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espanolIntroduccion. En Peru, los trastornos hipertensivos del embarazo son la segunda causa de mortalidad materna. Objetivo. La presente guia de practica clinica basada en evidencias (GPC-BE)brinda recomendaciones para la prevencion y tratamiento de la pre-eclampsia y eclampsia. Metodos. Se elaboro una GPC-BE adaptada mediante unproceso sistematico, riguroso y transparentecon un grupo elaborador conformado por metodologos y profesionales de la salud expertos en el manejo de la enfermedad. La guia cuenta con dieciseis preguntas clinicas y dieciseis recomendaciones. Se realizo la busqueda y preseleccion de GPC, las mismas que fueron evaluadas mediante el instrumento “Appraisal of Guidelines for Research and Evaluation II” (AGREE-II), para su adaptacion. La busqueda sistematica de evidencias para responder las preguntas clinicas se realizo en multiples bases de datos: MEDLINE/PubMed, EMBASE/Ovid, Cochrane Library, LILACS y SciELO. Las evidencias fueron seleccionadas y analizadas criticamente por pares clinicos y metodologicos; las recomendaciones fueron elaboradas mediante la metodologia Grading of Recommendations Assessment, Development, and Evaluation (GRADE). Resultados. Con la participacion de un panel de expertos clinicos del Instituto Nacional Materno Perinatal, redes de salud y otras instituciones de referencia, se elaboraron 16 recomendaciones dirigidas a la prevencion y tratamiento de mujeres gestantes en riesgo de pre-eclampsia, gestantes con pre-eclampsia, eclampsia o enfermedad hipertensiva. Conclusiones. Este articulo resume la guia de practica clinica basada en evidencias para la prevencion y tratamiento de pre-eclampsia y eclampsia en gestantes en el instituto de referencia nacional en salud materna y neonatal del Peru. EnglishIntroduction. In Peru, hypertensive disorders of pregnancy are the second cause of maternal mortality. Objective. This evidence-based clinical practice guideline (EB-CPG) provides recommendations for the prevention and treatment of pre-eclampsia and eclampsia. Methods. An adapted EB-CPG was elaborated through a systematic, rigorous and transparent process with a group consisting of methodologists and health professionals who are experts in the management of the disease. The guide has sixteen clinical questions and sixteen recommendations. The search and pre-selection of EB-CPGs were performed, which were evaluated through the “Appraisal of Guidelines for Research and Evaluation II” tool (AGREE-II), for its adaptation. The systematic search for evidence to answer the 16 clinical questions were made in multiple databases: MEDLINE / PubMed, EMBASE / Ovid, Cochrane Library, LILACS and SciELO. Evidences were selected and analyzed critically by clinicians and methodologists in pairs, recommendations were elaborated through the Grading of Recommendations Assessment, Development, and Evaluation methodology (GRADE). Results. With the participation of a panel of clinical experts from the National Perinatal Maternal Institute, representatives from health care networks and other reference institutions, 16 recommendations were established for the prevention and treatment of pregnant women at risk of pre-eclampsia, for pregnant women with pre-eclampsia, eclampsia or hypertensive disease. Conclusions. This article summarizes the evidence-based clinical practice guidelines for the prevention and treatment of pre-eclampsia and eclampsia in peruvian pregnant women for the national reference institute for maternal and neonatal health of Peru