Search

Your search keyword '"Sissi Xiang"' showing total 3 results
Start Over Author "Sissi Xiang"
3 results on '"Sissi Xiang"'

1. Comparison of PED and FRED flow diverters for posterior circulation aneurysms: a propensity score matched cohort study

Author

Erasmia Müller-Thies-Broussalis, Ajith J. Thomas, Michael Sonnberger, Peter Kan, Alejandro Enriquez-Marulanda, Christian Ulfert, Waleed Brinjikji, Adnan H. Siddiqui, Ramesh Grandhi, Robert A. Hirschl, Civan Islak, Sissi Xiang, Mark R. Harrigan, Muhammad Waqas, Adam A Dmytriw, Timo Krings, Vincent M. Tutino, Vitor Mendes Pereira, Lorenzo Rinaldo, Arsalaan Salehani, Markus Holtmannspötter, Jan-Karl Burkhardt, Christopher J Stapleton, Tao Hong, Markus A Möhlenbruch, Julian Spears, Leonardo Renieri, Matthew J. Koch, Elad I. Levy, Naci Kocer, Andreas Simgen, Oded Goren, Christoph J. Griessenauer, Clemens M. Schirmer, J. H. Buhk, Monika Killer-Oberpfalzer, Carmen Parra-Fariñas, Wolfgang Reith, Aman B. Patel, Paul M. Foreman, Nicola Limbucci, Mandeep S. Ghuman, Giuseppe Lanzino, Shamsher S. Dalal, Mohammad Ghorbani, Ivan Radovanovic, Charles C. Matouk, Christopher S. Ogilvy, Tobias Engelhorn, Thomas Finkenzeller, Thomas R. Marotta, Philipp Taussky, Karen Chen, Hendrik Janssen, Victor X. D. Yang, Marshall C. Cress, Hongqi Zhang, and Mohammad Ali Aziz-Sultan

Subjects
Adult, Male, medicine.medical_specialty, Ruptured aneurysms, medicine.medical_treatment, Self Expandable Metallic Stents, Aneurysm, Ruptured, 030218 nuclear medicine & medical imaging, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, Matched cohort, Aneurysm, Occlusion, Humans, Medicine, Embolization, Propensity Score, Aged, Retrospective Studies, Flow diverter, business.industry, Intracranial Aneurysm, General Medicine, Middle Aged, Neurovascular bundle, medicine.disease, Embolization, Therapeutic, Blood Vessel Prosthesis, Surgery, Treatment Outcome, Propensity score matching, Female, Neurology (clinical), business, 030217 neurology & neurosurgery, Follow-Up Studies
Abstract

BackgroundFlow diversion is a common endovascular treatment for cerebral aneurysms, but studies comparing different types of flow diverters are scarce.ObjectiveTo perform a propensity score matched cohort study comparing the Pipeline Embolization Device (PED) and Flow Redirection Intraluminal Device (FRED) for posterior circulation aneurysms.MethodsConsecutive aneurysms of the posterior circulation treated at 25 neurovascular centers with either PED or FRED were collected. Propensity score matching was used to control for age, duration of follow-up imaging, adjunctive coiling, and aneurysm location, size, and morphology; previously ruptured aneurysms were excluded. The two devices were compared for the following outcomes: procedural complications, aneurysm occlusion, and functional outcome.ResultsA total of 375 aneurysms of the posterior circulation were treated in 369 patients. The PED was used in 285 (77.2%) and FRED in 84 (22.8%) procedures. Aneurysms treated with the PED were more commonly fusiform and larger than those treated with FRED. To account for these important differences, propensity score matching was performed resulting in 33 PED and FRED unruptured aneurysm pairs. No differences were found in occlusion status and neurologic thromboembolic or hemorrhagic complications between the two devices. The proportion of patients with favorable functional outcome was higher with FRED (100% vs 87.9%, p=0.04).ConclusionComparative analysis of PED and FRED for the treatment of unruptured posterior circulation aneurysms did not identify significant differences in aneurysm occlusion or neurologic complications. Variations in functional outcomes warrant additional investigations.

Published
2020

2. Experience With the Pipeline Embolization Device for Posterior Circulations Aneurysms: A Multicenter Cohort Study

Author

Peter Kan, Mohammad Ali Aziz-Sultan, Shamsher S. Dalal, Ramesh Grandhi, Karen Chen, Jan-Karl Burkhardt, Victor X. D. Yang, Robert A. Hirschl, Arundhati Biswas, Adam A Dmytriw, Christopher J Stapleton, Lorenzo Rinaldo, Erasmia Müller-Thies-Broussalis, Marshall C. Cress, Aman B. Patel, Hongqi Zhang, Tao Hong, Alejandro Enriquez-Marulanda, Mandeep S. Ghuman, Paul M. Foreman, Giuseppe Lanzino, Waleed Brinjikji, Sissi Xiang, Philipp Taussky, Oded Goren, Christoph J. Griessenauer, Timo Krings, Matthew J. Koch, Clemens M. Schirmer, Monika Killer-Oberpfalzer, and Mohammad Ghorbani

Subjects
medicine.medical_specialty, Subarachnoid hemorrhage, medicine.medical_treatment, Cohort Studies, Aneurysm, Occlusion, Medicine, Humans, cardiovascular diseases, Embolization, Stroke, Retrospective Studies, business.industry, Endovascular Procedures, Intracranial Aneurysm, Neurovascular bundle, medicine.disease, Embolization, Therapeutic, Surgery, Treatment Outcome, cardiovascular system, Neurology (clinical), Presentation (obstetrics), business, Cohort study, Follow-Up Studies
Abstract

BACKGROUND: The Pipeline Embolization Device (PED; Medtronic) has been used off-label for the treatment of challenging posterior circulation aneurysms. Data on this modality are primarily limited to small retrospective single-center series. OBJECTIVE: To assess safety and efficacy of this treatment by establishing an international, multicenter collaboration. METHODS: Consecutive posterior circulation aneurysms treated with the PED from 2012 to 2019 across 11 neurovascular centers were retrospectively reviewed. Baseline demographics, aneurysm and treatment characteristics, complications, occlusion status, and functional outcome were assessed. RESULTS: There were 149 posterior circulation aneurysms treated with PED in 146 patients. A total of 24 (16.4) patients presented with subarachnoid hemorrhage. Most aneurysms were dissecting/blister (36.2) in morphology, followed by saccular (35.6) and fusiform (28.2). The most common locations were the vertebral (51.7) and basilar arteries (22.8). Complete or near-complete occlusion (>90) was achieved in 90.9 of aneurysms at a median follow-up of 12 mo. Dissecting/blister aneurysms were most likely to occlude (P =.06). Symptomatic neurologic complications occurred in 9.4 of aneurysms, associated with larger size, ruptured presentation, presentations with brain stem compression, cranial nerve palsy, or stroke. Favorable functional outcome (modified Rankin Score 0-2) was achieved in 86.2 of patients. There were 6 fatalities of which 4 occurred in aneurysmal subarachnoid hemorrhage patients. CONCLUSION: This multicenter study shows that PED for the treatment of posterior circulation is preferentially used for the treatment of fusiform and dissecting/blister aneurysm morphologies. Despite the challenges presented by these less-common morphologies, flow diversion may be performed with a neurologic complication rate of about 10 and favorable long-term aneurysm occlusion rates. © 2020 by the Congress of Neurological Surgeons

Published
2019

3. Comparison of PED and FRED flow diverters for posterior circulation aneurysms: a propensity score matched cohort study.

Author

Griessenauer, Christoph J., Marulanda, Alejandro Enriquez, Sissi Xiang, Tao Hong, Hongqi Zhang, Taussky, Philipp, Grandhi, Ramesh, Waqas, Muhammad, Tutino, Vincent M., Siddiqui, Adnan H., Levy, Elad I., Ogilvy, Christopher S., Thomas, Ajith J., Ulfert, Christian, Möhlenbruch, Markus A., Renieri, Leonardo, Limbucci, Nicola, Fariñas, Carmen Parra, Burkhardt, Jan- Karl, and Kan, Peter

Subjects
ANEURYSM surgery, CEREBRAL circulation, COMPARATIVE studies, LONGITUDINAL method, THERAPEUTIC embolization, MEDICAL equipment reliability, HEART assist devices, DESCRIPTIVE statistics
Abstract

background Flow diversion is a common endovascular treatment for cerebral aneurysms, but studies comparing different types of flow diverters are scarce. Objective To perform a propensity score matched cohort study comparing the Pipeline Embolization Device (PED) and Flow Redirection Intraluminal Device (FRED) for posterior circulation aneurysms. Methods Consecutive aneurysms of the posterior circulation treated at 25 neurovascular centers with either PED or FRED were collected. Propensity score matching was used to control for age, duration of followup imaging, adjunctive coiling, and aneurysm location, size, and morphology; previously ruptured aneurysms were excluded. The two devices were compared for the following outcomes: procedural complications, aneurysm occlusion, and functional outcome. results A total of 375 aneurysms of the posterior circulation were treated in 369 patients. The PED was used in 285 (77.2%) and FRED in 84 (22.8%) procedures. Aneurysms treated with the PED were more commonly fusiform and larger than those treated with FRED. To account for these important differences, propensity score matching was performed resulting in 33 PED and FRED unruptured aneurysm pairs. No differences were found in occlusion status and neurologic thromboembolic or hemorrhagic complications between the two devices. The proportion of patients with favorable functional outcome was higher with FRED (100% vs 87.9%, p=0.04). Conclusion Comparative analysis of PED and FRED for the treatment of unruptured posterior circulation aneurysms did not identify significant differences in aneurysm occlusion or neurologic complications. Variations in functional outcomes warrant additional investigations. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results