28 results on '"Silva, M.N."'
Search Results
2. The use of Bagassa guianensis aubl. forestry waste as an alternative for obtaining bioproducts and bioactive compounds
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Pinheiro, W.B.S., Pinheiro Neto, J.R., Botelho, A.S., Dos Santos, K.I.P., Da Silva, G.A., Muribeca, A.J.B., Pamplona, S.G.S.R., Fonseca, S.S.S., Silva, M.N., and Arruda, M.S.P.
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- 2022
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3. Investigation of genetic susceptibility to Mycobacterium tuberculosis (VDR and IL10 genes) in a population with a high level of substructure in the Brazilian Amazon region
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Silva, C.A., Fernandes, D.C.R.O., Braga, A.C.O., Cavalcante, G.C., Sortica, V.A., Hutz, M.H., Leal, D.F.V.B., Fernades, M.R., Santana-da-Silva, M.N., Lopes Valente, S.E., Pastana, L.F., Pinto, P.D.C., Costa, G.E., Ribeiro-dos-Santos, A., Santos, S., and Santos, N.P.C.
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- 2020
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4. How European Fans in Training (EuroFIT), a lifestyle change program for men delivered in football clubs, achieved its effect: a mixed methods process evaluation embedded in a randomised controlled trial.
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Bunn, C., Palmer, V., Chng, N.R., Andersen, E., Gray, C.M., Hunt, K., Jelsma, J.G., Morgan, H., Nijhuis-van der Sanden, M.W.G., Pereira, H.V., Philpott, M., Roberts, G.C., Rooksby, J., Røynesdal, Ø.B., Silva, M.N., Sørensen, M., Teixeira, P.J., Achterberg, T. van, Glind, I. van de, Mechelen, W. van, Nassau, F. van, Ploeg, H.P. van der, Wyke, S., Bunn, C., Palmer, V., Chng, N.R., Andersen, E., Gray, C.M., Hunt, K., Jelsma, J.G., Morgan, H., Nijhuis-van der Sanden, M.W.G., Pereira, H.V., Philpott, M., Roberts, G.C., Rooksby, J., Røynesdal, Ø.B., Silva, M.N., Sørensen, M., Teixeira, P.J., Achterberg, T. van, Glind, I. van de, Mechelen, W. van, Nassau, F. van, Ploeg, H.P. van der, and Wyke, S.
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Item does not contain fulltext, BACKGROUND: A randomised trial of European Fans in Training (EuroFIT), a 12-week healthy lifestyle program delivered in 15 professional football clubs in the Netherlands, Norway, Portugal, and the United Kingdom, successfully increased physical activity and improved diet but did not reduce sedentary time. To guide future implementation, this paper investigates how those effects were achieved. We ask: 1) how was EuroFIT implemented? 2) what were the processes through which outcomes were achieved? METHODS: We analysed qualitative data implementation notes, observations of 29 of 180 weekly EuroFIT deliveries, semi-structured interviews with 16 coaches and 15 club representatives, and 30 focus group discussions with participants (15 post-program and 15 after 12 months). We descriptively analysed quantitative data on recruitment, attendance at sessions and logs of use of the technologies and survey data on the views of participants at baseline, post program and after 12 months. We used a triangulation protocol to investigate agreement between data from difference sources, organised around meeting 15 objectives within the two research questions. RESULTS: We successfully recruited clubs, coaches and men to EuroFIT though the draw of the football club seemed stronger in the UK and Portugal. Advertising that emphasized getting fitter, club-based deliveries, and not 'standing out' worked and attendance and fidelity were good, so that coaches in all countries were able to deliver EuroFIT flexibly as intended. Coaches in all 15 clubs facilitated the use of behaviour change techniques and interaction between men, which together enhanced motivation. Participants found it harder to change sedentary time than physical activity and diet. Fitting changes into daily routines, planning for setbacks and recognising the personal benefit of behaviour change were important to maintain changes. Bespoke technologies were valued, but technological hitches frustrated participants. CONCLUSION
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- 2023
5. Factors influencing the implementation of the EuroFIT lifestyle change program in professional football clubs in Europe: a qualitative study in four European countries
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Nassau, F. van, Huis, A., Glind, I. van de, Andersen, E., Bunn, C., Gray, C.M., Hunt, K., Jelsma, J.G.M., Mechelen, W. van, Morgan, H., Røynesdal, Ø., Pereira, H.V., Ploeg, H.P. van der, Roberts, G.C., Silva, M.N., Sørensen, M., Wyke, S., Nijhuis-van der Sanden, M.W.G., Achterberg, T. van, Nassau, F. van, Huis, A., Glind, I. van de, Andersen, E., Bunn, C., Gray, C.M., Hunt, K., Jelsma, J.G.M., Mechelen, W. van, Morgan, H., Røynesdal, Ø., Pereira, H.V., Ploeg, H.P. van der, Roberts, G.C., Silva, M.N., Sørensen, M., Wyke, S., Nijhuis-van der Sanden, M.W.G., and Achterberg, T. van
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Contains fulltext : 295023.pdf (Publisher’s version ) (Open Access), This paper investigated facilitators and barriers to implementing the European Football Fans in Training program (EuroFIT) in professional sports clubs in England, the Netherlands, Norway, and Portugal. We analyzed qualitative data collected at clubs that delivered EuroFIT, based on semi-structured interviews with coordinating staff (n = 15), coaches (n = 16), and focus group interviews with participants (n = 108), as well as data from clubs that considered delivering EuroFIT in the future, based on interviews with staff (n = 7) and stakeholders (n = 8). Facilitators for implementation related to the content and structure of the program, its evidence-base, and the context for delivery in the football stadia. Financial and human resources were both facilitators and barriers. Further barriers were mostly practical, relating to human resources and infrastructure. Major differences between countries related to experience and commitment to running community projects, and differences in infrastructure, financing, and human resources. Professional football clubs' ability to support health promotion efforts depended on their ethos and the financial and human resources available to them. Overall, the EuroFIT program was well received by clubs, coaches, participants, and stakeholders, which was reflected by the many facilitators supporting sustained implementation. For sustainable implementation, it is crucial that clubs and their stakeholders engage fully with the EuroFIT program and understand that for an adequate program delivery their views (ethos) and ways of working influence the implementation and thereby the effectiveness of EuroFIT. An important prerequisite for future roll out of EuroFIT would be a strong EuroFIT delivery partner organization to ensure financial and human resources while overseeing and guiding the quality of delivery in clubs. The European Football Fans in Training program (EuroFIT) led to health improvements in male football fans delivered through
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- 2023
6. Prostate cancer: Promising biomarkers related to aggressive disease
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Ribeiro da Silva, M.N., Tobias-Machado, M., Lima Pompeo, A.C., Reis, L.O., and da Silva Pinhal, M.A.
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- 2012
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7. Cáncer de próstata: biomarcadores prometedores relacionados con la enfermedad agresiva
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Ribeiro da Silva, M.N., Tobias-Machado, M., Lima-Pompeo, A.C., Reis, L.O., and da Silva Pinhal, M.A.
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- 2012
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8. Ion fluxes and hematological parameters of two teleosts from the Rio Negro, Amazon, exposed to hypoxia/Fluxos ionicos e parametros hematologicos em duas especies de teleosteos do Rio Negro, Amazonia, expostos a hipoxia
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Baldisserotto, B., Chippari-Gomes, A.R., Lopes, N.P., Bicudo, J.E.P.W., Paula-Silva, M.N., Almeida-Val, V.M.F., and Val, A.L.
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- 2008
9. The effect of a programme to improve men's sedentary time and physical activity: The European Fans in Training (EuroFIT) randomised controlled trial
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Wyke, S., Bunn, C., Andersen, E., Silva, M.N., Nassau, F. van, McSkimming, P., Kolovos, S., Gill, J.M., Gray, C.M., Hunt, K., Anderson, A.S., Bosmans, J., Jelsma, J.G., Kean, S., Lemyre, N., Loudon, D.W., Macaulay, L., Maxwell, D.J., McConnachie, A., Mutrie, N., Nijhuis-van der Sanden, M.W.G., Pereira, H.V., Philpott, M., Roberts, G.C., Rooksby, J., Roynesdal, O.B., Sattar, N., Sorensen, M., Teixeira, P.J., Treweek, S., Achterberg, T. van, Glind, I.M. van de, Mechelen, W. van, Ploeg, H.P. van der, Wyke, S., Bunn, C., Andersen, E., Silva, M.N., Nassau, F. van, McSkimming, P., Kolovos, S., Gill, J.M., Gray, C.M., Hunt, K., Anderson, A.S., Bosmans, J., Jelsma, J.G., Kean, S., Lemyre, N., Loudon, D.W., Macaulay, L., Maxwell, D.J., McConnachie, A., Mutrie, N., Nijhuis-van der Sanden, M.W.G., Pereira, H.V., Philpott, M., Roberts, G.C., Rooksby, J., Roynesdal, O.B., Sattar, N., Sorensen, M., Teixeira, P.J., Treweek, S., Achterberg, T. van, Glind, I.M. van de, Mechelen, W. van, and Ploeg, H.P. van der
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Contains fulltext : 202275.pdf (publisher's version ) (Open Access), BACKGROUND: Reducing sitting time as well as increasing physical activity in inactive people is beneficial for their health. This paper investigates the effectiveness of the European Fans in Training (EuroFIT) programme to improve physical activity and sedentary time in male football fans, delivered through the professional football setting. METHODS AND FINDINGS: A total of 1,113 men aged 30-65 with self-reported body mass index (BMI) >/=27 kg/m2 took part in a randomised controlled trial in 15 professional football clubs in England, the Netherlands, Norway, and Portugal. Recruitment was between September 19, 2015, and February 2, 2016. Participants consented to study procedures and provided usable activity monitor baseline data. They were randomised, stratified by club, to either the EuroFIT intervention or a 12-month waiting list comparison group. Follow-up measurement was post-programme and 12 months after baseline. EuroFIT is a 12-week, group-based programme delivered by coaches in football club stadia in 12 weekly 90-minute sessions. Weekly sessions aimed to improve physical activity, sedentary time, and diet and maintain changes long term. A pocket-worn device (SitFIT) allowed self-monitoring of sedentary time and daily steps, and a game-based app (MatchFIT) encouraged between-session social support. Primary outcome (objectively measured sedentary time and physical activity) measurements were obtained for 83% and 85% of intervention and comparison participants. Intention-to-treat analyses showed a baseline-adjusted mean difference in sedentary time at 12 months of -1.6 minutes/day (97.5% confidence interval [CI], -14.3-11.0; p = 0.77) and in step counts of 678 steps/day (97.5% CI, 309-1.048; p < 0.001) in favor of the intervention. There were significant improvements in diet, weight, well-being, self-esteem, vitality, and biomarkers of cardiometabolic health in favor of the intervention group, but not in quality of life. There was a 0.95 probability of EuroFIT
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- 2019
10. Scaling effects on hypoxia tolerance in the Amazon fish Astronotus ocellatus (Perciformes: Cichlidae): contribution of tissue enzyme levels
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Almeida-Val, V.M.F, Val, A.L, Duncan, W.P, Souza, F.C.A, Paula-Silva, M.N, and Land, S
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- 2000
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11. Study protocol of European Fans in Training (EuroFIT): a four-country randomised controlled trial of a lifestyle program for men delivered in elite football clubs
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Nassau, F. van, Ploeg, H.P. van der, Abrahamsen, F., Andersen, E., Anderson, A.S., Bosmans, J.E., Bunn, C., Chalmers, M., Clissmann, C., Gill, J.M., Gray, C.M., Hunt, K., Jelsma, J.G., Guardia, J.G. La, Lemyre, P.N., Loudon, D.W., Macaulay, L., Maxwell, D.J., McConnachie, A., Martin, A., Mourselas, N., Mutrie, N., Nijhuis-van der Sanden, M.W.G., O'Brien, K., Pereira, H.V., Philpott, M., Roberts, G.C., Rooksby, J., Rost, M., Roynesdal, O., Sattar, N., Silva, M.N., Sorensen, M., Teixeira, P.J., Treweek, S., Achterberg, T. van, Glind, I. van de, Mechelen, W. van, Wyke, S., Nassau, F. van, Ploeg, H.P. van der, Abrahamsen, F., Andersen, E., Anderson, A.S., Bosmans, J.E., Bunn, C., Chalmers, M., Clissmann, C., Gill, J.M., Gray, C.M., Hunt, K., Jelsma, J.G., Guardia, J.G. La, Lemyre, P.N., Loudon, D.W., Macaulay, L., Maxwell, D.J., McConnachie, A., Martin, A., Mourselas, N., Mutrie, N., Nijhuis-van der Sanden, M.W.G., O'Brien, K., Pereira, H.V., Philpott, M., Roberts, G.C., Rooksby, J., Rost, M., Roynesdal, O., Sattar, N., Silva, M.N., Sorensen, M., Teixeira, P.J., Treweek, S., Achterberg, T. van, Glind, I. van de, Mechelen, W. van, and Wyke, S.
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Contains fulltext : 171556.pdf (publisher's version ) (Open Access), BACKGROUND: Lifestyle interventions targeting physical activity, sedentary time and dietary behaviours have the potential to initiate and support behavioural change and result in public health gain. Although men have often been reluctant to engage in such lifestyle programs, many are at high risk of several chronic conditions. We have developed an evidence and theory-based, gender sensitised, health and lifestyle program (European Fans in Training (EuroFIT)), which is designed to attract men through the loyalty they feel to the football club they support. This paper describes the study protocol to evaluate the effectiveness and cost-effectiveness of the EuroFIT program in supporting men to improve their level of physical activity and reduce sedentary behaviour over 12 months. METHODS: The EuroFIT study is a pragmatic, two-arm, randomised controlled trial conducted in 15 football clubs in the Netherlands, Norway, Portugal and the UK (England). One-thousand men, aged 30 to 65 years, with a self-reported Body Mass Index (BMI) >/=27 kg/m(2) will be recruited and individually randomised. The primary outcomes are objectively-assessed changes in total physical activity (steps per day) and total sedentary time (minutes per day) at 12 months after baseline assessment. Secondary outcomes are weight, BMI, waist circumference, resting systolic and diastolic blood pressure, cardio-metabolic blood biomarkers, food intake, self-reported physical activity and sedentary time, wellbeing, self-esteem, vitality and quality of life. Cost-effectiveness will be assessed and a process evaluation conducted. The EuroFIT program will be delivered over 12 weekly, 90-minute sessions that combine classroom discussion with graded physical activity in the setting of the football club. Classroom sessions provide participants with a toolbox of behaviour change techniques to initiate and sustain long-term lifestyle changes. The coaches will receive two days of training to enable them to create a posi
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- 2016
12. Nanotecnología y nanomedicina: un nuevo horizonte para el diagnóstico y tratamiento médico
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De Silva, M.N.
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- 2007
13. Permanent Genetic Resources added to Molecular Ecology Resources Database 1 October 2012-30 November 2012
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Aksoy, S., Almeida-Val, V.M.F., Azevedo, V.C.R., Baucom, R., Bazaga, P., Beheregaray, L.B., Bennetzen, J.L., Brassaloti, R.A., Burgess, T.I., Caccone, A., Chang, S-M, Ciampi, A.Y., Ciancaleoni, S., Clímaco, G.T., Clouet, C., Coimbra, M.R.M., Coutinho, L.L., Dantas, H.L., De Vega, C., Echodu, R., Enyaru, J., Figueira, A., Filho, M.A.G., Foltz, B., Fressigné, L., Gadomski, M., Gauthier, N., Herrera, C.M., Hyseni, C., Jorge, E.C., Kaczmarczyk, D., Knott, E., Kuester, A., Lima, A.P.S., Lima, M.A., Lima, M.P., Longo, A.L.B., Lor, G., Maggioni, R., Marques, T.S., Martins, A.R., Matoso, D.A., Medrano, M., Mendonça, M.A.C., Mettler, R., Nascimento, P.R.M., Negri, V., Oliveira, K.K.C., Oliveira, L. O., Ovcarenko, I., Paula-Silva, M.N., Raggi, L., Sandoval-Castillo, J., Santos, C.H.A., Martin Schaefer, H., Segelbacher, G., Seino, M.M., Sistrom, M., Taole, M.M., Teske, P.R., Tsagkarakou, A., Verdade, L.M., Villela, P.M.S., Vinson, C.C., Wingfield, B.D., Wingfield, M.J., Aksoy, S., Almeida-Val, V.M.F., Azevedo, V.C.R., Baucom, R., Bazaga, P., Beheregaray, L.B., Bennetzen, J.L., Brassaloti, R.A., Burgess, T.I., Caccone, A., Chang, S-M, Ciampi, A.Y., Ciancaleoni, S., Clímaco, G.T., Clouet, C., Coimbra, M.R.M., Coutinho, L.L., Dantas, H.L., De Vega, C., Echodu, R., Enyaru, J., Figueira, A., Filho, M.A.G., Foltz, B., Fressigné, L., Gadomski, M., Gauthier, N., Herrera, C.M., Hyseni, C., Jorge, E.C., Kaczmarczyk, D., Knott, E., Kuester, A., Lima, A.P.S., Lima, M.A., Lima, M.P., Longo, A.L.B., Lor, G., Maggioni, R., Marques, T.S., Martins, A.R., Matoso, D.A., Medrano, M., Mendonça, M.A.C., Mettler, R., Nascimento, P.R.M., Negri, V., Oliveira, K.K.C., Oliveira, L. O., Ovcarenko, I., Paula-Silva, M.N., Raggi, L., Sandoval-Castillo, J., Santos, C.H.A., Martin Schaefer, H., Segelbacher, G., Seino, M.M., Sistrom, M., Taole, M.M., Teske, P.R., Tsagkarakou, A., Verdade, L.M., Villela, P.M.S., Vinson, C.C., Wingfield, B.D., and Wingfield, M.J.
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This article documents the addition of 153 microsatellite marker loci to the Molecular Ecology Resources Database. Loci were developed for the following species: Brassica oleracea, Brycon amazonicus, Dimorphandra wilsonii, Eupallasella percnurus, Helleborus foetidus, Ipomoea purpurea, Phrynops geoffroanus, Prochilodus argenteus, Pyura sp., Sylvia atricapilla, Teratosphaeria suttonii, Trialeurodes vaporariorum and Trypanosoma brucei. These loci were cross-tested on the following species: Dimorphandra coccicinea, Dimorphandra cuprea, Dimorphandra gardneriana, Dimorphandra jorgei, Dimorphandra macrostachya, Dimorphandra mollis, Dimorphandra parviflora and Dimorphandra pennigera.
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- 2013
14. Ectopia ureteral unilateral congênita em uma cadela Teckel Dachshund com pelagem arlequim: relato de caso
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Silva, M.N., primary, Larangeira, D.F., additional, Penha, E.M., additional, Oriá, A.P., additional, Costa Neto, J.M., additional, and Barrouin-Melo, S.M., additional
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- 2012
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15. Identification of genes encoding hypothetical proteins in open-reading frame expressed sequence tags from mammalian stages of Trypanosoma cruzi
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Martins, C., primary, Reis-Cunha, J.L., additional, Silva, M.N., additional, Pereira, E.G., additional, Pappas Jr., G.J., additional, Bartholomeu, D.C., additional, and Zingales, B., additional
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- 2011
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16. Nanotecnología y nanomedicina: un nuevo horizonte para el diagnóstico y tratamiento médico
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De Silva, M.N., primary
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- 2007
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17. A case of giant pleomorphic adenoma of the parotid gland
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de Silva, M.N, primary, Kosgoda, K.M.S, additional, Tilakaratne, W.M, additional, and Murugadas, P, additional
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- 2004
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18. A microtool for in vitro cell array manipulation.
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Baldi, A., Fass, J.N., De Silva, M.N., Odde, D.J., and Ziaie, B.
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- 2002
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19. Specialized metabolism and biochemical suppression during aestivation of the extant South American lungfish — Lepidosiren paradoxa
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Almeida-Val, V.M.F, primary, Mesquita-Saad, L.S.B, additional, Leitão, M.A.B, additional, Paula-Silva, M.N, additional, and Chippari-Gomes, A.R, additional
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- 2000
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20. Morphology of the male genital system of the Bushy-Tailed opossum Glironia venusta Thomas, 1912 (Didelphimorphia, Didelphidae)
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NOGUEIRA, J.C., primary, FERREIRA DA SILVA, M.N., additional, and CÂMARA, B.G.O., additional
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- 1999
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21. No Co-Expression of LDH-C In Amazon Cichlids
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Farias, I.P, primary, Paula-Silva, M.N, additional, and Almeida-Val, V.M.F, additional
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- 1997
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22. Unusual cranial nerve palsy caused by cavernous sinus aneurysms - a brief review
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Silva, M.N., Saeki, N., Hirai, S., and Yamaura, A.
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- 1999
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23. A microtool for in vitro cell array manipulation
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Baldi, A., primary, Fass, J.N., additional, De Silva, M.N., additional, Odde, D.J., additional, and Ziaie, B., additional
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24. Simultaneous neurite elicitation and elongation from neurons using a microfabricated post array
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De Silva, M.N., primary, Baldi, A., additional, Fass, J.N., additional, Ziaie, B., additional, and Odde, D.J., additional
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25. Enhancing learning for Visually Impaired with technology: MATHVIS.
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Soysa, L., Lokuge, K., Wimalasundera, I., and De Silva, M.N.
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- 2010
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26. Characterization of carbon deposits during heterogeneous catalysis using terahertz time-domain spectroscopy.
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de-Silva, M.N., McElroy, C.T., McGregor, J., York, A.P.E., Zeitler, J.A., and Gladden, L.F.
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- 2010
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27. Abstracts
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Barthelemy, O., Silvain, J., Brieger, D., Bellemain-Appaix, A., Cayla, G., Beygui, F., Lancar, R., Collet, J.P., Mercadier, A., Montalescot, G., Cha, K.S., Nam, Y.H., Kim, J.H., Park, S.Y., Park, T.H., Kim, M.H., Kim, Y.D., Lee, H.C., Ahn, M.S., Hong, T.J., Blanco, R., Blanco, F., Szarfer, J., Garcia Escudero, A., Gigena, G., Gagliardi, J., Rodriguez, A., Sarmiento, R., Affatatto, S., Riccitelli, M., Petris, A., Datcu, M.D., Pop, C., Radoi, M., Arsenescu-Georgescu, C., Petrescu, I., Petrescu, L., Serban, L., Nechita, E., Tatu-Chitoiu, G., Tatu-Chitoiu, G., Dorobantu, M., Benedek, I., Craiu, E., Sinescu, C., Ionescu, D.D., Radoi, M., Pop, C., Ginghina, C., Minescu, B., Izzo, A., Mantovani, P., Tomasi, L., Dalloglio, L., Bonatti, S., Rosiello, R., Romano, M., Agostini, F., Zanini, R., Zhao, Z.Y., Wu, Y.J., Li, J.J., Yany, Y.J., Qian, H.Y., Tang, Y.D., Timoteo, A.T., Toste, A., Lousinha, A., Ramos, R., Oliveira, J.A., Ferreira, M.L., Ferreira, R.C., Cabades, C., Diez Gil, J.L., Aguar, P., Sanmiguel, D., Lopez-March, A., Marmol, R., Guerra, L., Girbes, V., Ferrando, J., Rincon De Arellano, A., Timoteo, A.T., Ramos, R., Toste, A., Oliveira, J.A., Patricio, L., Ferreira, M.L., Ferreira, R.C., Blondal, M., Ainla, T., Marandi, T., Eha, J., Timoteo, A.T., Oliveira, M.M., Silva, M.N., Cunha, P.S., Feliciano, J., Silva, S., Ferreira, R.C., Kanovsky, J., Kala, P., Parenica, J., Poloczek, M., Prymusova, K., Kubkova, L., Spinar, J., Olinic, D., Homorodean, C., Ober, M., Olinic, M., Andrioaia, C., Condac, A., Masmoudi, M., Berdaoui, B., Labidi, S., Tapia Ballesteros, C., Hernandez Luis, C., Sandin, M.G., Vegas, J.M., Andion, R., Martinez, N., Gonzalez, I.A., Alvarado, M., Amat, I.J., San Roman, J.A., Garcia Gonzalez, M.J., Arroyo Ucar, E., Hernandez Garcia, C., Dorta Martin, M., Marrero Rodriguez, F., Dragu, R., Kapeliovich, M., Hammerman, H., Silva, D., Cortez-Dias, N., Jorge, C., Silva Marques, J., Carilho Ferreira, P., Robalo Martins, S., Almeida Ribeiro, M., Calisto, C., Fiuza, M., Lopes, M.G., Milicevic, P., Panic, M., Stankovic, I., Milicevic, D., Kalezic, T., Kafedzic, S., Ilic, I., Cerovic, M., Putnikovic, B., Neskovic, A., Rott, D., Leibowitz, D., Monhart, Z., Reissigova, J., Grunfeldova, H., Jansky, P., Timoteo, A.T., Valente, B., Oliveira, J.A., Ferreira, M.L., Ferreira, R.C., Villanueva Benito, I., Solla, I., Paredes, E., Diaz Castro, O., Calvo, F., Baz, J.A., Iniguez, A., Aleksova, A., Gerloni, R., Belfiore, R., Carriere, C., Barbati, G., Fabris, E., Possa, F., Nait, D., Milo, M., Sinagra, G., Marques, N., Mimoso, J., Gomes, V., Agra Bermejo, R.M., Emad Abu Assi, E.A.A., Sergio Raposeiras Roubin, S.R.R., Pilar Cabanas Grandio, P.C.G., Carlos Pena Gil, C.P.G., Jose Maria Garcia Acuna, J.M.G.A., Jose Ramon Gonzalez Juanatey, J.R.G.J., Daly, M.J., Scott, P., Owens, C.G., Tomlin, A., Smith, B., Adgey, A.A.J., Alvarez-Contreras, L.R., Juarez, U., Altamirano, A., Arias, A., Alvarez-San Gabriel, A., Gonzalez-Pacheco, H., Martinez-Sanchez, C., Rahnavardi, 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- Abstract
Background: Radial access for PCI is increasing but its use in emergency still remains confidential. We report our single center experience where all interventional cardiologists use the radial access as default strategy for primary PCI. Methods and Results: STEMI patients (n = 671) were evaluated for bleeding complications using a web-based registry (e-PARIS). In-hospital bleeding was adjudicated using various definitions (TIMI, GUSTO, STEEPLE). MACE was the composite of death, MI and stroke. In this non-selected, high risk population, 6.1% had cardiogenic shock on admission, 3.9% out-of-hospital cardiac arrest and 51.2% multivessel disease. Radial access (88%) was the default strategy as was abciximab (78%). Clopidogrel loading dose ranged from 300 to 900 mg. Pre-hospital fibrinolysis was used in 7.1%. Hemodynamic support devices (IABP, ECMO, Tandem Heart) were needed in 7.0%. In-hospital bleeding rates varied widely according to the definitions used: 2.5%, 1.5%, 5.7%, 9.2% and 10.9% with TIMI Major, GUSTO Severe, TIMI Major/minor, GUSTO Severe/moderate or STEEPLE Major, respectively. In-hospital death rate was 5.5%. One-year mortality (8.2%) was seriously impacted by in-hospital bleeding (31.6% vs 6.8%, p < 0.001). The most frequent bleeding site was gastro-intestinal (figure). GUSTO Severe/moderate bleeding was independently correlated with MACE (OR 2.60; 95%CI 1.21–5.59; p = 0.01) and radial access was a strong predictor of survival (OR 0.33; 95%CI 0.17–0.56; p = 0.002). Conclusions: The gastro-intestinal tract is the most frequent site of bleeding when the radial artery is the predominant vascular access site for primary PCI. GUSTO Severe/moderate bleeding is an independent predictor of MACE while radial access predicts survival.
- Published
- 2010
- Full Text
- View/download PDF
28. Simultaneous neurite elicitation and elongation from neurons using a microfabricated post array.
- Author
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De Silva, M.N., Baldi, A., Fass, J.N., Ziaie, B., and Odde, D.J.
- Published
- 2002
- Full Text
- View/download PDF
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