1. Clinical and uterine cervix characteristics of women with Mycoplasma and Ureaplasma in genital discharge.
- Author
-
Matos MS, Silva MCATD, Brito MB, and Gonçalves AK
- Subjects
- Humans, Female, Adult, Cross-Sectional Studies, Young Adult, Middle Aged, Adolescent, Vaginal Discharge microbiology, Prevalence, Papillomavirus Infections microbiology, Urinary Tract Infections microbiology, Urinary Tract Infections epidemiology, Brazil epidemiology, Vaginal Smears, Ureaplasma Infections microbiology, Ureaplasma Infections epidemiology, Mycoplasma Infections epidemiology, Mycoplasma Infections microbiology, Ureaplasma isolation & purification, Cervix Uteri microbiology, Cervix Uteri pathology, Mycoplasma isolation & purification
- Abstract
Objective: The objective of this study was to assess the clinical and uterine cervix characteristics of patients displaying vaginal discharge with positive results for Mycoplasma sp. and/or Ureaplasma spp., Methods: An analytical cross-sectional study involving women aged 18-45 years was conducted. Microbiological assessments included Ureaplasma and Mycoplasma cultures, as well as human papillomavirus hybrid capture using ecto and endocervix swabs. All tests were two-tailed, and significance was set at p<0.05., Results: Among 324 women, Ureaplasma prevalence was 17.9%, and Mycoplasma prevalence was 3.1%. The Ureaplasma-positive group exhibited a higher frequency of urinary tract infections (39.1 vs. 19%, p=0.002) and human papillomavirus (39.7 vs. 12.8%, p≤0.001) compared with controls. The Mycoplasma-positive group showed a higher frequency of non-contraceptive use compared with controls (66.2 vs. 30.0%, p=0.036). Abnormal colposcopic findings were more prevalent in the Mycoplasma/Ureaplasma-positive group than in controls (positive: 65% vs. control: 35%, p=0.001). Pap smear findings did not differ between the groups., Conclusion: Ureaplasma spp. was associated with urinary tract infections and human papillomavirus, while the presence of Mycoplasma sp. was linked to reduced contraceptive use. When analyzing both pathogens together, a higher frequency of abnormal colposcopic findings was observed, with no difference in cytological findings in the positive group.
- Published
- 2024
- Full Text
- View/download PDF