1. Diagnostic and therapeutic workup of erectile dysfunction: results from a delphi consensus of andrology experts
- Author
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Isidori, A. M., Giammusso, B., Corona, G., Verze, P., Albanesi, L., Antomarchi, F., Arcaniolo, D., Balercia, G., Barbonetti, A., Barletta, D., Barrese, F., Bellastella, G., Biggio, A., Bitelli, M., Botturi, A., Brancato, T., Branchina, A., Cai, T., Canale, D., Capone, L., Capone, M., Carluccini, A., Citarrella, R., Cocci, A., Corvese, F., Cozza, P. P., Creta, M., D'Andrea, S., Dalena, G., Damiano, R., Defeudis, G., Del Grasso, A., Delbarba, A., Delle Rose, A., Di Crosta, G., Filippo, Di, Di Lena, S., Di Martino, M., Di Millo, F., Di Palma, P., Diazzi, D., Dicuio, M., Diosi, D., Fabbri, A., Fattorini, G., Florio, M., Formiconi, A., Franco, G., Galdiero, M., Giambersio, A. M., Gianfrilli, D., Giovannone, R., Granata, A. M., Iafrate, M., Iapicca, G., Iatrino, G., Ilacqua, N., Innocenti, F., Italiano, E., Izzo, A., Izzo, P., Lamartina, M., Ledda, A. F., Lepri, L., C. F., Lo, Lombardo, F., Luca, G., Macchione, L., Maga, T., Matteo, M., Malvestiti, G. M., Marella, G., Maretti, C., Maturo, G., Mazzaferro, D., Mazzilli, R., Migliorini, F., Milardi, D., Minardi, V., Moiso, A., Mondaini, N., Moretti, M., Motta, G., Nerva, F., Pastore, A. L., Paulis, G., Piazza, N., Pili, M., Pistone, A., Pivonello, R., Pizzocaro, A., Polverini, M., Provinzano, V., Rastrelli, G., Risi, O., Rocchegiani, A., Rolle, L., Romanelli, F., Romano, G., Russo, G. I., Salemi, G., Salzano, C., Sanna, F., Sansone, A., Santi, D., Scalese, G. A., Scarano, P., Scroppo, F. I., Serrao, M. F., Sidoti, G., Silvestre, G., Simone, O., Sorrentino, M., Tallis, V., Tammaro, R., Ughi, G., Vagnoni, V., Vavallo, A., Vecchio, D., Vita, A., Zicarelli, P., and Zucchi, A.
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Consensus ,erectile dysfunction ,Urology ,Endocrinology, Diabetes and Metabolism ,media_common.quotation_subject ,education ,030232 urology & nephrology ,lcsh:Medicine ,Dermatology ,Delphi ,Consensus method ,Likert scale ,Andrology ,03 medical and health sciences ,Behavioral Neuroscience ,0302 clinical medicine ,Endocrinology ,Erectile Dysfunction ,PDE5 Inhibitors ,Treatment ,Voting ,medicine ,PDE5 inhibitors ,computer.programming_language ,media_common ,030219 obstetrics & reproductive medicine ,treatment ,business.industry ,lcsh:R ,lcsh:Other systems of medicine ,medicine.disease ,lcsh:RZ201-999 ,consensus ,delphi ,Phosphodiesterase Type 5 Inhibitors ,Clinical Practice ,Psychiatry and Mental health ,Erectile dysfunction ,Hot topics ,Reproductive Medicine ,business ,computer - Abstract
Introduction Erectile dysfunction is a highly prevalent condition. Existing guidelines provide recommendations for diagnosis and treatment, but they are often disregarded in clinical practice in favor of a “patient-tailored” approach. Objectives We planned a Delphi consensus method to bridge the gap between evidence-based medicine and the real-life approach in daily practice. Materials and Methods The Advisory Board prepared 15 statements on debated topics in andrology, each including 4–6 items designed as a 5-point Likert scale. After a validation phase, the questionnaire was sent by e-mail to a panel of experts for a first round of voting; members of the panel were later invited to a second round of voting, preceded by discussion of the “hot topics” identified in the first round. Results The first round of the Delphi consensus involved 101 experts; 71 (70%) also took part in the second round of voting. The Advisory Board deemed 22 items to be worthy of debate, and these underwent the second round of voting. “Real-life” results from the survey proved quite different from evidence-based recommendations. Conclusion Although guidelines suggest the best approach for a “standard” patient, real-life settings require flexibility. Diagnostic and therapeutic approaches should be tailored to the patients’ needs. Phosphodiesterase type 5 inhibitors are recognized as the first-line therapy in both settings, including the newly introduced sildenafil orodispersible film. Indications from the panel might help close the gap between recommendations from guidelines and real-life practice in relation to the diagnosis and treatment of erectile dysfunction.
- Published
- 2019