Search

Your search keyword '"Sikorski, Marcin"' showing total 472 results
Start Over Author "Sikorski, Marcin"

Refine your results

more »

more »

more »

more »
472 results on '"Sikorski, Marcin"'

1. Resolving non-equilibrium shape variations amongst millions of gold nanoparticles

Author

Shen, Zhou, Awel, Salah, Barty, Anton, Bean, Richard, Bielecki, Johan, Bergemann, Martin, Daurer, Benedikt J., Ekeberg, Tomas, Estillore, Armando D., Fangohr, Hans, Giewekemeyer, Klaus, Hunter, Mark S., Karnevskiy, Mikhail, Kirian, Richard A., Kirkwood, Henry, Kim, Yoonhee, Koliyadu, Jayanath, Lange, Holger, Letrun, Romain, Lübke, Jannik, Mall, Abhishek, Michelat, Thomas, Morgan, Andrew J., Roth, Nils, Samanta, Amit K., Sato, Tokushi, Sikorski, Marcin, Schulz, Florian, Vagovic, Patrik, Wollweber, Tamme, Worbs, Lena, Xavier, Paul Lourdu, Maia, Filipe R. N. C., Horke, Daniel A., Küpper, Jochen, Mancuso, Adrian P., Chapman, Henry N., Ayyer, Kartik, and Loh, N. Duane

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics
Abstract

Nanoparticles, exhibiting functionally relevant structural heterogeneity, are at the forefront of cutting-edge research. Now, high-throughput single-particle imaging (SPI) with x-ray free-electron lasers (XFELs) creates unprecedented opportunities for recovering the shape distributions of millions of particles that exhibit functionally relevant structural heterogeneity. To realize this potential, three challenges have to be overcome: (1) simultaneous parametrization of structural variability in real and reciprocal spaces; (2) efficiently inferring the latent parameters of each SPI measurement; (3) scaling up comparisons between $10^5$ structural models and $10^6$ XFEL-SPI measurements. Here, we describe how we overcame these three challenges to resolve the non-equilibrium shape distributions within millions of gold nanoparticles imaged at the European XFEL. These shape distributions allowed us to quantify the degree of asymmetry in these particles, discover a relatively stable `shape envelope' amongst nanoparticles, discern finite-size effects related to shape-controlling surfactants, and extrapolate nanoparticles' shapes to their idealized thermodynamic limit. Ultimately, these demonstrations show that XFEL SPI can help transform nanoparticle shape characterization from anecdotally interesting to statistically meaningful.

Published
2024

2. Ultrasound cavitation and exfoliation dynamics of 2D materials re-vealed in operando by X-ray free electron laser megahertz imaging

Author

Xiang, Kang, Huang, Shi, Song, Hongyuan, Bazhenov, Vasilii, Bellucci, Valerio, Birnsteinova, Sarlota, de Wijn, Raphael, Koliyadu, Jayanath C. P., Koua, Faisal H. M., Round, Adam, Round, Ekaterina, Sarma, Abhisakh, Sato, Tokushi, Sikorski, Marcin, Zhang, Yuhe, Asimakopoulou, Eleni Myrto, Villanueva-Perez, Pablo, Porfyrakis, Kyriakos, Tzanakis, Iakovos, Eskin, Dmitry G., Grobert, Nicole, Mancuso, Adrian, Bean, Richard, Vagovic, Patrik, and Mi, Jiawei

Subjects
Condensed Matter - Materials Science, Condensed Matter - Mesoscale and Nanoscale Physics, Physics - Fluid Dynamics
Abstract

Ultrasonic liquid phase exfoliation is a promising method for the production of two-dimensional (2D) layered materials. A large number of studies have been made in investigating the underlying ultrasound exfoliation mechanisms. However, due to the experimental challenges for capturing the highly transient and dynamic phenomena in real-time at sub-microsecond time and micrometer length scales simultaneously, most theories reported to date still remain elusive. Here, using the ultra-short X-ray Free Electron Laser pulses (~25ps) with a unique pulse train structure, we applied MHz X-ray Microscopy and machine-learning technique to reveal unambiguously the full cycles of the ultrasound cavitation and graphite layer exfoliation dynamics with sub-microsecond and micrometer resolution. Cyclic fatigue shock wave impacts produced by ultrasound cloud implosion were identified as the dominant mechanism to deflect and exfoliate graphite layers mechanically. For the graphite flakes, exfoliation rate as high as ~5 angstroms per shock wave impact was observed. For the HOPG graphite, the highest exfoliation rate was ~0.15 angstroms per impact. These new findings are scientifically and technologically important for developing industrial upscaling strategies for ultrasonic exfoliation of 2D materials.

Published
2023

3. SARS-CoV-2 Mpro responds to oxidation by forming disulfide and NOS/SONOS bonds

Author

Reinke, Patrick Y. A., Schubert, Robin, Oberthür, Dominik, Galchenkova, Marina, Rahmani Mashhour, Aida, Günther, Sebastian, Chretien, Anaïs, Round, Adam, Seychell, Brandon Charles, Norton-Baker, Brenna, Kim, Chan, Schmidt, Christina, Koua, Faisal H. M., Tolstikova, Alexandra, Ewert, Wiebke, Peña Murillo, Gisel Esperanza, Mills, Grant, Kirkwood, Henry, Brognaro, Hévila, Han, Huijong, Koliyadu, Jayanath, Schulz, Joachim, Bielecki, Johan, Lieske, Julia, Maracke, Julia, Knoska, Juraj, Lorenzen, Kristina, Brings, Lea, Sikorski, Marcin, Kloos, Marco, Vakili, Mohammad, Vagovic, Patrik, Middendorf, Philipp, de Wijn, Raphael, Bean, Richard, Letrun, Romain, Han, Seonghyun, Falke, Sven, Geng, Tian, Sato, Tokushi, Srinivasan, Vasundara, Kim, Yoonhee, Yefanov, Oleksandr M., Gelisio, Luca, Beck, Tobias, Doré, Andrew S., Mancuso, Adrian P., Betzel, Christian, Bajt, Saša, Redecke, Lars, Chapman, Henry N., Meents, Alke, Turk, Dušan, Hinrichs, Winfried, and Lane, Thomas J.

Published
2024
Full Text
View/download PDF

5. Unsupervised learning approaches to characterize heterogeneous samples using X-ray single particle imaging

Author

Zhuang, Yulong, Awel, Salah, Barty, Anton, Bean, Richard, Bielecki, Johan, Bergemann, Martin, Daurer, Benedikt J., Ekeberg, Tomas, Estillore, Armando D., Fangohr, Hans, Giewekemeyer, Klaus, Hunter, Mark S., Karnevskiy, Mikhail, Kirian, Richard A., Kirkwood, Henry, Kim, Yoonhee, Koliyadu, Jayanath, Lange, Holger, Letrun, Romain, Lübke, Jannik, Mall, Abhishek, Michelat, Thomas, Morgan, Andrew J., Roth, Nils, Samanta, Amit K., Sato, Tokushi, Shen, Zhou, Sikorski, Marcin, Schulz, Florian, Spence, John C. H., Vagovic, Patrik, Wollweber, Tamme, Worbs, Lena, Xavier, P. Lourdu, Yefanov, Oleksandr, Maia, Filipe R. N. C., Horke, Daniel A., Küpper, Jochen, Loh, N. Duane, Mancuso, Adrian P., Chapman, Henry N., and Ayyer, Kartik

Subjects
Electrical Engineering and Systems Science - Image and Video Processing, Condensed Matter - Mesoscale and Nanoscale Physics, Physics - Data Analysis, Statistics and Probability
Abstract

One of the outstanding analytical problems in X-ray single particle imaging (SPI) is the classification of structural heterogeneity, which is especially difficult given the low signal-to-noise ratios of individual patterns and that even identical objects can yield patterns that vary greatly when orientation is taken into consideration. We propose two methods which explicitly account for this orientation-induced variation and can robustly determine the structural landscape of a sample ensemble. The first, termed common-line principal component analysis (PCA) provides a rough classification which is essentially parameter-free and can be run automatically on any SPI dataset. The second method, utilizing variation auto-encoders (VAEs) can generate 3D structures of the objects at any point in the structural landscape. We implement both these methods in combination with the noise-tolerant expand-maximize-compress (EMC) algorithm and demonstrate its utility by applying it to an experimental dataset from gold nanoparticles with only a few thousand photons per pattern and recover both discrete structural classes as well as continuous deformations. These developments diverge from previous approaches of extracting reproducible subsets of patterns from a dataset and open up the possibility to move beyond studying homogeneous sample sets and study open questions on topics such as nanocrystal growth and dynamics as well as phase transitions which have not been externally triggered., Comment: 29 pages, 9 figures

Published
2021

6. Form factor determination of biological molecules with X-ray free electron laser small-angle scattering (XFEL-SAS)

Author

Blanchet, Clement E., Round, Adam, Mertens, Haydyn D. T., Ayyer, Kartik, Graewert, Melissa, Awel, Salah, Franke, Daniel, Dörner, Katerina, Bajt, Saša, Bean, Richard, Custódio, Tânia F., de Wijn, Raphael, Juncheng, E., Henkel, Alessandra, Gruzinov, Andrey, Jeffries, Cy M., Kim, Yoonhee, Kirkwood, Henry, Kloos, Marco, Knoška, Juraj, Koliyadu, Jayanath, Letrun, Romain, Löw, Christian, Makroczyova, Jana, Mall, Abhishek, Meijers, Rob, Pena Murillo, Gisel Esperanza, Oberthür, Dominik, Round, Ekaterina, Seuring, Carolin, Sikorski, Marcin, Vagovic, Patrik, Valerio, Joana, Wollweber, Tamme, Zhuang, Yulong, Schulz, Joachim, Haas, Heinrich, Chapman, Henry N., Mancuso, Adrian P., and Svergun, Dmitri

Published
2023
Full Text
View/download PDF

7. Megahertz pulse trains enable multi-hit serial femtosecond crystallography experiments at X-ray free electron lasers

Author

Holmes, Susannah, Kirkwood, Henry J, Bean, Richard, Giewekemeyer, Klaus, Martin, Andrew V, Hadian-Jazi, Marjan, Wiedorn, Max O, Oberthür, Dominik, Marman, Hugh, Adriano, Luigi, Al-Qudami, Nasser, Bajt, Saša, Barák, Imrich, Bari, Sadia, Bielecki, Johan, Brockhauser, Sandor, Coleman, Mathew A, Cruz-Mazo, Francisco, Danilevski, Cyril, Dörner, Katerina, Gañán-Calvo, Alfonso M, Graceffa, Rita, Fanghor, Hans, Heymann, Michael, Frank, Matthias, Kaukher, Alexander, Kim, Yoonhee, Kobe, Bostjan, Knoška, Juraj, Laurus, Torsten, Letrun, Romain, Maia, Luis, Messerschmidt, Marc, Metz, Markus, Michelat, Thomas, Mills, Grant, Molodtsov, Serguei, Monteiro, Diana CF, Morgan, Andrew J, Münnich, Astrid, Peña Murillo, Gisel E, Previtali, Gianpietro, Round, Adam, Sato, Tokushi, Schubert, Robin, Schulz, Joachim, Shelby, Megan, Seuring, Carolin, Sellberg, Jonas A, Sikorski, Marcin, Silenzi, Alessandro, Stern, Stephan, Sztuk-Dambietz, Jola, Szuba, Janusz, Trebbin, Martin, Vagovic, Patrick, Ve, Thomas, Weinhausen, Britta, Wrona, Krzysztof, Xavier, Paul Lourdu, Xu, Chen, Yefanov, Oleksandr, Nugent, Keith A, Chapman, Henry N, Mancuso, Adrian P, Barty, Anton, Abbey, Brian, and Darmanin, Connie

Subjects
Inorganic Chemistry, Chemical Sciences, Physical Sciences, Biological Sciences, Crystallography, X-Ray, Electrons, Lasers, Radiography, X-Rays
Abstract

The European X-ray Free Electron Laser (XFEL) and Linac Coherent Light Source (LCLS) II are extremely intense sources of X-rays capable of generating Serial Femtosecond Crystallography (SFX) data at megahertz (MHz) repetition rates. Previous work has shown that it is possible to use consecutive X-ray pulses to collect diffraction patterns from individual crystals. Here, we exploit the MHz pulse structure of the European XFEL to obtain two complete datasets from the same lysozyme crystal, first hit and the second hit, before it exits the beam. The two datasets, separated by

Published
2022

8. Integration and first operation of the Gotthard-II detector at European XFEL

Author

Ramilli, Marco, Ahmed, Karim, de Wijn, Raphael, Dietze, Thomas, Fernandes, Bruno, Hammer, David, Jiang, Yifeng, Khakhulin, Dmitry, Koliyadu, Jayanath C.P., Letrun, Romain, Liu, Jia, Lopez-Cuenca, Carlos, Mezza, Davide, Milne, Christopher, Mozzanica, Aldo, Parenti, Andrea, Sato, Tokushi, Schmidt, Philipp, Schmitt, Bernd, Sikorski, Marcin, Turcato, Monica, Uemura, Yohei, Wang, Hao, Yousef, Hazem, and Zhang, Jiaguo

Published
2024
Full Text
View/download PDF

9. 3D diffractive imaging of nanoparticle ensembles using an X-ray laser

Author

Ayyer, Kartik, Xavier, P. Lourdu, Bielecki, Johan, Shen, Zhou, Daurer, Benedikt J., Samanta, Amit K., Awel, Salah, Bean, Richard, Barty, Anton, Ekeberg, Tomas, Estillore, Armando D., Giewekemeyer, Klaus, Hunter, Mark S., Kirian, Richard A., Kirkwood, Henry, Kim, Yoonhee, Koliyadu, Jayanath, Lange, Holger, Letruin, Romain, Lübke, Jannik, Morgan, Andrew J., Roth, Nils, Sato, Tokushi, Sikorski, Marcin, Schulz, Florian, Spence, John C. H., Vagovic, Patrik, Wollweber, Tamme, Worbs, Lena, Yefanov, Oleksandr, Zhuang, Yulong, Maia, Filipe R. N. C., Horke, Daniel A., Küpper, Jochen, Loh, N. Duane, Mancuso, Adrian P., and Chapman, Henry N.

Subjects
Physics - Applied Physics, Electrical Engineering and Systems Science - Image and Video Processing, Physics - Optics
Abstract

We report the 3D structure determination of gold nanoparticles (AuNPs) by X-ray single particle imaging (SPI). Around 10 million diffraction patterns from gold nanoparticles were measured in less than 100 hours of beam time, more than 100 times the amount of data in any single prior SPI experiment, using the new capabilities of the European X-ray free electron laser which allow measurements of 1500 frames per second. A classification and structural sorting method was developed to disentangle the heterogeneity of the particles and to obtain a resolution of better than 3 nm. With these new experimental and analytical developments, we have entered a new era for the SPI method and the path towards close-to-atomic resolution imaging of biomolecules is apparent., Comment: 25 pages, 5 main figures, 6 supplementary figures, 2 supplementary movies (link in document)

Published
2020

10. Megahertz single-particle imaging at the European XFEL

Author

Sobolev, Egor, Zolotarev, Serguey, Giewekemeyer, Klaus, Bielecki, Johan, Okamoto, Kenta, Reddy, Hemanth K. N., Andreasson, Jakob, Ayyer, Kartik, Barak, Imrich, Bari, Sadia, Barty, Anton, Bean, Richard, Bobkov, Sergey, Chapman, Henry N., Chojnowski, Grzegorz, Daurer, Benedikt J., Dörner, Katerina, Ekeberg, Tomas, Flückiger, Leonie, Galzitskaya, Oxana, Gelisio, Luca, Hauf, Steffen, Hogue, Brenda G., Horke, Daniel A., Hosseinizadeh, Ahmad, Ilyin, Vyacheslav, Jung, Chulho, Kim, Chan, Kim, Yoonhee, Kirian, Richard A., Kirkwood, Henry, Kulyk, Olena, Letrun, Romain, Loh, Duane, Messerschmidt, Marc, Mühlig, Kerstin, Ourmazd, Abbas, Raab, Natascha, Rode, Andrei V., Rose, Max, Round, Adam, Sato, Takushi, Schubert, Robin, Schwander, Peter, Sellberg, Jonas A., Sikorski, Marcin, Silenzi, Alessandro, Song, Changyong, Spence, John C. H., Stern, Stephan, Sztuk-Dambietz, Jolanta, Teslyuk, Anthon, Timneanu, Nicusor, Trebbin, Martin, Uetrecht, Charlotte, Weinhausen, Britta, Williams, Garth J., Xavier, P Lourdu, Xu, Chen, Vartanyants, Ivan, Lamzin, Victor, Mancuso, Adrian, and Maia, Filipe R. N. C.

Subjects
Physics - Instrumentation and Detectors, Physics - Biological Physics
Abstract

The emergence of high repetition-rate X-ray free-electron lasers (XFELs) powered by superconducting accelerator technology enables the measurement of significantly more experimental data per day than was previously possible. The European XFEL will soon provide 27,000 pulses per second, more than two orders of magnitude more than any other XFEL. The increased pulse rate is a key enabling factor for single-particle X-ray diffractive imaging, which relies on averaging the weak diffraction signal from single biological particles. Taking full advantage of this new capability requires that all experimental steps, from sample preparation and delivery to the acquisition of diffraction patterns, are compatible with the increased pulse repetition rate. Here, we show that single-particle imaging can be performed using X-ray pulses at megahertz repetition rates. The obtained results pave the way towards exploiting high repetition-rate X-ray free-electron lasers for single-particle imaging at their full repetition rate.

Published
2019
Full Text
View/download PDF

11. Femtosecond laser produced periodic plasma in a colloidal crystal probed by XFEL radiation

Author

Mukharamova, Nastasia, Lazarev, Sergey, Meijer, Janne-Mieke, Gorobtsov, Oleg Yu., Singer, Andrej, Chollet, Matthieu, Bussmann, Michael, Dzhigaev, Dmitry, Feng, Yiping, Garten, Marco, Huebl, Axel, Kluge, Thomas, Kurta, Ruslan P., Lipp, Vladimir, Santra, Robin, Sikorski, Marcin, Song, Sanghoon, Williams, Garth, Zhu, Diling, Ziaja-Motyka, Beata, Cowan, Thomas, Petukhov, Andrei V., and Vartanyants, Ivan A.

Subjects
Condensed Matter - Soft Condensed Matter, Physics - Plasma Physics
Abstract

With the rapid development of short-pulse intense laser sources, studies of matter under extreme irradiation conditions enter further unexplored regimes. In addition, an application of X-ray Free- Electron Lasers (XFELs), delivering intense femtosecond X-ray pulses allows to investigate sample evolution in IR pump - X-ray probe experiments with an unprecedented time resolution. Here we present the detailed study of periodic plasma created from the colloidal crystal. Both experimental data and theory modeling show that the periodicity in the sample survives to a large extent the extreme excitation and shock wave propagation inside the colloidal crystal. This feature enables probing the excited crystal, using the powerful Bragg peak analysis, in contrast to the conventional studies of dense plasma created from bulk samples for which probing with Bragg diffraction technique is not possible. X-ray diffraction measurements of excited colloidal crystals may then lead towards a better understanding of matter phase transitions under extreme irradiation conditions., Comment: 52 pages, 22 figures, 64 references

Published
2019
Full Text
View/download PDF

12. Origin of vibrational wavepacket dynamics in Fe carbene photosensitizer determined with femtosecond X-ray emission and scattering

Author

Kunnus, Kristjan, Vacher, Morgane, Harlang, Tobias C. B., Kjær, Kasper S., Haldrup, Kristoffer, Biasin, Elisa, van Driel, Tim B., Pápa, Mátyás, Chabera, Pavel, Liu, Yizhu, Tatsuno, Hideyuki, Timm, Cornelia, Källman, Erik, Delcey, Mickaël, Hartsock, Robert W., Reinhard, Marco E., Koroidov, Sergey, Laursen, Mads G., Hansen, Frederik B., Vester, Peter, Christensen, Morten, Sandberg, Lise, Németh, Zoltán, Szemes, Dorottya Sárosiné, Bajnóczi, Éva, Alonso-Mori, Roberto, Glownia, James M., Nelson, Silke, Sikorski, Marcin, Sokaras, Dimosthenis, Lemke, Henrik T., Canton, Sophie, Møller, Klaus B., Nielsen, Martin M., Vankó, György, Wärnmark, Kenneth, Sundström, Villy, Persson, Petter, Lundberg, Marcus, Uhlig, Jens, and Gaffney, Kelly J.

Subjects
Physics - Chemical Physics
Abstract

Disentangling the dynamics of electrons and nuclei during nonadiabatic molecular transformations remains a considerable experimental challenge. Here we have investigated photoinduced electron transfer dynamics following a metal-to-ligand charge-transfer (MLCT) excitation of the [Fe(bmip)2]2+ photosensitizer, where bmip = 2,6-bis(3-methyl-imidazole-1- ylidine)-pyridine, with simultaneous femtosecond-resolution Fe K{\alpha} and K\b{eta} X-ray Emission Spectroscopy (XES) and Wide Angle X-ray Scattering (WAXS). This measurement clearly shows temporal oscillations in the XES and WAXS difference signals with the same 278 fs period oscillation. The oscillatory signal originates from an Fe-ligand stretching mode vibrational wavepacket on a triplet metal-centered (3MC) excited state surface. The vibrational wavepacket is created by 40% of the excited population that undergoes electron transfer from the non-equilibrium MLCT excited state to the 3MC excited state with a 110 fs time constant, while the other 60% relaxes to a 3MLCT excited state in parallel. The sensitivity of the K{\alpha} XES spectrum to molecular structure results from core-level vibronic coupling, due to a 0.7% average Fe-ligand bond length difference in the lowest energy geometry of the 1s and 2p core-ionized states. These results highlight the importance of vibronic effects in time-resolved XES experiments and demonstrate the role of metal-centered excited states in the electronic excited state relaxation dynamics of an Fe carbene photosensitizer.

Published
2019
Full Text
View/download PDF

13. Exploring the usability and user experience of social media apps through a text mining approach

Author

Baj-Rogowska Anna and Sikorski Marcin

Subjects
usability, user experience, 5es model, honeycomb model, text mining, mobile apps, Production management. Operations management, TS155-194
Abstract

This study aims to evaluate the applicability of a text mining approach for extracting UUX-related issues from a dataset of user comments and not to evaluate the Instagram (IG) app. This study analyses textual data mined from reviews in English written by IG mobile application users. The article’s authors used text mining (based on the LDA algorithm) to identify the main UUX-related topics. Next, they mapped the identified topics with known theoretical constructs to place them in their nomological network relevant to the usability (the 5Es framework by Quesenbery) and UX (the Honeycomb model by Morville). Finally, to expand the study with an emotional diagnosis, sentiment analysis was performed on two levels: (i) for each recognised topic, and (ii) for the full dataset to uncover general insights into users’ emotions within all reviews. The case study of the IG app confirms the usefulness of user feedback data for software development and points out that the review data have the potential for the early detection of frustration and negative feelings introduced during the use of the application. Conducting conventional UUX evaluations with users is problematic since they are remotely located, and the user-generated content of a social app undergoes continuous and frequent changes. Thus, the consecutive stages of the proposed methodology, based on text mining algorithms, constitute a proposed framework for examining the user-perceived quality projection of applications from user feedback, and they are the main contribution of this article. The used approach can be valuable for helping developers, designers and researchers to reveal user problems and fulfil user satisfaction regarding UUX aspects for specific software features.

Published
2023
Full Text
View/download PDF

14. Megahertz single-particle imaging at the European XFEL

Author

Sobolev, Egor, Zolotarev, Sergei, Giewekemeyer, Klaus, Bielecki, Johan, Okamoto, Kenta, Reddy, Hemanth KN, Andreasson, Jakob, Ayyer, Kartik, Barak, Imrich, Bari, Sadia, Barty, Anton, Bean, Richard, Bobkov, Sergey, Chapman, Henry N, Chojnowski, Grzegorz, Daurer, Benedikt J, Dörner, Katerina, Ekeberg, Tomas, Flückiger, Leonie, Galzitskaya, Oxana, Gelisio, Luca, Hauf, Steffen, Hogue, Brenda G, Horke, Daniel A, Hosseinizadeh, Ahmad, Ilyin, Vyacheslav, Jung, Chulho, Kim, Chan, Kim, Yoonhee, Kirian, Richard A, Kirkwood, Henry, Kulyk, Olena, Küpper, Jochen, Letrun, Romain, Loh, N Duane, Lorenzen, Kristina, Messerschmidt, Marc, Mühlig, Kerstin, Ourmazd, Abbas, Raab, Natascha, Rode, Andrei V, Rose, Max, Round, Adam, Sato, Takushi, Schubert, Robin, Schwander, Peter, Sellberg, Jonas A, Sikorski, Marcin, Silenzi, Alessandro, Song, Changyong, Spence, John CH, Stern, Stephan, Sztuk-Dambietz, Jolanta, Teslyuk, Anthon, Timneanu, Nicusor, Trebbin, Martin, Uetrecht, Charlotte, Weinhausen, Britta, Williams, Garth J, Xavier, P Lourdu, Xu, Chen, Vartanyants, Ivan A, Lamzin, Victor S, Mancuso, Adrian, and Maia, Filipe RNC

Abstract

The emergence of high repetition-rate X-ray free-electron lasers (XFELs) powered by superconducting accelerator technology enables the measurement of significantly more experimental data per day than was previously possible. The European XFEL is expected to provide 27,000 pulses per second, over two orders of magnitude more than any other XFEL. The increased pulse rate is a key enabling factor for single-particle X-ray diffractive imaging, which relies on averaging the weak diffraction signal from single biological particles. Taking full advantage of this new capability requires that all experimental steps, from sample preparation and delivery to the acquisition of diffraction patterns, are compatible with the increased pulse repetition rate. Here, we show that single-particle imaging can be performed using X-ray pulses at megahertz repetition rates. The results obtained pave the way towards exploiting high repetition-rate X-ray free-electron lasers for single-particle imaging at their full repetition rate.

Published
2020

15. Femtosecond laser produced periodic plasma in a colloidal crystal probed by XFEL radiation.

Author

Mukharamova, Nastasia, Lazarev, Sergey, Meijer, Janne-Mieke, Gorobtsov, Oleg Yu, Singer, Andrej, Chollet, Matthieu, Bussmann, Michael, Dzhigaev, Dmitry, Feng, Yiping, Garten, Marco, Huebl, Axel, Kluge, Thomas, Kurta, Ruslan P, Lipp, Vladimir, Santra, Robin, Sikorski, Marcin, Song, Sanghoon, Williams, Garth, Zhu, Diling, Ziaja-Motyka, Beata, Cowan, Thomas E, Petukhov, Andrei V, and Vartanyants, Ivan A

Subjects
cond-mat.soft, physics.plasm-ph
Abstract

With the rapid development of short-pulse intense laser sources, studies of matter under extreme irradiation conditions enter further unexplored regimes. In addition, an application of X-ray Free-Electron Lasers (XFELs) delivering intense femtosecond X-ray pulses, allows to investigate sample evolution in IR pump - X-ray probe experiments with an unprecedented time resolution. Here we present a detailed study of the periodic plasma created from the colloidal crystal. Both experimental data and theory modeling show that the periodicity in the sample survives to a large extent the extreme excitation and shock wave propagation inside the colloidal crystal. This feature enables probing the excited crystal, using the powerful Bragg peak analysis, in contrast to the conventional studies of dense plasma created from bulk samples for which probing with Bragg diffraction technique is not possible. X-ray diffraction measurements of excited colloidal crystals may then lead towards a better understanding of matter phase transitions under extreme irradiation conditions.

Published
2020

16. Resolving Nonequilibrium Shape Variations among Millions of Gold Nanoparticles

Author

Shen, Zhou, primary, Xavier, Paul Lourdu, additional, Bean, Richard, additional, Bielecki, Johan, additional, Bergemann, Martin, additional, Daurer, Benedikt J., additional, Ekeberg, Tomas, additional, Estillore, Armando D., additional, Fangohr, Hans, additional, Giewekemeyer, Klaus, additional, Karnevskiy, Mikhail, additional, Kirian, Richard A., additional, Kirkwood, Henry, additional, Kim, Yoonhee, additional, Koliyadu, Jayanath C. P., additional, Lange, Holger, additional, Letrun, Romain, additional, Lübke, Jannik, additional, Mall, Abhishek, additional, Michelat, Thomas, additional, Morgan, Andrew J., additional, Roth, Nils, additional, Samanta, Amit K., additional, Sato, Tokushi, additional, Sikorski, Marcin, additional, Schulz, Florian, additional, Vagovic, Patrik, additional, Wollweber, Tamme, additional, Worbs, Lena, additional, Maia, Filipe, additional, Horke, Daniel Alfred, additional, Küpper, Jochen, additional, Mancuso, Adrian P., additional, Chapman, Henry, additional, Ayyer, Kartik, additional, and Loh, N. Duane, additional

Published
2024
Full Text
View/download PDF

17. Crystal structure of a bacterial photoactivated adenylate cyclase determined at room temperature by serial femtosecond crystallography

Author

Kapetanaki, Sofia M, primary, Coquelle, Nicolas, additional, von Stetten, David, additional, Byrdin, Martin, additional, Rios-Santacruz, Ronald, additional, Bean, Richard, additional, Bielecki, Johan, additional, Boudjelida, Mohamed, additional, Fekete, Zsuzsana, additional, Grime, Geoffrey W, additional, Han, Huijong, additional, Hatton, Caitlin, additional, Kantamneni, Sravya, additional, Kharitonov, Konstantin, additional, Kim, Chan, additional, Kloos, Marco, additional, Koua, Faisal H.M., additional, de Diego Martinez, Inaki, additional, Melo, Diogo, additional, Rane, Lukas, additional, Round, Adam, additional, Round, Ekaterina, additional, Sarma, Abhisakh, additional, Schubert, Robin, additional, Schulz, Joachim, additional, Sikorski, Marcin, additional, Vakili, Mohammad, additional, Valerio, Joana, additional, Vitas, Jovana, additional, de Wijn, Raphael, additional, Wrona, Agnieszka, additional, Zala, Ninon, additional, Pearson, Arwen, additional, Dorner, Katerina, additional, Schiro, Giorgio, additional, Garman, Elspeth F, additional, Lukacs, Andras, additional, and Weik, Martin, additional

Published
2024
Full Text
View/download PDF

18. A multi-million image Serial Femtosecond Crystallography dataset collected at the European XFEL

Author

Kirkwood, Henry J., de Wijn, Raphael, Mills, Grant, Letrun, Romain, Kloos, Marco, Vakili, Mohammad, Karnevskiy, Mikhail, Ahmed, Karim, Bean, Richard J., Bielecki, Johan, Dall’Antonia, Fabio, Kim, Yoonhee, Kim, Chan, Koliyadu, Jayanath, Round, Adam, Sato, Tokushi, Sikorski, Marcin, Vagovič, Patrik, Sztuk-Dambietz, Jolanta, and Mancuso, Adrian P.

Published
2022
Full Text
View/download PDF

19. Data reduction activities at European XFEL: early results

Author

Sobolev, Egor, primary, Schmidt, Philipp, additional, Malka, Janusz, additional, Hammer, David, additional, Boukhelef, Djelloul, additional, Möller, Johannes, additional, Ahmed, Karim, additional, Bean, Richard, additional, Bermúdez Macías, Ivette Jazmín, additional, Bielecki, Johan, additional, Bösenberg, Ulrike, additional, Carinan, Cammille, additional, Dall’Antonia, Fabio, additional, Esenov, Sergey, additional, Fangohr, Hans, additional, Ferreira de Lima, Danilo Enoque, additional, Ferreira Maia, Luís Gonçalo, additional, Firoozi, Hadi, additional, Flucke, Gero, additional, Gessler, Patrick, additional, Giovanetti, Gabriele, additional, Koliyadu, Jayanath, additional, Madsen, Anders, additional, Michelat, Thomas, additional, Schuh, Michael, additional, Sikorski, Marcin, additional, Silenzi, Alessandro, additional, Sztuk-Dambietz, Jolanta, additional, Turcato, Monica, additional, Turkot, Oleksii, additional, Wrigley, James, additional, Aplin, Steve, additional, Hauf, Steffen, additional, Wrona, Krzysztof, additional, and Gelisio, Luca, additional

Published
2024
Full Text
View/download PDF

20. Digital Innovations and Smart Solutions for Society and Economy: Pros and Cons

Author

Sikorski Marcin

Subjects
digital innovations, digital services, artificial intelligence, smart services, risk assessment, risk management, m10, Management. Industrial management, HD28-70, Business, HF5001-6182
Abstract

Recent developments in artificial intelligence (AI) may involve significant potential threats to personal data privacy, national security, and social and economic stability. AI-based solutions are often promoted as “intelligent” or “smart” because they are autonomous in optimizing various processes. Because they can modify their behavior without human supervision by analyzing data from the environment, AI-based systems may be more prone to malfunctions and malicious activities than conventional software systems. Moreover, due to existing regulatory gaps, development and operation of AI-based products are not yet subject to adequate risk management and administrative supervision. Resonating to recent reports about potential threats resulting from AI-based systems, this paper presents an outline of a prospective risk assessment for adaptive and autonomous products. This research resulted in extensive catalogs of possible damages, initiating events, and preventive policies that can be useful for risk managers involved in conducting risk assessment procedures for AI-based systems. The paper concludes with the analysis and discussion of changes in business, legal, and institutional environments required to ensure the public that AI-based solutions can be trusted, are transparent and safe, and can improve the quality of life.

Published
2021
Full Text
View/download PDF

21. Emergence of anomalous dynamics in soft matter probed at the European XFEL

Author

Lehmkühler, Felix, Dallari, Francesco, Jain, Avni, Sikorski, Marcin, Möller, Johannes, Frenzel, Lara, Lokteva, Irina, Mills, Grant, Walther, Michael, Sinn, Harald, Schulz, Florian, Dartsch, Michael, Markmann, Verena, Bean, Richard, Kim, Yoonhee, Vagovic, Patrik, Madsen, Anders, Mancuso, Adrian P., and Grübel, Gerhard

Published
2020

22. Structure of photosystem II and substrate binding at room temperature

Author

Young, Iris D, Ibrahim, Mohamed, Chatterjee, Ruchira, Gul, Sheraz, Fuller, Franklin D, Koroidov, Sergey, Brewster, Aaron S, Tran, Rosalie, Alonso-Mori, Roberto, Kroll, Thomas, Michels-Clark, Tara, Laksmono, Hartawan, Sierra, Raymond G, Stan, Claudiu A, Hussein, Rana, Zhang, Miao, Douthit, Lacey, Kubin, Markus, de Lichtenberg, Casper, Vo Pham, Long, Nilsson, Håkan, Cheah, Mun Hon, Shevela, Dmitriy, Saracini, Claudio, Bean, Mackenzie A, Seuffert, Ina, Sokaras, Dimosthenis, Weng, Tsu-Chien, Pastor, Ernest, Weninger, Clemens, Fransson, Thomas, Lassalle, Louise, Bräuer, Philipp, Aller, Pierre, Docker, Peter T, Andi, Babak, Orville, Allen M, Glownia, James M, Nelson, Silke, Sikorski, Marcin, Zhu, Diling, Hunter, Mark S, Lane, Thomas J, Aquila, Andy, Koglin, Jason E, Robinson, Joseph, Liang, Mengning, Boutet, Sébastien, Lyubimov, Artem Y, Uervirojnangkoorn, Monarin, Moriarty, Nigel W, Liebschner, Dorothee, Afonine, Pavel V, Waterman, David G, Evans, Gwyndaf, Wernet, Philippe, Dobbek, Holger, Weis, William I, Brunger, Axel T, Zwart, Petrus H, Adams, Paul D, Zouni, Athina, Messinger, Johannes, Bergmann, Uwe, Sauter, Nicholas K, Kern, Jan, Yachandra, Vittal K, and Yano, Junko

Subjects
Plant Biology, Biological Sciences, Physical Sciences, Ammonia, Bacterial Proteins, Binding Sites, Crystallization, Cyanobacteria, Electrons, Lasers, Manganese, Models, Molecular, Oxygen, Photosystem II Protein Complex, Substrate Specificity, Temperature, Water, General Science & Technology
Abstract

Light-induced oxidation of water by photosystem II (PS II) in plants, algae and cyanobacteria has generated most of the dioxygen in the atmosphere. PS II, a membrane-bound multi-subunit pigment protein complex, couples the one-electron photochemistry at the reaction centre with the four-electron redox chemistry of water oxidation at the Mn4CaO5 cluster in the oxygen-evolving complex (OEC). Under illumination, the OEC cycles through five intermediate S-states (S0 to S4), in which S1 is the dark-stable state and S3 is the last semi-stable state before O-O bond formation and O2 evolution. A detailed understanding of the O-O bond formation mechanism remains a challenge, and will require elucidation of both the structures of the OEC in the different S-states and the binding of the two substrate waters to the catalytic site. Here we report the use of femtosecond pulses from an X-ray free electron laser (XFEL) to obtain damage-free, room temperature structures of dark-adapted (S1), two-flash illuminated (2F; S3-enriched), and ammonia-bound two-flash illuminated (2F-NH3; S3-enriched) PS II. Although the recent 1.95 Å resolution structure of PS II at cryogenic temperature using an XFEL provided a damage-free view of the S1 state, measurements at room temperature are required to study the structural landscape of proteins under functional conditions, and also for in situ advancement of the S-states. To investigate the water-binding site(s), ammonia, a water analogue, has been used as a marker, as it binds to the Mn4CaO5 cluster in the S2 and S3 states. Since the ammonia-bound OEC is active, the ammonia-binding Mn site is not a substrate water site. This approach, together with a comparison of the native dark and 2F states, is used to discriminate between proposed O-O bond formation mechanisms.

Published
2016

23. First operation of the JUNGFRAU detector in 16-memory cell mode at European XFEL

Author

Sikorski, Marcin, primary, Ramilli, Marco, additional, de Wijn, Raphael, additional, Hinger, Viktoria, additional, Mozzanica, Aldo, additional, Schmitt, Bernd, additional, Han, Huijong, additional, Bean, Richard, additional, Bielecki, Johan, additional, Bortel, Gábor, additional, Dietze, Thomas, additional, Faigel, Gyula, additional, Kharitonov, Konstantin, additional, Kim, Chan, additional, Koliyadu, Jayanath C. P., additional, Koua, Faisal H. M., additional, Letrun, Romain, additional, Lopez, Luis M., additional, Reimers, Nadja, additional, Round, Adam, additional, Sarma, Abhisakh, additional, Sato, Tokushi, additional, Tegze, Miklós, additional, and Turcato, Monica, additional

Published
2023
Full Text
View/download PDF

24. Structure of the Lysinibacillus sphaericus Tpp49Aa1 pesticidal protein elucidated from natural crystals using MHz-SFX

Author

Williamson, Lainey J., primary, Galchenkova, Marina, additional, Best, Hannah L., additional, Bean, Richard J., additional, Munke, Anna, additional, Awel, Salah, additional, Pena, Gisel, additional, Knoska, Juraj, additional, Schubert, Robin, additional, Dörner, Katerina, additional, Park, Hyun-Woo, additional, Bideshi, Dennis K., additional, Henkel, Alessandra, additional, Kremling, Viviane, additional, Klopprogge, Bjarne, additional, Lloyd-Evans, Emyr, additional, Young, Mark T., additional, Valerio, Joana, additional, Kloos, Marco, additional, Sikorski, Marcin, additional, Mills, Grant, additional, Bielecki, Johan, additional, Kirkwood, Henry, additional, Kim, Chan, additional, de Wijn, Raphael, additional, Lorenzen, Kristina, additional, Xavier, Paul Lourdu, additional, Rahmani Mashhour, Aida, additional, Gelisio, Luca, additional, Yefanov, Oleksandr, additional, Mancuso, Adrian P., additional, Federici, Brian A., additional, Chapman, Henry N., additional, Crickmore, Neil, additional, Rizkallah, Pierre J., additional, Berry, Colin, additional, and Oberthür, Dominik, additional

Published
2023
Full Text
View/download PDF

25. Integration and first operation of the Gotthard-II detector at European XFEL

Author

Ramilli, Marco, primary, Ahmed, Karim, additional, de Wijin, Raphael, additional, Dietze, Thomas, additional, Fernandes, Bruno, additional, Hammer, David, additional, Jiang, Yifeng, additional, Khakhulin, Dmitry, additional, Koliyadu, Jayanath C.P., additional, Letrun, Romain, additional, Liu, Jia, additional, Lopez-Cuenca, Carlos, additional, Mezza, Davide, additional, Milne, Christopher, additional, Mozzanica, Aldo, additional, Parenti, Andrea, additional, Sato, Tokushi, additional, Schmidt, Philipp, additional, Schmitt, Bernd, additional, Sikorski, Marcin, additional, Turcato, Monica, additional, Uemura, Yohei, additional, Wang, Hao, additional, Yousef, Hazem, additional, and Zhang, Jiaguo, additional

Published
2023
Full Text
View/download PDF

26. Demonstration of feasibility of X-ray free electron laser studies of dynamics of nanoparticles in entangled polymer melts.

Author

Carnis, Jerome, Cha, Wonsuk, Wingert, James, Kang, Jinback, Jiang, Zhang, Song, Sanghoon, Sikorski, Marcin, Robert, Aymeric, Gutt, Christian, Chen, San-Wen, Dai, Yeling, Ma, Yicong, Guo, Hongyu, Lurio, Laurence B, Shpyrko, Oleg, Narayanan, Suresh, Cui, Mengmeng, Kosif, Irem, Emrick, Todd, Russell, Thomas P, Lee, Hae Cheol, Yu, Chung-Jong, Grübel, Gerhard, Sinha, Sunil K, and Kim, Hyunjung

Abstract

The recent advent of hard x-ray free electron lasers (XFELs) opens new areas of science due to their exceptional brightness, coherence, and time structure. In principle, such sources enable studies of dynamics of condensed matter systems over times ranging from femtoseconds to seconds. However, the studies of "slow" dynamics in polymeric materials still remain in question due to the characteristics of the XFEL beam and concerns about sample damage. Here we demonstrate the feasibility of measuring the relaxation dynamics of gold nanoparticles suspended in polymer melts using X-ray photon correlation spectroscopy (XPCS), while also monitoring eventual X-ray induced damage. In spite of inherently large pulse-to-pulse intensity and position variations of the XFEL beam, measurements can be realized at slow time scales. The X-ray induced damage and heating are less than initially expected for soft matter materials.

Published
2014

27. Operational experience with Adaptive Gain Integrating Pixel Detectors at European XFEL.

Author

Sztuk-Dambietz, Jolanta, Rovensky, Vratko, Klujev, Alexander, Laurus, Torsten, Trunk, Ulrich, Ahmed, Karim, Meyer, Olivier, Möller, Johannes, Parenti, Andrea, Raab, Natascha, Shayduk, Roman, Sikorski, Marcin, Ansaldi, Gabriele, Bösenberg, Ulrike, Luis, Lopez M., Muenich, Astrid, Preston, Thomas R., Schmidt, Philipp, Stern, Stephan, and Bean, Richard

Subjects
FREE electron lasers, PROGRAMMABLE controllers, ULTRASHORT laser pulses, DETECTORS, X-ray lasers, INFORMATION storage & retrieval systems
Abstract

The European X-ray Free Electron Laser (European XFEL) is a cutting-edge user facility that generates per second up to 27,000 ultra-short, spatially coherent X-ray pulses within an energy range of 0.26 to more than 20 keV. Specialized instrumentation, including various 2D X-ray detectors capable of handling the unique time structure of the beam, is required. The one-megapixel AGIPD (AGIPD1M) detectors, developed for the European XFEL by the AGIPD Consortium, are the primary detectors used for user experiments at the SPB/SFX and MID instruments. The first AGIPD1M detector was installed at SPB/SFX when the facility began operation in 2017, and the second one was installed at MID in November 2018. The AGIPD detector systems require a dedicated infrastructure, well-defined safety systems, and high-level control procedures to ensure stable and safe operation. As of now, the AGIPD1M detectors installed at the SPB/SFX and MID experimental end stations are fully integrated into the European XFEL environment, including mechanical integration, vacuum, power, control, data acquisition, and data processing systems. Specific high-level procedures allow facilitated detector control, and dedicated interlock systems based on Programmable Logic Controllers ensure detector safety in case of power, vacuum, or cooling failure. The first 6 years of operation have clearly demonstrated that the AGIPD1M detectors provide high-quality scientific results. The collected data, along with additional dedicated studies, have also enabled the identification and quantification of issues related to detector performance, ensuring stable operation. Characterization and calibration of detectors are among the most critical and challenging aspects of operation due to their complex nature. A methodology has been developed to enable detector characterization and data correction, both in near real-time (online) and offline mode. The calibration process optimizes detector performance and ensures the highest quality of experimental results. Overall, the experience gained from integrating and operating the AGIPD detectors at the European XFEL, along with the developed methodology for detector characterization and calibration, provides valuable insights for the development of next-generation detectors for Free Electron Laser X-ray sources. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

30. Femtosecond electronic structure response to high intensity XFEL pulses probed by iron X-ray emission spectroscopy

Author

Alonso-Mori, Roberto, Sokaras, Dimosthenis, Cammarata, Marco, Ding, Yuantao, Feng, Yiping, Fritz, David, Gaffney, Kelly J., Hastings, Jerome, Kao, Chi-Chang, Lemke, Henrik T., Maxwell, Timothy, Robert, Aymeric, Schropp, Andreas, Seiboth, Frank, Sikorski, Marcin, Song, Sanghoon, Weng, Tsu-Chien, Zhang, Wenkai, Glenzer, Siegfried, Bergmann, Uwe, and Zhu, Diling

Published
2020
Full Text
View/download PDF

31. Digital Interaction and Machine Intelligence

Author

Biele, Cezary, Kacprzyk, Janusz, Kopeć, Wiesław, Owsiński, Jan W., Romanowski, Andrzej, and Sikorski, Marcin

Subjects
Computational Intelligence, AI, MIDI 2022, MIDI, Machine Intelligence, Digital Interaction, bic Book Industry Communication::U Computing & information technology::UY Computer science::UYQ Artificial intelligence, bic Book Industry Communication::U Computing & information technology::UN Databases, bic Book Industry Communication::U Computing & information technology::UY Computer science::UYQ Artificial intelligence::UYQM Machine learning
Abstract

This open access book presents the proceedings of the 10th Machine Intelligence and Digital Interaction Conference. Artificial intelligence (AI) is rapidly affecting more aspects of our lives as a result of significant advancements in its research and the widespread usage of interactive technologies. This has led to the birth of several new social phenomena. Many nations have been working to comprehend these phenomena and discover solutions for moving artificial intelligence development in the proper direction to benefit individuals and communities at large. These efforts necessitate multidisciplinary approaches, encompassing not only the scientific fields involved in the creation of artificial intelligence and human–computer interaction but also strong collaboration between academics and practitioners. Because of this, the primary objective of the MIDI conference, which was conducted online on December 13–15, 2022, is to combine two up until recently distinct disciplines of research—artificial intelligence and human–technology interaction.

Published
2023
Full Text
View/download PDF

32. Mix-and-extrude: high-viscosity sample injection towards time-resolved protein crystallography

Author

Vakili, Mohammad, primary, Han, Huijong, additional, Schmidt, Christina, additional, Wrona, Agnieszka, additional, Kloos, Marco, additional, de Diego, Iñaki, additional, Dörner, Katerina, additional, Geng, Tian, additional, Kim, Chan, additional, Koua, Faisal H. M., additional, Melo, Diogo V. M., additional, Rappas, Mathieu, additional, Round, Adam, additional, Round, Ekaterina, additional, Sikorski, Marcin, additional, Valerio, Joana, additional, Zhou, Tiankun, additional, Lorenzen, Kristina, additional, and Schulz, Joachim, additional

Published
2023
Full Text
View/download PDF

35. More Just Measure of Fairness for Sharing Network Resources

Author

Nowicki, Krzysztof, Malinowski, Aleksander, Sikorski, Marcin, Diniz Junqueira Barbosa, Simone, Series editor, Chen, Phoebe, Series editor, Du, Xiaoyong, Series editor, Filipe, Joaquim, Series editor, Kara, Orhun, Series editor, Liu, Ting, Series editor, Kotenko, Igor, Series editor, Sivalingam, Krishna M., Series editor, Washio, Takashi, Series editor, Gaj, Piotr, editor, Kwiecień, Andrzej, editor, and Stera, Piotr, editor

Published
2016
Full Text
View/download PDF

37. Vibrational wavepacket dynamics in Fe carbene photosensitizer determined with femtosecond X-ray emission and scattering

Author

Kunnus, Kristjan, Vacher, Morgane, Harlang, Tobias C. B., Kjær, Kasper S., Haldrup, Kristoffer, Biasin, Elisa, van Driel, Tim B., Pápai, Mátyás, Chabera, Pavel, Liu, Yizhu, Tatsuno, Hideyuki, Timm, Cornelia, Källman, Erik, Delcey, Mickaël, Hartsock, Robert W., Reinhard, Marco E., Koroidov, Sergey, Laursen, Mads G., Hansen, Frederik B., Vester, Peter, Christensen, Morten, Sandberg, Lise, Németh, Zoltán, Szemes, Dorottya Sárosiné, Bajnóczi, Éva, Alonso-Mori, Roberto, Glownia, James M., Nelson, Silke, Sikorski, Marcin, Sokaras, Dimosthenis, Lemke, Henrik T., Canton, Sophie E., Møller, Klaus B., Nielsen, Martin M., Vankó, György, Wärnmark, Kenneth, Sundström, Villy, Persson, Petter, Lundberg, Marcus, Uhlig, Jens, and Gaffney, Kelly J.

Published
2020
Full Text
View/download PDF

38. Can Evaluation Patterns Enable End Users to Evaluate the Quality of an e-learning System? An Exploratory Study

Author

Ardito, Carmelo, Lanzilotti, Rosa, Sikorski, Marcin, Garnik, Igor, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Kobsa, Alfred, editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Weikum, Gerhard, editor, Stephanidis, Constantine, editor, and Antona, Margherita, editor

Published
2014
Full Text
View/download PDF

39. Megahertz serial crystallography

Author

Wiedorn, Max O., Oberthür, Dominik, Bean, Richard, Schubert, Robin, Werner, Nadine, Abbey, Brian, Aepfelbacher, Martin, Adriano, Luigi, Allahgholi, Aschkan, Al-Qudami, Nasser, Andreasson, Jakob, Aplin, Steve, Awel, Salah, Ayyer, Kartik, Bajt, Saša, Barák, Imrich, Bari, Sadia, Bielecki, Johan, Botha, Sabine, Boukhelef, Djelloul, Brehm, Wolfgang, Brockhauser, Sandor, Cheviakov, Igor, Coleman, Matthew A., Cruz-Mazo, Francisco, Danilevski, Cyril, Darmanin, Connie, Doak, R. Bruce, Domaracky, Martin, Dörner, Katerina, Du, Yang, Fangohr, Hans, Fleckenstein, Holger, Frank, Matthias, Fromme, Petra, Gañán-Calvo, Alfonso M., Gevorkov, Yaroslav, Giewekemeyer, Klaus, Ginn, Helen Mary, Graafsma, Heinz, Graceffa, Rita, Greiffenberg, Dominic, Gumprecht, Lars, Göttlicher, Peter, Hajdu, Janos, Hauf, Steffen, Heymann, Michael, Holmes, Susannah, Horke, Daniel A., Hunter, Mark S., Imlau, Siegfried, Kaukher, Alexander, Kim, Yoonhee, Klyuev, Alexander, Knoška, Juraj, Kobe, Bostjan, Kuhn, Manuela, Kupitz, Christopher, Küpper, Jochen, Lahey-Rudolph, Janine Mia, Laurus, Torsten, Le Cong, Karoline, Letrun, Romain, Xavier, P. Lourdu, Maia, Luis, Maia, Filipe R. N. C., Mariani, Valerio, Messerschmidt, Marc, Metz, Markus, Mezza, Davide, Michelat, Thomas, Mills, Grant, Monteiro, Diana C. F., Morgan, Andrew, Mühlig, Kerstin, Munke, Anna, Münnich, Astrid, Nette, Julia, Nugent, Keith A., Nuguid, Theresa, Orville, Allen M., Pandey, Suraj, Pena, Gisel, Villanueva-Perez, Pablo, Poehlsen, Jennifer, Previtali, Gianpietro, Redecke, Lars, Riekehr, Winnie Maria, Rohde, Holger, Round, Adam, Safenreiter, Tatiana, Sarrou, Iosifina, Sato, Tokushi, Schmidt, Marius, Schmitt, Bernd, Schönherr, Robert, Schulz, Joachim, Sellberg, Jonas A., Seibert, M. Marvin, Seuring, Carolin, Shelby, Megan L., Shoeman, Robert L., Sikorski, Marcin, Silenzi, Alessandro, Stan, Claudiu A., Shi, Xintian, Stern, Stephan, Sztuk-Dambietz, Jola, Szuba, Janusz, Tolstikova, Aleksandra, Trebbin, Martin, Trunk, Ulrich, Vagovic, Patrik, Ve, Thomas, Weinhausen, Britta, White, Thomas A., Wrona, Krzysztof, Xu, Chen, Yefanov, Oleksandr, Zatsepin, Nadia, Zhang, Jiaguo, Perbandt, Markus, Mancuso, Adrian P., Betzel, Christian, Chapman, Henry, and Barty, Anton

Published
2018
Full Text
View/download PDF

40. Automatic bad-pixel mask maker for X-ray pixel detectors with application to serial crystallography

Author

Sadri, Alireza, primary, Hadian-Jazi, Marjan, additional, Yefanov, Oleksandr, additional, Galchenkova, Marina, additional, Kirkwood, Henry, additional, Mills, Grant, additional, Sikorski, Marcin, additional, Letrun, Romain, additional, de Wijn, Raphael, additional, Vakili, Mohammad, additional, Oberthuer, Dominik, additional, Komadina, Dana, additional, Brehm, Wolfgang, additional, Mancuso, Adrian P., additional, Carnis, Jerome, additional, Gelisio, Luca, additional, and Chapman, Henry N., additional

Published
2022
Full Text
View/download PDF

43. Knowledge Management Challenges in Collaborative Design of a Virtual Call Centre

Author

Sikorski, Marcin, Garnik, Igor, Ludwiszewski, Bohdan, Wyrwiński, Jan, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, Goebel, Randy, editor, Siekmann, Jörg, editor, Wahlster, Wolfgang, editor, König, Andreas, editor, Dengel, Andreas, editor, Hinkelmann, Knut, editor, Kise, Koichi, editor, Howlett, Robert J., editor, and Jain, Lakhmi C., editor

Published
2011
Full Text
View/download PDF

44. Towards real-time analysis of liquid jet alignment in serial femtosecond crystallography

Author

Patel, Jaydeep, primary, Round, Adam, additional, Bielecki, Johan, additional, Doerner, Katerina, additional, Kirkwood, Henry, additional, Letrun, Romain, additional, Schulz, Joachim, additional, Sikorski, Marcin, additional, Vakili, Mohammad, additional, de Wijn, Raphael, additional, Peele, Andrew, additional, Mancuso, Adrian P., additional, and Abbey, Brian, additional

Published
2022
Full Text
View/download PDF

45. Pump–probe capabilities at the SPB/SFX instrument of the European XFEL

Author

Koliyadu, Jayanath C. P., primary, Letrun, Romain, additional, Kirkwood, Henry J., additional, Liu, Jia, additional, Jiang, Man, additional, Emons, Moritz, additional, Bean, Richard, additional, Bellucci, Valerio, additional, Bielecki, Johan, additional, Birnsteinova, Sarlota, additional, de Wijn, Raphael, additional, Dietze, Thomas, additional, E, Juncheng, additional, Grünert, Jan, additional, Kane, Daniel, additional, Kim, Chan, additional, Kim, Yoonhee, additional, Lederer, Max, additional, Manning, Bradley, additional, Mills, Grant, additional, Morillo, Luis L., additional, Reimers, Nadja, additional, Rompotis, Dimitrios, additional, Round, Adam, additional, Sikorski, Marcin, additional, Takem, Cedric M. S., additional, Vagovič, Patrik, additional, Venkatesan, Sandhya, additional, Wang, Jinxiong, additional, Wegner, Ulrike, additional, Mancuso, Adrian P., additional, and Sato, Tokushi, additional

Published
2022
Full Text
View/download PDF

46. Beyond the User Interface: Towards User-Centred Design of Online Services

Author

Sikorski, Marcin, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, and Jacko, Julie A., editor

Published
2009
Full Text
View/download PDF

47. Digital Interaction and Machine Intelligence

Author

Biele, Cezary, Kacprzyk, Janusz, Kopeć, Wiesław, Owsiński, Jan W., Romanowski, Andrzej, and Sikorski, Marcin

Subjects
Computational Intelligence, AI, MIDI 2021, MIDI, Machine Intelligence, Digital Interaction, bic Book Industry Communication::U Computing & information technology::UY Computer science::UYQ Artificial intelligence, bic Book Industry Communication::U Computing & information technology::UN Databases, bic Book Industry Communication::U Computing & information technology::UY Computer science::UYQ Artificial intelligence::UYQM Machine learning
Abstract

This book is open access, which means that you have free and unlimited access. This book presents the Proceedings of the 9th Machine Intelligence and Digital Interaction Conference. Significant progress in the development of artificial intelligence (AI) and its wider use in many interactive products are quickly transforming further areas of our life, which results in the emergence of various new social phenomena. Many countries have been making efforts to understand these phenomena and find answers on how to put the development of artificial intelligence on the right track to support the common good of people and societies. These attempts require interdisciplinary actions, covering not only science disciplines involved in the development of artificial intelligence and human-computer interaction but also close cooperation between researchers and practitioners. For this reason, the main goal of the MIDI conference held on 9-10.12.2021 as a virtual event is to integrate two, until recently, independent fields of research in computer science: broadly understood artificial intelligence and human-technology interaction.

Published
2022
Full Text
View/download PDF

48. HCI and the Economics of User Experience

Author

Sikorski, Marcin, Karat, John, editor, Vanderdonckt, Jean, editor, Abowd, Gregory, editor, Calvary, Gaëlle, editor, Carroll, John, editor, Cockton, Gilbert, editor, Czerwinski, Mary, editor, Feiner, Steve, editor, Furtado, Elizabeth, editor, Höök, Kristiana, editor, Jacob, Robert, editor, Jeffries, Robin, editor, Johnson, Peter, editor, Nakakoji, Kumiyo, editor, Palanque, Philippe, editor, Pastor, Oscar, editor, Paternò, Fabio, editor, Pribeanu, Costin, editor, Salzman, Marilyn, editor, Schmandt, Chris, editor, Stolze, Markus, editor, Szwillus, Gerd, editor, Tscheligi, Manfred, editor, Veer, Gerrit van der, editor, Zhai, Schumin, editor, Law, Effie Lai-Chong, editor, and Hvannberg, Ebba Thora, editor

Published
2008
Full Text
View/download PDF

49. Coherent X-rays reveal the influence of cage effects on ultrafast water dynamics

Author

Perakis, Fivos, Camisasca, Gaia, Lane, Thomas J., Späh, Alexander, Wikfeldt, Kjartan Thor, Sellberg, Jonas A., Lehmkühler, Felix, Pathak, Harshad, Kim, Kyung Hwan, Amann-Winkel, Katrin, Schreck, Simon, Song, Sanghoon, Sato, Takahiro, Sikorski, Marcin, Eilert, Andre, McQueen, Trevor, Ogasawara, Hirohito, Nordlund, Dennis, Roseker, Wojciech, Koralek, Jake, Nelson, Silke, Hart, Philip, Alonso-Mori, Roberto, Feng, Yiping, Zhu, Diling, Robert, Aymeric, Grübel, Gerhard, Pettersson, Lars G. M., and Nilsson, Anders

Published
2018
Full Text
View/download PDF

50. Unsupervised learning approaches to characterizing heterogeneous samples using X-ray single-particle imaging

Author

Zhuang, Yulong, Awel, Salah, Barty, Anton, Bean, Richard, Bielecki, Johan, Bergemann, Martin, Daurer, Benedikt J., Ekeberg, Tomas, Estillore, Armando D., Fangohr, Hans, Giewekemeyer, Klaus, Hunter, Mark S., Karnevskiy, Mikhail, Kirian, Richard A., Kirkwood, Henry, Kim, Yoonhee, Koliyadu, Jayanath, Lange, Holger, Letrun, Romain, Luebke, Jannik, Mall, Abhishek, Michelat, Thomas, Morgan, Andrew J., Roth, Nils, Samanta, Amit K., Sato, Tokushi, Shen, Zhou, Sikorski, Marcin, Schulz, Florian, Spence, John C. H., Vagovic, Patrik, Wollweber, Tamme, Worbs, Lena, Xavier, P. Lourdu, Yefanov, Oleksandr, Maia, Filipe, Horke, Daniel A., Küpper, Jochen, Loh, N. Duane, Mancuso, Adrian P., Chapman, Henry N., Ayyer, Kartik, Zhuang, Yulong, Awel, Salah, Barty, Anton, Bean, Richard, Bielecki, Johan, Bergemann, Martin, Daurer, Benedikt J., Ekeberg, Tomas, Estillore, Armando D., Fangohr, Hans, Giewekemeyer, Klaus, Hunter, Mark S., Karnevskiy, Mikhail, Kirian, Richard A., Kirkwood, Henry, Kim, Yoonhee, Koliyadu, Jayanath, Lange, Holger, Letrun, Romain, Luebke, Jannik, Mall, Abhishek, Michelat, Thomas, Morgan, Andrew J., Roth, Nils, Samanta, Amit K., Sato, Tokushi, Shen, Zhou, Sikorski, Marcin, Schulz, Florian, Spence, John C. H., Vagovic, Patrik, Wollweber, Tamme, Worbs, Lena, Xavier, P. Lourdu, Yefanov, Oleksandr, Maia, Filipe, Horke, Daniel A., Küpper, Jochen, Loh, N. Duane, Mancuso, Adrian P., Chapman, Henry N., and Ayyer, Kartik

Abstract

One of the outstanding analytical problems in X-ray single-particle imaging (SPI) is the classification of structural heterogeneity, which is especially difficult given the low signal-to-noise ratios of individual patterns and the fact that even identical objects can yield patterns that vary greatly when orientation is taken into consideration. Proposed here are two methods which explicitly account for this orientation-induced variation and can robustly determine the structural landscape of a sample ensemble. The first, termed common-line principal component analysis (PCA), provides a rough classification which is essentially parameter free and can be run automatically on any SPI dataset. The second method, utilizing variation auto-encoders (VAEs), can generate 3D structures of the objects at any point in the structural landscape. Both these methods are implemented in combination with the noise-tolerant expand-maximizecompress (EMC) algorithm and its utility is demonstrated by applying it to an experimental dataset from gold nanoparticles with only a few thousand photons per pattern. Both discrete structural classes and continuous deformations are recovered. These developments diverge from previous approaches of extracting reproducible subsets of patterns from a dataset and open up the possibility of moving beyond the study of homogeneous sample sets to addressing open questions on topics such as nanocrystal growth and dynamics, as well as phase transitions which have not been externally triggered.

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results