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7 results on '"Siverts, La’ Akea"'

1. A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types

Author

Ben-Simon, Yoav, primary, Hooper, Marcus, additional, Narayan, Sujatha, additional, Daigle, Tanya, additional, Dwivedi, Deepanjali, additional, Way, Sharon W, additional, Oster, Aaron, additional, Stafford, David A, additional, Mich, John K, additional, Taormina, Michael J, additional, Martinez, Refugio A, additional, Opitz-Araya, Ximena, additional, Roth, Jada R, additional, Allen, Shona, additional, Ayala, Angela, additional, Bakken, Trygve E, additional, Barcelli, Tyler, additional, Barta, Stuard, additional, Bendrick, Jacqueline, additional, Bertagnolli, Darren, additional, Bowlus, Jessica, additional, Boyer, Gabriella, additional, Brouner, Krissy, additional, Casian, Brittny, additional, Casper, Tamara, additional, Chakka, Anish B, additional, Chakrabarty, Rushil, additional, Chance, Rebecca K, additional, Chavan, Sakshi, additional, Departee, Maxwell, additional, Donadio, Nicholas, additional, Dotson, Nadezhda, additional, Egdorf, Tom, additional, Gabitto, Mariano, additional, Gary, Amanda, additional, Gasperini, Molly, additional, Goldy, Jeff, additional, Gore, Bryan B, additional, Graybuck, Lucas, additional, Greisman, Noah, additional, Haeseleer, Francoise, additional, Halterman, Carliana, additional, Helback, Olivia, additional, Hockmeyer, Dirk, additional, Huang, Cindy, additional, Huff, Sydney, additional, Hunker, Avery, additional, Johansen, Nelson, additional, Juneau, Zoe, additional, Kalmbach, Brian, additional, Khem, Shannon, additional, Kutsal, Rana, additional, Larsen, Rachael, additional, Lee, Changkyu, additional, Lee, Angus Y, additional, Leibly, Madison, additional, Lenz, Garreck H, additional, Liang, Elizabeth, additional, Lusk, Nicholas, additional, Malone, Jocelin, additional, Mollenkopf, Tyler, additional, Morin, Elyse, additional, Newman, Dakota, additional, Ng, Lydia, additional, Ngo, Kiet, additional, Omstead, Victoria, additional, Oyama, Alana, additional, Pham, Trangthanh, additional, Pom, Christina A, additional, Potekhina, Lydia, additional, Ransford, Shea, additional, Rette, Dean, additional, Rimorin, Christine, additional, Rocha, Dana, additional, Ruiz, Augustin, additional, Sanchez, Raymond E.A., additional, Sedeno-Cortes, Adriana, additional, Sevigny, Joshua P, additional, Shapovalova, Nadiya, additional, Shulga, Lyudmila, additional, Sigler, Ana R, additional, Siverts, La Akea, additional, Somasundaram, Saroja, additional, Stewart, Kaiya, additional, Tieu, Michael, additional, Trader, Cameron, additional, van Velthoven, Cindy T.J., additional, Walker, Miranda, additional, Weed, Natalie, additional, Wirthlin, Morgan, additional, Wood, Toren, additional, Wynalda, Brooke, additional, Yao, Zizhen, additional, Zhou, Thomas, additional, Ariza, Jeanelle, additional, Dee, Nick, additional, Reding, Melissa, additional, Ronellenfitch, Kara, additional, Mufti, Shoaib, additional, Sunkin, Susan M, additional, Smith, Kimberly A, additional, Esposito, Luke, additional, Waters, Jack, additional, Thyagarajan, Bargavi, additional, Yao, Shenqin, additional, Lein, Ed, additional, Zeng, Hongkui, additional, Levi, Boaz P, additional, Ngai, John, additional, Ting, Jonathan T, additional, and Tasic, Bosiljka, additional

Published
2024
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2. A Suite of Transgenic Driver and Reporter Mouse Lines with Enhanced Brain-Cell-Type Targeting and Functionality

Author

Daigle, Tanya L., Madisen, Linda, Hage, Travis A., Valley, Matthew T., Knoblich, Ulf, Larsen, Rylan S., Takeno, Marc M., Huang, Lawrence, Gu, Hong, Larsen, Rachael, Mills, Maya, Bosma-Moody, Alice, Siverts, La’ Akea, Walker, Miranda, Graybuck, Lucas T., Yao, Zizhen, Fong, Olivia, Nguyen, Thuc Nghi, Garren, Emma, Lenz, Garreck H., Chavarha, Mariya, Pendergraft, Julie, Harrington, James, Hirokawa, Karla E., Harris, Julie A., Nicovich, Philip R., McGraw, Medea J., Ollerenshaw, Douglas R., Smith, Kimberly A., Baker, Christopher A., Ting, Jonathan T., Sunkin, Susan M., Lecoq, Jérôme, Lin, Michael Z., Boyden, Edward S., Murphy, Gabe J., da Costa, Nuno M., Waters, Jack, Li, Lu, Tasic, Bosiljka, Zeng, Hongkui, Daigle, Tanya L., Madisen, Linda, Hage, Travis A., Valley, Matthew T., Knoblich, Ulf, Larsen, Rylan S., Takeno, Marc M., Huang, Lawrence, Gu, Hong, Larsen, Rachael, Mills, Maya, Bosma-Moody, Alice, Siverts, La’ Akea, Walker, Miranda, Graybuck, Lucas T., Yao, Zizhen, Fong, Olivia, Nguyen, Thuc Nghi, Garren, Emma, Lenz, Garreck H., Chavarha, Mariya, Pendergraft, Julie, Harrington, James, Hirokawa, Karla E., Harris, Julie A., Nicovich, Philip R., McGraw, Medea J., Ollerenshaw, Douglas R., Smith, Kimberly A., Baker, Christopher A., Ting, Jonathan T., Sunkin, Susan M., Lecoq, Jérôme, Lin, Michael Z., Boyden, Edward S., Murphy, Gabe J., da Costa, Nuno M., Waters, Jack, Li, Lu, Tasic, Bosiljka, and Zeng, Hongkui

Abstract

An expanded toolkit of transgenic mouse lines for exploring the organization, function, and development of mammalian neural circuits.

Published
2022

3. Enhancer viruses for combinatorial cell-subclass-specific labeling

Author

Graybuck, Lucas T., primary, Daigle, Tanya L., additional, Sedeño-Cortés, Adriana E., additional, Walker, Miranda, additional, Kalmbach, Brian, additional, Lenz, Garreck H., additional, Morin, Elyse, additional, Nguyen, Thuc Nghi, additional, Garren, Emma, additional, Bendrick, Jacqueline L., additional, Kim, Tae Kyung, additional, Zhou, Thomas, additional, Mortrud, Marty, additional, Yao, Shenqin, additional, Siverts, La’ Akea, additional, Larsen, Rachael, additional, Gore, Bryan B., additional, Szelenyi, Eric R., additional, Trader, Cameron, additional, Balaram, Pooja, additional, van Velthoven, Cindy T.J., additional, Chiang, Megan, additional, Mich, John K., additional, Dee, Nick, additional, Goldy, Jeff, additional, Cetin, Ali H., additional, Smith, Kimberly, additional, Way, Sharon W., additional, Esposito, Luke, additional, Yao, Zizhen, additional, Gradinaru, Viviana, additional, Sunkin, Susan M., additional, Lein, Ed, additional, Levi, Boaz P., additional, Ting, Jonathan T., additional, Zeng, Hongkui, additional, and Tasic, Bosiljka, additional

Published
2021
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5. Enhancer viruses and a transgenic platform for combinatorial cell subclass-specific labeling

Author

Graybuck, Lucas T., primary, Daigle, Tanya L., additional, Sedeño-Cortés, Adriana E., additional, Walker, Miranda, additional, Kalmbach, Brian, additional, Lenz, Garreck H., additional, Nguyen, Thuc Nghi, additional, Garren, Emma, additional, Kim, Tae Kyung, additional, Siverts, La’ Akea, additional, Bendrick, Jacqueline L., additional, Zhou, Thomas, additional, Mortrud, Marty, additional, Yao, Shenqin, additional, Cetin, Ali H., additional, Larsen, Rachael, additional, Esposito, Luke, additional, Gore, Bryan, additional, Szelenyi, Eric, additional, Morin, Elyse, additional, Mich, John K., additional, Dee, Nick, additional, Goldy, Jeff, additional, Smith, Kimberly, additional, Yao, Zizhen, additional, Gradinaru, Viviana, additional, Sunkin, Susan M., additional, Lein, Ed, additional, Levi, Boaz P., additional, Ting, Jonathan T., additional, Zeng, Hongkui, additional, and Tasic, Bosiljka, additional

Published
2019
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6. A Suite of Transgenic Driver and Reporter Mouse Lines with Enhanced Brain-Cell-Type Targeting and Functionality

Author

Daigle, Tanya L., primary, Madisen, Linda, additional, Hage, Travis A., additional, Valley, Matthew T., additional, Knoblich, Ulf, additional, Larsen, Rylan S., additional, Takeno, Marc M., additional, Huang, Lawrence, additional, Gu, Hong, additional, Larsen, Rachael, additional, Mills, Maya, additional, Bosma-Moody, Alice, additional, Siverts, La’ Akea, additional, Walker, Miranda, additional, Graybuck, Lucas T., additional, Yao, Zizhen, additional, Fong, Olivia, additional, Nguyen, Thuc Nghi, additional, Garren, Emma, additional, Lenz, Garreck H., additional, Chavarha, Mariya, additional, Pendergraft, Julie, additional, Harrington, James, additional, Hirokawa, Karla E., additional, Harris, Julie A., additional, Nicovich, Philip R., additional, McGraw, Medea J., additional, Ollerenshaw, Douglas R., additional, Smith, Kimberly A., additional, Baker, Christopher A., additional, Ting, Jonathan T., additional, Sunkin, Susan M., additional, Lecoq, Jérôme, additional, Lin, Michael Z., additional, Boyden, Edward S., additional, Murphy, Gabe J., additional, da Costa, Nuno M., additional, Waters, Jack, additional, Li, Lu, additional, Tasic, Bosiljka, additional, and Zeng, Hongkui, additional

Published
2018
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7. A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types.

Author

Ben-Simon Y, Hooper M, Narayan S, Daigle T, Dwivedi D, Way SW, Oster A, Stafford DA, Mich JK, Taormina MJ, Martinez RA, Opitz-Araya X, Roth JR, Allen S, Ayala A, Bakken TE, Barcelli T, Barta S, Bendrick J, Bertagnolli D, Bowlus J, Boyer G, Brouner K, Casian B, Casper T, Chakka AB, Chakrabarty R, Chance RK, Chavan S, Departee M, Donadio N, Dotson N, Egdorf T, Gabitto M, Garcia J, Gary A, Gasperini M, Goldy J, Gore BB, Graybuck L, Greisman N, Haeseleer F, Halterman C, Helback O, Hockemeyer D, Huang C, Huff S, Hunker A, Johansen N, Juneau Z, Kalmbach B, Khem S, Kussick E, Kutsal R, Larsen R, Lee C, Lee AY, Leibly M, Lenz GH, Liang E, Lusk N, Malone J, Mollenkopf T, Morin E, Newman D, Ng L, Ngo K, Omstead V, Oyama A, Pham T, Pom CA, Potekhina L, Ransford S, Rette D, Rimorin C, Rocha D, Ruiz A, Sanchez REA, Sedeno-Cortes A, Sevigny JP, Shapovalova N, Shulga L, Sigler AR, Siverts LA, Somasundaram S, Stewart K, Szelenyi E, Tieu M, Trader C, van Velthoven CTJ, Walker M, Weed N, Wirthlin M, Wood T, Wynalda B, Yao Z, Zhou T, Ariza J, Dee N, Reding M, Ronellenfitch K, Mufti S, Sunkin SM, Smith KA, Esposito L, Waters J, Thyagarajan B, Yao S, Lein ES, Zeng H, Levi BP, Ngai J, Ting J, and Tasic B

Abstract

The mammalian cortex is comprised of cells classified into types according to shared properties. Defining the contribution of each cell type to the processes guided by the cortex is essential for understanding its function in health and disease. We used transcriptomic and epigenomic cortical cell type taxonomies from mouse and human to define marker genes and putative enhancers and created a large toolkit of transgenic lines and enhancer AAVs for selective targeting of cortical cell populations. We report evaluation of fifteen new transgenic driver lines, two new reporter lines, and >800 different enhancer AAVs covering most subclasses of cortical cells. The tools reported here as well as the scaled process of tool creation and modification enable diverse experimental strategies towards understanding mammalian cortex and brain function.

Published
2024
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