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5. RailLink - Enhanced Train Operations System for Sri Lanka Railways.

Author

Silva, K. R. Rasanga, A. J. Y. J., Dilshan, Herath, Achini M., Senadeera, N. A. J. N., De Silva, D. I., and Wijendra, Dinuka R.

Subjects
ARTIFICIAL intelligence, MACHINE learning, DIGITAL learning, TECHNOLOGICAL innovations
Abstract

RailLink, a comprehensive system designed for the Sri Lanka Railway Department, tackles the challenges faced in railway operations through four primary subsystems: the Self Ticketing System and Chatbot, Timetable Management and Passenger Demand Forecasting System, Driver Management System, and Fleet Management System. The Self Ticketing System and Chatbot enhance customer convenience by offering realtime ticket booking and information access through a userfriendly web application, reducing queues and improving satisfaction. The Timetable Management and Passenger Demand Forecasting System optimize resource allocation and train schedules, ensuring efficient resource use and improved passenger convenience through predictive modeling. The Driver Management System enhances safety and operational efficiency by considering driver health, previous journey data, and grades when allocating drivers. The Fleet Management System, using blockchain technology, ensures secure data sharing among subdepartments, safeguarding data integrity and confidentiality for effective fleet management. By harnessing advanced technologies, RailLink promises to modernize railway operations, resulting in increased efficiency, customer satisfaction, revenue, and overall network performance. [ABSTRACT FROM AUTHOR]

Published
2023
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9. A PERCEPÇÃO DE SI E DO OUTRO: UM ESTUDO SOBRE IDENTIDADE E LITERATURA NO CENTRO ESTADUAL DE ENSINO MÉDIO EM TEMPO INTEGRAL MANOEL DUARTE DA CUNHA

Author

SILVA, K. R., BARBOSA, J. L. V., SENATORE, R. C. M., and MORILA, A. P.

Abstract

Made available in DSpace on 2019-06-19T02:07:17Z (GMT). No. of bitstreams: 1 tese_13395_109 - Karina Rodrigues Silva.pdf: 1674425 bytes, checksum: 69a4f33376e806e505f132d6006d1389 (MD5) Previous issue date: 2019-04-09 Este trabalho aborda a percepção dos alunos sobre identidade em uma escola de Ensino Médio em tempo integral, Manoel Duarte da Cunha, localizada no município de Pedro Canário. Assim é elencada a perspectiva do aluno sobre o que ele pensa sobre identidade assim como ele consegue perceber a identidade de personagens da literatura capixaba. Para essa atividade foi solicitado aos alunos que lessem duas obras literárias, Karina de Virgínia Tamanini e Reino não conquistado de Renato Pacheco. Essas obras retratam os tipos de ideais de sujeito que deveriam formar a nação e o estado do Espírito Santo, o negro e o branco imigrante. Para construir esse trabalho foi utilizado como arcabouço teórico as contribuições de Jürgen Habermas, filósofo herdeiro da escola de Frankfurt Habermas aprofunda temas que foram deixados em aberto por esta escola, como a autonomia do ser humano. O autor constrói uma teoria que tem como ponto crucial de seus trabalhos, o agir comunicativo, para ele é em atos performativos que nos socializamos, construímos nossa individualidade e adquirimos nossa identidade, todavia ela não é fixa e está relacionada com a forma que realizamos nossas escolhas, saber quem se é e o que se quer, é um dos pressupostos de ter uma identidade do eu, última fase de uma identidade autônoma desenvolvida, que significa a capacidade de agir de forma imputável. Desta forma o leitor encontrará um trabalho que aborda não a identidade do aluno, pois ela não é palpável, mas é um processo de construção de desenvolvimento e aquisição, estamos aqui discutindo as percepções dos alunos sobre esses caminhos de aquisição da identidade.

Published
2019

12. Teneurin-2 presence in rat and human odontoblasts

Author

Torres-da-Silva, K. R., primary, Tessarin, G. W. L., additional, Dias, C. A., additional, Guiati, I. Z., additional, Ervolino, E., additional, Gonçalves, A., additional, Beneti, I. M., additional, Lovejoy, D. A., additional, and Casatti, C. A., additional

Published
2017
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14. IMUNIDADE INDUZIDA PELA USO COMBINADO DE VACINA ATENUADA (ESTIRPE MASSACHUSETTS) E VACINA INATIVADA EXPERIMENTAL (VARIANTE BR-I) CONTRA O DESAFIO COM ESTIRPE VARIANTE BRASILEIRA DO VÍRUS DA BRONQUITE INFECCIOSA AVIÁRIA

Author

SANTOS, R. M., primary, SILVA, K. R., additional, LOPES, P. D., additional, FERNANDO, F. S., additional, BORZI, M. M., additional, MONTASSIER, M. F. S., additional, OKINO, C. H., additional, and MONTASSIER, H. J., additional

Published
2015
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15. Resíduo De Quartzito - Matéria-Prima Alternativa Para Ser Incorporada em Massas Utilizadas na Produção de Grés Porcelanato.

Author

Silva, K. R., Campos, L. F. A., and Santana, L. N. L.

Abstract

Copyright of Revista Eletrônica de Materiais e Processos is the property of Revista Eletronica de Materiaia e Processos and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2018

16. 'Metodologia para a Estimativa e Espacialização de Variáveis do Balanço Hidríco'

Author

SILVA, K. R., XAVIER, A. C., PEZZOPANE, J. E. M., PEZZOPANE, J. R. M., GARCIA, G. O., and CECILIO, R. A.

Subjects
aptidão climática, Hevea brasiliensis, int, Microcylus ulei
Abstract

Made available in DSpace on 2016-08-29T15:36:52Z (GMT). No. of bitstreams: 1 tese_3749_.pdf: 3354957 bytes, checksum: 5031b639a212ea34971b41b49bae46bb (MD5) Previous issue date: 2010-03-26 O objetivo deste trabalho foi desenvolver um método que produza estimativas e cartas de aptidão climáticas dos elementos do balanço hídrico para a elaboração de um zoneamento edafoclimático para a cultura da seringueira no Estado do Espírito Santo. Foram utilizados dados de 110 estações pluviométricas com período de medição entre os anos de 1977 a 2006. As temperaturas mensais foram espacializadas utilizando-se as equações desenvolvidas por Castro (2008) e dados do modelo digital de elevação GTOPO30. A espacialização da precipitação mensal se procedeu a partir da prévia seleção dos interpoladores espaciais de maior capacidade preditiva por meio da validação cruzada. Mediante os dados de temperatura e precipitação mensal, foi realizado o balanço hídrico de forma pontual para todos os 110 postos meteorológicos. As variáveis do balanço hídrico foram espacializadas a partir da seleção de interpoladores espaciais de maior capacidade preditiva por meio da validação cruzada. Foi desenvolvida uma metodologia de espacialização das variáveis do balanço hídrico, tendo como parâmetros de entrada mapas de temperatura mensal, precipitação mensal e solos com CADs de 90, 210 e 300 mm. O desempenho dos interpoladores espaciais e da metodologia de espacialização das variáveis do balanço hídrico, foi realizada com as 14 estações observadas, possibilitando assim uma comparação entre métodos de espacialização. Baseado nos mapas temáticos de temperatura média anual, temperatura do mês mais frio, deficiência hídrica (obtidos no melhor método de espacialização) e mapa de solos foi feito uma reclassificação de acordo com as exigências climáticas da espécie e em seguida a sobreposição dessas informações, obtendo assim um mapa de zoneamento edafoclimático para a cultura da seringueira. Os resultados mostraram que o interpolador krigagem foi o mais eficientes para a espacialização das precipitações mensais. A metodologia de espacialização proposta apresentou melhores índices estatísticos para as variáveis do balanço hídrico quando comparado com os métodos tradicionais de interpolação, sendo essa metodologia utilizada para a geração do mapa de deficiência hídrica no zoneamento. Maior parte do estado apresenta restrição térmica ao cultivo da seringueira, com condições favoráveis a esporulação do fungo Microcylus ulei.

Published
2010

24. Mice with Deletion of Neuromedin B Receptor Exhibit Decreased Oral Glucose-Stimulated Insulin Release.

Author

Paula, G. S. M., Souza, L. L., Bressane, N. O. S., Maravalhas, R., Wilieman, M., Bento-Bernardes, T., Silva, K. R., Mendonca, L. S., Oliveira, K. J., and Pazos-Moura, C. C.

Subjects
GASTRIN-releasing peptide, BOMBESIN, INCRETINS, LABORATORY mice, BLOOD serum analysis
Abstract

Neuromedin B (NB) and gastrin-releasing peptide (GRP) are bombesin-like peptides, found in the gastrointestinal tube and pancreas, among other tissues. Consistent data proposed that GRP stimulates insulin secretion, acting directly in pancreatic cells or in the release of gastrointestinal hormones that are incretins. However, the role of NB remains unclear. We examined the glucose homeostasis in mice with deletion of NB receptor (NBR-KO). Female NBR-KO exhibited similar fasting basal glucose with lower insulinemia (48.4 %) and lower homeostasis model assessment of insulin resistance index (50.5 %) than wild type (WT). Additionally, they were more tolerant to oral glucose, demonstrated by a decrease in the area under the glucose curve (18 %). In addition, 15 min after an oral glucose load, female and male NBR-KO showed lower insulin serum levels (45.6 and 26.8 %, respectively) than WT, even though blood glucose rose to similar levels in both groups. Single injection of NB, one hour before the oral glucose administration, tended to induce higher serum insulin in WT (28.9 %, p = 0.3), however the same did not occur in NBR-KO. They showed no changes in fasting insulin content in pancreatic islets by immunohistochemistry, however, the fasting serum levels of glucagon-like peptide, a potent incretin, exhibited a strong trend to reduction (40 %, p = 0.07). Collectively, mice with deletion of NB receptor have lower insulinemia, especially in response to oral glucose, and females also exhibited a better glucose tolerance, suggesting the involvement of NB and its receptor in regulation of insulin secretion induced by incretins, and also, in insulin sensitivity. [ABSTRACT FROM AUTHOR]

Published
2016
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26. Poster Session 3

Author

Fabbri, G. M. T., primary, Baldasseroni, S., additional, Panuccio, D., additional, Zoni Berisso, M., additional, Scherillo, M., additional, Lucci, D., additional, Di Pasquale, G., additional, Mathieu, G., additional, Burazor, I., additional, Burazor, M., additional, Perisic, Z., additional, Atanaskovic, V., additional, Erakovic, V., additional, Stojkovic, A., additional, Vogtmann, T., additional, Schoebel, C., additional, Sogorski, S., additional, Sebert, M., additional, Schaarschmidt, J., additional, Fietze, I., additional, Baumann, G., additional, Penzel, T., additional, Mornos, C., additional, Ionac, A., additional, Cozma, D., additional, Dragulescu, D., additional, Mornos, A., additional, Petrescu, L., additional, Pescariu, L., additional, Brembilla-Perrot, B., additional, Khachab, H., additional, Lamberti, F., additional, Bellini, C., additional, Remoli, R., additional, Cogliandro, T., additional, Nardo, R., additional, Bellusci, F., additional, Mazzuca, V., additional, Gaspardone, A., additional, Aguinaga Arrascue, L. E., additional, Bravo, A., additional, Garcia Freire, P., additional, Gallardo, P., additional, Hasbani, E., additional, Quintana, R., additional, Dantur, J., additional, Inoue, K., additional, Ueoka, A., additional, Tsubakimoto, Y., additional, Sakatani, T., additional, Matsuo, A., additional, Fujita, H., additional, Kitamura, M., additional, Wegrzynowska, M., additional, Konduracka, E., additional, Pietrucha, A. Z., additional, Mroczek-Czernecka, D., additional, Paradowski, A., additional, Bzukala, I., additional, Nessler, J., additional, Igawa, O., additional, Adachi, M., additional, Atarashi, H., additional, Kusama, Y., additional, Kodani, E., additional, Okazaki, R., additional, Nakagomi, A., additional, Endoh, Y., additional, Baez-Escudero, J. L., additional, Dave, A. S., additional, Sasaridis, C. M., additional, Valderrabano, M., additional, Tilz, R., additional, Bai, R., additional, Di Biase, L., additional, Gallinghouse, G. J., additional, Gibson, D., additional, Pisapia, A., additional, Wazni, O., additional, Natale, A., additional, Arujuna, A., additional, Karim, R., additional, Rinaldi, A., additional, Cooklin, M., additional, Rhode, K., additional, Razavi, R., additional, O'neill, M., additional, Gill, J., additional, Kusa, S., additional, Komatsu, Y., additional, Kakita, K., additional, Takayama, K., additional, Taniguchi, H., additional, Otomo, K., additional, Iesaka, Y., additional, Ammar, S., additional, Reents, T., additional, Fichtner, S., additional, Wu, J., additional, Zhu, P., additional, Kolb, C., additional, Hessling, G., additional, Deisenhofer, I., additional, Gilbert, G., additional, Mohanty, P., additional, Cunningham, J., additional, Metz, T., additional, Horton, R., additional, Tao, S., additional, Yamauchi, Y., additional, Okada, H., additional, Maeda, S., additional, Obayashi, T., additional, Isobe, M., additional, Chan, J., additional, Johar, S., additional, Wong, T., additional, Markides, V., additional, Hussain, W., additional, Konstantinidou, M., additional, Wissner, E., additional, Fuernkranz, A., additional, Yoshiga, Y., additional, Metzner, A., additional, Kuck, K.- H., additional, Ouyang, F., additional, Kettering, K., additional, Gramley, F., additional, Mollnau, H., additional, Weiss, C., additional, Bardeleben, S., additional, Biasco, L., additional, Scaglione, M., additional, Caponi, D., additional, Di Donna, P., additional, Sergi, D., additional, Cerrato, N., additional, Blandino, A., additional, Gaita, F., additional, Fiala, M., additional, Wichterle, D., additional, Sknouril, L., additional, Bulkova, V., additional, Chovancik, J., additional, Nevralova, R., additional, Pindor, J., additional, Januska, J., additional, Choi, J. I., additional, Ban, J. E., additional, Yasutsugu, N., additional, Park, J. S., additional, Jung, J. S., additional, Lim, H. E., additional, Park, S. W., additional, Kim, Y. H., additional, Kuhne, M., additional, Reichlin, T., additional, Ammann, P., additional, Schaer, B., additional, Osswald, S., additional, Sticherling, C., additional, Ohe, M., additional, Goya, M., additional, Hiroshima, K., additional, Hayashi, K., additional, Makihara, Y., additional, Nagashima, M., additional, Fukunaga, M., additional, An, Y., additional, Dorwarth, U., additional, Schmidt, M., additional, Wankerl, M., additional, Krieg, J., additional, Straube, F., additional, Hoffmann, E., additional, Kathan, S., additional, Defaye, P., additional, Mbaye, A., additional, Cassagneau, R., additional, Gagniere, V., additional, Jacon, P., additional, Pokushalov, E., additional, Romanov, A., additional, Artemenko, S., additional, Shabanov, V., additional, Elesin, D., additional, Stenin, I., additional, Turov, A., additional, Losik, D., additional, Kondo, K., additional, Miake, J., additional, Yano, A., additional, Ogura, K., additional, Kato, M., additional, Shigemasa, C., additional, Sekiguchi, Y., additional, Tada, H., additional, Yoshida, K., additional, Naruse, Y., additional, Yamasaki, H., additional, Igarashi, M., additional, Machino, T., additional, Aonuma, K., additional, Chen, S., additional, Liu, S., additional, Chen, G., additional, Meng, W., additional, Zhang, F., additional, Yan, Y., additional, Sciarra, L., additional, Dottori, S., additional, Lanzillo, C., additional, De Ruvo, E., additional, De Luca, L., additional, Minati, M., additional, Lioy, E., additional, Calo', L., additional, Lin, J., additional, Nie, Z., additional, Zhu, M., additional, Wang, X., additional, Zhao, J., additional, Hu, W., additional, Tao, H., additional, Ge, J., additional, Johansson, B., additional, Houltz, B., additional, Edvardsson, N., additional, Schersten, H., additional, Karlsson, T., additional, Wandt, B., additional, Berglin, E., additional, Hoyt, R. H., additional, Jenson, B. P., additional, Trines, S. A. I. P., additional, Braun, J., additional, Tjon Joek Tjien, A., additional, Zeppenfeld, K., additional, Tavilla, G., additional, Klautz, R. J. M., additional, Schalij, M. J., additional, Krausova, R., additional, Cihak, R., additional, Peichl, P., additional, Kautzner, J., additional, Pirk, J., additional, Skalsky, I., additional, Maly, J., additional, Imai, K., additional, Sueda, T., additional, Orihashi, K., additional, Picarra, B. C., additional, Santos, A. R., additional, Dionisio, P., additional, Semedo, P., additional, Matos, R., additional, Leitao, M., additional, Banha, M., additional, Trinca, M., additional, Elder, D. H. J., additional, George, J., additional, Jain, R., additional, Lang, C. C., additional, Choy, A. M., additional, Konert, M., additional, Loescher, S., additional, Hartmann, A., additional, Aversa, E., additional, Chirife, R., additional, Sztyglic, E., additional, Mazzetti, H., additional, Mascheroni, O., additional, Tentori, M. C., additional, Pop, R. M., additional, Margulescu, A. D., additional, Dulgheru, R., additional, Enescu, O., additional, Siliste, C., additional, Vinereanu, D., additional, Menezes Junior, A., additional, Castro Carneiro, A. R., additional, De Oliveira, B. L., additional, Shah, A. N., additional, Kantharia, B., additional, De Lucia, R., additional, Soldati, E., additional, Segreti, L., additional, Di Cori, A., additional, Zucchelli, G., additional, Viani, S., additional, Paperini, L., additional, Bongiorni, M. G., additional, Kutarski, A., additional, Czajkowski, M., additional, Pietura, R., additional, Malecka, B., additional, Heintze, J., additional, Eckardt, L., additional, Bauer, A., additional, Meine, M., additional, Van Erven, L., additional, Bloch Thomsen, P. E., additional, Lopez Chicharro, M. P., additional, Merhi, O., additional, Soga, Y., additional, Andou, K., additional, Nobuyoshi, M., additional, Gonzalez-Mansilla, A., additional, Martin-Asenjo, R., additional, Unzue, L., additional, Torres, J., additional, Garralda, E., additional, Coma, R. R., additional, Rodriguez Garcia, J. E., additional, Yaegashi, T., additional, Furusho, H., additional, Kato, T., additional, Chikata, A., additional, Takashima, S., additional, Usui, S., additional, Takamura, M., additional, Kaneko, S., additional, Chudzik, M., additional, Mitkowski, P., additional, Przybylski, A., additional, Lewek, J., additional, Smukowski, T., additional, Maciag, A., additional, Castrejon Castrejon, S., additional, Perez-Silva, A., additional, Estrada, A., additional, Doiny, D., additional, Ortega, M., additional, Lopez-Sendon, J. L., additional, Merino, J. L., additional, O'mahony, C., additional, Coats, C., additional, Cardona, M., additional, Garcia, A., additional, Calcagnino, M., additional, Lachmann, R., additional, Hughes, D., additional, Elliott, P. M., additional, Conti, S., additional, Pruiti, G. P., additional, Puzzangara, E., additional, Romano, S. A., additional, Di Grazia, A., additional, Ussia, G. P., additional, Tamburino, C., additional, Calvi, V., additional, Radinovic, A., additional, Sala, S., additional, Latib, A., additional, Mussardo, M., additional, Sora, S., additional, Paglino, G., additional, Gullace, M., additional, Colombo, A., additional, Ohlow, M.- A. G., additional, Lauer, B., additional, Wagner, A., additional, Schreiber, M., additional, Buchter, B., additional, Farah, A., additional, Fuhrmann, J. T., additional, Geller, J. C., additional, Nascimento Cardoso, R. M., additional, Batista Sa, L. A., additional, Campos Filho, L. F. C., additional, Rodrigues, S. V., additional, Dutra, M. V. F., additional, Borges, T. R. S. A., additional, Portilho, D. R., additional, Deering, T., additional, Bernardes, A., additional, Veiga, A., additional, Gartenlaub, O., additional, Goncalves, A., additional, Jimenez, A., additional, Rousseauplasse, A., additional, Deharo, J. C., additional, Striekwold, H., additional, Gosselin, G., additional, Sitbon, H., additional, Martins, V., additional, Molon, G., additional, Ayala-Paredes, F., additional, Sancho-Tello, M. J., additional, Fazal, I. A., additional, Brady, S., additional, Cronin, J., additional, Mcnally, S., additional, Tynan, M., additional, Plummer, C. J., additional, Mccomb, J. M., additional, Val-Mejias, J. E., additional, Oliveira, R. M., additional, Costa, R., additional, Martinelli Filho, M., additional, Silva, K. R., additional, Menezes, L. M., additional, Tamaki, W. T., additional, Mathias, W., additional, Stolf, N. A. G., additional, Misawa, T., additional, Ohta, I., additional, Shishido, T., additional, Miyasita, T., additional, Miyamoto, T., additional, Nitobe, J., additional, Watanabe, T., additional, Kubota, I., additional, Thibault, B., additional, Ducharme, A., additional, Simpson, C., additional, Stuglin, C., additional, Gagne, C. E., additional, Williams, R., additional, Mcnicoll, S., additional, Silvetti, M. S., additional, Drago, F., additional, Penela, D., additional, Bijnens, B., additional, Doltra, A., additional, Silva, E., additional, Berruezo, A., additional, Mont, L., additional, Sitges, M., additional, Mcintosh, R., additional, Baumann, O., additional, Raju, P., additional, Gurunathan, S., additional, Furniss, S., additional, Patel, N., additional, Sulke, N., additional, Lloyd, G., additional, Mor, M., additional, Dror, S., additional, Tsadok, Y., additional, Bachner-Hinenzon, N., additional, Katz, A., additional, Liel-Cohen, N., additional, Etzion, Y., additional, Mlynarski, R., additional, Mlynarska, A., additional, Wilczek, J., additional, Sosnowski, M., additional, Sinha, A. M., additional, Sinha, D., additional, Noelker, G., additional, Brachmann, J., additional, Weidemann, F., additional, Ertl, G., additional, Jones, M., additional, Searle, N., additional, Cocker, M., additional, Ilsley, E., additional, Foley, P., additional, Khiani, R., additional, Nelson, K. E., additional, Turley, A. J., additional, Owens, W. A., additional, James, S. A., additional, Linker, N. J., additional, Velagic, V., additional, Cikes, M., additional, Pezo Nikolic, B., additional, Puljevic, D., additional, Separovic-Hanzevacki, J., additional, Lovric-Bencic, M., additional, Biocina, B., additional, Milicic, D., additional, Kawata, H., additional, Chen, L., additional, Phan, H., additional, Anand, K., additional, Feld, G., additional, Birgesdotter-Green, U., additional, Fernandez Lozano, I., additional, Mitroi, C., additional, Toquero Ramos, J., additional, Castro Urda, V., additional, Monivas Palomero, V., additional, Corona Figueroa, A., additional, Hernandez Reina, L., additional, Alonso Pulpon, L., additional, Gate-Martinet, A., additional, Da Costa, A., additional, Rouffiange, P., additional, Cerisier, A., additional, Bisch, L., additional, Romeyer-Bouchard, C., additional, Isaaz, K., additional, Morales, M.- A., additional, Bianchini, E., additional, Startari, U., additional, Faita, F., additional, Bombardini, T., additional, Gemignani, V., additional, Piacenti, M., additional, Adhya, S., additional, Kamdar, R. H., additional, Millar, L. M., additional, Burchardt, C., additional, Murgatroyd, F. D., additional, Klug, D., additional, Kouakam, C., additional, Guedon-Moreau, L., additional, Marquie, C., additional, Benard, S., additional, Kacet, S., additional, Cortez-Dias, N., additional, Carrilho-Ferreira, P., additional, Silva, D., additional, Goncalves, S., additional, Valente, M., additional, Marques, P., additional, Carpinteiro, L., additional, Sousa, J., additional, Keida, T., additional, Nishikido, T., additional, Fujita, M., additional, Chinen, T., additional, Kikuchi, T., additional, Nakamura, K., additional, Ohira, H., additional, Takami, M., additional, Anjo, D., additional, Meireles, A., additional, Gomes, C., additional, Roque, C., additional, Pinheiro Vieira, A., additional, Lagarto, V., additional, Reis, H., additional, Torres, S., additional, Ortega, D. F., additional, Barja, L. D., additional, Montes, J. P., additional, Logarzo, E., additional, Bonomini, P., additional, Mangani, N., additional, Paladino, C., additional, Chwyczko, T., additional, Smolis-Bak, E., additional, Sterlinski, M., additional, Pytkowski, M., additional, Firek, B., additional, Jankowska, A., additional, Szwed, H., additional, Nakajima, I., additional, Noda, T., additional, Okamura, H., additional, Satomi, K., additional, Aiba, T., additional, Shimizu, W., additional, Aihara, N., additional, Kamakura, S., additional, Brzozowski, W., additional, Tomaszewski, A., additional, Wysokinski, A., additional, Bertoldi, E. G., additional, Rohde, L. E., additional, Zimerman, L. I., additional, Pimentel, M., additional, Polanczyk, C. A., additional, Boriani, G., additional, Lunati, M., additional, Gasparini, M., additional, Landolina, M., additional, Lonardi, G., additional, Pecora, D., additional, Santini, M., additional, Valsecchi, S., additional, Rubinstein, B. J., additional, Wang, D. Y., additional, Cabreriza, S. E., additional, Richmond, M. E., additional, Rusanov, A., additional, Quinn, T. A., additional, Cheng, B., additional, Spotnitz, H. M., additional, Kristiansen, H. M., additional, Vollan, G., additional, Hovstad, T., additional, Keilegavlen, H., additional, Faerestrand, S., additional, Brigesdotter-Green, U., additional, Nawar, A. M. R., additional, Ragab, D. A. L. I. A., additional, Eluhsseiny, R. A. N. I. A., additional, Abdelaziz, A. H. M. E. D., additional, Nof, E., additional, Abu Shama, R., additional, Buber, J., additional, Kuperstein, R., additional, Feinberg, M. S., additional, Barlev, D., additional, Eldar, M., additional, Glikson, M., additional, Badran, H., additional, Samir, R., additional, Tawfik, M., additional, Amin, M., additional, Eldamnhoury, H., additional, Khaled, S., additional, Tolosana, J. M., additional, Martin, A. M., additional, Hernandez-Madrid, A., additional, Macias, A., additional, Fernandez-Lozano, I., additional, Osca, J., additional, Quesada, A., additional, Padeletti, L., additional, Botto, G. L., additional, De Santo, T., additional, Szwed, A., additional, Martinez, J. G., additional, Degand, B., additional, Villani, G. Q., additional, Leclercq, C., additional, Ritter, P., additional, Watanabe, I., additional, Nagashima, K., additional, Okumura, Y., additional, Kofune, M., additional, Ohkubo, K., additional, Nakai, T., additional, Hirayama, A., additional, Mikhaylov, E., additional, Vander, M., additional, Lebedev, D., additional, Zarse, M., additional, Suleimann, H., additional, Bogossian, H., additional, Stegelmeyer, J., additional, Ninios, I., additional, Karosienne, Z., additional, Kloppe, A., additional, Lemke, B., additional, John, S., additional, Gaspar, T., additional, Rolf, S., additional, Sommer, P., additional, Hindricks, G., additional, Piorkowski, C., additional, Fernandez-Armenta, J., additional, Mont, L. L., additional, Zeljko, H., additional, Andreu, D., additional, Herzcku, C., additional, Boussy, T., additional, Brugada, J., additional, Obayahi, T., additional, Hegrenes, J., additional, Lim, E., additional, Mediratta, V., additional, Bautista, R., additional, Teplitsky, L., additional, Van Huls Van Taxis, C. F. B., additional, Wijnmaalen, A. P., additional, Gawrysiak, M., additional, Schuijf, J. D., additional, Bax, J. J., additional, Huo, Y., additional, Richter, S., additional, Arya, A., additional, Bollmann, A., additional, Akca, F., additional, Bauernfeind, T., additional, Schwagten, B., additional, De Groot, N. M. S., additional, Jordaens, L., additional, Szili-Torok, T., additional, Miller, S., additional, Kastner, G., additional, Maury, P., additional, Della Bella, P., additional, Delacretaz, E., additional, Sacher, F., additional, Maccabelli, G., additional, Brenner, R., additional, Rollin, A., additional, Jais, P., additional, Vergara, P., additional, Trevisi, N., additional, Ricco, A., additional, Petracca, F., additional, Bisceglia, C., additional, Baratto, F., additional, Salguero Bodes, R., additional, Fontenla Cerezuela, A., additional, De Riva Silva, M., additional, Lopez Gil, M., additional, Mejia Martinez, E., additional, Jurado Roman, A., additional, Montero Alvarez, M., additional, Arribas Ynsaurriaga, F., additional, Baszko, A., additional, Krzyzanowski, K., additional, Bobkowski, W., additional, Surmacz, R., additional, Zinka, E., additional, Siwinska, A., additional, Szyszka, A., additional, Perez Silva, A., additional, Estrada Mucci, A., additional, Ortega Molina, M., additional, Lopez Sendon, J. L., additional, Merino Llorens, J. L., additional, Kaitani, K., additional, Hanazawa, K., additional, Izumi, C., additional, Nakagawa, Y., additional, Yamanaka, I., additional, Hirahara, T., additional, Sugawara, Y., additional, Suga, C., additional, Ako, J., additional, Momomura, S., additional, Galizio, N., additional, Gonzalez, J., additional, Robles, F., additional, Palazzo, A., additional, Favaloro, L., additional, Diez, M., additional, Guevara, E., additional, Fernandez, A., additional, Greenberg, S., additional, Epstein, A., additional, Goldman, D. S., additional, Sangli, C., additional, Keeney, J. A., additional, Lee, K., additional, Piers, S. R. D., additional, Van Rees, J. B., additional, Thijssen, J., additional, Borleffs, C. J. W., additional, Van Der Velde, E. T., additional, Leclercq, C. H., additional, Hero, M., additional, Mizobuchi, M., additional, Enjoji, Y., additional, Yazaki, Y., additional, Shibata, K., additional, Funatsu, A., additional, Kobayashi, T., additional, Nakamura, S., additional, Amit, G., additional, Pertzov, B., additional, Zahger, D., additional, Medesani, L., additional, Rana, R., additional, Albano, F., additional, Fraguas, H., additional, Pedersen, S. S., additional, Hoogwegt, M. T., additional, Theuns, D. A. M. J., additional, Van Den Broek, K. C., additional, Tekle, F. B., additional, Habibovic, M., additional, Alings, M., additional, Van Der Voort, P., additional, Denollet, J., additional, Vrazic, H., additional, Jilek, C., additional, Lesevic, H., additional, Tzeis, S., additional, Semmler, V., additional, Gold, M. R., additional, Burke, M. C., additional, Bardy, G. H., additional, Varma, N., additional, Pavri, B., additional, Stambler, B., additional, Michalski, J., additional, Investigators, T. R. U. S. T., additional, Safak, E., additional, Schmitz, D., additional, Konorza, T., additional, Wende, C., additional, Schirdewan, A., additional, Neuzner, J., additional, Simmers, T., additional, Erglis, A., additional, Gradaus, R., additional, Goetzke, J., additional, Coutrot, L., additional, Goehl, K., additional, Bazan Gelizo, V., additional, Grau, N., additional, Valles, E., additional, Felez, M., additional, Sanjuas, C., additional, Bruguera, J., additional, Marti-Almor, J., additional, Chu, S. Y., additional, Li, P. W., additional, Ding, W. H., additional, Schukro, C., additional, Leitner, L., additional, Siebermair, J., additional, Stix, G., additional, Pezawas, T., additional, Kastner, J., additional, Wolzt, M., additional, Schmidinger, H., additional, Behar, N. A. T. H. A. L. I. E., additional, Kervio, G., additional, Petit, B., additional, Maison-Balnche, P., additional, Bodi, S., additional, Mabo, P., additional, Foley, P. W. X., additional, Mutch, E., additional, Brashaw-Smith, J., additional, Ball, L., additional, Leyva, F., additional, Kim, D. H., additional, Lee, M. J., additional, Lee, W. S., additional, Park, S. D., additional, Shin, S. H., additional, Woo, S. I., additional, Kwan, J., additional, Park, K. S., additional, Munetsugu, Y., additional, Tanno, K., additional, Kikuchi, M., additional, Ito, H., additional, Miyoshi, F., additional, Kawamura, M., additional, Kobayashi, Y., additional, Man, S., additional, Algra, A. M., additional, Schreurs, C. A., additional, Van Der Wall, E. E., additional, Cannegieter, S. C., additional, Swenne, C. A., additional, Iitsuka, K., additional, Kondo, T., additional, Goebbert, K., additional, Karossiene, Z., additional, Goldman, D., additional, Kallen, B., additional, Kerpi, E., additional, Sardo, J., additional, Arsenos, P., additional, Gatzoulis, K., additional, Manis, G., additional, Dilaveris, P., additional, Tsiachris, D., additional, Mytas, D., additional, Asimakopoulos, S., additional, Stefanadis, C., additional, Sideris, S., additional, Kartsagoulis, E., additional, Barbosa, O., additional, Marocolo Junior, M., additional, Silva Cortes, R., additional, Moraes Brandolis, R. A., additional, Oliveira, L. F., additional, Pertili Rodrigues De Resende, L. A., additional, Vieira Da Silva, M. A., additional, Dias Da Silva, V. J., additional, Hegazy, R. A., additional, Sharaf, I. A., additional, Fadel, F., additional, Bazaraa, H., additional, Esam, R., additional, Deshko, M. S., additional, Snezhitsky, V. A., additional, Stempen, T. P., additional, Kuroki, K., additional, Igawa, M., additional, Kuga, K., additional, Ferreira Santos, L., additional, Dionisio, T., additional, Nunes, L., additional, Machado, J., additional, Castedo, S., additional, Henriques, C., additional, Matos, A., additional, Oliveira Santos, J., additional, Kraaier, K., additional, Olimulder, M. A. G. M., additional, Galjee, M. A., additional, Van Dessel, P. F. H. M., additional, Van Der Palen, J., additional, Wilde, A. A. M., additional, Scholten, M. F., additional, Chouchou, F., additional, Poupard, L., additional, Philippe, C., additional, Court-Fortune, I., additional, Barthelemy, J.- C., additional, Roche, F., additional, Dolgoshey, T. S., additional, Madekina, G. A., additional, Sugiura, S., additional, Fujii, E., additional, Senga, M., additional, Dohi, K., additional, Sugiura, E., additional, Nakamura, M., additional, Ito, M., additional, Eitel, C., additional, Mendell, J., additional, Lasseter, K., additional, Shi, M., additional, Urban, L., additional, Hatala, R., additional, Hlivak, P., additional, De Melis, M., additional, Garutti, C., additional, Corbucci, G., additional, Mlcochova, H., additional, Maxian, R., additional, Arbelo, E., additional, Dogac, A., additional, Luepkes, C., additional, Ploessnig, M., additional, Chronaki, C., additional, Hinterbuchner, L., additional, Guillen, A., additional, Bun, S. S., additional, Latcu, D. G., additional, Franceschi, F., additional, Prevot, S., additional, Koutbi, L., additional, Ricard, P., additional, Saoudi, N., additional, Nazari, N., additional, Alizadeh, A., additional, Sayah, S., additional, Hekmat, M., additional, Assadian, M., additional, Ahmadzadeh, A., additional, Wnuk, M., additional, Jedrzejczyk-Spaho, J., additional, Kruszelnicka, O., additional, Piwowarska, W., additional, Fedorowski, A., additional, Burri, P., additional, Juul-Moller, S., additional, Melander, O., additional, Mitro, P., additional, Murin, P., additional, Kirsch, P., additional, Habalova, V., additional, Slaba, E., additional, Matyasova, E., additional, Barlow, M. A., additional, Blake, R. J., additional, Rostoff, P., additional, Wojewodka Zak, E., additional, Froidevaux, L., additional, Sarasin, F. P., additional, Louis-Simonet, M., additional, Hugli, O., additional, Yersin, B., additional, Schlaepfer, J., additional, Mischler, C., additional, Pruvot, E., additional, Occhetta, E., additional, Frascarelli, F., additional, Burali, A., additional, and Dovellini, E., additional

Published
2011
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28. Abstracts: Left Ventricular electro-mechanics

Author

Bertini, M., primary, Ajmone Marsan, N., additional, Nucifora, G., additional, Delgado, V., additional, Van Bommel, R. J., additional, Borleffs, C. J. W., additional, Schalij, M. J., additional, Bax, J. J., additional, Tops, L. F., additional, Trines, S. A., additional, Zeppenfeld, K., additional, Van Der Wall, E. E., additional, Costa, R., additional, Martinelli Filho, M., additional, Oliveira, R. M., additional, Silva, R. T., additional, Silva, K. R., additional, Guerra, V. C., additional, Menezes, L., additional, Stolf, N. A. G., additional, Pastore, G., additional, Baracca, E., additional, Aggio, S., additional, Imbimbo, G., additional, Comisso, J., additional, Zanon, F., additional, Prinzen, F. W., additional, Mills, R. W., additional, Mulligan, L. M., additional, Cornelussen, R. N., additional, Van Wijk, F., additional, Van Hunnik, A., additional, Kuiper, M., additional, Lampert, A., additional, Anselmino, M., additional, Shek Yussuf Guled, A., additional, Cerrato, E., additional, Antolini, M., additional, Tizzani, E., additional, Amellone, C., additional, Massa, R., additional, and Golzio, P. G., additional

Published
2009
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29. Poster Session 2: Results (pacing), indications (pacing)

Author

Sankaranarayanan, R., primary, James, M. A., additional, Burtchaell, S., additional, Holloway, R., additional, Hoyt, R. H., additional, Mchenry, B., additional, Fedewa, M. M., additional, Penot, J. P., additional, Jacquot, C., additional, Bonet, J. F., additional, Pochet, H., additional, Jean, S., additional, Fressonnet, R., additional, Penot, M. P., additional, Weiss, A., additional, Abecasis, J. A., additional, Leal, S., additional, Monge, J., additional, Fartouce, S., additional, Santos, J. M., additional, Silva, A., additional, Costa, R., additional, Leao, M. I. P., additional, Mori, R. F., additional, Giannini, G., additional, Costa, S. P. L., additional, Silva, K. R., additional, Penteado, I. M., additional, Palka, P., additional, Lange, A., additional, Donnelly, J. E., additional, Adsett, M., additional, Hayes, J. R., additional, Stafford, W. J., additional, Hirayama, Y., additional, Kawamura, Y., additional, Sato, N., additional, Saito, T., additional, Hotta, D., additional, Kikuchi, K., additional, Ohori, K., additional, Hasebe, N., additional, Cabrera Bueno, F., additional, Alzueta, J., additional, Fernandez-Pastor, J., additional, Pena-Hernandez, J. L., additional, Molina-Mora, M. J., additional, Barrera, A., additional, De Teresa, E., additional, Ayala Paredes, F., additional, Roux, J. F., additional, Scazzuso, F., additional, Lavallee, L., additional, Poirier, M., additional, Chaumont, J., additional, Iorgulescu, C., additional, Vasile, A., additional, Dorobantu, M., additional, Vatasescu, R.- G., additional, Lefflerova, K., additional, Lupinek, P., additional, Bytesnik, J., additional, Cihak, R., additional, Krausova, R., additional, Vancura, V., additional, Kautzner, J., additional, Blich, M., additional, Suleiman, M., additional, Zeidan Shwiri, T., additional, Marai, I., additional, Boulos, M., additional, Amikam, S., additional, Lilli, A., additional, Magnacca, M., additional, Svetlich, C., additional, D'addario, S., additional, Baratto, M. T., additional, Ghidini Ottonelli, A., additional, Savino, K., additional, Casolo, G., additional, Wolber, T., additional, On, C., additional, Binggeli, C., additional, Holzmeister, J., additional, Brunckhorst, C., additional, and Duru, F., additional

Published
2009
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32. Streptomyces drozdowiczii sp. nov., a novel cellulolytic streptomycete from soil in Brazil

Author

Semêdo, L. T. A. S., primary, Gomes, R. C., additional, Linhares, A. A., additional, Duarte, G. F., additional, Nascimento, R. P., additional, Rosado, A. S., additional, Margis-Pinheiro, M., additional, Margis, R., additional, Silva, K. R. A., additional, Alviano, C. S., additional, Manfio, G. P., additional, Soares, R. M. A., additional, Linhares, L. F., additional, and Coelho, R. R. R., additional

Published
2004
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33. Apoptosis in subicular neurons: A comparison between suicide and Addison's disease.

Author

Printha, K., Hulathduwa, S. R., Samarasinghe, K., Suh, Y. H., and De Silva, K. R. D.

Subjects
APOPTOSIS, SUICIDE, ADDISON'S disease, PSYCHOLOGICAL stress, HIPPOCAMPUS (Brain), ADRENOCORTICAL hormones, SUICIDE victims, MEDICAL research
Abstract

Background: Stress and depression shows possible links to neuronal death in hippocampus. Subiculum plays a prominent role in limbic stress integration and direct effect of corticosteroids on subicular neurons needs to be defined to assess its subsequent impact on hippocampal plasticity. Aim: This study was intended to assess apoptosis in subicular neurons of a young depressed suicide victim, where presumably stress induced excess of corticosteroids and a case of young Addison's disease with low level of corticosteroids. Materials and Method: Both bilateral adrenal glands (Addison's) and subiculum (both cases) were initially stained with hematoxylin and eosin; subicular neurons of both cases were examined for the degree of apoptosis using 'ApopTag Kit'. Apoptotic cell counts were expressed as average number of labeled cells/mm² and the results were analysed statistically using a non-parametric Mann-Whitney U test. Result: Apoptotic neurons were detected in the subicular region of both suicide and Addison victims, and it is statistically significant in both right and left between the cases (P < 0.05). In suicide victim, the neuronal apoptosis is considerably significant between the two hemispheres (P < 0.05), in contrast to Addison disease where the number of neuronal cell death between right and left was statistically insignificant (P > 0.05). Conclusion: The present study confirms the vulnerability of the subicular neurons to apoptosis, possibly due to corticosteroids in both ends of spectrum. [ABSTRACT FROM AUTHOR]

Published
2009
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34. Variation in the origin of the posterior cerebral artery in adult Sri Lankans.

Author

De Silva, K. R. D., Silva, T. R. N., Gunasekera, W. S. L., and Jayesekera, R. W.

Subjects
*CAROTID artery, *ISCHEMIA, *INFARCTION, *AUTOPSY, *NEUROLOGY, *CEREBROVASCULAR disease, *BLOOD circulation disorders
Abstract

Background: The degree of contribution from the vertebro-basilar and carotid systems to the origin of the posterior cerebral artery (PCA) is of clinico-anatomical importance. Three configurations in the bifurcation of the posterior communicating artery (PcomA) have been described, foetal, transitional and adult. Objective: To examine the extent of contribution from the vertebro-basilar and carotid systems to the origin of the PCA in adult autopsy brains in subjects who had died of causes unrelated to the brain. Materials and Methods: The external diameter of the PcomA, pre communicating part (P1) and the post communicating part (P2) of PCA in 225 normal Sri Lankan adult cadaver brains was measured using a calibrated grid. Results: The adult configuration was present in 220 (93.3%); (bilaterally in 200 (88.8%), and unilaterally in 20 (8.8%) ten on each side. Foetal configuration was seen in 17 (4.4%); bilaterally in 3 (1.3%), and unilaterally in 14 (6%) 8 on the left and 6 on the right. Transitional configuration was seen in 8 (2.2%); bilaterally in 2 (0.9%), and unilaterally in 6 (2.5%) 2 on the left and 4 on the right. Conclusion: This study reveals that the internal carotid artery (ICA) provided the major supply to the PCA in 4.4% of foetal and 2.2% of transitional configurations. The adult configuration was present in 220 (93.3%), the highest recorded in the literature. This finding may be of relevance to vertebrobasilar ischaemia and infarcts in the territory of the PCA. [ABSTRACT FROM AUTHOR]

Published
2009
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35. Fraqueza muscular esquelética e intolerância ao exercício em pacientes com doença pulmonar obstrutiva crônica.

Author

Silva, K. R., Marrara, K. T., Marino, D. M., V. A. P., Di Lorenzo, and Jamami, M.

Subjects
*MUSCULOSKELETAL system, *EXERCISE, *OBSTRUCTIVE lung diseases, *NUTRITIONAL assessment, *RESPIRATORY muscles, *QUADRICEPS muscle
Abstract

The aim of this study was to evaluate the functional capacity and the performance of respiratory and quadriceps muscles in patients with chronic obstructive pulmonary disease (COPD) and relate them to nutritional status and forced expiratory volume in the first second (FEV1). Methods: Twelve patients with moderate COPD (70±7 years, FEV1 52±17% predicted, body mass index (BMI) 23±4kg/m²) and seven healthy volunteers (69±8 years, FEV1 127±12% predicted, BMI 27±3kg/m²) were evaluated. All of them underwent body composition analysis, measurement of respiratory muscle strength (maximum inspiratory pressure, MIP, and maximum expiratory pressure, MEP), cardiorespiratory exercise test (CET) and evaluation of palm grip strength, peak torque and total work or endurance of the quadriceps femoris. Results: The patients with COPD had lower values for the free-fat mass (FFM) index (18±1 versus 21±1 kg/m², p≤0.05), maximum load attained in the CET (60±20 versus 102±18 watts, p≤0.01), MIP (58±19 versus 87±21cmH20, p≤0.05), palm grip strength (38±6 versus 47±5kg, p≤0.05), peak torque (103±21 versus 138±18Nm, p≤0.05) and total work of the quadriceps femoris (1570±395 versus 2333±568J, p≤0.05) when compared with the control group (independent Student's t test). There was no correlation between FEV1 and the variables studied, while the FFM correlated with the total work of the quadriceps (Pearson, r=0.6290, p≤0.05). Conclusions: These results indicate that patients with COPD show weakness of the inspiratory and quadriceps muscles and lower functional capacity, when compared with a healthy group. Moreover, they suggest that the degree of airflow obstruction is not a good predictor for quantifying the nutritional and muscle impairments in patients with COPD. [ABSTRACT FROM AUTHOR]

Published
2008
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36. Validation of the Geriatric Depression Scale for an elderly Sri Lankan clinic population.

Author

Kulathunga, M., Umayal, S., Somaratne, S., Srikanth, S., Kathriarachchi, S., and De Silva, K. R. D.

Subjects
DIAGNOSIS of mental depression, COMMUNITY health services, DEPRESSION in old age, POPULATION, PSYCHOLOGICAL tests, RESEARCH funding, RECEIVER operating characteristic curves, RESEARCH methodology evaluation, OLD age
Abstract

Background: Geriatric Depression Scale (GDS) has not been validated for the elderly population in Sri Lanka. Aim: To translate, validate, and examine the effectiveness of GDS and to suggest the optimal cut-off scores for elderly Sri Lankans attending a psychogeriatric clinic. Materials and Methods: The Sinhalese translation of GDS (GDS-S) was administered to people aged 55 years and above, attending a psychogeriatric outpatient clinic. The diagnostic performance of the instrument was compared against the ICD 10 diagnosis of a consultant psychiatrist, which was considered the 'gold standard'. Receiver operating characteristic (ROC) analysis was carried out to compare the diagnostic performance of the GDS-S. Optimal cut-off scores for depression and sensitivity and the specificity of the instrument was determined. Results: A total of 60 subjects formed the final sample (male/female=16/44) of which 30 were depressed, while 30 were age- and sex-matched controls. The optimal cut-off score for GDS-S was 8 for differentiating non-depressed from mildly depressed, while the cut-off score for moderate depression was 10. Sensitivity and specificity of GDS-S was 73.3% for differentiating depressed from non-depressed. Conclusion: GDS is culturally acceptable, easy to use, sensitive, and a valid instrument to diagnose depression and to differentiate mild from moderate depression in an elderly Sri Lankan clinic population. [ABSTRACT FROM AUTHOR]

Published
2010
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49. IMUNIDADE INDUZIDA PELA USO COMBINADO DE VACINA ATENUADA (ESTIRPE MASSACHUSETTS) E VACINA INATIVADA EXPERIMENTAL (VARIANTE BR-I) CONTRA O DESAFIO COM ESTIRPE VARIANTE BRASILEIRA DO VÍRUS DA BRONQUITE INFECCIOSA AVIÁRIA.

Author

DOS SANTOS, R. M., SILVA, K. R., LOPES, P. D., FERNANDO, F. S., BORZI, M. M., MONTASSIER, M. F. S., OKINO, C. H., and MONTASSIER, H. J.

Abstract

Há atualmente no Brasil, uma predominância de infecções causadas por estirpes do VBI classificadas no genótipo variante (BR-I), que revelam diferenças marcantes de antigenicidade com relação à estirpe vacinal Massachusetts, rotineiramente usada em nosso país. Isso resulta em uma baixa imunidade-cruzada e consequentemente em um menor nível de proteção contra isolados desse genótipo. O propósito deste trabalho foi testar uma vacina inativada contendo uma estirpe variante do VBI pertencente ao genótipo BR-I, e avaliar o estado de proteção induzido por esta vacina em combinação com a vacina atenuada Massachusetts em aves desafiadas com estirpe homóloga. Foram testadas aves SPF distribuídas em três grupos: grupo A (aves vacinadas ao 1° dia de idade com vacina atenuada comercial, revacinadas com 14 dias de idade com vacina inativada experimental e desafiadas aos 35 dias de idade); grupo B (aves não vacinadas e desafiadas aos 35 dias de idade); grupo C (controle). As aves de cada grupo foram sacrificadas aos 3, 7 e 11 dias pós-infecção, para colheita de amostras de traquéia, rins, soro e lágrima, e posteriormente avaliação histopatológica e das respostas imunes humoral(RIH) pelo ELISA e celular(RIC) pela expressão de genes de RIC. Os resultados deste estudo demonstraram que esse esquema imunoprofilático induziu aumentos significativos nos níveis de anticorpos lacrimais e séricos do isótipo IgG anti-VBI e também na expressão dos genes relacionados às respostas imunes cito-mediadas, (CD8 e da Granzima A), nas aves vacinadas, que se mostraram associados com a diminuição de lesões histológicas e uma menor carga viral na traqueia e rins das aves vacinadas e desafiadas. Concluiu-se que as RIH e RIC de memória conferidas pela vacinação combinada da estirpe atenuada Massachusetts e da variante IBVPR-05 induziu um estado de proteção efetivo contra a infecção por esta variante, tendo o potencial de proporcionar proteção contra outras variantes do VBI. [ABSTRACT FROM AUTHOR]

Published
2015
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50. Effectiveness of epicardial atrial pacing using a bipolar steroid-eluting endocardial lead with active fixation in an experimental model.

Author

Bueno, S. C. P., Tamaki, W. T., Silva, M. F. A, Zambolim, C. M, Silva, K. R, Filho, M. Martinelli, Costa, R., and Jatene, F. B.

Subjects
ENDOCARDIUM, STEROIDS
Abstract

An abstract of the article "Effectiveness of epicardial atrial pacing using a bipolar steroid-eluting endocardial lead with active fixation in an experimental model" by S. C. P. Bueno and colleagues is presented.

Published
2013
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