Jonathon, Rogers, Jonathan, Davis, Andrew, Lunke, Sebastian, Ryan, Mark, De Fazio, Paul, Macciocca, Ivan, Sandaradura, Sarah, de Silva, Michelle, MacIntyre, Paul, Schonrock, Nicole, Den Elzen, Nicola, Madelli, Evanthia O., Scuffham, Paul, Devery, Sophie, Mallawaarachchi, Amali, Semsarian, Chris, Dobbins, Julia, Mansour, Julia, Sherburn, Isabella, Dunwoodie, Sally L., Martin, Ellenore, Sherlock, Mary-Clare, Dwyer, Nathan, Mathew, Jacob, Singer, Emma, Elbracht-Leong, Stefanie, Mattiske, Tessa, Smerdon, Carla, Elliott, David, McGaughran, Julie, Smith, Janine, Brown, Jaye S., Haas, Matilda, and Pantaleo, Sarah-Jane

Published
2024
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38. Examining the roles of emotion dysregulation and impulsivity in the relationship between psychological trauma and substance abuse among women with bulimic-spectrum pathology

Author

Schaefer, Lauren M, Hazzard, Vivienne M, Smith, Kathryn E, Johnson, Cassandra A, Cao, Li, Crosby, Ross D, Peterson, Carol B, Crow, Scott J, Bardone-Cone, Anna M, Joiner, Thomas E, Le Grange, Daniel, Klein, Marjorie H, Mitchell, James E, and Wonderlich, Stephen A

Subjects
Psychology, Clinical and Health Psychology, Criminology, Human Society, Physical Injury - Accidents and Adverse Effects, Brain Disorders, Mental Health, Pediatric, Child Abuse and Neglect Research, Violence Research, Clinical Research, Mind and Body, Substance Misuse, Behavioral and Social Science, 2.1 Biological and endogenous factors, 2.3 Psychological, social and economic factors, Aetiology, Mental health, Good Health and Well Being, Bulimia, Child, Child Abuse, Emotions, Female, Humans, Impulsive Behavior, Psychological Trauma, Substance-Related Disorders, Medical and Health Sciences, Studies in Human Society, Psychology and Cognitive Sciences, Clinical Psychology, Health sciences, Human society
Abstract

Individuals with bulimia nervosa report elevated rates of childhood maltreatment, which appears to increase risk for co-occurring substance use problems and negatively impact clinical course. The current study sought to examine the mechanistic pathways by which specific forms of childhood maltreatment may give rise to substance use problems among individuals with bulimic-spectrum pathology. Women with bulimic-spectrum disorders (N = 204) completed measures of childhood trauma, emotion dysregulation, impulsivity, and substance use. Path analysis was used to examine emotion dysregulation and impulsivity as mediators of the relationship between distinct forms of childhood trauma (physical abuse, physical neglect, emotional abuse, emotional neglect, and sexual abuse) and the presence of problematic alcohol/drug use. In the full path model, significant pathways from childhood emotional abuse to emotion dysregulation, childhood emotional neglect to impulsivity, and emotion dysregulation to problematic substance use emerged. Further, emotion dysregulation significantly mediated the relationship between emotional abuse and substance use. Results indicate that emotion dysregulation may be an important mechanism linking a history of childhood emotional maltreatment to later eating and substance use problems, and therefore may be an important treatment target among individuals with co-occurring eating and substance use concerns.Childhood emotional abuse was related to greater emotion dysregulation.Childhood emotional neglect was related to greater impulsivity.Emotion dysregulation was related to greater problematic substance use.Emotional abuse may impact substance use through emotion dysregulation.Creating emotion dysregulation may improve substance and eating disorder symptoms.

Published
2021

44. Modeling Complex Word Reading: Examining Influences at the Level of the Word and Child on Mono- and Polymorphemic Word Reading

Author

Steacy, Laura M., Rigobon, Valeria M., Edwards, Ashley A., Abes, Daniel R., Marencin, Nancy C., Smith, Kathryn, Elliott, James D., Wade-Woolley, Lesly, and Compton, Donald L.

Abstract

Purpose: The probability of a child reading a word correctly is influenced by both child skills and properties of the word. The purpose of this study was to investigate child-level skills (set for variability and vocabulary), word-level properties (concreteness), word structure (mono- vs polymorphemic), and interactions between these properties and word structure within a comprehensive item-level model of complex word reading. This study is unique in that it purposely sampled both mono- and polymorphemic polysyllabic words. Method: A sample of African American (n = 69) and Hispanic (n = 6) students in grades 2-5 (n = 75) read a set of mono- and polymorphemic polysyllabic words (J = 54). Item-level responses were modeled using cross-classified generalized random-effects models allowing variance to be partitioned between child and word while controlling for other important child factors and word features. Results: Set for variability and the interaction between concreteness and word structure (i.e., mono- vs polymorphemic) were significant predictors. Higher probabilities of reading poly- over monomorphemic words were identified at lower levels of concreteness with the opposite at higher levels of concreteness. Conclusions: Results indicate important predictors at both the child- and word-level and support the importance of morphological structure for reading abstract polysyllabic words.

Published
2022
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46. Differences in Affective Dynamics Among Eating-Disorder Diagnostic Groups

Author

Williams-Kerver, Gail A, Wonderlich, Stephen A, Crosby, Ross D, Cao, Li, Smith, Kathryn E, Engel, Scott G, Crow, Scott J, Peterson, Carol B, Mitchell, James E, and Le Grange, Daniel

Subjects
Clinical and Health Psychology, Psychology, Anorexia, Mental Health, Brain Disorders, Clinical Research, Eating Disorders, Serious Mental Illness, Nutrition, 2.3 Psychological, social and economic factors, Aetiology, eating disorders, ecological momentary assessment, EMA, affective dynamics, negative affect, Applied and developmental psychology, Clinical and health psychology, Social and personality psychology
Abstract

Emotion regulation theories suggest that affect intensity is crucial in the development and maintenance of eating disorders. However, other aspects of emotional experience, such as lability, differentiation, and inertia, are not as well understood. This study is the first to use ecological momentary assessment (EMA) to examine differences in several daily negative affect (NA) indicators among adults diagnosed with anorexia nervosa (AN), bulimia nervosa (BN), or binge eating disorder (BED). Using EMA data from three large studies, a series of linear mixed models showed that participants in the AN and BN groups experienced significantly greater NA intensity and better emotion differentiation than participants in the BED group. Alternatively, the BN group demonstrated significantly greater NA lability than the AN group and greater NA inertia than the BED group. These results suggest that several daily affective experiences differ among eating disorders diagnostic groups and have implications towards distinct conceptualizations and treatments.

Published
2020

47. Somatic symptoms and binge eating in women's daily lives.

Author

Romano, Kelly A, Heron, Kristin E, Smith, Kathryn E, Crosby, Ross D, Engel, Scott G, Wonderlich, Stephen A, Pang, Raina D, and Mason, Tyler B

Subjects
Humans, Body Mass Index, Bulimia, Adult, Female, Young Adult, Surveys and Questionnaires, Medically Unexplained Symptoms, Binge eating, Eating disorders, Somatic symptoms, Women's health, Clinical Research, Behavioral and Social Science, Pain Research, Eating Disorders, Chronic Pain, Mental Health, Nutrition, Psychiatry, Medical and Health Sciences, Psychology and Cognitive Sciences
Abstract

ObjectiveThe present study aimed to determine whether the momentary severity of women's somatic symptoms was concurrently and prospectively associated with their engagement in binge eating in naturalistic settings.MethodThirty women (Mage = 34.13, SD = 13.92) who had engaged in binge eating at least once over the month prior to study entry completed a 14-day ecological momentary assessment (EMA) protocol. During each of the 14 days, participants received five semi-random surveys via text message that assessed momentary somatic symptom severity (i.e., headaches, stomachaches/pain, chest/heart pain, faintness/dizziness, shortness of breath, fatigue) and disordered eating behaviors. Generalized estimating equations were used to determine whether momentary somatic symptoms were concurrently and prospectively (i.e., by participants' next assessment) associated with the occurrence of binge eating behavior, while controlling for age and body mass index.ResultsAt the within-person level, more severe stomachaches/pain, faintness/dizziness, shortness of breath, and fatigue were concurrently associated with an increased likelihood of engaging in binge eating. Further, at the between-person level, more severe stomachaches/pain, chest/heart pain, shortness of breath, and fatigue in general were associated with binge eating across the EMA protocol. Momentary stomachache/pain severity also prospectively predicted women's engagement in binge eating behavior at the next assessment.ConclusionsThe present results provide initial evidence that multiple somatic symptoms may serve as momentary correlates or proximal antecedents of binge eating behavior in women's daily lives. Somatic symptoms may consequently prove useful to target in eating disorder treatments, perhaps via interoceptive exposure interventions.

Published
2020

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