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1. Differential Effect of Targeted Temperature Management Between 32 °C and 36 °C Following Cardiac Arrest According to Initial Severity of Illness: Insights From Two International Data Sets

Author

Adnet, F., Agostinucci, J.M., Aissaoui-Balanant, N., Algalarrondo, V., Alla, F., Alonso, C., Amara, W., Annane, D., Antoine, C., Aubry, P., Azoulay, E., Beganton, F., Billon, C., Bougouin, W., Boutet, J., Bruel, C., Bruneval, P., Cariou, A., Carli, P., Casalino, E., Cerf, C., Chaib, A., Cholley, B., Cohen, Y., Combes, A., Coulaud, J.M., Da Silva, D., Das, V., Demoule, A., Denjoy, I., Deye, N., Diehl, J.L., Dinanian, S., Domanski, L., Dreyfuss, D., Dubois-Rande, J.L., Dumas, F., Duranteau, J., Empana, J.P., Extramiana, F., Fagon, J.Y., Fartoukh, M., Fieux, F., Gandjbakhch, E., Geri, G., Guidet, B., Halimi, F., Henry, P., Jabre, P., Joseph, L., Jost, D., Jouven, X., Karam, N., Lacotte, J., Lahlou-Laforet, K., Lamhaut, L., Lanceleur, A., Langeron, O., Lavergne, T., Lecarpentier, E., Leenhardt, A., Lellouche, N., Lemiale, V., Lemoine, F., Linval, F., Loeb, T., Ludes, B., Luyt, C.E., Mansencal, N., Mansouri, N., Marijon, E., Maury, E., Maxime, V., Megarbane, B., Mekontso-Dessap, A., Mentec, H., Mira, J.P., Monnet, X., Narayanan, K., Ngoyi, N., Perier, M.C., Piot, O., Plaisance, P., Plaud, B., Plu, I., Raphalen, J.H., Raux, M., Revaux, F., Ricard, J.D., Richard, C., Riou, B., Roussin, F., Santoli, F., Schortgen, F., Sharshar, T., Sideris, G., Spaulding, C., Teboul, J.L., Timsit, J.F., Tourtier, J.P., Tuppin, P., Ursat, C., Varenne, O., Vieillard-Baron, A., Voicu, S., Wahbi, K., Waldmann, V., Lascarrou, Jean Baptiste, Dumas, Florence, Bougouin, Wulfran, Legriel, Stephane, Aissaoui, Nadia, Deye, Nicolas, Beganton, Frankie, Lamhaut, Lionel, Jost, Daniel, Vieillard-Baron, Antoine, Nichol, Graham, Marijon, Eloi, Jouven, Xavier, and Cariou, Alain

Published
2023
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3. Should We Perform an Immediate Coronary Angiogram in All Patients After Cardiac Arrest?: Insights From a Large French Registry

Author

Adnet, F., Agostinucci, J.M., Aissaoui-Balanant, N., Albuisson, J., Algalarrondo, V., Alla, F., Annane, D., Antoine, C., Aubry, P., Azoulay, E., Beganton, F., Benhamou, D., Bougouin, W., Bruel, C., Cariou, A., Carli, P., Cerf, C., Chaib, A., Chastre, J., Cohen, Y., Combes, A., Cornaglia, C., Da Silva, D., Das, V., Demoule, A., Deye, N., Dhonneur, G., Diehl, J.L., Dinanian, S., Domanski, L., Dreyfuss, D., Duboc, D., Dubois-Rande, J.L., Dubourg, O., Duchateau, F.X., Dumas, F., Empana, J.P., Extramiana, F., Fagon, J.Y., Fartoukh, M., Fenioux, C., Fieux, F., Fraisse, F., Gabbas, M., Gandjbakhch, E., Guidet, B., Henry, P., Hidden Lucet, F., Jabre, P., Jacob, L., Joseph, L., Jost, D., Journois, D., Jouven, X., Karam, N., Kassim, H., Lahlou-Laforet, K., Lamhaut, L., Lanceleur, A., Langeron, O., Lanoe, V., Lecarpentier, E., Leenhardt, A., Lellouche, N., Lemiale, V., Linval, F., Loeb, T., Ludes, B., Maltret, A., Mansouri, N., Mantz, J., Marijon, E., Marty, J., Maury, E., Maxime, V., Mekontso-Dessaps, A., Mira, J.P., Monnet, X., Perier, M.C., Piot, O., Pirraccchio, R., Plu, I., Raux, M., Revaux, F., Ricard, J.D., Richard, C., Riou, B., Roussin, F., Santoli, F., Schortgen, F., Sharshar, T., Sideris, G., Spaulding, C., Teboul, J.L., Timsit, J.F., Tourtier, J.P., Tuppin, P., Ursat, C., Varenne, O., Vieillard-Baron, A., Voicu, S., Wahbi, K., Bougouin, Wulfran, Dumas, Florence, Karam, Nicole, Maupain, Carole, Marijon, Eloi, Lamhaut, Lionel, Jost, Daniel, Geri, Guillaume, Beganton, Frankie, Varenne, Olivier, Spaulding, Christian, Jouven, Xavier, and Cariou, Alain

Published
2018
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4. Differential Effect of Targeted Temperature Management Between 32 °C and 36 °C Following Cardiac Arrest According to Initial Severity of Illness

Author

Lascarrou, Jean Baptiste, primary, Dumas, Florence, additional, Bougouin, Wulfran, additional, Legriel, Stephane, additional, Aissaoui, Nadia, additional, Deye, Nicolas, additional, Beganton, Frankie, additional, Lamhaut, Lionel, additional, Jost, Daniel, additional, Vieillard-Baron, Antoine, additional, Nichol, Graham, additional, Marijon, Eloi, additional, Jouven, Xavier, additional, Cariou, Alain, additional, Adnet, F., additional, Agostinucci, J.M., additional, Aissaoui-Balanant, N., additional, Algalarrondo, V., additional, Alla, F., additional, Alonso, C., additional, Amara, W., additional, Annane, D., additional, Antoine, C., additional, Aubry, P., additional, Azoulay, E., additional, Beganton, F., additional, Billon, C., additional, Bougouin, W., additional, Boutet, J., additional, Bruel, C., additional, Bruneval, P., additional, Cariou, A., additional, Carli, P., additional, Casalino, E., additional, Cerf, C., additional, Chaib, A., additional, Cholley, B., additional, Cohen, Y., additional, Combes, A., additional, Coulaud, J.M., additional, Da Silva, D., additional, Das, V., additional, Demoule, A., additional, Denjoy, I., additional, Deye, N., additional, Diehl, J.L., additional, Dinanian, S., additional, Domanski, L., additional, Dreyfuss, D., additional, Dubois-Rande, J.L., additional, Dumas, F., additional, Duranteau, J., additional, Empana, J.P., additional, Extramiana, F., additional, Fagon, J.Y., additional, Fartoukh, M., additional, Fieux, F., additional, Gandjbakhch, E., additional, Geri, G., additional, Guidet, B., additional, Halimi, F., additional, Henry, P., additional, Jabre, P., additional, Joseph, L., additional, Jost, D., additional, Jouven, X., additional, Karam, N., additional, Lacotte, J., additional, Lahlou-Laforet, K., additional, Lamhaut, L., additional, Lanceleur, A., additional, Langeron, O., additional, Lavergne, T., additional, Lecarpentier, E., additional, Leenhardt, A., additional, Lellouche, N., additional, Lemiale, V., additional, Lemoine, F., additional, Linval, F., additional, Loeb, T., additional, Ludes, B., additional, Luyt, C.E., additional, Mansencal, N., additional, Mansouri, N., additional, Marijon, E., additional, Maury, E., additional, Maxime, V., additional, Megarbane, B., additional, Mekontso-Dessap, A., additional, Mentec, H., additional, Mira, J.P., additional, Monnet, X., additional, Narayanan, K., additional, Ngoyi, N., additional, Perier, M.C., additional, Piot, O., additional, Plaisance, P., additional, Plaud, B., additional, Plu, I., additional, Raphalen, J.H., additional, Raux, M., additional, Revaux, F., additional, Ricard, J.D., additional, Richard, C., additional, Riou, B., additional, Roussin, F., additional, Santoli, F., additional, Schortgen, F., additional, Sharshar, T., additional, Sideris, G., additional, Spaulding, C., additional, Teboul, J.L., additional, Timsit, J.F., additional, Tourtier, J.P., additional, Tuppin, P., additional, Ursat, C., additional, Varenne, O., additional, Vieillard-Baron, A., additional, Voicu, S., additional, Wahbi, K., additional, and Waldmann, V., additional

Published
2023
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5. Comprehensive Assessment of Coronary Artery Disease in Sports-Related Sudden Cardiac Arrest

Author

Karam, Nicole, Pechmajou, Louis, Dumas, Florence, Bougouin, Wulfran, Sharifzadehgan, Ardalan, Beganton, Frankie, Bonnet, Guillaume, Jost, Daniel, Lamhaut, Lionel, Varenne, Olivier, Aubry, Pierre, Sideris, Georgios, Spaulding, Christian, Cariou, Alain, Marijon, Eloi, Jouven, Xavier, Adnet, F, Agostinucci, JM, Aissaoui-Balanant, N, Algalarrondo, V, Alla, F, Alonso, C, Amara, W, Annane, D, Antoine, C, Aubry, P, Azoulay, E, Beganton, F, Benhamou, D, Bougouin, W, Bruel, C, Brun Buisson, C, Bruneval, P, Cariou, A, Carli, P, Cerf, C, Chaib, A, Chastre, J, Cholley, B, Cohen, Y, Combes, A, Cornaglia, C, Coulaud, JM, Da Silva, D, Das, V, Deye, N, Dhonneur, G, Diehl, JL, Dinanian, S, Domanski, L, Dreyfuss, D, Duboc, D, Dubois-Rande, JL, Mansencal, N, Duchateau, FX, Duguet, A, Dumas, F, Empana, JP, Extramiana, F, Fartoukh, M, Fenioux, C, Fraisse, F, Gabbas, M, Gandjbakhch, E, Guidet, B, Halimi, F, Henry, P, Hidden Lucet, F, Jabre, P, Jacob, L, Joseph, L, Jost, D, Journois, D, Jouven, X, Karam, N, Lacotte, J, Lahlou-Laforet, K, Lamhaut, L, Lanceleur, A, Langeron, O, Lanoe, V, Lavergne, T, Lecarpentier, E, Leenhardt, A, Lellouche, N, Lemiale, V, Linval, F, Loeb, T, Ludes, B, Mansouri, N, Marijon, E, Marty, J, Maury, E, Maxime, V, Mekontso-Dessaps, A, Mira, JP, Misset, B, Monnet, X, Montalescot, G, Narayanan, K, Nicolas-Robin, A, Perier, MC, Piot, O, Plu, I, Revaux, F, Ricard, JD, Richard, C, Riou, B, Rouby, JJ, Santoli, F, Schortgen, F, Sharshar, T, Sideris, G, Similowski, T, Simon, A, Spaulding, C, Steg, G, Teboul, JL, Timsit, JF, Tourtier, JP, Tuppin, P, Ursat, C, Varenne, O, Vieillard-Baron, A, Voicu, S, Wahbi, K, Waldmann, V, and Wolff, M

Published
2018
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8. A Different Era for Malignant Otitis Externa: The Non-Diabetic and Non-Immunocompromised Patients

Author

Sideris, G. Latzonis, J. Avgeri, C. Malamas, V. Delides, A. Nikolopoulos, T.

Abstract

BACKGROUND: Τo investigate the differences in regard to the clinical, laboratory, and imaging findings as well as the treatment course between diabetic and non-diabetic, non-immunocompromised patients with malignant otitis externa. METHODS: A total of 36 hospitalized patients diagnosed with malignant otitis externa between January 2011 and December 2020 were divided into 2 groups according to their medical history, blood glucose, and glycated hemoglobin levels. RESULTS: Thirty-two patients were diabetic (group A) and 4 were non-diabetic, non-immunocompromised (group B). Otalgia was present in all patients (100%), followed by otorrhoea (67%) and edema (64%). Polyps were present in 18 patients (50%). Pseudomonas aeruginosa was isolated in 16 out of 25 positive cultures (64%). Four patients of group A and none of group B underwent surgery. Five patients of group A and none of group B had at least 1 cranial nerve involvement. The mean age was 77.22 ± 8.17 for group A and 47.25 ± 3.59 for group B (P < .001). No statistical significance was observed in regards to major symptoms, inflammatory markers (white blood cell, C-reactive protein, and erythrocyte sedimenta-tion rate), positive imaging, and microbiological findings between the 2 groups. The average days of hospitalization were 42.41 ± 31.06 for group A and 10.25 ± 2.63 for group B (P < .049). Four diabetic patients died. CONCLUSION: Non-diabetic, non-immunocompromised adult patients with malignant otitis externa had a better response to antibiotic therapy and a shorter length of hospitalization. A high clinical suspicion for malignant otitis externa should always raise in cases of otitis externa that fail to respond in a topic and/or oral antibiotic treatment for more than a week. © 2022, AVES. All rights reserved.

Published
2022

12. The long-term need for calcium supplementation after incidental parathyroidectomy

Author

Avgeri, T.-C. Sideris, G. Maragoudakis, P. Papadopoulos, I. Nikolopoulos, T. Delides, A.

Abstract

Objectives: Hypocalcaemia and hypoparathyroidism are the most frequent complications of total thyroidectomy that may result in the need for lifelong calcium supplementation. This study aims to investigate the impact of incidental parathyroidectomy on short- and long-term hypocalcaemia. Methods: This retrospective study was conducted on patients who underwent total thyroidectomy with or without central neck dissection between March 2016 to May 2018. All procedures were performed by three surgeons with similar experience levels. Histopathology reports were reviewed, the number of resected parathyroid glands and the underlying pathology reports were recorded, and the patients were divided into two groups; groups A and B comprised those with and without parathyroid glands respectively. The incidence rates of short- and long-term hypocalcaemia were recorded. The former was obtained through blood tests during hospitalisation and the latter via phone calls to patients 3, 6, and 12 months postoperatively. Results: A total of 116 patients participated, 18 (15.5%) in group A and 98 (84.5%) in group B. No statistical significance was detected between the two groups regarding early postoperative (p = 0.109) or long-term hypocalcaemia (p = 0.48). These results were similar in patients with cancer (n = 40) (p = 0.855, p = 0.08). Conclusion: Incidental parathyroidectomy of one parathyroid gland was not correlated with a higher incidence of hypocalcaemia, even in cases with thyroid cancer. © 2021 The Authors

Published
2021

14. Early detecting cervical necrotizing fasciitis from deep neck infections: a study of 550 patients

Author

Sideris, G. Sapountzi, M. Malamas, V. Papadimitriou, N. Maragkoudakis, P. Delides, A.

Abstract

Purpose: The aim of this retrospective review study is to evaluate Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score as an indicative parameter in early detecting cervical necrotizing fasciitis (CNF) from deep neck infections (DNI). Methods: We reviewed 12 cases of CNF and 538 cases of non-necrotizing deep neck infection hospitalized in our hospital over the last decade. Cervical necrotizing fasciitis was histologically confirmed. Results: Using an LRINEC score of 6 as a cutoff sensitivity was calculated at 100% (95% CI 99.9–100) and specificity 72.5% (95% CI 72.4–72.6). Negative predicted value (NPV) was 100% and positive predicted value (PPV) was 7.5%. C-reactive protein (CRP), white blood count (WBC), and glucose (Glu) levels have a higher correlation. Haemoglobin (Hb), sodium (Na), and creatinine (Cr) do not seem to have a big impact in our study. Conclusion: LRINEC score proves to be a useful “rule-out” tool that works on the safe side with high sensitivity and poor specificity. WBC, CRP, and Glu seem to be the most significant variables of the LRINEC score. Hb, Na, and Cr make the score safer. Decision for surgery must be based on medical history, clinical symptoms and signs, imaging findings, and laboratory tests and not according to the LRINEC score itself. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.

Published
2021

15. Modifying effect of dual antiplatelet therapy on incidence of stent thrombosis according to implanted drug-eluting stent type

Author

Camenzind, Edoardo, Boersma, Eric, Wijns, William, Mauri, Laura, Rademaker-Havinga, Tessa, Ordoubadi, Farzin Fath, Suttorp, Maarten J., Al Kurdi, Mohammad, Steg, Ph Gabriel, Camenzind, E, Mauri, L, OʼNeill, W, Serruys, P W, Steg, PhG, Wijns, W, Verheugt, FWA, Bertrand, ME, Califf, R, DeMets, D, Wallentin, L, Bocksch, W, Bosmans, J, Garcia, H, Garg, S, Hanet, C, Herrman, J-PR, Kelbaek, H, Mc Fadden, E, Radke, PW, Rutsch, W, Tilsted, HH, Wykrzykowska, J, Alvarez, C, Rodriguez, A, Meredith, I, Muller, D, Whitbourn, R, Worthley, S, Whelan, A, Walters, D, Shetty, S, New, G, Cox, S, Batra, R, van Gaal, W, Bellamy, G, Mayr, H, Heigert, M, Huber, K, Leisch, F, Wijns, W, Desmet, W, Boland, J, Schroeder, E, Chenu, P, Legrand, V, Labinaz, M, Teefy, P, Bertrand, O, Gao, R, Ge, J, Kala, P, Cervinka, P, Ureña, P, Hartikainen, J, Steg, G, Fajadet, J, Carrie, D, Gilard, M, Barragan, P, Lablanche, J-M, Koning, R, Eltchaninoff, H, Darremont, O, Leroy, F, Bertrand, B, Robert, G, Schiele, F, Chassaing, S, Bressollette, E, Brunel, P, Quilliet, L, Brunet, J, Pansieri, M, Sideris, G, Stratiev, V, Teiger, E, Lebreton, H, Bonnet, J-L, Karsenty, B, Delarche, N, Lusson, J-R, Cassagnes, J, Brachmann, J, Kurowski, V, Buerke, M, Schieffer, B, Scholtz, W, Wiemer, M, Fichtlscherer, S, Schächinger, V, Kupatt, C, Boekstegers, P, Genth-Zotz, S, Bode, C, Frey, N, Neumann, F-J, Witzenbichler, B, Pels, K, Strasser, R, Kuck, K-H, Hauptmann, K-E, Baldus, S, Heitzer, T, Haude, M, Hoffmann, E, Jung, W, Hoffmann, S, Schmitt, C, Dissmann, M, Pauschinger, M, Werner, G, Braun-Delleus, R, Burkhardt, D, Manz, M, Voudris, V, Sionis, D, Kang-Yin, M-L, Tse, T-S, Merkely, B, Mehta, A, Parikh, K, Kumar, V, Chandra, P, Rath, P, Hiremath, S, Crean, P, Daly, K, Kornowski, R, Kerner, A, Mosseri, M, Jafari, G, Giudice, P, Trani, C, Manari, A, Prati, F, Pangrazi, A, Bolognese, L, Jeong, M-H, Kim, M-Y, Kim, H-S, Park, S-J, Erglis, A, Kalnins, A, Wagner, D, Zambahari, R, Ong, T-K, Sim, K, den Heijer, P, Appelman, Y, Suttorp, M-J, de Smet, B, Koolen, J, Stella, P, Harding, S, Warwick, J, Maslowski, A, Abernethy, M, Devlin, G, Rotevatn, S, Myreng, Y, Ciecwierz, D, Peruga, J, Reczuch, K, Campante Teles, R, Farto, P, Abreu, E, Leitão-Marques, A, Pereira, H, Vinereanu, D, Alkasab, S, Mhish, H, Al Kurdi, M, Al Turki, F, Wong, P, Teo, S-G, Goicolea Ruigomez, F-J, Valdés Chávarri, M, Bethencourt Gonzalez, A, Iñiguez Romo, A, López Minguez, J, Hernández García, J-M, Diaz Fernández, J, Ruiz Salmeron, R, Martinez Elbal, L, Zueco, J, López-Palop, RF, Melgares, R, Diderholm, E, Kåregren, A, Herterich, O, Olivencrona, G, Fröbert, O, Roffi, M, Verin, V, Girod, G, Vuilliomenet, A, Hsieh, I-C, Wu, C-J, Gershlick, A, Densem, C, Doshi, S, Manoharan, G, McCarthy, P, De Belder, M, Mills, J, Fath-Ordoubadi, F, Simpson, I, Greenwood, J, Chamberlain-Webber, R, Khan, Z, Cotton, J, Gunning, M, Smith, D, Talwar, S, Holmberg, S, Purcell, I, Anderson, R, Alamgir, F, Beatt, K, Kelly, P, Moussavian, M, Aji, J, Prashad, R, Zankar, A, Banerjee, S, Lewis, S, McLaurin, B, Douglas, J, Brener, S, Gupta, A, Walters, L, Driesman, M, Aycock, R, Mego, C, Fisher, D, Frankel, R, and Satler, L

Published
2014
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16. Cervical necrotizing fasciitis affects only immunocompromized patients? Diagnostic challenges, treatment outcomes and clinical management of eleven immunocompetent adult patients with a still fatal disease

Author

Sideris, G. Nikolopoulos, T. Delides, A.

Abstract

Purpose: Cervical Necrotizing fasciitis (CNF) has been reported as an unusual rapidly progressive, life-threatening, inflammatory disease that is known to affect predominately immunocompromised patients. Few case reports have been sporadically published involving immunocompetent adults. This is the first study presents a series of immunocompetent CNF patients. Materials and methods: A retrospective chart review study was performed on immunocompetent adults with CNF from January 2003 to December 2019. The diagnosis was histologically confirmed. We analyzed epidemiological, clinical, laboratory and imaging findings and discussed them along with the treatment plan. Results: A total of eleven adult patients were included in the study. The average age was 43 years, ranging from 17 to 62 years. The average hospitalization time was 28 days, ranging from 10 to 129 days. All patients presented with cervical erythema and odynophagia. The causative factors are known in nine patients. Tissue cultures demonstrated mixed flora in six patients. Seven underwent a temporary tracheostomy. Wide neck exploration incisions were performed in all patients as the diagnosis was established after imaging findings. In nine cases the anterior-upper mediastinum was affected but only in two patients extension of the surgical planes to the mediastinum was performed. Four patients developed polyserositis. Nine patients survived and two developed multiorgan failure and died. Conclusion: There seem to be no differences between immunocompetent and immunocompromised CNF patients, in regards to clinical, imaging and laboratory findings as well as their treatment plan. © 2020 Elsevier Inc.

Published
2020

19. The role of liver transplantation for colorectal liver metastases: A systematic review and pooled analysis

Author

Giannis, D. Sideris, G. Kakos, C.D. Katsaros, I. Ziogas, I.A.

Abstract

Background: Liver transplantation (LT) has gained interest in the treatment of unresectable colorectal liver metastases (CRLM) over the last two decades. Despite the initial poor outcomes, recent reports from countries with graft abundance have provided further insights in the potential of LT as a treatment for unresectable CRLM. Methods: A systematic literature search was conducted in the MEDLINE (PubMed), Embase, Scopus, Cochrane Library, Google Scholar, Virtual Health Library, Clinicaltrials.gov, and Web of Science databases (end-of-search date: January 27th, 2020) to identify relevant studies. Pooled overall and recurrence-free survival analysis at 6 months, 1, 2, 3, and 5 years was conducted with the Kaplan-Meier (Product Limit) method. Results: Eighteen studies comprising 110 patients were included. The population consisted of 59.8% males with a mean age of 52.3 ± 9.3 years. CRLM diagnosis was synchronous in 83%, while 99% received chemotherapy, and 39% received liver resection prior to LT. The mean time from primary tumor resection to LT was 39.5 ± 32.5 months, the mean post-LT follow-up was 32.1 ± 22.2 months, and the mean time to recurrence was 15.0 ± 11.3 months. The pooled 6-month, 1-, 2-, 3-, and 5-year overall survival rates were 95.7% (95%CI: 89.1%–98.4%), 88.1% (95%CI: 79.6%–93.2%), 74.6% (95%CI: 64.2%–82.3%), 58.4% (95%CI: 47.2%–62.0%), and 50.5% (95%CI: 39.0%–61.0%), respectively. The pooled 6-months, 1-, 2-, 3-, and 5-year recurrence-free survival rates were 77.2% (95%CI: 67.2%–84.5%), 59.9% (95%CI: 49.0%–69.2%), 42.4% (95%CI: 31.8%–52.6%), 30.7% (95%CI: 20.9%–41.1%), and 25.6% (95%CI: 16.2%–36.0%), respectively. Conclusion: LT should be considered in patients with unresectable liver-only CRLM under strict selection criteria and only under well-designed research protocols. Ongoing studies are expected to further elucidate the indications and prognosis of patients undergoing LT for unresectable CRLM. © 2020 Elsevier Inc.

Published
2020

21. Sudden Cardiac Arrest in Young Women

Author

Weizman, Orianne, primary, Sharifzadehgan, Ardalan, additional, Bougouin, Wulfran, additional, Narayanan, Kumar, additional, Tence, Noémie, additional, Dumas, Florence, additional, Waldmann, Victor, additional, Lamhaut, Lionel, additional, Jost, Daniel, additional, Wahbi, Karim, additional, Varenne, Olivier, additional, Garcia, Rodrigue, additional, Karam, Nicole, additional, Cariou, Alain, additional, Jouven, Xavier, additional, Marijon, Eloi, additional, Agostinucci, JM, additional, Algalarrondo, V, additional, Alla, F, additional, Alonso, C, additional, Amara, W, additional, Annane, D, additional, Antoine, C, additional, Aubry, P, additional, Azoulay, E, additional, Beganton, F, additional, Benhamou, D, additional, Billon, C, additional, Bougouin, W, additional, Boutet, J, additional, Bruel, C, additional, Bruneval, P, additional, Cariou, A, additional, Carli, P, additional, Casalino, E, additional, Cerf, C, additional, Chaib, A, additional, Cholley, B, additional, Cohen, Y, additional, Combes, A, additional, Coulaud, JM, additional, Crahes, M, additional, Da Silva, D, additional, Das, V, additional, Demoule, A, additional, Denjoy, I, additional, Deye, N, additional, Dhonneur, G, additional, Diehl, JL, additional, Dinanian, S, additional, Domanski, L, additional, Dreyfuss, D, additional, Duboc, D, additional, Dubois-Rande, JL, additional, Dumas, F, additional, Empana, JP, additional, Extramiana, F, additional, Fartoukh, M, additional, Fieux, F, additional, Gabbas, M, additional, Gandjbakhch, E, additional, Geri, G, additional, Guidet, B, additional, Halimi, F, additional, Henry, P, additional, Hidden Lucet, F, additional, Jabre, P, additional, Jacob, L, additional, Joseph, L, additional, Jost, D, additional, Jouven, X, additional, Karam, N, additional, Lacotte, J, additional, Lapostolle, F, additional, Lahlou-Laforet, K, additional, Lamhaut, L, additional, Lanceleur, A, additional, Langeron, O, additional, Lavergne, T, additional, Lecarpentier, E, additional, Leenhardt, A, additional, Lellouche, N, additional, Lemiale, V, additional, Lemoine, F, additional, Linval, F, additional, Loeb, T, additional, Ludes, B, additional, Maltret, A, additional, Mansencal, N, additional, Mansouri, N, additional, Marijon, E, additional, Marty, J, additional, Maury, E, additional, Maxime, V, additional, Megarbane, B, additional, Mekontso-Dessap, A, additional, Mira, JP, additional, Monnet, X, additional, Narayanan, K, additional, Ngoyi, N, additional, Perier, MC, additional, Piot, O, additional, Plaisance, P, additional, Plu, I, additional, Raux, M, additional, Revaux, F, additional, Ricard, JD, additional, Richard, C, additional, Riou, B, additional, Roussin, F, additional, Santoli, F, additional, Schortgen, F, additional, Sharifzadehgan, A, additional, Sideris, G, additional, Spaulding, C, additional, Teboul, JL, additional, Timsit, JF, additional, Tuppin, P, additional, Ursat, C, additional, Varenne, O, additional, Vieillard-Baron, A, additional, Voicu, S, additional, Wahbi, K, additional, and Waldmann, V, additional

Published
2021
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30. HIV Infection and Long‐Term Residual Cardiovascular Risk After Acute Coronary Syndrome

Author

Boccara, Franck, primary, Mary‐Krause, Murielle, additional, Potard, Valérie, additional, Teiger, Emmanuel, additional, Lang, Sylvie, additional, Hammoudi, Nadjib, additional, Chauvet, Marion, additional, Ederhy, Stéphane, additional, Dufour‐Soulat, Laurie, additional, Ancedy, Yann, additional, Nhan, Pascal, additional, Adavane, Saroumadi, additional, Steg, Ph. Gabriel, additional, Funck‐Brentano, Christian, additional, Costagliola, Dominique, additional, Cohen, Ariel, additional, Weber, S., additional, Wahbi, K., additional, Beaufils, P., additional, Henri, P., additional, Sideris, G., additional, Thomas, D., additional, Montalescot, G., additional, Beygui, F., additional, Meuleman, C., additional, Janower, S., additional, Raoux, F., additional, Dufaitre, G., additional, Benyounes, N., additional, Michel, P. L., additional, Petillon, B., additional, Hammoudi, N., additional, Gueret, P., additional, Dubois‐Rande, J. L., additional, Teiger, E., additional, Lim, P., additional, Slama, M., additional, Colin, P., additional, Saudubray, C., additional, Dubourg, O., additional, Milleron, O., additional, Gallet, B., additional, Duclos, F., additional, Godard, S., additional, Fuchs, L., additional, Dormagen, V., additional, Lewy, P., additional, Cattan, S., additional, Nallet, O., additional, Grollier, G., additional, Shayne, J., additional, Wolf, J. E., additional, Cottin, Y., additional, Machecourt, J., additional, Bouvaist, H., additional, Finet, G., additional, De Breyne, B., additional, Trochu, J. N., additional, Baudouy, M., additional, Ferrari, E., additional, Benhamou, M., additional, Allal, J., additional, Coisne, D., additional, Le Breton, H., additional, Bedossa, M., additional, Puel, J., additional, Elbaz, M., additional, Larifla, L., additional, Matheron, S., additional, Landman, R., additional, Fremont, G., additional, Spiridon, G., additional, Blanche, P., additional, Morini, J. P., additional, Sicard, D., additional, Zeller, V., additional, Batisse, D., additional, Clevenbergh, P., additional, Cessot, G., additional, Dohin, E., additional, Valantin, M. A., additional, Khelifa, S., additional, Girard, P. M., additional, Lallemand, F., additional, Lefebvre, B., additional, Laporte, J. P., additional, Meynard, J. L., additional, Bideault, H., additional, Picard, O., additional, Meyohas, M. C., additional, Campa, P., additional, Tredup, J., additional, Fonquernie, L., additional, Raguin, G., additional, Molina, J. M., additional, Furco, A., additional, Gharakanian, S., additional, Vincensini, J. P., additional, Guiard‐Schmid, J. B., additional, Pialoux, G., additional, Cardon, B., additional, Lascaux, A. S., additional, Chaix, F., additional, Lesprit, P., additional, Fior, R., additional, Boue, F., additional, Dupont, C., additional, Bellier, C., additional, Blanc, A., additional, Lambert, T., additional, Touahri, T., additional, Force, G., additional, de Truchis, P., additional, Compagnucci‐Seguenot, M. A., additional, Cahitte, I., additional, Roudière, L., additional, Techer, M. E., additional, Thelpin, P., additional, Troisvallets, D., additional, Lepretre, A., additional, Echard, M., additional, Le Mercier, Y., additional, Houlbert, D., additional, Dargere, S., additional, Bazin, C., additional, Verdon, R., additional, De Goer, B., additional, Duong, M., additional, Chavanet, P., additional, Gozlan, E., additional, Leclercq, P., additional, Brunel‐Dal Mas, F., additional, Durant, J., additional, Heudier, P., additional, Brunet‐François, C., additional, Le Moal, G., additional, Chapplin, J. M., additional, Arvieux, C., additional, Chaumentin, G., additional, Guerin, B., additional, Bonnet, E., additional, Poinsignon, Y., additional, Boulard, F., additional, De Lacroix, I., additional, Goerger‐Sow, M. T., additional, Kirstetter, M., additional, Volstein, M., additional, Laylavoix, F., additional, Copin, X., additional, and Ceppi, C., additional

Published
2020
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36. Modifying effect of dual antiplatelet therapy on incidence of stent thrombosis according to implanted drug-eluting stent type

Author

Camenzind, Edoardo, Boersma, Eric, Wijns, William, Mauri, Laura, Rademaker-Havinga, Tessa, Ordoubadi, Farzin Fath, Suttorp, Maarten J., Al Kurdi, Mohammad, Steg, Ph Gabriel, Camenzind, E., Mauri, L., O'Neill, W., Serruys, P W., Steg, PhG, Wijns, W., Verheugt, FWA, Bertrand, ME, Califf, R., DeMets, D., Wallentin, L., Bocksch, W., Bosmans, J., Garcia, H., Garg, S., Hanet, C., Herrman, J-PR, Kelbaek, H., Mc Fadden, E., Radke, PW, Rutsch, W., Tilsted, HH, Wykrzykowska, J., Alvarez, C., Rodriguez, A., Meredith, I., Muller, D., Whitbourn, R., Worthley, S., Whelan, A., Walters, D., Shetty, S., New, G., Cox, S., Batra, R., van Gaal, W., Bellamy, G., Mayr, H., Heigert, M., Huber, K., Leisch, F., Desmet, W., Boland, J., Schroeder, E., Chenu, P., Legrand, V., Labinaz, M., Teefy, P., Bertrand, O., Gao, R., Ge, J., Kala, P., Cervinka, P., Ureña, P., Hartikainen, J., Steg, G., Fajadet, J., Carrie, D., Gilard, M., Barragan, P., Lablanche, J-M, Koning, R., Eltchaninoff, H., Darremont, O., Leroy, F., Bertrand, B., Robert, G., Schiele, F., Chassaing, S., Bressollette, E., Brunel, P., Quilliet, L., Brunet, J., Pansieri, M., Sideris, G., Stratiev, V., Teiger, E., Lebreton, H., Bonnet, J-L, Karsenty, B., Delarche, N., Lusson, J-R, Cassagnes, J., Brachmann, J., Kurowski, V., Buerke, M., Schieffer, B., Scholtz, W., Wiemer, M., Fichtlscherer, S., Schächinger, V., Kupatt, C., Boekstegers, P., Genth-Zotz, S., Bode, C., Frey, N., Neumann, F-J, Witzenbichler, B., Pels, K., Strasser, R., Kuck, K-H, Hauptmann, K-E, Baldus, S., Heitzer, T., Haude, M., Hoffmann, E., Jung, W., Hoffmann, S., Schmitt, C., Dissmann, M., Pauschinger, M., Werner, G., Braun-Delleus, R., Burkhardt, D., Manz, M., Voudris, V., Sionis, D., Kang-Yin, M-L, Tse, T-S, Merkely, B., Mehta, A., Parikh, K., Kumar, V., Chandra, P., Rath, P., Hiremath, S., Crean, P., Daly, K., Kornowski, R., Kerner, A., Mosseri, M., Jafari, G., Giudice, P., Trani, C., Manari, A., Prati, F., Pangrazi, A., Bolognese, L., Jeong, M-H, Kim, M-Y, Kim, H-S, Park, S-J, Erglis, A., Kalnins, A., Wagner, D., Zambahari, R., Ong, T-K, Sim, K., den Heijer, P., Appelman, Y., Suttorp, M-J, de Smet, B., Koolen, J., Stella, P., Harding, S., Warwick, J., Maslowski, A., Abernethy, M., Devlin, G., Rotevatn, S., Myreng, Y., Ciecwierz, D., Peruga, J., Reczuch, K., Campante Teles, R., Farto, P., Abreu, E., Leitão-Marques, A., Pereira, H., Vinereanu, D., Alkasab, S., Mhish, H., Al Kurdi, M., Al Turki, F., Wong, P., Teo, S-G, Goicolea Ruigomez, F-J, Valdés Chávarri, M., Bethencourt Gonzalez, A., Iñiguez Romo, A., López Minguez, J., Hernández García, J-M, Diaz Fernández, J., Ruiz Salmeron, R., Martinez Elbal, L., Zueco, J., López-Palop, RF, Melgares, R., Diderholm, E., Kåregren, A., Herterich, O., Olivencrona, G., Fröbert, O., Roffi, M., Verin, V., Girod, G., Vuilliomenet, A., Hsieh, I-C, Wu, C-J, Gershlick, A., Densem, C., Doshi, S., Manoharan, G., McCarthy, P., De Belder, M., Mills, J., Fath-Ordoubadi, F., Simpson, I., Greenwood, J., Chamberlain-Webber, R., Khan, Z., Cotton, J., Gunning, M., Smith, D., Talwar, S., Holmberg, S., Purcell, I., Anderson, R., Alamgir, F., Beatt, K., Kelly, P., Moussavian, M., Aji, J., Prashad, R., Zankar, A., Banerjee, S., Lewis, S., McLaurin, B., Douglas, J., Brener, S., Gupta, A., Walters, L., Driesman, M., Aycock, R., Mego, C., Fisher, D., Frankel, R., and Satler, L.

Subjects
animal structures, cardiovascular diseases, equipment and supplies
Abstract

Aim To investigate the putative modifying effect of dual antiplatelet therapy (DAPT) use on the incidence of stent thrombosis at 3 years in patients randomized to Endeavor zotarolimus-eluting stent (E-ZES) or Cypher sirolimus-eluting stent (C-SES). Methods and results Of 8709 patients in PROTECT, 4357 were randomized to E-ZES and 4352 to C-SES. Aspirin was to be given indefinitely, and clopidogrel/ticlopidine for ≥3 months or up to 12 months after implantation. Main outcome measures were definite or probable stent thrombosis at 3 years. Multivariable Cox regression analysis was applied, with stent type, DAPT, and their interaction as the main outcome determinants. Dual antiplatelet therapy adherence remained the same in the E-ZES and C-SES groups (79.6% at 1 year, 32.8% at 2 years, and 21.6% at 3 years). We observed a statistically significant (P = 0.0052) heterogeneity in treatment effect of stent type in relation to DAPT. In the absence of DAPT, stent thrombosis was lower with E-ZES vs. C-SES (adjusted hazard ratio 0.38, 95% confidence interval 0.19, 0.75; P = 0.0056). In the presence of DAPT, no difference was found (1.18; 0.79, 1.77; P = 0.43). Conclusion A strong interaction was observed between drug-eluting stent type and DAPT use, most likely prompted by the vascular healing response induced by the implanted DES system. These results suggest that the incidence of stent thrombosis in DES trials should not be evaluated independently of DAPT use, and the optimal duration of DAPT will likely depend upon stent type (Clinicaltrials.gov number NCT00476957)

Published
2017

40. Should We Perform an Immediate Coronary Angiogram in All Patients After Cardiac Arrest?

Author

Bougouin, Wulfran, primary, Dumas, Florence, additional, Karam, Nicole, additional, Maupain, Carole, additional, Marijon, Eloi, additional, Lamhaut, Lionel, additional, Jost, Daniel, additional, Geri, Guillaume, additional, Beganton, Frankie, additional, Varenne, Olivier, additional, Spaulding, Christian, additional, Jouven, Xavier, additional, Cariou, Alain, additional, Adnet, F., additional, Agostinucci, J.M., additional, Aissaoui-Balanant, N., additional, Albuisson, J., additional, Algalarrondo, V., additional, Alla, F., additional, Annane, D., additional, Antoine, C., additional, Aubry, P., additional, Azoulay, E., additional, Beganton, F., additional, Benhamou, D., additional, Bougouin, W., additional, Bruel, C., additional, Cariou, A., additional, Carli, P., additional, Cerf, C., additional, Chaib, A., additional, Chastre, J., additional, Cohen, Y., additional, Combes, A., additional, Cornaglia, C., additional, Da Silva, D., additional, Das, V., additional, Demoule, A., additional, Deye, N., additional, Dhonneur, G., additional, Diehl, J.L., additional, Dinanian, S., additional, Domanski, L., additional, Dreyfuss, D., additional, Duboc, D., additional, Dubois-Rande, J.L., additional, Dubourg, O., additional, Duchateau, F.X., additional, Dumas, F., additional, Empana, J.P., additional, Extramiana, F., additional, Fagon, J.Y., additional, Fartoukh, M., additional, Fenioux, C., additional, Fieux, F., additional, Fraisse, F., additional, Gabbas, M., additional, Gandjbakhch, E., additional, Guidet, B., additional, Henry, P., additional, Hidden Lucet, F., additional, Jabre, P., additional, Jacob, L., additional, Joseph, L., additional, Jost, D., additional, Journois, D., additional, Jouven, X., additional, Karam, N., additional, Kassim, H., additional, Lahlou-Laforet, K., additional, Lamhaut, L., additional, Lanceleur, A., additional, Langeron, O., additional, Lanoe, V., additional, Lecarpentier, E., additional, Leenhardt, A., additional, Lellouche, N., additional, Lemiale, V., additional, Linval, F., additional, Loeb, T., additional, Ludes, B., additional, Maltret, A., additional, Mansouri, N., additional, Mantz, J., additional, Marijon, E., additional, Marty, J., additional, Maury, E., additional, Maxime, V., additional, Mekontso-Dessaps, A., additional, Mira, J.P., additional, Monnet, X., additional, Perier, M.C., additional, Piot, O., additional, Pirraccchio, R., additional, Plu, I., additional, Raux, M., additional, Revaux, F., additional, Ricard, J.D., additional, Richard, C., additional, Riou, B., additional, Roussin, F., additional, Santoli, F., additional, Schortgen, F., additional, Sharshar, T., additional, Sideris, G., additional, Spaulding, C., additional, Teboul, J.L., additional, Timsit, J.F., additional, Tourtier, J.P., additional, Tuppin, P., additional, Ursat, C., additional, Varenne, O., additional, Vieillard-Baron, A., additional, Voicu, S., additional, and Wahbi, K., additional

Published
2018
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43. Bivalirudin infusion to reduce ventricular infarction: the open-label, randomised Bivalirudin Infusion for Ventricular InfArction Limitation (BIVAL) study

Author

Geuns, R.J.M. van, Sideris, G., Royen, N. van, Mahmoud, R. El, Diletti, R., Sollier, C. Bal Dit, Garot, J., Hoeven, N.W. Van Der, Cortese, B., Ding, L., Lechthaler, I., Deliargyris, E.N., Anthopoulos, P., Drouet, L., Geuns, R.J.M. van, Sideris, G., Royen, N. van, Mahmoud, R. El, Diletti, R., Sollier, C. Bal Dit, Garot, J., Hoeven, N.W. Van Der, Cortese, B., Ding, L., Lechthaler, I., Deliargyris, E.N., Anthopoulos, P., and Drouet, L.

Abstract

Item does not contain fulltext, AIMS: The aim of the study was to investigate whether bivalirudin versus unfractionated heparin (UFH) reduces infarct size (IS) for primary percutaneous coronary intervention (PPCI) in large acute myocardial infarction (AMI). METHODS AND RESULTS: This multicentre open-label trial randomised 78 patients undergoing PPCI for large AMI to bivalirudin or UFH. The primary endpoint was IS, assessed by cardiac magnetic resonance (CMR) five days after PPCI. Secondary endpoints included index of microcirculatory resistance (IMR), CMR-assessed microvascular obstruction (MVO) and ejection fraction, and biomarkers for thrombin activity and cell injury. No difference was observed in mean IS at five days (25.0+/-19.7 g for bivalirudin vs. 27.1+/-20.7 g for UFH; p=0.75). Early MVO was numerically lower with bivalirudin (5.3+/-5.8 g vs. 7.7+/-6.3 g; p=0.17), with no significant difference in ejection fraction at 90 days (54.6+/-12.0% vs. 49.1+/-12.1%; p=0.11). In the biomarkers, thrombin-antithrombin complexes were reduced by 4.8 ug/L over the first day for bivalirudin versus an increase of 1.9 ug/L in the heparin arm (p=0.0003). Acute IMR was lower (43.5+/-21.6 vs. 68.7+/-35.8 mmHgxs, respectively; p=0.014). In a planned interim analysis, an approximate 11% reduction in IS was observed with bivalirudin; the trial was discontinued for futility. CONCLUSIONS: This study did not achieve its primary endpoint of significant infarct size reduction in PPCI by prolonged bivalirudin infusion compared to UFH, even though complete thrombin inhibition was achieved in the acute phase, with a lower myocardial microcirculation resistance at the end of the procedure.

Published
2017

45. P2778Feasability and cannulation time for percutaneous extracorporeal life support in patients with refractory cardiac arrest in a center without on-site cardiovascular surgery

Author

Voicu, S., primary, Sideris, G., additional, Dillinger, J.G., additional, Koumoulidis, A., additional, Magkoutis, N., additional, Malissin, I., additional, Deye, N., additional, Manzo-Silberman, S., additional, Logeart, D., additional, Megarbane, B., additional, and Henry, P., additional

Published
2017
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48. Liberty: sul restauro di Villa Antonietta a Palermo

Author

Dorfles, G, Sposito, A, Niglio, O, Sideris, G, LA MONICA, Marcella, Caruso, R, Vacirca, MD, Minniti, V, Distefano, A, Niglio, M, Trucoli, A, Di Salvo, S, Cipriano, C, Artale, P, Sferrazza, AK, ANGELICO, Emanuele, Ighany, G., sposito, a, Dorfles, G, Sposito, A, Niglio, O, Sideris, G, La Monica, M, Caruso, R, Vacirca, MD, Minniti, V, Distefano, A, Niglio, M, Trucoli, A, Di Salvo, S, Cipriano, C, Artale, P, Sferrazza, AK, Angelico, E, and Ighany, G

Subjects
restauro, liberty, recupero, colore, mondello, palermo, Settore ICAR/12 - Tecnologia Dell'Architettura
Abstract

Tra le moltissime costruzioni Liberty a Palermo, quest’articolo descrive Villa Antonietta, un edificio poco noto e di oscura attribuzione. Di recente è stato realizzato un’intervento di restauro; qui per brevità, si descrivono soltanto alcune questioni legate al tema del colore nel Liberty che in questa Villa sono stati riproposti con principio filologico a partire dalle preesistenze presenti a Mondello dove la Villa ha sede.

Published
2009

49. Delphi: dall'omphalos cosmico al Museo Archeologico

Author

DORFLES, G, SPOSITO, A, NIGLIO, O, SIDERIS, G, LA MONICA, M, CARUSO, R, MINNITI, V, DISTEFANO, A, MIGLIO, M, TRICOLI, A, DI SALVO, S, CIPRIANO, C, ARTALE, P, SFERRAZZA, A, ANGELICO, W, IGHANY, G., VACIRCA, Maria Desiree, SPOSITO, A., DORFLES, G, SPOSITO, A, NIGLIO, O, SIDERIS, G, LA MONICA, M, CARUSO, R, VACIRCA, MD, MINNITI, V, DISTEFANO, A, MIGLIO, M, TRICOLI, A, DI SALVO, S, CIPRIANO, C, ARTALE, P, SFERRAZZA, A, ANGELICO, W, and IGHANY, G

Subjects
progetto museografico, sito archeologico, exhibition, showcase, Settore ICAR/16 - Architettura Degli Interni E Allestimento, open-air museum, contestualizzazione, museo archeologico
Abstract

The permanent exhibition in the Archaeological Museum, which focuses on the history of the Delphic temenos and the events related to the famous oracle and omphalos, is analyzed through the complex and delicate relationship which the contemporary museum building has established with his context, as the archaeological site of Delphi can be read as an open-air museum, which was able to accumulate and settle inside its perimeter, in a variety of declinations, the architecture and the art of ancient Hellas.

Published
2009

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