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36 results on '"Sly, Laurel"'

3. Airway recruitment of leukocytes in mice is dependent on alpha4-integrins and vascular cell adhesion molecule-1

Author

Chin, Jia En, Hatfield, Cheryl A., Winterrrowd, Greg E., Brashler, John R., Vonderfecht, Steven L., Fidler, Stephen F., Griffin, Robert L., Kolbasa, Karen P., Krzesicki, Raymond F., Sly, Laurel M., Staite, Nigel D., and Richards, Ivan M.

Subjects
Cell adhesion molecules -- Physiological aspects, Eosinophils -- Physiological aspects, Lungs -- Inflammation, Mice as laboratory animals -- Physiological aspects, Biological sciences
Abstract

Murine models of ovalbumin (OA)-induced pulmonary inflammation were utilized to role of vascular cell adhesion molecule-1 (VCAM-1) and alpha4-integrins expression in the leukocyte trafficking. Analysis of the airways of mice with OA-induced inflammation indicated the presence of OA-induce elevation of VCAM-1 expression in the murine pulmonary vascular tissue. Furthermore, inhibition of VCAM-1 and alpha4-integrin expression reduced the accumulation of eosinophils and lymphocytes.

Published
1997

4. Role of intercellular adhesion molecule-1 in antigen-induced lung inflammation in Brown Norway rats

Author

Richards, Ivan M., Kolbasa, Karen P., Winterrowd, Greg E., Hatfield, Cheryl A., Vonderefecht, Steven L., Fidler, Stephen F., Griffin, Robert L., Brashler, John R., Krzesicki, Raymond F., Lane, Caryl L., Anderson, Donald C., Sly, Laurel M., Staite, Nigel D., and Chin, Jia En

Subjects
Cell adhesion molecules -- Physiological aspects, Antigens -- Physiological aspects, Lungs -- Inflammation, Rats as laboratory animals -- Observations, Biological sciences
Abstract

Intercellular adhesion molecule-1 is an important molecule in the development of ovalbumin antigen-induced lung inflammation in rats. Due to the induction of ovalbumin, influx of lymphocyte and eosinophil-rich inflammatory cells occurs in the respiratory tract. Anti-intercellular adhesion molecule-1 monoclonal antibody stops the antigen-induced recruitment of eosinophils and lymphocytes into the airway lumen.

Published
1996

5. Involvement of Intercellular Adhesion Molecule-1 in the Antigen-induced Infiltration of Eosinophils and Lymphocytes into the Airways in a Murine Model of Pulmonary Inflammation

Author

Chin, Jia En, Winterrowd, Greg E., Hatfield, Cheryl A., Brashler, John R., Griffin, Robert L., Vonderfecht, Steven L., Kolbasa, Karen P., Fidler, Stephen F., Shull, Kathy L., Krzesicki, Raymond F., Ready, Kathleen A., Dunn, Colin J., Sly, Laurel M., Staite, Nigel D., and Richards, Ivan M.

Published
1998
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14. Inhibition of Delayed-Type Contact Hypersensitivity in Mice Deficient in Both E-Selectin and P-Selectin

Author

Staite, Nigel D., Justen, James M., Sly, Laurel M., Beaudet, Arthur L, and Bullard, Daniel C.

Abstract

Leukocyte rolling and emigration in response to inflammatory stimuli appears to involve both E-selectin- and P-selectin-dependent adhesion, which suggests that these molecules have overlapping functions. To clarify their relative contributions in chronic inflammation, we examined delayed-type contact hypersensitivity (DTH) responses in P-selectin, E-selectin, and E-/P-selectin-deficient mice. Oxazolone-induced increases in ear thickness and ear weight were equivalent in wild-type mice and in P-selectin and E-selectin mutants, but were significantly reduced in E-/P-selectin mutants. The number and area of microabscesses on the ears of E-/P-deficient mice were decreased by 72% and 93%, and the number of leukocytes invading the subdermal ear tissue was reduced. T cells from E-/P-deficient mice transferred oxazolone reactivity into naive wild-type mice. However, when donor T cells from wild-type mice were transferred into E-/P-selectin-deficient mice, the DTH response was significantly impaired. These results show that leukocyte recruitment into a subacute inflammatory reaction can occur when either P-selectin or E-selectin is present, but is significantly reduced when both selectins are absent. Both P- and E-selectin are likely to play important roles in the development and maintenance of inflammatory diseases.

Published
1996
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16. Additional file 5 of Pulmonary and systemic responses to aerosolized lysate of Staphylococcus aureus and Escherichia coli in calves

Author

Bassel, Laura L., Carmon Co, Macdonald, Alaina, Sly, Laurel, McCandless, Erin E., Hewson, Joanne, Raksha Tiwari, Shayan Sharif, Siracusa, Laura, Clark, Mary Ellen, and Caswell, Jeff L.

Subjects
respiratory system, 3. Good health
Abstract

Additional file 5. Bronchoalveolar lavage fluid protein concentrations in calves prior to and 24 and 96 h post-aerosolization of bacterial lysate or saline.

17. Additional file 7 of Pulmonary and systemic responses to aerosolized lysate of Staphylococcus aureus and Escherichia coli in calves

Author

Bassel, Laura L., Carmon Co, Macdonald, Alaina, Sly, Laurel, McCandless, Erin E., Hewson, Joanne, Raksha Tiwari, Shayan Sharif, Siracusa, Laura, Clark, Mary Ellen, and Caswell, Jeff L.

Subjects
respiratory system, 3. Good health
Abstract

Additional file 7. PANTHER classification of 19 upregulated proteins and 26 downregulated proteins in bronchoalveolar lavage fluid following aerosolization of bacterial lysate in 4 calves.

18. Additional file 8 of Pulmonary and systemic responses to aerosolized lysate of Staphylococcus aureus and Escherichia coli in calves

Author

Bassel, Laura L., Carmon Co, Macdonald, Alaina, Sly, Laurel, McCandless, Erin E., Hewson, Joanne, Raksha Tiwari, Shayan Sharif, Siracusa, Laura, Clark, Mary Ellen, and Caswell, Jeff L.

Subjects
respiratory system, respiratory tract diseases, 3. Good health
Abstract

Additional file 8. Reactome pathway analysis for differently expressed proteins in bronchoalveolar lavage fluid in 4 calves.

19. Additional file 9 of Pulmonary and systemic responses to aerosolized lysate of Staphylococcus aureus and Escherichia coli in calves

Author

Bassel, Laura L., Carmon Co, Macdonald, Alaina, Sly, Laurel, McCandless, Erin E., Hewson, Joanne, Raksha Tiwari, Shayan Sharif, Siracusa, Laura, Clark, Mary Ellen, and Caswell, Jeff L.

Subjects
respiratory system, 3. Good health
Abstract

Additional file 9. Gross lung lesions at 24 h after aerosol administration of Staphylococcus aureus and Escherichia coli lysate.

20. Additional file 3 of Pulmonary and systemic responses to aerosolized lysate of Staphylococcus aureus and Escherichia coli in calves

Author

Bassel, Laura L., Carmon Co, Macdonald, Alaina, Sly, Laurel, McCandless, Erin E., Hewson, Joanne, Raksha Tiwari, Shayan Sharif, Siracusa, Laura, Clark, Mary Ellen, and Caswell, Jeff L.

Subjects
respiratory system, respiratory tract diseases, 3. Good health
Abstract

Additional file 3. Bronchoalveolar lavage fluid cytology before and 24 h after aerosolization of bacterial lysate.

21. Additional file 3 of Pulmonary and systemic responses to aerosolized lysate of Staphylococcus aureus and Escherichia coli in calves

Author

Bassel, Laura L., Carmon Co, Macdonald, Alaina, Sly, Laurel, McCandless, Erin E., Hewson, Joanne, Raksha Tiwari, Shayan Sharif, Siracusa, Laura, Clark, Mary Ellen, and Caswell, Jeff L.

Subjects
respiratory system, respiratory tract diseases, 3. Good health
Abstract

Additional file 3. Bronchoalveolar lavage fluid cytology before and 24 h after aerosolization of bacterial lysate.

22. Additional file 10 of Pulmonary and systemic responses to aerosolized lysate of Staphylococcus aureus and Escherichia coli in calves

Author

Bassel, Laura L., Carmon Co, Macdonald, Alaina, Sly, Laurel, McCandless, Erin E., Hewson, Joanne, Raksha Tiwari, Shayan Sharif, Siracusa, Laura, Clark, Mary Ellen, and Caswell, Jeff L.

Subjects
3. Good health
Abstract

Additional file 10. Histologic lesions in respiratory tissues from 4 calves treated with aerosolized Staphylococcus aureus and Escherichia coli lysate.

24. Additional file 2 of Pulmonary and systemic responses to aerosolized lysate of Staphylococcus aureus and Escherichia coli in calves

Author

Bassel, Laura L., Carmon Co, Macdonald, Alaina, Sly, Laurel, McCandless, Erin E., Hewson, Joanne, Raksha Tiwari, Shayan Sharif, Siracusa, Laura, Clark, Mary Ellen, and Caswell, Jeff L.

Subjects
fluids and secretions, animal structures, animal diseases, reproductive and urinary physiology, 3. Good health
Abstract

Additional file 2. Bronchoalveolar lavage fluid cells pre- and post- administration of differing doses of bacterial lysate or saline in Holstein bull calves.

26. Additional file 2 of Pulmonary and systemic responses to aerosolized lysate of Staphylococcus aureus and Escherichia coli in calves

Author

Bassel, Laura L., Carmon Co, Macdonald, Alaina, Sly, Laurel, McCandless, Erin E., Hewson, Joanne, Raksha Tiwari, Shayan Sharif, Siracusa, Laura, Clark, Mary Ellen, and Caswell, Jeff L.

Subjects
fluids and secretions, animal structures, animal diseases, reproductive and urinary physiology, 3. Good health
Abstract

Additional file 2. Bronchoalveolar lavage fluid cells pre- and post- administration of differing doses of bacterial lysate or saline in Holstein bull calves.

27. Additional file 6 of Pulmonary and systemic responses to aerosolized lysate of Staphylococcus aureus and Escherichia coli in calves

Author

Bassel, Laura L., Carmon Co, Macdonald, Alaina, Sly, Laurel, McCandless, Erin E., Hewson, Joanne, Raksha Tiwari, Shayan Sharif, Siracusa, Laura, Clark, Mary Ellen, and Caswell, Jeff L.

Subjects
respiratory system, 3. Good health
Abstract

Additional file 6. Mass spectrometry data for proteins in bronchoalveolar lavage fluid in 4 calves (A4, A3, A5, A6) before and 24 h after aerosolization with heat-killed lysate of Escherichia coli and Staphylococcus aureus.

28. Additional file 10 of Pulmonary and systemic responses to aerosolized lysate of Staphylococcus aureus and Escherichia coli in calves

Author

Bassel, Laura L., Carmon Co, Macdonald, Alaina, Sly, Laurel, McCandless, Erin E., Hewson, Joanne, Raksha Tiwari, Shayan Sharif, Siracusa, Laura, Clark, Mary Ellen, and Caswell, Jeff L.

Subjects
3. Good health
Abstract

Additional file 10. Histologic lesions in respiratory tissues from 4 calves treated with aerosolized Staphylococcus aureus and Escherichia coli lysate.

30. Additional file 8 of Pulmonary and systemic responses to aerosolized lysate of Staphylococcus aureus and Escherichia coli in calves

Author

Bassel, Laura L., Carmon Co, Macdonald, Alaina, Sly, Laurel, McCandless, Erin E., Hewson, Joanne, Raksha Tiwari, Shayan Sharif, Siracusa, Laura, Clark, Mary Ellen, and Caswell, Jeff L.

Subjects
respiratory system, respiratory tract diseases, 3. Good health
Abstract

Additional file 8. Reactome pathway analysis for differently expressed proteins in bronchoalveolar lavage fluid in 4 calves.

31. Additional file 7 of Pulmonary and systemic responses to aerosolized lysate of Staphylococcus aureus and Escherichia coli in calves

Author

Bassel, Laura L., Carmon Co, Macdonald, Alaina, Sly, Laurel, McCandless, Erin E., Hewson, Joanne, Raksha Tiwari, Shayan Sharif, Siracusa, Laura, Clark, Mary Ellen, and Caswell, Jeff L.

Subjects
respiratory system, 3. Good health
Abstract

Additional file 7. PANTHER classification of 19 upregulated proteins and 26 downregulated proteins in bronchoalveolar lavage fluid following aerosolization of bacterial lysate in 4 calves.

32. Additional file 1 of Pulmonary and systemic responses to aerosolized lysate of Staphylococcus aureus and Escherichia coli in calves

Author

Bassel, Laura L., Carmon Co, Macdonald, Alaina, Sly, Laurel, McCandless, Erin E., Hewson, Joanne, Raksha Tiwari, Shayan Sharif, Siracusa, Laura, Clark, Mary Ellen, and Caswell, Jeff L.

Subjects
animal structures, animal diseases, food and beverages, respiratory system, complex mixtures, 3. Good health
Abstract

Additional file 1. Clinical parameters over time following aerosolization in 6 Holstein calves following aerosolization of bacterial lysate.

35. Additional file 6 of Pulmonary and systemic responses to aerosolized lysate of Staphylococcus aureus and Escherichia coli in calves

Author

Bassel, Laura L., Carmon Co, Macdonald, Alaina, Sly, Laurel, McCandless, Erin E., Hewson, Joanne, Raksha Tiwari, Shayan Sharif, Siracusa, Laura, Clark, Mary Ellen, and Caswell, Jeff L.

Subjects
respiratory system, 3. Good health
Abstract

Additional file 6. Mass spectrometry data for proteins in bronchoalveolar lavage fluid in 4 calves (A4, A3, A5, A6) before and 24 h after aerosolization with heat-killed lysate of Escherichia coli and Staphylococcus aureus.

36. Additional file 5 of Pulmonary and systemic responses to aerosolized lysate of Staphylococcus aureus and Escherichia coli in calves

Author

Bassel, Laura L., Carmon Co, Macdonald, Alaina, Sly, Laurel, McCandless, Erin E., Hewson, Joanne, Raksha Tiwari, Shayan Sharif, Siracusa, Laura, Clark, Mary Ellen, and Caswell, Jeff L.

Subjects
respiratory system, 3. Good health
Abstract

Additional file 5. Bronchoalveolar lavage fluid protein concentrations in calves prior to and 24 and 96 h post-aerosolization of bacterial lysate or saline.

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