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2. Unibody Endograft Using AFX 2 for Less Invasive and Faster Endovascular Aortic Repair: Protocol for a Multicenter Nonrandomized Study

Author

Silingardi, Roberto, Sirignano, Pasqualino, Andreoli, Francesco, Mansour, Wassim, Migliari, Mattia, and Speziale, Francesco

Subjects
Medicine, Computer applications to medicine. Medical informatics, R858-859.7
Abstract

BackgroundSince the introduction of endovascular aortic repair (EVAR) for treatment of abdominal aortic aneurysms (AAAs), progressive improvements in results have been achieved. However, conventional bifurcated stent grafts have been proven to have a nonnegligible risk of failure and secondary intervention, principally due to the lack of adequate proximal sealing. The unique AFX 2 Endovascular AAA System (Endologix, Irvine, CA) unibody device, which provides different sealing and fixation features compared with conventional devices, seems to overcome these limitations. ObjectiveThe aim of this study is to evaluate intraoperative, perioperative, and postoperative results in patients treated with the AFX 2 Endovascular AAA System endografts for elective AAA repair in a large cohort of consecutive patients. MethodsAll eligible EVAR patients will be included in this observational, multicenter, prospective, nonrandomized study. The number of patients to be enrolled is 500. ResultsThe primary endpoint of the study is to evaluate the technical and clinical success of EVAR with unibody endografts in short- (90-day), mid- (1-year), and long-term (5-year) follow-up periods. The following secondary endpoints will also be addressed: operative time, intraoperative radiation exposure, contrast medium usage, AAA sac shrinkage at 12-month and 5-year follow-up, and any potential role of patients’ baseline characteristics and device configuration on primary endpoint. The actual start date of the investigation was November 2019. The final patient is expected to be treated by the end of December 2020, and the estimated study completion date is December 2025. ConclusionsThis study will provide verified real-world data on AAAs treated by AFX 2 endografts and followed for a long-term interval. International Registered Report Identifier (IRRID)PRR1-10.2196/16959

Published
2020
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3. Outcomes of off-the-shelf preloaded inner branch device for urgent endovascular thoraco-abdominal aortic repair in the ItaliaN Branched Registry of E-nside EnDograft

Author

Antonello, Michele, Piazza, Michele, Squizzato, Francesco, Spezia, Matteo, Grego, Franco, Pratesi, Giovanni, Spinella, Giovanni, Esposito, Davide, Bastianon, Martina, Tshomba, Yamume, Donati, Tommaso, Sica, Simona, Tinelli, Giovanni, Ferri, Michelangelo, Quaglino, Simone, Gaggiano, Andrea, Vento, Vincenzo, Carbonari, Luciano, Gatta, Emanuele, Lenti, Massimo, Simonte, Gioele, Isernia, Giacomo, Parlani, Giambattista, Piffaretti, Gabriele, Frigatti, Paolo, Scrivere, Paola, Furlan, Federico, Veraldi, Gian Franco, Mezzetto, Luca, Gennai, Stefano, Leone, Nicola, Silingardi, Roberto, Iacono, Gustavo, Turricchia, Giorgio Ubaldo, Angiletta, Domenico, Maione, Massimo, Apostolou, Dimitri, Pulli, Raffaele, Fargion, Aaron, Filippi, Federico, De Angelis, Filippo, Arici, Vittorio, Bozzani, Antonio, Luigi Molinari, Alessandro Carlo, Rossi, Giovanni, Costantini Brancadoro, Emidio, Ferraris, Matteo, Dorrucci, Vittorio, Derone, Graziana, Tolva, Valerio Stefano, Compagnoni, Nicola Monzio, Segramora, Vittorio Maria, Deleo, Gaetano, Bracale, Umberto, Guzzardi, Giuseppe, Ferrer, Ciro, Giudice, Rocco, Sbarigia, Enrico, Cuozzo, Simone, Gattuso, Roberto, Mansour, Wassim, Di Marzo, Luca, Grimaldi, Sabrina, Corona, Mario, Chisci, Emiliano, Mechelagnoli, Stefano, De Donato, Gianmarco, Palasciano, Giancarlo, Pasqui, Edoardo, Candeloro, Laura, Ricci, Carmelo, Neri, Eugenio, Mangialardi, Nicola, Orrico, Matteo, Ronchey, Sonia, Fazzini, Stefano, Ippoliti, Arnaldo, Discalzi, Andrea, Rossato, Denis, Vio, Elias, Galeazzi, Edoardo, Farneti, Fabrizio, Bertoglio, Luca, Volpe, Pietro, Massara, Mafalda, Milite, Domenico, and Xodo, Andrea

Published
2024
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4. Endograft Thrombosis as an Indication for Open Conversion after Endovascular Aneurysm Repair in a Multicenter Experience over 25 Years

Author

Mersanne, Arianna, Gerosa, Cecilia, Mariani, Erica, Faggioli, Gianluca, Ancetti, Stefano, Migliari, Mattia, Gennai, Stefano, Chisci, Emiliano, Melloni, Andrea, Attisani, Luca, Piffaretti, Gabriele, Mauri, Francesca, Troisi, Nicola, Berchiolli, Raffaella, Fanelli, Mara, Paciaroni, Elisa, Marchetti, Federica, Fornasari, Anna, Perini, Paolo, Gargiulo, Mauro, Silingardi, Roberto, Michelagnoli, Stefano, Bonardelli, Stefano, Bellosta, Raffaello, and Freyrie, Antonio

Published
2024
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6. Editor's Choice – Outcomes of Off the Shelf Outer Branched Versus Inner Branched Endografts in the Treatment of Thoraco-Abdominal Aortic Aneurysm in the B.R.I.O. (BRanched Inner – Outer) Study Group

Author

Spertino, Andrea, Grego, Franco, Esposito, Davide, Bastianon, Martina, Lenti, Massimo, Isernia, Giacomo, Ferrer, Ciro, Piffaretti, Gabriele, Mauri, Francesca, Mezzetto, Luca, Mastrorilli, Davide, Silingardi, Roberto, Leone, Nicola, Tshomba, Yamume, Donati, Tommaso, Sica, Simona, Tinelli, Giovanni, Pulli, Raffaele, Fargion, Aaron, Pratesi, Carlo, Di Marzo, Luca, Di Girolamo, Alessia, Orticelli, Assunta, Michelagnoli, Stefano, Chisci, Emiliano, Fazzini, Stefano, Oddi, Fabio Massimo, Ippoliti, Arnaldo, Piazza, Michele, Squizzato, Francesco, Pratesi, Giovanni, Parlani, Gianbattista, Simonte, Gioele, Giudice, Rocco, Mansour, Wassim, Veraldi, Gian Franco, Gennai, Stefano, and Antonello, Michele

Published
2024
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11. Bypass vs endovascular treatment for occluded femoro-popliteal stents in patients with critical limb-threatening ischemia

Author

Abualhin, Mohammad, Andreini, Marco, Bastianon, Martina, Calvagna, Cristiano, Colacchio, Chiara, D'Andrea, Alessia, Esposito, Andrea, Caneva, Patrizia Dalla, Fazzini, Stefano, Ferrer, Ciro, Gallitto, Enrico, Gennai, Stefano, Giordano, Antonio Nicola, Leone, Nicola, Mastrorilli, Davide, Melani, Caterina, Mena Vera, Jorge Miguel, Mezzetto, Luca, Parlani, Gianbattista, Scarati, Valentina, Sica, Simona, Simonte, Gioele, Squizzato, Francesco, Spath, Paolo, Thsomba, Yamume, Visciglia, Elvira, Zanetti, Elisa, D’Oria, Mario, Berchiolli, Raffaella, Gargiulo, Mauro, Antonello, Michele, Pratesi, Giovanni, Michelagnoli, Stefano, Silingardi, Roberto, Isernia, Giacomo, Veraldi, Gian Franco, Tinelli, Giovanni, Giudice, Rocco, Ippoliti, Arnaldo, Cappiello, Pierluigi, Martelli, Massimiliano, Lepidi, Sandro, and Troisi, Nicola

Published
2023
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13. Penumbra Indigo Percutaneous Aspiration Thrombectomy System in the treatment of Aortic Endograft Iliac Limb Occlusion: Results from an Italian Multicentre Registry

Author

Spath, Paolo, Angiletta, Domenico, Chegai, Fabrizio, De Donato, Gianmarco, D’Oria, Mario, Faggioli, Gianluca, Gallitto, Enrico, Isernia, Giacomo, Lepidi, Sandro, Migliari, Mattia, Pasqui, Edoardo, Pini, Rodolfo, Silingardi, Roberto, Simonte, Gioele, Spinazzola, Angelo, Gargiulo, Mauro, and de Donato, Gianmarco

Published
2023
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15. Editor's Choice – Early Outcomes of a Novel Off the Shelf Preloaded Inner Branch Endograft for the Treatment of Complex Aortic Pathologies in the ItaliaN Branched Registry of E-nside EnDograft (INBREED)

Author

Forcella, Edoardo, Grego, Franco, Spinella, Giovanni, Di Gregorio, Sara, Donati, Tommaso, Sica, Simona, Tinelli, Giovanni, Ferri, Michelangelo, Quaglino, Simone, Vento, Vincenzo, Carbonari, Luciano, Lenti, Massimo, Isernia, Giacomo, Parlani, Giambattista, Scrivere, Paola, Furlan, Federico, Mezzetto, Luca, Mastrorilli, Davide, Gennai, Stefano, Leone, Nicola, Iacono, Gustavo, Turricchia, Giorgio Ubaldo, Angiletta, Domenico, Maione, Massimo, Apostolou, Dimitri, Pulli, Raffaele, Fargion, Aaron, Pratesi, Carlo, Filippi, Federico, De Angelis, Filippo, Arici, Vittorio, Bozzani, Antonio, Luigi Molinari, Alessandro Carlo, Rossi, Giovanni, Brancadoro, Emidio Costantini, Ferraris, Matteo, Dorrucci, Vittorio, Derone, Graziana, Tolva, Valerio Stefano, Segramora, Vittorio Maria, Deleo, Gaetano, Bracale, Umberto, Guzzardi, Giuseppe, Ferrer, Ciro, Giudice, Rocco, Sbarigia, Enrico, Cuozzo, Simone, Gattuso, Roberto, Mansour, Wassim, Di Marzo, Luca, Grimaldi, Sabrina, Corona, Mario, Chisci, Emiliano, Mechelagnoli, Stefano, De Donato, Gianmarco, Palasciano, Giancarlo, Pasqui, Edoardo, Candeloro, Laura, Ricci, Carmelo, Neri, Eugenio, Mangialardi, Nicola, Orrico, Matteo, Fazzini, Stefano, Ippoliti, Arnaldo, Discalzi, Andrea, Rossato, Denis, Vio, Elias, Galeazzi, Edoardo, Farneti, Fabrizio, Piazza, Michele, Squizzato, Francesco, Pratesi, Giovanni, Tshomba, Yamume, Gaggiano, Andrea, Gatta, Emanuele, Simonte, Gioele, Piffaretti, Gabriele, Frigatti, Paolo, Veraldi, Gian Franco, Silingardi, Roberto, and Antonello, Michele

Published
2023
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16. Midterm results on a new self-expandable covered stent combined with branched stent grafts: Insights from a multicenter Italian registry

Author

Angiletta, Domenico, Chiesa, Roberto, Di Marzo, Luca, Flora, Loris, Gennai, Stefano, Giudice, Rocco, Lenti, Massimo, Leone, Nicola, D’Oria, Mario, Lepidi, Sandro, Melloni, Andrea, Mezzetto, Luca, Michelagnoli, Stefano, Migliara, Bruno, Milite, Domenico, Pacini, Davide, Palazzo, Enzo, Pecchio, Alberto, Pegorer Matteo, Alberto, Perini, Paolo, Piazza, Michele, Pratesi, Giovanni, Ronchey, Sonia, Spadoni, Nicola, Tusini, Nicola, Verzini, Fabio, Bertoglio, Luca, Grandi, Alessandro, Veraldi, Gian Franco, Pulli, Raffaele, Antonello, Michele, Bonvini, Stefano, Isernia, Giacomo, Bellosta, Raffaello, Buia, Francesco, and Silingardi, Roberto

Published
2023
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17. Preliminary results from an Italian National Registry on the outcomes of the Najuta fenestrated aortic arch endograft

Author

Mangialardi, Nicola, Orrico, Matteo, Isernia, Giacomo, Simonte, Gioele, Lenti, Massimo, Parlani, Gianbattista, Fino, Gianluigi, Baccani, Luigi, Leonardi, Paolo, Silingardi, Roberto, Covic, Tea, Gennai, Stefano, Gaggiano, Andrea, Ferri, Michelangelo, Ferrero, Emanuele, Quaglino, Simone, Rizza, Antonio, Maritati, Gabriele, Portoghese, Michele, Verzini, Fabio, Pulli, Raffaele, Fargion, Aaron, Bonvini, Stefano, Intrieri, Francesco, Speziale, Francesco, Mansour, Wassim, Moniaci, Diego, Berchiolli, Raffaella, Troisi, Nicola, Colli, Andrea, Camparini, Stefano, Pratesi, Giovanni, Massi, Francesco, Michelagnoli, Stefano, Chisci, Emanuele, Bonardelli, Stefano, Maione, Massimo, and Angiletta, Domenico

Published
2023
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20. Multicenter comparison between open conversions and semi-conversions for late endoleaks after endovascular aneurysm repair

Author

Mariani, Erica, Faggioli, GianLuca, Gallitto, Enrico, Migliari, Mattia, Gennai, Stefano, Paro, Barbara, Baggi, Paolo, Attisani, Luca, Pegorer, Matteo, Tadiello, Marco, Franchin, Marco, Bonvini, Stefano, Chisci, Emiliano, Troisi, Nicola, Fontana, Antonio, Strozzi, Francesco, Scabini, Matteo, Mosso, Federico, Paciaroni, Elisa, Tarantini, Salvatore, Leone, Michele, Masi, Giancarlo, Perini, Paolo, Gargiulo, Mauro, Silingardi, Roberto, Bonardelli, Stefano, Bellosta, Raffaello, Piffaretti, Gabriele, Michelagnoli, Stefano, Tusini, Nicola, Capelli, Patrizio, Turicchia, Giorgio Ubaldo, and Freyrie, Antonio

Published
2022
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21. One-year results of the INSIGHT study on endovascular treatment of abdominal aortic aneurysms

Author

Becquemin, Jean-Pierre, Bühler, Christoph, Chiesa, Roberto, Cieri, Enrico, Coppi, Gioacchino, de Blas, Mariano, Dias, Nuno, Ducasse, Eric, Garcia, Ignacio, Hamady, Mohamad, Ippoliti, Arnaldo, Knippenberg, Bob, Kolvenbach, Ralf, Lakshminarayan, Raghuram, Lorido, Antonio, Midy, Dominique, Mosquera, Nilo, Oberhuber, Alexander, Pogany, Gabriele, Pratesi, Carlo, Resch, Tim, Riambau, Vincenc, Roos, Håkan, Philipp Schäfer, Jost, Scheinert, Dierk, Silingardi, Roberto, Sultan, Sherif, Verzini, Fabio, Vona, Alessio, Warlé, Michiel, Wikkeling, Marald, Wilkins, Jason, Torsello, Giovanni, Bertoglio, Luca, Kellersmann, Richard, Wever, Jan J., van Overhagen, Hans, and Stavroulakis, Konstantinos

Published
2022
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22. Comprehensive Learning Curve Analysis of a Long-Term Experience With Thoracic Endovascular Aneurysm Repair.

Author

Gennai, Stefano, Leone, Nicola, Bartolotti, Luigi AM, Andreoli, Francesco, Migliari, Mattia, and Silingardi, Roberto

Abstract

Purpose: To analyze the learning curve for thoracic endovascular aortic repair (TEVAR) in a single center over a period of 25 years. Materials and Methods: In total, 390 consecutive standard TEVAR procedures undertaken between 1996 and 2021 were included in a retrospective, observational, single-center study. Cumulative sum charts were elaborated for the entire center experience (primary outcome) as well as for the first and second implanting physicians. Data on procedural variables (contrast volume, operative and fluoroscopy time), 30-day major adverse events (MAEs) and clinical success, and endoleak and reintervention rates were secondary outcomes and subdivided into 4 quartiles of experience (Q1–Q4) or presented as first 2 versus latest 2 quartiles (Q1–Q2 vs Q3–Q4). Results: The mean follow-up was 4.3±4.0 years. The center's learning curve was achieved after 75 procedures, and it was similar for the first implanting physician. The surgeon coming thereafter had a significantly shorter curve (10 TEVARs). Comparing Q1–Q2 with Q3–Q4, 30-day MAEs (16.1 vs 11.3%, p=0.164), 30-day mortality (11.4% vs 3.6%, p=0.003), and intraoperative additional maneuvers (21.5% vs 13.3%, p=0.033) were reduced along with an improvement in clinical success (85.9% vs 90.3%, p=0.190). From Q1 to Q4, operative time (139.8±65.5 to 76.7±43.7 min, p=0.001), fluoroscopy time (15.1±8.8 to 7.1±5.1 min, p<0.001), and contrast volume (244.0±112.1 to 104.3±46.1 mL, p<0.001) showed a considerable reduction. Late endoleak and aortic-related mortality declined significantly from Q1–Q2 to Q3–Q4 (24.1% to 15.5%, p=0.033 and 18.6% vs 8.2%, p=0.006, respectively). Operative time (p=0.021), contrast volume (p=0.016), and fluoroscopy time (p=0.004) were independent risk factors for endoleak, causing a 1.3-fold risk increase for both each 60 minutes of additional operative time (p=0.021) and every 100 mL of additional contrast medium (p=0.016). Each 10-minute increase in fluoroscopy time determined a 1.4-fold risk increment (p=0.004). Conclusion: The learning curve shortened significantly over time with non-negligible clinical outcome improvements, suggesting that specific endovascular training is mandatory to become an effective TEVAR performer. Clinical Impact: For the first time in literature, the standard TEVAR's learning curve has been evaluated at a single vascular surgery center over a period of 25 years. The learning curve for the center and the first physician historically undertaking TEVAR was achieved at the 75th treated patient. The learning curve of the surgeons coming thereafter was significantly shorter (10 cases). This quarter-century demonstrated that intraoperative learning-related variables were associated with long-term clinical outcomes and all have improved over time. Centers approaching TEVAR for the first time and training program providers could use these data to aim to offer better clinical outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
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23. Iliac Branch Devices in the Repair of Ruptured Aorto-iliac Aneurysms: A Multicenter Study.

Author

Karelis, Angelos, Sonesson, Björn, Gallitto, Enrico, Tsilimparis, Nikolaos, Forsell, Claes, Leone, Nicola, Silingardi, Roberto, Mesnard, Thomas, Sobocinski, Jonathan, Isernia, Giacomo, Resch, Timothy, Gargiulo, Mauro, and Dias, Nuno V.

Abstract

Purpose: To evaluate the outcomes of preserving the internal iliac artery (IIA) with iliac branched devices (IBDs) during acute endovascular repair of ruptured aortoiliac aneurysms. Material and Methods: This is a multicenter retrospective review of all consecutive patients undergoing acute endovascular repair of ruptured aortoiliac aneurysm with an IBD at 8 aortic centers between December 2012 and June 2020. A control group was used where the IIA was intentionally occluded from the same study period. The main outcome measures were 30-day mortality, major adverse events, technical success, and clinical success. Secondary outcomes were buttock claudication, primary patency, primary-assisted and secondary patency of the IBD, occurrence of endoleak types I/III, and reintervention. Values are presented as numbers and percentages or interquartile range in parenthesis. Results: Forty-eight patients were included in the study: 24 with IBD and 24 with IIA occlusion. There was no difference in demographics, cardiovascular risk factors, and aneurysm extent. Twenty (83%) of them were hemodynamically stable during the procedure as opposed to 14 (58%, p=.23) with the IIA occlusion. Technical success was achieved in all cases with a procedure time of 180 (133–254) minutes, 45 (23–65) of which were from IBD. There were 2 (8%) deaths during the first 30 days and 2 (8%) major complications unrelated to the IBD, whereas in the IIA occlusion, the figures were 10 (42%) and 7 (29%), respectively. No patient in the IBD group developed buttock claudication compared to 8 (57%, p<.0001) in the IIA occlusion group; 1 (4%) patient developed bowel ischemia on both groups, with 1 in the IIA occlusion group needing resection. The median follow-up duration was 17 months (interquartile range 2–39) for the IBD group, with a primary patency of 60±14% at 3 years that went up to 92±8% with reinterventions (8 reinterventions in 6 patients). When the first 90 days were disregarded, there were no differences in survival between the groups. Conclusion: IBD is a valid alternative for maintaining the pelvic circulation for endovascular aortic aneurysm repair of ruptured aortoiliac aneurysms. The technical success and midterm outcomes are very satisfactory but require patient selection particularly regarding hemodynamic stability. The reintervention rate is considerable, mandating continuous follow-up. Clinical Impact: This multicenter study demonstrates that ruptured aortoiliac aneurysms do not necessarily require mandatory occlusion of hypogastric arteries. Iliac branch devices are shown to be a valid alternative in highly selected cases, with good midterm results, even if reinterventions are required in a significant proportion of patients. [ABSTRACT FROM AUTHOR]

Published
2024
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28. Outcomes of Off the Shelf Outer Branched Versus Inner Branched Endografts in the Treatment of Thoraco-abdominal Aortic Aneurysm in the B.R.I.O. (BRanched Inner – Outer) Study Group

Author

Piazza, Michele, primary, Squizzato, Francesco, additional, Pratesi, Giovanni, additional, Parlani, Gianbattista, additional, Simonte, Gioele, additional, Giudice, Rocco, additional, Mansour, Wassim, additional, Veraldi, Gian Franco, additional, Gennai, Stefano, additional, Antonello, Michele, additional, Spertino, Andrea, additional, Grego, Franco, additional, Di Gregorio, Sara, additional, Lenti, Massimo, additional, Isernia, Giacomo, additional, Ferrer, Ciro, additional, Piffaretti, Gabriele, additional, Mauri, Francesca, additional, Mezzetto, Luca, additional, Mastrorilli, Davide, additional, Silingardi, Roberto, additional, Leone, Nicola, additional, Tshomba, Yamume, additional, Donati, Tommaso, additional, Sica, Simona, additional, Tinelli, Giovanni, additional, Pulli, Raffaele, additional, Fargion, Aaron, additional, Pratesi, Carlo, additional, Di Marzo, Luca, additional, Di Girolamo, Alessia, additional, Orticelli, Assunta, additional, Mechelagnoli, Stefano, additional, Chisci, Emiliano, additional, Fazzini, Stefano, additional, Oddi, Fabio Massimo, additional, and Ippoliti, Arnaldo, additional

Published
2024
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30. Second asymptomatic carotid surgery trial (ACST-2): a randomised comparison of carotid artery stenting versus carotid endarterectomy

Author

Halliday, Alison, Bulbulia, Richard, Bonati, Leo H, Peto, Richard, Pan, Hongchao, Potter, John, Henning Eckstein, Hans, Farrell, Barbara, Flather, Marcus, Mansfield, Averil, Mihaylova, Boby, Rahimi, Kazim, Simpson, David, Thomas, Dafydd, Sandercock, Peter, Gray, Richard, Molyneux, Andrew, Shearman, Cliff P, Rothwell, Peter, Belli, Anna, Herrington, Will, Judge, Parminder, Leopold, Peter, Mafham, Marion, Gough, Michael, Cao, Piergiorgio, MacDonald, Sumaira, Bari, Vasha, Berry, Clive, Bradshaw, S, Brudlo, Wojciech, Clarke, Alison, Chester, Johanna, Cox, Robin, Cradduck-Bamford, Andrea, Fathers, Susan, Gaba, Kamran, Gray, Mo, Hayter, Elizabeth, Holliday, Constance, Kurien, Rijo, Lay, Michael, le Conte, Steffi, McManus, Jessica, Madgwick, Zahra, Morris, Dylan, Munday, Andrew, Pickworth, Sandra, Ostasz, Wiktor, Poorthuis, Michiel, Richards, Sue, Teixeira, Louisa, Tochlin, Sergey, Tully, Lynda, Wallis, Carol, Willet, Monique, Young, Alan, Casana, Renato, Malloggi, Chiara, Odero Jr, Andrea, Silani, Vincenzo, Parati, Gianfranco, Malchiodi, Giuseppe, Malferrari, Giovanni, Strozzi, Francesco, Tusini, Nicola, Vecchiati, Enrico, Coppi, Gioacchino, Lauricella, Antonio, Moratto, Roberto, Silingardi, Roberto, Veronesi, Jessica, Zini, Andrea, Ferrero, Emanuele, Ferri, Michelangelo, Gaggiano, Andrea, Labate, Carmelo, Nessi, Franco, Psacharopulo, Daniele, Viazzo, Andrea, Malacrida, Giovanni, Mazzaccaro, Daniela, Meola, Giovanni, Modafferi, Alfredo, Nano, Giovanni, Occhiuto, Maria Teresa, Righini, Paolo, Stegher, Silvia, Chiarandini, Stefano, Griselli, Filippo, Lepidi, Sandro, Pozzi Mucelli, Fabio, Naccarato, Marcello, D'Oria, Mario, Ziani, Barbara, Stella, Andrea, Dieng, Mortalla, Faggioli, Gianluca, Gargiulo, Mauro, Palermo, Sergio, Pini, Rodolfo, Puddu, Giovanni Maria, Vacirca, Andrea, Angiletta, Domenico, Desantis, Claudio, Marinazzo, Davide, Mastrangelo, Giovanni, Regina, Guido, Pulli, Raffaele, Bianchi, Paolo, Cireni, Lea, Coppi, Elisabetta, Pizzirusso, Rocco, Scalise, Filippo, Sorropago, Giovanni, Tolva, Valerio, Caso, Valeria, Cieri, Enrico, DeRango, Paola, Farchioni, Luca, Isernia, Giacomo, Lenti, Massimo, Parlani, Gian Battista, Pupo, Guglielmo, Pula, Grazia, Simonte, Gioele, Verzini, Fabio, Carimati, Federico, Delodovici, Maria Luisa, Fontana, Federico, Piffaretti, Gabriele, Tozzi, Matteo, Civilini, Efrem, Poletto, Giorgio, Reimers, Bernhard, Praquin, Barbara, Ronchey, Sonia, Capoccia, Laura, Mansour, Wassim, Sbarigia, Enrico, Speziale, Francesco, Sirignano, Pasqualino, Toni, Danilo, Galeotti, Roberto, Gasbarro, Vincenzo, Mascoli, Francesco, Rocca, Tiberio, Tsolaki, Elpiniki, Bernardini, Giulia, DeMarco, Ester, Giaquinta, Alessia, Patti, Francesco, Veroux, Massimiliano, Veroux, Pierfrancesco, Virgilio, Carla, Mangialardi, Nicola, Orrico, Matteo, Di Lazzaro, Vincenzo, Montelione, Nunzio, Spinelli, Francesco, Stilo, Francesco, Cernetti, Carlo, Irsara, Sandro, Maccarrone, Giuseppe, Tonello, Diego, Visonà, Adriana, Zalunardo, Beniamino, Chisci, Emiliano, Michelagnoli, Stefano, Troisi, Nicola, Masato, Maela, Dei Negri, Massimo, Pacchioni, Andrea, Saccà, Salvatore, Amatucci, Giovanni, Cannizzaro, Alfredo, Accrocca, Federico, Ambrogi, Cesare, Barbazza, Renzo, Marcucci, Giustino, Siani, Andrea, Bajardi, Guido, Savettieri, Giovanni, Argentieri, Angelo, Corbetta, Riccardo, Odero, Attilio, Quaretti, Pietro, Thyrion, Federico Z, Cappelli, Alessandro, Benevento, Domenico, De Donato, Gianmarco, Mele, Maria Agnese, Palasciano, Giancarlo, Pieragalli, Daniela, Rossi, Alessandro, Setacci, Carlo, Setacci, Francesco, Palombo, Domenico, Perfumo, Maria Cecilia, Martelli, Edoardo, Paolucci, Aldo, Trimarchi, Santi, Grassi, Viviana, Grimaldi, Luigi, La Rosa, Giuliana, Mirabella, Domenico, Scialabba, Matteo, Sichel, Leonildo, D'Angelo, Costantino L, Fadda, Gian Franco, Kasemi, Holta, Marino, Mario, Burzotta, Francesco, Codispoti, Francesco Alberto, Ferrante, Angela, Tinelli, Giovanni, Tshomba, Yamume, Vincenzoni, Claudio, Amis, Deborah, Anderson, Dawn, Catterson, Martin, Clarke, Mike, Davis, Michelle, Dixit, Anand, Dyker, Alexander, Ford, Gary, Jackson, Ralph, Kappadath, Sreevalsan, Lambert, David, Lees, Tim, Louw, Stephen, McCaslin, James, Parr, Noala, Robson, Rebecca, Stansby, Gerard, Wales, Lucy, Wealleans, Vera, Wilson, Lesley, Wyatt, Michael, Baht, Hardeep, Balogun, Ibrahim, Burger, Ilse, Cosier, Tracy, Cowie, Linda, Gunathilagan, Gunaratnam, Hargroves, David, Insall, Robert, Jones, Sally, Rudenko, Hannah, Schumacher, Natasha, Senaratne, Jawaharlal, Thomas, George, Thomson, Audrey, Webb, Tom, Brown, Ellen, Esisi, Bernard, Mehrzad, Ali, MacSweeney, Shane, McConachie, Norman, Southam, Alison, Sunman, Wayne, Abdul-Hamiq, Ahmed, Bryce, Jenny, Chetter, Ian, Ettles, Duncan, Lakshminarayan, Raghuram, Mitchelson, Kim, Rhymes, Christopher, Robinson, Graham, Scott, Paul, Vickers, Alison, Ashleigh, Ray, Butterfield, Stephen, Gamble, Ed, Ghosh, Jonathan, McCollum, Charles N, Welch, Mark, Welsh, Sarah, Wolowczyk, Leszek, Donnelly, Mary, D'Souza, Stephen, Egun, Anselm A, Gregary, Bindu, Joseph, Thomas, Kelly, Christine, Punekar, Shuja, Rahi, M Asad, Raj, Sonia, Seriki, Dare, Thomson, George, Brown, James, Durairajan, Ragunath, Grunwald, Iris, Guyler, Paul, Harman, Paula, Jakeways, Matthew, Khuoge, Christopher, Kundu, Ashish, Loganathan, Thayalini, Menon, Nisha, Prabakaran, Raji O, Sinha, Devesh, Thompson, Vicky, Tysoe, Sharon, Briley, Dennis, Darby, Chris, Hands, Linda, Howard, Dominic, Kuker, Wilhelm, Schulz, Ursula, Teal, Rachel, Barer, David, Brown, Andrew, Crawford, Susan, Dunlop, Paul, Krishnamurthy, Ramesh, Majmudar, Nikhil, Mitchell, Duncan, Myint, Min P, O'Brien, Richard, O'Connell, Janice, Sattar, Naweed, Vetrivel, Shanmugam, Beard, Jonathan, Cleveland, Trevor, Gaines, Peter, Humphreys, John, Jenkins, Alison, King, Craig, Kusuma, Daniel, Lindert, Ralph, Lonsdale, Robbie, Nair, Raj, Nawaz, Shah, Okhuoya, Faith, Turner, Douglas, Venables, Graham, Dorman, Paul, Hughes, Andrea, Jones, Deborah, Mendelow, David, Rodgers, Helen, Raudoniitis, Aidas, Enevoldson, Peter, Nahser, Hans, O'Brien, Imelda, Torella, Francesco, Watling, Dave, White, Richard, Brown, Pauline, Dutta, Dipankar, Emerson, Lorraine, Hilltout, Paula, Kulkarni, Sachin, Morrison, Jackie, Poskitt, Keith, Slim, Fiona, Smith, Sarah, Tyler, Amanda, Waldron, Joanne, Whyman, Mark, Bajoriene, Milda, Baker, Lucy, Colston, Amanda, Eliot-Jones, Bekky, Gramizadeh, Gita, Lewis-Clarke, Catherine, McCafferty, Laura, Oliver, Deborah, Palmer, Debbie, Patil, Abhijeet, Pegler, Suzannah, Ramadurai, Gopi, Roberts, Aisling, Sargent, Tracey, Siddegowda, Shivaprasad, Singh-Ranger, Ravi, Williams, Akintunde, Williams, Lucy, Windebank, Steve, Zuromskis, Tadas, Alwis, Lanka, Angus, Jane, Asokanathan, Asaipillai, Fornolles, Caroline, Hardy, Diana, Hunte, Sophy, Justin, Frances, Phiri, Duke, Mitabouana-Kibou, Marie, Sekaran, Lakshmanan, Sethuraman, Sakthivel, Tate, Margaret L, Akyea-Mensah, Joyce, Ball, Stephen, Chrisopoulou, Angela, Keene, Elizabeth, Phair, Alison, Rogers, Steven, Smyth, John V, Bicknell, Colin, Chataway, Jeremy, Cheshire, Nicholas, Clifton, Andrew, Eley, Caroline, Gibbs, Richard, Hamady, Mohammad, Hazel, Beth, James, Alex, Jenkins, Michael, Khanom, Nyma, Lacey, Austin, Mireskandari, Maz, O'Reilly, Joanna, Pereira, Antony, Sachs, Tina, Wolfe, John, Davey, Philip, Rogers, Gill, Smith, Gemma, Tervit, Gareth, Nichol, Ian, Parry, Andrew, Young, Gavin, Ashley, Simon, Barwell, James, Dix, Francis, Nor, Azlisham M, Parry, Chris, Birt, Angela, Davies, Paul, George, Jim, Graham, Anne, Jonker, Leon, Kelsall, Nicci, Potts, Caroline, Wilson, Toni, Crinnion, Jamie, Cuenoud, Larissa, Aleksic, Nikola, Babic, Srdan, Ilijevski, Nenad, Radak, Đorde, Sagic, Dragan, Tanaskovic, Slobodan, Colic, Momcilo, Cvetic, Vladimir, Davidovic, Lazar, Jovanovic, Dejana R, Koncar, Igor, Mutavdžic, Perica, Sladojevic, Miloš, Tomic, Ivan, Debus, Eike S, Grzyska, Ulrich, Otto, Dagmar, Thomalla, Götz, Barlinn, Jessica, Gerber, Johannes, Haase, Kathrin, Hartmann, Christian, Ludwig, Stefan, Pütz, Volker, Reeps, Christian, Schmidt, Christine, Weiss, Norbert, Werth, Sebastian, Winzer, Simon, Gemper, Janine, Günther, Albrecht, Heiling, Bianka, Jochmann, Elisabeth, Karvouniari, Panagiota, Klingner, Carsten, Mayer, Thomas, Schubert, Julia, Schulze-Hartung, Friederike, Zanow, Jürgen, Bausback, Yvonne, Borger, Franka, Botsios, Spiridon, Branzan, Daniela, Bräunlich, Sven, Hölzer, Henryk, Lenzer, Janin, Piorkowski, Christopher, Richter, Nadine, Schuster, Johannes, Scheinert, Dierk, Schmidt, Andrej, Staab, Holger, Ulrich, Matthias, Werner, Martin, Berger, Hermann, Biró, Gábor, Eckstein, Hans-Henning, Kallmayer, Michael, Kreiser, Kornelia, Zimmermann, Alexander, Berekoven, Bärbel, Frerker, Klaus, Gordon, Vera, Torsello, Giovanni, Arnold, Sebastian, Dienel, Cora, Storck, Martin, Biermaier, Bernhard, Gissler, Hans Martin, Klötzsch, Christof, Pfeiffer, Tomas, Schneider, Ralph, Söhl, Leander, Wennrich, Michael, Alonso, Angelika, Keese, Michael, Groden, Christoph, Cöster, Andreas, Engelhardt, Andreas, Ratusinski, Christoph-Maria, Berg, Bengt, Delle, Martin, Formgren, Johan, Gillgren, Peter, Jarl, Lotta, Kall, Torbjörn B, Konrad, Peter, Nyman, Niklas, Skiöldebrand, Claes, Steuer, Johnny, Takolander, Rabbe, Malmstedt, Jonas, Acosta, Stefan, Björses, Katarina, Brandt, Kerstin, Dias, Nuno, Gottsäter, Anders, Holst, Jan, Kristmundsson, Thorarinn, Kühme, Tobias, Kölbel, Tilo, Lindblad, Bengt, Lindh, Mats, Malina, Martin, Ohrlander, Tomas, Resch, Tim, Rönnle, Viola, Sonesson, Björn, Warvsten, Margareta, Zdanowski, Zbigniew, Campbell, Erik, Kjellin, Per, Lindgren, Hans, Nyberg, Johan, Petersen, Björn, Plate, Gunnar, Pärsson, Håkan, Qvarfordt, Peter, Ignatenko, Pavel, Karpenko, Andrey, Starodubtsev, Vladimir, Chernyavsky, Mikhail A, Golovkova, Maria S, Komakha, Boris B, Zherdev, Nikolay N, Belyasnik, Andrey, Chechulov, Pavel, Kandyba, Dmitry, Stepanishchev, Igor, Csobay-Novák, Csaba, Dósa, Edit, Entz, László, Nemes, Balázs, Szeberin, Zoltán, Barzó, Pál, Bodosi, Mihaly, Fákó, Eniko, Fülöp, Béla, Németh, Tamás, Pazdernyik, Szilárd, Skoba, Krisztina, Vörös, Erika, Chatzinikou, Eleni, Giannoukas, Athanasios, Karathanos, Christos, Koutsias, Stylianos, Kouvelos, Georgios, Matsagkas, Miltiadis, Ralli, Styliani, Rountas, Christos, Rousas, Nikolaos, Spanos, Konstantinos, Brountzos, Elias, Kakisis, John D, Lazaris, Andreas, Moulakakis, Konstantinos G, Stefanis, Leonidas, Tsivgoulis, Georgios, Vasdekis, Spyros, Antonopoulos, Constantine N, Bellenis, Ion, Maras, Dimitrios, Polydorou, Antonios, Polydorou, Victoria, Tavernarakis, Antonios, Ioannou, Nikolaos, Terzoudi, Maria, Lazarides, Miltos, Mantatzis, Michalis, Vadikolias, Kostas, Dzieciuchowicz, Lukasz, Gabriel, Marcin, Krasinski, Zbigniew, Oszkinis, Grzegorz, Pukacki, Fryderyk, Slowinski, Maciej, Stanišic, Michal-Goran, Staniszewski, Ryszard, Tomczak, Jolanta, Zielinski, Maciej, Myrcha, Piotr, Rózanski, Dorota, Drelichowski, Stanislaw, Iwanowski, Wojciech, Koncewicz, Katarzyna, Bialek, Pawel, Biejat, Zbigniew, Czepel, Wojciech, Czlonkowska, Anna, Dowzenko, Anatol, Jedrzejewska, Julia, Kobayashi, Adam, Leszczynski, Jerzy, Malek, Andrzej, Polanski, Jerzy, Proczka, Robert, Skorski, Maciej, Szostek, Mieczyslaw, Andziak, Piotr, Dratwicki, Maciej, Gil, Robert, Nowicki, Miroslaw, Pniewski, Jaroslaw, Rzezak, Jaroslaw, Seweryniak, Piotr, Dabek, Pawel, Juszynski, Michal, Madycki, Grzegorz, Pacewski, Bartosz, Raciborski, Witold, Slowinski, Piotr, Staszkiewicz, Walerian, Bombic, Martin, Chlouba, Vladimír, Fiedler, Jirí, Hes, Karel, Koštál, Petr, Sova, Jindrich, Kríž, Zdenek, Prívara, Mojmír, Reif, Michal, Staffa, Robert, Vlachovský, Robert, Vojtíšek, Bohuslav, Hrbác, Tomáš, Kuliha, Martin, Procházka, Václav, Roubec, Martin, Školoudík, David, Netuka, David, Šteklácová, Anna, Beneš III, Vladimír, Buchvald, Pavel, Endrych, Ladislav, Šercl, Miroslav, Campos Jr, Walter, Casella, Ivan B, de Luccia, Nelson, Estenssoro, André E V, Presti, Calógero, Puech-Leão, Pedro, Neves, Celso R B, da Silva, Erasmo S, Sitrângulo Jr, Cid J, Monteiro, José A T, Tinone, Gisela, Bellini Dalio, Marcelo, Joviliano, Edwaldo E, Pontes Neto, Octávio M, Serra Ribeiro, Mauricio, Cras, Patrick, Hendriks, Jeroen M H, Hoppenbrouwers, Mieke, Lauwers, Patrick, Loos, Caroline, Yperzeele, Laetitia, Geenens, Mia, Hemelsoet, Dimitri, van Herzeele, Isabelle, Vermassen, Frank, Astarci, Parla, Hammer, Frank, Lacroix, Valérie, Peeters, André, Verhelst, Robert, Cirelli, Silvana, Dormal, Pol, Grimonprez, Annelies, Lambrecht, Bart, Lerut, Philipe, Thues, Eddy, De Koster, Guy, Desiron, Quentin, Maertens de Noordhout, Alain, Malmendier, Danielle, Massoz, Mireille, Saad, Georges, Bosiers, Marc, Callaert, Joren, Deloose, Koen, Blanco Cañibano, Estrella, García Fresnillo, Beatriz, Guerra Requena, Mercedes, Morata Barrado, Pilar C, Muela Méndez, Miguel, Yusta Izquierdo, Antonio, Aparici Robles, Fernando, Blanes Orti, Paula, García Dominguez, Luis, Martínez López, Rafael, Miralles Hernández, Manuel, Tembl Ferrairo, José I, Chamorro, Ángel, Macho, Juan, Obach, Víctor, Riambau, Vincent, San Román, Luis, Ahlhelm, Frank J, Blackham, Kristine, Engelter, Stefan, Eugster, Thomas, Gensicke, Henrik, Gürke, Lorenz, Lyrer, Philippe, Mariani, Luigi, Maurer, Marina, Mujagic, Edin, Müller, Mandy, Psychogios, Marios, Stierli, Peter, Stippich, Christoph, Traenka, Christopher, Wolff, Thomas, Wagner, Benjamin, Wiegert, Martina M, Clarke, Sandra, Diepers, Michael, Gröchenig, Ernst, Gruber, Philipp, Isaak, Andrej, Kahles, Timo, Marti, Regula, Nedeltchev, Krassen, Remonda, Luca, Tissira, Nadir, Valença Falcão, Martina, de Borst, Gert J, Lo, Rob H, Moll, Frans L, Toorop, Raechel, van der Worp, Bart H, Vonken, Evert J, Kappelle, Jaap L, Jahrome, Ommid, Vos, Floris, Schuiling, Wouter, van Overhagen, Hendrik, Keunen, Rudolf W M, Knippenberg, Bob, Wever, Jan J, Lardenoije, Jan W, Reijnen, Michel, Smeets, Luuk, van Sterkenburg, Steven, Fraedrich, Gustav, Gizewski, Elke, Gruber, Ingrid, Knoflach, Michael, Kiechl, Stefan, Rantner, Barbara, Abdulamit, Timur, Bergeron, Patrice, Padovani, Raymond, Trastour, Jean-Christophe, Cardon, Jean-Marie, Le Gallou-Wittenberg, Anne, Allaire, Eric, Becquemin, Jean-Pierre, Cochennec-Paliwoda, Frédéric, Desgranges, Pascal, Hosseini, Hassan, Kobeiter, Hicham, Marzelle, Jean, Almekhlafi, Mohammed A, Bal, Simerpreet, Barber, Phillip A, Coutts, Shelagh B, Demchuk, Andrew M, Eesa, Muneer, Gillies, Michelle, Goyal, Mayank, Hill, Michael D, Hudon, Mark E, Jambula, Anitha, Kenney, Carol, Klein, Gary, McClelland, Marie, Mitha, Alim, Menon, Bijoy K, Morrish, William F, Peters, Steven, Ryckborst, Karla J, Samis, Greg, Save, Supriya, Smith, Eric E, Stys, Peter, Subramaniam, Suresh, Sutherland, Garnette R, Watson, Tim, Wong, John H, Zimmel, L, Flis, Vojko, Matela, Jože, Miksic, Kazimir, Milotic, Franko, Mrdja, Božidar, Stirn, Barbara, Tetickovic, Erih, Gasparini, Mladen, Grad, Anton, Kompara, Ingrid, Miloševic, Zoren, Palmiste, Veronika, Toomsoo, Toomas, Aidashova, Balzhan, Kospanov, Nursultan, Lyssenko, Roman, Mussagaliev, Daulet, Beyar, Rafi, Hoffman, Aaron, Karram, Tony, Kerner, Arthur, Nikolsky, Eugenia, Nitecki, Samy, Andonova, Silva, Bachvarov, Chavdar, Petrov, Vesko, Cvjetko, Ivan, Vidjak, Vinko, Halužan, Damir, Petrunic, Mladen, Liu, Bao, Liu, Chang-Wei, Bartko, Daniel, Beno, Peter, Rusnák, František, Zelenák, Kamil, Ezura, Masayuki, Inoue, Takashi, Kimura, Naoto, Kondo, Ryushi, Matsumoto, Yasushi, Shimizu, Hiroaki, Endo, Hidenori, Furui, Eisuke, Bakke, Søren, Krohg-Sørensen, Kristen, Nome, Terje, Skjelland, Mona, Tennøe, Bjørn, Albuquerque e Castro, João, Alves, Gonçalo, Bastos Gonçalves, Frederico, de Aragão Morais, José, Garcia, Ana C, Valentim, Hugo, Vasconcelos, Leonor, Belcastro, Fernando, Cura, Fernando, Zaefferer, Patricio, Abd-Allah, Foad, Eldessoki, Mohamed H, Heshmat Kassem, Hussein, Soliman Gharieb, Haytham, Colgan, Mary P, Haider, Syed N, Harbison, Joe, Madhavan, Prakash, Moore, Dermot, Shanik, Gregor, Kazan, Viviane, Nazzal, Munier, and Ramsey-Williams, Vicki

Published
2021
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32. Endograft Thrombosis as an Indication for Open Conversion after Endovascular Aneurysm Repair in a Multicenter Experience over 25 Years

Author

Fornasari, Anna, Perini, Paolo, Gargiulo, Mauro, Silingardi, Roberto, Michelagnoli, Stefano, Bonardelli, Stefano, Bellosta, Raffaello, Freyrie, Antonio, Mersanne, Arianna, Gerosa, Cecilia, Mariani, Erica, Faggioli, Gianluca, Ancetti, Stefano, Migliari, Mattia, Gennai, Stefano, Chisci, Emiliano, Melloni, Andrea, Attisani, Luca, Piffaretti, Gabriele, Mauri, Francesca, Troisi, Nicola, Berchiolli, Raffaella, Fanelli, Mara, Paciaroni, Elisa, and Marchetti, Federica

Abstract

To describe the outcomes of aortic endograft thrombosis (AET) as an indication for open conversion (OC) after endovascular aortic aneurysm repair (EVAR) in a multicenter experience.

Published
2024
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33. Twenty-Five Year Multicentre Experience of Explantation of Infected Abdominal Aortic Endografts.

Author

Perini, Paolo, Gargiulo, Mauro, Silingardi, Roberto, Bonardelli, Stefano, Bellosta, Raffaello, Piffaretti, Gabriele, Michelagnoli, Stefano, Ferrari, Mauro, Turicchia, Giorgio Ubaldo, Freyrie, Antonio, Fornasari, Anna, Mariani, Erica, Faggioli, GianLuca, Spath, Paolo, Migliari, Mattia, Gennai, Stefano, Paro, Barbara, Baggi, Paolo, Attisani, Luca, and Pegorer, Matteo

Subjects
AORTA surgery, KIDNEY failure, PROSTHESIS-related infections, ENDOVASCULAR aneurysm repair, HOSPITAL care, RESPIRATORY insufficiency, BLOOD vessel prosthesis, RETROSPECTIVE studies, TREATMENT effectiveness, HOSPITAL mortality, DESCRIPTIVE statistics, VASCULAR surgery, SURGICAL complications, LOG-rank test, ABDOMINAL aortic aneurysms, RESEARCH, HEALTH facilities, PLASTIC surgery, PATIENT aftercare, TIME, DISEASE risk factors, SYMPTOMS
Abstract

We report a multicenter experience of open conversions (OC) for aortic endograft infections (AEI). We retrospectively analyzed all patients who underwent OC for AEI after endovascular aneurysm repair (EVAR), from 1997 to 2021 in 12 Italian centers. The endpoints were as follows: mortality (30-days, in-hospital), major postoperative complications. Follow-up data included: survival, aortic-related complications, infection persistence or reoccurrence. Fifty-eight patients (mean age: 73.8 ± 6.6 years) were included. Median time from EVAR to OC was 14 months (interquartile range 7–45). Thirty-five patients (60.3%) were symptomatic at presentation. Aortic reconstruction was anatomic in 32 patients (55.2%), extra-anatomic in 26 (44.8%). Thirty-day mortality was 31% (18/58). Six additional patients died after 30 days during the same hospitalization (in-hospital mortality: 41.4%). Most common post-operative complications included respiratory failure (38.6%) and renal insufficiency (35.1%). During 28.1 ± 4 months follow-up, 4 aneurysm-related deaths were recorded. Infection re-occurred in 29.4% of the patients. Estimated survival was 50% at 1 year, and 30% at 5 years, and was significantly lower for patients who underwent extra-anatomic reconstructions (37 vs 61% at 1 year, 16 vs 45% at 5 years; log-rank P =.021). OC for AEI is associated with high early mortality. The poor mid-term survival is influenced by aortic complications and infection re-occurrence. [ABSTRACT FROM AUTHOR]

Published
2025
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36. Learning Curve and Long-Term Outcomes of Thoracic Endovascular Repair With the Relay Stent-Graft.

Author

Gennai, Stefano, Leone, Nicola, Bartolotti, Luigi A. M., Andreoli, Francesco, Pizzarelli, Ginevra, and Silingardi, Roberto

Abstract

Purpose: To define the learning curve of a widely employed stent-graft for thoracic endovascular repair (TEVAR) by analyzing procedural variables and their impact on long-term outcomes. Materials and Methods: Standard TEVARs for each major aortic thoracic disease were included excluding procedures using thoracoabdominal, arch fenestrated/branched devices and/or chimneys. The primary outcome was the learning curve analysis using the cumulative sum chart method. The secondary outcomes, presented as early (Q1–Q2) versus latest (Q3–Q4) quartiles of experience, were 30-day major adverse events (MAEs); procedural details (additional maneuvers, operative and fluoroscopy time, and contrast volume); 30-day clinical success; endoleak; aorta-related reintervention; and overall and aorta-related survival. Results: Between November 2005 and September 2021, 220 consecutive TEVAR procedures involving the Relay endograft (Terumo Aortic, Sunrise, FL, USA) were performed and included in the present analysis. The mean follow-up was 4.5 ± 3.9 years. The learning curve was reached after 10 patients. Secondary outcomes improved significantly over experience. Thirty-day MAE occurrence was 14.5% versus 11.8% (p=0.550). Additional maneuvers (p=0.009), access-vessel additional maneuvers (p=0.010), operative time (p=0.004), Relay Plus (p=0.001), and implantation of multiple stent-grafts (p=0.034) were independent risk markers for MAEs. Operative time (125.9 ± 66.7 vs 86.7 ± 48.5 minutes, p<0.001), contrast volume (185.4 ± 112.8 vs 140.5 ± 88.2 mL, p=0.003), and fluoroscopy time (12.4 ± 12.7 vs 8.8 ± 7.5 minutes, p=0.017) decreased significantly. Late endoleak occurrence was 19.5% with a nonsignificant reduction (21.8% vs 17.3%, p=0.395). Fluoroscopy time (hazard ratio [HR]=1.0; 95% confidence interval [CI]=1.0–1.1; p=0.008), contrast volume (HR=1.0; 95% CI=1.0–1.1; p=0.018), and type III aortic arch (HR=3.3; 95% CI=1.7–6.4; p<0.001) were independent risk markers for endoleak. Fluoroscopy time (HR=1.0; 95% CI=1.0–1.1; p=0.032) and type III aortic arch (HR=3.6; 95% CI=1.7–7.4; p=0.001) confirmed their significant association in a multivariable analysis. Conclusion: In a high-volume center with a consistent previous endovascular experience, the Relay graft presented satisfactory long-term results with a short learning curve supporting its reliability. Clinical Impact: The manuscript addresses the understanding of how many TEVAR procedures with a currently implanted device have been required to reach the learning curve for an endovascular skilled center. Our TEVAR experience with the Relay stent-graft (Terumo Aortic) demonstrated that ten implantations were required to achieve the device-related learning curve. The fifteen-year analyzed period showed that intraoperative learning-related variables were associated with long-term clinical outcomes and both improved over time. The Relay stent-graft presented satisfactory long-term results along with a short learning curve in a high-volume endovascular center supporting its ongoing implantation. [ABSTRACT FROM AUTHOR]

Published
2024
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37. Twenty-two Year Multicentre Experience of Late Open Conversions after Endovascular Abdominal Aneurysm Repair

Author

Mariani, Erica, Faggioli, GianLuca, Gallitto, Enrico, Migliari, Mattia, Gennai, Stefano, Paro, Barbara, Baggi, Paolo, Attisani, Luca, Pegorer, Matteo, Tasselli, Sebastiano, Wassermann, Valentina, Chisci, Emiliano, Troisi, Nicola, Fontana, Antonio, Strozzi, Francesco, Scabini, Matteo, Mosso, Federico, Gessaroli, Massimiliano, Leone, Michele, Masi, Giancarlo, Turicchia, Giorgio Ubaldo, Perini, Paolo, Gargiulo, Mauro, Silingardi, Roberto, Bonardelli, Stefano, Bellosta, Raffaello, Bonvini, Stefano, Michelagnoli, Stefano, Tusini, Nicola, Capelli, Patrizio, and Freyrie, Antonio

Published
2020
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40. Comparison Of Self- and Balloon-Expandable Bridging Stent-Grafts in Branched Endovascular Aortic Repair (COVIBRI study)

Author

Migliari, Mattia, primary, Leone, Nicola, additional, Veraldi, Gian Franco, additional, Simonte, Gioele, additional, Silingardi, Roberto, additional, Resch, Timothy, additional, Gennai, Stefano, additional, Bartolotti, Luigi Alberto Maria, additional, Leonardi, Lorenzo, additional, Mezzetto, Luca, additional, Grosso, Lorenzo, additional, and Isernia, Giacomo, additional

Published
2023
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45. Comparison of bridging stent grafts in branched endovascular aortic repair.

Author

Migliari, Mattia, Leone, Nicola, Veraldi, Gian Franco, Simonte, Gioele, Silingardi, Roberto, Resch, Timothy, and Gennai, Stefano

Abstract

Endovascular treatment of thoracoabdominal aortic aneurysms has become common, with satisfactory results. Nevertheless, long-term durability remains an issue mainly because of target visceral vessel (TVV) instability. Currently, no covered stent has been approved as a bridging stent graft (BSG), demanding continuous research on this topic. This was a multicenter observational retrospective cohort study comparing the midterm results of the Bard Covera Plus and Gore VBX as BSGs during branched endovascular aneurysm repair. The primary outcome was the comparison of the target vessel instability between the two groups. Primary patency, freedom from branch-related type I and III endoleaks and reintervention, and technical and clinical success were considered secondary outcomes. Logistic regression analysis was used to assess the association between selected baseline factors and TVV instability. TVV instability during follow-up was then evaluated using the Kaplan-Meier cumulative function. Three hundred forty-five TVVs in 106 patients were considered suitable for the analysis. Two hundred twenty vessels were stented with the Covera stent graft (64%) and 125 with VBX (36%). Two hundred ninety-nine TVVs received a single BSG, 45 two BSGs, and only 1 three BSGs. Bare metal stent relining was required in 36% of TVVs, mostly in the Covera group (89 [41%] vs 36 [29%]) (P =.030). The primary technical success rate was 96% (331/345), and the assisted primary technical success rate was 99% (342/345). The TVV instability rate within 30 days was 2% (one Covera and five VBX; P =.015). Three BSG occlusions (one Covera and two VBX) and three type Ic endoleaks (three VBX) were detected. The median follow-up was 13.9 months (range, 5.8-25.5 months). Sixteen TVV instabilities were detected during the follow-up. Twelve BSG occlusions (six Covera and six VBX), three type Ic endoleaks (one Covera and two VBX), and one type IIIc endoleak (VBX). The overall target vessel instability rate was 5% (16/342). TVV instability was associated with the use of Gore VBX in the univariable logistic regression (odds ratio, 3.0; 95% confidence interval, 1.1-8.0; P =.027). Aneurysm rupture and aneurysm diameter were also associated with TVV instability in the univariable analysis (P =.002 and P =.008, respectively). The only factor predisposing to TVV instability in the multivariable logistic regression analysis was the use of Gore VBX as a BSG (odds ratio, 2.9; 95% confidence interval, 1.0-8.0; P =.043). Kaplan-Meier analysis showed a significantly higher risk of TVV instability in the VBX group (P <.001). Overall midterm outcomes in this cohort were satisfactory. Patency rates were similar between the two stents. Nevertheless, VBX seems to be associated with worse TVV instability. These results may be correlated with a higher incidence of type Ic endoleaks, which require an extensive learning curve for correct stent selection and deployment. [ABSTRACT FROM AUTHOR]

Published
2024
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48. Bypass vs endovascular treatment for occluded femoro-popliteal stents in patients with critical limb-threatening ischemia

Author

D’Oria, Mario, primary, Berchiolli, Raffaella, additional, Gargiulo, Mauro, additional, Antonello, Michele, additional, Pratesi, Giovanni, additional, Michelagnoli, Stefano, additional, Silingardi, Roberto, additional, Isernia, Giacomo, additional, Veraldi, Gian Franco, additional, Tinelli, Giovanni, additional, Giudice, Rocco, additional, Ippoliti, Arnaldo, additional, Cappiello, Pierluigi, additional, Martelli, Massimiliano, additional, Lepidi, Sandro, additional, Troisi, Nicola, additional, Abualhin, Mohammad, additional, Andreini, Marco, additional, Bastianon, Martina, additional, Calvagna, Cristiano, additional, Colacchio, Chiara, additional, D'Andrea, Alessia, additional, Esposito, Andrea, additional, Caneva, Patrizia Dalla, additional, Fazzini, Stefano, additional, Ferrer, Ciro, additional, Gallitto, Enrico, additional, Gennai, Stefano, additional, Giordano, Antonio Nicola, additional, Leone, Nicola, additional, Mastrorilli, Davide, additional, Melani, Caterina, additional, Mena Vera, Jorge Miguel, additional, Mezzetto, Luca, additional, Parlani, Gianbattista, additional, Scarati, Valentina, additional, Sica, Simona, additional, Simonte, Gioele, additional, Squizzato, Francesco, additional, Spath, Paolo, additional, Thsomba, Yamume, additional, Visciglia, Elvira, additional, and Zanetti, Elisa, additional

Published
2023
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49. Editor's Choice – Early Outcomes of a Novel Off the Shelf Preloaded Inner Branch Endograft for the Treatment of Complex Aortic Pathologies in the ItaliaN Branched Registry of E-nside EnDograft (INBREED)

Author

Piazza, Michele, primary, Squizzato, Francesco, additional, Pratesi, Giovanni, additional, Tshomba, Yamume, additional, Gaggiano, Andrea, additional, Gatta, Emanuele, additional, Simonte, Gioele, additional, Piffaretti, Gabriele, additional, Frigatti, Paolo, additional, Veraldi, Gian Franco, additional, Silingardi, Roberto, additional, Antonello, Michele, additional, Forcella, Edoardo, additional, Grego, Franco, additional, Spinella, Giovanni, additional, Di Gregorio, Sara, additional, Donati, Tommaso, additional, Sica, Simona, additional, Tinelli, Giovanni, additional, Ferri, Michelangelo, additional, Quaglino, Simone, additional, Vento, Vincenzo, additional, Carbonari, Luciano, additional, Lenti, Massimo, additional, Isernia, Giacomo, additional, Parlani, Giambattista, additional, Scrivere, Paola, additional, Furlan, Federico, additional, Mezzetto, Luca, additional, Mastrorilli, Davide, additional, Gennai, Stefano, additional, Leone, Nicola, additional, Iacono, Gustavo, additional, Turricchia, Giorgio Ubaldo, additional, Angiletta, Domenico, additional, Maione, Massimo, additional, Apostolou, Dimitri, additional, Pulli, Raffaele, additional, Fargion, Aaron, additional, Pratesi, Carlo, additional, Filippi, Federico, additional, De Angelis, Filippo, additional, Arici, Vittorio, additional, Bozzani, Antonio, additional, Luigi Molinari, Alessandro Carlo, additional, Rossi, Giovanni, additional, Brancadoro, Emidio Costantini, additional, Ferraris, Matteo, additional, Dorrucci, Vittorio, additional, Derone, Graziana, additional, Tolva, Valerio Stefano, additional, Segramora, Vittorio Maria, additional, Deleo, Gaetano, additional, Bracale, Umberto, additional, Guzzardi, Giuseppe, additional, Ferrer, Ciro, additional, Giudice, Rocco, additional, Sbarigia, Enrico, additional, Cuozzo, Simone, additional, Gattuso, Roberto, additional, Mansour, Wassim, additional, Di Marzo, Luca, additional, Grimaldi, Sabrina, additional, Corona, Mario, additional, Chisci, Emiliano, additional, Mechelagnoli, Stefano, additional, De Donato, Gianmarco, additional, Palasciano, Giancarlo, additional, Pasqui, Edoardo, additional, Candeloro, Laura, additional, Ricci, Carmelo, additional, Neri, Eugenio, additional, Mangialardi, Nicola, additional, Orrico, Matteo, additional, Fazzini, Stefano, additional, Ippoliti, Arnaldo, additional, Discalzi, Andrea, additional, Rossato, Denis, additional, Vio, Elias, additional, Galeazzi, Edoardo, additional, and Farneti, Fabrizio, additional

Published
2023
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50. Midterm results on a new self-expandable covered stent combined with branched stent grafts: Insights from a multicenter Italian registry

Author

Bertoglio, Luca, primary, Grandi, Alessandro, additional, Veraldi, Gian Franco, additional, Pulli, Raffaele, additional, Antonello, Michele, additional, Bonvini, Stefano, additional, Isernia, Giacomo, additional, Bellosta, Raffaello, additional, Buia, Francesco, additional, Silingardi, Roberto, additional, Domenico, Angiletta, additional, Roberto, Chiesa, additional, Luca, Di Marzo, additional, Loris, Flora, additional, Stefano, Gennai, additional, Rocco, Giudice, additional, Massimo, Lenti, additional, Nicola, Leone, additional, Sandro, Lepidi, additional, Andrea, Melloni, additional, Luca, Mezzetto, additional, Stefano, Michelagnoli, additional, Bruno, Migliara, additional, Domenico, Milite, additional, Davide, Pacini, additional, Enzo, Palazzo, additional, Alberto, Pecchio, additional, Matteo Alberto, Pegorer, additional, Paolo, Perini, additional, Michele, Piazza, additional, Giovanni, Pratesi, additional, Sonia, Ronchey, additional, Nicola, Spadoni, additional, Nicola, Tusini, additional, and Fabio, Verzini, additional

Published
2023
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