274 results on '"Silverman, Jared"'
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2. Perspective on Antibacterial Lead Identification Challenges and the Role of Hypothesis-Driven Strategies
3. Drug Target Validation: Lethal Infection Blocked by Inducible Peptide
4. Discovery and development of surotomycin for the treatment of Clostridium difficile
5. Inhibition of Daptomycin by Pulmonary Surfactant: In vitro Modeling and Clinical Impact
6. Randomized Study of Rivaroxaban vs Placebo on Disease Progression and Symptoms Resolution in High-Risk Adults With Mild Coronavirus Disease 2019
7. Randomized Study of Rivaroxaban vs Placebo on Disease Progression and Symptoms Resolution in High-Risk Adults With Mild Coronavirus Disease 2019.
8. Daptomycin-reversible rifampicin resistance in vancomycin-resistant Enterococcus faecium
9. Multilateral resolution over unilateral retaliation: adjudicating the use of Section 301 before the WTO.
10. Discovery of Pyrazolopyridones as a Novel Class of Gyrase B Inhibitors Using Structure Guided Design
11. Alternatives to antibiotics—a pipeline portfolio review
12. Between the Boundaries of Nineteenth-Century Scientific Psychology: Sir Alexander Morison and the Sociology of Phrenology
13. Reduced pulmonary surfactant interaction of daptomycin analogs via tryptophan replacement with alternative amino acids
14. Discovery of Azaindole Ureas as a Novel Class of Bacterial Gyrase B Inhibitors
15. Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors
16. Structure–Activity Relationship Studies of a Series of Semisynthetic Lipopeptides Leading to the Discovery of Surotomycin, a Novel Cyclic Lipopeptide Being Developed for the Treatment of Clostridium difficile-Associated Diarrhea
17. Daptomycin forms cation- and size-selective pores in model membranes
18. Surotomycin Demonstrates Low In Vitro Frequency of Resistance and Rapid Bactericidal Activity in Clostridium difficile, Enterococcus faecalis, and Enterococcus faecium
19. Cardiolipin Prevents Membrane Translocation and Permeabilization by Daptomycin
20. Additional Routes to Staphylococcus aureus Daptomycin Resistance as Revealed by Comparative Genome Sequencing, Transcriptional Profiling, and Phenotypic Studies
21. Mutual inhibition through hybrid oligomer formation of daptomycin and the semisynthetic lipopeptide antibiotic CB-182,462
22. In Vitro and In Vivo Characterization of CB-183,315, a Novel Lipopeptide Antibiotic for Treatment of Clostridium difficile
23. VraSR Two-Component Regulatory System Contributes to mprF -Mediated Decreased Susceptibility to Daptomycin in In Vivo -Selected Clinical Strains of Methicillin-Resistant Staphylococcus aureus
24. Cellular Architecture Mediates DivIVA Ultrastructure and Regulates Min Activity in Bacillus subtilis
25. Genetic Basis for Daptomycin Resistance in Enterococci
26. Evaluating the activity of the RNA polymerase inhibitor myxopyronin B against Staphylococcus aureus
27. Oligomerization of daptomycin on membranes
28. Regulation of mprF by Antisense RNA Restores Daptomycin Susceptibility to Daptomycin-Resistant Isolates of Staphylococcus aureus
29. ChemInform Abstract: A Series of Quinoline Analogues as Potent Inhibitors of C. albicans Prolyl tRNA Synthetase.
30. Genetically Engineered Lipopeptide Antibiotics Related to A54145 and Daptomycin with Improved Properties
31. Daptomycin Exerts Bactericidal Activity without Lysis of Staphylococcus aureus
32. Transcriptional Profiling Reveals that Daptomycin Induces the Staphylococcus aureus Cell Wall Stress Stimulon and Genes Responsive to Membrane Depolarization
33. Bactericidal Action of Daptomycin against Stationary-Phase and Nondividing Staphylococcus aureus Cells
34. Structure–ActivityRelationship Studies ofa Series of Semisynthetic Lipopeptides Leading to the Discovery ofSurotomycin, a Novel Cyclic Lipopeptide Being Developed for the Treatmentof Clostridium difficile-AssociatedDiarrhea.
35. Genetic Changes That Correlate with Reduced Susceptibility to Daptomycin in Staphylococcus aureus
36. A Series of Heterocyclic Inhibitors of Phenylalanyl-tRNA Synthetases with Antibacterial Activity
37. A Series of Spirocyclic Analogues as Potent Inhibitors of Bacterial Phenylalanyl‐tRNA Synthetases.
38. A series of heterocyclic inhibitors of phenylalanyl- t RNA synthetases with antibacterial activity
39. A series of spirocyclic analogues as potent inhibitors of bacterial phenylalanyl- t RNA synthetases
40. Synthesis and biological activity of N-Acylated ornithine analogues of daptomycin
41. Array synthesis of novel lipodepsipeptide
42. Analysis of Daptomycin Efficacy and Breakpoint Standards in a Murine Model ofEnterococcus faecalisandEnterococcus faeciumRenal Infection
43. In Vitro Bactericidal Activities of Daptomycin against Staphylococcus aureus and Enterococcus faecalis Are Not Mediated by Inhibition of Lipoteichoic Acid Biosynthesis
44. Correlation of Daptomycin Bactericidal Activity and Membrane Depolarization in Staphylococcus aureus
45. Resistance Studies with Daptomycin
46. A series of quinoline analogues as potent inhibitors of C. albicans prolyl tRNA synthetase
47. Induced Activation of the Toxoplasma gondiiNucleoside Triphosphate Hydrolase Leads to Depletion of Host Cell ATP Levels and Rapid Exit of Intracellular Parasites from Infected Cells
48. Liability in cyberspace — II
49. Roles of Glu 349 and Asp 352 in membrane insertion and translocation by diphtheria toxin
50. A series of heterocyclic inhibitors of phenylalanyl-tRNA synthetases with antibacterial activity
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