239 results on '"Slomp, J."'
Search Results
2. A positive effect of immune suppression on corrected count increment after platelet transfusion at 1 but not at 24 h
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Dijkstra-Tiekstra, M.J., Rondeel, J.M.M., Slomp, J., Smid, W.M., and de Wildt-Eggen, J.
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- 2013
- Full Text
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3. Blended Network Action Learning – A Digital Lean Approach to Solving Complex Organizational Problems Across Space and Time
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Powell, D.J, Vries, M. de, Roij, M.J.P.A.M. van, and Slomp, J.
- Abstract
Network Action Learning has emerged as an innovative development of Action Learning and has been described as a lean approach to collaborative strategic improvement with problem-solving at its core, be it either within- or across organizational boundaries. Virtual Action Learning is also presented as an emergent variety of Action Learning, bringing together geographically dispersed individuals within and across organizations in an online, virtual environment. Given the onset of new, innovative digital technologies – particularly in response of the Covid-19 pandemic – Blended Learning has also emerged as an educational platform that represents some combination of face-to-face and online learning using mobile technologies and cloud-based resources. Though Virtual Action Learning has been discussed as neither better than nor second best to face-to-face Action Learning, in this paper, we suggest that a blended approach may be the most effective method. Thus, the purpose of this paper is to construct a Blended approach to Network Action Learning, where intra- and inter-firm Network Action Learning can take place using a hybrid, physical-virtual approach to promoting collaborative strategic improvement and gemba-based problem-solving.
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- 2021
4. Aanvraag RAAK-MKB project 'Flexibele Werkinstructies'
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Hoppenbrouwers, S.J.B.A., Corsius, M., and Slomp, J.
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- 2022
5. Design of Manufacturing Cells: PFA Applications in Dutch Industry
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Slomp, J., Suresh, Nallan C., editor, and Kay, John M., editor
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- 1998
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6. The design and operation of flexible manufacturing shops
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Slomp, J., Artiba, A., editor, and Elmaghraby, S. E., editor
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- 1997
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7. Harmonizing light transmission aggregometry in the Netherlands by implementation of the SSC-ISTH guideline
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Munnix, I.C.A., Van Oerle, R., Verhezen, P., Kuijper, P., Hackeng, C.M., Hopman-Kerkhoff, H.I.J., Hudig, F., van de Kerkhof, D., Leyte, A., de Maat, M.P.M., Oude Elferink, R.F.M., Ruinemans-Koerts, J., Schoorl, M., Slomp, J., Soons, H., Stroobants, A., van Wijk, E., Henskens, Y.M.C., Munnix, I.C.A., Van Oerle, R., Verhezen, P., Kuijper, P., Hackeng, C.M., Hopman-Kerkhoff, H.I.J., Hudig, F., van de Kerkhof, D., Leyte, A., de Maat, M.P.M., Oude Elferink, R.F.M., Ruinemans-Koerts, J., Schoorl, M., Slomp, J., Soons, H., Stroobants, A., van Wijk, E., and Henskens, Y.M.C.
- Abstract
Light transmission aggregometry (LTA) is considered the gold standard method for evaluation of platelet function. However, there are a lot of variation in protocols (pre-analytical procedures and agonist concentrations) and results. The aim of our study was to establish a national LTA protocol, to investigate the effect of standardization and to define national reference values for LTA. The SSC guideline was used as base for a national procedure. Almost all recommendations of the SSC were followed e.g. no adjustment of PRP, citrate concentration of 109 mM, 21 needle gauge, fasting, resting time for whole blood and PRP, centrifugation time, speed and agonists concentrations. LTA of healthy volunteers was measured in a total of 16 hospitals with 5 hospitals before and after standardization. Results of more than 120 healthy volunteers (maximum aggregation %) were collected, with participating laboratories using 4 different analyzers with different reagents. Use of low agonist concentrations showed high variation before and after standardization, with the exception of collagen. For most high agonist concentrations (ADP, collagen, ristocetin, epinephrine and arachidonic acid) variability in healthy subjects decreased after standardization. We can conclude that a standardized Dutch protocol for LTA, based on the SSC guideline, does not result in smaller variability in healthy volunteers for all agonist concentrations.
- Published
- 2021
8. Harmonizing light transmission aggregometry in the Netherlands by implementation of the SSC-ISTH guideline
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Munnix, I. C.A., Van Oerle, R., Verhezen, P., Kuijper, P., Hackeng, C. M., Hopman-Kerkhoff, H. I.J., Hudig, F., Van De Kerkhof, D., Leyte, A., De Maat, M. P.M., Oude Elferink, R. F.M., Ruinemans-Koerts, J., Schoorl, M., Slomp, J., Soons, H., Stroobants, A., Van Wijk, E., Henskens, Y. M.C., Munnix, I. C.A., Van Oerle, R., Verhezen, P., Kuijper, P., Hackeng, C. M., Hopman-Kerkhoff, H. I.J., Hudig, F., Van De Kerkhof, D., Leyte, A., De Maat, M. P.M., Oude Elferink, R. F.M., Ruinemans-Koerts, J., Schoorl, M., Slomp, J., Soons, H., Stroobants, A., Van Wijk, E., and Henskens, Y. M.C.
- Abstract
Light transmission aggregometry (LTA) is considered the gold standard method for evaluation of platelet function. However, there are a lot of variation in protocols (pre-analytical procedures and agonist concentrations) and results. The aim of our study was to establish a national LTA protocol, to investigate the effect of standardization and to define national reference values for LTA. The SSC guideline was used as base for a national procedure. Almost all recommendations of the SSC were followed e.g. no adjustment of PRP, citrate concentration of 109 mM, 21 needle gauge, fasting, resting time for whole blood and PRP, centrifugation time, speed and agonists concentrations. LTA of healthy volunteers was measured in a total of 16 hospitals with 5 hospitals before and after standardization. Results of more than 120 healthy volunteers (maximum aggregation %) were collected, with participating laboratories using 4 different analyzers with different reagents. Use of low agonist concentrations showed high variation before and after standardization, with the exception of collagen. For most high agonist concentrations (ADP, collagen, ristocetin, epinephrine and arachidonic acid) variability in healthy subjects decreased after standardization. We can conclude that a standardized Dutch protocol for LTA, based on the SSC guideline, does not result in smaller variability in healthy volunteers for all agonist concentrations.
- Published
- 2021
9. Implementation of a new platelet pooling system for platelet concentrates led to a higher corrected count increment after transfusion: a comparative observational study of platelet concentrates before and after implementation
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Dijkstra-Tiekstra, M. J., van de Watering, L. M. G., Rondeel, J. M. M., Slomp, J., and de Wildt-Eggen, J.
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- 2014
- Full Text
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10. Workshop on the Move, How can car maintenance and repair be future-proofed in a disruptive time?
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Steen, A. van der, Veders, C.W.G., Herkes, M.C., Keiren, J., Tillema, F., Slomp, J., Stralen, W.A. van, and Koeleman, W.P.T.
- Abstract
In September 2017, the Lectorates LEAN & Worldclass Performance and Automotive Research of the HAN University of Applied Science, together with a consortium of (SME) industry partners, started the research project ‘Workshop on the Move’. The project is the search for the answer to the question as to the best way to organize repair and maintenance of passenger cars effectively and efficiently in the future. This project was financed by Regional Body SiA through the RAAK SME scheme and with co-financing of the consortium partners. The study was divided into five work packages. In each work package part of the workload was executed. Each work package was led by one of the consortium partners. Other consortium partners cooperated. The project management was in the hands of the HAN. On the basis of work sessions, desk research, focus groups, practical tests, interviews, case studies and student projects this research has: - mapped out the existing industry situation, - predicted changes for the industry until 2030, - determined six types of business using Formative Scenario Analysis (FSA) as a guide, - built a tool to give automotive entrepreneurs an indication of the best strategic business choice for the future, - validated interim results by consortium partners. Finally, the results of the project were translated into a visual representation, various presentations, a research report and a reference book for the automotive industry. The various publications can be found on the website www.werkplaatsopweg.nl.
- Published
- 2020
11. A new gene associated with a b-thalassemia phenotype: The observation of variants in SUPT5H
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Achour, A. Koopmann, T. Castel, R. Santen, G.W.E. den Hollander, N. Knijnenburg, J. Ruivenkamp, C.A.L. Arkesteijn, S.G.J. Huurne, J.T. Bisoen, S. Verschuren, M. Vijfhuizen, L. Schaap, R. Grimbergen, A. Slomp, J. Traeger-Synodinos, J. Vrettou, C. Pissard, S. Galacteros, F. Baas, F. Harteveld, C.L.
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- 2020
12. Prototyping a Routine Building-Intervention to Develop Towards a Lean Organization
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Knol, W.H., Lauche, K., Schouteten, R.L.J., and Slomp, J.
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- 2020
13. The Development of Continuous Improvement in SMEs and the Supportive Role of the A3 Tool
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Slomp, J., Oversluizen, G., Knol, W.H., and Rossi et al., Monica
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- 2020
14. Werkplaats op Weg, Hoe kan in een disruptieve tijd onderhoud en reparatie van auto’s toekomstbestendig worden georganiseerd?
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Steen, A. van der, Veders, C.W.G., Herkes, M.C., Keiren, J., Tillema, F., Slomp, J., Stralen, W.A. van, and Koeleman, W.P.T.
- Abstract
In september 2017 zijn de lectoraten LEAN & Worldclass Performance en Automotive Research van de HAN University of Applied Science, met een consortium van (mkb) branchepartners, gestart met het onderzoeksproject ‘Werkplaats op Weg’. Het project is de zoektocht naar het antwoord op de vraag naar de beste manier om reparatie en onderhoud van personenauto’s in de toekomst effectief en efficiënt te organiseren. Dit project werd gefinancierd door Regio-orgaan SiA door middel van de RAAK-mkb regeling en met cofinanciering van de consortiumpartners. Het onderzoek was opgedeeld in vijf werkpakketten. Elk werkpakket stond onder leiding van één van de consortiumpartners. Overige consortiumpartners verleenden hun medewerking. De projectleiding was in handen van de HAN. Aan de hand van o.a. werksessies, deskresearch, focusgroepen, praktijkproeven, interviews, casestudies en studentprojecten zijn: - de bestaande branchesituatie in kaart gebracht, - drivers voor veranderingen voor de branche tot 2030 vastgesteld, - met gebruik van Formatieve Scenario Analyse (FSA) als leidraad een zestal bedrijfstypes bepaald, - een tool gebouwd waarmee ondernemers in de autobranche een indicatie krijgen van de beste strategische bedrijfskeuze voor de toekomst, - tussentijdse resutaten gevalideerd bij consortiumpartners. Tenslotte zijn de resultaten van het project vertaald naar een visuele weergave, diverse presentaties, een onderzoeksrapport en een naslagwerk voor de autobranche. De diverse publicaties zijn te vinden op de website www.werkplaatsopweg.nl.
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- 2020
15. Applicability and reproducibility of acute myeloid leukaemia stem cell assessment in a multi-centre setting
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Hanekamp, D. (Diana), Snel, A.N. (Alexander), Kelder, A. (Angèle), Scholten, W.J. (Willemijn), Khan, N. (Naeem), Metzner, M. (Marlen), Irno-Consalvo, M. (Maria), Sugita, M. (Mayumi), Jong, A.X. (Anja) de, Oude Alink, S. (Sjoerd), Eidhof, H. (Harrie), Wilhelm, M. (Miriam), Feuring-Buske, M. (Michaela), Slomp, J. (Jennichjen), Velden, V.H.J. (Vincent) van der, Sonneveld, E. (Edwin), Guzman, M. (Monica), Roboz, G.J. (Gail J.), Buccisano, F. (Francesco), Vyas, P. (Paresh), Freeman, S. (Sylvie), Bachas, C. (Costa), Ossenkoppele, G.J. (Gert), Schuurhuis, G.J. (Gerrit Jan), Cloos, J. (Jacqueline), Hanekamp, D. (Diana), Snel, A.N. (Alexander), Kelder, A. (Angèle), Scholten, W.J. (Willemijn), Khan, N. (Naeem), Metzner, M. (Marlen), Irno-Consalvo, M. (Maria), Sugita, M. (Mayumi), Jong, A.X. (Anja) de, Oude Alink, S. (Sjoerd), Eidhof, H. (Harrie), Wilhelm, M. (Miriam), Feuring-Buske, M. (Michaela), Slomp, J. (Jennichjen), Velden, V.H.J. (Vincent) van der, Sonneveld, E. (Edwin), Guzman, M. (Monica), Roboz, G.J. (Gail J.), Buccisano, F. (Francesco), Vyas, P. (Paresh), Freeman, S. (Sylvie), Bachas, C. (Costa), Ossenkoppele, G.J. (Gert), Schuurhuis, G.J. (Gerrit Jan), and Cloos, J. (Jacqueline)
- Abstract
Leukaemic stem cells (LSC) have been experimentally defined as the leukaemia-propagating population and are thought to be the cellular reservoir of relapse in acute myeloid leukaemia (AML). Therefore, LSC measurements are warranted to facilitate accurate risk stratification. Previously, we published the composition of a one-tube flow cytometric assay, characterised by the presence of 13 important membrane markers for LSC detection.
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- 2020
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16. Applicability and reproducibility of acute myeloid leukaemia stem cell assessment in a multi-centre setting
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Hanekamp, D, Snel, A, Kelder, A, Scholten, WJ, Khan, NM, Metzner, M, Irno-Consalvo, M, Sugita, M, Jong, A, Oude Alink, Sjoerd, Eidhof, H, Wilhelm, MJ, Feuring-Buske, M, Slomp, J, van der Velden, Vincent, Sonneveld, EDJA, Guzman, MG, Roboz, GJ, Buccisano, F, Vyas, P, Freeman, SH, Bachas, C, Ossenkoppele, GL, Schuurhuis, GJ, Cloos, J, Hanekamp, D, Snel, A, Kelder, A, Scholten, WJ, Khan, NM, Metzner, M, Irno-Consalvo, M, Sugita, M, Jong, A, Oude Alink, Sjoerd, Eidhof, H, Wilhelm, MJ, Feuring-Buske, M, Slomp, J, van der Velden, Vincent, Sonneveld, EDJA, Guzman, MG, Roboz, GJ, Buccisano, F, Vyas, P, Freeman, SH, Bachas, C, Ossenkoppele, GL, Schuurhuis, GJ, and Cloos, J
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- 2020
17. Harmonizing light transmission aggregometry in the Netherlands by implementation of the SSC-ISTH guideline
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Munnix, I.C.A., primary, Van Oerle, R., additional, Verhezen, P., additional, Kuijper, P., additional, Hackeng, C.M., additional, Hopman-Kerkhoff, H.I.J., additional, Hudig, F., additional, Van De Kerkhof, D., additional, Leyte, A., additional, De Maat, M.P.M., additional, Oude Elferink, R.F.M., additional, Ruinemans-Koerts, J., additional, Schoorl, M., additional, Slomp, J., additional, Soons, H., additional, Stroobants, A., additional, Van Wijk, E., additional, and Henskens, Y.M.C., additional
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- 2020
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18. Association of Timing of Plasma Transfusion With Adverse Maternal Outcomes in Women With Persistent Postpartum Hemorrhage
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Henriquez, D.D.C.A., Caram-Deelder, C., Cessie, S. le, Zwart, J.J., Roosmalen, J.J.M. van, Eikenboom, J.C.J., So-Osman, C., Watering, L.G. van de, Zwaginga, J.J., Koopman-van Gemert, A.W.M.M., Bloemenkamp, K.W.M., Bom, J.G. van der, Bank, C.M.C., Snuif-de Lange, Y.S., Gammeren, A.J. van, Papatsonis, D.N.M., Klinkspoor, H., Kok, M., Boer, B.A. de, Langenveld, J., Leers, M.P.G., Diris, J.H.C., Kok, R.D., Engbers, P., Hanssen, M.J.C.P., Wijngaarden, W.J. van, Schippers, D.H., Stappen, J.J. van der, Hasaart, T.H.M., Kerkhof, D.H. van de, Kok, J.B. de, Unnik, G.A. van, Kortlandt, W., Schuitemaker, N.E., Delemarre, F.M.C., Duijnhoven, H.L.P. van, Duvekot, H.J., Hogenboom, S., Kleiverda, G., Etten-van Hulst, M.J.W. van, Mirani-Oostdijk, K.P., Kampen, C. van, Weinans, M.J.N., Adriaanse, H.J., Huisjes, A.J.M., Frasa, M.A.M., Keuren, J.F.W., Meir, C.A. van, Feitsma, H., Hudig, F., Sikkema, J.M., Baas, M.I., Fouraux, M.A., Hmetz, G.C., Bijvank, B.H.N., Rondeel, H.J.M., Roelofsen, J.M.T., Doesburg-van Kleffens, M., Wit, S.C. de, Versendaal, H., Weerkamp, F., Henskens, Y.M.C., Scheepers, L.H.C.J., Ham, D.P. van der, Smit, J.W., Graaf, F. van der, Porath, M.M., Salm, P.C.M. van der, Wijnen, M. van, Pontesilli, M., Dunne, F.M. van, Ponjee, G.A.E., Post, M.S., Veen, B.S. van der, Brons, J.T.J., Slomp, J., Mare, A. de, Leyte, A., Akker, E.S.A. van den, Wet, H. de, Borden, D.M.R. van der, Bremer, H.A., Tax, G.H.M., Vries, M.J. de, Boer, K. de, Waard, H. de, Keijzer, R.H. de, Burggraaff, J.M., Pouwels, J.G.J., Gemund, N. van, Prinzen, L., Hendriks, H.A., Hermsen, B.B.J., Koehorst, S.G.A., Verhagen, T.E.M., Beek, E. van, Hackeng, C.M., Kabel, P.J., Steures, P., Dooren, I.A. van, Michielse, E.C.H.J., Chon, H., Treskes, M., Visser, H., Oostenveld, E., Peters, D.H.M., Franssen, M.T.M., Meekers, J.H., Woiski, M.D., Pampus, L.C.M. van, Oudijk, M.A., Vooght, K.M.K. de, Cikot, R.L.M., Mostert, L.J., Ceelie, H., Huijssoon, A.M.G., Groot, C.J.M. de, Visser, O., Jonker, N., Koops, A., Hooker, A., Osmanovic, N., Ulenkate, H.J.L.M., Visschers, B., Martens, G.D.M., TeMpOH-Res Grp, Athena Institute, APH - Global Health, APH - Quality of Care, Reproductive Origins of Adult Health and Disease (ROAHD), Faculteit FHML Centraal, RS: CARIM - R1.04 - Clinical thrombosis and haemostasis, MUMC+: DA CDL Algemeen (9), Med Microbiol, Infect Dis & Infect Prev, Obstetrie & Gynaecologie, MUMC+: MA Medische Staf Obstetrie Gynaecologie (9), RS: GROW - R4 - Reproductive and Perinatal Medicine, RS: Carim - B04 Clinical thrombosis and Haemostasis, and Obstetrics & Gynecology
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Adult ,medicine.medical_specialty ,medicine.medical_treatment ,TRACHEAL INTUBATION ,Blood Component Transfusion ,Time-to-Treatment ,Cohort Studies ,MULTIPLE IMPUTATION ,DOUBLE-BLIND ,Plasma ,PROPENSITY SCORE ANALYSIS ,SDG 3 - Good Health and Well-being ,medicine ,Coagulopathy ,MANAGEMENT ,Humans ,Original Investigation ,FIBRINOGEN CONCENTRATE ,COAGULOPATHY ,Hysterectomy ,business.industry ,Obstetrics ,Incidence (epidemiology) ,Research ,Incidence ,Postpartum Hemorrhage ,HOSPITAL CARDIAC-ARREST ,Obstetrics and Gynecology ,TRANEXAMIC ACID ,General Medicine ,Odds ratio ,Puerperal Disorders ,medicine.disease ,Uterine atony ,Online Only ,BALANCE ,Propensity score matching ,Female ,business ,Cohort study - Abstract
This cohort study examines the association of timing of receipt of plasma transfusions among women experiencing persistent postpartum hemorrhage with adverse maternal outcomes., Key Points Question Is plasma transfusion within the first 60 minutes of persistent postpartum hemorrhage (PPH) associated with incidence of maternal adverse outcomes? Findings In this cohort study of 114 propensity score–matched women with persistent PPH, plasma transfusion within the first 60 minutes of persistent PPH was not associated with incidence of maternal adverse outcomes compared with no or later plasma transfusion, independent of severity of PPH at the time of plasma transfusion. Meaning These findings do not support the theory that early plasma transfusion in women with persistent PPH is better than no or later plasma transfusion., Importance Early plasma transfusion for women with severe postpartum hemorrhage (PPH) is recommended to prevent coagulopathy. However, there is no comparative, quantitative evidence on the association of early plasma transfusion with maternal outcomes. Objective To compare the incidence of adverse maternal outcomes among women who received plasma during the first 60 minutes of persistent PPH vs women who did not receive plasma for similarly severe persistent PPH. Design, Setting, and Participants This multicenter cohort study used a consecutive sample of women with persistent PPH, defined as PPH refractory to first-line measures to control bleeding, between January 1, 2011, and January 1, 2013. Time-dependent propensity score matching was used to select women who received plasma during the first 60 minutes of persistent PPH and match each of them with a woman who had shown the same severity and received the same treatment of PPH but who had not received plasma at the moment of matching. Transfusions were not guided by coagulation tests. Statistical analysis was performed from June 2018 to June 2019. Exposures Transfusion of plasma during the first 60 minutes of persistent PPH vs no or later plasma transfusion. Main Outcomes and Measures Incidence of adverse maternal outcomes, defined as a composite of death, hysterectomy, or arterial embolization. Results This study included 1216 women (mean [SD] age, 31.6 [5.0] years) with persistent PPH, of whom 932 (76.6%) delivered vaginally and 780 (64.1%) had PPH caused by uterine atony. Seven women (0.6%) died because of PPH, 62 women (5.1%) had a hysterectomy, and 159 women (13.1%) had arterial embolizations. Among women who received plasma during the first 60 minutes of persistent PPH, 114 women could be matched with a comparable woman who had not received plasma at the moment of matching. The incidence of adverse maternal outcomes was similar between the women, with adverse outcomes recorded in 24 women (21.2%) who received early plasma transfusion and 23 women (19.9%) who did not receive early plasma transfusion (odds ratio, 1.09; 95% CI, 0.57-2.09). Results of sensitivity analyses were comparable to the primary results. Conclusions and Relevance In this cohort study, initiation of plasma transfusion during the first 60 minutes of persistent PPH was not associated with adverse maternal outcomes compared with no or later plasma transfusion, independent of severity of PPH.
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- 2019
- Full Text
- View/download PDF
19. Clinical characteristics of women captured by extending the definition of severe postpartum haemorrhage with ‘refractoriness to treatment’: a cohort study
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Henriquez, D.D.C.A., Gillissen, A., Smith, S.M., Cramer, R.A., Akker, T. van den, Zwart, J.J., Roosmalen, J.J.M. van, Bloemenkamp, K.W.M., Bom, J.G. van der, Adriaanse, H.J., Akker, E.S.A. van den, Baas, M.I., Bank, C.M.C., Beek, E. van, Boer, B.A. de, Boer, K. de, Borden, D.M.R. van der, Bremer, H.A., Brons, J.T.J., Burggraaff, J.M., Ceelie, H., Chon, H., Cikot, J.L.M., Delemarre, F.M.C., Diris, J.H.C., Doesburg-van Kleffens, M., Dooren, I.M.A. van, Duijnhoven, J.L.P. van, Dunn, F.M. van, Duvekot, J.J., Engbers, P., Etten-van Hulst, M.J.W. van, Feitsma, H., Fouraux, M.A., Franssen, M.T.M., Frasa, M.A.M., Gammeren, A.J. van, Gemund, N. van, Graaf, F. van der, Groot, C.J.M. de, Hackeng, C.M., Ham, D.P. van der, Hanssen, M.J.C.P., Hasaart, T.H.M., Hendriks, H.A., Henskens, Y.M.C., Hermsen, B.B.J., Hogenboom, S., Hooker, A., Hudig, F., Huijssoon, A.M.G., Huisjes, A.J.M., Jonker, N., Kabel, P.J., Kampen, C. van, Keijzer, M.H. de, Kerkhof, D.H. van de, Keuren, J.F.W., Kleiverda, G., Klinkspoor, J.H., Koehorst, S.G.A., Kok, M., Kok, R.D., Kok, J.B. de, Koops, A., Kortlandt, W., Langenveld, J., Leers, M.P.G., Leyte, A., Mare, A. de, Martens, G.D.M., Meekers, J.H., Meir, C.A. van, Metz, G.C.H., Michielse, E.C.H.J., Mostert, L.J., Bijvank, S.W.H.N., Oostenveld, E., Osmanovic, N., Oudijk, M.A., Mirani-Oostdijk, C.P., Pampus, E.C.M. van, Papatsonis, D.N.M., Peters, R.H.M., Ponjee, G.A.E., Pontesilli, M., Porath, M.M., Post, M.S., Pouwels, J.G.J., Prinzen, L., Roelofsen, J.M.T., Rondeel, J.J.M., Salm, P.C.M. van der, Scheepers, H.C.J., Schippers, D.H., Schuitemaker, N.W.E., Sikkema, J.M., Slomp, J., Smit, J.W., Snuif-de Lange, Y.S., Stappen, J.W.J. van der, Steures, P., Tax, G.H.M., Treskes, M., Ulenkate, H.J.L.M., Unnik, G.A. van, Veen, B.S. van der, Verhagen, T.E.M., Versendaal, J., Visschers, B., Visser, O., Visser, H., Vooght, K.M.K. de, Vries, M.J. de, Waard, H. de, Weerkamp, F., Weinans, M.J.N., Wet, H. de, Wijnen, M. van, Wijngaarden, W.J. van, Wit, A.C. de, Woiski, M.D., TeMpOH-1 Study Grp, Obstetrics & Gynecology, Science Communication, APH - Global Health, Athena Institute, APH - Quality of Care, Reproductive Origins of Adult Health and Disease (ROAHD), Ethics, Law & Medical humanities, Cardiology, ACS - Heart failure & arrhythmias, Obstetrics and gynaecology, Amsterdam Reproduction & Development (AR&D), Pediatric surgery, Hematology, Faculteit FHML Centraal, RS: CARIM - R1.04 - Clinical thrombosis and haemostasis, MUMC+: DA CDL Algemeen (9), RS: GROW - R4 - Reproductive and Perinatal Medicine, MUMC+: MA Medische Staf Obstetrie Gynaecologie (9), Obstetrie & Gynaecologie, and RS: Carim - B04 Clinical thrombosis and Haemostasis
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Male ,Blood transfusion ,Refractory period ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,Severity of Illness Index ,law.invention ,Postpartum haemorrhage ,0302 clinical medicine ,law ,Pregnancy ,Risk Factors ,Netherlands ,030219 obstetrics & reproductive medicine ,Obstetrics ,Incidence ,Obstetrics and Gynecology ,Prognosis ,Intensive care unit ,Embolization, Therapeutic ,PREVALENCE ,Survival Rate ,Female ,Cohort study ,Research Article ,Maternal mortality ,Adult ,medicine.medical_specialty ,Reproductive medicine ,Other Research Radboud Institute for Molecular Life Sciences [Radboudumc 0] ,Hysterectomy ,lcsh:Gynecology and obstetrics ,03 medical and health sciences ,All institutes and research themes of the Radboud University Medical Center ,SDG 3 - Good Health and Well-being ,medicine ,Humans ,Blood Transfusion ,lcsh:RG1-991 ,Retrospective Studies ,SEVERE MATERNAL MORBIDITY ,business.industry ,Other Research Radboud Institute for Health Sciences [Radboudumc 0] ,Postpartum Hemorrhage ,Infant, Newborn ,Retrospective cohort study ,Definition ,Packed red blood cells ,business ,Maternal morbidity ,Follow-Up Studies - Abstract
Background The absence of a uniform and clinically relevant definition of severe postpartum haemorrhage hampers comparative studies and optimization of clinical management. The concept of persistent postpartum haemorrhage, based on refractoriness to initial first-line treatment, was proposed as an alternative to common definitions that are either based on estimations of blood loss or transfused units of packed red blood cells (RBC). We compared characteristics and outcomes of women with severe postpartum haemorrhage captured by these three types of definitions. Methods In this large retrospective cohort study in 61 hospitals in the Netherlands we included 1391 consecutive women with postpartum haemorrhage who received either ≥4 units of RBC or a multicomponent transfusion. Clinical characteristics and outcomes of women with severe postpartum haemorrhage defined as persistent postpartum haemorrhage were compared to definitions based on estimated blood loss or transfused units of RBC within 24 h following birth. Adverse maternal outcome was a composite of maternal mortality, hysterectomy, arterial embolisation and intensive care unit admission. Results One thousand two hundred sixty out of 1391 women (90.6%) with postpartum haemorrhage fulfilled the definition of persistent postpartum haemorrhage. The majority, 820/1260 (65.1%), fulfilled this definition within 1 h following birth, compared to 819/1391 (58.7%) applying the definition of ≥1 L blood loss and 37/845 (4.4%) applying the definition of ≥4 units of RBC. The definition persistent postpartum haemorrhage captured 430/471 adverse maternal outcomes (91.3%), compared to 471/471 (100%) for ≥1 L blood loss and 383/471 (81.3%) for ≥4 units of RBC. Persistent postpartum haemorrhage did not capture all adverse outcomes because of missing data on timing of initial, first-line treatment. Conclusion The definition persistent postpartum haemorrhage identified women with severe postpartum haemorrhage at an early stage of haemorrhage, unlike definitions based on blood transfusion. It also captured a large majority of adverse maternal outcomes, almost as large as the definition of ≥1 L blood loss, which is commonly applied as a definition of postpartum haemorrhage rather than severe haemorrhage.
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20. Fluid resuscitation during persistent postpartum haemorrhage and maternal outcome: A nationwide cohort study
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Henriquez, D.D.C.A., Bloemenkamp, K.W.M., Loeff, R.M., Zwart, J.J., Roosmalen, J.J.M. van, Zwaginga, J.J., Bom, J.G. van der, Adriaanse, H.J., Akker, E.S.A. van den, Baas, M.I., Bank, C.M.C., Beek, E. van, Boer, B.A. de, Boer, K. de, Borden, D.M.R. van der, Bremer, H.A., Brons, J.T.J., Burggraaff, J.M., Ceelie, H., Chon, H., Cikot, J.L.M., Delemarre, F.M.C., Diris, J.H.C., Doesburg-van Kleffens, M., Dooren, I.M.A. van, Duijnhoven, J.L.P. van, Dunne, F.M. van, Duvekot, J.J., Engbers, P., Hulst, M.J.W.V., Feitsma, H., Fouraux, M.A., Franssen, M.T.M., Frasa, M.A.M., Gammeren, A.J. van, Gemund, N. van, Graaf, F. van der, Groot, C.J.M. de, Hackeng, C.M., Ham, D.P. van der, Hanssen, M.J.C.P., Hasaart, T.H.M., Hendriks, H.A., Henskens, Y.M.C., Hermsen, B.B.J., Hogenboom, S., Hooker, A., Hudig, F., Huijssoon, A.M.G., Huisjes, A.J.M., Jonker, N., Kabel, P.J., Kampen, C. van, Keijzer, M.H. de, Kerkhof, D.H. van de, Keuren, J.F.W., Kleiverda, G., Klinkspoor, J.H., Koehorst, S.G.A., Kok, M., Kok, R.D., Kok, J.B. de, Koops, A., Kortlandt, W., Langenveld, J., Leers, M.P.G., Leyte, A., Mare, A. de, Martens, G.D.M., Meekers, J.H., Meir, C.A. van, Metz, G.C.H., Michielse, E.C.H.J., Mostert, L.J., Bijvank, S.W.H.N., Oostenveld, E., Osmanovic, N., Oudijk, M.A., Mirani-Oostdijk, C.P., Pampus, E.C.M. van, Papatsonis, D.N.M., Peters, R.H.M., Ponjee, G.A.E., Pontesilli, M., Porath, M.M., Post, M.S., Pouwels, J.G.J., Prinzen, L., Roelofsen, J.M.T., Rondeel, J.J.M., Salm, P.C.M. van der, Scheepers, H.C.J., Schippers, D.H., Schuitemaker, N.W.E., Sikkema, J.M., Slomp, J., Smit, J.W., Snuif-de Lange, Y.S., Stappen, J.W.J. van der, Steures, P., Tax, G.H.M., Treskes, M., Ulenkate, H.J.L.M., Unnik, G.A. van, Veen, B.S. van der, Verhagen, T.E.M., Versendaal, J., Visschers, B., Visser, O., Visser, H., Vooght, K.M.K. de, Vries, M.J. de, Waard, H. de, Weerkamp, F., Weinans, M.J.N., Wet, H. de, Wijnen, M. van, Wijngaarden, W.J. van, Wit, A.C. de, Woiski, M.D., TeMpOH-Study Grp, APH - Quality of Care, APH - Global Health, Obstetrics & Gynecology, RS: CARIM - R1.04 - Clinical thrombosis and haemostasis, MUMC+: DA CDL Algemeen (9), Faculteit FHML Centraal, RS: Carim - B04 Clinical thrombosis and Haemostasis, Reproductive Origins of Adult Health and Disease (ROAHD), and Athena Institute
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Adult ,medicine.medical_specialty ,Resuscitation ,Blood transfusion ,medicine.medical_treatment ,CRYSTALLOIDS ,Postpartum haemorrhage ,03 medical and health sciences ,RED-BLOOD-CELLS ,0302 clinical medicine ,SDG 3 - Good Health and Well-being ,Interquartile range ,Pregnancy ,ERYTHROCYTES ,medicine ,Humans ,Crystalloid solutions ,030212 general & internal medicine ,Colloids ,THROMBIN GENERATION ,Netherlands ,Retrospective Studies ,COAGULOPATHY ,030219 obstetrics & reproductive medicine ,Obstetrics ,business.industry ,Postpartum Hemorrhage ,Obstetrics and Gynecology ,Retrospective cohort study ,Odds ratio ,Confidence interval ,Treatment Outcome ,Reproductive Medicine ,Fluid Therapy ,TRAUMA PATIENTS ,Female ,Packed red blood cells ,business ,Cohort study - Abstract
Objective: To determine the association between increasing volumes of crystalloids and colloids administered before transfusion of packed red blood cells in women with persistent postpartum haemorrhage and adverse maternal outcomes. Study design: Retrospective cohort study in the Netherlands. Women with persistent postpartum haemorrhage and known clear fluids volume for resuscitation were included. Women who received ≤2 L of clear fluids were the reference group. We determined the effect of every additional litre of clear fluids on total blood loss, severe maternal morbidity and mortality. Results were adjusted for patient and bleeding characteristics. Results: Of the 883 included women, 199 received ≤2 L of clear fluids. Median blood loss for the reference group was 2.9 L (interquartile range 2.2–3.4). Adjusted mean difference in blood loss compared with the reference group was 0.2 L (95% confidence interval −0.1 to 0.5) for women in the >2 to ≤3 L, 0.4 L (0.1–0.7) for the >3 to ≤4 L category, 0.6 L (0.5–0.7) for the >4 to ≤5 L category, and 1.9 L (1.5–2.3) for the >5 to ≤7 L category. Adjusted odds ratios for adverse maternal outcomes were 1.0 (0.7–1.6), 1.2 (0.8–1.9), 1.8 (1.1–3.1) and 4.4 (2.6–7.5) for women in the 2 to ≤3 L category, >3 to ≤4 L, >4 to ≤5 L, and >5 to ≤7 L volume categories respectively. Results were similar in strata of different severities of bleeding. Conclusion: Clear fluids volume >4 L was independently associated with adverse maternal outcome in women with persistent postpartum haemorrhage.
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21. The Duality of Lean: Organizational Learning for Sustained Development
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Knol, W.H., Lauche, K., Schouteten, R.L.J., and Slomp, J.
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22. Pathways to develop a lean organization: configurations of lean practices for different business strategies
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Knol, W.H. and Slomp, J.
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23. Nature and origin of the neointima in whole vessel wall organ culture of the human saphenous vein
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Slomp, J., Gittenberger-de Groot, A. C., van Munsteren, J. C., Poelmann, R. E., Huysmans, H. A., van Bockel, J. H., and van Hinsbergh, V. W. M.
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24. The relative importance of improvement routines for implementing lean practices
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Knol, W.H., Slomp, J., Schouteten, R.L.J., Lauche, K., Knol, W.H., Slomp, J., Schouteten, R.L.J., and Lauche, K.
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03 oktober 2018, Contains fulltext : 201668.pdf (publisher's version ) (Open Access)
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25. Immunophenotypic measurable residual disease (MRD) in acute myeloid leukemia: Is multicentric MRD assessment feasible?
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Brooimans, Rik A., Velden, V.H. van der, Boeckx, N., Slomp, J., Preijers, F.W., Marvelde, Jeroen G. te, Kelder, A., Schuurhuis, G.J., Brooimans, Rik A., Velden, V.H. van der, Boeckx, N., Slomp, J., Preijers, F.W., Marvelde, Jeroen G. te, Kelder, A., and Schuurhuis, G.J.
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Contains fulltext : 201053.pdf (publisher's version ) (Open Access)
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26. Clinical characteristics of women captured by extending the definition of severe postpartum haemorrhage with 'refractoriness to treatment': a cohort study
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Henriquez, D., Gillissen, A., Smith, S.M., Cramer, R.A., van den Akker, T., Zwart, J.J. (Joost), van Roosmalen, J.J., Bloemenkamp, KW, Bom, J.G., Adriaanse, H.J., van den Akker, E.S.A., Baas, M.I., Bank, C.M.C., Beek, E. van, de Boer, B.A.G., Boer, K. (Karin), van der Borden, D.M.R., Bremer, H.A. (Henk), Brons, J.T.J., Burggraaff, J.M. (Jan), Ceelie, H., Chon, H., Cikot, J.L.M., Delemarre, F.M.C., Diris, J.H.C., Doesburg-van Kleffens, M., van Dooren, I.M.A., van Duijnhoven, J.L.P., van Dunn, F.M., Duvekot, J.J. (Hans), Engbers, P., van Hulst, M.J.W., Feitsma, H., Fouraux, M.A., Franssen, MT, Frasa, M.A.M., van Gammeren, A.J., Gemund, N. (Nicolette) van, van der Graaf, F., Groot, C.J.M., Hackeng, C.M. (Christian), Ham, D.P. (David) van der, Hanssen, M., Hasaart, T.H.M. (Tom), Hendriks, H.A., Henskens, Y.M.C., Hermsen, B.B.J., Hogenboom, S., Hooker, A., Hudig, F, Huijssoon, A.G. (Annemarie), Huisjes, A.J.M. (Anjoke), Jonker, N., Kabel, P.J., van Kampen, C., de Keijzer, M.H., van de Kerkhof, D.H., Keuren, JFW, Kleiverda, G., Klinkspoor, J.H., Koehorst, S.G.A., Kok, M.O. (Maarten), Kok, R.D., Kok, J.B. (Jacques) de, Koops, A., Kortlandt, W. (Wouter), Langenveld, J. (J.), Leers, MPG, Leyte, A. (Anja), de Mare, A., Martens, G.D.M., Meekers, J.H., Meir, C.A. (Claudia) van, Metz, G.C.H. (Godfried), Michielse, E., Mostert, L.J., Bijvank, S., Oostenveld, E., Osmanovic, N., Oudijk, M.A. (Martijn), Mirani-Oostdijk, C.P., van Pampus, E. C. M., Papatsonis, D.N.M. (Dimitri), Peters, R.H.M., Ponjee, G.A.E. (Gabriëlle), Pontesilli, M., Porath, M. (Martina), Post, M.S., Pouwels, J.G.J., Prinzen, L., Roelofsen, J.M.T., Rondeel, J.J.M., Salm, P.C.M. (Paulien) van der, Scheepers, H.C.J. (Hubertina), Schippers, D.H. (Daniela), Schuitemaker, N.W.E. (Nico), Sikkema, J.M. (J. Marko), Slomp, J. (Jennita), Smit, J.W.A. (Jan), Snuif-de Lange, Y.S., van der Stappen, J.W.J., Steures, P. (Pieternel), Tax, G.H.M., Treskes, M., Ulenkate, H., van Unnik, G.A., van der Veen, B.S., Verhagen, T.E.M., Versendaal, J. (Johan), Visschers, B., Visser, O. (Oane), de Visser, H., De Vooght, KMK, de Vries, M.J., Waard, H. (Harm) de, Weerkamp, F. (Floor), Weinans, M.J.N. (Martin), de Wet, H., Wijnen, M. (Marit), Wijngaarden, W.J. (Wim) van, de Wit, A.C., Woiski, M.D. (Mallory), TeMp, O.H.S.G., Henriquez, D., Gillissen, A., Smith, S.M., Cramer, R.A., van den Akker, T., Zwart, J.J. (Joost), van Roosmalen, J.J., Bloemenkamp, KW, Bom, J.G., Adriaanse, H.J., van den Akker, E.S.A., Baas, M.I., Bank, C.M.C., Beek, E. van, de Boer, B.A.G., Boer, K. (Karin), van der Borden, D.M.R., Bremer, H.A. (Henk), Brons, J.T.J., Burggraaff, J.M. (Jan), Ceelie, H., Chon, H., Cikot, J.L.M., Delemarre, F.M.C., Diris, J.H.C., Doesburg-van Kleffens, M., van Dooren, I.M.A., van Duijnhoven, J.L.P., van Dunn, F.M., Duvekot, J.J. (Hans), Engbers, P., van Hulst, M.J.W., Feitsma, H., Fouraux, M.A., Franssen, MT, Frasa, M.A.M., van Gammeren, A.J., Gemund, N. (Nicolette) van, van der Graaf, F., Groot, C.J.M., Hackeng, C.M. (Christian), Ham, D.P. (David) van der, Hanssen, M., Hasaart, T.H.M. (Tom), Hendriks, H.A., Henskens, Y.M.C., Hermsen, B.B.J., Hogenboom, S., Hooker, A., Hudig, F, Huijssoon, A.G. (Annemarie), Huisjes, A.J.M. (Anjoke), Jonker, N., Kabel, P.J., van Kampen, C., de Keijzer, M.H., van de Kerkhof, D.H., Keuren, JFW, Kleiverda, G., Klinkspoor, J.H., Koehorst, S.G.A., Kok, M.O. (Maarten), Kok, R.D., Kok, J.B. (Jacques) de, Koops, A., Kortlandt, W. (Wouter), Langenveld, J. (J.), Leers, MPG, Leyte, A. (Anja), de Mare, A., Martens, G.D.M., Meekers, J.H., Meir, C.A. (Claudia) van, Metz, G.C.H. (Godfried), Michielse, E., Mostert, L.J., Bijvank, S., Oostenveld, E., Osmanovic, N., Oudijk, M.A. (Martijn), Mirani-Oostdijk, C.P., van Pampus, E. C. M., Papatsonis, D.N.M. (Dimitri), Peters, R.H.M., Ponjee, G.A.E. (Gabriëlle), Pontesilli, M., Porath, M. (Martina), Post, M.S., Pouwels, J.G.J., Prinzen, L., Roelofsen, J.M.T., Rondeel, J.J.M., Salm, P.C.M. (Paulien) van der, Scheepers, H.C.J. (Hubertina), Schippers, D.H. (Daniela), Schuitemaker, N.W.E. (Nico), Sikkema, J.M. (J. Marko), Slomp, J. (Jennita), Smit, J.W.A. (Jan), Snuif-de Lange, Y.S., van der Stappen, J.W.J., Steures, P. (Pieternel), Tax, G.H.M., Treskes, M., Ulenkate, H., van Unnik, G.A., van der Veen, B.S., Verhagen, T.E.M., Versendaal, J. (Johan), Visschers, B., Visser, O. (Oane), de Visser, H., De Vooght, KMK, de Vries, M.J., Waard, H. (Harm) de, Weerkamp, F. (Floor), Weinans, M.J.N. (Martin), de Wet, H., Wijnen, M. (Marit), Wijngaarden, W.J. (Wim) van, de Wit, A.C., Woiski, M.D. (Mallory), and TeMp, O.H.S.G.
- Abstract
Background: The absence of a uniform and clinically relevant definition of severe postpartum haemorrhage hampers comparative studies and optimization of clinical management. The concept of persistent postpartum haemorrhage, based on refractoriness to initial first-line treatment, was proposed as an alternative to common definitions that are either based on estimations of blood loss or transfused units of packed red blood cells (RBC). We compared characteristics and outcomes of women with severe postpartum haemorrhage captured by these three types of definitions. Methods: In this large retrospective cohort study in 61 hospitals in the Netherlands we included 1391 consecutive women with postpartum haemorrhage who received either ≥4 units of RBC or a multicomponent transfusion. Clinical characteristics and outcomes of women with severe postpartum haemorrhage defined as persistent postpartum haemorrhage were compared to definitions based on estimated blood loss or transfused units of RBC within 24 h following birth. Adverse maternal outcome was a composite of maternal mortality, hysterectomy, arterial embolisation and intensive care unit admission. Results: One thousand two hundred sixty out of 1391 women (90.6%) with postpartum haemorrhage fulfilled the definition of persistent postpartum haemorrhage. The majority, 820/1260 (65.1%), fulfilled this definition within 1 h following birth, compared to 819/1391 (58.7%) applying the definition of ≥1 L blood loss and 37/845 (4.4%) applying the definition of ≥4 units of RBC. The definition persistent postpartum haemorrhage captured 430/471 adverse maternal outcomes (91.3%), compared to 471/471 (100%) for ≥1 L blood loss and 383/471 (81.3%) for ≥4 units of RBC. Persiste
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27. Immunophenotypic measurable residual disease (MRD) in acute myeloid leukemia: Is multicentric MRD assessment feasible?
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Brooimans, R.A. (Rik), Velden, V.H.J. (Vincent) van der, Boeckx, N. (Nancy), Slomp, J. (Jennita), Preijers, F.W.M.B. (Frank), Marvelde, J.G. (Jeroen) te, Van, N.M. (Ngoc M.), Heijs, A. (Antoinette), Huys, E. (Erik), Holt, B. (Bronno) van der, Greef, G.E. (Georgine) de, Kelder, A. (Angele), Schuurhuis, G.J. (Gerrit Jan), Brooimans, R.A. (Rik), Velden, V.H.J. (Vincent) van der, Boeckx, N. (Nancy), Slomp, J. (Jennita), Preijers, F.W.M.B. (Frank), Marvelde, J.G. (Jeroen) te, Van, N.M. (Ngoc M.), Heijs, A. (Antoinette), Huys, E. (Erik), Holt, B. (Bronno) van der, Greef, G.E. (Georgine) de, Kelder, A. (Angele), and Schuurhuis, G.J. (Gerrit Jan)
- Abstract
Flow-cytometric detection of now termed measurable residual disease (MRD) in acute myeloid leukemia (AML) has proven to have an independent prognostic impact. In a previous multicenter study we developed protocols to accurately define leukemia-associated immunophenotypes (LAIPs) at diagnosis. It has, however, not been demonstrated whether the use of the defined LAIPs in the same multicenter setting results in a high concordance between centers in MRD assessment. In the present paper we evaluated whether interpretation of list-mode data (LMD) files, obtained from MRD assessment of previously determined LAIPs during and after treatment, could reliably be performed in a multicenter setting. The percentage of MRD positive cells was simultaneously determined in totally 173 LMD files from 77 AML patients by six participating centers. The quantitative concordance between the six participating centers was meanly 84%, with slight variation of 75%–89%. In addition our data showed that the type and number of LAIPs were of influence on the performance outcome. The highest concordance was observed for LAIPs with cross-lineage expression, followed by LAIPs with an asynchronous antigen expression. Our results imply that immunophenotypic MRD assessment in AML will only be feasible when fully standardized methods are used for reliable multicenter assessment.
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28. Clinical characteristics of women captured by extending the definition of severe postpartum haemorrhage with 'refractoriness to treatment': a cohort study
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Henriquez, D, Gillissen, A, Smith, SM, Cramer, RA, van den Akker, T, Zwart, JJ, van Roosmalen, JJ, Bloemenkamp, KW, Bom, JG, Adriaanse, HJ, Akker, ESA, Baas, MI, Bank, CMC, Beek, E, de Boer, BAG, Boer, K, van der Borden, DMR, Bremer, HA, Brons, JTJ, Burggraaff, JM, Ceelie, H, Chon, H, Cikot, JLM, Delemarre, FMC, Diris, JHC, Doesburg-van Kleffens, M, van Dooren, IMA, van Duijnhoven, JLP, van Dunn, FM, Duvekot, J.J., Engbers, P, Hulst, MJW, Feitsma, H, Fouraux, MA, Franssen, MT, Frasa, MAM, van Gammeren, AJ, Gemund, N, Graaf, F, Groot, CJM, Hackeng, CM, van der Ham, DP, Hanssen, M, Hasaart, THM, Hendriks, HA, Henskens, YMC, Hermsen, BBJ, Hogenboom, S, Hooker, A, Hudig, F, Huijssoon, AMG, Huisjes, AJM, Jonker, N, Kabel, PJ, van Kampen, C, de Keijzer, MH, van de Kerkhof, DH, Keuren, JFW, Kleiverda, G, Klinkspoor, JH, Koehorst, SGA, Kok, M, Kok, RD, de Kok, JB, Koops, A, Kortlandt, W, Langenveld, J, Leers, MPG, Leyte, A, de Mare, A, Martens, GDM, Meekers, JH, van Meir, CA, Metz, GCH, Michielse, E, Mostert, LJ, Bijvank, S, Oostenveld, E, Osmanovic, N, Oudijk, MA, Mirani-Oostdijk, CP, van Pampus, E C M, Papatsonis, DNM, Peters, RHM, Ponjee, GA, Pontesilli, M, Porath, MM, Post, MS, Pouwels, JGJ, Prinzen, L, Roelofsen, JMT, Rondeel, JJM, van der Salm, PCM, Scheepers, HCJ, Schippers, DH, Schuitemaker, NWE, Sikkema, JM, Slomp, J, Smit, JWA, Snuif-de Lange, YS, van der Stappen, JWJ, Steures, P, Tax, GHM, Treskes, M, Ulenkate, H, van Unnik, GA, van der Veen, BS, Verhagen, TEM, Versendaal, J, Visschers, B, Visser, O, Visser, H, De Vooght, KMK, Vries, MJ, Waard, H, Weerkamp, F, Weinans, MJN, de Wet, H, Wijnen, M (Mandy), van Wijngaarden, WJ, de Wit, AC, Woiski, MD, TeMp, OHSG, Henriquez, D, Gillissen, A, Smith, SM, Cramer, RA, van den Akker, T, Zwart, JJ, van Roosmalen, JJ, Bloemenkamp, KW, Bom, JG, Adriaanse, HJ, Akker, ESA, Baas, MI, Bank, CMC, Beek, E, de Boer, BAG, Boer, K, van der Borden, DMR, Bremer, HA, Brons, JTJ, Burggraaff, JM, Ceelie, H, Chon, H, Cikot, JLM, Delemarre, FMC, Diris, JHC, Doesburg-van Kleffens, M, van Dooren, IMA, van Duijnhoven, JLP, van Dunn, FM, Duvekot, J.J., Engbers, P, Hulst, MJW, Feitsma, H, Fouraux, MA, Franssen, MT, Frasa, MAM, van Gammeren, AJ, Gemund, N, Graaf, F, Groot, CJM, Hackeng, CM, van der Ham, DP, Hanssen, M, Hasaart, THM, Hendriks, HA, Henskens, YMC, Hermsen, BBJ, Hogenboom, S, Hooker, A, Hudig, F, Huijssoon, AMG, Huisjes, AJM, Jonker, N, Kabel, PJ, van Kampen, C, de Keijzer, MH, van de Kerkhof, DH, Keuren, JFW, Kleiverda, G, Klinkspoor, JH, Koehorst, SGA, Kok, M, Kok, RD, de Kok, JB, Koops, A, Kortlandt, W, Langenveld, J, Leers, MPG, Leyte, A, de Mare, A, Martens, GDM, Meekers, JH, van Meir, CA, Metz, GCH, Michielse, E, Mostert, LJ, Bijvank, S, Oostenveld, E, Osmanovic, N, Oudijk, MA, Mirani-Oostdijk, CP, van Pampus, E C M, Papatsonis, DNM, Peters, RHM, Ponjee, GA, Pontesilli, M, Porath, MM, Post, MS, Pouwels, JGJ, Prinzen, L, Roelofsen, JMT, Rondeel, JJM, van der Salm, PCM, Scheepers, HCJ, Schippers, DH, Schuitemaker, NWE, Sikkema, JM, Slomp, J, Smit, JWA, Snuif-de Lange, YS, van der Stappen, JWJ, Steures, P, Tax, GHM, Treskes, M, Ulenkate, H, van Unnik, GA, van der Veen, BS, Verhagen, TEM, Versendaal, J, Visschers, B, Visser, O, Visser, H, De Vooght, KMK, Vries, MJ, Waard, H, Weerkamp, F, Weinans, MJN, de Wet, H, Wijnen, M (Mandy), van Wijngaarden, WJ, de Wit, AC, Woiski, MD, and TeMp, OHSG
- Published
- 2019
29. Immunophenotypic measurable residual disease (MRD) in acute myeloid leukemia: Is multicentric MRD assessment feasible?
- Author
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Brooimans, Rik, van der Velden, Vincent, Boeckx, N, Slomp, J, Preijers, F, te Marvelde, Jeroen, Van, Mai, Heijs, A, Huys, E, van der Holt, Ronnie, Greef, Georgine, Kelder, A, Schuurhuis, GJ, Brooimans, Rik, van der Velden, Vincent, Boeckx, N, Slomp, J, Preijers, F, te Marvelde, Jeroen, Van, Mai, Heijs, A, Huys, E, van der Holt, Ronnie, Greef, Georgine, Kelder, A, and Schuurhuis, GJ
- Published
- 2019
30. On the synergy between smart industry technologies and lean principles
- Author
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Bokhorst, J.A.C., Knol, W.H., and Slomp, J.
- Published
- 2018
31. The sociotechnical success factors of POLCA, Appendix E
- Author
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Slomp, J. and Suri, Rajan
- Published
- 2018
32. Implementing lean practices in manufacturing SMEs: testing ‘critical success factors’ using Necessary Condition Analysis
- Author
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Knol, W.H., Slomp, J., Schouteten, R.L.J., Lauche, K., Knol, W.H., Slomp, J., Schouteten, R.L.J., and Lauche, K.
- Abstract
09 januari 2018, Contains fulltext : 195215.pdf (publisher's version ) (Open Access), Lean practices are known to increase operational performance. Previous research has identified critical success factors for implementing lean practices. This research aims to examine the extent to which success factors are critical for various degrees of lean practice implementation. Using multiple-respondent self-assessments from 33 Dutch manufacturing small and medium-sized enterprises (SMEs), we conducted a Necessary Condition Analysis. Our findings indicated that the criticality of success factors is progression dependent. In the initial stages of the lean journey, SMEs could improve their lean practices in a bottom-up manner through local factors such as a learning focus, improvement training and support congruence. When lean practices are more advanced, some company-wide factors must be present: top management support, a shared improvement vision and a supplier link. Our findings question the universality of success factors such as strategic involvement and indicate the need for a more dynamic model of lean implementation.
- Published
- 2018
33. LEUKEMIC STEM CELL FREQUENCY COMBINED WITH MRD IS AN IMPORTANT BIOMARKER TO PREDICT RELAPSE IN ACUTE MYELOID LEUKEMIA. RESULTS FROM A PROSPECTIVE H102 STUDY
- Author
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Zeijlemaker, W., Meijer, R., Kelder, A., Carbaat-Ham, J., Oussoren-brockhoff, Y., Snel, S., Veldhuizen, D., Scholten, W., Maertens, J., Breems, D., Pabst, T., Manz, M., Van der Velden, V., Slomp, J., Valk, P., Cloos, J., Lowenberg, B., Ossenkoppele, G., Schuurhuis, G. J., CCA - Imaging and biomarkers, Hematology laboratory, and Hematology
- Published
- 2017
34. Performance evaluation of family-based dispatching in small manufacturing cells.
- Author
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Bokhorst, J. A. C., Nomden, G., and Slomp, J.
- Subjects
FLEXIBLE manufacturing systems ,SELF-service (Economics) ,MANUFACTURING cells ,MANUFACTURING processes ,ASSEMBLY line methods ,FACTORY management - Abstract
In many practical instances, the choice of whether to apply family-based dispatching or not can be decided per machine. The present paper explores the impact of the location of family-based dispatching, load variations between machines and routing of jobs on the flow time effect of family-based dispatching. These factors are explored in small manufacturing cells with and without labour constraints. An industrial case motivates the study. A simulation study is performed to assess the impact of these effects. The results show that shop-floor characteristics such as routing and load variation impact the decision where to locate family-based dispatching in manufacturing cells without labour constraints. By contrast, the effect of family-based dispatching is much less vulnerable to shop-floor characteristics in cells with labour constraints. Since workers are the bottleneck in these cells, it becomes less important at what machine the set-up time involving a worker is reduced. In general, there seems to be a trade-off between the positive effect of applying family-based dispatching at a (bottleneck) machine and the possible negative effect of the more irregular job arrivals at subsequent machines. The results further indicate that family-based dispatching is more advantageous in cells with labour constraints than in cells without labour constraints, when both types of manufacturing cells have comparable machine utilizations. [ABSTRACT FROM AUTHOR]
- Published
- 2008
- Full Text
- View/download PDF
35. Worker flexibility in a parallel dual resource constrained job shop.
- Author
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Yue, H., Slomp, J., Molleman, E., and Van Der Zee, D. J.
- Subjects
EMPLOYEE training ,MANUFACTURING cells ,FLEXIBLE manufacturing systems ,LEARNING curve ,EXPERIENCE curve ,LABOR productivity - Abstract
In this paper we investigate cross-training policies in a dual resource constraint (DRC) parallel job shop where new part types are frequently introduced into the system. Each new part type introduction induces the need for workers to go through a learning curve. A cross-training policy relates to the level of multi-functionality, the pattern of skill overlaps, and the distribution of skills among workers. Our results show that the frequency of new part type introduction needs to be considered when selecting a cross-training policy. The frequency of new part type introduction has impact on the optimal level of cross-training, the relative advantage of skill overlaps, and the extent to which a cross-training policy should incorporate differences between workers. These findings are important for many DRC job shops, especially for manufacturing cells in which all changes, associated with a part type introduction, are concentrated in one cell. [ABSTRACT FROM AUTHOR]
- Published
- 2008
- Full Text
- View/download PDF
36. Family-based dispatching: anticipating future jobs.
- Author
-
Nomden, G., Van Der Zee, D.-J., and Slomp, J.
- Subjects
GROUP technology ,PRODUCTION management (Manufacturing) ,MACHINE shops ,PRODUCT design ,OCCUPATIONS - Abstract
Group Technology exploits similarities in product and process design to meet the diversity of customer demand in an economic way. In this paper we consider one of the implementations of this concept - family-based dispatching. Intrinsic to family-based dispatching is the grouping of similar types of products for joint processing. In this way the number of set-ups may be reduced. Consequently, lead-time performance of the shop can be improved. We extend existing rules for family-based dispatching by including data on upcoming job arrivals. Typically, this type of data resides in the minds of the operators, or is stored in a shop-floor control system. Its availability allows for (1) better estimates of the composition of a process batch for a family, (2) the consideration of families for which no products are available at the decision moment, and (3) the possibility to start set-ups in anticipation of future job arrivals. The potential of including forecast data in decision-making is demonstrated by an extensive simulation study of a single-machine shop. Results indicate the possibility of significant improvements of flow time performance. [ABSTRACT FROM AUTHOR]
- Published
- 2008
- Full Text
- View/download PDF
37. Performance comparison of virtual cellular manufacturing with functional and cellular layouts in DRC settings.
- Author
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Suresh *, N. C. and Slomp, J.
- Subjects
MANUFACTURING processes ,VIRTUAL reality ,MANUFACTURING cells ,LABOR ,WORKSHOPS (Facilities) ,PRODUCTION management (Manufacturing) ,OCCUPATIONAL training - Abstract
This study investigates the performance of virtual cellular manufacturing (VCM) systems, comparing them with functional layouts (FL) and traditional, physical cellular layout (CL), in a dual-resource-constrained (DRC) system context, VCM systems employ logical cells, retaining the process layouts of job shops. Part family-based scheduling rules are applied to exploit the benefits of group technology while retaining the flexibility and functional synergies of the job shop. Past studies of VCM have been based entirely on single-resource-constrained (SRC) systems, i.e. as purely machine-limited systems, assuming that resources such as labour and tooling do not restrict the output. However, given the fact that labour forms a second major constraining resource, and many of the advantages associated with cellular manufacturing are derived from labour flexibility, it becomes necessary to extend the research to DRC systems. In this study, we assume several levels of labour flexibility in all three systems, in addition to other relevant factors such as lot size, set-up reduction, and labour assignment rules. It is shown that VCM can outperform efficiently operated FL and CL in certain parameter ranges, as preliminary research has shown so far. However, it is shown that CL tends to outperform both VCM and FL in the parameter ranges customarily advocated for CL, namely, low lot sizes, adequate levels of set-up reduction, cross training of workers, and worker mobility within cells. [ABSTRACT FROM AUTHOR]
- Published
- 2005
- Full Text
- View/download PDF
38. On the who-rule in Dual Resource Constrained (DRC) manufacturing systems.
- Author
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Bokhorst *, J. A. C., Slomp, J., and Gaalman, G. J. C.
- Subjects
PRODUCTION management (Manufacturing) ,INDUSTRIAL engineering ,MANUFACTURED products ,RESOURCE allocation ,INDUSTRIAL management - Abstract
The who-rule is a labour allocation rule used in labour and machine-limited dual resource constrained (DRC) systems. A who-rule selects one worker out of several workers to be transferred to a work centre. By means of a practical instance, the paper shows that the who-rule plays a role in the daily practice of worker assignment. Previous simulation studies, however, either have not mentioned the who-rule or have treated it as a fixed factor. The present study will explore the need of including the who-rule in simulation studies. It will describe in detail at what decision moments the who-rule needs to be applied in simulation. Further, it will explore the flow time effects of applying different who-rules in several DRC systems where labour flexibility is limited and workers differ with respect to task proficiencies, the number of skills they possess and the loads of work centres for which they are responsible. As with other labour allocation rules, the impact of the who-rule depends on the specific DRC shop modelled. The paper will show that the average labour utilization, and the types and extent of worker differences, determine the impact of the who-rule on shop performance. [ABSTRACT FROM AUTHOR]
- Published
- 2004
- Full Text
- View/download PDF
39. A multi-objective procedure for labour assignments and grouping in capacitated cell formation problems.
- Author
-
Suresh, N. C. and Slomp, J.
- Subjects
MANUFACTURING cells ,TEAMS in the workplace ,ARTIFICIAL neural networks ,MATHEMATICAL programming ,DESIGN - Abstract
A hierarchical methodology for the design of manufacturing cells is proposed, which includes labour-grouping considerations in addition to part–machine grouping. It is empirically driven and designed for an interactive decision environment, with an emphasis on fast execution times. The method synthesizes the capabilities of neural network methods for rapid clustering of large part–machine data sets, with multi-objective optimization capabilities of mathematical programming. The procedure includes three phases. In Phase I, part families and associated machine types are identified through neural network methods. Phase II involves a prioritization of part families identified, along with adjustments to certain load-related parameters. Phase III involves interactive goal programming for regrouping machines and labour into cells. In machine grouping, factors such as capacity constraints, cell size restrictions, minimization of load imbalances, minimization of intercell movements of parts, minimization of new machines to be purchased, provision of flexibility, etc. are considered. In labour grouping, the functionally specialized labour pools are partitioned and regrouped into cells. Factors such as minimization of hiring and cross-training costs, ensuring balanced loads for workers, minimization of intercell movements of workers, providing adequate levels of labour flexibility, etc. are considered in a pragmatic manner. [ABSTRACT FROM AUTHOR]
- Published
- 2001
- Full Text
- View/download PDF
40. Immunohistochemical analysis of the plasminogen activation system and the matrix metalloproteinases in normal and atherosclerotic human vessels
- Author
-
Wijnberg, M.J., Slomp, J., and Verheijen, J.H.
- Published
- 1999
- Full Text
- View/download PDF
41. Verbeterborden bekeken : Gebruik van het verbeterbord, theorie en praktijk
- Author
-
Ahaus, C.T.B., Slomp, J., and Roemeling, O.P.
- Abstract
In veel zorgorganisaties die werken met lean methoden treffen we het verbeterbord aan. Verbeterborden inzetten is in de praktijk echter niet zo eenvoudig. De oorzaak hiervan is vaak onduidelijk. Vandaar dat de auteurs het gebruik van het verbeterbord hebben geanalyseerd vanuit de doelen van het verbeterbord. Dit gebeurt aan de hand van drie casussen.
- Published
- 2013
42. Impact of lean interventions on time buffer reduction in a hospital setting.
- Author
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Roemeling, O., Land, M.J., Ahaus, C.T.B. (Kees), Slomp, J. (Jennita), van den Bijllaardt, W., Roemeling, O., Land, M.J., Ahaus, C.T.B. (Kees), Slomp, J. (Jennita), and van den Bijllaardt, W.
- Abstract
This paper focuses on performance changes stemming from a series of lean interventions in a medical laboratory. This research is one of the first to link a series of lean interventions and performance over time. In a mixed-method case study, six years of patient-related throughput data, retrieved from a laboratory computer database, are analysed. Three distinct periods with significant differences in throughput time performance can be distinguished. Semi-structured interviews were held to investigate the lean interventions preceding the performance changes. Given the long-term nature of the study, the event history calendar method was applied to enhance the respondents’ recall and reliability. A single lean intervention, among the hundreds that took place, was supposed to cause the main reduction in throughput times. It concentrate
- Published
- 2017
- Full Text
- View/download PDF
43. Tarieven voor inboeken en uitgifte van transfusie-eenheden en hemovigilantiewerkzaamheden
- Author
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Slomp, J., Soons, J.W.P.H., Henskens, Yvonne, de Rijke, Y.B., Vossen, R.C.R.M., Kortlandt, W., Medische Microbiologie, MUMC+: DA CDL Algemeen (9), and RS: CARIM - R1.04 - Clinical thrombosis and haemostasis
- Published
- 2016
44. The cost of transfusing a unit of red blood cells: a costing model for Canadian hospital use
- Author
-
Lagerquist, O., primary, Poseluzny, D., additional, Werstiuk, G., additional, Slomp, J., additional, Maier, M., additional, Nahirniak, S., additional, and Clarke, G., additional
- Published
- 2017
- Full Text
- View/download PDF
45. Sociotechnical Evaluation of Alternative and Innovative Shop Floor Control Systems
- Author
-
Slomp, J., primary
- Published
- 2017
- Full Text
- View/download PDF
46. Sequence-dependent clustering of parts and machines: a Fuzzy ART neural network approach.
- Author
-
Suresh, N. C., Slomp, J., and Kaparthi, S.
- Subjects
MANUFACTURING cells ,ARTIFICIAL neural networks ,FUZZY algorithms ,PATTERN recognition systems - Abstract
This study addresses the problem of identifying families of parts having a similar sequence of operations. This is a prerequisite for the implementation of cellular manufacturing, group technology, just-in-time manufacturing systems, and for streamlining material flows in general. A pattern recognition approach based on artificial neural networks is proposed, and it is shown that the Fuzzy ART neural network can be effectively utilized for this application. First, a representation scheme for operation sequences is developed, followed by an illustrative example. A more comprehensive experimental verification, based on the mixture-model approach is then performed to evaluate its performance. The experimental factors include size of the part-machine matrix, proportion of voids, proportion of exceptional elements, and vigilance threshold. It is shown that this neural network is effective in identifying good clustering solutions, consistently and with relatively fast execution times. [ABSTRACT FROM AUTHOR]
- Published
- 1999
- Full Text
- View/download PDF
47. Functional flexibility and team performance.
- Author
-
Molleman, E. and Slomp, J.
- Subjects
FLEXTIME ,EMPLOYEES' workload ,ORGANIZATIONAL effectiveness - Abstract
This study deals with workforce flexibility defined in terms of 'multifunctionality' and 'redundancy'. These concepts refer, respectively, to the number of different tasks a worker has mastered and the number of workers that are qualified to do a specific task. A third factor to be considered is worker efficiency. These elements of workforce flexibility support a team of workers in dealing with absenteeism and a fluctuating mix in the demand of human resources. The main focus of this study is on the impact of the distribution of workforce flexibility among workers on team performance. In this study, team performance is measured as the shortage of labour capacity, the minimum time needed to perform all tasks (e.g. the timespan) and the total cumulative production time. Two extreme assignment methods, which include a linear goal-programming formulation that minimizes the shortage, makespan and production time, are used in a full orthogonal factorial experimental design (2.2.5.5). The MANOVA results show that a uniform distribution of multifunctionality results in a shorter makespan and lower total production time. The more absenteeism, the stronger these effects. Absenteeism has a very negative impact on all performance measures, independent of the distribution of flexibility. This study shows that, in cases of absenteeism, the workload of the bottleneck worker will increase relatively more than the workload of the remaining operators. Since the bottleneck worker determines the makespan, there will be greater waiting time for the other team members. This may be contra to intuition which tells us that absenteeism will increase the relative workload (or utilization level) of the remaining workers. With respect to the distribution of redundancy, our study shows that each task should be mastered by at least two workers in order to reduce the negative impact of low to moderate levels of absenteeism. Above this minimal level of task redundancy, labour flexibility... [ABSTRACT FROM AUTHOR]
- Published
- 1999
- Full Text
- View/download PDF
48. The capacitated cell formation problem: a new hierarchical methodology.
- Author
-
Suresh, N. C., Slomp, J., and Kaparthi, S.
- Subjects
HIERARCHIES ,MANUFACTURING cells ,METHODOLOGY ,PATTERN recognition systems ,MANUFACTURING processes ,MATHEMATICAL programming ,MACHINERY ,TECHNOLOGY - Abstract
In this paper, a hierarchical methodology for the design of manufacturing cells is proposed, synthesizing the capabilities of new pattern recognition methods for rapid clustering of large part-machine data sets, with multi-objective optimization capabilities of mathematical programming. The procedure includes three phases. In Phase I, part families and associated machine types are identified through neural network methods for pattern recognition. Phase II is a celt formation phase that involves the assignment of part families and individual machines to create independent cells. It takes into account several factors such as capacity constraints, cell size restrictions, minimization of load imbalances and provision of flexibility. Phase III attempts to minimize inter-cell traffic further for families that may still have to be processed in more than one cell. The methodology is illustrated using several examples. [ABSTRACT FROM AUTHOR]
- Published
- 1995
- Full Text
- View/download PDF
49. Quasi on-line scheduling procedures for flexible manufacturing systems.
- Author
-
Slomp, J., Gaalman, G.J.C., and Nawijn, W.M.
- Subjects
PRODUCTION scheduling ,FLEXIBLE manufacturing systems - Abstract
This paper presents three quasi on-line scheduling procedures for FMSs consisting of work stations, transport devices, and operators. In the scheduling, different types of decisions are taken to perform a particular operation, i.e. the selection of (a) a work station, (b) a transport device and (c) an operator. Further, (d) the scheduling sequence of the operations has to be determined. The three developed procedures differ in the way these four decision problems arc solved hierarchically. Several dispatching rules (SPT, SPT.TOT, SPT/TOT and EFTA) are available to solve the last mentioned decision problem. Limited buffer capacities in an FMS may cause deadlock in the procedures as well as in practice. The scheduling procedures involve a buffer handling method to avoid deadlock. A case study is presented to demonstrate the three procedures and to show some of its properties. Based on simulation tests, some conclusions are drawn about the performance of the scheduling procedures and the various dispatching rules. [ABSTRACT FROM AUTHOR]
- Published
- 1988
- Full Text
- View/download PDF
50. Prestatieverbetering over langere tijd: Het effect van lean op doorlooptijden op het LMMI , St. Elisabeth-Tweesteden Ziekenhuis
- Author
-
Roemeling, O.P., Bijllaardt, W. van den, Land, M.J., Ahaus, K., Slomp, J., Voort, M.C. van der, Voort, Marc Rouppe van der, and Benders, Jos
- Published
- 2014
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