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2. Discovery of (2R,4R)‑4-((S)‑2-Amino-3-methylbutanamido)-2-(4-boronobutyl)pyrrolidine-2-carboxylic Acid (AZD0011), an Actively Transported Prodrug of a Potent Arginase Inhibitor to Treat Cancer.

Author

Mlynarski, Scott N., Aquila, Brian M., Cantin, Susan, Cook, Steve, Doshi, Aatman, Finlay, M. Raymond V., Gangl, Eric T., Grebe, Tyler, Gu, Chungang, Kawatkar, Sameer P., Petersen, Jens, Pop-Damkov, Petar, Schuller, Alwin G., Shao, Wenlin, Shields, Jason D., Simpson, Iain, Tavakoli, Siavash, Tentarelli, Sharon, Throner, Scott, and Wang, Haixia

Published
2024
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5. 2019 ESC/EAS guidelines for the management of dyslipidaemias: Lipid modification to reduce cardiovascular risk

Author

Mach, François, Baigent, Colin, Catapano, Alberico L., Koskinas, Konstantinos C., Casula, Manuela, Badimon, Lina, Chapman, M. John, De Backer, Guy G., Delgado, Victoria, Ference, Brian A., Graham, Ian M., Halliday, Alison, Landmesser, Ulf, Mihaylova, Borislava, Pedersen, Terje R., Riccardi, Gabriele, Richter, Dimitrios J., Sabatine, Marc S., Taskinen, Marja-Riitta, Tokgozoglu, Lale, Wiklund, Olov, Windecker, Stephan, Aboyans, Victor, Collet, Jean-Philippe, Dean, Veronica, Fitzsimons, Donna, Gale, Chris P., Grobbee, Diederick, Halvorsen, Sigrun, Hindricks, Gerhard, Iung, Bernard, Jüni, Peter, Katus, Hugo A., Leclercq, Christophe, Lettino, Maddalena, Lewis, Basil S., Merkely, Bela, Mueller, Christian, Petersen, Steffen, Petronio, Anna Sonia, Roffi, Marco, Shlyakhto, Evgeny, Simpson, Iain A., Sousa-Uva, Miguel, Touyz, Rhian M., Nibouche, Djamaleddine, Zelveian, Parounak H., Siostrzonek, Peter, Najafov, Ruslan, van de Borne, Philippe, Pojskic, Belma, Postadzhiyan, Arman, Kypris, Lambros, Špinar, Jindřich, Larsen, Mogens Lytken, Eldin, Hesham Salah, Viigimaa, Margus, Strandberg, Timo E., Ferrières, Jean, Agladze, Rusudan, Laufs, Ulrich, Rallidis, Loukianos, Bajnok, László, Gudjónsson, Thorbjörn, Maher, Vincent, Henkin, Yaakov, Gulizia, Michele Massimo, Mussagaliyeva, Aisulu, Bajraktari, Gani, Kerimkulova, Alina, Latkovskis, Gustavs, Hamoui, Omar, Slapikas, Rimvydas, Visser, Laurent, Dingli, Philip, Ivanov, Victoria, Boskovic, Aneta, Nazzi, Mbarek, Visseren, Frank, Mitevska, Irena, Retterstøl, Kjetil, Jankowski, Piotr, Fontes-Carvalho, Ricardo, Gaita, Dan, Ezhov, Marat, Foscoli, Marina, Giga, Vojislav, Pella, Daniel, Fras, Zlatko, Perez de Isla, Leopoldo, Hagström, Emil, Lehmann, Roger, Abid, Leila, Ozdogan, Oner, Mitchenko, Olena, and Patel, Riyaz S.

Published
2019
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7. Editor's Choice – 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS)

Author

Aboyans, Victor, Ricco, Jean-Baptiste, Bartelink, Marie-Louise E.L., Björck, Martin, Brodmann, Marianne, Cohnert, Tina, Collet, Jean-Philippe, Czerny, Martin, De Carlo, Marco, Debus, Sebastian, Espinola-Klein, Christine, Kahan, Thomas, Kownator, Serge, Mazzolai, Lucia, Naylor, A. Ross, Roffi, Marco, Röther, Joachim, Sprynger, Muriel, Tendera, Michal, Tepe, Gunnar, Venermo, Maarit, Vlachopoulos, Charalambos, Desormais, Ileana, Document Reviewers, Widimsky, Petr, Kolh, Philippe, Agewall, Stefan, Bueno, Héctor, Coca, Antonio, De Borst, Gert J., Delgado, Victoria, Dick, Florian, Erol, Cetin, Ferrini, Marc, Kakkos, Stavros, Katus, Hugo A., Knuuti, Juhani, Lindholt, Jes, Mattle, Heinrich, Pieniazek, Piotr, Piepoli, Massimo Francesco, Scheinert, Dierk, Sievert, Horst, Simpson, Iain, Sulzenko, Jakub, Tamargo, Juan, Tokgozoglu, Lale, Torbicki, Adam, Tsakountakis, Nikolaos, Tuñón, José, Vega de Ceniga, Melina, Windecker, Stephan, and Zamorano, Jose Luis

Published
2018
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11. Guía ESC 2020 para el tratamiento de las cardiopatías congénitas del adulto

Author

Baumgartner, Helmut, De Backer, Julie, Babu-Narayan, Sonya V., Budts, Werner, Chessa, Massimo, Diller, Gerhard-Paul, Iung, Bernard, Kluin, Jolanda, Lang, Irene M., Meijboom, Folkert, Moons, Philip, Mulder, Barbara J.M., Oechslin, Erwin, Roos-Hesselink, Jolien W., Schwerzmann, Markus, Sondergaard, Lars, Zeppenfeld, Katja, Ernst, Sabine, Ladouceur, Magalie, Aboyans, Victor, Alexander, David, Christodorescu, Ruxandra, Corrado, Domenico, D’Alto, Michele, de Groot, Natasja, Delgado, Victoria, Di Salvo, Giovanni, Dos Subira, Laura, Eicken, Andreas, Fitzsimons, Donna, Frogoudaki, Alexandra A., Gatzoulis, Michael, Heymans, Stephane, Hörer, Jürgen, Houyel, Lucile, Jondeau, Guillaume, Katus, Hugo A., Landmesser, Ulf, Lewis, Basil S., Lyon, Alexander, Mueller, Christian E., Mylotte, Darren, Petersen, Steffen E., Petronio, Anna Sonia, Roffi, Marco, Rosenhek, Raphael, Shlyakhto, Evgeny, Simpson, Iain A., Sousa-Uva, Miguel, Torp-Pedersen, Christian Tobias, Touyz, Rhian M., and Van De Bruaene, Alexander

Published
2021
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12. Cardiovascular symptoms

Author

Japp, Alan G., primary, Simpson, Iain, additional, Pettit, Stephen, additional, Yue, Arthur, additional, and Zaman, Junaid, additional

Published
2018
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13. Supplementary Figure 1 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners

Author

Doshi, Aatman S., primary, Cantin, Susan, primary, Hernandez, Marylens, primary, Srinivasan, Srimathi, primary, Tentarelli, Sharon, primary, Griffin, Matthew, primary, Wang, Yanjun, primary, Pop-Damkov, Petar, primary, Prickett, Laura B., primary, Kankkonen, Cecilia, primary, Shen, Minhui, primary, Martin, Maryann San, primary, Wu, Song, primary, Castaldi, M. Paola, primary, Ghadially, Hormas, primary, Varnes, Jeffrey, primary, Gales, Sonya, primary, Henry, David, primary, Hoover, Clare, primary, Mele, Deanna A., primary, Simpson, Iain, primary, Gangl, Eric T., primary, Mlynarski, Scott N., primary, Finlay, M. Raymond V., primary, Drew, Lisa, primary, Fawell, Stephen E., primary, Shao, Wenlin, primary, and Schuller, Alwin G., primary

Published
2023
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14. Supplementary Table 1 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners

Author

Doshi, Aatman S., primary, Cantin, Susan, primary, Hernandez, Marylens, primary, Srinivasan, Srimathi, primary, Tentarelli, Sharon, primary, Griffin, Matthew, primary, Wang, Yanjun, primary, Pop-Damkov, Petar, primary, Prickett, Laura B., primary, Kankkonen, Cecilia, primary, Shen, Minhui, primary, Martin, Maryann San, primary, Wu, Song, primary, Castaldi, M. Paola, primary, Ghadially, Hormas, primary, Varnes, Jeffrey, primary, Gales, Sonya, primary, Henry, David, primary, Hoover, Clare, primary, Mele, Deanna A., primary, Simpson, Iain, primary, Gangl, Eric T., primary, Mlynarski, Scott N., primary, Finlay, M. Raymond V., primary, Drew, Lisa, primary, Fawell, Stephen E., primary, Shao, Wenlin, primary, and Schuller, Alwin G., primary

Published
2023
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15. Supplementary Figure 3 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners

Author

Doshi, Aatman S., primary, Cantin, Susan, primary, Hernandez, Marylens, primary, Srinivasan, Srimathi, primary, Tentarelli, Sharon, primary, Griffin, Matthew, primary, Wang, Yanjun, primary, Pop-Damkov, Petar, primary, Prickett, Laura B., primary, Kankkonen, Cecilia, primary, Shen, Minhui, primary, Martin, Maryann San, primary, Wu, Song, primary, Castaldi, M. Paola, primary, Ghadially, Hormas, primary, Varnes, Jeffrey, primary, Gales, Sonya, primary, Henry, David, primary, Hoover, Clare, primary, Mele, Deanna A., primary, Simpson, Iain, primary, Gangl, Eric T., primary, Mlynarski, Scott N., primary, Finlay, M. Raymond V., primary, Drew, Lisa, primary, Fawell, Stephen E., primary, Shao, Wenlin, primary, and Schuller, Alwin G., primary

Published
2023
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16. Supplementary Figure 4 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners

Author

Doshi, Aatman S., primary, Cantin, Susan, primary, Hernandez, Marylens, primary, Srinivasan, Srimathi, primary, Tentarelli, Sharon, primary, Griffin, Matthew, primary, Wang, Yanjun, primary, Pop-Damkov, Petar, primary, Prickett, Laura B., primary, Kankkonen, Cecilia, primary, Shen, Minhui, primary, Martin, Maryann San, primary, Wu, Song, primary, Castaldi, M. Paola, primary, Ghadially, Hormas, primary, Varnes, Jeffrey, primary, Gales, Sonya, primary, Henry, David, primary, Hoover, Clare, primary, Mele, Deanna A., primary, Simpson, Iain, primary, Gangl, Eric T., primary, Mlynarski, Scott N., primary, Finlay, M. Raymond V., primary, Drew, Lisa, primary, Fawell, Stephen E., primary, Shao, Wenlin, primary, and Schuller, Alwin G., primary

Published
2023
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17. Supplementary Figure 5 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners

Author

Doshi, Aatman S., primary, Cantin, Susan, primary, Hernandez, Marylens, primary, Srinivasan, Srimathi, primary, Tentarelli, Sharon, primary, Griffin, Matthew, primary, Wang, Yanjun, primary, Pop-Damkov, Petar, primary, Prickett, Laura B., primary, Kankkonen, Cecilia, primary, Shen, Minhui, primary, Martin, Maryann San, primary, Wu, Song, primary, Castaldi, M. Paola, primary, Ghadially, Hormas, primary, Varnes, Jeffrey, primary, Gales, Sonya, primary, Henry, David, primary, Hoover, Clare, primary, Mele, Deanna A., primary, Simpson, Iain, primary, Gangl, Eric T., primary, Mlynarski, Scott N., primary, Finlay, M. Raymond V., primary, Drew, Lisa, primary, Fawell, Stephen E., primary, Shao, Wenlin, primary, and Schuller, Alwin G., primary

Published
2023
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18. Supplementary Figure 2 from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners

Author

Doshi, Aatman S., primary, Cantin, Susan, primary, Hernandez, Marylens, primary, Srinivasan, Srimathi, primary, Tentarelli, Sharon, primary, Griffin, Matthew, primary, Wang, Yanjun, primary, Pop-Damkov, Petar, primary, Prickett, Laura B., primary, Kankkonen, Cecilia, primary, Shen, Minhui, primary, Martin, Maryann San, primary, Wu, Song, primary, Castaldi, M. Paola, primary, Ghadially, Hormas, primary, Varnes, Jeffrey, primary, Gales, Sonya, primary, Henry, David, primary, Hoover, Clare, primary, Mele, Deanna A., primary, Simpson, Iain, primary, Gangl, Eric T., primary, Mlynarski, Scott N., primary, Finlay, M. Raymond V., primary, Drew, Lisa, primary, Fawell, Stephen E., primary, Shao, Wenlin, primary, and Schuller, Alwin G., primary

Published
2023
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19. Data from Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners

Author

Doshi, Aatman S., primary, Cantin, Susan, primary, Hernandez, Marylens, primary, Srinivasan, Srimathi, primary, Tentarelli, Sharon, primary, Griffin, Matthew, primary, Wang, Yanjun, primary, Pop-Damkov, Petar, primary, Prickett, Laura B., primary, Kankkonen, Cecilia, primary, Shen, Minhui, primary, Martin, Maryann San, primary, Wu, Song, primary, Castaldi, M. Paola, primary, Ghadially, Hormas, primary, Varnes, Jeffrey, primary, Gales, Sonya, primary, Henry, David, primary, Hoover, Clare, primary, Mele, Deanna A., primary, Simpson, Iain, primary, Gangl, Eric T., primary, Mlynarski, Scott N., primary, Finlay, M. Raymond V., primary, Drew, Lisa, primary, Fawell, Stephen E., primary, Shao, Wenlin, primary, and Schuller, Alwin G., primary

Published
2023
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20. Novel Arginase Inhibitor, AZD0011, Demonstrates Immune Cell Stimulation and Antitumor Efficacy with Diverse Combination Partners

Author

Doshi, Aatman S., primary, Cantin, Susan, additional, Hernandez, Marylens, additional, Srinivasan, Srimathi, additional, Tentarelli, Sharon, additional, Griffin, Matthew, additional, Wang, Yanjun, additional, Pop-Damkov, Petar, additional, Prickett, Laura B., additional, Kankkonen, Cecilia, additional, Shen, Minhui, additional, Martin, Maryann San, additional, Wu, Song, additional, Castaldi, M. Paola, additional, Ghadially, Hormas, additional, Varnes, Jeffrey, additional, Gales, Sonya, additional, Henry, David, additional, Hoover, Clare, additional, Mele, Deanna A., additional, Simpson, Iain, additional, Gangl, Eric T., additional, Mlynarski, Scott N., additional, Finlay, M. Raymond V., additional, Drew, Lisa, additional, Fawell, Stephen E., additional, Shao, Wenlin, additional, and Schuller, Alwin G., additional

Published
2023
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21. Supplementary Figure 2 from AZD0364 Is a Potent and Selective ERK1/2 Inhibitor That Enhances Antitumor Activity in KRAS-Mutant Tumor Models when Combined with the MEK Inhibitor, Selumetinib

Author

Flemington, Vikki, primary, Davies, Emma J., primary, Robinson, David, primary, Sandin, Linda C., primary, Delpuech, Oona, primary, Zhang, Pei, primary, Hanson, Lyndsey, primary, Farrington, Paul, primary, Bell, Sigourney, primary, Falenta, Katarzyna, primary, Gibbons, Francis D., primary, Lindsay, Nicola, primary, Smith, Aaron, primary, Wilson, Joanne, primary, Roberts, Karen, primary, Tonge, Michael, primary, Hopcroft, Philip, primary, Willis, Sophie E., primary, Roudier, Martine P., primary, Rooney, Claire, primary, Coker, Elizabeth A., primary, Jaaks, Patricia, primary, Garnett, Mathew J., primary, Fawell, Stephen E., primary, Jones, Clifford D., primary, Ward, Richard A., primary, Simpson, Iain, primary, Cosulich, Sabina C., primary, Pease, J. Elizabeth, primary, and Smith, Paul D., primary

Published
2023
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22. Supplementary Figure 1 from AZD0364 Is a Potent and Selective ERK1/2 Inhibitor That Enhances Antitumor Activity in KRAS-Mutant Tumor Models when Combined with the MEK Inhibitor, Selumetinib

Author

Flemington, Vikki, primary, Davies, Emma J., primary, Robinson, David, primary, Sandin, Linda C., primary, Delpuech, Oona, primary, Zhang, Pei, primary, Hanson, Lyndsey, primary, Farrington, Paul, primary, Bell, Sigourney, primary, Falenta, Katarzyna, primary, Gibbons, Francis D., primary, Lindsay, Nicola, primary, Smith, Aaron, primary, Wilson, Joanne, primary, Roberts, Karen, primary, Tonge, Michael, primary, Hopcroft, Philip, primary, Willis, Sophie E., primary, Roudier, Martine P., primary, Rooney, Claire, primary, Coker, Elizabeth A., primary, Jaaks, Patricia, primary, Garnett, Mathew J., primary, Fawell, Stephen E., primary, Jones, Clifford D., primary, Ward, Richard A., primary, Simpson, Iain, primary, Cosulich, Sabina C., primary, Pease, J. Elizabeth, primary, and Smith, Paul D., primary

Published
2023
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23. Supplementary Table 2 from AZD0364 Is a Potent and Selective ERK1/2 Inhibitor That Enhances Antitumor Activity in KRAS-Mutant Tumor Models when Combined with the MEK Inhibitor, Selumetinib

Author

Flemington, Vikki, primary, Davies, Emma J., primary, Robinson, David, primary, Sandin, Linda C., primary, Delpuech, Oona, primary, Zhang, Pei, primary, Hanson, Lyndsey, primary, Farrington, Paul, primary, Bell, Sigourney, primary, Falenta, Katarzyna, primary, Gibbons, Francis D., primary, Lindsay, Nicola, primary, Smith, Aaron, primary, Wilson, Joanne, primary, Roberts, Karen, primary, Tonge, Michael, primary, Hopcroft, Philip, primary, Willis, Sophie E., primary, Roudier, Martine P., primary, Rooney, Claire, primary, Coker, Elizabeth A., primary, Jaaks, Patricia, primary, Garnett, Mathew J., primary, Fawell, Stephen E., primary, Jones, Clifford D., primary, Ward, Richard A., primary, Simpson, Iain, primary, Cosulich, Sabina C., primary, Pease, J. Elizabeth, primary, and Smith, Paul D., primary

Published
2023
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24. Supplementary Figure 5 from AZD0364 Is a Potent and Selective ERK1/2 Inhibitor That Enhances Antitumor Activity in KRAS-Mutant Tumor Models when Combined with the MEK Inhibitor, Selumetinib

Author

Flemington, Vikki, primary, Davies, Emma J., primary, Robinson, David, primary, Sandin, Linda C., primary, Delpuech, Oona, primary, Zhang, Pei, primary, Hanson, Lyndsey, primary, Farrington, Paul, primary, Bell, Sigourney, primary, Falenta, Katarzyna, primary, Gibbons, Francis D., primary, Lindsay, Nicola, primary, Smith, Aaron, primary, Wilson, Joanne, primary, Roberts, Karen, primary, Tonge, Michael, primary, Hopcroft, Philip, primary, Willis, Sophie E., primary, Roudier, Martine P., primary, Rooney, Claire, primary, Coker, Elizabeth A., primary, Jaaks, Patricia, primary, Garnett, Mathew J., primary, Fawell, Stephen E., primary, Jones, Clifford D., primary, Ward, Richard A., primary, Simpson, Iain, primary, Cosulich, Sabina C., primary, Pease, J. Elizabeth, primary, and Smith, Paul D., primary

Published
2023
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25. Supplementary Figure Legends from AZD0364 Is a Potent and Selective ERK1/2 Inhibitor That Enhances Antitumor Activity in KRAS-Mutant Tumor Models when Combined with the MEK Inhibitor, Selumetinib

Author

Flemington, Vikki, primary, Davies, Emma J., primary, Robinson, David, primary, Sandin, Linda C., primary, Delpuech, Oona, primary, Zhang, Pei, primary, Hanson, Lyndsey, primary, Farrington, Paul, primary, Bell, Sigourney, primary, Falenta, Katarzyna, primary, Gibbons, Francis D., primary, Lindsay, Nicola, primary, Smith, Aaron, primary, Wilson, Joanne, primary, Roberts, Karen, primary, Tonge, Michael, primary, Hopcroft, Philip, primary, Willis, Sophie E., primary, Roudier, Martine P., primary, Rooney, Claire, primary, Coker, Elizabeth A., primary, Jaaks, Patricia, primary, Garnett, Mathew J., primary, Fawell, Stephen E., primary, Jones, Clifford D., primary, Ward, Richard A., primary, Simpson, Iain, primary, Cosulich, Sabina C., primary, Pease, J. Elizabeth, primary, and Smith, Paul D., primary

Published
2023
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26. Data from AZD0364 Is a Potent and Selective ERK1/2 Inhibitor That Enhances Antitumor Activity in KRAS-Mutant Tumor Models when Combined with the MEK Inhibitor, Selumetinib

Author

Flemington, Vikki, primary, Davies, Emma J., primary, Robinson, David, primary, Sandin, Linda C., primary, Delpuech, Oona, primary, Zhang, Pei, primary, Hanson, Lyndsey, primary, Farrington, Paul, primary, Bell, Sigourney, primary, Falenta, Katarzyna, primary, Gibbons, Francis D., primary, Lindsay, Nicola, primary, Smith, Aaron, primary, Wilson, Joanne, primary, Roberts, Karen, primary, Tonge, Michael, primary, Hopcroft, Philip, primary, Willis, Sophie E., primary, Roudier, Martine P., primary, Rooney, Claire, primary, Coker, Elizabeth A., primary, Jaaks, Patricia, primary, Garnett, Mathew J., primary, Fawell, Stephen E., primary, Jones, Clifford D., primary, Ward, Richard A., primary, Simpson, Iain, primary, Cosulich, Sabina C., primary, Pease, J. Elizabeth, primary, and Smith, Paul D., primary

Published
2023
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27. Supplementary Figure 4 from AZD0364 Is a Potent and Selective ERK1/2 Inhibitor That Enhances Antitumor Activity in KRAS-Mutant Tumor Models when Combined with the MEK Inhibitor, Selumetinib

Author

Flemington, Vikki, primary, Davies, Emma J., primary, Robinson, David, primary, Sandin, Linda C., primary, Delpuech, Oona, primary, Zhang, Pei, primary, Hanson, Lyndsey, primary, Farrington, Paul, primary, Bell, Sigourney, primary, Falenta, Katarzyna, primary, Gibbons, Francis D., primary, Lindsay, Nicola, primary, Smith, Aaron, primary, Wilson, Joanne, primary, Roberts, Karen, primary, Tonge, Michael, primary, Hopcroft, Philip, primary, Willis, Sophie E., primary, Roudier, Martine P., primary, Rooney, Claire, primary, Coker, Elizabeth A., primary, Jaaks, Patricia, primary, Garnett, Mathew J., primary, Fawell, Stephen E., primary, Jones, Clifford D., primary, Ward, Richard A., primary, Simpson, Iain, primary, Cosulich, Sabina C., primary, Pease, J. Elizabeth, primary, and Smith, Paul D., primary

Published
2023
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28. Supplementary Figure 3 from AZD0364 Is a Potent and Selective ERK1/2 Inhibitor That Enhances Antitumor Activity in KRAS-Mutant Tumor Models when Combined with the MEK Inhibitor, Selumetinib

Author

Flemington, Vikki, primary, Davies, Emma J., primary, Robinson, David, primary, Sandin, Linda C., primary, Delpuech, Oona, primary, Zhang, Pei, primary, Hanson, Lyndsey, primary, Farrington, Paul, primary, Bell, Sigourney, primary, Falenta, Katarzyna, primary, Gibbons, Francis D., primary, Lindsay, Nicola, primary, Smith, Aaron, primary, Wilson, Joanne, primary, Roberts, Karen, primary, Tonge, Michael, primary, Hopcroft, Philip, primary, Willis, Sophie E., primary, Roudier, Martine P., primary, Rooney, Claire, primary, Coker, Elizabeth A., primary, Jaaks, Patricia, primary, Garnett, Mathew J., primary, Fawell, Stephen E., primary, Jones, Clifford D., primary, Ward, Richard A., primary, Simpson, Iain, primary, Cosulich, Sabina C., primary, Pease, J. Elizabeth, primary, and Smith, Paul D., primary

Published
2023
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29. Supplementary Table 3 from AZD0364 Is a Potent and Selective ERK1/2 Inhibitor That Enhances Antitumor Activity in KRAS-Mutant Tumor Models when Combined with the MEK Inhibitor, Selumetinib

Author

Flemington, Vikki, primary, Davies, Emma J., primary, Robinson, David, primary, Sandin, Linda C., primary, Delpuech, Oona, primary, Zhang, Pei, primary, Hanson, Lyndsey, primary, Farrington, Paul, primary, Bell, Sigourney, primary, Falenta, Katarzyna, primary, Gibbons, Francis D., primary, Lindsay, Nicola, primary, Smith, Aaron, primary, Wilson, Joanne, primary, Roberts, Karen, primary, Tonge, Michael, primary, Hopcroft, Philip, primary, Willis, Sophie E., primary, Roudier, Martine P., primary, Rooney, Claire, primary, Coker, Elizabeth A., primary, Jaaks, Patricia, primary, Garnett, Mathew J., primary, Fawell, Stephen E., primary, Jones, Clifford D., primary, Ward, Richard A., primary, Simpson, Iain, primary, Cosulich, Sabina C., primary, Pease, J. Elizabeth, primary, and Smith, Paul D., primary

Published
2023
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30. Supplementary Figure 6 from AZD0364 Is a Potent and Selective ERK1/2 Inhibitor That Enhances Antitumor Activity in KRAS-Mutant Tumor Models when Combined with the MEK Inhibitor, Selumetinib

Author

Flemington, Vikki, primary, Davies, Emma J., primary, Robinson, David, primary, Sandin, Linda C., primary, Delpuech, Oona, primary, Zhang, Pei, primary, Hanson, Lyndsey, primary, Farrington, Paul, primary, Bell, Sigourney, primary, Falenta, Katarzyna, primary, Gibbons, Francis D., primary, Lindsay, Nicola, primary, Smith, Aaron, primary, Wilson, Joanne, primary, Roberts, Karen, primary, Tonge, Michael, primary, Hopcroft, Philip, primary, Willis, Sophie E., primary, Roudier, Martine P., primary, Rooney, Claire, primary, Coker, Elizabeth A., primary, Jaaks, Patricia, primary, Garnett, Mathew J., primary, Fawell, Stephen E., primary, Jones, Clifford D., primary, Ward, Richard A., primary, Simpson, Iain, primary, Cosulich, Sabina C., primary, Pease, J. Elizabeth, primary, and Smith, Paul D., primary

Published
2023
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32. Optimization of a series of novel, potent and selective Macrocyclic SYK inhibitors

Author

Grimster, Neil P., Gingipalli, Lakshmaiah, Balazs, Amber, Barlaam, Bernard, Boiko, Scott, Boyd, Scott, Dry, Hannah, Goldberg, Frederick W., Ikeda, Tim, Johnson, Tony, Kawatkar, Sameer, Kemmitt, Paul, Lamont, Scott, Lorthioir, Olivier, Mfuh, Adelphe, Patel, Joe, Pike, Andy, Read, Jon, Romero, Romulo, Sarkar, Ujjal, Sha, Li, Simpson, Iain, Song, Kun, Su, Qibin, Wang, Haixia, Watson, David, Wu, Allan, Zehnder, Troy E., Zheng, XiaoLan, Li, Shaolu, Dong, Zhiqiang, Yang, Dejian, Song, Yanwei, Wang, Peng, Liu, Xuemei, Dowling, James E., and Edmondson, Scott D.

Published
2023
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33. Optimization of a Series of Novel, Potent and Selective Macrocyclic SYK Inhibitors

Author

Grimster, Neil Patrick, primary, Gingipalli, Lakshmaiah, additional, Balazs, Amber, additional, Barlaam, Bernard, additional, Boiko, Scott, additional, Boyd, Scott, additional, Dry, Hannah, additional, Goldberg, Frederick W., additional, Ikeda, Tim, additional, Johnson, Tony, additional, Kawatkar, Sameer, additional, Kemmitt, Paul, additional, Lamont, Scott, additional, Lorthioir, Olivier, additional, Mfuh, Adelphe, additional, Patel, Joe, additional, Pike, Andy, additional, Read, Jon, additional, Romero, Romulo, additional, Sarkar, Ujjal, additional, Sha, Li, additional, Simpson, Iain, additional, Song, Kun, additional, Su, Qibin, additional, Wang, Haixia, additional, Watson, David, additional, Wu, Allan, additional, Zehnder, Troy E., additional, Zheng, XiaoLan, additional, Li, Shaolu, additional, Dong, Zhiqiang, additional, Yang, Dejian, additional, Song, Yanwei, additional, Wang, Peng, additional, Liu, Xuemei, additional, Dowling, James E., additional, and Edmondson, Scott D., additional

Published
2023
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35. 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS)

Author

Aboyans, Victor, Ricco, Jean-Baptiste, Bartelink, Marie-Louise E. L., Björck, Martin, Brodmann, Marianne, Cohnert, Tina, Collet, Jean-Philippe, Czerny, Martin, De Carlo, Marco, Debus, Sebastian, Espinola-Klein, Christine, Kahan, Thomas, Kownator, Serge, Mazzolai, Lucia, Naylor, A Ross, Roffi, Marco, Röther, Joachim, Sprynger, Muriel, Tendera, Michal, Tepe, Gunnar, Venermo, Maarit, Vlachopoulos, Charalambos, Desormais, Ileana, Widimsky, Petr, Kolh, Philippe, Agewall, Stefan, Bueno, Héctor, Coca, Antonio, De Borst, Gert J., Delgado, Victoria, Dick, Florian, Erol, Cetin, Ferrini, Marc, Kakkos, Stavros, Katus, Hugo A., Knuuti, Juhani, Lindholt, Jes, Mattle, Heinrich, Pieniazek, Piotr, Piepoli, Massimo Francesco, Scheinert, Dierk, Sievert, Horst, Simpson, Iain, Sulzenko, Jakub, Tamargo, Juan, Tokgozoglu, Lale, Torbicki, Adam, Tsakountakis, Nikolaos, Tuñón, José, De Ceniga, Melina Vega, Windecker, Stephan, Zamorano, Jose Luis, Barbato, Emanuele, Coman, Ioan Mircea, Dean, Veronica, Fitzsimons, Donna, Gaemperli, Oliver, Hindricks, Gerhard, Iung, Bernard, Juni, Peter, Lancellotti, Patrizio, Leclercq, Christophe, McDonagh, Theresa, Ponikowski, Piotr, Richter, Dimitrios J., Shlyakhto, Evgeny, Simpson, Iain A., Zelveian, Parounak H., Haumer, Markus, Isachkin, Dzmitry, De Backer, Tine, Dilic, Mirza, Petrov, Ivo, Kirhmajer, Majda Vrkic, Karetova, Debora, Prescott, Eva, Soliman, Hamdy, Paapstel, Ants, Makinen, Kimmo, Tosev, Slavco, Messas, Emmanuel, Pagava, Zurab, Müller, Oliver J., Naka, Katerina K., Járai, Zoltán, Gudjonsson, Thorbjorn, Jonas, Michael, Novo, Salvatore, Ibrahimi, Pranvera, Lunegova, Olga, Dzerve, Vilnis, Misonis, Nerijus, Beissel, Jean, Pllaha, Elton, Taberkant, Mustapha, Bakken, Torbjørn, Teles, Rui, Lighezan, Daniel, Konradi, Alexandra, Zavatta, Marco, Madaric, Juraj, Fras, Zlatko, Melchor, Lorenzo Silva, Näslund, Ulf, Amann-Vesti, Beatrice, Obiekezie, Agu, Aboyans, Victor, Ricco, Jean-Baptiste, Bartelink, Marie-Louise E.L., Björck, Martin, Brodmann, Marianne, Cohnert, Tina, Collet, Jean-Philippe, Czerny, Martin, De Carlo, Marco, Debus, Sebastian, Espinola-Klein, Christine, Kahan, Thoma, Kownator, Serge, Mazzolai, Lucia, Naylor, A Ro, Roffi, Marco, Röther, Joachim, Sprynger, Muriel, Tendera, Michal, Tepe, Gunnar, Venermo, Maarit, Vlachopoulos, Charalambo, Desormais, Ileana, Widimsky, Petr, Kolh, Philippe, Agewall, Stefan, Bueno, Héctor, Coca, Antonio, De Borst, Gert J., Delgado, Victoria, Dick, Florian, Erol, Cetin, Ferrini, Marc, Kakkos, Stavro, Katus, Hugo A., Knuuti, Juhani, Lindholt, Je, Mattle, Heinrich, Pieniazek, Piotr, Piepoli, Massimo Francesco, Scheinert, Dierk, Sievert, Horst, Simpson, Iain, Sulzenko, Jakub, Tamargo, Juan, Tokgozoglu, Lale, Torbicki, Adam, Tsakountakis, Nikolao, Tuñón, José, De Ceniga, Melina Vega, Windecker, Stephan, Zamorano, Jose Lui, Barbato, Emanuele, Coman, Ioan Mircea, Dean, Veronica, Fitzsimons, Donna, Gaemperli, Oliver, Hindricks, Gerhard, Iung, Bernard, Juni, Peter, Lancellotti, Patrizio, Leclercq, Christophe, McDonagh, Theresa, Ponikowski, Piotr, Richter, Dimitrios J., Shlyakhto, Evgeny, Simpson, Iain A., Zelveian, Parounak H., Haumer, Marku, Isachkin, Dzmitry, De Backer, Tine, Dilic, Mirza, Petrov, Ivo, Kirhmajer, Majda Vrkic, Karetova, Debora, Prescott, Eva, Soliman, Hamdy, Paapstel, Ant, Makinen, Kimmo, Tosev, Slavco, Messas, Emmanuel, Pagava, Zurab, Müller, Oliver J., Naka, Katerina K., Járai, Zoltán, Gudjonsson, Thorbjorn, Jonas, Michael, Novo, Salvatore, Ibrahimi, Pranvera, Lunegova, Olga, Dzerve, Vilni, Misonis, Neriju, Beissel, Jean, Pllaha, Elton, Taberkant, Mustapha, Bakken, Torbjørn, Teles, Rui, Lighezan, Daniel, Konradi, Alexandra, Zavatta, Marco, Madaric, Juraj, Fras, Zlatko, Melchor, Lorenzo Silva, Näslund, Ulf, Amann-Vesti, Beatrice, and Obiekezie, Agu

Subjects
medicine.medical_specialty, Carotid artery disease, business.industry, Atherosclerotic disease, Upper extremity artery disease, Guideline, 030204 cardiovascular system & hematology, Vascular surgery, Lower extremity artery disease, Multisite artery disease, Peripheral Arterial Diseases, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, Renal artery disease, Internal medicine, Peripheral arterial disease, medicine, Cardiology, Mesenteric artery disease, 030212 general & internal medicine, Vertebral artery disease, Cardiology and Cardiovascular Medicine, business
Abstract

2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS) : Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries

Published
2017
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36. 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS

Author

Valgimigli, Marco, Bueno, Héctor, Byrne, Robert A., Collet, Jean-Philippe, Costa, Francesco, Jeppsson, Anders, Jüni, Peter, Kastrati, Adnan, Kolh, Philippe, Mauri, Laura, Montalescot, Gilles, Neumann, Franz-Josef, Petricevic, Mate, Roffi, Marco, Steg, Philippe Gabriel, Windecker, Stephan, Zamorano, Jose Luis, Levine, Glenn N., Badimon, Lina, Vranckx, Pascal, Agewall, Stefan, Andreotti, Felicita, Antman, Elliott, Barbato, Emanuele, Bassand, Jean-Pierre, Bugiardini, Raffaele, Cikirikcioglu, Mustafa, Cuisset, Thomas, De Bonis, Michele, Delgado, Victora, Fitzsimons, Donna, Gaemperli, Oliver, Galiè, Nazzareno, Gilard, Martine, Hamm, Christian W, Ibanez, Borja, Iung, Bernard, James, Stefan, Knuuti, Juhani, Landmesser, Ulf, Leclercq, Christophe, Lettino, Maddalena, Lip, Gregory, Piepoli, Massimo Francesco, Pierard, Luc, Schwerzmann, Markus, Sechtem, Udo, Simpson, Iain A, Uva, Miguel Sousa, Stabile, Eugenio, Storey, Robert F, Tendera, Michal, Van de Werf, Frans, Verheugt, Freek, and Aboyans, Victor

Published
2018
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37. Corrigendum to ‘2017 ESC/EACTS Guidelines for the management of valvular heart disease’ [Eur J Cardiothorac Surg 2017;52:616-664]†

Author

Falk, Volkmar, Baumgartner, Helmut, Bax, Jeroen J., De Bonis, Michele, Hamm, Christian, Holm, Per Johan, Iung, Bernard, Lancellotti, Patrizio, Lansac, Emmanuel, Muñoz, Daniel Rodriguez, Rosenhek, Raphael, Sjögren, Johan, Mas, Pilar Tornos, Vahanian, Alec, Walther, Thomas, Wendler, Olaf, Windecker, Stephan, Zamorano, Jose Luis, Roffi, Marco, Alfieri, Ottavio, Agewall, Stefan, Ahlsson, Anders, Barbato, Emanuele, Bueno, Héctor, Collet, Jean-Philippe, Coman, Ioan Mircea, Czerny, Martin, Delgado, Victoria, Fitzsimons, Donna, Folliguet, Thierry, Gaemperli, Oliver, Habib, Gilbert, Harringer, Wolfgang, Haude, Michael, Hindricks, Gerhard, Katus, Hugo A., Knuuti, Juhani, Kolh, Philippe, Leclercq, Christophe, McDonagh, Theresa A., Piepoli, Massimo Francesco, Pierard, Luc A., Ponikowski, Piotr, Rosano, Giuseppe M.C., Ruschitzka, Frank, Shlyakhto, Evgeny, Simpson, Iain A., Sousa-Uva, Miguel, Stepinska, Janina, Tarantini, Giuseppe, Tchétché, Didier, and Aboyans, Victor

Published
2017
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38. 2017 ESC/EACTS Guidelines for the management of valvular heart disease

Author

Falk, Volkmar, Baumgartner, Helmut, Bax, Jeroen J., De Bonis, Michele, Hamm, Christian, Holm, Per Johan, Iung, Bernard, Lancellotti, Patrizio, Lansac, Emmanuel, Muñoz, Daniel Rodriguez, Rosenhek, Raphael, Sjögren, Johan, Mas, Pilar Tornos, Vahanian, Alec, Walther, Thomas, Wendler, Olaf, Windecker, Stephan, Zamorano, Jose Luis, Roffi, Marco, Alfieri, Ottavio, Agewall, Stefan, Ahlsson, Anders, Barbato, Emanuele, Bueno, Héctor, Collet, Jean-Philippe, Coman, Ioan Mircea, Czerny, Martin, Delgado, Victoria, Fitzsimons, Donna, Folliguet, Thierry, Gaemperli, Oliver, Habib, Gilbert, Harringer, Wolfgang, Haude, Michael, Hindricks, Gerhard, Katus, Hugo A., Knuuti, Juhani, Kolh, Philippe, Leclercq, Christophe, McDonagh, Theresa A., Piepoli, Massimo Francesco, Pierard, Luc A., Ponikowski, Piotr, Rosano, Giuseppe M.C., Ruschitzka, Frank, Shlyakhto, Evgeny, Simpson, Iain A., Sousa-Uva, Miguel, Stepinska, Janina, Tarantini, Giuseppe, Tchétché, Didier, and Aboyans, Victor

Published
2017
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41. Discovery and Optimization of Triazolopyrimidinone Derivatives as Selective NLRP3 Inflammasome Inhibitors

Author

Harrison, David, primary, Bock, Mark G., additional, Doedens, John R., additional, Gabel, Christopher A., additional, Holloway, M. Katharine, additional, Lewis, Arwel, additional, Scanlon, Jane, additional, Sharpe, Andrew, additional, Simpson, Iain D., additional, Smolak, Pamela, additional, Wishart, Grant, additional, and Watt, Alan P., additional

Published
2022
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42. 169 High-sensitivity troponin is a biomarker of medium term mortality in 20,000 consecutive hospital patients undergoing a blood test for any reason

Author

Hinton, Jonathan, primary, Mariathas, Mark, additional, Gabara, Lavinia, additional, Allan, Rick, additional, Nicholas, Zoe, additional, Kwok, Chun Shing, additional, Ramamoorthy, Sanjay, additional, Calver, Alison, additional, Corbett, Simon, additional, Rawlins, John, additional, Simpson, Iain, additional, Wilkinson, James, additional, Sirohi, Rohit, additional, Mahmoudi, Michael, additional, Martin, Glen, additional, Cook, Paul, additional, Mamas, Mamas, additional, and Curzen, Nick, additional

Published
2022
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43. Guía ESC 2017 sobre el diagnóstico y tratamiento de la enfermedad arterial periférica, desarrollada en colaboración con la European Society for Vascular Surgery (ESVS)

Author

Aboyans, Victor, Ricco, Jean-Baptiste, Bartelink, Marie-Louise E.L., Björck, Martin, Brodmann, Marianne, Cohnert, Tina, Collet, Jean-Philippe, Czerny, Martin, Carlo, Marco De, Debus, Sebastian, Espinola-Klein, Christine, Kahan, Thomas, Kownator, Serge, Mazzolai, Lucia, Naylor, A. Ross, Roffi, Marco, Röther, Joachim, Sprynger, Muriel, Tendera, Michal, Tepe, Gunnar, Venermo, Maarit, Vlachopoulos, Charalambos, Desormais, Ileana, Widimsky, Petr, Kolh, Philippe, Agewall, Stefan, Bueno, Héctor, Coca, Antonio, De Borst, Gert J., Delgado, Victoria, Dick, Florian, Erol, Cetin, Ferrini, Marc, Kakkos, Stavros, Katus, Hugo A., Knuuti, Juhani, Lindholt, Jes, Mattle, Heinrich, Pieniazek, Piotr, Piepoli, Massimo Francesco, Scheinert, Dierk, Sievert, Horst, Simpson, Iain, Sulzenko, Jakub, Tamargo, Juan, Tokgozoglu, Lale, Torbicki, Adam, Tsakountakis, Nikolaos, Tuñón, José, Ceniga, Melina Vega de, Windecker, Stephan, and Zamorano, José Luis

Published
2018
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44. Guía ESC/EACTS 2017 sobre el tratamiento de las valvulopatías

Author

Baumgartner, Helmut, Falk, Volkmar, Bax, Jeroen J., Bonis, Michele De, Hamm, Christian, Holm, Per Johan, Iung, Bernard, Lancellotti, Patrizio, Lansac, Emmanuel, Muñoz, Daniel Rodríguez, Rosenhek, Raphael, Sjögren, Johan, Mas, Pilar Tornos, Vahanian, Alec, Walther, Thomas, Wendler, Olaf, Windecker, Stephan, Zamorano, José Luis, Roffi, Marco, Alfieri, Ottavio, Agewall, Stefan, Ahlsson, Anders, Barbato, Emanuele, Bueno, Héctor, Collet, Jean Philippe, Coman, Ioan Mircea, Czerny, Martin, Delgado, Victoria, Fitzsimons, Donna, Folliguet, Thierry, Gaemperli, Oliver, Habib, Gilbert, Harringer, Wolfgang, Haude, Michael, Hindricks, Gerhard, Katus, Hugo A., Knuuti, Juhani, Kolh, Philippe, Leclercq, Christophe, McDonagh, Theresa A., Piepoli, Massimo Franciasco, Pierard, Luc A., Ponikowski, Piotr, Rosano, Giuseppe M.C., Ruschitzka, Frank, Shlyakhto, Evgeny, Simpson, Iain A., Sousa–Uva, Miguel, Stepinska, Janina, Tarantini, Giuseppe, Tchétché, Didier, and Aboyans, Victor

Published
2018
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45. Actualización ESC 2017 sobre el tratamiento antiagregante plaquetario doble en la enfermedad coronaria, desarrollada en colaboración con la EACTS

Author

Valgimigli, Autores/miembros del Grupo de Trabajo: Marco, Bueno, Héctor, Byrne, Robert A., Collet, Jean-Philippe, Costa, Francesco, Jeppsson, Anders, Jüni, Peter, Kastrati, Adnan, Kolh, Philippe, Mauri, Laura, Montalescot, Gilles, Neumann, Franz-Josef, Petricevic, Mate, Roffi, Marco, Steg, Philippe Gabriel, Windecker, Stephan, Zamorano, José Luis, Levine, Colaborador adicional: Glenn N., Badimon, Revisores del documento: Lina, Vranckx, Pascal, Agewall, Stefan, Andreotti, Felicita, Antman, Elliott, Barbato, Emanuele, Bassand, Jean-Pierre, Bugiardini, Raffaele, Cikirikcioglu, Mustafa, Cuisset, Thomas, De Bonis, Michele, Delgado, Victora, Fitzsimons, Donna, Gaemperli, Oliver, Galiè, Nazzareno, Gilard, Martine, Hamm, Christian W., Ibáñez, Borja, Iung, Bernard, James, Stefan, Knuuti, Juhani, Landmesser, Ulf, Leclercq, Christophe, Lettino, Maddalena, Lip, Gregory, Piepoli, Massimo Francesco, Pierard, Luc, Schwerzmann, Markus, Sechtem, Udo, Simpson, Iain A., Uva, Miguel Sousa, Stabile, Eugenio, Storey, Robert F., Tendera, Michal, Van de Werf, Frans, Verheugt, Freek, and Aboyans, Victor

Published
2018
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48. Guía ESC 2017 sobre el tratamiento del infarto agudo de miocardio en pacientes con elevación del segmento ST

Author

Ibáñez, Borja, James, Stefan, Agewall, Stefan, Antunes, Manuel J., Bucciarelli-Ducci, Chiara, Bueno, Héctor, Caforio, Alida L.P., Crea, Filippo, Goudevenos, John A., Halvorsen, Sigrun, Hindricks, Gerhard, Kastrati, Adnan, Lenzen, Mattie J., Prescott, Eva, Roffi, Marco, Valgimigli, Marco, Varenhorst, Christoph, Vranckx, Pascal, Widimsk, Petr, Collet, Jean-Philippe, Kristensen, Steen Dalby, Aboyans, Victor, Baumbach, Andreas, Bugiardini, Raffaele, Mircea Coman, Ioan, Delgado, Victoria, Fitzsimons, Donna, Gaemperli, Oliver, Gershlick, Anthony H., Gielen, Stephan, Harjola, Veli-Pekka, Katus, Hugo A., Knuuti, Juhani, Kolh, Philippe, Leclercq, Christophe, Lip, Gregory Y.H., Morais, Joao, Neskovic, Aleksandar N., Neumann, Franz-Josef, Niessner, Alexander, Piepoli, Massimo Francesco, Richter, Dimitrios J., Shlyakhto, Evgeny, Simpson, Iain A., Steg, Gabriel, Terkelsen, Christian Juhl, Thygesen, Kristian, Windecker, Stephan, Zamorano, José Luis, and Zeymer, Uwe

Published
2017
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