23 results on '"Silva, Marcos R."'
Search Results
2. Evidence for a correlation between total lead concentrations in soils and the presence of geological faults
- Author
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Moreira-Silva, Marcos R., Sáenz, Carlos A. Tello, Nunes, João O. Rodrigues, Godoy, Manoel, and Teixeira, Marcos F. S.
- Published
- 2017
- Full Text
- View/download PDF
3. Pesticidas no perfil de solos em areas de plantacao de cebolas em Ituporanga, SC
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Pinheiro, Adilson, Moraes, João C.S., and da Silva, Marcos R.
- Published
- 2011
4. Influence of Rainfall Seasonality in Groundwater Chemistry at Western Region of São Paulo State—Brazil
- Author
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Maroubo, Lais A., primary, Moreira-Silva, Marcos R., additional, Teixeira, José Jerônimo, additional, and Teixeira, Marcos F. S., additional
- Published
- 2021
- Full Text
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5. Impact Features Induced by Single Fast Ions of Different Charge-State on Muscovite Mica
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Alencar, Igor, primary, Silva, Marcos R., additional, Leal, Rafael, additional, Grande, Pedro L., additional, and Papaléo, Ricardo M., additional
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- 2021
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6. Impact of emergency short‐stay unit opening on in‐hospital global and cardiology indicators
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Cirillo, Willian, primary, Freitas, Lidia R. C., additional, Kitaka, Edson L., additional, Matos‐Souza, José R., additional, Silva, Marcos R., additional, Coelho, Otávio R., additional, Coelho‐Filho, Otávio R., additional, Sposito, Andrei C., additional, and Nadruz, Wilson, additional
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- 2021
- Full Text
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7. Effect of the Incorporation of Sugarcane Bagasse Biochar in Leaching and Bioavailability of Clomazone in Soil
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Silva,Marcos R. F. da, Queiroz,Maria E. L. R. de, Neves,Antônio A., Silva,Antônio A. da, Oliveira,André F. de, Oliveira,Renan L. de, Azevedo,Mariane M., and Pereira,Gustavo A. M.
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herbicide ,agent for environmental contamination mitigation ,liquid chromatography ,greenhouse bioassay ,mobility - Abstract
Clomazone exhibits high water solubility, low sorption in soil colloids, and therefore can leach and contaminate deep layers of soil profile and groundwater. In this work, the effect of the incorporation of sugarcane bagasse biochar in leaching and bioavailability of clomazone in red latosol was evaluated. Soil samples amended with 1% (m/m) biochar were placed in different depths (0-1, 0-2.5 and 0-5 cm) on the top of polyvinyl chloride (PVC) columns filled with soil. Clomazone-based herbicide was applied, and rainfall was simulated on top of the columns. A validated chromatographic method, together with a greenhouse bioassay, were used to quantify and to evaluate the mobility and availability of clomazone along the columns. The incorporation of sugarcane bagasse biochar in the superficial layers at the column tops increased herbicide sorption, reduced its leaching and bioavailability in soil and scaled down the environmental risk of clomazone avoiding contamination of underground aquifer reservoirs.
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- 2019
8. Fatty Acid Profile of Sunflower Achene Oil From the Brazilian Semi-arid Region
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Carvalho, Claudio G. P. de, primary, Caldeira, Andressa, additional, Carvalho, Luciana M. de, additional, Carvalho, Hélio W. L. de, additional, Ribeiro, José L., additional, Mandarino, José M. G., additional, Resende, José C. F. de, additional, Santos, Ariomar R. dos, additional, Silva, Marcos R. da, additional, and Arriel, Nair H. C., additional
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- 2018
- Full Text
- View/download PDF
9. Avaliação da utilização de cloreto de cálcio em substituição ao ácido lático para fabricação de
- Author
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Conceição, Antônio C. da, Silva, Marcos R. da, Oliveira, Valesca S. de, Soares, Bruno G., Martins, Maurilio L., and Martins, Aurélia D. O.
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soro ,Evaluation of utilization of calcium chloride in substitution to lactic acid in order to produce ricotta ,lcsh:Dairy processing. Dairy products ,lcsh:SF250.5-275 ,Whey ,technology of production ,cheese ,tecnologia de fabricação ,queijo - Abstract
Milk whey is a co-product of cheese industry considered as an environmental pollutant, in spite of possessing nutrients of high biological value. Due to its functional properties, whey proteins can be used in many formulations, as in ricotta production, concentrated whey proteins, among others. The aim of this work was to evaluate the viability of ricotta production using calcium chloride in substitution to lactic acid, as well as to determine the yielding of production, physiochemical, microbiological and sensorial characteristics of the obtained cheese. Ricotta was produced using calcium chloride or lactic acid. After production, cheeses were weighted in order to determine the practical yield and samples were collected to physiochemical evaluation, and calculation of adjusted technical yield and GL coefficient. Besides, microbiological and sensorial analyses were accomplished. The obtained values for yield were significantly affected (p0,05) by the technology of ricotta production, been the utilization of calcium chloride in substitution to lactic acid promoted higher yield. The medium values of practical yield, technical yield and GL coefficient when calcium chloride was used were of 16,46; 21,35 e 106,03, respectively, on the other hand when lactic acid was used to produce ricotta the medium values were 22,75; 31,94 e 85,13, respectively. Samples of ricotta presented low counting of aerobic mesophilics microorganisms, which indicated the high microbiological quality. Besides, ricotta produced with calcium chloride presented higher preference in relation to that elaborated with lactic acid, probably, this happened due to the less acid flavor presented by the final product. Therefore, ricotta production with calcium chloride in substitution to lactic acid is viable for presenting larger yield, reduction of the production costs and good sensorial acceptance. soro de leite é um co-produto da indústria de queijos considerado como um poluidor ambiental, apesar de possuir nutrientes de elevado valor biológico. Devido às suas propriedades funcionais, as proteínas do soro podem ser usadas em muitas formulações, como na produção de ricota, concentrado protéico de soro, dentre outros. O objetivo deste trabalho foi avaliar a viabilidade de produção de ricota utilizando cloreto de cálcio em substituição ao ácido lático, bem como determinar o rendimento da produção, as características físico-química, microbiológicas e sensoriais do queijo obtido. Ricota foi produzida utilizando cloreto de cálcio ou ácido lático. Após a fabricação os queijos foram pesados para realização do cálculo do rendimento prático e foram coletadas amostras para avaliação físico-química, e cálculo do rendimento técnico ajustado e o aproveitamento final de sólidos nos queijos em relação a cada litro de soro usado na fabricação (coeficiente GL). Além disso, foi realizada análise microbiológica e sensorial. Os valores obtidos para rendimento foram afetados significativamente (p0,05) pela tecnologia de produção de ricota, sendo que a utilização de cloreto de cálcio em substituição ao ácido lático proporcionou maior rendimento. Os valores médios de rendimento prático, rendimento técnico ajustado e coeficiente GL utilizando-se cloreto de cálcio foram de 16,46; 21,35 e 106,03, respectivamente, enquanto que utilizando-se ácido lático para produção de ricota os valores médios foram de 22,75; 31,94 e 85,13, respectivamente. As amostras de ricota apresentaram baixa contagem de microrganismos mesófilos aeróbios, o que indicou a alta qualidade microbiológica do produto. Além disso, ricota produzida com cloreto de cálcio apresentou maior preferência em relação à elaborada com ácido lático, provavelmente, isto ocorreu devido ao sabor menos ácido apresentado pelo produto final. Assim, a produção de ricota com cloreto de cálcio em substituição ao ácido lático é viável, por apresentar maior rendimento, redução dos custos de produção e boa aceitação sensorial.
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- 2009
10. Regioselective preparation of thiamphenicol esters through lipase-catalyzed processes
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Silva, Marcos R. da, Montenegro, Tasso G. C., Mattos, Marcos C. de, Oliveira, Maria da Conceição F. de, Lemos, Telma L. G. de, Gonzalo, Gonzalo de, Lavandera, Iván, Gotor-Fernández, Vicente, and Gotor, Vicente
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thiamphenicol ,lipases ,biocatalysis ,regioselective processes ,medium engineering - Abstract
The lipase-catalyzed synthesis of thiamphenicol derivatives has been studied through complementary acylation and hydrolytic approaches, finding Candida antarctica lipase B as the most efficient biocatalyst for the selective modification of both thiamphenicol and thiamphenicol diacetate, respectively. The best results have been obtained using acylation reactions with different vinyl esters of variable length, yielding the corresponding 3'-monoesters with excellent yields and in short reaction times. The conditions have been analyzed in terms of substrate concentration, enzyme loading and type of acyl donor. The reuse of the enzyme for five-times without significant loss of the activity has also been demonstrated. Alternatively, the hydrolytic approach has allowed the preparation of some 1'-monoesters in good yields, although the reactivity and selectivity levels were lower than the ones achieved for the complementary acetylation reaction. A síntese de derivados do tianfenicol, catalisada por lipases, foi investigada através da realização das reações de acilação e de hidrólise, como abordagens complementares, sendo a lipase Candida antarctica B o biocatalisador mais eficiente para as modificações seletivas de ambos, o tianfenicol e o correspondente diacetato do tianfenicol, respectivamente. Os melhores resultados foram obtidos nas reações de acilação com diferentes ésteres vinílicos, contendo cadeias carbônicas de comprimento variável, levando aos correspondentes 3'-monoésteres com excelentes rendimentos e em tempos reacionais curtos. As condições reacionais foram analisadas em termos de concentração de substrato, carga de enzima e tipo de doador de acila. Foi demonstrado o reuso da enzima por cinco vezes sem perda significativa de atividade. Alternativamente, a abordagem hidrolítica propiciou a preparação de alguns 1'-monoésteres em bons rendimentos, ainda que os níveis de reatividade e seletividade foram mais baixos que os obtidos na reação complementar de acetilação.
- Published
- 2014
11. Uso da teoria de números índices para adequação de semeadoras-adubadoras de precisão
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Silva, Marcos R. da, Daniel, Luiz A., and Peche Filho, Afonso
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tomada de decisão ,plantio direto ,direct planting ,mecanização ,decision-making ,mechanization - Abstract
Com este trabalho, objetivou-se sistematizar dados contidos em um conjunto de catálogos tecnológicos referentes aos modelos de semeadoras-adubadoras de precisão disponíveis no mercado nacional, analisar as informações disponíveis, construir um banco de dados com as características técnicas e propor um índice classificatório para os modelos. Analisaram-se 93 catálogos fornecidos por fabricantes nacionais, possibilitando caracterizar 250 modelos de semeadoras-adubadoras de precisão. Com base em 31 características técnicas disponíveis nos catálogos, construiu-se um banco de dados utilizando-se nove dessas características, na formulação de um número índice denominado -Índice de Adequação- (IA). A aplicação do IA permitiu que se classificassem os 250 modelos em cinco categorias (A, B, C, D e E), sendo que 73% dos modelos analisados integraram as categorias A e B, indicadas para pequenas e médias propriedades; 19% completaram a categoria C, indicada para médias e grandes propriedades e 8% dos modelos integraram as categorias D e E, indicadas para grandes propriedades. Conclui-se, portanto, que o IA é uma ferramenta que poderá ser utilizada por produtores na tomada de decisão, para escolha da semeadora-adubadora mais adequada às características da propriedade. The objectives of this work were to systemize the data contained in a set of technical catalogues referring to models of fertilizer and seed drills of precision to analyze the available information in order to prepare a database with technical characteristics and to propose a classification index for the models based on these characteristics. 93 catalogues of fertilizer and seed drills of precision supplied by Brazilian manufacturers were analyzed for generating information to characterize 250 models. On the basis of 31 technical characteristics available in catalogues, a database was prepared in which 9 of these characteristics were used in the formulation of an index number, called -Index of Adequacy- (IA). The application of IA allowed to classify the 250 models in five different categories (A, B, C, D and E), where 73% of the analyzed models composed the categories A and B, indicated for small and medium farms; 19% composed the category C, indicated for medium and large farms; and 8% of the models composed the categories D and E, indicated for large farms. It may be concluded that the adequacy index is a tool that could be used by producers in the decision-making to select most adequate fertilizer and seed drill for farm characteristics.
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- 2007
12. Regioselective Preparation of Thiamphenicol Esters Through Lipase-Catalyzed Processes
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Silva, Marcos R. da, primary, Montenegro, Tasso G. C., additional, Mattos, Marcos C. de, additional, Oliveira, Maria da Conceição F. de, additional, Lemos, Telma L. G. de, additional, Gonzalo, Gonzalo de, additional, Lavandera, Iván, additional, Gotor-Fernández, Vicente, additional, and Gotor, Vicente, additional
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- 2014
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13. Performance of lettuce cultivars in the State of Acre, Brazil
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Lédo,Francisco J. da S., Sousa,João A. de, and Silva,Marcos R. da
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Meloidogyne javanica ,rendimento ,premature flowering resistance ,Lactuca sativa L ,resistência ao florescimento prematuro ,yield - Abstract
Devido às condições ambientais verificadas no estado do Acre, caracterizado pela ocorrência de temperaturas elevadas e alta precipitação, as cultivares tradicionalmente utilizadas pelos produtores apresentam baixo rendimento e qualidade. O objetivo do presente trabalho foi avaliar o comportamento das novas cultivares de alface disponíveis no mercado, em termos de características agronômicas e rendimento, nas condições edafoclimáticas de Rio Branco, Acre. Para isso foram realizados dois ensaios no campo experimental da Embrapa Acre, em um solo do tipo Argissolo Vermelho-Escuro, textura argilosa. O primeiro de maio a julho de 1996 (período seco) e o segundo de dezembro de 1996 a fevereiro de 1997 (período chuvoso). Foram avaliadas as cultivares Babá de Verão, Brisa, Carolina AG-576, Elisa, Lucy Brown, Marisa AG-216, Piracicaba 65, Regina 71, Tainá, Simpson, Vanessa e Verônica, sendo que 'Regina 71' e 'Elisa' foram incluídas apenas no ensaio do período seco. O delineamento experimental foi o de blocos casualizados, com três repetições. No período seco, as cultivares Simpson, Lucy Brown e Regina 71 apresentaram os maiores pesos médios (373; 362 e 341 g, respectivamente) e produções comerciais de 49,8; 48,3 e 45,5 t/ha, respectivamente. Em geral, as cultivares dos tipos lisa sem cabeça e lisa com cabeça apresentaram maior índice de ataque de nematóide (Meloidogyne javanica) quando comparadas às do tipo crespa. No ensaio realizado no período chuvoso, as cultivares Marisa AG-216, Verônica, Lucy Brown, Brisa, Tainá e Piracicaba-65 apresentaram os maiores pesos médios e produções comerciais. Entretanto, as médias obtidas foram bem inferiores às verificadas no ensaio do período seco, variando de 164 a 198 g para o peso médio, e 21,9 a 25,9 t/ha para produção comercial. Dentre as cultivares avaliadas no período seco, Regina 71 (lisa, sem cabeça) e Carolina AG-576 (lisa, com cabeça) destacaram-se entre as do tipo lisa, apresentando folhas de tamanho uniforme e bem arranjadas. Entre as de folha crespa solta destacaram-se as cultivares. Verônica e Marisa. A cultivar Lucy Brown do tipo americana (crisp head) também foi bastante produtiva. Due to the environmental conditions verified in the state of Acre, characterized by the occurrence of high temperatures and precipitation, cultivars traditionally used by the producers present low yield and poor quality. The aim of the present work was to evaluate the behavior of the new lettuce cultivars available in the market, in terms of agronomic characteristics and yield, in the climatic and soil conditions of Rio Branco. Two trials were accomplished in the Embrapa Acre experimental farm, in a dark red claysoil, of loamy texture. The first from May to July 1996 (dry season) and the second from December 1996 to February 1997 (rainy season). The cultivars Babá de Verão, Brisa, Carolina AG-576, Elisa, Lucy Brown, Marisa AG-216, Piracicaba 65, Regina 71, Tainá, Simpson, Vanessa and Verônica were evaluated. 'Regina 71' and 'Elisa' were only included on the dry season trial. The experimental design was a randomized block, with three replications. During the dry season, the cultivars Simpson, Lucy Brown and Regina 71 presented the largest average weights (373; 362 and 341 g, respectively) and commercial yields (49.8; 48.3 and 45.5 t/ha, respectively). In general, the cultivars with smooth leaves with or without head presented larger nematoid (Meloidogyne javanica) attack index, when compared to the curly type ones. In the rainy season trials, the cultivars Marisa AG-216, Verônica, Lucy Brown, Brisa, Tainá and Piracicaba-65 presented the greatest average weights and commercial yields. However, the obtained averages were very inferior to that verified in the trials of the dry period, varying from 164 to 198 g for average weight, and from 21.9 to 25.9 t/ha for commercial yield. Of those cultivars tested on the dry season, Regina 71 (butter head/less firm head) and Carolina (butter head) AG-576 stood out among the butterhead types, while Verônica, Marisa AG-216 (loose leaf/wavy and frilled leaves) were the best among the loose leaf types, obtaining good yield. 'Lucy Brown' stood out among the crisphead types.
- Published
- 2000
14. Evaluation of cabbage cultivars and hybrids in the state of Acre
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Lédo,Francisco J. da S., Sousa,João A. de, and Silva,Marcos R. da
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hybrids ,compacidade ,Brassica oleracea var. capitata L ,podridão bacteriana ,compactness ,bacterial rot ,híbridos - Abstract
O objetivo do trabalho foi avaliar a produtividade e a qualidade de duas cultivares de polinização aberta (Louco de Verão e União) e nove cvs. híbridas de repolho (Caribe, Fuyutoyo, Kenzan, Master AG-325, Matsukaze, Rookie, Saikô, Sooshu e YR Park), na época seca. O ensaio foi realizado no campo experimental da Embrapa Acre, em Rio Branco-AC, no período de junho a outubro de 1996, em um solo do tipo Argissolo Vermelho-Escuro, textura argilosa. As parcelas foram compostas de duas fileiras de dez plantas, espaçadas de 0,80 m entre elas e de 0,40 m entre plantas. O delineamento experimental foi o de blocos casualizados, com três repetições. Foram avaliadas a produção total e o peso médio das cabeças, índice de formato, relação C/D (comprimento do coração/diâmetro longitudinal), compacidade da cabeça, ciclo de colheita e porcentagem de cabeças apresentando podridão bacteriana. Os híbridos Saikô, Fuyutoyo, Sooshu e YR Park apresentaram as maiores produções total de cabeças (41,8, 41,3, 39,3 e 38,7 t/ha, respectivamente), enquanto 'Louco de Verão', 'Fuyutoyo', 'Saikô', 'Sooshu', 'Master AG-325', 'Caribe' e 'YR Park' resultaram em maiores pesos médios de cabeças, com médias variando de 1410 a 1632 g. Os híbridos YR Park e Sooshu apresentaram cabeças achatadas e os demais, levemente achatadas, com índice de formato variando de 0,90 a 0,77. Para a relação C/D, os híbridos Master AG-325, Sooshu, Rookie, Saikô e Fuyutoyo, e a cv. União tiveram os menores valores, variando de 0,48 a 0,57. Com relação à compacidade da cabeça, com exceção do híbrido YR Park, todos os demais tiveram boa compacidade. Os híbridos Sooshu e YR Park apresentaram ciclo de produção mais precoce, com o inicio da colheita aos 63 dias após o transplantio, e 'Rookie', o mais tardio (91 dias). Os híbridos Saikô e Sooshu destacaram-se dos demais, apresentando cabeças com peso, formato, uniformidade, relação C/D e compacidade adequados para a comercialização, sendo considerados promissores para cultivo na época seca em Rio Branco-AC. The objective of this work was to evaluate yield and quality of two cultivars (Louco de Verão e União) and nine cabbage hybrids (Caribe, Fuyutoyo, Kenzan, Master AG-325, Matsukaze, Rookie, Saikô, Sooshu and YR Park), during the dry season. The experiment was carried out at the experimental field of Embrapa Acre, in Rio Branco, Brazil, from June to October 1996, in a dark-red claysoil soil, of clay texture. Each experimental plot was made up of two lines of ten plants, distanced 0.8 m from each other and 0.4 m between plants. The experimental design was of randomized complete blocks, with three repetitions. The total yield and average head weight, format index, C/D ratio (core lenght/longitudinal diameter), head compactness, harvest cycle and percentage of heads presenting bacterial rot were evaluated. The hybrids Saikô, Fuyutoyo, Sooshu and YR Park presented the greatest total production of heads (41.8, 41.3, 39.3 and 38.7 t/ha, respectively), while 'Louco de Verão', 'Fuyutoyo', 'Saikô', 'Sooshu', 'Master', 'Caribe' and 'YR Park' had the greatest average weight per heads, with averages varying from 1,410 to 1,632 g. The hybrids YR Park and Sooshu presented flat heads and the others slightly flat heads, with format index varying from 0.90 to 0.77. For the C/D ratio, Master AG-325, Sooshu, Rookie, Saikô and Fuyutoyo hybrids and União cultivar had the smallest values, varying from 0.48 to 0.57. In relation to the head compactness, with the exception of YR Park hybrid, all the others showed good compactness. Sooshu and YR Park hybrids presented the most precocious production cycles, with harvest beginning 63 days after transplanting, and 'Rookie' the latest (91 days). Saikô and Sooshu hybrids stood out from the others, presenting heads with uniformity of weight and format, C/D ratio and compactness appropriate for marketing. They were considered promising for cultivation in the dry season, in Rio Branco.
- Published
- 2000
15. An architecture of BDI agent for autonomous locomotives controller
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da Silva, Marcos R., primary, Borges, Andre P., additional, Dordal, Osmar B., additional, Sato, Denise M. V., additional, Avila, Braulio C., additional, Enembreck, Fabricio, additional, and Scalabrin, Edson E., additional
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- 2012
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16. Effect of one month ketoconazole treatment on GH, cortisol and ACTH release after ghrelin, GHRP-6 and GHRH administration in patients with cushing’s disease
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Correa-Silva, Silvia R., primary, Nascif, Sérgio O., additional, Silva, Marcos R., additional, Molica, Patrícia, additional, and Lengyel, Ana-Maria J., additional
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- 2007
- Full Text
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17. Uso da teoria de números índices para adequação de semeadoras-adubadoras de precisão
- Author
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Silva, Marcos R. da, primary, Daniel, Luiz A., additional, and Peche Filho, Afonso, additional
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- 2007
- Full Text
- View/download PDF
18. Bioinformatics, the Clearing-House Mechanism and the Convention on Biological Diversity
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Silva, Marcos R., primary
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- 2004
- Full Text
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19. Desempenho de cultivares de alface no Estado do Acre
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Lédo, Francisco J. da S., primary, Sousa, João A. de, additional, and Silva, Marcos R. da, additional
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- 2000
- Full Text
- View/download PDF
20. Avaliação de cultivares e híbridos de repolho no Estado do Acre
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Lédo, Francisco J. da S., primary, Sousa, João A. de, additional, and Silva, Marcos R. da, additional
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- 2000
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- View/download PDF
21. Evaluation of tumor growth remission in a murine model for subcutaneous solid tumors – Benefits of associating the antitumor agent crotamine with mesoporous nanosilica particles to achieve improved dosing frequency and efficacy.
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Oyadomari, William Yoshio, Anthero, Gabriel Lessa, Silva, Marcos R. de A., Porta, Lucas C., Oliveira, Vitor, Reid, Paul F., Sant'Anna, Osvaldo A., Alves, Wendel A., Nani, João V., and Hayashi, Mirian Akemi Furuie
- Subjects
- *
TUMOR growth , *POISONS , *ANTINEOPLASTIC agents , *ORAL drug administration , *ZETA potential , *MESOPOROUS silica - Abstract
[Display omitted] Crotamine is a highly cationic polypeptide first isolated from South American rattlesnake venom, which exhibits affinity for acidic lysosomal vesicles and proliferating cells. This cationic nature is pivotal for its in vitro cytotoxicity and in vivo anticancer actions. This study aimed to enhance the antitumor efficacy of crotamine by associating it with the mesoporous SBA-15 silica, known for its controlled release of various chemical agents, including large proteins. This association aimed to mitigate the toxic effects while amplifying the pharmacological potency of several compounds. Comprehensive characterization, including transmission electron microscopy (TEM), dynamic light scattering (DLS), and zeta potential analysis, confirmed the successful association of crotamine with the non-toxic SBA-15 nanoparticles. The TEM imaging revealed nanoparticles with a nearly spherical shape and variations in uniformity upon crotamine association. Furthermore, DLS showed a narrow unimodal size distribution, emphasizing the formation of small aggregates. Zeta potential measurements indicated a distinct shift from negative to positive values upon crotamine association, underscoring its effective adsorption onto SBA-15. Intraperitoneal or oral administration of crotamine:SBA-15 in a murine melanoma model suggested the potential to reduce the frequency of crotamine doses without compromising efficacy. Interestingly, while the oral route enhanced the antitumor efficacy of crotamine, pH-dependent release from SBA-15 was observed. Thus, associating crotamine with SBA-15 could reduce the overall required dose to inhibit solid tumor growth, bolstering the prospect of crotamine as a potent anticancer agent. [ABSTRACT FROM AUTHOR]
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- 2023
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22. Impact of percentage and particle size of sugarcane biochar on the sorption behavior of clomazone in Red Latosol.
- Author
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Silva MRFD, Queiroz MELR, Neves AA, Silva AAD, Oliveira AF, Oliveira RL, and Azevedo MM
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- Adsorption, Herbicides metabolism, Isoxazoles metabolism, Oxazolidinones metabolism, Particle Size, Saccharum metabolism, Charcoal metabolism, Herbicides chemistry, Isoxazoles chemistry, Oxazolidinones chemistry, Saccharum drug effects, Soil chemistry
- Abstract
Biochar is a carbonaceous material that has excellent potential as a fertilizer and soil conditioner. However, there is a lack of information concerning the effects of the amount and particle size of this pyrogenic material on the soil sorption capacity. In this work, evaluation was made of changes in clomazone (CMZ) sorption in a Red Latosol following soil conditioning using different percentages (0.25, 0.5, and 1% w/w) of sugarcane biochar in three particle sizes (<106, 106-508, and 508-610 µm). The conditioned soils presented apparent sorption coefficients (Kd) up to 1300 times higher than that of pure soil, besides changes in the behavior of CMZ sorption. The biochar particle size and percentage influenced sorption of the herbicide as well as its retention in the amended soil during desorption processes. Both sorption and desorption Freundlich constants were linearly correlated with the external surface area of the biochar present in the soil.
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- 2018
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23. Liquid chromatographic determination of norfloxacin in extended-release tablets.
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Oliveira PR, Bernardi LS, Mendes C, Cardoso SG, Sangoi MA, and Silva MR
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- Chromatography, Reverse-Phase instrumentation, Chromatography, Reverse-Phase methods, Norfloxacin analysis, Tablets, Enteric-Coated analysis
- Abstract
A stability indicating reversed-phase liquid chromatography method is developed and validated for the determination of norfloxacin in a new formulation of extended-release tablets. The LC method is carried out on a Luna C(18) column (150 x 4.6 mm) maintained at 40 degrees C. The mobile phase is composed of phosphate buffer (0.04 M, pH 3.0)-acetonitrile (84:16, v/v) run at a flow rate of 1.0 mL/min and detection at 272 nm. The chromatographic separation was obtained within 10 min, and it is linear in the concentration range of 0.05-5 microg/mL. Validation parameters, such as the specificity, linearity, precision, accuracy, and robustness, were evaluated, and results were within the acceptable range. Moreover, the proposed method was successfully applied for the assay of norfloxacin in the developed formulations.
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- 2009
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