1. Frameless Stereotactic Radiosurgery for Treatment of Multiple Sclerosis-Related Trigeminal Neuralgia
- Author
-
A. Brogna, Antonio Pontoriero, Francesco Tomasello, Felice Esposito, Sergio Vinci, Giuseppe Iatì, Francesco Saverio De Ponte, Enrico Nastro Siniscalchi, Salvatore Crimi, Stefano Pergolizzi, Antonino Germanò, Alfredo Conti, Conti Alfredo, Pontoriero A., Iati G., Esposito F., Siniscalchi E.N., Crimi S., Vinci S., Brogna A., De Ponte F., Germano A., Pergolizzi S., and Tomasello F.
- Subjects
Male ,Multiple Sclerosis ,medicine.medical_treatment ,CyberKnife ,Radiosurgery ,Follow-Up Studie ,Rhizotomy ,03 medical and health sciences ,0302 clinical medicine ,Trigeminal neuralgia ,Cyberknife ,Multiple Sclerosi ,medicine ,Humans ,Trigeminal Nerve ,Stereotactic radiosurgery ,Facial numbne ,medicine.diagnostic_test ,business.industry ,Multiple sclerosis ,Magnetic resonance imaging ,Pain scale ,Middle Aged ,Trigeminal Neuralgia ,facial numbness ,medicine.disease ,Magnetic Resonance Imaging ,030220 oncology & carcinogenesis ,Frameless radiosurgery ,Cyberknife, facial numbness, frameless radiosurgery, multiple sclerosis, stereotactic radiosurgery, trigeminal neuralgia ,Surgery ,Female ,Neurology (clinical) ,CyberKnife Radiosurgery ,business ,Nuclear medicine ,Tomography, X-Ray Computed ,030217 neurology & neurosurgery ,Human ,Follow-Up Studies ,Radiotherapy, Image-Guided - Abstract
Background Trigeminal neuralgia (TN) affects 7% of patients with multiple sclerosis (MS). In such patients, TN is difficult to manage either pharmacologically and surgically. Radiosurgical rhizotomy is an effective treatment option. The nonisocentric geometry of radiation beams of CyberKnife introduces new concepts in the treatment of TN. Its efficacy for MS-related TN has not yet been demonstrated. Methods Twenty-seven patients with refractory TN and MS were treated. A nonisocentric beams distribution was chosen; the maximal target dose was 72.5 Gy. The maximal dose to the brainstem was
- Published
- 2017