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17 results on '"Sim, M.S."'

4. A revenue management model for sea cargo

Author

Lee, L.H., Chew, E.P., and Sim, M.S.

Subjects
Revenue -- Management, Business -- Models, Business -- Methods, Business -- Usage, Company business management, Company financing, Business, general, Engineering and manufacturing industries
Abstract

Byline: L.H. Lee, E.P. Chew, M.S. Sim In this paper, we introduce a revenue management model for an ocean carrier with two classes of orders, namely the ad hoc orders and the contractual orders. When the contractual order is accepted, the carrier can either deliver it immediately or postpone to the next ship on the shipping schedule. This problem is formulated as a stochastic dynamic programming model. We show the existence of the optimal threshold policy. Some important properties of the threshold policy are discussed. Finally, the numerical result shows that the percentage improvement of the threshold policy over an existing policy may be as high as 199%.

Published
2009

5. Smad4 expression in gastric adenoma and adenocarcinoma: Frequent loss of expression in diffuse type of gastric adenocarcinoma

Author

Kim, J.Y., Park, D.Y., Kim, G.H., Choi, K.U., Lee, Chian-Her, Huh, G.Y., Sol, M.Y., Song, G.A., Jeon, T.Y., Kim, D.H., and Sim, M.S.

Subjects
animal structures, integumentary system, Gastric adenocarcinoma, embryonic structures, digestive, oral, and skin physiology, 6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología [CDU], Gastric adenoma, digestive system diseases
Abstract

Smads are signal transducers for the members of the TGF-ß superfamily. Of these Smads, Smad4 is essential for TGF-ß signaling. The purpose of this study was to elucidate Smad4 expression and localization in 65 gastric adenomas, 49 intestinal-type and 39 diffuse type of gastric adenocarcinomas (including 12 cases of fresh frozen tissue) using Realtime RT-PCR and immunohistochemistry. Real-time RTPCR showed that intestinal type gastric adenocarcinomas have higher Smad4 mRNA expression than diffuse type gastric adenocarcinomas. Immunohistochemical stain for Smad4 revealed that expression of Smad4 was significantly lower in diffusetype gastric adenocarcinoma than intestinal-type gastric adenocarcinomas. Also, higher Smad4 protein expression in intestinal type gastric adenocarcinomas than overall gastric adenoma was noted. The rate of reduced Smad4 expression was higher in advanced gastric cancer than early gastric cancer. These results suggest that Smad4 might play different roles in human gastric carcinogenesis, especially between intestinal type and diffuse type of gastric adenocarcinoma.

Published
2005

12. Validation of the termination guideline for out of hospital arrest of Korea

Author

Eun, J.G., primary, Kwon, M.K., additional, Park, Sh., additional, Shin, J.S., additional, Kim, M.J., additional, Chung, S.P., additional, Lee, H.S., additional, Na, J.U., additional, Lee, Y.H., additional, Chang, H.W., additional, Shin, T.G., additional, Sim, M.S., additional, Jo, I.J., additional, Song, H.G., additional, and Song, K.J., additional

Published
2010
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14. Identification of levels of maternal HIV-1 RNA associated with risk of perinatal transmission: effect of maternal zidovudine treatment on viral load

Author

Dickover, R.E., Garratty, E.M., Herman, S.A., Sim, M.S., Plaeger, S., Boyer, P.J., Keller, M., Deveikis, A., Stiehm, E.R., and Bryson, Y.J.

Subjects
HIV (Viruses), HIV infection in pregnancy, Zidovudine -- Evaluation
Abstract

According to the authors' abstract of an article published in JAMA - Journal of the American Medical Association, "OBJECTIVE: To determine if there are levels of human immunodeficiency virus type [...]

Published
1996

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