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Extramedullary masses as features of acute monoblastic leukemia are rare. Acute monoblastic leukemia is an uncommon type of nonlymphocytic leukemia that generally first manifest with signs and of bone marrow failure, articular and/or neurological symptoms. This study describes one patient with acute monoblastic leukemia in whom the initial manifestation of the disorder was related to testicular mass.

The retroperitoneal primitive tumors are rare and the majority are malignant. Frequently the preoperative diagnosis is difficult because they show many clinical symptoms depending on the organs involved. A case of primitive retroperitoneal tumor with left varicocele syndrome as a first clinical manifestation is described.

The adenocarcinoma is a rare istologic type of bladder cancer. A particular subset, the "signet ring cell carcinoma", can have the clinical expression of bladder linitis plastica. In the metastatic form this evenience is very rare and only two cases are reported in the literature. The Authors describe third case.

Fourteen patients with advanced bladder cancer T3 to T4, N1 to N2 positive, were treated with reductive surgery (tumorectomy) and systemic adjuvant polychemotherapy (M-VAC: methotrexate 30 mg/m2, vinblastine 3 mg/m2, adriamycin 30 mg/m2 and cis-platin 70 mg/m2) in the period from December 1985 to December 1987. The aim of this combination was to preserve detrusor function in order to give tha patients a better "quality of life". After a follow-up varying from 12-24 months, complete clinical remission for 18 months was observed in 2 patients, the remainder showed an improvement of the performance status compared with those treated by conventional therapy (radical cystectomy and/or radiotherapy) but no changes in overall survival was achieved.