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4. eHealth to Improve Psychological Functioning and Self-Management of People With Chronic Kidney Disease:A Randomized Controlled Trial

Author

Cardol, Cinderella K., Van Middendorp, Henriët, Dusseldorp, Elise, Van Der Boog, Paul J.M., Hilbrands, Luuk B., Navis, Gerjan, Sijpkens, Yvo W.J., Evers, Andrea W.M., Van Dijk, Sandra, Cardol, Cinderella K., Van Middendorp, Henriët, Dusseldorp, Elise, Van Der Boog, Paul J.M., Hilbrands, Luuk B., Navis, Gerjan, Sijpkens, Yvo W.J., Evers, Andrea W.M., and Van Dijk, Sandra

Abstract

Objective Psychological distress is common among patients with chronic kidney disease and can interfere with disease self-management. We assessed the effectiveness of the personalized E-GOAL electronic health care pathway with screening and cognitive-behavioral therapy including self-management support, aimed to treat psychological distress and facilitate self-management among people with chronic kidney disease not on dialysis (N = 121). Methods Primary outcome of the open two-arm parallel randomized controlled trial in four Dutch hospitals was psychological distress at posttest directly after the intervention and at 3-month follow-up. Secondary outcomes were physical and mental health-related quality of life, self-efficacy, chronic disease self-management, and personalized outcomes, that is, perceived progress compared with the previous time point on functioning (e.g., mood or social functioning) and self-management (e.g., dietary or medication adherence) outcomes that were prioritized by each individual. Results Linear mixed-effects analyses showed no significant time-by-group interaction effects for psychological distress, health-related quality of life, self-efficacy, and chronic condition self-management, whereas analyses of covariance showed significantly more perceived progress in the intervention group at posttest on personally prioritized areas of functioning (b = 0.46, 95% confidence interval = 0.07-0.85) and self-management (b = 0.55, 95% confidence interval = 0.16-0.95), with Cohen d values of 0.46 and 0.54 (medium effects), respectively. Effects on personalized outcomes were maintained at follow-up. Conclusions Compared with regular care only, the electronic health intervention did not reduce psychological distress, whereas personalized outcomes did improve significantly after intervention. Future studies could consider personalized outcomes that reflect individually relevant areas and treatment goals, matching person-tailored treatments.

Published
2023

5. eHealth to Improve Psychological Functioning and Self-Management of People With Chronic Kidney Disease: A Randomized Controlled Trial

Author

Cardol, Cinderella K. (author), van Middendorp, Henriët (author), Dusseldorp, Elise (author), van der Boog, Paul J.M. (author), Hilbrands, Luuk B. (author), Navis, Gerjan (author), Sijpkens, Yvo W.J. (author), Evers, A.W.M. (author), van Dijk, Sandra (author), Cardol, Cinderella K. (author), van Middendorp, Henriët (author), Dusseldorp, Elise (author), van der Boog, Paul J.M. (author), Hilbrands, Luuk B. (author), Navis, Gerjan (author), Sijpkens, Yvo W.J. (author), Evers, A.W.M. (author), and van Dijk, Sandra (author)

Abstract

Objective Psychological distress is common among patients with chronic kidney disease and can interfere with disease self-management. We assessed the effectiveness of the personalized E-GOAL electronic health care pathway with screening and cognitive-behavioral therapy including self-management support, aimed to treat psychological distress and facilitate self-management among people with chronic kidney disease not on dialysis (N = 121). Methods Primary outcome of the open two-arm parallel randomized controlled trial in four Dutch hospitals was psychological distress at posttest directly after the intervention and at 3-month follow-up. Secondary outcomes were physical and mental health-related quality of life, self-efficacy, chronic disease self-management, and personalized outcomes, that is, perceived progress compared with the previous time point on functioning (e.g., mood or social functioning) and self-management (e.g., dietary or medication adherence) outcomes that were prioritized by each individual. Results Linear mixed-effects analyses showed no significant time-by-group interaction effects for psychological distress, health-related quality of life, self-efficacy, and chronic condition self-management, whereas analyses of covariance showed significantly more perceived progress in the intervention group at posttest on personally prioritized areas of functioning (b = 0.46, 95% confidence interval = 0.07-0.85) and self-management (b = 0.55, 95% confidence interval = 0.16-0.95), with Cohen d values of 0.46 and 0.54 (medium effects), respectively. Effects on personalized outcomes were maintained at follow-up. Conclusions Compared with regular care only, the electronic health intervention did not reduce psychological distress, whereas personalized outcomes did improve significantly after intervention. Future studies could consider personalized outcomes that reflect individually relevant areas and treatment goals, matching person-tailored treatments., Applied Ergonomics and Design

Published
2023
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6. eHealth to Improve Psychological Functioning and Self-Management of People With Chronic Kidney Disease: A Randomized Controlled Trial

Author

Cardol, Cinderella K., van Middendorp, Henriët, Dusseldorp, Elise, van der Boog, Paul J.M., Hilbrands, Luuk B., Navis, Gerjan, Sijpkens, Yvo W.J., Evers, A.W.M., van Dijk, Sandra, Health Economics (HE), Value, Affordability and Sustainability (VALUE), and Groningen Kidney Center (GKC)

Subjects
self-management, patient-tailored care, psychological distress, SDG 3 - Good Health and Well-being, randomized controlled trial, eHealth, chronic kidney disease
Abstract

Objective Psychological distress is common among patients with chronic kidney disease and can interfere with disease self-management. We assessed the effectiveness of the personalized E-GOAL electronic health care pathway with screening and cognitive-behavioral therapy including self-management support, aimed to treat psychological distress and facilitate self-management among people with chronic kidney disease not on dialysis (N = 121). Methods Primary outcome of the open two-arm parallel randomized controlled trial in four Dutch hospitals was psychological distress at posttest directly after the intervention and at 3-month follow-up. Secondary outcomes were physical and mental health-related quality of life, self-efficacy, chronic disease self-management, and personalized outcomes, that is, perceived progress compared with the previous time point on functioning (e.g., mood or social functioning) and self-management (e.g., dietary or medication adherence) outcomes that were prioritized by each individual. Results Linear mixed-effects analyses showed no significant time-by-group interaction effects for psychological distress, health-related quality of life, self-efficacy, and chronic condition self-management, whereas analyses of covariance showed significantly more perceived progress in the intervention group at posttest on personally prioritized areas of functioning (b = 0.46, 95% confidence interval = 0.07-0.85) and self-management (b = 0.55, 95% confidence interval = 0.16-0.95), with Cohen d values of 0.46 and 0.54 (medium effects), respectively. Effects on personalized outcomes were maintained at follow-up. Conclusions Compared with regular care only, the electronic health intervention did not reduce psychological distress, whereas personalized outcomes did improve significantly after intervention. Future studies could consider personalized outcomes that reflect individually relevant areas and treatment goals, matching person-tailored treatments.

Published
2023

8. A randomized comparison of 1-h sodium bicarbonate hydration versus standard peri-procedural saline hydration in patients with chronic kidney disease undergoing intravenous contrast-enhanced computerized tomography

Author

Kooiman, Judith, Sijpkens, Yvo W.J., de Vries, Jean-Paul P.M., Brulez, Harald F.H., Hamming, Jaap F., van der Molen, Aart J., Aarts, Nico J.M., Cannegieter, Suzanne C., Putter, Hein, Swarts, Renate, van den Hout, Wilbert B., Rabelink, Ton J., and Huisman, Menno V.

Published
2014
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9. Reply to letter to the editor by Koza et al

Author

Kooiman, Judith, le Haen, Pum A., Gezgin, Gülcin, de Vries, Jean-Paul P.M., Boersma, D, Brulez, Harald F.H., Sijpkens, Yvo W.J., van der Molen, Aart J., Cannegieter, Suzanne C., Hamming, Jaap F., and Huisman, Menno V.

Published
2013
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10. Validation of the kidney failure risk equation in European CKD patients

Author

Peeters, Mieke J., van Zuilen, Arjan D., van den Brand, Jan A.J.G., Bots, Michiel L., Blankestijn, Peter J., Wetzels, Jack F.M., Blankestijn, Peter J., Bots, Michiel L., van Buren, Marjolijn, ten Dam, Marc A.G.J., Kaasjager, Karin A.H., Ligtenberg, Gerry, Sijpkens, Yvo W.J., Henk E., Sluiter, van de Ven, Peter J.G., Vervoort, Gerald, Vleming, Louis-Jean, Wetzels, Jack F.M., and van Zuilen, Arjan D.

Published
2013
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18. Fataal hersenoedeem bij behandeling van een volwassene met diabetische ketoacidose

Author

Dekker, Tim J.A., Janson, Jeroen A., Hoorn, Ewout J., Sijpkens, Yvo W.J., and Internal Medicine

Subjects
SDG 3 - Good Health and Well-being
Abstract

Diabetic ketoacidosis is relatively common, but the optimal treatment of this condition is still controversial. Cerebral oedema is a rare, but potentially fatal complication. We present the case of an adult patient who presented with de novo diabetic ketoacidosis that was complicated by cerebral oedema during treatment. In this article we discuss factors that may have played a role in the development of this complication. A prolonged hyperosmolar state in diabetic ketoacidosis may increase the risk of cerebral oedema as a result of cerebral compensatory mechanisms. In this group of patients, liberal doses of insulin, fluids and bicarbonate may lead to a decrease in the effective serum osmolarity which can lead to water shifts in the cerebrum. We suggest several adjustments to current treatment guidelines for patients with diabetic ketoacidosis who have undergone a prolonged period of hyperosmolar derangement, with the aim of decreasing the risk of cerebral oedema.

Published
2017

20. Nurse Practitioner Care Improves Renal Outcome in Patients with CKD

Author

Peeters, Mieke J., primary, van Zuilen, Arjan D., additional, van den Brand, Jan A.J.G., additional, Bots, Michiel L., additional, van Buren, Marjolijn, additional, ten Dam, Marc A.G.J., additional, Kaasjager, Karin A.H., additional, Ligtenberg, Gerry, additional, Sijpkens, Yvo W.J., additional, Sluiter, Henk E., additional, van de Ven, Peter J.G., additional, Vervoort, Gerald, additional, Vleming, Louis-Jean, additional, Blankestijn, Peter J., additional, and Wetzels, Jack F.M., additional

Published
2014
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21. Multifactorial intervention with nurse practitioners does not change cardiovascular outcomes in patients with chronic kidney disease

Author

van Zuilen, Arjan D., primary, Bots, Michiel L., additional, Dulger, Arzu, additional, van der Tweel, Ingeborg, additional, van Buren, Marjolijn, additional, ten Dam, Marc A.G.J., additional, Kaasjager, Karin A.H., additional, Ligtenberg, Gerry, additional, Sijpkens, Yvo W.J., additional, Sluiter, Henk E., additional, van de Ven, Peter J.G., additional, Vervoort, Gerald, additional, Vleming, Louis-Jean, additional, Blankestijn, Peter J., additional, and Wetzels, Jack F.M., additional

Published
2012
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28. Proteinuria as a Risk Marker for the Progression of Chronic Kidney Disease in Patients on Predialysis Care and the Role of Angiotensin-Converting Enzyme Inhibitor/Angiotensin II Receptor Blocker Treatment.

Author

de Goeij, Moniek C.M., Liem, Madieke, de Jager, Dinanda J., Voormolen, Nora, Sijpkens, Yvo W.J., Rotmans, Joris I., Boeschoten, Elisabeth W., Dekker, Friedo W., Grootendorst, Diana C., and Halbesma, Nynke

Subjects
PROTEINURIA, KIDNEY diseases, ANGIOTENSIN converting enzyme, ANGIOTENSIN II, DISEASE progression, HEALTH outcome assessment
Abstract

Background/Aims: Proteinuria is a risk marker for progression of chronic kidney disease (CKD) and treatment with an angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker (ACEi/ARB) is beneficial in these patients. However, little is known about proteinuria and ACEi/ARB treatment in patients on specialized predialysis care. Therefore, we investigated the association of urinary protein excretion (UPE) and ACEi/ARB treatment with renal function decline (RFD) and/or the start of renal replacement therapy (RRT) in patients on predialysis care. Methods: In the PREPARE-1 cohort, 547 incident predialysis patients (CKD stages IV-V), referred as part of the usual care to outpatient clinics of eight Dutch hospitals, were included (1999-2001) and followed until the start of RRT, mortality, or January 1, 2008. The main outcomes were rate of RFD, estimated as the slope of available eGFR measurements, and the start of RRT. Results: Patients with mild proteinuria (>0.3 to ≤1.0 g/24 h) had an adjusted additional RFD of 0.35 ml/min/1.73 m2/month (95% CI: 0.01; 0.68) and a higher rate of starting RRT [adjusted HR: 1.70 (1.05; 2.77)] compared with patients without proteinuria (≤0.3 g/24 h). With every consecutive UPE category (>1.0 to ≤3.0, >3.0 to ≤6.0, and >6.0 g/24 h), RFD accelerated and the start of RRT was earlier. Furthermore, patients starting (n = 16) or continuing (n = 133) treatment with ACEi/ARBs during predialysis care had a lower rate of starting RRT compared with patients not using treatment [n = 152, adjusted HR: 0.56 (0.29; 1.08) and 0.90 (0.68; 1.20), respectively]. Conclusion: In patients on predialysis care, we confirmed that proteinuria is a risk marker for the progression of CKD. Furthermore, no evidence was present that the use of ACEi/ARBs is deleterious. Copyright © 2012 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]

Published
2012
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29. Association of Blood Pressure with the Start of Renal Replacement Therapy in Elderly Compared with Young Patients Receiving Predialysis Care.

Author

de Goeij, Moniek C.M., de Jager, Dinanda J., Grootendorst, Diana C., Voormolen, Nora, Sijpkens, Yvo W.J., van Dijk, Sandra, Hoogeveen, Ellen K., Kooman, Jeroen P., Boeschoten, Elisabeth W., Dekker, Friedo W., and Halbesma, Nynke

Subjects
SYSTOLIC blood pressure, KIDNEY disease treatments, DISEASES in older people, ACE inhibitors, ANGIOTENSIN receptors, PROPORTIONAL hazards models
Abstract

BackgroundIn the growing elderly predialysis population, little is known about the effect of identified risk factors on the progression to end-stage renal disease. Therefore, we investigated the association of systolic (SBP) and diastolic blood pressure (DBP) with the start of renal replacement therapy (RRT), in elderly (≥65 years) compared with young (<65 years) predialysis patients.MethodsIn the PREPARE-1 cohort, 547 incident predialysis patients, referred as part of the usual care to eight Dutch predialysis care outpatient clinics, were included (1999-2001) and followed until the start of dialysis, transplantation, death, or until 1 January 2008. The outcome was the start of RRT. All analyses were stratified for age; <65 years (young) and ≥65 years (elderly).ResultsIn young predialysis patients (n = 268) higher SBP (every 20 mm Hg increase) and high DBP (DBP ≥100 mm Hg compared with 80-89 mm Hg) were associated with a higher rate of starting RRT (adjusted hazard ratio (HR) (95% confidence interval) 1.21 (1.09;1.34) and 1.74 (1.16;2.62), respectively). However, in elderly predialysis patients (n = 240) only patients with SBP ≥180 mm Hg had an increased rate compared with patients with 140-159 mm Hg (adjusted HR 2.33 (1.41;3.87)). Furthermore, patients with DBP <70 or ≥100 mm Hg had an increased rate of starting RRT, independent of SBP, compared with patients with 80-89 mm Hg (fully adjusted HR 1.72 (1.01;2.94) and 2.05 (1.13;3.73), respectively).ConclusionsThe association of SBP and DBP with the start of RRT is different between elderly and young predialysis patients.American Journal of Hypertension 2012; doi:10.1038/ajh.2012.100 [ABSTRACT FROM AUTHOR]

Published
2012
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