203 results on '"Slupsky, Joseph R."'
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2. Roles of PI3Kγ and PI3Kδ in mantle cell lymphoma proliferation and migration contributing to efficacy of the PI3Kγ/δ inhibitor duvelisib
3. Soluble CTLA-4 attenuates T cell activation and modulates anti-tumor immunity
4. Multiplexed profiling of RNA and protein expression signatures in individual cells using flow or mass cytometry
5. Soluble CTLA-4 raises the threshold for T-cell activation and modulates anti-tumour immunity
6. A novel transgenic mouse strain expressing PKCβII demonstrates expansion of B1 and marginal zone B cell populations
7. Supplementary legends from New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome
8. Data from New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome
9. Supplementary Table 1 from New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome
10. Supplementary Table 3 from New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome
11. Supplementary Table 4 from New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome
12. Supplementary Table 1 from c-Abl Expression in Chronic Lymphocytic Leukemia Cells: Clinical and Therapeutic Implications
13. Supplementary Plot 1 from c-Abl Expression in Chronic Lymphocytic Leukemia Cells: Clinical and Therapeutic Implications
14. Mechanisms of monoclonal antibody-induced platelet activation
15. PKCβ Facilitates Leukemogenesis in Chronic Lymphocytic Leukaemia by Promoting Constitutive BCR-Mediated Signalling
16. Development of a bispecific Antibody–Drug Conjugate targeting CD7 and CD33 to treat Acute Myeloid Leukaemia
17. Cancerous inhibitor of PP2A (CIP2A) at diagnosis of chronic myeloid leukemia is a critical determinant of disease progression
18. c-Abl regulates Mcl-1 gene expression in chronic lymphocytic leukemia cells
19. UHRF1 regulation of the Keap1–Nrf2 pathway in pancreatic cancer contributes to oncogenesis
20. Vascular endothelial growth factor stimulates protein kinase CβII expression in chronic lymphocytic leukemia cells
21. Kinobead Profiling Reveals Reprogramming of BCR Signaling in Response to Therapy within Primary CLL Cells
22. Poor prognosis is ZAP70’ed into focus in CLL
23. B-cell receptor signaling in chronic lymphocytic leukemia cells is regulated by overexpressed active protein kinase CβII
24. Regulation of hairy-cell survival through constitutive activation of mitogen-activated protein kinase pathways
25. Mitogenic signaling of Ras is regulated by differential interaction with Raf isozymes
26. Loss ofBAP1expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development
27. CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells
28. Differential expression and regulation of protease-activated receptors in human peripheral monocytes and monocyte-derived antigen-presenting cells
29. The role of autocrine FGF-2 in the distinctive bone marrow fibrosis of hairy-cell leukemia (HCL)
30. Ibrutinib is safer than we think
31. Response of hairy cells to IFN-α involves induction of apoptosis through autocrine TNF-α and protection by adhesion
32. Analysis of CD9, CD32 and p67 signalling: use of degranulated platelets indicates direct involvement of CD9 and p67 in integrin activation
33. Loss of BAP1 expression is associated with an immunosuppressive microenvironment in uveal melanoma, with implications for immunotherapy development.
34. Gene Editing of BTK in Acute Myeloid Leukaemia Using CRISPR-Cas9
35. New Perspectives, Opportunities, and Challenges in Exploring the Human Protein Kinome
36. Lck is a relevant target in chronic lymphocytic leukaemia cells whose expression variance is unrelated to disease outcome
37. Transcriptional mechanism of vascular endothelial growth factor-induced expression of protein kinase CβII in chronic lymphocytic leukaemia cells
38. Does B Cell Receptor Signaling in Chronic Lymphocytic Leukaemia Cells Differ from That in Other B Cell Types?
39. Targeting B-Cell Receptor Signaling in Leukemia and Lymphoma: How and Why?
40. UHRF1 regulation of the Keap1–Nrf2 pathway in pancreatic cancer contributes to oncogenesis
41. CLL Exosomes Modulate the Transcriptome and Behaviour of Recipient Stromal Cells and Are Selectively Enriched in miR-202-3p
42. Immunohistochemical analysis indicates that the anatomical location of B-cell non-Hodgkin’s lymphoma is determined by differentially expressed chemokine receptors, sphingosine-1-phosphate receptors and integrins
43. Expression of Functional Sphingosine-1 Phosphate Receptor-1 Is Reduced by B Cell Receptor Signaling and Increased by Inhibition of PI3 Kinase δ but Not SYK or BTK in Chronic Lymphocytic Leukemia Cells
44. Enhancing BCR signals at the cell membrane
45. CALSEQUESTRIN121Supported by grants from the Medical Research Council of Canada (D.H.M.), the Heart and Stroke Foundation of Ontario (D.H.M.), the Muscular Dystrophy Association of Canada (D.H.M. and R.A.F.R.) and the Alberta Heritage Foundation for Medical Research (R.A.F.R and M.O.).2Present address: Membrane Biology Group, Department of Medicine, Room 7307, Medical Sciences Building, University of Toronto, Toronto, Ontario, Canada M5S 1A8
46. Variable induction of PRDM1 and differentiation in chronic lymphocytic leukemia is associated with anergy
47. The B Lymphocyte Differentiation Factor (BAFF) Is Expressed in the Airways of Children with CF and in Lungs of Mice Infected with Pseudomonas aeruginosa
48. LCK Is an Important Mediator of B-Cell Receptor Signaling in Chronic Lymphocytic Leukemia Cells
49. 2.5 Lck is an Important Mediator of BCR-induced Signaling in CLL Cells
50. C-Abl Regulates Mcl-1 Gene Expression In Chronic Lymphocytic Leukaemia Cells
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