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Your search keyword '"Silva, Mauricio F."' showing total 39 results
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39 results on '"Silva, Mauricio F."'

9. Management of cancer pain in Latin America.

Author

Silva Ortiz, Víctor Manuel, Nájera Medellín, Jorge A., Adjounian Correa, Sarkis Horacio, Flores Cantisani, Jose Alberto, Lim, Fiona, Wan, Angela, and Silva, Mauricio F.

Published
2020

10. Management of cancer emergencies.

Author

Leal, Jorge Henrique, McArthur, Heather L., Lim, Fiona, Wan, Angela, Amendola, Beatriz, and Silva, Mauricio F.

Published
2020

14. Hypofractionated radiotherapy for complicated bone metastases in patients with poor performance status: a phase II international trial

Author

Silva, Mauricio F., primary, Marta, Gustavo N., additional, Lisboa, Felipe P.C., additional, Watte, Guilherme, additional, Trippa, Fabio, additional, Maranzano, Ernesto, additional, da Motta, Neiro W., additional, Popovic, Marko, additional, Ha, Tuan, additional, Burmeister, Bryan, additional, and Chow, Edward, additional

Published
2018
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17. Management of malignant gliomas.

Author

de Azevedo Rosas, Felipe, Marta, Gustavo Nader, Lim, Fiona, Wan, Bo Angela, Silva, Mauricio F., and des de Castro, Douglas Gue

Published
2019

18. Management of pediatric cancer in Latin America.

Author

Figueiredo, Maria Luísa Sucharski, de Lacerda Gonçalves Chaves, Cristiane, Chen, Michael Jenwei, Marta, Gustavo Nader, Lim, Fiona, Wan, Bo Angela, and Silva, Mauricio F.

Published
2019

27. Management of gallbladder cancer.

Author

Castillo, Felipe, de Aretxabala, Xabier, Torres-Quevedo, Rodrigo, Lim, Fiona, Wan, Bo Angela, and Silva, Mauricio F.

Published
2019

34. Hypofractionated radiotherapy for complicated bone metastases in patients with poor performance status: a phase II international trial

Author

Silva, Mauricio F., Marta, Gustavo N., Lisboa, Felipe P.C., Watte, Guilherme, Trippa, Fabio, Maranzano, Ernesto, da Motta, Neiro W., Popovic, Marko, Ha, Tuan, Burmeister, Bryan, and Chow, Edward

Abstract

Purpose: To evaluate the efficacy and safety of hypofractionated radiotherapy (16 Gy in 2 fractions, 1 week apart) in patients with complicated bone metastases and poor performance status.Methods: A prospective single-arm phase II clinical trial was conducted from July 2014 to May 2016. The primary endpoint was pain response as defined in the International Consensus on Palliative Radiotherapy Endpoints. Secondary endpoints included quality of life as measured by quality of life questionnaire (QLQ) PAL-15 and QLQ-BM22 European Organisation for Research and Treatment of Cancer guidelines, pain flare, adverse events, re-irradiation, and skeletal complications.Results: Fifty patients were enrolled. There were 23 men with a median age of 58 years (range 26-86). Of the 50 patients, 38 had an extraosseous soft tissue component, 18 needed postsurgical radiation, 3 had neuropathic pain, and 3 had an impending fracture in a weight-bearing bone. At 2 months, 33 patients were alive (66%). Four (12.5%) had a complete response and 12 (37.5%) had a partial response. A statistically significant improvement was seen in the functional interference (p = 0.01) and psychosocial aspects (p = 0.03) of the BM22. No patient had spinal cord compression. One patient required surgery for pathologic fracture, and another re-irradiation.Conclusions: Hypofractionated radiotherapy (16 Gy in 2 fractions of 8 Gy 1 week apart) achieved satisfactory pain relief and safety results in patients with complicated bone metastases and poor performance status.

Published
2019
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35. Good outcomes of liver transplantation for hepatitis C at a low volume centre.

Author

Su Yin Lau, Woodman, Richard J., Silva, Mauricio F., Muller, Kate, Libby, John, Chen, John W., Padbury, Robert, and Wigg, Alan J.

Subjects
LIVER transplantation, HEPATITIS C diagnosis, HEPATITIS C treatment, HEPATITIS C virus, HEPATITIS C, PHYSIOLOGY, PATIENTS
Abstract

Background and aims. Concerns exist about outcomes of liver transplantation (LT) from low volume centres, especially for hepatitis C (HCV) patients. The aim of the study was to assess patient outcomes as well as their predictors post LT for HCV in a small volume Australian unit (< 25 LTs/year), comparing these with the average outcomes obtained from national and international transplant registries. Patients transplanted for HCV at the South Australian Liver Transplant Unit between 1992 and 2012 were studied. Outcomes assessed were patient and graft survival at 1,3, and 5 years. Factors independently associated with the outcomes were assessed using Cox regression model. Results. 1, 3, and 5-year patient survival for HCV patients was 95.2, 82.9, and 78.2%, graft survival were 93.7, 80.1, and 75.5% respectively. The total follow-up time observed was 299.9 years amongst 61 patients in which there were 16 deaths. The expected number of deaths was 40.4 and the standardized mortality ratio 0.40 (95% CI = 0.24, 0.65). These results compared favourably to those obtained from the SRTR registry. Variables independently associated with lower patient survival: donor age (HR = 1.06, 95% CI 1.02 - 1.11; P = 0.003), and post LT cytomegalovirus (CMV) disease requiring treatment (HR = 4.03, 95% CI 1.48 - 10.92;P = 0.06). Conclusion. In conclusion, high rates of patient and graft survival for HCV liver transplantation can be obtained in a small volume unit. Young donor age and lack of CMV disease post-transplant were associated with better outcomes. Institutional factors may be influential determinants of outcomes. [ABSTRACT FROM AUTHOR]

Published
2016
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