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11. The effect of regular fitness training, sex hormones, and turnover of selected bone markers on sclerostin levels in young women.

Author

Plinta, Ryszard, Czajkowska, Mariola, Pisula, Magdalena, Brzęk, Anna, Knapik, Andrzej, Olszanecka-Glinianowicz, Magdalena, and Skrzypulec-Plinta, Violetta

Subjects
SEX hormones, SCLEROSTIN, YOUNG women, BONE remodeling, VITAMIN D, ANAEROBIC capacity, OSTEOBLASTS
Abstract

Introduction: Regular physical activity (PA) is a recognized factor stimulating bone formation. In recent years, osteocytes have been shown to be involved in the metabolism of bone tissue in addition to osteoblasts and osteoclasts. The aim of the study was to analyze the effects of regular fitness training, sex hormones, and selected bone turnover markers on sclerostin levels in young women. Material and methods: The cross-sectional study involved 78 women including 39 who regularly engaged in fitness training (for 1 h three times a week for 3 months) and 39 leading a sedentary lifestyle. Anthropometric measurements and glucose, lipids, insulin, estradiol, testosterone, free testosterone, androstenedione, dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate, intact parathyroid hormone (iPTH), vitamin D, osteocalcin, β isomer of C-terminal telopeptide of type I collagen (β-CTx) and sclerostin levels were measured. Results: Activity of women (study group) who were on a high level of PA ranged between 2262 and 6606 MET/min/week (mean, 3843.16; SD = 1230). All of the control group were on low level of PA (198-1617 MET/min/week; mean, 841.06; SD = 302.01). Significantly higher levels of iPTH and β-CTx were observed in the study than in the control group (p < 0.01). We did not observe differences in vitamin D (p > 0.12), osteocalcin (p > 0.23), or sclerostin levels (p > 0.37) between groups. There were significant negative correlations between log10 sclerostin and log10 DHEA levels (r = -0.24; p < 0.05). A multivariate stepwise backward linear regression model for sclerostin as an independent variable, with the explanatory variables physical activity, estradiol, testosterone, and DHEA levels, did not reveal any effect on changes of sclerostin levels. The model with the explanatory variables vitamin D, iPTH, β-CTx, and osteocalcin also did not show effects on changes of sclerostin levels. Conclusions: Our results show that regular fitness training, sex hormones, vitamin D, iPTH, β-CTx, and osteocalcin did not influence circulating sclerostin levels in young women. [ABSTRACT FROM AUTHOR]

Published
2023
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24. Position statement by Experts of the Polish Menopause and Andropause Society, and the Polish Society of Aesthetic and Reconstructive Gynaecology on the medicinal product Intrarosa

Author

Maciej Wilczak, Małgorzata Bińkowska, Tomasz Paszkowski, Skrzypulec-Plinta Violetta, and Wojciech Zgliczyński

Subjects
Position statement, medicine.medical_specialty, 030219 obstetrics & reproductive medicine, business.industry, Genitourinary system, Endocrinology, Diabetes and Metabolism, lcsh:R, MEDLINE, lcsh:Medicine, Obstetrics and Gynecology, Scientific literature, medicine.disease, Terminology, Menopause, 03 medical and health sciences, 0302 clinical medicine, Family medicine, medicine, Featured Paper, Product (category theory), business, Reproductive health
Abstract

A set of menopause-related symptoms affecting the external genitalia and lower urinary tract is discussed in contemporary scientific literature under the name of urogenital atrophy (UGA) or vulvovaginal atrophy (VVA) [1]. In 2014, a team of experts from two scientific associations – The North American Menopause Society (NAMS) and The International Society for the Study of Women’s Sexual Health (ISSWSH) – proposed a new terminology for postmenopausal atrophic symptoms, replacing the terms VVA and UGA with the term genitourinary syndrome of menopause (GSM) [2]. The change was motivated by the belief that this set of symptoms requires a more holistic therapeutic approach falling outside the scope of interest of gynaecologists and urologists only. The signs and symptoms of GSM are summarised in the Table 1. Table 1 Genitourinary syndrome of menopause (GSM) –symptoms and signs

Published
2020

25. Recommendations of the Group of Experts of the Polish Society of Gynecologists and Obstetricians regarding proceeding with victims of crimes against sexual freedom (01.01.2021)

Author

Drosdzol-Cop, Agnieszka, primary, Skrzypulec-Plinta, Violetta, additional, Guzik-Makaruk, Ewa M., additional, Drozdowska, Urszula, additional, Huzarska, Dorota, additional, Kluz-Kowal, Anna B., additional, Ruminska, Jagna, additional, Ciupa, Michal, additional, Cop, Waldemar, additional, and Czech, Iwona Joanna, additional

Published
2021
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28. Physical activity in students of the Medical University of Silesia in Poland

Author

Dabrowska-Galas, Magdalena, Plinta, Ryszard, Dabrowska, Jolanta, and Skrzypulec-Plinta, Violetta

Subjects
Exercise -- Health aspects -- Research, Health promotion -- Research, Medical students -- Health aspects -- Training -- Research, Physical fitness -- Demographic aspects -- Research, Physical therapists -- Health aspects -- Training -- Research, Health
Abstract

Background. Medical students and other health care professionals have substantial knowledge of the benefits of regular physical activity. Furthermore, as they have an ethical obligation to prescribe suitable exercises, they can influence their patients' attitude toward physical activity and can become role models for their patients. Physical therapists, who are primary care practitioners, have great potential for promoting physical activity; however, their role is still underestimated by patients and health care professionals. Objective. The objectives of this study were to evaluate physical activity level in students of the Medical University of Silesia in Poland and to focus on the role of physical therapist students in promoting physical activity. Design. This was a cross-sectional study. Methods. The final analysis included 300 students from the schools of physical therapy, midwifery, nursing, pharmacy, cosmetology, and medicine at the Medical University of Silesia. The short form of the International Physical Activity Questionnaire (IPAQ) was used to evaluate physical activity level. Results. Physical therapist students demonstrated the highest level of physical activity, with 46% demonstrating a high level of physical activity, 54% a moderate level of physical activity, and none a low level of physical activity. The largest group of students with a low level of physical activity comprised students from the school of medicine (26%). Limitations. The number of respondents was relatively small. The main study limitations included its cross-sectional nature and the possibility of self-report biases. Further research is warranted to expand the study nationally and determine which factors influence physical activity. Conclusions. There was a large group of medical students who, despite being aware of benefits of physical activity, did not meet the recommended level of physical activity. Physical therapist students are well trained and qualified to promote healthy habits and encourage individuals to undertake regular physical activity., Physical inactivity and the associated health problems pose a current and growing threat to public health. (1) The World Health Organization (WHO) reports that approximately 60% of the global population [...]

Published
2013
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40. Recommendations of the Group of Experts of the Polish Society of Gynecologists and Obstetricians in the field of gynecological and obstetric care of young women with physical and intellectual disabilities

Author

Drosdzol-Cop, Agnieszka, primary, Fuchs, Anna, additional, Skrzypulec-Plinta, Violetta, additional, Radomski, Dariusz, additional, Jarzabek-Bielecka, Grazyna, additional, Czech, Iwona, additional, Dulska, Agnieszka, additional, and Szul, Mateusz, additional

Published
2020
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42. Sexual Functioning in Pregnant Women

Author

Fuchs, Anna, primary, Czech, Iwona, additional, Sikora, Jerzy, additional, Fuchs, Piotr, additional, Lorek, Miłosz, additional, Skrzypulec-Plinta, Violetta, additional, and Drosdzol-Cop, Agnieszka, additional

Published
2019
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